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Search of human proteins with 27883876
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27883876 T cell immunoreceptor with Ig and ITIM domains
[Homo sapiens]
(244 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27883876 T cell immunoreceptor with Ig and ITIM domains [Homo... 499 e-142
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 52 5e-07
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 41 0.001
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 41 0.001
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 40 0.001
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 40 0.001
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 40 0.001
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 40 0.002
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 40 0.002
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 40 0.002
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 40 0.002
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 40 0.002
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 38 0.007
gi|38683840 CD96 antigen isoform 1 precursor [Homo sapiens] 36 0.035
gi|5032141 CD96 antigen isoform 2 precursor [Homo sapiens] 36 0.035
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 36 0.035
gi|8393638 F11 receptor precursor [Homo sapiens] 35 0.060
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 35 0.078
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 35 0.078
gi|4759066 sodium channel, voltage-gated, type II, beta [Homo sa... 33 0.30
gi|118572606 hemicentin 1 [Homo sapiens] 33 0.30
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 33 0.30
gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo... 33 0.30
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 32 0.39
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 32 0.39
gi|110349719 titin isoform N2-A [Homo sapiens] 32 0.50
gi|5174411 CD5 molecule-like [Homo sapiens] 32 0.50
gi|211904177 hypothetical protein LOC388336 [Homo sapiens] 32 0.50
gi|90903245 CD200 antigen isoform b [Homo sapiens] 32 0.66
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens] 32 0.66
>gi|27883876 T cell immunoreceptor with Ig and ITIM domains [Homo
sapiens]
Length = 244
Score = 499 bits (1285), Expect = e-142
Identities = 244/244 (100%), Positives = 244/244 (100%)
Query: 1 MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWE 60
MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWE
Sbjct: 1 MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWE 60
Query: 61 QQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYTG 120
QQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYTG
Sbjct: 61 QQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYTG 120
Query: 121 RIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLR 180
RIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLR
Sbjct: 121 RIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLR 180
Query: 181 RKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFF 240
RKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFF
Sbjct: 181 RKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFF 240
Query: 241 TETG 244
TETG
Sbjct: 241 TETG 244
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 52.0 bits (123), Expect = 5e-07
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 17/137 (12%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQC-HLSSTTAQVTQVNWEQ 61
W LLL L A G +ET+ ++ G L C + + QV QV W +
Sbjct: 15 WLLLL-----LLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWAR 69
Query: 62 QD-----QLLAICNADLGWHISPSFKDRVAPGPGL------GLTLQSLTVNDTGEYFCIY 110
D Q LA+ ++ G H+SP+++ RV P + L++ D GEY C
Sbjct: 70 VDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRV 129
Query: 111 HTYPDGAYTGRIFLEVL 127
T+P G++ R+ L VL
Sbjct: 130 STFPAGSFQARLRLRVL 146
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 40.8 bits (94), Expect = 0.001
Identities = 39/155 (25%), Positives = 60/155 (38%), Gaps = 44/155 (28%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTA--QVTQVNWE 60
W LLL+ L +G ++ + + GG++ L CHL ++ V W+
Sbjct: 19 WPLLLLLL-------LETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQ 71
Query: 61 QQD-----QLLAICNADLGWHISPSFKDRVAPGPG-----------------------LG 92
+ D Q +A + +G PSF +P PG
Sbjct: 72 RPDAPANHQNVAAFHPKMG----PSFP---SPKPGSERLSFVSAKQSTGQDTEAELQDAT 124
Query: 93 LTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVL 127
L L LTV D G Y C + T+P G+ G +L V+
Sbjct: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVI 159
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 40.8 bits (94), Expect = 0.001
Identities = 39/155 (25%), Positives = 60/155 (38%), Gaps = 44/155 (28%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTA--QVTQVNWE 60
W LLL+ L +G ++ + + GG++ L CHL ++ V W+
Sbjct: 19 WPLLLLLL-------LETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQ 71
Query: 61 QQD-----QLLAICNADLGWHISPSFKDRVAPGPG-----------------------LG 92
+ D Q +A + +G PSF +P PG
Sbjct: 72 RPDAPANHQNVAAFHPKMG----PSFP---SPKPGSERLSFVSAKQSTGQDTEAELQDAT 124
Query: 93 LTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVL 127
L L LTV D G Y C + T+P G+ G +L V+
Sbjct: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVI 159
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 21 GMMTGTIETTGNISAEKGGSIILQCHLSST--TAQVTQVNWEQQD----QLLAICNADLG 74
G+ + ++ ++ G ++L C ++ + ++TQV W++ Q +AI N +G
Sbjct: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMG 86
Query: 75 WHISPSFKDRVA---PGPGLG-LTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVL 127
+ +++RV P G + L L + D G Y C + T+P G ++ L V+
Sbjct: 87 VSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVM 143
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 21 GMMTGTIETTGNISAEKGGSIILQCHLSST--TAQVTQVNWEQQD----QLLAICNADLG 74
G+ + ++ ++ G ++L C ++ + ++TQV W++ Q +AI N +G
Sbjct: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMG 86
Query: 75 WHISPSFKDRVA---PGPGLG-LTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVL 127
+ +++RV P G + L L + D G Y C + T+P G ++ L V+
Sbjct: 87 VSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVM 143
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 21 GMMTGTIETTGNISAEKGGSIILQCHLSST--TAQVTQVNWEQQD----QLLAICNADLG 74
G+ + ++ ++ G ++L C ++ + ++TQV W++ Q +AI N +G
Sbjct: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMG 86
Query: 75 WHISPSFKDRVA---PGPGLG-LTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVL 127
+ +++RV P G + L L + D G Y C + T+P G ++ L V+
Sbjct: 87 VSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVM 143
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/104 (25%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 21 GMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQ----QDQLLAICNADLGWH 76
G + G I +++A G ++ L+C L +TQ++WE+ Q +A+ + G+
Sbjct: 54 GALAGPIIVEPHVTAVWGKNVSLKC-LIEVNETITQISWEKIHGKSSQTVAVHHPQYGFS 112
Query: 77 ISPSFKDRVA----PGPGLGLTLQSLTVNDTGEYFCIYHTYPDG 116
+ ++ RV +TL ++ +D+G+Y C T+P G
Sbjct: 113 VQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLG 156
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVT---QVNW 59
W LLL+ L P +G + ++ + G S+ L C+L +VT Q+ W
Sbjct: 9 WPLLLVALLVLSWPPPGTGDVV--VQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTW 66
Query: 60 EQQDQL--LAICNADLGWHISPSFK-DRVAPGPGL-----GLTLQSLTVNDTGEYFCIYH 111
+ + +A+ + G S S + + VA G L + L V D G Y C++
Sbjct: 67 ARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFV 126
Query: 112 TYPDGAYTGRIFLEVL 127
T+P G+ + I+L VL
Sbjct: 127 TFPQGSRSVDIWLRVL 142
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVT---QVNW 59
W LLL+ L P +G + ++ + G S+ L C+L +VT Q+ W
Sbjct: 9 WPLLLVALLVLSWPPPGTGDVV--VQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTW 66
Query: 60 EQQDQL--LAICNADLGWHISPSFK-DRVAPGPGL-----GLTLQSLTVNDTGEYFCIYH 111
+ + +A+ + G S S + + VA G L + L V D G Y C++
Sbjct: 67 ARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFV 126
Query: 112 TYPDGAYTGRIFLEVL 127
T+P G+ + I+L VL
Sbjct: 127 TFPQGSRSVDIWLRVL 142
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVT---QVNW 59
W LLL+ L P +G + ++ + G S+ L C+L +VT Q+ W
Sbjct: 9 WPLLLVALLVLSWPPPGTGDVV--VQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTW 66
Query: 60 EQQDQL--LAICNADLGWHISPSFK-DRVAPGPGL-----GLTLQSLTVNDTGEYFCIYH 111
+ + +A+ + G S S + + VA G L + L V D G Y C++
Sbjct: 67 ARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFV 126
Query: 112 TYPDGAYTGRIFLEVL 127
T+P G+ + I+L VL
Sbjct: 127 TFPQGSRSVDIWLRVL 142
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 3 WCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVT---QVNW 59
W LLL+ L P +G + ++ + G S+ L C+L +VT Q+ W
Sbjct: 9 WPLLLVALLVLSWPPPGTGDVV--VQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTW 66
Query: 60 EQQDQL--LAICNADLGWHISPSFK-DRVAPGPGL-----GLTLQSLTVNDTGEYFCIYH 111
+ + +A+ + G S S + + VA G L + L V D G Y C++
Sbjct: 67 ARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFV 126
Query: 112 TYPDGAYTGRIFLEVL 127
T+P G+ + I+L VL
Sbjct: 127 TFPQGSRSVDIWLRVL 142
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 38.1 bits (87), Expect = 0.007
Identities = 36/166 (21%), Positives = 71/166 (42%), Gaps = 20/166 (12%)
Query: 6 LLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTA--------QVTQV 57
LL+W + +A+ + E+ G+I +G +L C +++ A VT +
Sbjct: 6 LLLWWNCFSRTGVAASLEVS--ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPL 63
Query: 58 NWEQQDQLLAICNADLGWHISPSFKDRVA-----PGPGLGLTLQSLTVNDTGEYFCIYHT 112
+ Q + + + + +P F RV P + + + + ++DTG Y C+ +
Sbjct: 64 SNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNN 123
Query: 113 YPD--GAYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTA 156
PD G G L VL A H QI + + ++++C++
Sbjct: 124 LPDIGGRNIGVTGLTVLVPPSAPH---CQIQGSQDIGSDVILLCSS 166
>gi|38683840 CD96 antigen isoform 1 precursor [Homo sapiens]
Length = 585
Score = 35.8 bits (81), Expect = 0.035
Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 12/116 (10%)
Query: 15 QAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQ---QDQLLAICNA 71
Q G+ T+ T N+ A G + L C + T Q+ W + + L+A+ +
Sbjct: 15 QIHFVKGVWEKTVNTEENVYATLGSDVNLTCQ-TQTVGFFVQMQWSKVTNKIDLIAVYHP 73
Query: 72 DLGWHIS--------PSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYT 119
G++ + +F + G L L++++ + +G Y C+ YP+G T
Sbjct: 74 QYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQT 129
>gi|5032141 CD96 antigen isoform 2 precursor [Homo sapiens]
Length = 569
Score = 35.8 bits (81), Expect = 0.035
Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 12/116 (10%)
Query: 15 QAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQ---QDQLLAICNA 71
Q G+ T+ T N+ A G + L C + T Q+ W + + L+A+ +
Sbjct: 15 QIHFVKGVWEKTVNTEENVYATLGSDVNLTCQ-TQTVGFFVQMQWSKVTNKIDLIAVYHP 73
Query: 72 DLGWHIS--------PSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYT 119
G++ + +F + G L L++++ + +G Y C+ YP+G T
Sbjct: 74 QYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQT 129
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 35.8 bits (81), Expect = 0.035
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 18/144 (12%)
Query: 28 ETTGNISAEKGGSIILQCHLSSTTA--------QVTQVNWEQQDQLLAICNADLGWHISP 79
E+ G+I +G +L C +++ A VT ++ Q + + + + +P
Sbjct: 27 ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDGAP 86
Query: 80 SFKDRVA-----PGPGLGLTLQSLTVNDTGEYFCIYHTYPD--GAYTGRIFLEVLESSVA 132
F RV P + + + + ++DTG Y C+ + PD G G L VL A
Sbjct: 87 RFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA 146
Query: 133 EHGARFQIPLLGAMAATLVVICTA 156
H QI + + ++++C++
Sbjct: 147 PH---CQIQGSQDIGSDVILLCSS 167
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 35.0 bits (79), Expect = 0.060
Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 5 LLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQ 64
LL ++ + LA G +T + + + + L C S ++ + ++Q D
Sbjct: 11 LLCLFILAILLCSLALGSVT-VHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDT 69
Query: 65 LLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCI 109
+C + I+ S++DRV P G+T +S+T DTG Y C+
Sbjct: 70 TRLVCYNN---KITASYEDRVTFLP-TGITFKSVTREDTGTYTCM 110
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 34.7 bits (78), Expect = 0.078
Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 28/171 (16%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVA 86
IE N A +G + +LQC LS + V W + + L DR +
Sbjct: 3805 IEDVKNQEAREGATAVLQCELS----KAAPVEWRKGSETLR-------------GGDRYS 3847
Query: 87 ---PGPGLGLTLQSLTVNDTGEYFCIY-HTYPDGAYTGR----IFLEVLESSVAEHGARF 138
G L + L+V DTGEY C+ T R +F E L+S AE G+
Sbjct: 3848 LRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTA 3907
Query: 139 QIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVE---GDLRRKSAGQ 186
+ + VV + + A R++ L+ + E DL+R+ G+
Sbjct: 3908 TLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGE 3958
Score = 33.5 bits (75), Expect = 0.17
Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 13/76 (17%)
Query: 33 ISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLG 92
+ E GG++ L C LS A+V W + L + F+ VA GP
Sbjct: 1818 VCGELGGTVTLACELSPACAEVV---WRCGNTQL---------RVGKRFQ-MVAEGPVRS 1864
Query: 93 LTLQSLTVNDTGEYFC 108
LT+ L D GEY C
Sbjct: 1865 LTVLGLRAEDAGEYVC 1880
Score = 32.3 bits (72), Expect = 0.39
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 29/89 (32%)
Query: 28 ETTGNISAEKGGSIILQCHLSSTTAQVT--------QVNWEQQDQLLAICNADLGWHISP 79
E ++ AE+G + LQC LS TA V Q N ++ +L C A+
Sbjct: 3894 EPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQG-CTAE------- 3945
Query: 80 SFKDRVAPGPGLGLTLQSLTVNDTGEYFC 108
L LQ L DTGEY C
Sbjct: 3946 -------------LVLQDLQREDTGEYTC 3961
Score = 30.4 bits (67), Expect = 1.5
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 20/86 (23%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVA 86
IE N A +G + +LQC L+S V W + + L DR +
Sbjct: 3541 IEDVKNQEAREGATAVLQCELNS----AAPVEWRKGSETL-------------RDGDRYS 3583
Query: 87 ---PGPGLGLTLQSLTVNDTGEYFCI 109
G L ++ L + DTGEY C+
Sbjct: 3584 LRQDGTKCELQIRGLAMADTGEYSCV 3609
Score = 29.3 bits (64), Expect = 3.3
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFK-DRV 85
++ ++SAE+ G++ LQC +S A V W + G + PS K D +
Sbjct: 2650 LKALDDLSAEERGTLALQCEVSDPEAHVV---WRKD-----------GVQLGPSDKYDFL 2695
Query: 86 APGPGLGLTLQSLTVNDTGEYFC 108
GL + ++ D G Y C
Sbjct: 2696 HTAGTRGLVVHDVSPEDAGLYTC 2718
Score = 28.5 bits (62), Expect = 5.6
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 12/100 (12%)
Query: 28 ETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAP 87
E + +AE G ++ L C ++ T V ++W + + + + P P
Sbjct: 6018 EELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAV---------QVDPHHILIEDP 6066
Query: 88 GPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYT-GRIFLEV 126
L L SLT D+G+Y C + T G+I ++V
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 34.7 bits (78), Expect = 0.078
Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 28/171 (16%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVA 86
IE N A +G + +LQC LS + V W + + L DR +
Sbjct: 3805 IEDVKNQEAREGATAVLQCELS----KAAPVEWRKGSETLR-------------GGDRYS 3847
Query: 87 ---PGPGLGLTLQSLTVNDTGEYFCIY-HTYPDGAYTGR----IFLEVLESSVAEHGARF 138
G L + L+V DTGEY C+ T R +F E L+S AE G+
Sbjct: 3848 LRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTA 3907
Query: 139 QIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVE---GDLRRKSAGQ 186
+ + VV + + A R++ L+ + E DL+R+ G+
Sbjct: 3908 TLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGE 3958
Score = 33.5 bits (75), Expect = 0.17
Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 13/76 (17%)
Query: 33 ISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLG 92
+ E GG++ L C LS A+V W + L + F+ VA GP
Sbjct: 1818 VCGELGGTVTLACELSPACAEVV---WRCGNTQL---------RVGKRFQ-MVAEGPVRS 1864
Query: 93 LTLQSLTVNDTGEYFC 108
LT+ L D GEY C
Sbjct: 1865 LTVLGLRAEDAGEYVC 1880
Score = 32.3 bits (72), Expect = 0.39
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 29/89 (32%)
Query: 28 ETTGNISAEKGGSIILQCHLSSTTAQVT--------QVNWEQQDQLLAICNADLGWHISP 79
E ++ AE+G + LQC LS TA V Q N ++ +L C A+
Sbjct: 3894 EPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQG-CTAE------- 3945
Query: 80 SFKDRVAPGPGLGLTLQSLTVNDTGEYFC 108
L LQ L DTGEY C
Sbjct: 3946 -------------LVLQDLQREDTGEYTC 3961
Score = 30.4 bits (67), Expect = 1.5
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 20/86 (23%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVA 86
IE N A +G + +LQC L+S V W + + L DR +
Sbjct: 3541 IEDVKNQEAREGATAVLQCELNS----AAPVEWRKGSETL-------------RDGDRYS 3583
Query: 87 ---PGPGLGLTLQSLTVNDTGEYFCI 109
G L ++ L + DTGEY C+
Sbjct: 3584 LRQDGTKCELQIRGLAMADTGEYSCV 3609
Score = 29.3 bits (64), Expect = 3.3
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFK-DRV 85
++ ++SAE+ G++ LQC +S A V W + G + PS K D +
Sbjct: 2650 LKALDDLSAEERGTLALQCEVSDPEAHVV---WRKD-----------GVQLGPSDKYDFL 2695
Query: 86 APGPGLGLTLQSLTVNDTGEYFC 108
GL + ++ D G Y C
Sbjct: 2696 HTAGTRGLVVHDVSPEDAGLYTC 2718
Score = 28.5 bits (62), Expect = 5.6
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 12/100 (12%)
Query: 28 ETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAP 87
E + +AE G ++ L C ++ T V ++W + + + + P P
Sbjct: 6018 EELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAV---------QVDPHHILIEDP 6066
Query: 88 GPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYT-GRIFLEV 126
L L SLT D+G+Y C + T G+I ++V
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
>gi|4759066 sodium channel, voltage-gated, type II, beta [Homo
sapiens]
Length = 215
Score = 32.7 bits (73), Expect = 0.30
Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 81 FKDRV--APGPG---LGLTLQSLTVNDTGEYFCIYHTYPDGAYT-GRIFLEVLESSVAEH 134
F+DRV + P + + L+++ D G Y C PD G+I L+VL E
Sbjct: 95 FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPER 154
Query: 135 GARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLRRKSAGQEE 188
+ + ++GA + + V++VV R+KK ++ + DL+ + G+ +
Sbjct: 155 DSTVAV-IVGASVGGFLAVVILVLMVVKCVRRKKEQKLST--DDLKTEEEGKTD 205
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 32.7 bits (73), Expect = 0.30
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 14/102 (13%)
Query: 27 IETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVA 86
I+ N++ G +L C + S + W++ D+ + + R+
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDY--NLTWQRNDRDVRLAEPA-----------RIR 569
Query: 87 PGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVLE 128
L L L+S+ ND GEY C+ + G+ +FL V E
Sbjct: 570 TLANLSLELKSVKFNDAGEYHCMVSS-EGGSSAASVFLTVQE 610
Score = 30.8 bits (68), Expect = 1.1
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 14/85 (16%)
Query: 25 GTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDR 84
G + NIS + S+ L C S + + W + GW +S S R
Sbjct: 2388 GNHRSPENISVVEKNSVSLTCEASGIP--LPSITWFKD-----------GWPVSLSNSVR 2434
Query: 85 VAPGPGLGLTLQSLTVNDTGEYFCI 109
+ G G L L T+ D G+Y C+
Sbjct: 2435 ILSG-GRMLRLMQTTMEDAGQYTCV 2458
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 32.7 bits (73), Expect = 0.30
Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 4 CLLLIWAQGLRQAPLASGMMTGTI---ETTGNISAEKGGSIILQCHLSSTTAQVTQVNWE 60
CL+++ + L P + +G + N++ +G S L+C + +VT+V W
Sbjct: 13 CLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDD---RVTRVAWL 69
Query: 61 QQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHT 112
+ +L N W I P V + +Q++ V D G Y C T
Sbjct: 70 NRSTILYAGNDK--WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQT 119
>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
sapiens]
Length = 1336
Score = 32.7 bits (73), Expect = 0.30
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
Query: 96 QSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVLESSVAE 133
QSL + DTG Y C Y+ D +Y G + +VL+ V +
Sbjct: 284 QSLKIQDTGHYLCFYY---DASYRGSLLSDVLKIWVTD 318
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 32.3 bits (72), Expect = 0.39
Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 8/147 (5%)
Query: 26 TIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLA-ICNADLGWHISP--SFK 82
++ T N +A SI+ H S T ++W Q DQ I + +L ++ +
Sbjct: 426 SVNITTNQAAPSAVSIM---HQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYN 482
Query: 83 DRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPD-GAYTGRIFLEVLESSVAEHGARFQIP 141
P +T+Q L + T G Y+G+++ + + + + + ++P
Sbjct: 483 ATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLP 542
Query: 142 L-LGAMAATLVVICTAVIVVVALTRKK 167
L +G+ AA LV + V++ + R++
Sbjct: 543 LIIGSSAAGLVFLIAVVVIAIVCNRRR 569
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 32.3 bits (72), Expect = 0.39
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
Query: 17 PLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWH 76
P+ SG T + N++ +G S L+C + +VT+V W + +L N W
Sbjct: 23 PVRSGDATFP-KAMDNVTVRQGESATLRCTIDD---RVTRVAWLNRSTILYAGNDK--WS 76
Query: 77 ISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHT 112
I P V + +Q++ V D G Y C T
Sbjct: 77 IDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQT 112
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 32.0 bits (71), Expect = 0.50
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 12/77 (15%)
Query: 35 AEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLT 94
A++G SI L+C +S + +V+W + D L W + SF + VA LT
Sbjct: 6376 AKQGESIQLECKISGSPE--IKVSWFRNDSEL-----HESWKYNMSFINSVAL-----LT 6423
Query: 95 LQSLTVNDTGEYFCIYH 111
+ + D+G+Y C H
Sbjct: 6424 INEASAEDSGDYICEAH 6440
>gi|5174411 CD5 molecule-like [Homo sapiens]
Length = 347
Score = 32.0 bits (71), Expect = 0.50
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 58 NWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLG 92
NW +++ + G +SPSF+DR GPG+G
Sbjct: 272 NWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVG 306
>gi|211904177 hypothetical protein LOC388336 [Homo sapiens]
Length = 551
Score = 32.0 bits (71), Expect = 0.50
Identities = 17/55 (30%), Positives = 27/55 (49%)
Query: 76 HISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEVLESS 130
H+ PS++ V P +L+ LT + EY+ PD A G + L V++ S
Sbjct: 346 HLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMS 400
>gi|90903245 CD200 antigen isoform b [Homo sapiens]
Length = 294
Score = 31.6 bits (70), Expect = 0.66
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 11/93 (11%)
Query: 43 LQCHLSSTTAQVTQVNWEQQDQL----LAICNADLGWHISPSFKDRVAPGPGLGL----- 93
L+C L + + V W+++ + + + + G I P++KD++ LGL
Sbjct: 74 LKCSLQNAQEALI-VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQ-LGLQNSTI 131
Query: 94 TLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEV 126
T ++T+ D G Y C+++T+ G +G L V
Sbjct: 132 TFWNITLEDEGCYMCLFNTFGFGKISGTACLTV 164
>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
Length = 269
Score = 31.6 bits (70), Expect = 0.66
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 11/93 (11%)
Query: 43 LQCHLSSTTAQVTQVNWEQQDQL----LAICNADLGWHISPSFKDRVAPGPGLGL----- 93
L+C L + + V W+++ + + + + G I P++KD++ LGL
Sbjct: 49 LKCSLQNAQEALI-VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQ-LGLQNSTI 106
Query: 94 TLQSLTVNDTGEYFCIYHTYPDGAYTGRIFLEV 126
T ++T+ D G Y C+++T+ G +G L V
Sbjct: 107 TFWNITLEDEGCYMCLFNTFGFGKISGTACLTV 139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,154,662
Number of Sequences: 37866
Number of extensions: 458529
Number of successful extensions: 2162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 2035
Number of HSP's gapped (non-prelim): 192
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.