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Search of human proteins with 28557677
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28557677 PHD finger protein 6 isoform 1 [Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28557677 PHD finger protein 6 isoform 1 [Homo sapiens] 762 0.0
gi|62865858 PHD finger protein 6 isoform 1 [Homo sapiens] 762 0.0
gi|63478060 PHD finger protein 6 isoform 2 [Homo sapiens] 577 e-165
gi|94681065 PHD finger protein 11 isoform a [Homo sapiens] 103 3e-22
gi|94681069 PHD finger protein 11 isoform b [Homo sapiens] 102 4e-22
gi|33620749 G2/M-phase specific E3 ubiquitin ligase [Homo sapiens] 83 4e-16
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 68 1e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 64 2e-10
gi|21361543 PHD finger protein 7 isoform 1 [Homo sapiens] 64 2e-10
gi|27894287 PHD finger protein 7 isoform 2 [Homo sapiens] 64 2e-10
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 52 8e-07
gi|40807477 retinoic acid induced 1 [Homo sapiens] 52 8e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 1e-06
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 49 9e-06
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 49 9e-06
gi|117190334 PHD finger protein 16 [Homo sapiens] 42 9e-04
gi|7662006 PHD finger protein 16 [Homo sapiens] 42 9e-04
gi|40556370 PHD finger protein 15 [Homo sapiens] 41 0.001
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 38 0.012
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 38 0.012
gi|56090620 NFKB activating protein-like [Homo sapiens] 37 0.021
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 37 0.028
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 37 0.028
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 37 0.028
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 37 0.028
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 37 0.028
gi|238814389 zinc finger, MYND domain containing 11 isoform a [H... 36 0.047
gi|238814387 zinc finger, MYND domain containing 11 isoform b [H... 36 0.047
gi|238814385 zinc finger, MYND domain containing 11 isoform a [H... 36 0.047
gi|168229156 NFKB activating protein [Homo sapiens] 36 0.062
>gi|28557677 PHD finger protein 6 isoform 1 [Homo sapiens]
Length = 365
Score = 762 bits (1968), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE
Sbjct: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
Query: 61 SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS 120
SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS
Sbjct: 61 SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS 120
Query: 121 QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR 180
QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR
Sbjct: 121 QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR 180
Query: 181 STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY 240
STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY
Sbjct: 181 STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY 240
Query: 241 KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 300
KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT
Sbjct: 241 KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 300
Query: 301 YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ 360
YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ
Sbjct: 301 YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ 360
Query: 361 QLNGN 365
QLNGN
Sbjct: 361 QLNGN 365
>gi|62865858 PHD finger protein 6 isoform 1 [Homo sapiens]
Length = 365
Score = 762 bits (1968), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE
Sbjct: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
Query: 61 SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS 120
SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS
Sbjct: 61 SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS 120
Query: 121 QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR 180
QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR
Sbjct: 121 QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR 180
Query: 181 STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY 240
STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY
Sbjct: 181 STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY 240
Query: 241 KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 300
KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT
Sbjct: 241 KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 300
Query: 301 YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ 360
YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ
Sbjct: 301 YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ 360
Query: 361 QLNGN 365
QLNGN
Sbjct: 361 QLNGN 365
>gi|63478060 PHD finger protein 6 isoform 2 [Homo sapiens]
Length = 312
Score = 577 bits (1487), Expect = e-165
Identities = 279/282 (98%), Positives = 280/282 (99%), Gaps = 1/282 (0%)
Query: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE
Sbjct: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
Query: 61 SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS 120
SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS
Sbjct: 61 SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS 120
Query: 121 QGIYMVYCRKHKKTAHNSE-ADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDT 179
QGIYMVYCRKHKKTAHNSE ADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDT
Sbjct: 121 QGIYMVYCRKHKKTAHNSEAADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDT 180
Query: 180 RSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAH 239
RSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAH
Sbjct: 181 RSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAH 240
Query: 240 YKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCT 281
YKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRM C+
Sbjct: 241 YKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMVCS 282
Score = 128 bits (321), Expect = 9e-30
Identities = 67/162 (41%), Positives = 93/162 (57%), Gaps = 9/162 (5%)
Query: 190 MESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGT 249
M SS + + P R KCGFC ++ G+L I +K AAH+KCMLFSS
Sbjct: 1 MSSSVEQKKGPTRQR------KCGFCKSNRDKE--CGQLLISENQKVAAHHKCMLFSSAL 52
Query: 250 VQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQD 309
V + + G F I+ V +EIKRG ++ C+LC PGATIGC++K C +TYHYHC + D
Sbjct: 53 VS-SHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHD 111
Query: 310 KAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVE 351
KA+ E S+GIY +YC+ H E + ES + ++E
Sbjct: 112 KAQIREKPSQGIYMVYCRKHKKTAHNSEAADLEESFNEHELE 153
Score = 60.5 bits (145), Expect = 2e-09
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Query: 1 MSSSVEQKKGPTRQR------KCGFCKSNRDKE--CGQLLISENQKVAAHHKCMLFSSAL 52
M SS + + P R KCGFC ++ G+L I +K AAH+KCMLFSS
Sbjct: 191 MESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGT 250
Query: 53 VS-SHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHC 87
V + + G F I+ V +EIKRG +++CS C
Sbjct: 251 VQLTTTSRAEFGDFDIKTVLQEIKRGKRMVCSFYIC 286
>gi|94681065 PHD finger protein 11 isoform a [Homo sapiens]
Length = 331
Score = 103 bits (256), Expect = 3e-22
Identities = 51/134 (38%), Positives = 76/134 (56%), Gaps = 6/134 (4%)
Query: 1 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE 60
+ + V Q +R C C +D E L ++++ +AAH C+L+SS LV D +
Sbjct: 29 LPTGVFQVAEKMEKRTCALCP--KDVEYNVLYFAQSENIAAHENCLLYSSGLVECE-DQD 85
Query: 61 SLG---GFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIRE 117
L F +E V+KEI+RG KL C CH GAT+GCD+K C++ YH+ CA D A +
Sbjct: 86 PLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQS 145
Query: 118 KPSQGIYMVYCRKH 131
+GIY + C++H
Sbjct: 146 DGVRGIYKLLCQQH 159
Score = 90.9 bits (224), Expect = 2e-18
Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 5/120 (4%)
Query: 212 CGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFG-DFDIKTVLQ 270
C C E N L+ ++ AAH C+L+SSG V+ FD+++V +
Sbjct: 45 CALCPKDVEYNV----LYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKK 100
Query: 271 EIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHS 330
EI+RG+++KC C + GAT+GC++K C K YH+ C +D A + RGIYKL C+ H+
Sbjct: 101 EIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHA 160
>gi|94681069 PHD finger protein 11 isoform b [Homo sapiens]
Length = 292
Score = 102 bits (255), Expect = 4e-22
Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 6/121 (4%)
Query: 14 QRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLG---GFSIEDV 70
+R C C +D E L ++++ +AAH C+L+SS LV D + L F +E V
Sbjct: 3 KRTCALCP--KDVEYNVLYFAQSENIAAHENCLLYSSGLVECE-DQDPLNPDRSFDVESV 59
Query: 71 QKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRK 130
+KEI+RG KL C CH GAT+GCD+K C++ YH+ CA D A + +GIY + C++
Sbjct: 60 KKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQ 119
Query: 131 H 131
H
Sbjct: 120 H 120
Score = 90.9 bits (224), Expect = 2e-18
Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 5/120 (4%)
Query: 212 CGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFG-DFDIKTVLQ 270
C C E N L+ ++ AAH C+L+SSG V+ FD+++V +
Sbjct: 6 CALCPKDVEYNV----LYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKK 61
Query: 271 EIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHS 330
EI+RG+++KC C + GAT+GC++K C K YH+ C +D A + RGIYKL C+ H+
Sbjct: 62 EIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHA 121
>gi|33620749 G2/M-phase specific E3 ubiquitin ligase [Homo sapiens]
Length = 706
Score = 82.8 bits (203), Expect = 4e-16
Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 6 EQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLG 63
E K G ++ C FC+ + D + G+ E + H+ C+L SS + + E +
Sbjct: 3 ESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVY 62
Query: 64 GFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGI 123
GF IED++KE+ R +KL C +C GA+IGC C R+YH+ C L + + G
Sbjct: 63 GFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ---FTGN 119
Query: 124 YMVYCRKHK 132
+ +C H+
Sbjct: 120 FASFCWDHR 128
Score = 68.6 bits (166), Expect = 9e-12
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 5/130 (3%)
Query: 201 HRSSPSDTRP-KCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAE 259
+ S P D++ C FC ++ G+ HY C+L SSG Q
Sbjct: 2 NESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGV 61
Query: 260 FGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSR 319
+G F I+ + +E+ R ++KC +C + GA+IGC C ++YH+ CG+Q + +
Sbjct: 62 YG-FLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIF---QFT 117
Query: 320 GIYKLYCKNH 329
G + +C +H
Sbjct: 118 GNFASFCWDH 127
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 67.8 bits (164), Expect = 1e-11
Identities = 53/199 (26%), Positives = 83/199 (41%), Gaps = 26/199 (13%)
Query: 136 HNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSY 195
HN E N H +P P KK +P KG E T H S+
Sbjct: 1800 HNYAQWQEREENSHTEQP--PLMKKIIPAPKP-----KGPGEPDSPTPLHPPTPPILSTD 1852
Query: 196 RDR--SPHRSSPS--DTRPKCGFCHV-GEEENEARGKLHIFNAKKAAAHYKCMLFSSGTV 250
R R SP + P + +C C G++ G+L ++ + H C L+S+
Sbjct: 1853 RSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRL-LYIGQNEWTHVNCALWSAEVF 1911
Query: 251 QLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDK 310
E D +K V + RGK+++C C +PGAT+GC + +C YH+ C
Sbjct: 1912 --------EDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKN 1963
Query: 311 AKYIENMSRGIYKLYCKNH 329
++++ K+YC+ H
Sbjct: 1964 CVFLDDK-----KVYCQRH 1977
Score = 56.2 bits (134), Expect = 4e-08
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 18/135 (13%)
Query: 2 SSSVEQKKGPTRQRKCGFCKSNRD---KECGQLL-ISENQKVAAHHKCMLFSSALVSSHS 57
S + G R+C C + D + G+LL I +N+ H C L+S+ +
Sbjct: 1858 SPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWT--HVNCALWSAEVFEDDD 1915
Query: 58 DNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIRE 117
S+++V + RG +L C C PGAT+GC + +C YH+ C+ +
Sbjct: 1916 G-------SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLD 1968
Query: 118 KPSQGIYMVYCRKHK 132
VYC++H+
Sbjct: 1969 DKK-----VYCQRHR 1978
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 64.3 bits (155), Expect = 2e-10
Identities = 35/140 (25%), Positives = 72/140 (51%), Gaps = 15/140 (10%)
Query: 192 SSSYRDRSPHRSSPSDTRPKCGFC-HVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTV 250
S++++ + P S + +C C G+ +++ G+L ++ + H C ++S+
Sbjct: 1561 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRL-LYIGQNEWTHVNCAIWSAEVF 1619
Query: 251 QLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDK 310
E D +K V + RG++M+C LC +PGAT+GC + +C+ +H+ C +
Sbjct: 1620 --------EENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCA---R 1668
Query: 311 AKYIENMSRGIYKLYCKNHS 330
A Y + + K++C+ H+
Sbjct: 1669 ASYC--IFQDDKKVFCQKHT 1686
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 18/137 (13%)
Query: 15 RKCGFCKSNRD---KECGQLL-ISENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDV 70
R+C C D KE G+LL I +N+ H C ++S+ + + S+++V
Sbjct: 1579 RQCALCLKYGDADSKEAGRLLYIGQNEWT--HVNCAIWSAEVFEENDG-------SLKNV 1629
Query: 71 QKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRK 130
+ RG ++ C LC PGAT+GC + +C +H+ CA ++ V+C+K
Sbjct: 1630 HAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKK-----VFCQK 1684
Query: 131 HKKTAHNSEADLEESFN 147
H E + F+
Sbjct: 1685 HTDLLDGKEIVNPDGFD 1701
>gi|21361543 PHD finger protein 7 isoform 1 [Homo sapiens]
Length = 381
Score = 63.9 bits (154), Expect = 2e-10
Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 12/134 (8%)
Query: 5 VEQKKGPTRQRKCGFC--KSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESL 62
V Q+K P+ C C + ++ G+ L +N ++ H+ C++ SS L N
Sbjct: 22 VTQRK-PSSGPVCWLCLREPGDPEKLGEFLQKDN--ISVHYFCLILSSKLPQRGQSNRGF 78
Query: 63 GGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQ- 121
GF ED++KE R ++ +C +C GA I C C R +H C Q R SQ
Sbjct: 79 HGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPC-----GQERGCLSQF 133
Query: 122 -GIYMVYCRKHKKT 134
G Y +C KH+ T
Sbjct: 134 FGEYKSFCDKHRPT 147
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 7/136 (5%)
Query: 194 SYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLT 253
S + R + PS + P C C + E G+ + HY C++ SS Q
Sbjct: 16 SAKTRRVTQRKPS-SGPVCWLCLREPGDPEKLGEF--LQKDNISVHYFCLILSSKLPQRG 72
Query: 254 TTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKY 313
++R F F + + +E R R C +C + GA I C+ C++ +H CG + +
Sbjct: 73 QSNRG-FHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCG---QERG 128
Query: 314 IENMSRGIYKLYCKNH 329
+ G YK +C H
Sbjct: 129 CLSQFFGEYKSFCDKH 144
>gi|27894287 PHD finger protein 7 isoform 2 [Homo sapiens]
Length = 342
Score = 63.9 bits (154), Expect = 2e-10
Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 12/134 (8%)
Query: 5 VEQKKGPTRQRKCGFC--KSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESL 62
V Q+K P+ C C + ++ G+ L +N ++ H+ C++ SS L N
Sbjct: 22 VTQRK-PSSGPVCWLCLREPGDPEKLGEFLQKDN--ISVHYFCLILSSKLPQRGQSNRGF 78
Query: 63 GGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQ- 121
GF ED++KE R ++ +C +C GA I C C R +H C Q R SQ
Sbjct: 79 HGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPC-----GQERGCLSQF 133
Query: 122 -GIYMVYCRKHKKT 134
G Y +C KH+ T
Sbjct: 134 FGEYKSFCDKHRPT 147
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 7/136 (5%)
Query: 194 SYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLT 253
S + R + PS + P C C + E G+ + HY C++ SS Q
Sbjct: 16 SAKTRRVTQRKPS-SGPVCWLCLREPGDPEKLGEF--LQKDNISVHYFCLILSSKLPQRG 72
Query: 254 TTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKY 313
++R F F + + +E R R C +C + GA I C+ C++ +H CG + +
Sbjct: 73 QSNRG-FHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCG---QERG 128
Query: 314 IENMSRGIYKLYCKNH 329
+ G YK +C H
Sbjct: 129 CLSQFFGEYKSFCDKH 144
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 52.0 bits (123), Expect = 8e-07
Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Query: 1 MSSSVEQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSD 58
+ +S++ P RKC FC D + L++ + + H C L+S+ + + +
Sbjct: 4386 LGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAG 4445
Query: 59 NESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQ 114
++ +V+ ++RG ++ C CH GAT GC C YH+ CA+ KAQ
Sbjct: 4446 -------ALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAI--KAQ 4492
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 16/135 (11%)
Query: 205 PSDTRPKCGFCHVGEEENEARGKLHIFNAKKAA-AHYKCMLFSSGTVQLTTTSRAEFGDF 263
P D R KC FCH E + G + N H C L+S+ + +
Sbjct: 4396 PKDYR-KCCFCHE-EGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGA------- 4446
Query: 264 DIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYK 323
+ V ++RG +MKC C + GAT GC C YH+ C ++ + + ++ +
Sbjct: 4447 -LINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT----- 4500
Query: 324 LYCKNHSGNDERDEE 338
+ C H ++E
Sbjct: 4501 MLCPMHKPKGIHEQE 4515
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 30 QLLISENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPG 89
Q L AHH+C+ +S + + +V K + G+ C+ C G
Sbjct: 240 QALFDSTGTCWAHHRCVEWSLGVCQMEEP-------LLVNVDKAVVSGSTERCAFCKHLG 292
Query: 90 ATIGCDVKTCHRTYHYHCA 108
ATI C + C + YHY CA
Sbjct: 293 ATIKCCEEKCTQMYHYPCA 311
Score = 39.7 bits (91), Expect = 0.004
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Query: 238 AHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKAC 297
AH++C+ +S G Q+ + V + + G +C C GATI C + C
Sbjct: 251 AHHRCVEWSLGVCQMEEPL--------LVNVDKAVVSGSTERCAFCKHLGATIKCCEEKC 302
Query: 298 VKTYHYHC 305
+ YHY C
Sbjct: 303 TQMYHYPC 310
>gi|40807477 retinoic acid induced 1 [Homo sapiens]
Length = 1906
Score = 52.0 bits (123), Expect = 8e-07
Identities = 66/258 (25%), Positives = 95/258 (36%), Gaps = 48/258 (18%)
Query: 80 LMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSE 139
L+C LC P A C Y HC K +++EK + + T +
Sbjct: 1685 LVCCLCQNP-ANFKDLGDLCGPYYPEHCLPKKKPKLKEKV----------RPEGTCEEAS 1733
Query: 140 ADLEESFNEHEL-------EPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMES 192
LE + E +P P K P +T+ +GLS R S + D E
Sbjct: 1734 LPLERTLKGPECAAAATAGKPPRPDGPADPAKQGPLRTSARGLSR--RLQSCYCCDGRED 1791
Query: 193 SSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQL 252
++P+D K H +E A A++ H C +++ G +
Sbjct: 1792 GG------EEAAPADKGRK----HECSKEAPAEPG---GEAQEHWVHEACAVWTGGVYLV 1838
Query: 253 TTTSRAEFGDFDIKTVLQE-IKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKA 311
FG LQE +K M C+ C + GATIGC K C+ TYHY C
Sbjct: 1839 AGKL---FG-------LQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCASDAGC 1888
Query: 312 KYIENMSRGIYKLYCKNH 329
+IE + L C H
Sbjct: 1889 IFIEEN----FSLKCPKH 1902
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
Query: 70 VQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCR 129
+Q+ +K +MCS C GATIGC K C TYHY CA E+ + + C
Sbjct: 1845 LQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCASDAGCIFIEEN----FSLKCP 1900
Query: 130 KHKK 133
KHK+
Sbjct: 1901 KHKR 1904
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 1 MSSSVEQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSD 58
+ +++ K P R+C FC D + L++ + + H C L+S+ +
Sbjct: 5016 LGTALRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVY----- 5070
Query: 59 NESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDK 112
E+ GG ++ +V+ + RG CSLC GAT C+ C YH+ CA+ K
Sbjct: 5071 -ETQGG-ALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAK 5122
Score = 47.0 bits (110), Expect = 3e-05
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 205 PSDTRPKCGFCHVGEEENEARGKLHIFNAKKAA-AHYKCMLFSSGTVQLTTTSRAEFGDF 263
P D R +C FCH E + G + N H C L+S+ + +
Sbjct: 5026 PRDMR-RCCFCHE-EGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGA------- 5076
Query: 264 DIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIEN 316
+ V + RG KC+LC + GAT C C YH+ C ++ K + ++
Sbjct: 5077 -LMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKD 5128
Score = 38.9 bits (89), Expect = 0.007
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 15/105 (14%)
Query: 41 AHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCH 100
AHH C +S+ + G + V K I G CS C GA+I C C
Sbjct: 138 AHHWCAAWSAGVWGQE-------GPELCGVDKAIFSGISQRCSHCTRLGASIPCRSPGCP 190
Query: 101 RTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEES 145
R YH+ CA + + K Q + C +H + A A LEE+
Sbjct: 191 RLYHFPCATASGSFLSMKTLQ----LLCPEHSEGA----AYLEEA 227
Score = 33.9 bits (76), Expect = 0.24
Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 275 GKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHS 330
G +C+ C++ GA+I C C + YH+ C + +S +L C HS
Sbjct: 167 GISQRCSHCTRLGASIPCRSPGCPRLYHFPCATASGS----FLSMKTLQLLCPEHS 218
>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
Length = 1938
Score = 48.5 bits (114), Expect = 9e-06
Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 16/190 (8%)
Query: 130 KHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDE 189
+HK ++ S+ D EE E E + +++S PR + SED +
Sbjct: 1752 RHKSASNGSKTDTEE-----EEEQQQQQKEQRSLAAHPRFKR-RHRSEDCGGGPRSLSRG 1805
Query: 190 MESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGT 249
+ + D++P G E E + ++ + H C+L+++G
Sbjct: 1806 LPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCILWANGI 1865
Query: 250 VQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQ- 308
+ + + + ++ + MKC+ C + GAT+GC K C YHY C +
Sbjct: 1866 YLVCGR---------LYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDA 1916
Query: 309 DKAKYIENMS 318
D + EN S
Sbjct: 1917 DCLLHEENFS 1926
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 70 VQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCR 129
+Q+ ++ ++ CS C GAT+GC K C YHY CA+ + E+ + V C
Sbjct: 1875 LQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEEN----FSVRCP 1930
Query: 130 KHK 132
KHK
Sbjct: 1931 KHK 1933
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 48.5 bits (114), Expect = 9e-06
Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 16/190 (8%)
Query: 130 KHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDE 189
+HK ++ S+ D EE E E + +++S PR + SED +
Sbjct: 1752 RHKSASNGSKTDTEE-----EEEQQQQQKEQRSLAAHPRFKR-RHRSEDCGGGPRSLSRG 1805
Query: 190 MESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGT 249
+ + D++P G E E + ++ + H C+L+++G
Sbjct: 1806 LPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCILWANGI 1865
Query: 250 VQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQ- 308
+ + + + ++ + MKC+ C + GAT+GC K C YHY C +
Sbjct: 1866 YLVCGR---------LYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDA 1916
Query: 309 DKAKYIENMS 318
D + EN S
Sbjct: 1917 DCLLHEENFS 1926
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 70 VQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCR 129
+Q+ ++ ++ CS C GAT+GC K C YHY CA+ + E+ + V C
Sbjct: 1875 LQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEEN----FSVRCP 1930
Query: 130 KHK 132
KHK
Sbjct: 1931 KHK 1933
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 42.0 bits (97), Expect = 9e-04
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 280 CTLCS-QPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRG---IYKLYCKNHSGNDER 335
C LC + GA I C IK+C+ +H C + + + G +K YC HS N ++
Sbjct: 312 CNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQK 371
Query: 336 --DEEDEERESKSRGKVEIDQQQLTQQQL 362
+ E +K + + + ++ L Q+L
Sbjct: 372 LGEAEYPHHRAKEQSQAKSEKTSLRAQKL 400
Score = 41.2 bits (95), Expect = 0.001
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 80 LMCSLCHCP-GATIGCDVKTCHRTYHYHCALHDKAQIREKPSQG---IYMVYCRKHKKTA 135
L+C+LC GA I C +K+C +H CA +++ +G + YC KH +
Sbjct: 310 LVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNR 369
Query: 136 HN-SEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGL 175
EA+ + + + S K+ +++K R + F L
Sbjct: 370 QKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSL 410
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 42.0 bits (97), Expect = 9e-04
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 280 CTLCS-QPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRG---IYKLYCKNHSGNDER 335
C LC + GA I C IK+C+ +H C + + + G +K YC HS N ++
Sbjct: 312 CNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQK 371
Query: 336 --DEEDEERESKSRGKVEIDQQQLTQQQL 362
+ E +K + + + ++ L Q+L
Sbjct: 372 LGEAEYPHHRAKEQSQAKSEKTSLRAQKL 400
Score = 41.2 bits (95), Expect = 0.001
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 80 LMCSLCHCP-GATIGCDVKTCHRTYHYHCALHDKAQIREKPSQG---IYMVYCRKHKKTA 135
L+C+LC GA I C +K+C +H CA +++ +G + YC KH +
Sbjct: 310 LVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNR 369
Query: 136 HN-SEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGL 175
EA+ + + + S K+ +++K R + F L
Sbjct: 370 QKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYSL 410
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 278 MKCTLCSQ-PGATIGCEIKACVKTYHYHC----GVQDKAKYIENMSRGIYKLYCKNHSGN 332
+ C+LC + G I C + +CV +H C G++ + +N +K +C+ HS
Sbjct: 309 LSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADN-DEVKFKSFCQEHSDG 367
Query: 333 DERDEEDEERESKSRGKVEIDQQQLTQQQL 362
R+E E S+ ++++ L +Q+L
Sbjct: 368 GPRNEPTSEPTEPSQAGEDLEKVTLRKQRL 397
Score = 35.0 bits (79), Expect = 0.11
Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 14/104 (13%)
Query: 80 LMCSLC-HCPGATIGCDVKTCHRTYHYHCALHDKAQIR---EKPSQGIYMVYCRKHKKTA 135
L CSLC C G I C + +C +H CA ++R + + +C++H
Sbjct: 309 LSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEHSDGG 368
Query: 136 HNSEADLEESFNEHELEPSSP-KSKKKSRKGRPRKTNFKGLSED 178
NE EP+ P ++ + K RK + L ED
Sbjct: 369 PR---------NEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEED 403
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 38.1 bits (87), Expect = 0.012
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 280 CTLCSQP-GATIGCEIKACVKTYHYHC----GVQDKAKYIENMSRGIYKLYCKNHSGNDE 334
C+LC++ GA+I C +K C +H C G++ K EN +K YC HS + +
Sbjct: 315 CSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAEN-DEVKFKSYCPKHSSHRK 373
Query: 335 RDEEDEERESKSRGKVE 351
+E + ++ G E
Sbjct: 374 PEESLGKGAAQENGAPE 390
Score = 37.7 bits (86), Expect = 0.016
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 80 LMCSLCHCP-GATIGCDVKTCHRTYHYHCALH---DKAQIREKPSQGIYMVYCRKHKKTA 135
L+CSLC+ GA+I C VK C +H CA + I + + + YC KH
Sbjct: 313 LVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHR 372
Query: 136 HNSEADLEESFNEHELEPSSPKS 158
E+ + + E+ SP++
Sbjct: 373 KPEESLGKGAAQENGAPECSPRN 395
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 38.1 bits (87), Expect = 0.012
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 280 CTLCSQP-GATIGCEIKACVKTYHYHC----GVQDKAKYIENMSRGIYKLYCKNHSGNDE 334
C+LC++ GA+I C +K C +H C G++ K EN +K YC HS + +
Sbjct: 315 CSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAEN-DEVKFKSYCPKHSSHRK 373
Query: 335 RDEEDEERESKSRGKVE 351
+E + ++ G E
Sbjct: 374 PEESLGKGAAQENGAPE 390
Score = 37.7 bits (86), Expect = 0.016
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 80 LMCSLCHCP-GATIGCDVKTCHRTYHYHCALH---DKAQIREKPSQGIYMVYCRKHKKTA 135
L+CSLC+ GA+I C VK C +H CA + I + + + YC KH
Sbjct: 313 LVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHR 372
Query: 136 HNSEADLEESFNEHELEPSSPKS 158
E+ + + E+ SP++
Sbjct: 373 KPEESLGKGAAQENGAPECSPRN 395
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 37.4 bits (85), Expect = 0.021
Identities = 34/199 (17%), Positives = 79/199 (39%), Gaps = 7/199 (3%)
Query: 129 RKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTD 188
RK+ + NSE+D ++ + + K KKK + +K N K E + S+ +
Sbjct: 199 RKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
Query: 189 EMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEAR-GKLHIFNAKKAAAHY---KCML 244
++ +++ ++ + P+ H ++E + G + A A Y +
Sbjct: 259 DLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKRI 318
Query: 245 FSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYH 304
G + LT+ E G F+ + R +RM+ + + K + +++
Sbjct: 319 PRRGEIGLTS---EEIGSFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQE 375
Query: 305 CGVQDKAKYIENMSRGIYK 323
+ ++K + + ++K
Sbjct: 376 ERRKRESKILASFREMVHK 394
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.028
Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 32/133 (24%)
Query: 73 EIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDK------------AQIREKPS 120
E KR ++ C C G + CD K C + YH C K + KPS
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPS 1292
Query: 121 QGIYMV----YCRKHKK-TAHNSEADLEESFNEHEL---------------EPSSPKSKK 160
+ +C++H+ TA + D EH+L EP PK K+
Sbjct: 1293 TSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKR 1352
Query: 161 KSRKGRPRKTNFK 173
+ R+G R T K
Sbjct: 1353 RRRRGWRRVTEGK 1365
Score = 31.2 bits (69), Expect = 1.5
Identities = 13/35 (37%), Positives = 16/35 (45%)
Query: 271 EIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHC 305
E KR +C C G + C+ K C K YH C
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSC 1267
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.028
Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 32/133 (24%)
Query: 73 EIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDK------------AQIREKPS 120
E KR ++ C C G + CD K C + YH C K + KPS
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPS 1292
Query: 121 QGIYMV----YCRKHKK-TAHNSEADLEESFNEHEL---------------EPSSPKSKK 160
+ +C++H+ TA + D EH+L EP PK K+
Sbjct: 1293 TSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKR 1352
Query: 161 KSRKGRPRKTNFK 173
+ R+G R T K
Sbjct: 1353 RRRRGWRRVTEGK 1365
Score = 31.2 bits (69), Expect = 1.5
Identities = 13/35 (37%), Positives = 16/35 (45%)
Query: 271 EIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHC 305
E KR +C C G + C+ K C K YH C
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSC 1267
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.028
Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 32/133 (24%)
Query: 73 EIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDK------------AQIREKPS 120
E KR ++ C C G + CD K C + YH C K + KPS
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPS 1292
Query: 121 QGIYMV----YCRKHKK-TAHNSEADLEESFNEHEL---------------EPSSPKSKK 160
+ +C++H+ TA + D EH+L EP PK K+
Sbjct: 1293 TSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKR 1352
Query: 161 KSRKGRPRKTNFK 173
+ R+G R T K
Sbjct: 1353 RRRRGWRRVTEGK 1365
Score = 31.2 bits (69), Expect = 1.5
Identities = 13/35 (37%), Positives = 16/35 (45%)
Query: 271 EIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHC 305
E KR +C C G + C+ K C K YH C
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSC 1267
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.028
Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 32/133 (24%)
Query: 73 EIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDK------------AQIREKPS 120
E KR ++ C C G + CD K C + YH C K + KPS
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPS 1292
Query: 121 QGIYMV----YCRKHKK-TAHNSEADLEESFNEHEL---------------EPSSPKSKK 160
+ +C++H+ TA + D EH+L EP PK K+
Sbjct: 1293 TSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKR 1352
Query: 161 KSRKGRPRKTNFK 173
+ R+G R T K
Sbjct: 1353 RRRRGWRRVTEGK 1365
Score = 31.2 bits (69), Expect = 1.5
Identities = 13/35 (37%), Positives = 16/35 (45%)
Query: 271 EIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHC 305
E KR +C C G + C+ K C K YH C
Sbjct: 1233 EGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSC 1267
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 37.0 bits (84), Expect = 0.028
Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 12/107 (11%)
Query: 130 KHKKTAHNSEADLEESFNEH---ELEPSSPK--------SKKKSRKGRPRKTNFKGLSED 178
++KKT + A+ EE NE+ ELE S K SKK+ RK + +K + + S
Sbjct: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSS 108
Query: 179 TRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEAR 225
+ S SS + + E + + R + K E E+E++
Sbjct: 109 SSSDSSSSSSDSEDEE-KKQGKRRKKKKNRSYKSSQSSTHESESESK 154
>gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo
sapiens]
Length = 602
Score = 36.2 bits (82), Expect = 0.047
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 82 CSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSE 139
C CH PG + CD+ C R YH C L D+ ++R+ S V CR KK N +
Sbjct: 103 CFECHLPGEVLICDL--CFRVYHSKC-LSDEFRLRDSSSPWQCPV-CRSIKKKNTNKQ 156
>gi|238814387 zinc finger, MYND domain containing 11 isoform b [Homo
sapiens]
Length = 567
Score = 36.2 bits (82), Expect = 0.047
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 82 CSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSE 139
C CH PG + CD+ C R YH C L D+ ++R+ S V CR KK N +
Sbjct: 103 CFECHLPGEVLICDL--CFRVYHSKC-LSDEFRLRDSSSPWQCPV-CRSIKKKNTNKQ 156
>gi|238814385 zinc finger, MYND domain containing 11 isoform a [Homo
sapiens]
Length = 602
Score = 36.2 bits (82), Expect = 0.047
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 82 CSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSE 139
C CH PG + CD+ C R YH C L D+ ++R+ S V CR KK N +
Sbjct: 103 CFECHLPGEVLICDL--CFRVYHSKC-LSDEFRLRDSSSPWQCPV-CRSIKKKNTNKQ 156
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 35.8 bits (81), Expect = 0.062
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 9/87 (10%)
Query: 129 RKHKKTAHNSEADLE------ESFNEHELEPSSPKSKKKSRKGR--PRKTNFKGLSEDTR 180
RKHKK + +S++D + + N+ + + K KKK + + +K + K E +
Sbjct: 204 RKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSD 263
Query: 181 STSSHGTDEMESSSYRDRSPHRSSPSD 207
S+S +E + ++DR+ PSD
Sbjct: 264 SSSKESQEEFLENPWKDRT-KAEEPSD 289
Score = 32.0 bits (71), Expect = 0.90
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 145 SFNEHELEPSSPKSKKKSRKGRPRKTN---FKGLSEDTRSTSSHGTDEMESSSYR 196
S +E E + S +SK++S+K R +K++ K SED+ S S TD + + R
Sbjct: 176 STSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKR 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,266,472
Number of Sequences: 37866
Number of extensions: 727703
Number of successful extensions: 4755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 4427
Number of HSP's gapped (non-prelim): 448
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.