Search of human proteins with 28195390

Search of human proteins with 28195390

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28195390 tripartite motif-containing 42 [Homo sapiens]
         (723 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28195390 tripartite motif-containing 42 [Homo sapiens]            1535   0.0  
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]   108   1e-23
gi|223890259 midline 2 isoform 2 [Homo sapiens]                       103   4e-22
gi|223890257 midline 2 isoform 1 [Homo sapiens]                       103   4e-22
gi|148833499 midline 1 [Homo sapiens]                                 103   6e-22
gi|4557753 midline 1 [Homo sapiens]                                   103   6e-22
gi|15451852 midline 1 [Homo sapiens]                                  103   6e-22
gi|47174859 tripartite motif-containing 46 [Homo sapiens]              87   5e-17
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi...    80   7e-15
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi...    80   7e-15
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       76   1e-13
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    75   2e-13
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    75   2e-13
gi|17402909 tripartite motif protein TRIM29 [Homo sapiens]             65   2e-10
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              64   4e-10
gi|148596968 tripartite motif-containing 8 [Homo sapiens]              64   4e-10
gi|30794216 tripartite motif-containing 56 [Homo sapiens]              63   1e-09
gi|84993742 tripartite motif-containing 71 [Homo sapiens]              59   1e-08
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]      59   2e-08
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       59   2e-08
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]       59   2e-08
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    59   2e-08
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    59   2e-08
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    59   2e-08
gi|5454014 tripartite motif-containing 38 [Homo sapiens]               58   4e-08
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]       56   1e-07
gi|123702038 keratin associated protein 5-9 [Homo sapiens]             54   5e-07
gi|117938316 tripartite motif-containing 22 [Homo sapiens]             52   1e-06
gi|48255913 tripartite motif-containing 16 [Homo sapiens]              52   3e-06
gi|22749269 ring finger protein 129 [Homo sapiens]                     51   3e-06

>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
          Length = 723

 Score = 1535 bits (3975), Expect = 0.0
 Identities = 723/723 (100%), Positives = 723/723 (100%)

Query: 1   METAMCVCCPCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSES 60
           METAMCVCCPCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSES
Sbjct: 1   METAMCVCCPCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSES 60

Query: 61  PNCHWCCCSWANDPNCKCCCTASSNLNCYYYESRCCRNTIITFHKGRLRSIHTSSKTALR 120
           PNCHWCCCSWANDPNCKCCCTASSNLNCYYYESRCCRNTIITFHKGRLRSIHTSSKTALR
Sbjct: 61  PNCHWCCCSWANDPNCKCCCTASSNLNCYYYESRCCRNTIITFHKGRLRSIHTSSKTALR 120

Query: 121 TGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT 180
           TGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT
Sbjct: 121 TGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT 180

Query: 181 ENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQV 240
           ENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQV
Sbjct: 181 ENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQV 240

Query: 241 CRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIE 300
           CRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIE
Sbjct: 241 CRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIE 300

Query: 301 YCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNI 360
           YCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNI
Sbjct: 301 YCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNI 360

Query: 361 LKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKV 420
           LKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKV
Sbjct: 361 LKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKV 420

Query: 421 NEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFV 480
           NEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFV
Sbjct: 421 NEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFV 480

Query: 481 ELSSAIHELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRSSSML 540
           ELSSAIHELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRSSSML
Sbjct: 481 ELSSAIHELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRSSSML 540

Query: 541 SFSNTDKKAKVGLEACGRAQSATPAKPTDGLYTYWSAGADSQSVQNSSSFHNWYSFNDGS 600
           SFSNTDKKAKVGLEACGRAQSATPAKPTDGLYTYWSAGADSQSVQNSSSFHNWYSFNDGS
Sbjct: 541 SFSNTDKKAKVGLEACGRAQSATPAKPTDGLYTYWSAGADSQSVQNSSSFHNWYSFNDGS 600

Query: 601 VKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDIM 660
           VKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDIM
Sbjct: 601 VKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDIM 660

Query: 661 QQNLELHNLTPNTEYVFKVRAINDNGPGQWSDICKVVTPDGHGKNRAKWGLLKNIQSALQ 720
           QQNLELHNLTPNTEYVFKVRAINDNGPGQWSDICKVVTPDGHGKNRAKWGLLKNIQSALQ
Sbjct: 661 QQNLELHNLTPNTEYVFKVRAINDNGPGQWSDICKVVTPDGHGKNRAKWGLLKNIQSALQ 720

Query: 721 KHF 723
           KHF
Sbjct: 721 KHF 723


>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
          Length = 728

 Score =  108 bits (271), Expect = 1e-23
 Identities = 97/417 (23%), Positives = 169/417 (40%), Gaps = 72/417 (17%)

Query: 139 HLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQ------------------------ 174
           ++   L CP C  L  H  +LPC HS+C KC+++L                         
Sbjct: 26  NIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRL 85

Query: 175 ----------------KHAEVTENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRY 218
                           K   +T    +  CP C+    +       L  N+    + +RY
Sbjct: 86  PSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERY 145

Query: 219 MQEHGYLKWRFDRSSGPILCQVCRNR-RIAYKRCITCRLNLCNDCLKAFHS-DVAMQDHV 276
            Q          R++  I+C +C+   + + K C+ C  + CN+C K  H        H 
Sbjct: 146 RQAA--------RAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHE 197

Query: 277 FVDTSAEEQDEKI-CIHHPSSRIIEYCRNDNKLLCTFCKFSF-HNGHDTISLIDACSERA 334
           +V  +   + + + C  H + RI  YC    + +C  CK    H  H   ++  A     
Sbjct: 198 YVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLK 257

Query: 335 ASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKII 394
             L   I        ++ + + E N+L    + + E  ++E    F KL  +L+E++  +
Sbjct: 258 EKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSV 317

Query: 395 MEQIENLEVSR----QKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILV 450
           ++ I++ +  R    Q ++E+Y       + E +GL+ Y++E LKET Q  F+Q+AK L 
Sbjct: 318 LKAIDSSKKLRLDKFQTQMEEY-----QGLLENNGLVGYAQEVLKETDQSCFVQTAKQLH 372

Query: 451 DQIEDGIQT--TYRPDPQLRLHSINYVPLDFVELSSAIHELFPTGPKKVRSSGDSLP 505
            +I+   ++  ++RP  Q           D+V  +S   EL   G     SSG  +P
Sbjct: 373 LRIQKATESLKSFRPAAQTSFE-------DYVVNTSKQTELL--GELSFFSSGIDVP 420


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score =  103 bits (258), Expect = 4e-22
 Identities = 95/411 (23%), Positives = 167/411 (40%), Gaps = 37/411 (9%)

Query: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQ----KHAEVTENFFILICPVCDRSH 195
           L + L CP+C  L     +LPC HSLC  C  ++        E  E      CP C    
Sbjct: 24  LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83

Query: 196 CMPYSNKMQLPENYLHGRLTKRYMQ-----EHGYLKWRFDR--------SSGPILCQVCR 242
            + +     L  N     +  R+ +      +   + R +R        SS  I CQ C 
Sbjct: 84  SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143

Query: 243 N--RRIAYKRCITCRLNLCNDCLKAFH-SDVAMQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
               R A K CITC ++ C+ CL+A H +      H  V+   +     I C+ H + ++
Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203

Query: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
             YC +D++L+C  CK    H  H   SL D   +   +L   +        E++N + +
Sbjct: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263

Query: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
              +    + +      ++     +L  I+Q+++++I  +I+  +V + +++ + V    
Sbjct: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323

Query: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
             +     LI  ++  LKE  Q  FLQSAK + +++     ++    P +  + +     
Sbjct: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFA 383

Query: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
           LDF            +  KK+    D L +P P  +  E   A   T + H
Sbjct: 384 LDF------------SREKKLLEGLDYLTAPNPPSIREELCTASHDTITVH 422



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 621 VYWTCPAE-DVDSFEMEFYEVITSPPNNVQM----ELCGQIRDIMQQNLELHNLTPNTEY 675
           V+W    E  + S+E++ Y + T   N + +    +    + +I Q +  +H L   T Y
Sbjct: 421 VHWISDDEFSISSYELQ-YTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRY 479

Query: 676 VFKVRAINDNG 686
           +F V+AIN  G
Sbjct: 480 IFIVKAINQAG 490


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score =  103 bits (258), Expect = 4e-22
 Identities = 95/411 (23%), Positives = 167/411 (40%), Gaps = 37/411 (9%)

Query: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQ----KHAEVTENFFILICPVCDRSH 195
           L + L CP+C  L     +LPC HSLC  C  ++        E  E      CP C    
Sbjct: 24  LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83

Query: 196 CMPYSNKMQLPENYLHGRLTKRYMQ-----EHGYLKWRFDR--------SSGPILCQVCR 242
            + +     L  N     +  R+ +      +   + R +R        SS  I CQ C 
Sbjct: 84  SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143

Query: 243 N--RRIAYKRCITCRLNLCNDCLKAFH-SDVAMQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
               R A K CITC ++ C+ CL+A H +      H  V+   +     I C+ H + ++
Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203

Query: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
             YC +D++L+C  CK    H  H   SL D   +   +L   +        E++N + +
Sbjct: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263

Query: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
              +    + +      ++     +L  I+Q+++++I  +I+  +V + +++ + V    
Sbjct: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323

Query: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
             +     LI  ++  LKE  Q  FLQSAK + +++     ++    P +  + +     
Sbjct: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFA 383

Query: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
           LDF            +  KK+    D L +P P  +  E   A   T + H
Sbjct: 384 LDF------------SREKKLLEGLDYLTAPNPPSIREELCTASHDTITVH 422


>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score =  103 bits (257), Expect = 6e-22
 Identities = 93/411 (22%), Positives = 170/411 (41%), Gaps = 37/411 (9%)

Query: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCL-RQLQKHA---EVTENFFILICPVCDRSH 195
           L + L CP+C  L     +LPC HSLC  C  R L  H    E  E+     CP C    
Sbjct: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63

Query: 196 CMPYSNKMQLPENYLHGRLTKRYMQE-----HGYLKWRFDR--------SSGPILCQVCR 242
            +       L  N     +  R+ +      +   + R +R        S+  +LCQ C 
Sbjct: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123

Query: 243 N--RRIAYKRCITCRLNLCNDCLKAFHSDVA-MQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
               + A K C+TC ++ C++CLKA H +      H  ++   +     + C+ H   ++
Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183

Query: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
             YC  D++L+C  CK    H  H   +L +   +   +L S +        E++  L +
Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243

Query: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
                   + +   +  ++      L  I+Q++ +II  +I+  +V R +++ + +    
Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303

Query: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
             +     LI+ ++ +LKE     FLQ+AK + +++     ++    P++ L+ + +   
Sbjct: 304 QCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFA 363

Query: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
           LDF            +  KK+    D L +P P  +  E   A   T + H
Sbjct: 364 LDF------------SREKKLLECLDYLTAPNPPTIREELCTASYDTITVH 402



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 10/73 (13%)

Query: 621 VYWTCPAE-DVDSFEMEFYEVITSPPNNVQMELCGQ------IRDIMQQNLELHNLTPNT 673
           V+WT   E  V S+E++ Y + T   N V   LC        + +I Q +  +H L   T
Sbjct: 401 VHWTSDDEFSVVSYELQ-YTIFTGQANVVS--LCNSADSWMIVPNIKQNHYTVHGLQSGT 457

Query: 674 EYVFKVRAINDNG 686
           +Y+F V+AIN  G
Sbjct: 458 KYIFMVKAINQAG 470


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score =  103 bits (257), Expect = 6e-22
 Identities = 93/411 (22%), Positives = 170/411 (41%), Gaps = 37/411 (9%)

Query: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCL-RQLQKHA---EVTENFFILICPVCDRSH 195
           L + L CP+C  L     +LPC HSLC  C  R L  H    E  E+     CP C    
Sbjct: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63

Query: 196 CMPYSNKMQLPENYLHGRLTKRYMQE-----HGYLKWRFDR--------SSGPILCQVCR 242
            +       L  N     +  R+ +      +   + R +R        S+  +LCQ C 
Sbjct: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123

Query: 243 N--RRIAYKRCITCRLNLCNDCLKAFHSDVA-MQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
               + A K C+TC ++ C++CLKA H +      H  ++   +     + C+ H   ++
Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183

Query: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
             YC  D++L+C  CK    H  H   +L +   +   +L S +        E++  L +
Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243

Query: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
                   + +   +  ++      L  I+Q++ +II  +I+  +V R +++ + +    
Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303

Query: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
             +     LI+ ++ +LKE     FLQ+AK + +++     ++    P++ L+ + +   
Sbjct: 304 QCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFA 363

Query: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
           LDF            +  KK+    D L +P P  +  E   A   T + H
Sbjct: 364 LDF------------SREKKLLECLDYLTAPNPPTIREELCTASYDTITVH 402



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 10/73 (13%)

Query: 621 VYWTCPAE-DVDSFEMEFYEVITSPPNNVQMELCGQ------IRDIMQQNLELHNLTPNT 673
           V+WT   E  V S+E++ Y + T   N V   LC        + +I Q +  +H L   T
Sbjct: 401 VHWTSDDEFSVVSYELQ-YTIFTGQANVVS--LCNSADSWMIVPNIKQNHYTVHGLQSGT 457

Query: 674 EYVFKVRAINDNG 686
           +Y+F V+AIN  G
Sbjct: 458 KYIFMVKAINQAG 470


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score =  103 bits (257), Expect = 6e-22
 Identities = 93/411 (22%), Positives = 170/411 (41%), Gaps = 37/411 (9%)

Query: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCL-RQLQKHA---EVTENFFILICPVCDRSH 195
           L + L CP+C  L     +LPC HSLC  C  R L  H    E  E+     CP C    
Sbjct: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63

Query: 196 CMPYSNKMQLPENYLHGRLTKRYMQE-----HGYLKWRFDR--------SSGPILCQVCR 242
            +       L  N     +  R+ +      +   + R +R        S+  +LCQ C 
Sbjct: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123

Query: 243 N--RRIAYKRCITCRLNLCNDCLKAFHSDVA-MQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
               + A K C+TC ++ C++CLKA H +      H  ++   +     + C+ H   ++
Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183

Query: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
             YC  D++L+C  CK    H  H   +L +   +   +L S +        E++  L +
Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243

Query: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
                   + +   +  ++      L  I+Q++ +II  +I+  +V R +++ + +    
Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303

Query: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
             +     LI+ ++ +LKE     FLQ+AK + +++     ++    P++ L+ + +   
Sbjct: 304 QCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFA 363

Query: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
           LDF            +  KK+    D L +P P  +  E   A   T + H
Sbjct: 364 LDF------------SREKKLLECLDYLTAPNPPTIREELCTASYDTITVH 402



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 10/73 (13%)

Query: 621 VYWTCPAE-DVDSFEMEFYEVITSPPNNVQMELCGQ------IRDIMQQNLELHNLTPNT 673
           V+WT   E  V S+E++ Y + T   N V   LC        + +I Q +  +H L   T
Sbjct: 401 VHWTSDDEFSVVSYELQ-YTIFTGQANVVS--LCNSADSWMIVPNIKQNHYTVHGLQSGT 457

Query: 674 EYVFKVRAINDNG 686
           +Y+F V+AIN  G
Sbjct: 458 KYIFMVKAINQAG 470


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 67/282 (23%), Positives = 115/282 (40%), Gaps = 16/282 (5%)

Query: 188 CPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRI- 246
           CP C     +       L  N    R+ +RY Q             G ILCQ+C+   + 
Sbjct: 130 CPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSV--------GGAILCQLCKPPPLE 181

Query: 247 AYKRCITCRLNLCNDCLKAFH--SDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRN 304
           A K C  CR   CN+C K FH       Q    + T +      +C  H    +  YC+ 
Sbjct: 182 ATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDH-KEEVTHYCKT 240

Query: 305 DNKLLCTFCKFS-FHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKN 363
             +L+C  C+    H+GH    ++ A       L  ++      +  +   + E      
Sbjct: 241 CQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVR 300

Query: 364 SFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEM 423
             +   +  ++E+      L ++L+EK   +++ IE  +  R   +   +      + + 
Sbjct: 301 HTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQ-EHRSLLDG 359

Query: 424 DGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQT--TYRP 463
            GL+ Y++E LKET Q  F+Q+AK L ++I    +   T+RP
Sbjct: 360 SGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRP 401



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 11/35 (31%), Positives = 21/35 (60%)

Query: 139 HLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQL 173
           ++   L CP+C  +     +LPC H++C+ C R++
Sbjct: 26  NMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV 60


>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
           sapiens]
          Length = 562

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 69/353 (19%), Positives = 146/353 (41%), Gaps = 48/353 (13%)

Query: 145 NCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT-----------------------E 181
           +CP+C  L     +LPC H++C  CL QL+  + V                        +
Sbjct: 28  HCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQ 87

Query: 182 NFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGP-ILCQV 240
           +   ++CPVCD    +P      L  ++L        M E         R  G  ++C +
Sbjct: 88  SQIGILCPVCDAQVDLPMGGVKALTIDHL---AVNDVMLESL-------RGEGQGLVCDL 137

Query: 241 CRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKI-----CIHHPS 295
           C +R +  KRC TC+ NLC+ C +A         H  VD    +   +I     C  HP+
Sbjct: 138 CNDREVE-KRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPA 196

Query: 296 SRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDL 355
             +  +C   ++ +C  C    H  H      +   +   S++  +   +     ++  L
Sbjct: 197 EELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEAL 256

Query: 356 MEFNILKNSFKADKEAKRKEIR---NGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKY 412
            + +I+ ++ +   EA   ++R    G++K    ++E    +++Q+E++   ++  ++  
Sbjct: 257 AQIHIINSALQKRVEAVAADVRTFSEGYIK---AIEEHRDKLLKQLEDIRAQKENSLQLQ 313

Query: 413 VYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIE--DGIQTTYRP 463
                  + +M   + +++  L     +  L + +++V+++   + +Q + RP
Sbjct: 314 KAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRP 366


>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
           sapiens]
          Length = 580

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 69/353 (19%), Positives = 146/353 (41%), Gaps = 48/353 (13%)

Query: 145 NCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT-----------------------E 181
           +CP+C  L     +LPC H++C  CL QL+  + V                        +
Sbjct: 28  HCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQ 87

Query: 182 NFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGP-ILCQV 240
           +   ++CPVCD    +P      L  ++L        M E         R  G  ++C +
Sbjct: 88  SQIGILCPVCDAQVDLPMGGVKALTIDHL---AVNDVMLESL-------RGEGQGLVCDL 137

Query: 241 CRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKI-----CIHHPS 295
           C +R +  KRC TC+ NLC+ C +A         H  VD    +   +I     C  HP+
Sbjct: 138 CNDREVE-KRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPA 196

Query: 296 SRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDL 355
             +  +C   ++ +C  C    H  H      +   +   S++  +   +     ++  L
Sbjct: 197 EELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEAL 256

Query: 356 MEFNILKNSFKADKEAKRKEIR---NGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKY 412
            + +I+ ++ +   EA   ++R    G++K    ++E    +++Q+E++   ++  ++  
Sbjct: 257 AQIHIINSALQKRVEAVAADVRTFSEGYIK---AIEEHRDKLLKQLEDIRAQKENSLQLQ 313

Query: 413 VYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIE--DGIQTTYRP 463
                  + +M   + +++  L     +  L + +++V+++   + +Q + RP
Sbjct: 314 KAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRP 366


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 67/336 (19%), Positives = 134/336 (39%), Gaps = 34/336 (10%)

Query: 145 NCPMC-SRLR--LHSFMLPCNHSLCEKCLRQLQKHAEVTE-------NFFILICPVCDRS 194
           +C +C  RLR      +LPC HS C  CL      A  +        +  ++ CPVC + 
Sbjct: 64  HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVC-KQ 122

Query: 195 HCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRIAYKRCITC 254
            C        + ENY        +M++ G  K   D       C  C +   A   C+ C
Sbjct: 123 QCF----SKDIVENY--------FMRDSGS-KAATDAQDANQCCTSCEDNAPATSYCVEC 169

Query: 255 RLNLCNDCLKAFHSDVAMQDHVFVDT----SAEEQDEKICIHHPSSRIIEYCRNDNKLLC 310
              LC  C++A       +DH    T    S + +    C  H    ++ +C + + L C
Sbjct: 170 SEPLCETCVEAHQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTC 229

Query: 311 TFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKE 370
             C+ + H  H    L DA   +   L S + +       +     E   +++S +   +
Sbjct: 230 RDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKE---VRSSIRQVSD 286

Query: 371 AKRK---EIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLI 427
            +++   +++   L++   L ++ ++++   + +   +Q+ +E+  +  T      + ++
Sbjct: 287 VQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHIL 346

Query: 428 AYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRP 463
            ++  AL+     A L S K++  Q+   ++    P
Sbjct: 347 RFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP 382


>gi|74027251 tripartite motif-containing 33 protein isoform beta
           [Homo sapiens]
          Length = 1110

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 71/342 (20%), Positives = 138/342 (40%), Gaps = 37/342 (10%)

Query: 146 CPMC-----SRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT---------ENFFILICPVC 191
           C +C     SR      +LPC HS C +CL + ++   V          +   ++ CPVC
Sbjct: 125 CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVC 184

Query: 192 DRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRIAYKRC 251
            R  C     ++ L +NY        ++++        D  S  + C  C +   A   C
Sbjct: 185 -RQEC----RQIDLVDNY--------FVKDTSEAPSSSDEKSEQV-CTSCEDNASAVGFC 230

Query: 252 ITCRLNLCNDCLKAFHSDVAMQDH-------VFVDTSAEEQDEKICIHHPSSRIIEYCRN 304
           + C   LC  C++A       +DH       V     A  Q    C  H   ++  +C  
Sbjct: 231 VECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCET 290

Query: 305 DNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEF-NILKN 363
            ++L C  C+   H  H    L +A   +  ++ + +AK    +  +     +  N +K 
Sbjct: 291 CDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKE 350

Query: 364 SFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEM 423
             + +K  ++ EI+     L + + +K K +++Q+EN+   RQ ++ +     T    ++
Sbjct: 351 VNETNKRVEQ-EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQV 409

Query: 424 DGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDP 465
             ++ ++  A+      A L S +++  Q+   ++    P P
Sbjct: 410 KHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVP 451


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
           [Homo sapiens]
          Length = 1127

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 71/342 (20%), Positives = 138/342 (40%), Gaps = 37/342 (10%)

Query: 146 CPMC-----SRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT---------ENFFILICPVC 191
           C +C     SR      +LPC HS C +CL + ++   V          +   ++ CPVC
Sbjct: 125 CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVC 184

Query: 192 DRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRIAYKRC 251
            R  C     ++ L +NY        ++++        D  S  + C  C +   A   C
Sbjct: 185 -RQEC----RQIDLVDNY--------FVKDTSEAPSSSDEKSEQV-CTSCEDNASAVGFC 230

Query: 252 ITCRLNLCNDCLKAFHSDVAMQDH-------VFVDTSAEEQDEKICIHHPSSRIIEYCRN 304
           + C   LC  C++A       +DH       V     A  Q    C  H   ++  +C  
Sbjct: 231 VECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCET 290

Query: 305 DNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEF-NILKN 363
            ++L C  C+   H  H    L +A   +  ++ + +AK    +  +     +  N +K 
Sbjct: 291 CDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKE 350

Query: 364 SFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEM 423
             + +K  ++ EI+     L + + +K K +++Q+EN+   RQ ++ +     T    ++
Sbjct: 351 VNETNKRVEQ-EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQV 409

Query: 424 DGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDP 465
             ++ ++  A+      A L S +++  Q+   ++    P P
Sbjct: 410 KHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVP 451


>gi|17402909 tripartite motif protein TRIM29 [Homo sapiens]
          Length = 588

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 62/289 (21%), Positives = 121/289 (41%), Gaps = 59/289 (20%)

Query: 229 FDRS---SGPILCQVC-RNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEE 284
           F RS   S  +LC  C  N++ A K C+ C+ + C   LK      A +DH  ++   + 
Sbjct: 161 FSRSKSGSEEVLCDSCIGNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDF 220

Query: 285 QDEKICIHHPSSRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKF 344
           +  K  +H  +  +  +C+ D   +C  C F  H  H T+++ +A +E+   L       
Sbjct: 221 EARKCPVHGKTMEL--FCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETEL------- 271

Query: 345 KAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVS 404
                 +  + ++  I++   +A+K  K K+      +++S    ++ I+ +   +L   
Sbjct: 272 -----SLQKEQLQLKIIEIEDEAEKWQKEKD------RIKSFTTNEKAILEQNFRDLVRD 320

Query: 405 RQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPD 464
            +K+ E+                   + AL++  Q A +   K+++D +++  +  +  D
Sbjct: 321 LEKQKEEV------------------RAALEQREQDA-VDQVKVIMDALDERAKVLHE-D 360

Query: 465 PQLR--LHSINYVPLDFVELSSAIHELFPTGPKKVRSSGDSLPSPYPVH 511
            Q R  LHSI+   L   E  + +             S  SLP P P +
Sbjct: 361 KQTREQLHSISDSVLFLQEFGALM-------------SNYSLPPPLPTY 396


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 87/443 (19%), Positives = 165/443 (37%), Gaps = 36/443 (8%)

Query: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCMPY 199
           L   L+C +C          PC H+ C  CL +              +CP C       Y
Sbjct: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETW-----AVQGSPYLCPQCR----AVY 57

Query: 200 SNKMQLPENYLHGRLTKRYMQEHGYLKWRFD------RSSGP-----ILCQVCRNRRIAY 248
             + QL +N +   + ++++Q     +   D      R+S P     + C  C  +  A 
Sbjct: 58  QARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCL-KEAAV 116

Query: 249 KRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKL 308
           K C+ C  + C + L+      A QDH  +     +   + C  H   R   +C   ++ 
Sbjct: 117 KTCLVCMASFCQEHLQPHFDSPAFQDHP-LQPPVRDLLRRKCSQHNRLREF-FCPEHSEC 174

Query: 309 LCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKAD 368
           +C  C    H      SL  A ++  A+L   +    +        L +    +   +  
Sbjct: 175 ICHICLVE-HKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMT 233

Query: 369 KEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIA 428
              K ++++  + +++++L   E     +I+  E     + +    +   K +E+  L  
Sbjct: 234 ANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKE 293

Query: 429 YSKEALKETGQVAFLQSAKILVDQIEDGIQT--TYRPDPQLRLHSINYVPLDFVELSSAI 486
             +++L +  +  FL+ A  L      GI T   Y P+ +L    I  +    ++L + +
Sbjct: 294 EIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGIHQSTIDLKNEL 348

Query: 487 HELFPTGPKKVRSSGD-SLPSPYPVHSETMIARKVT-FSTHSLGNQHIYQRSSSMLSFSN 544
            +      +   SSGD     P   H  T   +KV+     S     +    S + +F  
Sbjct: 349 KQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGA 408

Query: 545 TDKKA---KVGLEACGRAQSATP 564
            ++     + GLEA  +A S+ P
Sbjct: 409 PEQLVDLKQAGLEAAAKATSSHP 431


>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
          Length = 551

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 62/328 (18%), Positives = 131/328 (39%), Gaps = 26/328 (7%)

Query: 144 LNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCMPYSNKM 203
           L CP+C  + +    LPC H+ C  C+ +        ++  ++ CP C+++    Y+ K 
Sbjct: 13  LICPICLHVFVEPVQLPCKHNFCRGCIGEAW-----AKDSGLVRCPECNQA----YNQKP 63

Query: 204 QLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRN--RRIAYKRCITCRLNLCND 261
            L +N     + +++   H       ++    + C  CR      A K C+ C    C  
Sbjct: 64  GLEKNLKLTNIVEKFNALH------VEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQS 117

Query: 262 CLKA-FHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCKF--SFH 318
            ++         + H+ V+  A++     C  H + R+  +C  +   +C +C +    H
Sbjct: 118 HVQTHLQQPSTARGHLLVE--ADDVRAWSCPQHNAYRLY-HCEAEQVAVCQYCCYYSGAH 174

Query: 319 NGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRN 378
            GH    +    +E    L     + +    +I++ L +    K   +      ++E+R 
Sbjct: 175 QGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRL 234

Query: 379 GFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETG 438
            + KL  +L E  +  +E ++  +     E          ++ E   L+   +    +T 
Sbjct: 235 QYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTE 294

Query: 439 QVAFL---QSAKILVDQIEDGIQTTYRP 463
            V+F+   +S KIL+D+ +    ++  P
Sbjct: 295 DVSFMKNTKSVKILMDRTQTCTSSSLSP 322


>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
          Length = 755

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 68/296 (22%), Positives = 113/296 (38%), Gaps = 51/296 (17%)

Query: 144 LNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCMPYSNKM 203
           L C +C         LPC H+ C+ CL QL     V        CP C  +  +P     
Sbjct: 19  LACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVR-------CPECRETVPVPPEGVA 71

Query: 204 QLPENY-LHGRLTKRYMQEHGYLKWRFDRSSGPILCQVC------RNRRIAYKRCITCRL 256
               N+ ++G L     +  G L+      +G   C +C           A  RC+ C  
Sbjct: 72  SFKTNFFVNGLLDLVKARACGDLR------AGKPACALCPLVGGTSTGGPATARCLDCAD 125

Query: 257 NLCNDCLKAFHSDVAMQDHVFVDT----------SAEEQDEKICIHHPSSRIIEYCRNDN 306
           +LC  C            H  VD            A E+    C  HP   +   C+  +
Sbjct: 126 DLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCS 185

Query: 307 KLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFK 366
           +LLC  C+   H  H  + L +A   R   L   +A        +DN+L+E   L+ + +
Sbjct: 186 QLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLA-------GVDNNLVE---LEAARR 235

Query: 367 ADKEA----KRKEIRNGFL-------KLRSILQEKEKIIMEQIENLEVSRQKEIEK 411
            +KEA    + +  R G          LR++L +K++++ +   ++E + +   E+
Sbjct: 236 VEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARER 291


>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
          Length = 868

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 44/245 (17%), Positives = 94/245 (38%), Gaps = 27/245 (11%)

Query: 238 CQVCRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHV--------------------- 276
           C  C     A  RC+ C+ +LC++C++A       +DH                      
Sbjct: 199 CSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPGAAAAAQQLGLGP 258

Query: 277 ------FVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDAC 330
                 F   S   +    C HH    +  YC   +  +C  C    H GH  I L +A 
Sbjct: 259 PFPGPPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTMGRHGGHSFIYLQEAL 318

Query: 331 SERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEK 390
            +  A     +A  +  R  I   + +   +    +   +  + E++    + +  L+E+
Sbjct: 319 QDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEER 378

Query: 391 EKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILV 450
           E  ++ ++E +   + K +   V      +N+++  I+  ++ L+E   +  L +   ++
Sbjct: 379 ECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRML 438

Query: 451 DQIED 455
            Q+++
Sbjct: 439 AQVQE 443


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 34/128 (26%), Positives = 69/128 (53%), Gaps = 11/128 (8%)

Query: 289 ICIHHPSSRIIEYCRNDNKLLCTFCKFSF-HNGHDTI---SLIDACSERAASLFSAIAKF 344
           +C HH   +++ +C+ D K++C  C+ S  H GH T+    +   C E+  ++   + K 
Sbjct: 96  LCDHH-GEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKE 154

Query: 345 KAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVS 404
           +    +++ D+ E    K S+K   + +R+ I+  F +LRSIL  +E+    +++ LE  
Sbjct: 155 EEEAEKLEADIREE---KTSWKYQVQTERQRIQTEFDQLRSILNNEEQ---RELQRLEEE 208

Query: 405 RQKEIEKY 412
            +K ++K+
Sbjct: 209 EKKTLDKF 216


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 34/128 (26%), Positives = 69/128 (53%), Gaps = 11/128 (8%)

Query: 289 ICIHHPSSRIIEYCRNDNKLLCTFCKFSF-HNGHDTI---SLIDACSERAASLFSAIAKF 344
           +C HH   +++ +C+ D K++C  C+ S  H GH T+    +   C E+  ++   + K 
Sbjct: 96  LCDHH-GEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKE 154

Query: 345 KAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVS 404
           +    +++ D+ E    K S+K   + +R+ I+  F +LRSIL  +E+    +++ LE  
Sbjct: 155 EEEAEKLEADIREE---KTSWKYQVQTERQRIQTEFDQLRSILNNEEQ---RELQRLEEE 208

Query: 405 RQKEIEKY 412
            +K ++K+
Sbjct: 209 EKKTLDKF 216


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 34/128 (26%), Positives = 69/128 (53%), Gaps = 11/128 (8%)

Query: 289 ICIHHPSSRIIEYCRNDNKLLCTFCKFSF-HNGHDTI---SLIDACSERAASLFSAIAKF 344
           +C HH   +++ +C+ D K++C  C+ S  H GH T+    +   C E+  ++   + K 
Sbjct: 96  LCDHH-GEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKE 154

Query: 345 KAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVS 404
           +    +++ D+ E    K S+K   + +R+ I+  F +LRSIL  +E+    +++ LE  
Sbjct: 155 EEEAEKLEADIREE---KTSWKYQVQTERQRIQTEFDQLRSILNNEEQ---RELQRLEEE 208

Query: 405 RQKEIEKY 412
            +K ++K+
Sbjct: 209 EKKTLDKF 216


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 34/128 (26%), Positives = 69/128 (53%), Gaps = 11/128 (8%)

Query: 289 ICIHHPSSRIIEYCRNDNKLLCTFCKFS-FHNGHDTI---SLIDACSERAASLFSAIAKF 344
           +C HH   +++ +C+ D K++C  C+ S  H GH T+    +   C E+  ++   + K 
Sbjct: 450 LCDHH-GEKLLLFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKE 508

Query: 345 KAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVS 404
           +    +++ D+ E    K S+K   + +R+ I+  F +LRSIL  +E+    +++ LE  
Sbjct: 509 EEEAEKLEADIRE---EKTSWKYQVQTERQRIQTEFDQLRSILNNEEQ---RELQRLEEE 562

Query: 405 RQKEIEKY 412
            +K ++K+
Sbjct: 563 EKKTLDKF 570



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 2/124 (1%)

Query: 289 ICIHHPSSRIIEYCRNDNKLLCTFCKFSF-HNGHDTISLIDACSERAASLFSAIAKFKAV 347
           +C  H   ++  +C+ D K++C  C+ S  H GH T  + +   E       ++ K K  
Sbjct: 124 LCADH-GEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNE 182

Query: 348 RYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQK 407
             E +         K S+K   E +R  I+  F +LR+IL   E+  ++++E  E    +
Sbjct: 183 EQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLR 242

Query: 408 EIEK 411
            IE+
Sbjct: 243 IIEE 246



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 30/150 (20%), Positives = 54/150 (36%), Gaps = 19/150 (12%)

Query: 106 GRLRSIHTSSKTALRTGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSL 165
           G  R +   +   +R G +  +     + P    +   + CP+C  L      + C HS 
Sbjct: 3   GSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSF 62

Query: 166 CEKCLRQLQKHAEVTENFFILICPVCDRSHCMPYSNKMQLPENYL-------------HG 212
           C+ C+    + + + +      CPVC  S    Y      P  +L              G
Sbjct: 63  CQACITPNGRESVIGQE-GERSCPVCQTS----YQPGNLRPNRHLANIVRRLREVVLGPG 117

Query: 213 RLTKRYM-QEHGYLKWRFDRSSGPILCQVC 241
           +  K  +  +HG     F +  G ++C +C
Sbjct: 118 KQLKAVLCADHGEKLQLFCQEDGKVICWLC 147


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 79/429 (18%), Positives = 170/429 (39%), Gaps = 45/429 (10%)

Query: 158 MLPCNHSLCEKCLRQLQKHAEV-------TENFFILICPVCDRSHCMPYSNKMQLPENYL 210
           +LPC HS C++CL   Q++  +        E    +  P    S   P++ ++ +    +
Sbjct: 70  LLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPV 129

Query: 211 HGR-LTKRYMQEHGYLKWRFDRSSGPI-----LCQVCRNRRIAYKRCITCRLNLCNDCLK 264
             +   +R++ ++ ++K   +  S  +     +C  C +   A   C+ C   LC  C++
Sbjct: 130 CSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIR 189

Query: 265 AFHSDVAMQDHVF---VDTSAE-----EQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFS 316
           A       +DH      + S E      Q    C  H   ++  YC   +KL C  C+  
Sbjct: 190 AHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDKLTCRDCQLL 249

Query: 317 FHNGHDTISLIDACSERAASLFSAIAKF----KAVRY---EIDNDLMEFNILKNSFKADK 369
            H  H    + +A   +   + + I K     K +++   +I N ++E N        ++
Sbjct: 250 EHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVN-------QNQ 302

Query: 370 EAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAY 429
           +   ++I+     L   + +K K ++ Q+E+L    + ++ +          +++ ++ +
Sbjct: 303 KQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHF 362

Query: 430 SKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDP----QLRLH-SINYVPLDFVELSS 484
           SK A+      A L S +++  ++   ++      P     ++ H   ++   + + L S
Sbjct: 363 SKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINLGS 422

Query: 485 AI---HELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRS--SSM 539
            +    E  P  PK+      +   P  + S  +       S   L  QH+ Q+     +
Sbjct: 423 LVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPPRL 482

Query: 540 LSFSNTDKK 548
           ++F N   K
Sbjct: 483 INFQNHSPK 491


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 61/320 (19%), Positives = 132/320 (41%), Gaps = 35/320 (10%)

Query: 158 MLPCNHSLCEKCLRQLQKHAEV-------TENFFILICPVCDRSHCMPYSNKMQLPENYL 210
           +LPC HS C++CL   Q++  +        E    +  P    S   P++ ++ +    +
Sbjct: 70  LLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPV 129

Query: 211 HGR-LTKRYMQEHGYLKWRFDRSSGPI-----LCQVCRNRRIAYKRCITCRLNLCNDCLK 264
             +   +R++ ++ ++K   +  S  +     +C  C +   A   C+ C   LC  C++
Sbjct: 130 CSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIR 189

Query: 265 AFHSDVAMQDHVF---VDTSAE-----EQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFS 316
           A       +DH      + S E      Q    C  H   ++  YC   +KL C  C+  
Sbjct: 190 AHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDKLTCRDCQLL 249

Query: 317 FHNGHDTISLIDACSERAASLFSAIAKF----KAVRY---EIDNDLMEFNILKNSFKADK 369
            H  H    + +A   +   + + I K     K +++   +I N ++E N        ++
Sbjct: 250 EHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVN-------QNQ 302

Query: 370 EAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAY 429
           +   ++I+     L   + +K K ++ Q+E+L    + ++ +          +++ ++ +
Sbjct: 303 KQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHF 362

Query: 430 SKEALKETGQVAFLQSAKIL 449
           SK A+      A L S +++
Sbjct: 363 SKWAVSSGSSTALLYSKRLI 382


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 42/185 (22%), Positives = 75/185 (40%), Gaps = 5/185 (2%)

Query: 259 CNDCLKAFHSDVAMQDHVF---VDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCKF 315
           C  C   FH D    +      ++   E   E  C  H   +   +C ++ +L+C  C+ 
Sbjct: 59  CPQCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEH-GEQFHLFCEDEGQLICWRCER 117

Query: 316 S-FHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRK 374
           +  H GH T  + D C      L  A+ K K +        +   +    +K   + +R+
Sbjct: 118 APQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQ 177

Query: 375 EIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEAL 434
           +IR+ F  L+  L E+EK  + ++E  E      +  Y     +K NE+   I   +E  
Sbjct: 178 KIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKC 237

Query: 435 KETGQ 439
           + + Q
Sbjct: 238 QGSAQ 242



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 26/115 (22%), Positives = 42/115 (36%), Gaps = 8/115 (6%)

Query: 133 SIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKH---AEVTENFFILICP 189
           S  +   ++    C +C  L  +   + C HS C  C+    K+    ++ +  F   CP
Sbjct: 3   STTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETF--CCP 60

Query: 190 VCDRS-HCMPYSNKMQLPENYLHGRLTKRYM--QEHGYLKWRFDRSSGPILCQVC 241
            C    H        QL       + T + M  +EHG     F    G ++C  C
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRC 115


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 65/353 (18%), Positives = 125/353 (35%), Gaps = 48/353 (13%)

Query: 139 HLVNHLNCPMCSRLRLHSFM-LPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCM 197
           +L   L CP+C  +     + LPC H+LC KC   +                        
Sbjct: 16  NLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDI------------------------ 51

Query: 198 PYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRIAYKRCITCRLN 257
                 Q    Y   R +   M            S G   C  CR+  I  +  +     
Sbjct: 52  -----FQAANPYWTSRGSSVSM------------SGGRFRCPTCRHEVIMDRHGV---YG 91

Query: 258 LCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCK-FS 316
           L  + L     D+  Q+        ++    +C  H   +I  YC       C+ CK F 
Sbjct: 92  LQRNLLVENIIDIYKQE--CSSRPLQKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFG 149

Query: 317 FHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEI 376
            H   +   L      +   L + I+   A    +   + +    +   K +    ++E+
Sbjct: 150 IHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEEL 209

Query: 377 RNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKE 436
              F  L +IL EK+  ++++I   +  +   IE  +     ++++   L+  + ++L E
Sbjct: 210 SQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDE 269

Query: 437 TGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFVELSSAIHEL 489
            G   FL +AK L+  I +  +       +    ++++  LD   ++ A+  +
Sbjct: 270 PGGATFLLTAKQLIKSIVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAI 322


>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
          Length = 169

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 32/94 (34%), Positives = 38/94 (40%), Gaps = 12/94 (12%)

Query: 4   AMCVCC-PCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSESPN 62
           + C CC PCC    C    C C CCK  + S+ +C C PC     R    C  +C     
Sbjct: 78  SQCSCCKPCCCSSGCGSSCCQCSCCK-PYCSQCSC-CKPCCSSSGRGSSCCQSSC----- 130

Query: 63  CHWCCCSWANDPNCKCCCTASSNLNCYYYESRCC 96
           C  CC S      C   C  SS       +SRCC
Sbjct: 131 CKPCCSS----SGCGSSCCQSSCCKPCCSQSRCC 160



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 17/102 (16%)

Query: 8   CCP--CCTWQRCCPQLCSCLCCKFIFTSERNC--------TCFPCPYKDERNCQFCHCTC 57
           C P  CC    CC   CSC  C      +R C         C  C       C+ C C+ 
Sbjct: 36  CAPVYCCKPVCCCVPACSCSSC-----GKRGCGSCGGSKGGCGSCGCSQCSCCKPCCCSS 90

Query: 58  SESPNCHWCCCSWANDPNCKCC--CTASSNLNCYYYESRCCR 97
               +C  C C       C CC  C +SS       +S CC+
Sbjct: 91  GCGSSCCQCSCCKPYCSQCSCCKPCCSSSGRGSSCCQSSCCK 132


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 40/185 (21%), Positives = 82/185 (44%), Gaps = 18/185 (9%)

Query: 234 GPILCQVCRNRRIAYKRCITCRLNLCNDCLKAFH----------SDVAMQDHVFVDTSAE 283
           G   CQ C   +I     I+   + C  C   F           +++  +      +  E
Sbjct: 31  GHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRPNRHLANIVERVKEVKMSPQE 90

Query: 284 EQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFS-FHNGHDTI---SLIDACSERAASLFS 339
            Q   +C HH   ++  +C+ D K++C  C+ S  H GH T     ++  C E+      
Sbjct: 91  GQKRDVCEHH-GKKLQIFCKEDGKVICWVCELSQEHQGHQTFRINEVVKECQEKLQVALQ 149

Query: 340 AIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIE 399
            + K      ++++D+ +    + ++K   + +R++I  GF ++R IL  +E+  ++++E
Sbjct: 150 RLIKEDQEAEKLEDDIRQ---ERTAWKNYIQIERQKILKGFNEMRVILDNEEQRELQKLE 206

Query: 400 NLEVS 404
             EV+
Sbjct: 207 EGEVN 211



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/161 (23%), Positives = 68/161 (42%), Gaps = 23/161 (14%)

Query: 144 LNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFI----LICPVCDR----SH 195
           + CP+C  L      L C HS C+ C+      A++ E+  I      CPVC       +
Sbjct: 13  VTCPICLELLTEPLSLDCGHSFCQACIT-----AKIKESVIISRGESSCPVCQTRFQPGN 67

Query: 196 CMPYSNKMQLPENYLHGRLTKRYMQE------HGYLKWRFDRSSGPILCQVCRNRRIAYK 249
             P  +   + E     +++ +  Q+      HG     F +  G ++C VC   +  ++
Sbjct: 68  LRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQ-EHQ 126

Query: 250 RCITCRLN-LCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKI 289
              T R+N +  +C +     VA+Q  +  D  AE+ ++ I
Sbjct: 127 GHQTFRINEVVKECQEKL--QVALQRLIKEDQEAEKLEDDI 165


>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
          Length = 564

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 49/197 (24%), Positives = 85/197 (43%), Gaps = 28/197 (14%)

Query: 236 ILCQVCRN--RRI-AYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIH 292
           +LC  C +  RR+ A K C+TC +N C + L+    ++ +Q H+  +   +        H
Sbjct: 75  VLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAH 134

Query: 293 HPSSRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASL--------------F 338
           H  S +  +C  D + +C  C    H+GH  +SL  A  ++ A L               
Sbjct: 135 H--SPLSAFCCPDQQCICQDC-CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNE 191

Query: 339 SAIAKFKAVRYEIDNDLMEFN-ILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQ 397
           +AI++ +A +  +   + E   + +  F     A RK   N  L     L+EKE+  + Q
Sbjct: 192 NAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVML----FLEEKEQAALSQ 247

Query: 398 IENLEVS---RQKEIEK 411
              ++     R  E+EK
Sbjct: 248 ANGIKAHLEYRSAEMEK 264


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 63/300 (21%), Positives = 109/300 (36%), Gaps = 72/300 (24%)

Query: 134 IPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDR 193
           + A  +L    +CP+C         + C H+ C  CL    K  + T       CPVC  
Sbjct: 4   VTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDT-----FPCPVC-- 56

Query: 194 SHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRIAYKRCIT 253
             C PY +  + P+      + K+                     Q+ R++R   K    
Sbjct: 57  RFCFPYKSFRRNPQLRNLTEIAKQ--------------------LQIRRSKRKRQKENAM 96

Query: 254 CRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFC 313
           C  +  N  L  F                                   C  D ++LCT C
Sbjct: 97  CEKH--NQFLTLF-----------------------------------CVKDLEILCTQC 119

Query: 314 KFSF-HNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAK 372
            FS  H  H    +  A S     L  ++   +     ++  ++         K   E K
Sbjct: 120 SFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYK 179

Query: 373 RKEIRNGFLKLRSILQEKEKIIMEQIENLEVS-----RQKEIEKYVYVTTMK--VNEMDG 425
           R+EI + F ++R  LQ ++++I+ QI++ E++      +  +E   YV+T+K  + E++G
Sbjct: 180 REEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEG 239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,056,830
Number of Sequences: 37866
Number of extensions: 1364256
Number of successful extensions: 8640
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 275
Number of HSP's that attempted gapping in prelim test: 6491
Number of HSP's gapped (non-prelim): 1565
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.