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Search of human proteins with 28872780
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872780 cytosine-5-methyltransferase 3-like protein isoform
2 [Homo sapiens]
(386 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872780 cytosine-5-methyltransferase 3-like protein isoform ... 808 0.0
gi|28872778 cytosine-5-methyltransferase 3-like protein isoform ... 804 0.0
gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [H... 268 6e-72
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 253 2e-67
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 253 2e-67
gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Ho... 253 2e-67
gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [H... 251 8e-67
gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [H... 251 8e-67
gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho... 251 8e-67
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 47 3e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 47 3e-05
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 36 0.051
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 36 0.067
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 34 0.19
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 34 0.19
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 34 0.19
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 34 0.25
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] 33 0.33
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 30 2.8
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 30 2.8
gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo sa... 30 2.8
gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo sa... 30 2.8
gi|116063562 FERM domain containing 4A [Homo sapiens] 30 2.8
gi|82830424 gon-4-like isoform a [Homo sapiens] 30 3.7
gi|82830428 gon-4-like isoform b [Homo sapiens] 30 3.7
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 30 3.7
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 30 3.7
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 30 4.8
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 29 6.3
gi|149773468 RAD51 associated protein 2 [Homo sapiens] 29 6.3
>gi|28872780 cytosine-5-methyltransferase 3-like protein isoform 2
[Homo sapiens]
Length = 386
Score = 808 bits (2088), Expect = 0.0
Identities = 386/386 (100%), Positives = 386/386 (100%)
Query: 1 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ 60
MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ
Sbjct: 1 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ 60
Query: 61 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE 120
VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE
Sbjct: 61 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE 120
Query: 121 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE 180
CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE
Sbjct: 121 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE 180
Query: 181 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL 240
TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL
Sbjct: 181 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL 240
Query: 241 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR 300
VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR
Sbjct: 241 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR 300
Query: 301 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWP 360
FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWP
Sbjct: 301 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWP 360
Query: 361 TKLVKNCFLPLREYFKYFSTELTSSL 386
TKLVKNCFLPLREYFKYFSTELTSSL
Sbjct: 361 TKLVKNCFLPLREYFKYFSTELTSSL 386
>gi|28872778 cytosine-5-methyltransferase 3-like protein isoform 1
[Homo sapiens]
Length = 387
Score = 804 bits (2076), Expect = 0.0
Identities = 386/387 (99%), Positives = 386/387 (99%), Gaps = 1/387 (0%)
Query: 1 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ 60
MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ
Sbjct: 1 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ 60
Query: 61 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE 120
VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE
Sbjct: 61 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE 120
Query: 121 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE 180
CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE
Sbjct: 121 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE 180
Query: 181 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL 240
TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL
Sbjct: 181 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL 240
Query: 241 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR 300
VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR
Sbjct: 241 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR 300
Query: 301 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIR-SRHWALVSEEELSLLAQNKQSSKLAAKW 359
FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIR SRHWALVSEEELSLLAQNKQSSKLAAKW
Sbjct: 301 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSSRHWALVSEEELSLLAQNKQSSKLAAKW 360
Query: 360 PTKLVKNCFLPLREYFKYFSTELTSSL 386
PTKLVKNCFLPLREYFKYFSTELTSSL
Sbjct: 361 PTKLVKNCFLPLREYFKYFSTELTSSL 387
>gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [Homo
sapiens]
Length = 770
Score = 268 bits (685), Expect = 6e-72
Identities = 136/372 (36%), Positives = 202/372 (54%), Gaps = 32/372 (8%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ +A +V N+ ++ED C+ CG + HPLFEGG+C C+D+FL+ ++YDDDGYQS
Sbjct: 397 REQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQS 456
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC++CC G LL+C N C RC+C EC++ LVG GT+ + W CY+CLP G+L
Sbjct: 457 YCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVL 516
Query: 155 QRRRKWRSQLKAFYDR----ESENPLEMFETVPVWRRQPVRVLSLFEDIKK---ELTSLG 207
+RR+ W +L+AF+ E E P +++ +P RR+P+RVLSLF+ I L LG
Sbjct: 517 RRRKDWNVRLQAFFTSDTGLEYEAP-KLYPAIPAARRRPIRVLSLFDGIATGYLVLKELG 575
Query: 208 F----------------LESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP----- 246
+ + G +K+V DV + +K++EEWGPFDLV G +P
Sbjct: 576 IKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLS 635
Query: 247 ---PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLE 303
P F+F+ LL Y+RPK G RPFFWMF + + + D SRFLE
Sbjct: 636 NVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLE 695
Query: 304 MEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWPTKL 363
PV I + + A W N+P + V ++S + + + L W +
Sbjct: 696 CNPVMIDAIKVSAAHRARYFWGNLPGMNRIFGFPVHYTDVSNMGRGARQKLLGRSWSVPV 755
Query: 364 VKNCFLPLREYF 375
+++ F PL++YF
Sbjct: 756 IRHLFAPLKDYF 767
>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 253 bits (646), Expect = 2e-67
Identities = 137/341 (40%), Positives = 184/341 (53%), Gaps = 31/341 (9%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ + YEV+ RNIEDICI CGSL V +HPLF GG+C CK+ FL+ + YDDDGYQS
Sbjct: 476 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 535
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC+ICC G +L+CGN +C RC+C ECVD LVGPG + W CY+C GLL
Sbjct: 536 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 595
Query: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211
+RR W S+L+ F+ + +P +++ VP +R+P+RVLSLF+ I L L L
Sbjct: 596 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 655
Query: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246
D G++ +V DV +K ++EWGPFDLV G +P
Sbjct: 656 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 715
Query: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304
P F+F+RLL ARPK G RPFFW+F + + + D SRFLE
Sbjct: 716 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 775
Query: 305 EPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSL 345
PV I + A W N+P + +R A ++L L
Sbjct: 776 NPVMIDAKEVSAAHRARYFWGNLPGM-NRPLASTVNDKLEL 815
>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 253 bits (646), Expect = 2e-67
Identities = 137/341 (40%), Positives = 184/341 (53%), Gaps = 31/341 (9%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ + YEV+ RNIEDICI CGSL V +HPLF GG+C CK+ FL+ + YDDDGYQS
Sbjct: 476 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 535
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC+ICC G +L+CGN +C RC+C ECVD LVGPG + W CY+C GLL
Sbjct: 536 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 595
Query: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211
+RR W S+L+ F+ + +P +++ VP +R+P+RVLSLF+ I L L L
Sbjct: 596 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 655
Query: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246
D G++ +V DV +K ++EWGPFDLV G +P
Sbjct: 656 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 715
Query: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304
P F+F+RLL ARPK G RPFFW+F + + + D SRFLE
Sbjct: 716 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 775
Query: 305 EPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSL 345
PV I + A W N+P + +R A ++L L
Sbjct: 776 NPVMIDAKEVSAAHRARYFWGNLPGM-NRPLASTVNDKLEL 815
>gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Homo
sapiens]
Length = 723
Score = 253 bits (646), Expect = 2e-67
Identities = 137/341 (40%), Positives = 184/341 (53%), Gaps = 31/341 (9%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ + YEV+ RNIEDICI CGSL V +HPLF GG+C CK+ FL+ + YDDDGYQS
Sbjct: 287 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 346
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC+ICC G +L+CGN +C RC+C ECVD LVGPG + W CY+C GLL
Sbjct: 347 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 406
Query: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211
+RR W S+L+ F+ + +P +++ VP +R+P+RVLSLF+ I L L L
Sbjct: 407 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 466
Query: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246
D G++ +V DV +K ++EWGPFDLV G +P
Sbjct: 467 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 526
Query: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304
P F+F+RLL ARPK G RPFFW+F + + + D SRFLE
Sbjct: 527 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 586
Query: 305 EPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSL 345
PV I + A W N+P + +R A ++L L
Sbjct: 587 NPVMIDAKEVSAAHRARYFWGNLPGM-NRPLASTVNDKLEL 626
>gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [Homo
sapiens]
Length = 845
Score = 251 bits (641), Expect = 8e-67
Identities = 127/327 (38%), Positives = 182/327 (55%), Gaps = 32/327 (9%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ +A +V N+ ++ED C+ CG + HPLFEGG+C C+D+FL+ ++YDDDGYQS
Sbjct: 409 REQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQS 468
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC++CC G LL+C N C RC+C EC++ LVG GT+ + W CY+CLP G+L
Sbjct: 469 YCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVL 528
Query: 155 QRRRKWRSQLKAFYDR----ESENPLEMFETVPVWRRQPVRVLSLFEDIKK---ELTSLG 207
+RR+ W +L+AF+ E E P +++ +P RR+P+RVLSLF+ I L LG
Sbjct: 529 RRRKDWNVRLQAFFTSDTGLEYEAP-KLYPAIPAARRRPIRVLSLFDGIATGYLVLKELG 587
Query: 208 F----------------LESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP----- 246
+ + G +K+V DV + +K++EEWGPFDLV G +P
Sbjct: 588 IKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLS 647
Query: 247 ---PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLE 303
P F+F+ LL Y+RPK G RPFFWMF + + + D SRFLE
Sbjct: 648 NVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLE 707
Query: 304 MEPVTIPDVHGGSLQNAVRVWSNIPAI 330
PV I + + A W N+P +
Sbjct: 708 CNPVMIDAIKVSAAHRARYFWGNLPGM 734
>gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [Homo
sapiens]
Length = 833
Score = 251 bits (641), Expect = 8e-67
Identities = 127/327 (38%), Positives = 182/327 (55%), Gaps = 32/327 (9%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ +A +V N+ ++ED C+ CG + HPLFEGG+C C+D+FL+ ++YDDDGYQS
Sbjct: 397 REQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQS 456
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC++CC G LL+C N C RC+C EC++ LVG GT+ + W CY+CLP G+L
Sbjct: 457 YCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVL 516
Query: 155 QRRRKWRSQLKAFYDR----ESENPLEMFETVPVWRRQPVRVLSLFEDIKK---ELTSLG 207
+RR+ W +L+AF+ E E P +++ +P RR+P+RVLSLF+ I L LG
Sbjct: 517 RRRKDWNVRLQAFFTSDTGLEYEAP-KLYPAIPAARRRPIRVLSLFDGIATGYLVLKELG 575
Query: 208 F----------------LESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP----- 246
+ + G +K+V DV + +K++EEWGPFDLV G +P
Sbjct: 576 IKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLS 635
Query: 247 ---PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLE 303
P F+F+ LL Y+RPK G RPFFWMF + + + D SRFLE
Sbjct: 636 NVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLE 695
Query: 304 MEPVTIPDVHGGSLQNAVRVWSNIPAI 330
PV I + + A W N+P +
Sbjct: 696 CNPVMIDAIKVSAAHRARYFWGNLPGM 722
>gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Homo
sapiens]
Length = 853
Score = 251 bits (641), Expect = 8e-67
Identities = 127/327 (38%), Positives = 182/327 (55%), Gaps = 32/327 (9%)
Query: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
R+ +A +V N+ ++ED C+ CG + HPLFEGG+C C+D+FL+ ++YDDDGYQS
Sbjct: 417 REQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQS 476
Query: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
YC++CC G LL+C N C RC+C EC++ LVG GT+ + W CY+CLP G+L
Sbjct: 477 YCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVL 536
Query: 155 QRRRKWRSQLKAFYDR----ESENPLEMFETVPVWRRQPVRVLSLFEDIKK---ELTSLG 207
+RR+ W +L+AF+ E E P +++ +P RR+P+RVLSLF+ I L LG
Sbjct: 537 RRRKDWNVRLQAFFTSDTGLEYEAP-KLYPAIPAARRRPIRVLSLFDGIATGYLVLKELG 595
Query: 208 F----------------LESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP----- 246
+ + G +K+V DV + +K++EEWGPFDLV G +P
Sbjct: 596 IKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLS 655
Query: 247 ---PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLE 303
P F+F+ LL Y+RPK G RPFFWMF + + + D SRFLE
Sbjct: 656 NVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLE 715
Query: 304 MEPVTIPDVHGGSLQNAVRVWSNIPAI 330
PV I + + A W N+P +
Sbjct: 716 CNPVMIDAIKVSAAHRARYFWGNLPGM 742
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 9/102 (8%)
Query: 53 CICCGSLQVHTQ------HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLL 106
C CG H Q HP + IC C ++ D DG C C G L+
Sbjct: 133 CTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLI 192
Query: 107 ICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSN-WVCYLCLP 147
C C +C +C+ +G + +N W CY+C P
Sbjct: 193 CC--DFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHP 232
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 9/102 (8%)
Query: 53 CICCGSLQVHTQ------HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLL 106
C CG H Q HP + IC C ++ D DG C C G L+
Sbjct: 171 CTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLI 230
Query: 107 ICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSN-WVCYLCLP 147
C C +C +C+ +G + +N W CY+C P
Sbjct: 231 CC--DFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHP 270
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 36.2 bits (82), Expect = 0.051
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 12/62 (19%)
Query: 88 DDDGY----QSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCY 143
D DGY Q YC +C G +++C C R Y C+D + GK W C
Sbjct: 334 DGDGYETDHQDYCEVCQQGGEIILCDT--CPRAYHLVCLDPELEKAPEGK------WSCP 385
Query: 144 LC 145
C
Sbjct: 386 HC 387
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
++D + +C +C G LL C C Y C++ + +G+ W+C C
Sbjct: 411 EEDDHMEFCRVCKDGGELLCC--DACPSSYHLHCLNPPLPEIPNGE------WLCPRCTC 462
Query: 148 SSRSGLLQRRRKWR 161
G +QR WR
Sbjct: 463 PPLKGKVQRILHWR 476
>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
Length = 680
Score = 35.8 bits (81), Expect = 0.067
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 33/117 (28%)
Query: 74 APCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVD---------- 123
AP + L + D D ++ +CS+C LL+C C+R Y +C+D
Sbjct: 469 APVQPVSLPSPTSTDGDIHEDFCSVCRKSGQLLMCDT--CSRVYHLDCLDPPLKTIPKGM 526
Query: 124 ---------------SLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLK 165
++ PGT VH+ Y+ +++ Q+ KW S LK
Sbjct: 527 WICPRCQDQMLKKEEAIPWPGTLAIVHS------YIAYKAAKEEEKQKLLKWSSDLK 577
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 90 DGY----QSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145
DGY Q YC +C G +++C C R Y C+D + GK W C C
Sbjct: 372 DGYETDHQDYCEVCQQGGEIILCDT--CPRAYHLVCLDPELDRAPEGK------WSCPHC 423
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
++D + YC +C G LL C C Y C++ + +G+ W+C C
Sbjct: 451 EEDDHMEYCRVCKDGGELLCC--DACISSYHIHCLNPPLPDIPNGE------WLCPRCTC 502
Query: 148 SSRSGLLQRRRKWR 161
G +Q+ WR
Sbjct: 503 PVLKGRVQKILHWR 516
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 90 DGY----QSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145
DGY Q YC +C G +++C C R Y C+D + GK W C C
Sbjct: 372 DGYETDHQDYCEVCQQGGEIILCDT--CPRAYHLVCLDPELDRAPEGK------WSCPHC 423
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
++D + YC +C G LL C C Y C++ + +G+ W+C C
Sbjct: 451 EEDDHMEYCRVCKDGGELLCC--DACISSYHIHCLNPPLPDIPNGE------WLCPRCTC 502
Query: 148 SSRSGLLQRRRKWR 161
G +Q+ WR
Sbjct: 503 PVLKGRVQKILHWR 516
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 90 DGY----QSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145
DGY Q YC +C G +++C C R Y C+D + GK W C C
Sbjct: 431 DGYETDHQDYCEVCQQGGEIILCDT--CPRAYHLVCLDPELDRAPEGK------WSCPHC 482
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
++D + YC +C G LL C C Y C++ + +G+ W+C C
Sbjct: 510 EEDDHMEYCRVCKDGGELLCC--DACISSYHIHCLNPPLPDIPNGE------WLCPRCTC 561
Query: 148 SSRSGLLQRRRKWR 161
G +Q+ WR
Sbjct: 562 PVLKGRVQKILHWR 575
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 33.9 bits (76), Expect = 0.25
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 90 DGY----QSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145
DGY Q YC +C G +++C C R Y C+D + GK W C C
Sbjct: 363 DGYETDHQDYCEVCQQGGEIILCDT--CPRAYHMVCLDPDMEKAPEGK------WSCPHC 414
Score = 33.9 bits (76), Expect = 0.25
Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 8/74 (10%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
+DD + +C +C G LL C C Y C++ + +G+ W+C C
Sbjct: 444 EDDHHMEFCRVCKDGGELLCCDT--CPSSYHIHCLNPPLPEIPNGE------WLCPRCTC 495
Query: 148 SSRSGLLQRRRKWR 161
+ G +Q+ W+
Sbjct: 496 PALKGKVQKILIWK 509
>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
Length = 634
Score = 33.5 bits (75), Expect = 0.33
Identities = 24/101 (23%), Positives = 40/101 (39%), Gaps = 33/101 (32%)
Query: 90 DGYQSYCSICCSGETLLICGNPDCTRCYCFECVD-------------------------S 124
D ++ +CS+C LL+C C+R Y +C+D +
Sbjct: 439 DIHEDFCSVCRKSGQLLMCDT--CSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEA 496
Query: 125 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLK 165
+ PGT VH+ Y+ +++ Q+ KW S LK
Sbjct: 497 IPWPGTLAIVHS------YIAYKAAKEEEKQKLLKWSSDLK 531
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 30.4 bits (67), Expect = 2.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 8/58 (13%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145
DDD + +C++C +G LL C C + + C + SG +W+C C
Sbjct: 882 DDDPNEDWCAVCQNGGDLLCC--EKCPKVFHLTCHVPTLLSFPSG------DWICTFC 931
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 30.4 bits (67), Expect = 2.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 8/58 (13%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145
DDD + +C++C +G LL C C + + C + SG +W+C C
Sbjct: 882 DDDPNEDWCAVCQNGGDLLCC--EKCPKVFHLTCHVPTLLSFPSG------DWICTFC 931
>gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
sapiens]
Length = 687
Score = 30.4 bits (67), Expect = 2.8
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 163 QLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTS---------LGFLESGS 213
QLKAF+ RE E LE+ P W+ V SL + E S LG L SGS
Sbjct: 438 QLKAFW-REKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGS 496
Query: 214 DP 215
P
Sbjct: 497 TP 498
>gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
sapiens]
Length = 719
Score = 30.4 bits (67), Expect = 2.8
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 163 QLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTS---------LGFLESGS 213
QLKAF+ RE E LE+ P W+ V SL + E S LG L SGS
Sbjct: 438 QLKAFW-REKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGS 496
Query: 214 DP 215
P
Sbjct: 497 TP 498
>gi|116063562 FERM domain containing 4A [Homo sapiens]
Length = 1039
Score = 30.4 bits (67), Expect = 2.8
Identities = 26/104 (25%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 256 PSWYLFQFHRLLQYARPKPGSPRPFF-WMFVDNLVLNKEDLDVASRFLEMEPVTIPDV-H 313
P W + + QY PR F W ++NL ++ V VT H
Sbjct: 230 PWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGH 289
Query: 314 GGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAA 357
G AV W PA+ WA+ + L + + SK+ A
Sbjct: 290 SGI---AVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHA 330
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 30.0 bits (66), Expect = 3.7
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 18/87 (20%)
Query: 6 ALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKA-----NQRNIEDICICCGSLQ 60
A+ PE++ D+ S +S S P GR + +EV++ NQ +ED + G L
Sbjct: 31 AVKPESDQVKDL-----SSVSLSWDPSHGR-VAGFEVQSLQDAGNQLGMEDTSLSSGMLT 84
Query: 61 VHTQHPLFEG-------GICAPCKDKF 80
+T P+ EG GI P + F
Sbjct: 85 QNTNVPILEGVDVAISQGITLPSLESF 111
>gi|82830428 gon-4-like isoform b [Homo sapiens]
Length = 1529
Score = 30.0 bits (66), Expect = 3.7
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 18/87 (20%)
Query: 6 ALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKA-----NQRNIEDICICCGSLQ 60
A+ PE++ D+ S +S S P GR + +EV++ NQ +ED + G L
Sbjct: 31 AVKPESDQVKDL-----SSVSLSWDPSHGR-VAGFEVQSLQDAGNQLGMEDTSLSSGMLT 84
Query: 61 VHTQHPLFEG-------GICAPCKDKF 80
+T P+ EG GI P + F
Sbjct: 85 QNTNVPILEGVDVAISQGITLPSLESF 111
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/63 (25%), Positives = 28/63 (44%), Gaps = 8/63 (12%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
+DD + +C++C +G LL C C + + C + SG+ W+C C
Sbjct: 821 EDDPNEDWCAVCQNGGELLCC--EKCPKVFHLSCHVPTLTNFPSGE------WICTFCRD 872
Query: 148 SSR 150
S+
Sbjct: 873 LSK 875
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/63 (25%), Positives = 28/63 (44%), Gaps = 8/63 (12%)
Query: 88 DDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLP 147
+DD + +C++C +G LL C C + + C + SG+ W+C C
Sbjct: 787 EDDPNEDWCAVCQNGGELLCC--EKCPKVFHLSCHVPTLTNFPSGE------WICTFCRD 838
Query: 148 SSR 150
S+
Sbjct: 839 LSK 841
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 29.6 bits (65), Expect = 4.8
Identities = 10/32 (31%), Positives = 17/32 (53%)
Query: 92 YQSYCSICCSGETLLICGNPDCTRCYCFECVD 123
++ YC C G L++C DC + Y C++
Sbjct: 1320 HEDYCFQCGDGGELVMCDKKDCPKAYHLLCLN 1351
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 29.3 bits (64), Expect = 6.3
Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 12/55 (21%)
Query: 93 QSYCSICCSGETLLICGNPDCTRCYCFEC-VDSLVG-PGTSGKVHAMSNWVCYLC 145
+ +C++C +G LL C C + + C V +L+ PG WVC LC
Sbjct: 970 EDFCAVCLNGGELLCCDR--CPKVFHLSCHVPALLSFPG--------GEWVCTLC 1014
>gi|149773468 RAD51 associated protein 2 [Homo sapiens]
Length = 1159
Score = 29.3 bits (64), Expect = 6.3
Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 311 DVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWPTKL---VKNC 367
+ H S+ + W+ + I + + L+ +EE+ + A++ +S K TK+ K+
Sbjct: 805 ETHTTSITQVLNFWNLLSEIEEKKYDLILKEEVKVTAESLTNSCQVHK-DTKIEKEEKDS 863
Query: 368 FLPLREYFKYFSTELTS 384
F P+ + F S L S
Sbjct: 864 FFPMDDMFSVQSVSLIS 880
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,963,036
Number of Sequences: 37866
Number of extensions: 850845
Number of successful extensions: 1776
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1725
Number of HSP's gapped (non-prelim): 47
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.