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Search of human proteins with 27477138
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27477138 zinc finger antiviral protein isoform 2 [Homo
sapiens]
(699 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens] 1441 0.0
gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens] 1440 0.0
gi|18087829 zinc finger CCCH-type, antiviral 1-like [Homo sapiens] 179 8e-45
gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens] 167 4e-41
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 49 2e-05
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 44 5e-04
gi|60097902 filaggrin [Homo sapiens] 37 0.062
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 36 0.11
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 36 0.14
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 36 0.14
gi|83367077 mucin 16 [Homo sapiens] 35 0.24
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 35 0.31
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 35 0.31
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 35 0.31
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 35 0.31
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP... 33 0.69
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 33 0.69
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ... 32 1.5
gi|167736355 mucin 4 isoform a [Homo sapiens] 32 2.0
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ... 32 2.6
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ... 32 2.6
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ... 32 2.6
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 31 3.4
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 31 4.5
gi|33563376 TBC1 domain family, member 16 [Homo sapiens] 31 4.5
gi|226246533 TOX high mobility group box family member 3 isoform... 30 5.8
gi|226054295 TOX high mobility group box family member 3 isoform... 30 5.8
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 30 5.8
gi|115298674 nidogen 1 precursor [Homo sapiens] 30 5.8
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap... 30 7.6
>gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]
Length = 699
Score = 1441 bits (3731), Expect = 0.0
Identities = 699/699 (100%), Positives = 699/699 (100%)
Query: 1 MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60
MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
Sbjct: 1 MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60
Query: 61 TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120
TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV
Sbjct: 61 TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120
Query: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180
LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG
Sbjct: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180
Query: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240
NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN
Sbjct: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240
Query: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300
MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL
Sbjct: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300
Query: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360
GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK
Sbjct: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360
Query: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420
SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ
Sbjct: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420
Query: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480
DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD
Sbjct: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480
Query: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540
DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM
Sbjct: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540
Query: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600
LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN
Sbjct: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600
Query: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660
SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE
Sbjct: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660
Query: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPE 699
LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPE
Sbjct: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPE 699
>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
Length = 902
Score = 1440 bits (3728), Expect = 0.0
Identities = 698/699 (99%), Positives = 699/699 (100%)
Query: 1 MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60
MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
Sbjct: 1 MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60
Query: 61 TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120
TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV
Sbjct: 61 TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120
Query: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180
LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG
Sbjct: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180
Query: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240
NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN
Sbjct: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240
Query: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300
MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL
Sbjct: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300
Query: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360
GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK
Sbjct: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360
Query: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420
SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ
Sbjct: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420
Query: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480
DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD
Sbjct: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480
Query: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540
DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM
Sbjct: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540
Query: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600
LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN
Sbjct: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600
Query: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660
SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE
Sbjct: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660
Query: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPE 699
LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGP+
Sbjct: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPD 699
>gi|18087829 zinc finger CCCH-type, antiviral 1-like [Homo sapiens]
Length = 300
Score = 179 bits (454), Expect = 8e-45
Identities = 98/247 (39%), Positives = 141/247 (57%), Gaps = 24/247 (9%)
Query: 1 MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLE------- 53
MA+P VC F+TK+LCAHGGRM L L + LSE +L +VLQ AGP+RF++ E
Sbjct: 1 MAEPTVCSFLTKVLCAHGGRMFLKDLRGHVELSEARLRDVLQRAGPERFLLQEVETQEGL 60
Query: 54 -----------TGGEAGITRSVVATTRARVC---RRKYCQRPCDNLHLCKLNLLGRCNYS 99
GG VVA + R+C +R CQ CD LH C+ ++LG+C +
Sbjct: 61 GDAEAEAAAGAVGGGGTSAWRVVAVSSVRLCARYQRGECQ-ACDQLHFCRRHMLGKCP-N 118
Query: 100 QSERNLCKYSHEVLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSY-KGEGR 158
+ + C SH++ + N +VLK+H L GLN+ +L +LLLQ+DP +PE+C Y KGE
Sbjct: 119 RDCWSTCTLSHDIHTPVNMQVLKSHGLFGLNENQLRILLLQNDPCLLPEVCLLYNKGEAL 178
Query: 159 QQICNQQPPCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDI 218
CN + C++ H+C F +G C+ C RSH L+ L ++++ GLN V N Q I
Sbjct: 179 YGYCNLKDKCNKFHVCKSFVKGECKLQTCKRSHQLIHAASLKLLQDQGLNIPSVVNFQII 238
Query: 219 CNSKHMQ 225
KH++
Sbjct: 239 STYKHIK 245
>gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]
Length = 701
Score = 167 bits (422), Expect = 4e-41
Identities = 91/219 (41%), Positives = 120/219 (54%), Gaps = 17/219 (7%)
Query: 491 DSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFE 550
DS V+ T S+ + ++ICL H+ K C C +VHFHLPYRWQ L W D +
Sbjct: 257 DSSGSVSPNTLSQ---EEGDQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDRGKWEDLD 313
Query: 551 HMETIEKGYCNPGIH--LCSVG-----SYTINFRVMSCDSFPIRRLSTPSSVTKPANSVF 603
+ME IE+ YCNP I LCS S+ +NF M+ + RRLST SSVTKP + +
Sbjct: 314 NMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMTYGATQARRLSTASSVTKPPHFIL 373
Query: 604 TTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQS-CPRG------VVPFQAGS 656
TT WIWYW +E G+W +YG + + V SS +E Y + C G + FQAG
Sbjct: 374 TTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGK 433
Query: 657 RNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMK 695
NYEL F+ +Q N+ T K V RRP +V V M+
Sbjct: 434 HNYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQ 472
Score = 136 bits (343), Expect = 6e-32
Identities = 84/238 (35%), Positives = 128/238 (53%), Gaps = 14/238 (5%)
Query: 1 MADPEVCCFITKILCAHGGRMALDALLQEI--ALSEPQLCEVLQVAGPDRFVVLETGGEA 58
MA V +T++LCA GG + L L + + LS L +L+ G RFVV G A
Sbjct: 1 MAQAGVVGEVTQVLCAAGGALELPELRRRLRMGLSADALERLLRQRG--RFVVAVRAGGA 58
Query: 59 GIT--RSVVATTRARVCRRKYCQRP-----CDNLHLCKLNLLGRCNYSQSERNLCKYSHE 111
R V+A + R+CR +P C LHLC+ + G C + ++ +N C+ SH
Sbjct: 59 AAAPERVVLAASPLRLCRAHQGSKPGCVGLCAQLHLCRFMVYGACKFLRAGKN-CRNSHS 117
Query: 112 VLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSY-KGEGRQQICNQQPPCSR 170
+ +E N VL+ H + L+ EL LL Q+DP+ +PEIC+ Y KG+G C Q C +
Sbjct: 118 LTTEHNLSVLRTHGVDHLSYNELCQLLFQNDPWLLPEICQHYNKGDGPHGSCAFQKQCIK 177
Query: 171 LHICDHFTRGNCRF-PNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKN 227
LHIC +F +G C+F +C RSH+ + + L + + G++ D+V + I + H KN
Sbjct: 178 LHICQYFLQGECKFGTSCKRSHDFSNSENLEKLEKLGMSSDLVSRLPTIYRNAHDIKN 235
>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
sapiens]
Length = 657
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 511 EICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKT--WTDF--EHMETIEKGYCNPGIHL 566
EIC+D L C C K H LPY WQ+ T W + E +E+ YCNP
Sbjct: 241 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR 300
Query: 567 CSV----GSYTINFRVM----SCDSFPIRRLSTPSSVTKPANSVFTTKWIWYWKNESGTW 618
+ + + M + + +RRLSTP S NS++ T W ++ ++ G W
Sbjct: 301 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPS--SNVNSIYHTVWKFFCRDHFG-W 357
Query: 619 IQYGE 623
+Y E
Sbjct: 358 REYPE 362
>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
sapiens]
Length = 338
Score = 43.9 bits (102), Expect = 5e-04
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 605 TKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQ 664
T+W W++ E G W + + D +V S +E +++ P G + F +Y++ F
Sbjct: 32 TQWGWFYLAECGKWHMF--QPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA 89
Query: 665 GMIQTNIASKTQKDVIRRP 683
M Q N+ + Q+ + R P
Sbjct: 90 EMKQMNLTTGKQRLIKRAP 108
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 37.0 bits (84), Expect = 0.062
Identities = 58/247 (23%), Positives = 84/247 (34%), Gaps = 18/247 (7%)
Query: 235 SSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLT 294
SS R+ +R S S+ +G E + S SA P Q SH+ S
Sbjct: 2352 SSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA--GPHQQSHQESTRGRSAGRSG 2409
Query: 295 RK--FTYLGSQDRARPPSGSSKATDLGGTS-----QAGTSQRFLENGSQEDLLHGNPGST 347
R F Y S + T GG QA S R + +D +HG+PGS
Sbjct: 2410 RSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS- 2468
Query: 348 YLASNSTSAPNWKSLTSWTNDQGARRK-TVFSPTLPAARSSLGSLQTPEAVTT--RKGTG 404
+S +++ L + G+ T A+ GS + G G
Sbjct: 2469 --SSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDG 2526
Query: 405 LLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQD 464
S R S + ++G T S + S S GH E S +
Sbjct: 2527 SRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSE---RW 2583
Query: 465 AGPASRD 471
+G ASR+
Sbjct: 2584 SGSASRN 2590
Score = 35.0 bits (79), Expect = 0.24
Identities = 54/248 (21%), Positives = 79/248 (31%), Gaps = 19/248 (7%)
Query: 230 GPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAP 289
G R SS R+ +R S S+ +G E + S SA P A +
Sbjct: 1374 GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGE 1433
Query: 290 VDDLTRKFTYLGSQDRARPPSGSSKATDLGGT-----SQAGTSQRFLENGSQEDLLHGNP 344
+R F Y S + A GG QA S R + +D + G+P
Sbjct: 1434 SSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHP 1493
Query: 345 GSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRK--- 401
G S+ S + D+ S T P RS Q+ +R+
Sbjct: 1494 G-------SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRN 1546
Query: 402 ----GTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREI 457
G G S R + + + + G T S++ S GH E
Sbjct: 1547 EEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSED 1606
Query: 458 SSPRIQDA 465
S R + A
Sbjct: 1607 SERRSESA 1614
Score = 30.0 bits (66), Expect = 7.6
Identities = 56/254 (22%), Positives = 86/254 (33%), Gaps = 22/254 (8%)
Query: 230 GPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAP 289
G R SS + R S S+ +G E + S SA P Q SH+ S
Sbjct: 1698 GRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQA--GPHQQSHQESTRGQS 1755
Query: 290 VDDLTRKFTYL----------GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDL 339
+ R ++L + R P +G + + QA S R + +D
Sbjct: 1756 GERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSR---HEQARDSSRHSASQEGQDT 1812
Query: 340 LHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTT 399
+ G+PGS+ + +S+ S + T +R GS
Sbjct: 1813 IRGHPGSS--RGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRN 1870
Query: 400 RK--GTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREI 457
K G G S R S + + + G T S++ S S GH E
Sbjct: 1871 EKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSED 1930
Query: 458 SSPRIQDAGPASRD 471
S + +G ASR+
Sbjct: 1931 SE---RWSGSASRN 1941
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 36.2 bits (82), Expect = 0.11
Identities = 58/243 (23%), Positives = 89/243 (36%), Gaps = 51/243 (20%)
Query: 229 PGPRA---PSSHRRNMAYRARSKS-----RDRFFQGSQEFLASASASAERSCTPSPDQIS 280
P P+A P+ R + R S+S RD QGS + S + +R+ T
Sbjct: 523 PEPKAHYEPADRAREVPVRTTSRSPVLSRRDSPLQGSGQ---QNSQAGQRNST------- 572
Query: 281 HRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGT-------SQAGTSQRFLEN 333
+S+E + + K RP SGSS + G+ SQ+G+ +RF
Sbjct: 573 --SSIEPRLLWERVEKLV-------PRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVR 623
Query: 334 GSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQT 393
S + G+P N+ P K K VF P PA L +L
Sbjct: 624 SSSKS--EGSPSQRL--ENAVKKPEDK-------------KEVFRPLKPAGEVDLTALAK 666
Query: 394 PEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSG 453
+DY + +SGT D + + AD + TR+ + + S+G
Sbjct: 667 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG 726
Query: 454 HRE 456
E
Sbjct: 727 ETE 729
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 35.8 bits (81), Expect = 0.14
Identities = 60/284 (21%), Positives = 105/284 (36%), Gaps = 31/284 (10%)
Query: 231 PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
PR+P++ + + S + S+ +A + + TP + S +
Sbjct: 973 PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 1032
Query: 291 DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
D L T G + SS +TD T+ + S L G + H NPGST+
Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTD---TALSPGSTTALSFGQESTTFHSNPGSTH 1089
Query: 349 --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
L +ST++ ++ + +T SP T P + + QT A T +
Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 1149
Query: 404 GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
++ + +S T PG T T ST+SGH E S
Sbjct: 1150 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 1194
Query: 459 SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
SP P+S +GR + R++ + ++ + +T++
Sbjct: 1195 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 1237
Score = 35.8 bits (81), Expect = 0.14
Identities = 65/302 (21%), Positives = 108/302 (35%), Gaps = 45/302 (14%)
Query: 228 PPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLED 287
P P PS ++ + +S D S S+ S E S + S +H + D
Sbjct: 2511 PGSPTTPSLSEKSTTFYTSPRSPDATL--SPATTTSSGVSEESSTSHSQPGSTHTTAFPD 2568
Query: 288 APVDD-----LTRKFTYLGSQDRARPP-----SGSSKATDLGGTSQAGT-------SQRF 330
+ T + GS D P SG S+ + +S T S
Sbjct: 2569 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTA 2628
Query: 331 LENGSQEDLLHGNPGSTY--LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAAR 385
L G + H +PGST+ L +ST++ ++ + +T SP T P +
Sbjct: 2629 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQ 2688
Query: 386 SSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSL 445
+ QT A T + ++ + +S T PG T T
Sbjct: 2689 GESTTFQTHPASTHTTPSPPSTATAPV--EESTTYHRSPGS-------------TPTTHF 2733
Query: 446 NYKSTSSGHRE-----ISSPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTT 500
ST+SGH E SSP P+S +GR + R++ + ++ + +T
Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGST 2792
Query: 501 SS 502
++
Sbjct: 2793 TT 2794
Score = 35.8 bits (81), Expect = 0.14
Identities = 60/284 (21%), Positives = 106/284 (37%), Gaps = 31/284 (10%)
Query: 231 PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
PR+P++ + + S + S+ +A + + TP + S +
Sbjct: 3613 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 3672
Query: 291 DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
D L T GS + SS +TD T+ + S L G + H +PGST+
Sbjct: 3673 DTTLLPASTTTSGSSQESTTSHSSSGSTD---TALSPGSTTALSFGQESTTFHSSPGSTH 3729
Query: 349 --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
L +ST++ ++ + +T SP T P + + QT A T +
Sbjct: 3730 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 3789
Query: 404 GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
++ + +S T PG T T ST+SGH E S
Sbjct: 3790 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 3834
Query: 459 SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
SP P+S +GR + R++ + ++ + +T++
Sbjct: 3835 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 3877
Score = 32.0 bits (71), Expect = 2.0
Identities = 58/284 (20%), Positives = 104/284 (36%), Gaps = 31/284 (10%)
Query: 231 PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
PR+P++ + + S + S+ +A + + TP + S +
Sbjct: 2056 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2115
Query: 291 DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
D L T G + S +TD T+ + S L G + H +PGST+
Sbjct: 2116 DTTLLPASTTTSGPSQESTTSHSSPGSTD---TALSPGSTTALSFGQESTTFHSSPGSTH 2172
Query: 349 --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
L +ST++ ++ + +T SP T P + + QT A T +
Sbjct: 2173 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 2232
Query: 404 GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
++ + +S T PG T T ST+SGH E S
Sbjct: 2233 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 2277
Query: 459 SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
SP P+S +GR + R++ + ++ + +T++
Sbjct: 2278 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 2320
Score = 30.0 bits (66), Expect = 7.6
Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 22/159 (13%)
Query: 315 ATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRK 374
+T + G SQ T+ + + L +PG+T +S + + S +T
Sbjct: 326 STTMPGVSQESTASHSIPGSTDTTL---SPGTTTPSSLGPESTTFHSSPGYTKTTRLPDN 382
Query: 375 TVFSPTLPAA---RSSLGSLQT---PEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLF 428
T S L A+ SS GS T P + TT +G + ++D P P
Sbjct: 383 TTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSW------PSSKDTSPAPSG 436
Query: 429 NNNAD-------GVATDITSTRSLNYKSTSSGHREISSP 460
+A + T T + ST+ GH E S+P
Sbjct: 437 TTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTP 475
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 35.8 bits (81), Expect = 0.14
Identities = 60/284 (21%), Positives = 105/284 (36%), Gaps = 31/284 (10%)
Query: 231 PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
PR+P++ + + S + S+ +A + + TP + S +
Sbjct: 460 PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 519
Query: 291 DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
D L T G + SS +TD T+ + S L G + H NPGST+
Sbjct: 520 DTTLLPASTTTSGPSQESTTSHSSSGSTD---TALSPGSTTALSFGQESTTFHSNPGSTH 576
Query: 349 --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
L +ST++ ++ + +T SP T P + + QT A T +
Sbjct: 577 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 636
Query: 404 GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
++ + +S T PG T T ST+SGH E S
Sbjct: 637 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 681
Query: 459 SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
SP P+S +GR + R++ + ++ + +T++
Sbjct: 682 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 724
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 35.0 bits (79), Expect = 0.24
Identities = 61/251 (24%), Positives = 91/251 (36%), Gaps = 26/251 (10%)
Query: 230 GPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAP 289
G + S+ + + +S + G+ E + AS+ R+ P PD H D
Sbjct: 6658 GLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPD---HSTESPDIS 6714
Query: 290 VDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYL 349
+ + LG + + + LG TSQ GT S H +
Sbjct: 6715 TEVIPSLPISLGITESSNMTIITRTGPPLGSTSQ-GTFTLDTPTTSSRAGTHSMATQEFP 6773
Query: 350 ASNSTSAPNWK-SLTSWTNDQGARRKTVFSPTL---PAARSSLGSLQTPEAVTTRKG--T 403
S T+ N + SWT KT FS +L PA S S P+ + T T
Sbjct: 6774 HSEMTTVMNKDPEILSWTIPPSIE-KTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMT 6832
Query: 404 GLLSSDYRIINGKSGTQD----IQPGPLFNNNADGVATD-----------ITSTRSLNYK 448
LL+ + GT P L + + + + TD TST + N +
Sbjct: 6833 SLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVE 6892
Query: 449 STSSGHREISS 459
+TSSGH SS
Sbjct: 6893 TTSSGHGSQSS 6903
Score = 32.7 bits (73), Expect = 1.2
Identities = 71/344 (20%), Positives = 119/344 (34%), Gaps = 52/344 (15%)
Query: 206 GLNPDVVQN--IQDICNSKHMQKNPPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLAS 263
G +PDV I + + P G + +S + S S E L +
Sbjct: 3441 GASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRA 3500
Query: 264 ASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQ 323
++ + P+ +S +S + + D+T P G S GT+
Sbjct: 3501 NVSAVKSDIAPTAGHLSQTSSPAEVSILDVT-----------TAPTPGISTTITTMGTNS 3549
Query: 324 AGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLT---SWT-NDQGARRKTVFSP 379
T+ E G + P + +++ W S SWT D + K SP
Sbjct: 3550 ISTTTPNPEVGMST--MDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSP 3607
Query: 380 ---------TLPAARSSLGSLQTPEAVTTRKGTGLL--SSDYRIINGKSGTQDIQPGPLF 428
+ A+ + L S+ TP T GT L+ SSD + ++ T + P
Sbjct: 3608 GTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSP-- 3665
Query: 429 NNNADGVATDITSTRSLNYKSTSSGHREIS---SPRIQDAGPASRDVQATGRIADDADPR 485
+D A+ ST S + + S +S +P +A + +T + DP
Sbjct: 3666 ---SDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPN 3722
Query: 486 VAL--------------VNDSLSDVTSTTSSRVDDHDSEEICLD 515
L SLS T+TTS+ +E+ L+
Sbjct: 3723 TPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLE 3766
Score = 30.4 bits (67), Expect = 5.8
Identities = 36/152 (23%), Positives = 56/152 (36%), Gaps = 21/152 (13%)
Query: 309 PSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPN-----WKSLT 363
PS S T T G + +GS PG L++ + S P+ + S T
Sbjct: 10280 PSLSEAMTSFATT---GVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSST 10336
Query: 364 SWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQ 423
T D S T+PA S TP V T GT +++ R++ + Q
Sbjct: 10337 FTTTD---------SSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQ 10387
Query: 424 PGPLFNNNADGVATDITSTRSLNYKSTSSGHR 455
PG + D T S+ + +S ++
Sbjct: 10388 PG----RTSSSPILDTRMTESVELGTVTSAYQ 10415
Score = 29.6 bits (65), Expect = 9.9
Identities = 60/225 (26%), Positives = 81/225 (36%), Gaps = 48/225 (21%)
Query: 267 SAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARP----PSGSSKATDLG--- 319
S+ R+ P P Q + + + L T S + P PSGS+ L
Sbjct: 6990 SSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDT 7049
Query: 320 --GTSQAGT----SQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARR 373
SQA T +QRF + L+ PG S S S N SL S +
Sbjct: 7050 STTKSQAKTHSTLTQRF-PHSEMTTLMSRGPGDMSWQS-SPSLENPSSLPSLLSLPATTS 7107
Query: 374 KTVFSPTLPAARSS----LGSLQT-------------PEAVTTRKGTGLLSSDYRIINGK 416
S TLP SS + SL T PE VT+ +SD R+ GK
Sbjct: 7108 PPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGK 7167
Query: 417 --SGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISS 459
+ T+ + P T+T + N + SSGH SS
Sbjct: 7168 DTTNTEAVHPS--------------TNTAASNVEIPSSGHESPSS 7198
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 34.7 bits (78), Expect = 0.31
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 11/85 (12%)
Query: 604 TTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSF 663
+ W W+ + SG W Y NS +DS++ V F AG R Y + F
Sbjct: 1614 SNNWRWF-DDRSGRWCSYSASN----NSTIDSAWKSG------ETSVRFTAGRRRYTVQF 1662
Query: 664 QGMIQTNIASKTQKDVIRRPTFVPQ 688
M+Q N + ++ V+ VP+
Sbjct: 1663 TTMVQVNEETGNRRPVMLTLLRVPR 1687
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 34.7 bits (78), Expect = 0.31
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%)
Query: 307 RPPSGSSKATDLGGT-------SQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNW 359
RP SGSS + G+ SQ+G+ +RF S + G+P N+ P
Sbjct: 644 RPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKS--EGSPSQRL--ENAVKKPED 699
Query: 360 KSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGT 419
K K VF P PA L +L +DY + +SGT
Sbjct: 700 K-------------KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGT 746
Query: 420 QDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE 456
D + + AD + TR+ + + S+G E
Sbjct: 747 TDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETE 783
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 34.7 bits (78), Expect = 0.31
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%)
Query: 307 RPPSGSSKATDLGGT-------SQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNW 359
RP SGSS + G+ SQ+G+ +RF S + G+P N+ P
Sbjct: 752 RPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKS--EGSPSQRL--ENAVKKPED 807
Query: 360 KSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGT 419
K K VF P PA L +L +DY + +SGT
Sbjct: 808 K-------------KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGT 854
Query: 420 QDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE 456
D + + AD + TR+ + + S+G E
Sbjct: 855 TDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETE 891
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 34.7 bits (78), Expect = 0.31
Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 21/139 (15%)
Query: 232 RAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVD 291
R+ S RR +R+RS R + ++ +R T SP + SHR S +
Sbjct: 213 RSDSGSRRKRRHRSRSSKCKRKEKNKEK---------KRPHTESPGRRSHRHSSGSSHSP 263
Query: 292 DLTRKFTYLGSQDRARPP------------SGSSKATDLGGTSQAGTSQRFLENGSQEDL 339
L+ ++ S R P S S++ G S G+ QR +G +
Sbjct: 264 SLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGA 323
Query: 340 LHGNPGSTYLASNSTSAPN 358
G PGS + + S+P+
Sbjct: 324 HGGRPGSAHSPPDKPSSPS 342
>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 1 [Homo sapiens]
Length = 759
Score = 33.5 bits (75), Expect = 0.69
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
Query: 252 RFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV-DDLTRKFTYLGSQDRARPPS 310
R Q + L S +++ + T + Q+ + D L R+ + GS+ + +
Sbjct: 459 RIMQKKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYET 518
Query: 311 GSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQG 370
GS + L G + R E+ + + G + L ++S+S P++ S SW+ D+
Sbjct: 519 GSGQKPYL----PMGEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDES 574
Query: 371 ARR 373
ARR
Sbjct: 575 ARR 577
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 33.5 bits (75), Expect = 0.69
Identities = 48/192 (25%), Positives = 73/192 (38%), Gaps = 17/192 (8%)
Query: 230 GPRAPSSHRRNMAYRARSK--SRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLED 287
G + S R+ +Y + S SR F GS+ S S+S S TPSP + S R E
Sbjct: 566 GSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP 625
Query: 288 APVDDLTRKFTYLGSQDRARPPSGSS------KATDLGGTSQAGTSQRFLENGSQEDLLH 341
AP + + PP + + T G +A +R + L
Sbjct: 626 APPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLS 685
Query: 342 GN---PGSTYLASN----STSAPNWKSLTSWTNDQGARRKTVFSPTLP--AARSSLGSLQ 392
G+ GS+Y S+ S S + S++S T+ + A+ S S +
Sbjct: 686 GSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSR 745
Query: 393 TPEAVTTRKGTG 404
+P TRK G
Sbjct: 746 SPAPAQTRKEKG 757
>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
sapiens]
Length = 709
Score = 32.3 bits (72), Expect = 1.5
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 12/103 (11%)
Query: 237 HRRNMAYRARSKSRDRFFQGSQEF--------LASASASAERSCTPSPDQISHRASLEDA 288
H + +R +SR+R Q SQ+ ++ + E+ +P ++S+ SL D
Sbjct: 82 HGLKHLFHSRRRSREREHQTSQDSQQHQQQQGMSDHDSPDEKERSPEMHRVSYAMSLHDL 141
Query: 289 PVDDLTRKFTYLGSQDRARP--PSGSSKATDLGGTSQAGTSQR 329
P F + Q R+RP G+S + GG S +S+R
Sbjct: 142 PARPTA--FNRVLQQIRSRPSIKRGASLHSSSGGGSSGSSSRR 182
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 32.0 bits (71), Expect = 2.0
Identities = 44/199 (22%), Positives = 77/199 (38%), Gaps = 17/199 (8%)
Query: 261 LASASASAERSCTPSPDQISHRASLEDA---PVDDLTRKFTYLGSQDRARPPSGSSKATD 317
+ AS+ + TP P + AS D PV D T S +A P T
Sbjct: 3459 VTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTD-----TSSASTGQATP----LPVTS 3509
Query: 318 LGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVF 377
L S T+ + + S H P S++++ + + T+ + T
Sbjct: 3510 LSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPL 3569
Query: 378 SPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNN--ADGV 435
T+P++ SS + P T+ TG ++ + + T + P P+ + + + G
Sbjct: 3570 PVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGH 3629
Query: 436 ATDITSTRSLNYKSTSSGH 454
AT + T + S S+GH
Sbjct: 3630 ATPLLVT---DASSVSTGH 3645
>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
sapiens]
Length = 355
Score = 31.6 bits (70), Expect = 2.6
Identities = 46/175 (26%), Positives = 66/175 (37%), Gaps = 22/175 (12%)
Query: 271 SCTPSPD-------QISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATD------ 317
SC PSP ++ + S P +GS +R PS + T
Sbjct: 30 SCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPGPP 89
Query: 318 -LGGTSQAGTSQRFLENGSQEDLLHGNP---GSTYLASNSTSAPNWKSLTSWTNDQGARR 373
G + A + + L S+ D P G TY A S LT + + + R
Sbjct: 90 HQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGG-GLTKYNSAHSSSR 148
Query: 374 KTVFSPTLPAAR--SSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGP 426
V P LP+ R +S G PE+ R+G G S+ R G T+ +PGP
Sbjct: 149 --VPRPRLPSQRRGASCGLGPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGP 201
>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
sapiens]
Length = 355
Score = 31.6 bits (70), Expect = 2.6
Identities = 46/175 (26%), Positives = 66/175 (37%), Gaps = 22/175 (12%)
Query: 271 SCTPSPD-------QISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATD------ 317
SC PSP ++ + S P +GS +R PS + T
Sbjct: 30 SCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPGPP 89
Query: 318 -LGGTSQAGTSQRFLENGSQEDLLHGNP---GSTYLASNSTSAPNWKSLTSWTNDQGARR 373
G + A + + L S+ D P G TY A S LT + + + R
Sbjct: 90 HQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGG-GLTKYNSAHSSSR 148
Query: 374 KTVFSPTLPAAR--SSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGP 426
V P LP+ R +S G PE+ R+G G S+ R G T+ +PGP
Sbjct: 149 --VPRPRLPSQRRGASCGLGPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGP 201
>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
sapiens]
Length = 355
Score = 31.6 bits (70), Expect = 2.6
Identities = 46/175 (26%), Positives = 66/175 (37%), Gaps = 22/175 (12%)
Query: 271 SCTPSPD-------QISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATD------ 317
SC PSP ++ + S P +GS +R PS + T
Sbjct: 30 SCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPGPP 89
Query: 318 -LGGTSQAGTSQRFLENGSQEDLLHGNP---GSTYLASNSTSAPNWKSLTSWTNDQGARR 373
G + A + + L S+ D P G TY A S LT + + + R
Sbjct: 90 HQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGG-GLTKYNSAHSSSR 148
Query: 374 KTVFSPTLPAAR--SSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGP 426
V P LP+ R +S G PE+ R+G G S+ R G T+ +PGP
Sbjct: 149 --VPRPRLPSQRRGASCGLGPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGP 201
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 31.2 bits (69), Expect = 3.4
Identities = 50/256 (19%), Positives = 100/256 (39%), Gaps = 9/256 (3%)
Query: 247 SKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRA 306
S S D S +++S S++ S + + + S + D+ D + S +
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS------DSSNSN 722
Query: 307 RPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWT 366
S SS ++D +S + S ++ + D + S S+ +S + S +S +
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 367 NDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGP 426
+D + S + S S + ++ + SSD + S + +
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842
Query: 427 LFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIADDADPRV 486
++++DG +D +S RS + S+ S SS + S D + +D +D
Sbjct: 843 DSSDSSDGSDSD-SSNRSDSSNSSDSSDSSDSSNSSDSSD--SSDSNESSNSSDSSDSSN 899
Query: 487 ALVNDSLSDVTSTTSS 502
+ +DS S+ SS
Sbjct: 900 SSDSDSSDSSNSSDSS 915
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 30.8 bits (68), Expect = 4.5
Identities = 41/185 (22%), Positives = 74/185 (40%), Gaps = 21/185 (11%)
Query: 232 RAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVD 291
R+PS R+ R+ +K RDR SQ S +S +PS ++ R +P
Sbjct: 525 RSPSKERQRRQSRSPNKERDR----SQSRSPSEEREHRQSRSPSKERDRRRWR---SPSK 577
Query: 292 DLTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLAS 351
+ R+ + S++R S S G + +S+ + S+ GN + +S
Sbjct: 578 ERERRQSRSSSEERDHSRSRSPNKQS-GYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSS 636
Query: 352 NSTS--------APNWK----SLTSWTNDQGARRKTVFSP-TLPAARSSLGSLQTPEAVT 398
+ +P+WK +S + ++ + + SP T P+ +L + T
Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADAT 696
Query: 399 TRKGT 403
T K T
Sbjct: 697 TSKAT 701
>gi|33563376 TBC1 domain family, member 16 [Homo sapiens]
Length = 767
Score = 30.8 bits (68), Expect = 4.5
Identities = 18/50 (36%), Positives = 22/50 (44%)
Query: 580 SCDSFPIRRLSTPSSVTKPANSVFTTKWIWYWKNESGTWIQYGEEKDKRK 629
+C F IRR PSS T P S++ + W N Q EE RK
Sbjct: 370 TCMQFSIRRPKLPSSETHPEESMYKRLGVSAWLNHLNELGQVEEEYKLRK 419
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 30.4 bits (67), Expect = 5.8
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 25/161 (15%)
Query: 263 SASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARPPSG-------SSKA 315
S S A +S TPSP +S+ + D+ R + RA P SG K
Sbjct: 194 SPSPPASKSATPSPS-----SSINEEDADEANRAI----GEKRAAPDSGKKPKTPKKKKK 244
Query: 316 TDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKT 375
D + ++ +Q + NP +T+ + A W SL Q +RKT
Sbjct: 245 KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGE-EQKQVYKRKT 303
Query: 376 -----VFSPTLPAARSSL---GSLQTPEAVTTRKGTGLLSS 408
+ L A R+SL + ++ EA T R L+S
Sbjct: 304 EAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLAS 344
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 30.4 bits (67), Expect = 5.8
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 25/161 (15%)
Query: 263 SASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARPPSG-------SSKA 315
S S A +S TPSP +S+ + D+ R + RA P SG K
Sbjct: 199 SPSPPASKSATPSPS-----SSINEEDADEANRAI----GEKRAAPDSGKKPKTPKKKKK 249
Query: 316 TDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKT 375
D + ++ +Q + NP +T+ + A W SL Q +RKT
Sbjct: 250 KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGE-EQKQVYKRKT 308
Query: 376 -----VFSPTLPAARSSL---GSLQTPEAVTTRKGTGLLSS 408
+ L A R+SL + ++ EA T R L+S
Sbjct: 309 EAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLAS 349
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 30.4 bits (67), Expect = 5.8
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 13/92 (14%)
Query: 304 DRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLT 363
DRAR A G + F NG+ G GS +L+SN + ++
Sbjct: 381 DRAREEIEMHIAMRTGNYIELNEENDFHYNGTDVSFEGGTLGSAWLSSNPVPPSRARMIS 440
Query: 364 SWTNDQ-------------GARRKTVFSPTLP 382
++ ND G+ R FSPT P
Sbjct: 441 NYRNDSSSSLGSGSTDSYFGSNRLADFSPTSP 472
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 30.4 bits (67), Expect = 5.8
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 14/88 (15%)
Query: 325 GTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAA 384
GT++R L Q+DL G P N + + S W D G R +P+ P+
Sbjct: 1097 GTNRRILV---QDDL--GLP-------NGLTFDAFSSQLCWV-DAGTNRAECLNPSQPSR 1143
Query: 385 RSSLGSLQTPEAVTTRKGTGLLSSDYRI 412
R +L LQ P AVT+ G L +D+++
Sbjct: 1144 RKALEGLQYPFAVTS-YGKNLYFTDWKM 1170
>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo
sapiens]
Length = 514
Score = 30.0 bits (66), Expect = 7.6
Identities = 39/154 (25%), Positives = 60/154 (38%), Gaps = 19/154 (12%)
Query: 308 PPSGSSKATDLGGTSQAGTSQRFLE--------NGSQEDLLHGNPGSTYLASNSTSAPNW 359
PPS S ATD G T+ ++ F E N S+E L+ +T + S T
Sbjct: 3 PPSSSVAATDTGQTTFTSSTATFPETITLTPNTNMSRESLMTPMTSTTPITSAITPTNTV 62
Query: 360 KSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTR-KGTGLLSSDYRIINGKSG 418
S+T+ T+ PT + S+L SL + +T T +++S + S
Sbjct: 63 TSMTTMTS----------PPTTTNSNSTLSSLTSSILSSTLVPSTDMITSHTTNLTRSSP 112
Query: 419 TQDIQPGPLFNNNADGVATDITSTRSLNYKSTSS 452
P + + T TS S ST+S
Sbjct: 113 LLATLPTTITRSTPTSETTYPTSPTSTVKGSTTS 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,593,632
Number of Sequences: 37866
Number of extensions: 1393435
Number of successful extensions: 3976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 3903
Number of HSP's gapped (non-prelim): 96
length of query: 699
length of database: 18,247,518
effective HSP length: 109
effective length of query: 590
effective length of database: 14,120,124
effective search space: 8330873160
effective search space used: 8330873160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.