Guide to the Human Genome
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Search of human proteins with 27477136

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27477136 zinc finger antiviral protein isoform 1 [Homo
sapiens]
         (902 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]   1857   0.0  
gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]   1440   0.0  
gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]              292   8e-79
gi|18087829 zinc finger CCCH-type, antiviral 1-like [Homo sapiens]    179   1e-44
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom...   148   2e-35
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap...   136   8e-32
gi|22749259 poly (ADP-ribose) polymerase family, member 15 isofo...   102   2e-21
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof...   102   2e-21
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom...    85   3e-16
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo...    69   2e-11
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo...    69   2e-11
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo...    69   2e-11
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo...    69   2e-11
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo...    69   2e-11
gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Hom...    64   8e-10
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    49   3e-05
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    46   1e-04
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo...    41   0.004
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo...    41   0.004
gi|60097902 filaggrin [Homo sapiens]                                   37   0.083
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    36   0.14 
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        36   0.18 
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    36   0.18 
gi|83367077 mucin 16 [Homo sapiens]                                    35   0.31 
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       35   0.41 
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    35   0.41 
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    35   0.41 
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             35   0.41 
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo...    33   0.92 
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP...    33   0.92 

>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
          Length = 902

 Score = 1857 bits (4811), Expect = 0.0
 Identities = 902/902 (100%), Positives = 902/902 (100%)

Query: 1   MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60
           MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
Sbjct: 1   MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60

Query: 61  TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120
           TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV
Sbjct: 61  TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120

Query: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180
           LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG
Sbjct: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180

Query: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240
           NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN
Sbjct: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240

Query: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300
           MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL
Sbjct: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300

Query: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360
           GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK
Sbjct: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360

Query: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420
           SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ
Sbjct: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420

Query: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480
           DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD
Sbjct: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480

Query: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540
           DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM
Sbjct: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540

Query: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600
           LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN
Sbjct: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600

Query: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660
           SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE
Sbjct: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660

Query: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDF 720
           LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDF
Sbjct: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDF 720

Query: 721 CFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKE 780
           CFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKE
Sbjct: 721 CFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKE 780

Query: 781 EGKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAKNVVM 840
           EGKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAKNVVM
Sbjct: 781 EGKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAKNVVM 840

Query: 841 FVAQVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTEDKACV 900
           FVAQVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTEDKACV
Sbjct: 841 FVAQVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTEDKACV 900

Query: 901 IS 902
           IS
Sbjct: 901 IS 902


>gi|27477138 zinc finger antiviral protein isoform 2 [Homo sapiens]
          Length = 699

 Score = 1440 bits (3728), Expect = 0.0
 Identities = 698/699 (99%), Positives = 699/699 (100%)

Query: 1   MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60
           MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
Sbjct: 1   MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI 60

Query: 61  TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120
           TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV
Sbjct: 61  TRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKV 120

Query: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180
           LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG
Sbjct: 121 LKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRG 180

Query: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240
           NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN
Sbjct: 181 NCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRN 240

Query: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300
           MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL
Sbjct: 241 MAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYL 300

Query: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360
           GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK
Sbjct: 301 GSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWK 360

Query: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420
           SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ
Sbjct: 361 SLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQ 420

Query: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480
           DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD
Sbjct: 421 DIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIAD 480

Query: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540
           DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM
Sbjct: 481 DADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQM 540

Query: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600
           LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN
Sbjct: 541 LIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPAN 600

Query: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660
           SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE
Sbjct: 601 SVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYE 660

Query: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPD 699
           LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGP+
Sbjct: 661 LSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPE 699


>gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]
          Length = 701

 Score =  292 bits (748), Expect = 8e-79
 Identities = 170/438 (38%), Positives = 239/438 (54%), Gaps = 50/438 (11%)

Query: 491 DSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFE 550
           DS   V+  T S+    + ++ICL H+ K C     C +VHFHLPYRWQ L    W D +
Sbjct: 257 DSSGSVSPNTLSQ---EEGDQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDRGKWEDLD 313

Query: 551 HMETIEKGYCNPGIH--LCSVG-----SYTINFRVMSCDSFPIRRLSTPSSVTKPANSVF 603
           +ME IE+ YCNP I   LCS       S+ +NF  M+  +   RRLST SSVTKP + + 
Sbjct: 314 NMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMTYGATQARRLSTASSVTKPPHFIL 373

Query: 604 TTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQS-CPRG------VVPFQAGS 656
           TT WIWYW +E G+W +YG +      + V SS +E  Y + C  G       + FQAG 
Sbjct: 374 TTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGK 433

Query: 657 RNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKR------GPDHQPAKTSSVSL 710
            NYEL F+  +Q N+   T K V RRP +V    V  M+       GP   P    S +L
Sbjct: 434 HNYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQTCNTKFPGPKSIPDYWDSSAL 493

Query: 711 TATFRPQEDFCFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDK 770
                P   F     +K  LS       EY +V   F  ++  + ++KI++++N  L + 
Sbjct: 494 -----PDPGF-----QKITLSSSSE---EYQKVWNLFNRTLPFYFVQKIERVQNLALWEV 540

Query: 771 FTWKKSQMKEEG-------KLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKD 823
           + W+K QM+++        + LF+ TS  +V++IC  NFD  +   H   YGKG YFA+D
Sbjct: 541 YQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARD 600

Query: 824 AIYSHKNCPYDAKNVVMFVAQVLVGKFTEGNITYTSPPPQ-------FDSCVDTRSNPSV 876
           A YSH     D +   MF+A+VLVG+F  GN ++  PP +       +DSCV++ S+PS+
Sbjct: 601 AAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNAFYDSCVNSVSDPSI 660

Query: 877 FVIFQKDQVYPQYVIEYT 894
           FVIF+K QVYP+YVI+YT
Sbjct: 661 FVIFEKHQVYPEYVIQYT 678



 Score =  136 bits (343), Expect = 8e-32
 Identities = 84/238 (35%), Positives = 128/238 (53%), Gaps = 14/238 (5%)

Query: 1   MADPEVCCFITKILCAHGGRMALDALLQEI--ALSEPQLCEVLQVAGPDRFVVLETGGEA 58
           MA   V   +T++LCA GG + L  L + +   LS   L  +L+  G  RFVV    G A
Sbjct: 1   MAQAGVVGEVTQVLCAAGGALELPELRRRLRMGLSADALERLLRQRG--RFVVAVRAGGA 58

Query: 59  GIT--RSVVATTRARVCRRKYCQRP-----CDNLHLCKLNLLGRCNYSQSERNLCKYSHE 111
                R V+A +  R+CR     +P     C  LHLC+  + G C + ++ +N C+ SH 
Sbjct: 59  AAAPERVVLAASPLRLCRAHQGSKPGCVGLCAQLHLCRFMVYGACKFLRAGKN-CRNSHS 117

Query: 112 VLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSY-KGEGRQQICNQQPPCSR 170
           + +E N  VL+ H +  L+  EL  LL Q+DP+ +PEIC+ Y KG+G    C  Q  C +
Sbjct: 118 LTTEHNLSVLRTHGVDHLSYNELCQLLFQNDPWLLPEICQHYNKGDGPHGSCAFQKQCIK 177

Query: 171 LHICDHFTRGNCRF-PNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKN 227
           LHIC +F +G C+F  +C RSH+  + + L  + + G++ D+V  +  I  + H  KN
Sbjct: 178 LHICQYFLQGECKFGTSCKRSHDFSNSENLEKLEKLGMSSDLVSRLPTIYRNAHDIKN 235


>gi|18087829 zinc finger CCCH-type, antiviral 1-like [Homo sapiens]
          Length = 300

 Score =  179 bits (454), Expect = 1e-44
 Identities = 98/247 (39%), Positives = 141/247 (57%), Gaps = 24/247 (9%)

Query: 1   MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLE------- 53
           MA+P VC F+TK+LCAHGGRM L  L   + LSE +L +VLQ AGP+RF++ E       
Sbjct: 1   MAEPTVCSFLTKVLCAHGGRMFLKDLRGHVELSEARLRDVLQRAGPERFLLQEVETQEGL 60

Query: 54  -----------TGGEAGITRSVVATTRARVC---RRKYCQRPCDNLHLCKLNLLGRCNYS 99
                       GG       VVA +  R+C   +R  CQ  CD LH C+ ++LG+C  +
Sbjct: 61  GDAEAEAAAGAVGGGGTSAWRVVAVSSVRLCARYQRGECQ-ACDQLHFCRRHMLGKCP-N 118

Query: 100 QSERNLCKYSHEVLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSY-KGEGR 158
           +   + C  SH++ +  N +VLK+H L GLN+ +L +LLLQ+DP  +PE+C  Y KGE  
Sbjct: 119 RDCWSTCTLSHDIHTPVNMQVLKSHGLFGLNENQLRILLLQNDPCLLPEVCLLYNKGEAL 178

Query: 159 QQICNQQPPCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDI 218
              CN +  C++ H+C  F +G C+   C RSH L+    L ++++ GLN   V N Q I
Sbjct: 179 YGYCNLKDKCNKFHVCKSFVKGECKLQTCKRSHQLIHAASLKLLQDQGLNIPSVVNFQII 238

Query: 219 CNSKHMQ 225
              KH++
Sbjct: 239 STYKHIK 245


>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
           sapiens]
          Length = 338

 Score =  148 bits (374), Expect = 2e-35
 Identities = 93/324 (28%), Positives = 163/324 (50%), Gaps = 53/324 (16%)

Query: 605 TKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQ 664
           T+W W++  E G W  +  + D     +V S  +E  +++ P G + F     +Y++ F 
Sbjct: 32  TQWGWFYLAECGKWHMF--QPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFA 89

Query: 665 GMIQTNIASKTQKDVIRRPTFVPQW-YVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFL 723
            M Q N+ +  Q+ + R P  +  + Y+ + +  P   P    +V+              
Sbjct: 90  EMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIP--MPPHWENVN-------------- 133

Query: 724 SSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEG- 782
           +   Y+L  +H+   EY  V+  F  +M   +I++I++I+N +L + F  KK+Q+K++  
Sbjct: 134 TQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRG 193

Query: 783 ------KLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAK 836
                 ++LF+ TS  +VE+IC +NFD  ++  H   +GKG YFA+DA YS + C  D K
Sbjct: 194 VPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIK 253

Query: 837 N--------------------VVMFVAQVLVGKFTEGNITYTSPPPQ-------FDSCVD 869
           +                      MF+A+VL+G +  G+  Y  PP +       +DSCVD
Sbjct: 254 HGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVD 313

Query: 870 TRSNPSVFVIFQKDQVYPQYVIEY 893
              NP +FV+F  +Q+YP+Y+I++
Sbjct: 314 DTWNPKIFVVFDANQIYPEYLIDF 337


>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
           sapiens]
          Length = 657

 Score =  136 bits (343), Expect = 8e-32
 Identities = 125/434 (28%), Positives = 187/434 (43%), Gaps = 73/434 (16%)

Query: 511 EICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKT--WTDF--EHMETIEKGYCNPGIHL 566
           EIC+D L   C     C K H  LPY WQ+    T  W     +  E +E+ YCNP    
Sbjct: 241 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR 300

Query: 567 CSVGSYTINF-------RVMSCDSFP-IRRLSTPSSVTKPANSVFTTKWIWYWKNESGTW 618
             +      F        V     F  +RRLSTP S     NS++ T W ++ ++  G W
Sbjct: 301 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSN--VNSIYHTVWKFFCRDHFG-W 357

Query: 619 IQYGEEKDKRKNSNVDSSYLESLYQSCPRGV--VPFQAGSRNYELSFQGMIQTNIASKTQ 676
            +Y E            S +  + ++  RG+  V F   + +Y L           S  +
Sbjct: 358 REYPE------------SVIRLIEEANSRGLKEVRFMMWNNHYILH---------NSFFR 396

Query: 677 KDVIRRPTFVPQW----YVQQMKRGPDHQPAKTSSVS----------LTATFRPQEDFCF 722
           +++ RRP F   +    Y+Q +   P   P    + S           +A F P+     
Sbjct: 397 REIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYM 456

Query: 723 LSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFK--IEKIKKIENSELLDKFTWKKSQMKE 780
             S+ +    +      Y  +   F  ++  FK  I +I +++N  L +K+  KK  M  
Sbjct: 457 HPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNR 516

Query: 781 E---------GKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNC 831
           +          + LF+ TS+  V+ IC +NFD  +   H   +G+G YFAK A YSH   
Sbjct: 517 KMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFS 576

Query: 832 PYDAKNV-VMFVAQVLVGKFTEGNITYTSPPP---------QFDSCVDTRSNPSVFVIFQ 881
              +K V  MF+A+VL G++T G+     PPP          +DSCVD    P +FVIF 
Sbjct: 577 KKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFN 636

Query: 882 KDQVYPQYVIEYTE 895
            DQ YP +VI+Y E
Sbjct: 637 DDQSYPYFVIQYEE 650


>gi|22749259 poly (ADP-ribose) polymerase family, member 15 isoform
           2 [Homo sapiens]
          Length = 444

 Score =  102 bits (254), Expect = 2e-21
 Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 18/238 (7%)

Query: 674 KTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFLSSKKYKLSEI 733
           KT K VI +P  +  +Y    KR         S+ S+T    P E +  ++ + + + ++
Sbjct: 207 KTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP-EHWTDMNHQLFCMVQL 265

Query: 734 HHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM------KEEGKLLFY 787
                EY  + + F  +  ++ IEKI++I+N+ L   +  KK QM      K   +LLF+
Sbjct: 266 EPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFH 325

Query: 788 ATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNC---PYDAKNVVMFVAQ 844
            T    V  +  + F+      +   YGKG YFA DA YS K+    P       M+V +
Sbjct: 326 GTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVR 385

Query: 845 VLVGKFTEGNITYTSPPPQ--------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYT 894
           VL G FT+G     +PPP+        FDS  +   +P +FV+F  +Q YP+Y+I +T
Sbjct: 386 VLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 443


>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
           1 [Homo sapiens]
          Length = 678

 Score =  102 bits (254), Expect = 2e-21
 Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 18/238 (7%)

Query: 674 KTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFLSSKKYKLSEI 733
           KT K VI +P  +  +Y    KR         S+ S+T    P E +  ++ + + + ++
Sbjct: 441 KTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP-EHWTDMNHQLFCMVQL 499

Query: 734 HHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM------KEEGKLLFY 787
                EY  + + F  +  ++ IEKI++I+N+ L   +  KK QM      K   +LLF+
Sbjct: 500 EPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFH 559

Query: 788 ATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNC---PYDAKNVVMFVAQ 844
            T    V  +  + F+      +   YGKG YFA DA YS K+    P       M+V +
Sbjct: 560 GTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVR 619

Query: 845 VLVGKFTEGNITYTSPPPQ--------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYT 894
           VL G FT+G     +PPP+        FDS  +   +P +FV+F  +Q YP+Y+I +T
Sbjct: 620 VLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677


>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
            sapiens]
          Length = 1801

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 60/194 (30%), Positives = 93/194 (47%), Gaps = 25/194 (12%)

Query: 717  QEDFCFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKS 776
            Q++FC +        E+    PEY  V+  F  +  +F+IEKI++I+N +L + +  KK 
Sbjct: 1614 QQNFCVV--------ELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKK 1665

Query: 777  QMKEEG------KLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKN 830
             M  +       K LF+ T    V  +  N F+      +   YGKG YFA +A YS  +
Sbjct: 1666 TMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSAND 1725

Query: 831  C---PYDAKNVVMFVAQVLVGKFTEGNITYTSPP---PQ-----FDSCVDTRSNPSVFVI 879
                P       ++  +VL G +T GN +   PP   PQ     +D+  D   +PS+FV 
Sbjct: 1726 TYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVA 1785

Query: 880  FQKDQVYPQYVIEY 893
            F   Q YP+Y+I +
Sbjct: 1786 FYDYQAYPEYLITF 1799


>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 24/162 (14%)

Query: 755 KIEKIKKIENSELLDKFTWKKSQMKEE------GKLLFYATSRAYVESICSNNFDSFLHE 808
           ++ K++KI+N  L+  F  KK  M+E+         LF      +   +C   F      
Sbjct: 632 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYST 691

Query: 809 THENKYGKGIYFAKDAIYSHKNCPYDAKNV-------VMFVAQVLVGKFTEGNITYTSPP 861
             + KYG GIYF K+     KN    AK +        +F A+VL G F +G+     PP
Sbjct: 692 PCDPKYGAGIYFTKNL----KNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPP 747

Query: 862 PQ-------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTED 896
           P         DS VD  S+P  FVIF   Q  PQY+   T++
Sbjct: 748 PLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQE 789


>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 24/162 (14%)

Query: 755 KIEKIKKIENSELLDKFTWKKSQMKEE------GKLLFYATSRAYVESICSNNFDSFLHE 808
           ++ K++KI+N  L+  F  KK  M+E+         LF      +   +C   F      
Sbjct: 632 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYST 691

Query: 809 THENKYGKGIYFAKDAIYSHKNCPYDAKNV-------VMFVAQVLVGKFTEGNITYTSPP 861
             + KYG GIYF K+     KN    AK +        +F A+VL G F +G+     PP
Sbjct: 692 PCDPKYGAGIYFTKNL----KNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPP 747

Query: 862 PQ-------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTED 896
           P         DS VD  S+P  FVIF   Q  PQY+   T++
Sbjct: 748 PLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQE 789


>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 24/162 (14%)

Query: 755 KIEKIKKIENSELLDKFTWKKSQMKEE------GKLLFYATSRAYVESICSNNFDSFLHE 808
           ++ K++KI+N  L+  F  KK  M+E+         LF      +   +C   F      
Sbjct: 632 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYST 691

Query: 809 THENKYGKGIYFAKDAIYSHKNCPYDAKNV-------VMFVAQVLVGKFTEGNITYTSPP 861
             + KYG GIYF K+     KN    AK +        +F A+VL G F +G+     PP
Sbjct: 692 PCDPKYGAGIYFTKNL----KNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPP 747

Query: 862 PQ-------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTED 896
           P         DS VD  S+P  FVIF   Q  PQY+   T++
Sbjct: 748 PLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQE 789


>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 24/162 (14%)

Query: 755 KIEKIKKIENSELLDKFTWKKSQMKEE------GKLLFYATSRAYVESICSNNFDSFLHE 808
           ++ K++KI+N  L+  F  KK  M+E+         LF      +   +C   F      
Sbjct: 667 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYST 726

Query: 809 THENKYGKGIYFAKDAIYSHKNCPYDAKNV-------VMFVAQVLVGKFTEGNITYTSPP 861
             + KYG GIYF K+     KN    AK +        +F A+VL G F +G+     PP
Sbjct: 727 PCDPKYGAGIYFTKNL----KNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPP 782

Query: 862 PQ-------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTED 896
           P         DS VD  S+P  FVIF   Q  PQY+   T++
Sbjct: 783 PLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQE 824


>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 24/162 (14%)

Query: 755 KIEKIKKIENSELLDKFTWKKSQMKEE------GKLLFYATSRAYVESICSNNFDSFLHE 808
           ++ K++KI+N  L+  F  KK  M+E+         LF      +   +C   F      
Sbjct: 667 QVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYST 726

Query: 809 THENKYGKGIYFAKDAIYSHKNCPYDAKNV-------VMFVAQVLVGKFTEGNITYTSPP 861
             + KYG GIYF K+     KN    AK +        +F A+VL G F +G+     PP
Sbjct: 727 PCDPKYGAGIYFTKNL----KNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPP 782

Query: 862 PQ-------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTED 896
           P         DS VD  S+P  FVIF   Q  PQY+   T++
Sbjct: 783 PLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQE 824


>gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Homo
            sapiens]
          Length = 1025

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 41/158 (25%), Positives = 79/158 (50%), Gaps = 14/158 (8%)

Query: 748  KASMKNFKIEKIKKI---ENSELLDKFTWKKSQMKEEGKLLFYATSRAYVESICSNNFDS 804
            ++S++  ++E++      +  EL  +   ++ + +   ++L++ T+   V  IC++ F+ 
Sbjct: 845  RSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNR 904

Query: 805  FLHETHENKYGKGIYFAKDA---IYSHKNCPYDAKNVVMFVAQVLVGKFTEGNITYTSPP 861
                 +   YGKG+YFA+ A   +    + P    +  +FVA+VL G + +G     +PP
Sbjct: 905  SFCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPP 964

Query: 862  --------PQFDSCVDTRSNPSVFVIFQKDQVYPQYVI 891
                     ++DS VD    PS+FVIF   Q  P ++I
Sbjct: 965  LRGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLI 1002


>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase 2 [Homo sapiens]
          Length = 1166

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 44/177 (24%), Positives = 78/177 (44%), Gaps = 34/177 (19%)

Query: 746  HFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEG------KLLFYATSRAYVESICS 799
            H       + I KI+K+ N +L +++T ++ ++ EE       ++LF+ +   +V +I  
Sbjct: 984  HAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSP--FVNAIIH 1041

Query: 800  NNFDSFLHETHENKYGKGIYFAKDAIYSHK---------NCP-------YDAKNVVMFVA 843
              FD   H      +G GIYFA+++  S++          CP       Y     ++F  
Sbjct: 1042 KGFDE-RHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCR 1100

Query: 844  QVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSV-------FVIFQKDQVYPQYVIEY 893
              L   F + +    +  P     V  R  PSV       +VI++ +Q YP+Y+I Y
Sbjct: 1101 VTLGKSFLQFSAMKMAHSPPGHHSVTGR--PSVNGLALAEYVIYRGEQAYPEYLITY 1155


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase [Homo sapiens]
          Length = 1327

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 40/170 (23%), Positives = 76/170 (44%), Gaps = 36/170 (21%)

Query: 754  FKIEKIKKIENSELLDKFTWKKSQMKEEG------KLLFYATSRAYVESICSNNFDSFLH 807
            + + +I+K+ N +L ++F  ++ ++ EE       ++LF+ +   ++ +I    FD   H
Sbjct: 1145 YNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSP--FINAIIHKGFDE-RH 1201

Query: 808  ETHENKYGKGIYFAKDAIYSHK---------NCP-------YDAKNVVMFVAQVLVGKFT 851
                  +G GIYFA+++  S++          CP       Y     ++F    L   F 
Sbjct: 1202 AYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFL 1261

Query: 852  E-GNITYTSPPPQFDSCVDTRSNPSV-------FVIFQKDQVYPQYVIEY 893
            +   +     PP   S +     PSV       +VI++ +Q YP+Y+I Y
Sbjct: 1262 QFSTMKMAHAPPGHHSVI---GRPSVNGLAYAEYVIYRGEQAYPEYLITY 1308


>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
           b [Homo sapiens]
          Length = 533

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 36/152 (23%)

Query: 738 PEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEG-----------KLLF 786
           PEY  +  + + +  N +   ++ I          WK +Q  EE            KLL+
Sbjct: 334 PEYKVIQTYLEQTGSNHRCPTLQHI----------WKVNQEGEEDRFQAHSKLGNRKLLW 383

Query: 787 YATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPY------DAKNV-V 839
           + T+ A V +I ++      H     + GKGIYFA +   + K+  Y       A +V  
Sbjct: 384 HGTNMAVVAAILTSGLRIMPHSG--GRVGKGIYFASE---NSKSAGYVIGMKCGAHHVGY 438

Query: 840 MFVAQVLVGK---FTEGNITYTSPPPQFDSCV 868
           MF+ +V +G+       N +  SPPP FDS +
Sbjct: 439 MFLGEVALGREHHINTDNPSLKSPPPGFDSVI 470


>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
           a [Homo sapiens]
          Length = 540

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 36/152 (23%)

Query: 738 PEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEG-----------KLLF 786
           PEY  +  + + +  N +   ++ I          WK +Q  EE            KLL+
Sbjct: 341 PEYKVIQTYLEQTGSNHRCPTLQHI----------WKVNQEGEEDRFQAHSKLGNRKLLW 390

Query: 787 YATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPY------DAKNV-V 839
           + T+ A V +I ++      H     + GKGIYFA +   + K+  Y       A +V  
Sbjct: 391 HGTNMAVVAAILTSGLRIMPHSG--GRVGKGIYFASE---NSKSAGYVIGMKCGAHHVGY 445

Query: 840 MFVAQVLVGK---FTEGNITYTSPPPQFDSCV 868
           MF+ +V +G+       N +  SPPP FDS +
Sbjct: 446 MFLGEVALGREHHINTDNPSLKSPPPGFDSVI 477


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 37.0 bits (84), Expect = 0.083
 Identities = 58/247 (23%), Positives = 84/247 (34%), Gaps = 18/247 (7%)

Query: 235  SSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLT 294
            SS  R+  +R  S S+    +G  E   + S SA       P Q SH+ S          
Sbjct: 2352 SSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA--GPHQQSHQESTRGRSAGRSG 2409

Query: 295  RK--FTYLGSQDRARPPSGSSKATDLGGTS-----QAGTSQRFLENGSQEDLLHGNPGST 347
            R   F Y  S       +     T  GG       QA  S R   +   +D +HG+PGS 
Sbjct: 2410 RSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS- 2468

Query: 348  YLASNSTSAPNWKSLTSWTNDQGARRK-TVFSPTLPAARSSLGSLQTPEAVTT--RKGTG 404
              +S      +++ L   +   G+    T       A+    GS           + G G
Sbjct: 2469 --SSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDG 2526

Query: 405  LLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQD 464
               S  R     S         +    ++G  T      S +  S S GH E S    + 
Sbjct: 2527 SRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSE---RW 2583

Query: 465  AGPASRD 471
            +G ASR+
Sbjct: 2584 SGSASRN 2590



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 54/248 (21%), Positives = 79/248 (31%), Gaps = 19/248 (7%)

Query: 230  GPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAP 289
            G R  SS  R+  +R  S S+    +G  E   + S SA     P        A  +   
Sbjct: 1374 GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGE 1433

Query: 290  VDDLTRKFTYLGSQDRARPPSGSSKATDLGGT-----SQAGTSQRFLENGSQEDLLHGNP 344
                +R F Y  S       +    A   GG       QA  S R   +   +D + G+P
Sbjct: 1434 SSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHP 1493

Query: 345  GSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRK--- 401
            G       S+      S    + D+        S T P  RS     Q+     +R+   
Sbjct: 1494 G-------SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRN 1546

Query: 402  ----GTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREI 457
                G G   S  R     +     +   +    + G  T      S++    S GH E 
Sbjct: 1547 EEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSED 1606

Query: 458  SSPRIQDA 465
            S  R + A
Sbjct: 1607 SERRSESA 1614


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 58/243 (23%), Positives = 89/243 (36%), Gaps = 51/243 (20%)

Query: 229 PGPRA---PSSHRRNMAYRARSKS-----RDRFFQGSQEFLASASASAERSCTPSPDQIS 280
           P P+A   P+   R +  R  S+S     RD   QGS +     S + +R+ T       
Sbjct: 523 PEPKAHYEPADRAREVPVRTTSRSPVLSRRDSPLQGSGQ---QNSQAGQRNST------- 572

Query: 281 HRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGT-------SQAGTSQRFLEN 333
             +S+E   + +   K          RP SGSS  +   G+       SQ+G+ +RF   
Sbjct: 573 --SSIEPRLLWERVEKLV-------PRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVR 623

Query: 334 GSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQT 393
            S +    G+P       N+   P  K             K VF P  PA    L +L  
Sbjct: 624 SSSKS--EGSPSQRL--ENAVKKPEDK-------------KEVFRPLKPAGEVDLTALAK 666

Query: 394 PEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSG 453
                         +DY   + +SGT D +   +    AD   +    TR+ +  + S+G
Sbjct: 667 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNG 726

Query: 454 HRE 456
             E
Sbjct: 727 ETE 729


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 60/284 (21%), Positives = 105/284 (36%), Gaps = 31/284 (10%)

Query: 231  PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
            PR+P++     +  +   S +     S+      +A  + + TP   + S  +       
Sbjct: 973  PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 1032

Query: 291  DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
            D   L    T  G    +     SS +TD   T+ +  S   L  G +    H NPGST+
Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTD---TALSPGSTTALSFGQESTTFHSNPGSTH 1089

Query: 349  --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
              L  +ST++      ++  +      +T  SP   T P  +    + QT  A T    +
Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 1149

Query: 404  GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
               ++   +   +S T    PG              T T      ST+SGH E      S
Sbjct: 1150 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 1194

Query: 459  SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
            SP      P+S     +GR  +    R++  +  ++ +  +T++
Sbjct: 1195 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 1237



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 65/302 (21%), Positives = 108/302 (35%), Gaps = 45/302 (14%)

Query: 228  PPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLED 287
            P  P  PS   ++  +    +S D     S     S+  S E S + S    +H  +  D
Sbjct: 2511 PGSPTTPSLSEKSTTFYTSPRSPDATL--SPATTTSSGVSEESSTSHSQPGSTHTTAFPD 2568

Query: 288  APVDD-----LTRKFTYLGSQDRARPP-----SGSSKATDLGGTSQAGT-------SQRF 330
            +          T   +  GS D    P     SG S+ +    +S   T       S   
Sbjct: 2569 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTA 2628

Query: 331  LENGSQEDLLHGNPGSTY--LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAAR 385
            L  G +    H +PGST+  L  +ST++      ++  +      +T  SP   T P  +
Sbjct: 2629 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQ 2688

Query: 386  SSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSL 445
                + QT  A T    +   ++   +   +S T    PG              T T   
Sbjct: 2689 GESTTFQTHPASTHTTPSPPSTATAPV--EESTTYHRSPGS-------------TPTTHF 2733

Query: 446  NYKSTSSGHRE-----ISSPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTT 500
               ST+SGH E      SSP      P+S     +GR  +    R++  +  ++ +  +T
Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGST 2792

Query: 501  SS 502
            ++
Sbjct: 2793 TT 2794



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 60/284 (21%), Positives = 106/284 (37%), Gaps = 31/284 (10%)

Query: 231  PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
            PR+P++     +  +   S +     S+      +A  + + TP   + S  +       
Sbjct: 3613 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 3672

Query: 291  DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
            D   L    T  GS   +     SS +TD   T+ +  S   L  G +    H +PGST+
Sbjct: 3673 DTTLLPASTTTSGSSQESTTSHSSSGSTD---TALSPGSTTALSFGQESTTFHSSPGSTH 3729

Query: 349  --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
              L  +ST++      ++  +      +T  SP   T P  +    + QT  A T    +
Sbjct: 3730 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 3789

Query: 404  GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
               ++   +   +S T    PG              T T      ST+SGH E      S
Sbjct: 3790 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 3834

Query: 459  SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
            SP      P+S     +GR  +    R++  +  ++ +  +T++
Sbjct: 3835 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 3877



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 58/284 (20%), Positives = 104/284 (36%), Gaps = 31/284 (10%)

Query: 231  PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
            PR+P++     +  +   S +     S+      +A  + + TP   + S  +       
Sbjct: 2056 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2115

Query: 291  DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
            D   L    T  G    +     S  +TD   T+ +  S   L  G +    H +PGST+
Sbjct: 2116 DTTLLPASTTTSGPSQESTTSHSSPGSTD---TALSPGSTTALSFGQESTTFHSSPGSTH 2172

Query: 349  --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
              L  +ST++      ++  +      +T  SP   T P  +    + QT  A T    +
Sbjct: 2173 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 2232

Query: 404  GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
               ++   +   +S T    PG              T T      ST+SGH E      S
Sbjct: 2233 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 2277

Query: 459  SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
            SP      P+S     +GR  +    R++  +  ++ +  +T++
Sbjct: 2278 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 2320


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 60/284 (21%), Positives = 105/284 (36%), Gaps = 31/284 (10%)

Query: 231 PRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV 290
           PR+P++     +  +   S +     S+      +A  + + TP   + S  +       
Sbjct: 460 PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 519

Query: 291 DD--LTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTY 348
           D   L    T  G    +     SS +TD   T+ +  S   L  G +    H NPGST+
Sbjct: 520 DTTLLPASTTTSGPSQESTTSHSSSGSTD---TALSPGSTTALSFGQESTTFHSNPGSTH 576

Query: 349 --LASNSTSAPNWKSLTSWTNDQGARRKTVFSP---TLPAARSSLGSLQTPEAVTTRKGT 403
             L  +ST++      ++  +      +T  SP   T P  +    + QT  A T    +
Sbjct: 577 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 636

Query: 404 GLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE-----IS 458
              ++   +   +S T    PG              T T      ST+SGH E      S
Sbjct: 637 PPSTATAPV--EESTTYHRSPGS-------------TPTTHFPASSTTSGHSEKSTIFHS 681

Query: 459 SPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSS 502
           SP      P+S     +GR  +    R++  +  ++ +  +T++
Sbjct: 682 SPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTT 724


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 61/251 (24%), Positives = 91/251 (36%), Gaps = 26/251 (10%)

Query: 230  GPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAP 289
            G +  S+ +  +    +S    +   G+ E   +  AS+ R+  P PD   H     D  
Sbjct: 6658 GLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPD---HSTESPDIS 6714

Query: 290  VDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYL 349
             + +      LG  + +     +     LG TSQ GT        S     H      + 
Sbjct: 6715 TEVIPSLPISLGITESSNMTIITRTGPPLGSTSQ-GTFTLDTPTTSSRAGTHSMATQEFP 6773

Query: 350  ASNSTSAPNWK-SLTSWTNDQGARRKTVFSPTL---PAARSSLGSLQTPEAVTTRKG--T 403
             S  T+  N    + SWT       KT FS +L   PA  S   S   P+ + T     T
Sbjct: 6774 HSEMTTVMNKDPEILSWTIPPSIE-KTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMT 6832

Query: 404  GLLSSDYRIINGKSGTQD----IQPGPLFNNNADGVATD-----------ITSTRSLNYK 448
             LL+    +     GT        P  L + + + + TD            TST + N +
Sbjct: 6833 SLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVE 6892

Query: 449  STSSGHREISS 459
            +TSSGH   SS
Sbjct: 6893 TTSSGHGSQSS 6903



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 71/344 (20%), Positives = 119/344 (34%), Gaps = 52/344 (15%)

Query: 206  GLNPDVVQN--IQDICNSKHMQKNPPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLAS 263
            G +PDV     I     +  +   P G +  +S       +  S S         E L +
Sbjct: 3441 GASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRA 3500

Query: 264  ASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQ 323
              ++ +    P+   +S  +S  +  + D+T             P  G S      GT+ 
Sbjct: 3501 NVSAVKSDIAPTAGHLSQTSSPAEVSILDVT-----------TAPTPGISTTITTMGTNS 3549

Query: 324  AGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLT---SWT-NDQGARRKTVFSP 379
              T+    E G     +   P +    +++     W S     SWT  D  +  K   SP
Sbjct: 3550 ISTTTPNPEVGMST--MDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSP 3607

Query: 380  ---------TLPAARSSLGSLQTPEAVTTRKGTGLL--SSDYRIINGKSGTQDIQPGPLF 428
                     +  A+ + L S+ TP    T  GT L+  SSD   +  ++ T +    P  
Sbjct: 3608 GTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSP-- 3665

Query: 429  NNNADGVATDITSTRSLNYKSTSSGHREIS---SPRIQDAGPASRDVQATGRIADDADPR 485
               +D  A+   ST S   + + S    +S   +P   +A      + +T   +   DP 
Sbjct: 3666 ---SDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPN 3722

Query: 486  VAL--------------VNDSLSDVTSTTSSRVDDHDSEEICLD 515
              L                 SLS  T+TTS+       +E+ L+
Sbjct: 3723 TPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLE 3766



 Score = 30.4 bits (67), Expect = 7.8
 Identities = 36/152 (23%), Positives = 56/152 (36%), Gaps = 21/152 (13%)

Query: 309   PSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPN-----WKSLT 363
             PS S   T    T   G  +    +GS        PG   L++ + S P+     + S T
Sbjct: 10280 PSLSEAMTSFATT---GVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSST 10336

Query: 364   SWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQ 423
               T D         S T+PA      S  TP  V T  GT   +++ R++   +     Q
Sbjct: 10337 FTTTD---------SSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQ 10387

Query: 424   PGPLFNNNADGVATDITSTRSLNYKSTSSGHR 455
             PG      +     D   T S+   + +S ++
Sbjct: 10388 PG----RTSSSPILDTRMTESVELGTVTSAYQ 10415


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 11/85 (12%)

Query: 604  TTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSF 663
            +  W W+  + SG W  Y        NS +DS++            V F AG R Y + F
Sbjct: 1614 SNNWRWF-DDRSGRWCSYSASN----NSTIDSAWKSG------ETSVRFTAGRRRYTVQF 1662

Query: 664  QGMIQTNIASKTQKDVIRRPTFVPQ 688
              M+Q N  +  ++ V+     VP+
Sbjct: 1663 TTMVQVNEETGNRRPVMLTLLRVPR 1687


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%)

Query: 307 RPPSGSSKATDLGGT-------SQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNW 359
           RP SGSS  +   G+       SQ+G+ +RF    S +    G+P       N+   P  
Sbjct: 644 RPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKS--EGSPSQRL--ENAVKKPED 699

Query: 360 KSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGT 419
           K             K VF P  PA    L +L                +DY   + +SGT
Sbjct: 700 K-------------KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGT 746

Query: 420 QDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE 456
            D +   +    AD   +    TR+ +  + S+G  E
Sbjct: 747 TDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETE 783


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%)

Query: 307 RPPSGSSKATDLGGT-------SQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNW 359
           RP SGSS  +   G+       SQ+G+ +RF    S +    G+P       N+   P  
Sbjct: 752 RPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKS--EGSPSQRL--ENAVKKPED 807

Query: 360 KSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGT 419
           K             K VF P  PA    L +L                +DY   + +SGT
Sbjct: 808 K-------------KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGT 854

Query: 420 QDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHRE 456
            D +   +    AD   +    TR+ +  + S+G  E
Sbjct: 855 TDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETE 891


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 34.7 bits (78), Expect = 0.41
 Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 21/139 (15%)

Query: 232 RAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVD 291
           R+ S  RR   +R+RS    R  +  ++         +R  T SP + SHR S   +   
Sbjct: 213 RSDSGSRRKRRHRSRSSKCKRKEKNKEK---------KRPHTESPGRRSHRHSSGSSHSP 263

Query: 292 DLTRKFTYLGSQDRARPP------------SGSSKATDLGGTSQAGTSQRFLENGSQEDL 339
            L+  ++   S  R  P             S  S++    G S  G+ QR   +G +   
Sbjct: 264 SLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGA 323

Query: 340 LHGNPGSTYLASNSTSAPN 358
             G PGS +   +  S+P+
Sbjct: 324 HGGRPGSAHSPPDKPSSPS 342


>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
           sapiens]
          Length = 1724

 Score = 33.5 bits (75), Expect = 0.92
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 13/105 (12%)

Query: 803 DSFLHETHENKYGKGIYFAKDAIYSHK-NCPYDAKNV-VMFVAQVLVGK---FTEGNITY 857
           D  +  T     G GIYF+     S K + P +     ++ +  V +GK     E + + 
Sbjct: 461 DRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSL 520

Query: 858 TSPPPQFDSCVDTRSNPSV--------FVIFQKDQVYPQYVIEYT 894
           T  PP +DS        SV        FV+++ +QV  +Y+I+++
Sbjct: 521 TEAPPGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFS 565


>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 1 [Homo sapiens]
          Length = 759

 Score = 33.5 bits (75), Expect = 0.92
 Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 252 RFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPV-DDLTRKFTYLGSQDRARPPS 310
           R  Q   + L S +++  +  T +  Q+   +   D      L R+ +  GS+  +   +
Sbjct: 459 RIMQKKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYET 518

Query: 311 GSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQG 370
           GS +   L      G + R  E+  +      + G + L ++S+S P++ S  SW+ D+ 
Sbjct: 519 GSGQKPYL----PMGEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDES 574

Query: 371 ARR 373
           ARR
Sbjct: 575 ARR 577


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,484,706
Number of Sequences: 37866
Number of extensions: 1747001
Number of successful extensions: 4977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 4868
Number of HSP's gapped (non-prelim): 83
length of query: 902
length of database: 18,247,518
effective HSP length: 111
effective length of query: 791
effective length of database: 14,044,392
effective search space: 11109114072
effective search space used: 11109114072
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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