Guide to the Human Genome
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Name: TIGIT Sequence: fasta or formatted (244aa) NCBI GI: 27883876
Description:

T cell immunoreceptor with Ig and ITIM domains

Not currently referenced in the text

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.8         24           2
 C cysteine            3.7          9           1
 D aspartate           3.3          8           1
 E glutamate           6.1         15           2
 F phenylalanine       2.9          7           2
 G glycine             9.4         23           2
 H histidine           2.5          6           1
 I isoleucine          5.3         13           2
 K lysine              2.5          6           3
 L leucine            10.7         26           3
 M methionine          1.6          4           2
 N asparagine          2.5          6           1
 P proline             4.5         11           2
 Q glutamine           5.3         13           2
 R arginine            4.5         11           2
 S serine              7.8         19           2
 T threonine           7.0         17           2
 V valine              6.1         15           3
 W tryptophan          2.0          5           1
 Y tyrosine            2.5          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   T cell immunoreceptor with Ig and ITIM domains [Homo... 
PVRL4                 0.057   poliovirus receptor-related 4 
PVRL2                 0.034   poliovirus receptor related 2 isoform alpha precursor...
PVRL2                 0.034   poliovirus receptor related 2 isoform delta precurs...
PVRL1                 0.032   poliovirus receptor-related 1 isoform 3 
PVRL1                 0.032   poliovirus receptor-related 1 isoform 2 
PVRL1                 0.032   poliovirus receptor-related 1 isoform 1 
PVRL3                 0.032   poliovirus receptor-related 3 
PVR                   0.032   poliovirus receptor isoform delta 
PVR                   0.032   poliovirus receptor isoform gamma 
PVR                   0.032   poliovirus receptor isoform beta 
PVR                   0.032   poliovirus receptor isoform alpha 
IGSF11                0.027   immunoglobulin superfamily, member 11 isoform a [Hom...
CD96                  0.023   CD96 antigen isoform 1 precursor 
CD96                  0.023   CD96 antigen isoform 2 precursor 
IGSF11                0.023   immunoglobulin superfamily, member 11 isoform b [Hom...
F11R                  0.021   F11 receptor precursor 
OBSCN                 0.021   obscurin, cytoskeletal calmodulin and titin-interact...
OBSCN                 0.021   obscurin, cytoskeletal calmodulin and titin-interac...
SCN2B                 0.017   sodium channel, voltage-gated, type II, beta 
HMCN1                 0.017   hemicentin 1 
OPCML                 0.017   opioid binding protein/cell adhesion molecule-like is...
IGSF1                 0.017   immunoglobulin superfamily, member 1 isoform 1 [Homo...
EPHB2                 0.015   ephrin receptor EphB2 isoform 2 precursor 
OPCML                 0.015   opioid binding protein/cell adhesion molecule-like i...
TTN                   0.015   titin isoform N2-A 
CD5L                  0.015   CD5 molecule-like 
FLJ45455              0.015   hypothetical protein LOC388336 
CD200                 0.015   CD200 antigen isoform b 
CD200                 0.015   CD200 antigen isoform a precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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