Guide to the Human Genome
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Name: DNMT3A Sequence: fasta or formatted (723aa) NCBI GI: 77176455
Description:

DNA cytosine methyltransferase 3 alpha isoform b

Referenced in:

DNA Methylation

Other entries for this name:
alt prot [912aa] DNA cytosine methyltransferase 3 alpha isoform a
alt prot [912aa] DNA cytosine methyltransferase 3 alpha isoform a
alt prot [166aa] DNA cytosine methyltransferase 3 alpha isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         48           3
 C cysteine            3.7         27           2
 D aspartate           5.7         41           3
 E glutamate           7.9         57           3
 F phenylalanine       4.3         31           2
 G glycine             7.7         56           2
 H histidine           1.8         13           1
 I isoleucine          4.0         29           2
 K lysine              6.2         45           2
 L leucine             6.4         46           2
 M methionine          2.8         20           1
 N asparagine          3.7         27           3
 P proline             6.6         48           4
 Q glutamine           3.3         24           2
 R arginine            6.8         49           3
 S serine              5.5         40           2
 T threonine           3.6         26           2
 V valine              8.0         58           2
 W tryptophan          2.2         16           2
 Y tyrosine            3.0         22           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA cytosine methyltransferase 3 alpha isoform b [Ho... 
DNMT3A                0.968   DNA cytosine methyltransferase 3 alpha isoform a [Ho...
DNMT3A                0.968   DNA cytosine methyltransferase 3 alpha isoform a [Ho...
DNMT3B                0.539   DNA cytosine-5 methyltransferase 3 beta isoform 6 [H...
DNMT3B                0.539   DNA cytosine-5 methyltransferase 3 beta isoform 2 [H...
DNMT3B                0.535   DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho...
DNMT3B                0.418   DNA cytosine-5 methyltransferase 3 beta isoform 3 [H...
DNMT3L                0.153   cytosine-5-methyltransferase 3-like protein isoform ...
DNMT3L                0.153   cytosine-5-methyltransferase 3-like protein isoform ...
PWWP2B                0.027   PWWP domain containing 2 isoform 1 
PWWP2A                0.021   PWWP domain containing 2A isoform b 
ATRX                  0.014   transcriptional regulator ATRX isoform 1 
ATRX                  0.013   transcriptional regulator ATRX isoform 2 
HDGFL1                0.011   hepatoma derived growth factor-like 1 
N-PAC                 0.011   cytokine-like nuclear factor n-pac 
MBD5                  0.009   methyl-CpG binding domain protein 5 
CHD5                  0.009   chromodomain helicase DNA binding protein 5 
WHSC1L1               0.009   WHSC1L1 protein isoform long 
WHSC1L1               0.009   WHSC1L1 protein isoform short 
CHD4                  0.007   chromodomain helicase DNA binding protein 4 
CHD3                  0.007   chromodomain helicase DNA binding protein 3 isoform ...
CHD3                  0.007   chromodomain helicase DNA binding protein 3 isoform ...
CHD3                  0.007   chromodomain helicase DNA binding protein 3 isoform...
ZC3H4                 0.007   zinc finger CCCH-type containing 4 
MSH6                  0.007   mutS homolog 6 
ZBTB45                0.006   zinc finger and BTB domain containing 45 
SCAF1                 0.006   SR-related CTD-associated factor 1 
MXRA7                 0.006   transmembrane anchor protein 1 isoform 3 
MXRA7                 0.006   transmembrane anchor protein 1 isoform 2 
MXRA7                 0.006   transmembrane anchor protein 1 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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