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Search of human proteins with 27477041
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27477041 adaptor-related protein complex 2, alpha 2 subunit
[Homo sapiens]
(939 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27477041 adaptor-related protein complex 2, alpha 2 subunit [... 1847 0.0
gi|19913416 adaptor-related protein complex 2, alpha 1 subunit i... 1538 0.0
gi|19913414 adaptor-related protein complex 2, alpha 1 subunit i... 1529 0.0
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 277 4e-74
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 273 4e-73
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 253 6e-67
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit... 164 5e-40
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 149 2e-35
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 96 1e-19
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 96 1e-19
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 96 2e-19
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 96 2e-19
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 70 7e-12
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 44 7e-04
gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 41 0.006
gi|11415052 retinoid X receptor, beta [Homo sapiens] 38 0.039
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ... 37 0.066
gi|12707580 paired-like homeobox 2b [Homo sapiens] 37 0.066
gi|151301137 AT-hook transcription factor [Homo sapiens] 37 0.086
gi|163965366 nascent polypeptide-associated complex alpha subuni... 37 0.11
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 36 0.15
gi|158303333 synaptopodin isoform B [Homo sapiens] 36 0.15
gi|40353727 synaptopodin isoform A [Homo sapiens] 36 0.15
gi|157168329 formin 1 [Homo sapiens] 36 0.19
gi|122937321 UNC homeobox [Homo sapiens] 35 0.25
gi|171184447 myozenin 3 [Homo sapiens] 35 0.33
gi|171184445 myozenin 3 [Homo sapiens] 35 0.33
gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens] 35 0.33
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 35 0.33
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 35 0.43
>gi|27477041 adaptor-related protein complex 2, alpha 2 subunit
[Homo sapiens]
Length = 939
Score = 1847 bits (4784), Expect = 0.0
Identities = 939/939 (100%), Positives = 939/939 (100%)
Query: 1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
Sbjct: 1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
Query: 61 KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
Sbjct: 61 KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
Query: 121 ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP 180
ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP
Sbjct: 121 ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP 180
Query: 181 DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA 240
DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA
Sbjct: 181 DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA 240
Query: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQ 300
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQ
Sbjct: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQ 300
Query: 301 HSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF 360
HSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF
Sbjct: 301 HSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF 360
Query: 361 SHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIR 420
SHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIR
Sbjct: 361 SHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIR 420
Query: 421 EEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAK 480
EEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAK
Sbjct: 421 EEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAK 480
Query: 481 TVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALL 540
TVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALL
Sbjct: 481 TVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALL 540
Query: 541 LSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEE 600
LSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEE
Sbjct: 541 LSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEE 600
Query: 601 MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSAD 660
MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSAD
Sbjct: 601 MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSAD 660
Query: 661 LLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAPGSEDNFARFVCKNNGVLFEN 720
LLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAPGSEDNFARFVCKNNGVLFEN
Sbjct: 661 LLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAPGSEDNFARFVCKNNGVLFEN 720
Query: 721 QLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEG 780
QLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEG
Sbjct: 721 QLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEG 780
Query: 781 GAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQR 840
GAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQR
Sbjct: 781 GAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQR 840
Query: 841 WKQLSNPQQEVQNIFKAKHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQ 900
WKQLSNPQQEVQNIFKAKHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQ
Sbjct: 841 WKQLSNPQQEVQNIFKAKHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQ 900
Query: 901 IGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSAQF 939
IGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSAQF
Sbjct: 901 IGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSAQF 939
>gi|19913416 adaptor-related protein complex 2, alpha 1 subunit
isoform 2 [Homo sapiens]
Length = 955
Score = 1538 bits (3982), Expect = 0.0
Identities = 784/959 (81%), Positives = 852/959 (88%), Gaps = 24/959 (2%)
Query: 1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
Sbjct: 1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
Query: 61 KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
KLLFIFLLGHDIDFGHMEAVNLLSSN+YTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
Sbjct: 61 KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
Query: 121 ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP 180
ASRNPTFM LALHCIA+VGSREM EAFA +IP++LVAGD+MDSVKQSAALCLLRLY+ SP
Sbjct: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180
Query: 181 DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA 240
DLVPMG+WT+RVVHLLNDQH+GVVTAA SLIT L +KNP++FKT VSLAVSRLSRIV+SA
Sbjct: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240
Query: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPP-DPAVRGRLTECLETILNKAQEPPKSKKV 299
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPP D AV+GRL ECLET+LNKAQEPPKSKKV
Sbjct: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300
Query: 300 QHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 359
QHSNAKNA+LFE ISLIIH+DSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
Sbjct: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360
Query: 360 FSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSI 419
FSHEAVKTHI+TVINALKTERDVSVRQRA DLLYAMCDRSNA QIV+EML YLETADY+I
Sbjct: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420
Query: 420 REEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAA 479
REEIVLKVAILAEKYAVDY+WYVDTILNLIRIAGDYVSEEVWYRV+QIV NRDDVQGYAA
Sbjct: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480
Query: 480 KTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRAL 539
KTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP +QF LLHSKFHLCSV TRAL
Sbjct: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540
Query: 540 LLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLE 599
LLSTYIKF+NLFPE K TIQ VLR+ SQLRNADVELQQRAVEYL LS+VASTD+LATVLE
Sbjct: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600
Query: 600 EMPPFPERESSILAKLKKKKGPSTVTDLEDTKRD-RSVDVNGGPEPAPASTSAVSTPSPS 658
EMPPFPERESSILAKLK+KKGP + L+D +RD S D+NGG EP P S VSTPSPS
Sbjct: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTP---STVSTPSPS 657
Query: 659 ADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASV------------------VAPLAP 700
ADLLGL AAPP PA PP S+G LLVDVF A+ + P P
Sbjct: 658 ADLLGLRAAPP-PAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSPGPEDIGPPIP 716
Query: 701 GSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICS 760
+++ +FVCKNNGVLFENQLLQIG+KSEFRQNLGRM++FYGNKTS QF NF+PT++
Sbjct: 717 EADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHP 776
Query: 761 DDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLP 820
DLQ L +QTK V V+GGAQVQQV+NIEC+ DF P+L+++FRYGG Q ++++LP
Sbjct: 777 GDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGAPQALTLKLP 836
Query: 821 ITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKAKHPMDTEVTKAKIIGFGSALLEE 880
+T+NKFFQPTEMA+QDFFQRWKQLS PQQE Q IFKA HPMD EVTKAK++GFGSALL+
Sbjct: 837 VTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDN 896
Query: 881 VDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSAQF 939
VDPNP NFVGAGII TK Q+GCLLRLEPN QAQMYRLTLRTSKE VS+ LCELL+ QF
Sbjct: 897 VDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELLAQQF 955
>gi|19913414 adaptor-related protein complex 2, alpha 1 subunit
isoform 1 [Homo sapiens]
Length = 977
Score = 1530 bits (3960), Expect = 0.0
Identities = 784/981 (79%), Positives = 852/981 (86%), Gaps = 46/981 (4%)
Query: 1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
Sbjct: 1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC 60
Query: 61 KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
KLLFIFLLGHDIDFGHMEAVNLLSSN+YTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
Sbjct: 61 KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL 120
Query: 121 ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP 180
ASRNPTFM LALHCIA+VGSREM EAFA +IP++LVAGD+MDSVKQSAALCLLRLY+ SP
Sbjct: 121 ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP 180
Query: 181 DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA 240
DLVPMG+WT+RVVHLLNDQH+GVVTAA SLIT L +KNP++FKT VSLAVSRLSRIV+SA
Sbjct: 181 DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSA 240
Query: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPP-DPAVRGRLTECLETILNKAQEPPKSKKV 299
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPP D AV+GRL ECLET+LNKAQEPPKSKKV
Sbjct: 241 STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV 300
Query: 300 QHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 359
QHSNAKNA+LFE ISLIIH+DSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
Sbjct: 301 QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE 360
Query: 360 FSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSI 419
FSHEAVKTHI+TVINALKTERDVSVRQRA DLLYAMCDRSNA QIV+EML YLETADY+I
Sbjct: 361 FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI 420
Query: 420 REEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAA 479
REEIVLKVAILAEKYAVDY+WYVDTILNLIRIAGDYVSEEVWYRV+QIV NRDDVQGYAA
Sbjct: 421 REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA 480
Query: 480 KTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRAL 539
KTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP +QF LLHSKFHLCSV TRAL
Sbjct: 481 KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL 540
Query: 540 LLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLE 599
LLSTYIKF+NLFPE K TIQ VLR+ SQLRNADVELQQRAVEYL LS+VASTD+LATVLE
Sbjct: 541 LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE 600
Query: 600 EMPPFPERESSILAKLKKKKGPSTVTDLEDTKRD-RSVDVNGGPEPAPASTSAVSTPSPS 658
EMPPFPERESSILAKLK+KKGP + L+D +RD S D+NGG EP P S VSTPSPS
Sbjct: 601 EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTP---STVSTPSPS 657
Query: 659 ADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASV------------------------ 694
ADLLGL AAPP PA PP S+G LLVDVF A+
Sbjct: 658 ADLLGLRAAPP-PAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPM 716
Query: 695 ----------------VAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRM 738
+ P P +++ +FVCKNNGVLFENQLLQIG+KSEFRQNLGRM
Sbjct: 717 ALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRM 776
Query: 739 FIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTE 798
++FYGNKTS QF NF+PT++ DLQ L +QTK V V+GGAQVQQV+NIEC+ DF
Sbjct: 777 YLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLT 836
Query: 799 APVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKAK 858
P+L+++FRYGG Q ++++LP+T+NKFFQPTEMA+QDFFQRWKQLS PQQE Q IFKA
Sbjct: 837 PPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKAN 896
Query: 859 HPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRL 918
HPMD EVTKAK++GFGSALL+ VDPNP NFVGAGII TK Q+GCLLRLEPN QAQMYRL
Sbjct: 897 HPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRL 956
Query: 919 TLRTSKEAVSQRLCELLSAQF 939
TLRTSKE VS+ LCELL+ QF
Sbjct: 957 TLRTSKEPVSRHLCELLAQQF 977
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 277 bits (708), Expect = 4e-74
Identities = 214/715 (29%), Positives = 363/715 (50%), Gaps = 69/715 (9%)
Query: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
Query: 73 DFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLAL 132
FG +E + L++S ++T+K+IGYL +L++ ++ L+ N IKNDL GLAL
Sbjct: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
Query: 133 HCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRV 192
+ +GS EM AGE+ K+L ++ +++ AALC + + R P+L+ M +
Sbjct: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
Query: 193 VHLLNDQHLGVVTAATSLITTLAQKNPE---EFKTSVSLAVSRLSRIVTSASTDLQDYTY 249
+LLN+++ GV+ + L+T + +++P+ F+ V V L ++ S + D +
Sbjct: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSG 239
Query: 250 YFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVL 309
+ P+L V++LRLL+ D +E + IL + ++ K N NA+L
Sbjct: 240 --ISDPFLQVRILRLLRILGRNDDDS----SEAMNDILAQVATNTETSK----NVGNAIL 289
Query: 310 FEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHI 369
+E + I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV+ H
Sbjct: 290 YETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQRHR 347
Query: 370 ETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAI 429
T+++ LK + DVS+++RA++L +A+ + +N ++ E+L +L++ + + + + +
Sbjct: 348 STIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFL 406
Query: 430 LAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAP 489
AEKYA W++DTI+ ++ AG YV ++ +IQ++ N ++ Y + +++A+
Sbjct: 407 AAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGD 466
Query: 490 ACHENLVKVGGYILGEFGN-LIAGDPRSSPLIQ------FHLLHSKF--HLCSVPTRALL 540
+ LV+V + +GE+G+ L++G IQ +L S ++ + TR
Sbjct: 467 YSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYA 526
Query: 541 LSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEE 600
L+ +K F I+ V+ + DVELQQRAVEY L D + + L E
Sbjct: 527 LTAIMKLSTRFTCTVNRIKKVVSIYGS--SIDVELQQRAVEYNAL--FKKYDHMRSALLE 582
Query: 601 MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTS-AVSTPSPSA 659
P E+ ++ GP+ + V NG EPAP T S P P++
Sbjct: 583 RMPVMEKVTT--------NGPTEI-----------VQTNGETEPAPLETKPPPSGPQPTS 623
Query: 660 ------DLLG----LGAAPPAPAGPPPSSGGS--GLLVDVFSDSASVVAPLAPGS 702
DLLG P AP P S+GG LL D+ A AP AP S
Sbjct: 624 QANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAP-APAS 677
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 273 bits (699), Expect = 4e-73
Identities = 214/718 (29%), Positives = 364/718 (50%), Gaps = 72/718 (10%)
Query: 13 LAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDI 72
L I IR +++ E + I KE A IRS F+ + D + + V KLL++ +LG+
Sbjct: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPA 63
Query: 73 DFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLAL 132
FG +E + L++S ++T+K+IGYL +L++ ++ L+ N IKNDL GLAL
Sbjct: 64 HFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLAL 123
Query: 133 HCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRV 192
+ +GS EM AGE+ K+L ++ +++ AALC + + R P+L+ M +
Sbjct: 124 CTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPAT 179
Query: 193 VHLLNDQHLGVVTAATSLITTLAQKNPE---EFKTSVSLA---VSRLSRIVTSASTDLQD 246
+LLN+++ GV+ + L+T + +++P+ F+ + L V L ++ S + D
Sbjct: 180 KNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHD 239
Query: 247 YTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKN 306
+ + P+L V++LRLL+ D +E + IL + ++ K N N
Sbjct: 240 VSG--ISDPFLQVRILRLLRILGRNDDDS----SEAMNDILAQVATNTETSK----NVGN 289
Query: 307 AVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVK 366
A+L+E + I+ SE L V A N LG+FL + + N+RY+AL S+ L + + H AV+
Sbjct: 290 AILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSL--LKTVQTDHNAVQ 347
Query: 367 THIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLK 426
H T+++ LK + DVS+++RA++L +A+ + +N ++ E+L +L++ + + +
Sbjct: 348 RHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASG 406
Query: 427 VAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEAL 486
+ + AEKYA W++DTI+ ++ AG YV ++ +IQ++ N ++ Y + +++A+
Sbjct: 407 IFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAI 466
Query: 487 QAPACHENLVKVGGYILGEFGN-LIAGDPRSSPLIQ------FHLLHSKF--HLCSVPTR 537
+ LV+V + +GE+G+ L++G IQ +L S ++ + TR
Sbjct: 467 LGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTR 526
Query: 538 ALLLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATV 597
L+ +K F I+ V+ + DVELQQRAVEY L D + +
Sbjct: 527 GYALTAIMKLSTRFTCTVNRIKKVVSIYGS--SIDVELQQRAVEYNAL--FKKYDHMRSA 582
Query: 598 LEEMPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTS-AVSTPS 656
L E P E+ ++ GP+ + V NG EPAP T S P
Sbjct: 583 LLERMPVMEKVTT--------NGPTEI-----------VQTNGETEPAPLETKPPPSGPQ 623
Query: 657 PSA------DLLG----LGAAPPAPAGPPPSSGGS--GLLVDVFSDSASVVAPLAPGS 702
P++ DLLG P AP P S+GG LL D+ A AP AP S
Sbjct: 624 PTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAP-APAS 680
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 253 bits (646), Expect = 6e-67
Identities = 203/686 (29%), Positives = 339/686 (49%), Gaps = 56/686 (8%)
Query: 17 ISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGH 76
I +IR K++ E + I KE A+IR+ F+ D + + + KLL++ +LG+ FG
Sbjct: 12 IEEIRGAKTQAQEREVIQKECAHIRASFRDG---DPVHRHRQLAKLLYVHMLGYPAHFGQ 68
Query: 77 MEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIA 136
ME + L++S+R+T+K++GYL +L++ + LI N+IKNDL+ GLAL ++
Sbjct: 69 MECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLS 128
Query: 137 SVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLL 196
++GS EM A E+ K+L+ V++ A L + + R P+L + + LL
Sbjct: 129 TMGSAEMCRDLAPEVEKLLL--QPSPYVRKKAILTAVHMIRKVPELSSV--FLPPCAQLL 184
Query: 197 NDQHLGVVTAATSLITTLAQKNP---EEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVP 253
+++H G++ +LIT L +++P F+ V V L +VT + +++ V
Sbjct: 185 HERHHGILLGTITLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYS--TEHSISGVS 242
Query: 254 APWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAI 313
P+L V++LRLL+ + GR E +N + NA NAVLFE +
Sbjct: 243 DPFLQVQILRLLR--------ILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETV 294
Query: 314 SLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVI 373
I+ S L V A N LG+FL + + N+RY+AL S+ L S+ H AV+ H TV+
Sbjct: 295 LTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSD--HSAVQRHRPTVV 352
Query: 374 NALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEK 433
L+ E D S+ +RA++L A+ + SN ++ E+ ++LE+ +R + + + AE+
Sbjct: 353 ECLR-ETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAER 411
Query: 434 YAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHE 493
+A W++DTIL+++ AG +V ++ + Q++ ++ Y+ + ++ AL +
Sbjct: 412 FAPTKRWHIDTILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQQ 471
Query: 494 NLVKVGGYILGEFGN-LIAGDPRSSPLIQ------FHLLHS--KFHLCSVPTRALLLSTY 544
LV+V + +GE+G+ L+AG+ +Q LL + H+ TR L+
Sbjct: 472 PLVQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTAL 531
Query: 545 IKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMP-- 602
+K I+ V+ DVELQQRAVEY L + A +LE+MP
Sbjct: 532 MKLSTRLCGDNNRIRQVVSIYGSC--LDVELQQRAVEYDTLFR-KYDHMRAAILEKMPLV 588
Query: 603 ----PFPERES---------SILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPAST 649
P + E+ S A + + S + DL D S DV P P+
Sbjct: 589 ERDGPQADEEAKESKEAAQLSEAAPVPTEPQASQLLDLLDLLDGASGDVQHPPHLDPSPG 648
Query: 650 SAVSTPSPSADLLGLGAAPPAPAGPP 675
A+ LL L PP PA P
Sbjct: 649 GAL------VHLLDLPCVPPPPAPIP 668
>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
[Homo sapiens]
Length = 1137
Score = 164 bits (414), Expect = 5e-40
Identities = 136/566 (24%), Positives = 262/566 (46%), Gaps = 45/566 (7%)
Query: 2 PAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCK 61
PA +K L + I SK E K I +EL+++++ K+ V +
Sbjct: 25 PAAAKASFSSRLGSLVRGITALTSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMV-R 83
Query: 62 LLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLA 121
L++ +LG+D FG++ A+ L EK++GYL +S+ ++ + EL+ L+ N + DL
Sbjct: 84 LIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQ 143
Query: 122 SRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPD 181
S N + +AL ++ + EM A I L + + V++ A L L + + +P+
Sbjct: 144 STNLVEVCMALTVVSQIFPCEMIPAVLPLIEDKL--QHSKEIVRRKAVLALYKFHLIAPN 201
Query: 182 LVPMGDWTSRVVHL-----LNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRI 236
V + +H+ L D+ +GV+ A+ + + ++N +K V+ L ++
Sbjct: 202 QV-------QHIHIKFRKALCDRDVGVMAASLHIYLRMIKENSSGYKDLTGSFVTILKQV 254
Query: 237 VTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKS 296
V ++ Y+ VPAPWL ++LLR+L D + + L+ L +A+
Sbjct: 255 VGGKLP--VEFNYHSVPAPWLQIQLLRILGLLGKDDQRTSELMYDVLDESLRRAE----- 307
Query: 297 KKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLA 356
+ N A+LFE + + + LL +A +G+F+ + NL+YL L+++ +
Sbjct: 308 ---LNHNVTYAILFECVHTVYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVI 364
Query: 357 SSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYL-ETA 415
+ H T+I L D +++ ++LLY + + N IV +ML YL ++
Sbjct: 365 QQD--PTLALQHQMTIIECL-DHPDPIIKRETLELLYRITNAQNITVIVQKMLEYLHQSK 421
Query: 416 DYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDD-- 473
+ + +V K+A LAEKYA D W++ T+ + + GD + ++ ++++ D
Sbjct: 422 EEYVIVNLVGKIAELAEKYAPDNAWFIQTMNAVFSVGGDVMHPDIPNNFLRLLAEGFDDE 481
Query: 474 ----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFH 523
VQ Y E + P + ++V ++LGE+ L+ + + + +
Sbjct: 482 TEDQQLRLYAVQSYLTLLDMENVFYP---QRFLQVMSWVLGEYSYLLDKETPEEVIAKLY 538
Query: 524 LLHSKFHLCSVPTRALLLSTYIKFVN 549
L + S T+A L++ K +
Sbjct: 539 KLLMNDSVSS-ETKAWLIAAVTKLTS 563
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 149 bits (375), Expect = 2e-35
Identities = 114/483 (23%), Positives = 242/483 (50%), Gaps = 38/483 (7%)
Query: 11 RGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGH 70
+ L + IRN KE E K I++ + I+ + K D K VCKL ++ +LG+
Sbjct: 16 KNLQDLVRGIRN--HKEDEAKYISQCIDEIKQELKQDNIA---VKANAVCKLTYLQMLGY 70
Query: 71 DIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGL 130
DI + + ++S++++T K+IGYL S + +++I L N I+ DL+S + G+
Sbjct: 71 DISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGV 130
Query: 131 ALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTS 190
AL ++ + ++A A +I + + T +++ A L + +++ P+ +
Sbjct: 131 ALTGLSCFVTPDLARDLANDI--MTLMSHTKPYIRKKAVLIMYKVFLKYPE--SLRPAFP 186
Query: 191 RVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYY 250
R+ L D GV +AA ++I LA++NP+ + + L +++TS++ +
Sbjct: 187 RLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPL----FFKLMTSSTNN------- 235
Query: 251 FVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLF 310
W+ +K+++L P +P + +L E L +++ S + N AVL
Sbjct: 236 -----WVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTS--AMSLLYECVNTVIAVLI 288
Query: 311 EAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIE 370
S + +H + L V+ +L ++ + NL+YL L +M + + ++V++H +
Sbjct: 289 SLSSGMPNHSASIQLCVQ---KLRILIEDSDQNLKYLGLLAMSKILKTH--PKSVQSHKD 343
Query: 371 TVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETAD-YSIREEIVLKVAI 429
++ L ++D S+R RA+DLLY M + N +IV +++++++ A+ + R+E++ K+
Sbjct: 344 LILQCL-DDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIID 402
Query: 430 LAE----KYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEA 485
+ +Y ++ WY+ ++ L R+ G + +++ + I ++ +A +
Sbjct: 403 ICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSAL 462
Query: 486 LQA 488
L +
Sbjct: 463 LDS 465
>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
isoform a [Homo sapiens]
Length = 949
Score = 96.3 bits (238), Expect = 1e-19
Identities = 148/684 (21%), Positives = 275/684 (40%), Gaps = 96/684 (14%)
Query: 36 ELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGY 95
E+ ++++ DK KK+ V K++ +G D+ + VN + ++ K++ Y
Sbjct: 14 EIFELKAELNSDKK---EKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVY 70
Query: 96 LFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVL 155
L++ S ++ + N D NP LA+ + + ++ E + K L
Sbjct: 71 LYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCL 130
Query: 156 VAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLA 215
D V+++AA+C+ +L+ + LV + + L++D + VV A + ++ +A
Sbjct: 131 KDEDPY--VRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIA 188
Query: 216 QKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAV 275
+ +P + L +++++T+ L + T W + +L L Y P D
Sbjct: 189 ESHPS--SNLLDLNPQSINKLLTA----LNECT------EWGQIFILDCLANYMPKDD-- 234
Query: 276 RGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHH--------DSEPNLLV 327
+AQ + + S+A +AV+ A+ +++ D LL
Sbjct: 235 ------------REAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLK 282
Query: 328 RACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQR 387
+ L L E L+Y+AL ++ + E +K ++ +K + V+
Sbjct: 283 KLAPPLVTLLS-AEPELQYVALRNINLIVQKR--PEILKHEMKVFF--VKYNDPIYVKLE 337
Query: 388 AVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILN 447
+D++ + ++N Q++AE+ Y D + V + A K V T+L+
Sbjct: 338 KLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLD 397
Query: 448 LIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGG------- 500
LI+ +YV +E IV+ +D + Y K +E++ A C ENL +
Sbjct: 398 LIQTKVNYVVQEA------IVVIKDIFRKYPNK--YESVIATLC-ENLDSLDEPEARAAM 448
Query: 501 -YILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIK-FVNLFPEVKPTI 558
+I+GE+ I + L++ L FH S + LL+ +K F+ E + +
Sbjct: 449 IWIVGEYAERI---DNADELLESFL--EGFHDESTQVQLQLLTAIVKLFLKKPTETQELV 503
Query: 559 QDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPER----ESSILAK 614
Q VL +Q + + +L+ R Y RL + VL E P E E ++L +
Sbjct: 504 QQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDE 562
Query: 615 L---------KKKKGPSTVTD-----LEDTKRDRSVDVNGGPEPAPASTSAVSTPSPS-- 658
L K PS + + + R+ P A T A P
Sbjct: 563 LICYIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPDVI 622
Query: 659 -------ADLLGLGAAPPAPAGPP 675
DLL L PP +GPP
Sbjct: 623 PAQGDLLGDLLNLDLGPPV-SGPP 645
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 96.3 bits (238), Expect = 1e-19
Identities = 148/684 (21%), Positives = 275/684 (40%), Gaps = 96/684 (14%)
Query: 36 ELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGY 95
E+ ++++ DK KK+ V K++ +G D+ + VN + ++ K++ Y
Sbjct: 14 EIFELKAELNSDKK---EKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVY 70
Query: 96 LFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVL 155
L++ S ++ + N D NP LA+ + + ++ E + K L
Sbjct: 71 LYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCL 130
Query: 156 VAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLA 215
D V+++AA+C+ +L+ + LV + + L++D + VV A + ++ +A
Sbjct: 131 KDEDPY--VRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIA 188
Query: 216 QKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAV 275
+ +P + L +++++T+ L + T W + +L L Y P D
Sbjct: 189 ESHPS--SNLLDLNPQSINKLLTA----LNECT------EWGQIFILDCLANYMPKDD-- 234
Query: 276 RGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHH--------DSEPNLLV 327
+AQ + + S+A +AV+ A+ +++ D LL
Sbjct: 235 ------------REAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLK 282
Query: 328 RACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQR 387
+ L L E L+Y+AL ++ + E +K ++ +K + V+
Sbjct: 283 KLAPPLVTLLS-AEPELQYVALRNINLIVQKR--PEILKHEMKVFF--VKYNDPIYVKLE 337
Query: 388 AVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILN 447
+D++ + ++N Q++AE+ Y D + V + A K V T+L+
Sbjct: 338 KLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLD 397
Query: 448 LIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGG------- 500
LI+ +YV +E IV+ +D + Y K +E++ A C ENL +
Sbjct: 398 LIQTKVNYVVQEA------IVVIKDIFRKYPNK--YESVIATLC-ENLDSLDEPEARAAM 448
Query: 501 -YILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIK-FVNLFPEVKPTI 558
+I+GE+ I + L++ L FH S + LL+ +K F+ E + +
Sbjct: 449 IWIVGEYAERI---DNADELLESFL--EGFHDESTQVQLQLLTAIVKLFLKKPTETQELV 503
Query: 559 QDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPER----ESSILAK 614
Q VL +Q + + +L+ R Y RL + VL E P E E ++L +
Sbjct: 504 QQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDE 562
Query: 615 L---------KKKKGPSTVTD-----LEDTKRDRSVDVNGGPEPAPASTSAVSTPSPS-- 658
L K PS + + + R+ P A T A P
Sbjct: 563 LICYIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPDVI 622
Query: 659 -------ADLLGLGAAPPAPAGPP 675
DLL L PP +GPP
Sbjct: 623 PAQGDLLGDLLNLDLGPPV-SGPP 645
>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
isoform a [Homo sapiens]
Length = 951
Score = 95.9 bits (237), Expect = 2e-19
Identities = 127/596 (21%), Positives = 247/596 (41%), Gaps = 59/596 (9%)
Query: 25 SKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLS 84
+K+ EI + EL N + + +K+ V K++ +G D+ + VN +
Sbjct: 10 NKKGEIFELKAELNNEKKE----------KRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQ 59
Query: 85 SNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMA 144
++ K++ YL++ S ++ + N+ D NP LA+ + + ++
Sbjct: 60 TDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKIT 119
Query: 145 EAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVV 204
E + K L D V+++AA+C+ +L+ + +V + + L+ D + VV
Sbjct: 120 EYLCEPLRKCLKDEDPY--VRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVV 177
Query: 205 TAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRL 264
A + ++ +++ +P + L +++++T+ L + T W + +L
Sbjct: 178 ANAVAALSEISESHPN--SNLLDLNPQNINKLLTA----LNECT------EWGQIFILDC 225
Query: 265 LQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPN 324
L Y P D + E + L+ A V+ VL + + L+ N
Sbjct: 226 LSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVK-------VLMKFLELLPKDSDYYN 278
Query: 325 LLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSV 384
+L++ L E ++Y+AL ++ + E +K I+ +K + V
Sbjct: 279 MLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR--PEILKQEIKVFF--VKYNDPIYV 334
Query: 385 RQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDT 444
+ +D++ + ++N Q++AE+ Y D + V + A K V T
Sbjct: 335 KLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVST 394
Query: 445 ILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGG---- 500
+L+LI+ +YV +E IV+ RD + Y K +E++ A C ENL +
Sbjct: 395 LLDLIQTKVNYVVQEA------IVVIRDIFRKYPNK--YESIIATLC-ENLDSLDEPDAR 445
Query: 501 ----YILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIK-FVNLFPEVK 555
+I+GE+ I + L++ L FH S + LL+ +K F+ E +
Sbjct: 446 AAMIWIVGEYAERI---DNADELLESFL--EGFHDESTQVQLTLLTAIVKLFLKKPSETQ 500
Query: 556 PTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSI 611
+Q VL +Q + + +L+ R Y RL + VL E P E I
Sbjct: 501 ELVQQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLI 555
>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
isoform b [Homo sapiens]
Length = 937
Score = 95.9 bits (237), Expect = 2e-19
Identities = 127/596 (21%), Positives = 247/596 (41%), Gaps = 59/596 (9%)
Query: 25 SKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLS 84
+K+ EI + EL N + + +K+ V K++ +G D+ + VN +
Sbjct: 10 NKKGEIFELKAELNNEKKE----------KRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQ 59
Query: 85 SNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMA 144
++ K++ YL++ S ++ + N+ D NP LA+ + + ++
Sbjct: 60 TDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKIT 119
Query: 145 EAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVV 204
E + K L D V+++AA+C+ +L+ + +V + + L+ D + VV
Sbjct: 120 EYLCEPLRKCLKDEDPY--VRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVV 177
Query: 205 TAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRL 264
A + ++ +++ +P + L +++++T+ L + T W + +L
Sbjct: 178 ANAVAALSEISESHPN--SNLLDLNPQNINKLLTA----LNECT------EWGQIFILDC 225
Query: 265 LQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPN 324
L Y P D + E + L+ A V+ VL + + L+ N
Sbjct: 226 LSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVK-------VLMKFLELLPKDSDYYN 278
Query: 325 LLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSV 384
+L++ L E ++Y+AL ++ + E +K I+ +K + V
Sbjct: 279 MLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR--PEILKQEIKVFF--VKYNDPIYV 334
Query: 385 RQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDT 444
+ +D++ + ++N Q++AE+ Y D + V + A K V T
Sbjct: 335 KLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVST 394
Query: 445 ILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGG---- 500
+L+LI+ +YV +E IV+ RD + Y K +E++ A C ENL +
Sbjct: 395 LLDLIQTKVNYVVQEA------IVVIRDIFRKYPNK--YESIIATLC-ENLDSLDEPDAR 445
Query: 501 ----YILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIK-FVNLFPEVK 555
+I+GE+ I + L++ L FH S + LL+ +K F+ E +
Sbjct: 446 AAMIWIVGEYAERI---DNADELLESFL--EGFHDESTQVQLTLLTAIVKLFLKKPSETQ 500
Query: 556 PTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSI 611
+Q VL +Q + + +L+ R Y RL + VL E P E I
Sbjct: 501 ELVQQVLSLATQ-DSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLI 555
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 70.5 bits (171), Expect = 7e-12
Identities = 52/246 (21%), Positives = 120/246 (48%), Gaps = 28/246 (11%)
Query: 265 LQCYPPPDPA------VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLII- 317
L C+ PD A + ++ I KA+ + HS + ++L+E ++ +I
Sbjct: 135 LSCFVTPDLARDLANDIMTLMSHTKPYIRKKAKLIEPLTNLIHSTSAMSLLYECVNTVIA 194
Query: 318 ----------HHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKT 367
+H + L V+ +L ++ + NL+YL L +M + + ++V++
Sbjct: 195 VLISLSSGMPNHSASIQLCVQ---KLRILIEDSDQNLKYLGLLAMSKILKTH--PKSVQS 249
Query: 368 HIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETAD-YSIREEIVLK 426
H + ++ L ++D S+R RA+DLLY M + N +IV +++++++ A+ + R+E++ K
Sbjct: 250 HKDLILQCLD-DKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTK 308
Query: 427 VAILAE----KYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTV 482
+ + +Y ++ WY+ ++ L R+ G + +++ + I ++ +A +
Sbjct: 309 IIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQM 368
Query: 483 FEALQA 488
L +
Sbjct: 369 SALLDS 374
Score = 69.3 bits (168), Expect = 2e-11
Identities = 65/287 (22%), Positives = 132/287 (45%), Gaps = 31/287 (10%)
Query: 11 RGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGH 70
+ L + IRN KE E K I++ + I+ + K D K VCKL ++ +LG+
Sbjct: 16 KNLQDLVRGIRN--HKEDEAKYISQCIDEIKQELKQDNIA---VKANAVCKLTYLQMLGY 70
Query: 71 DIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGL 130
DI + + ++S++++T K+IGYL S + +++I L N I+ DL+S + G+
Sbjct: 71 DISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGV 130
Query: 131 ALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALC--LLRLYRTSPDLVPMGDW 188
AL ++ + ++A A +I + + T +++ A L L L ++ + + +
Sbjct: 131 ALTGLSCFVTPDLARDLANDI--MTLMSHTKPYIRKKAKLIEPLTNLIHSTSAMSLLYEC 188
Query: 189 TSRVVHLLNDQHLGVVTAATSL------ITTLAQKNPEEFKTSVSLAVSRLSRIVTSAST 242
+ V+ +L G+ + S+ + L + + + K LA+S++ + +
Sbjct: 189 VNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQ 248
Query: 243 DLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNK 289
+D +LQC D ++R R + L +++K
Sbjct: 249 SHKDL----------------ILQCLDDKDESIRLRALDLLYGMVSK 279
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 43.9 bits (102), Expect = 7e-04
Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 590 STDILATVLE----EMPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSV------DVN 639
S D+L V E + P P S+L +L+ + TV+ ++ R +
Sbjct: 122 SEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGD 181
Query: 640 GGPEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPS 677
GGP P PA +SA S+PSPS PP P PP+
Sbjct: 182 GGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPA 219
Score = 30.4 bits (67), Expect = 8.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 7/40 (17%)
Query: 641 GPEPAPASTSAVSTPSPSADLL-------GLGAAPPAPAG 673
G PAP TS P PS+ LL G G+ PP P G
Sbjct: 1145 GMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTG 1184
>gi|166197671 adaptor-related protein complex 4, beta 1 subunit
[Homo sapiens]
Length = 739
Score = 40.8 bits (94), Expect = 0.006
Identities = 100/497 (20%), Positives = 180/497 (36%), Gaps = 58/497 (11%)
Query: 27 EAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN 86
E +K + K L N + D + + +++ G D+ ME V ++
Sbjct: 7 EDVVKELKKALCNPHIQ------ADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV 60
Query: 87 RYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEA 146
+K++ YL++ +L L N + D + NP GLAL + S+ + E
Sbjct: 61 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY 120
Query: 147 FAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQH-LGVVT 205
I L D V++ A L +++ D G + + LL DQ + VV
Sbjct: 121 IQQPILNGL--RDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVN 178
Query: 206 AATSLITTLAQKNPEEFKTSVS-LAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRL 264
SL L Q+ ++ ++R+S++ W ++L
Sbjct: 179 CLRSLEEILKQEGGVVINKPIAHHLLNRMSKL-----------------DQWGQAEVLNF 221
Query: 265 LQCYPPPDPAVRGRLTECLETILNKAQEPPKSKK--VQHSNAKNAVLFEAISLIIHHDSE 322
L Y P R E L ILN KS V K LF ++ + H +
Sbjct: 222 LLRYQP-------RSEEELFDILNLLDSFLKSSSPGVVMGATK---LFLILAKMFPH-VQ 270
Query: 323 PNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDV 382
++LVR L L ++AL + + S H +H + + +
Sbjct: 271 TDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGH--FSSHYKKFFCSYSEPHYI 328
Query: 383 SVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYV 442
+++ V++L + + N Q++ E+ Y + + + +A Y +
Sbjct: 329 KLQK--VEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIFAIGGIARTYTDQCVQIL 386
Query: 443 DTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGG-- 500
+L L + E + V+Q + + + V +AL P C EN+ G
Sbjct: 387 TELLGLRQ-------EHITTVVVQTFRDLVWLCPQCTEAVCQAL--PGCEENIQDSEGKQ 437
Query: 501 ---YILGEFGNLIAGDP 514
++LG G I P
Sbjct: 438 ALIWLLGVHGERIPNAP 454
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 38.1 bits (87), Expect = 0.039
Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 5/78 (6%)
Query: 629 DTKRDRSVDVNGGPEPAPASTSAVSTPSP-----SADLLGLGAAPPAPAGPPPSSGGSGL 683
D+ RD + P P P S P P +A LG APP P PPP G
Sbjct: 75 DSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFP 134
Query: 684 LVDVFSDSASVVAPLAPG 701
++ S + P PG
Sbjct: 135 VISSSMGSPGLPPPAPPG 152
>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
sapiens]
Length = 907
Score = 37.4 bits (85), Expect = 0.066
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 10/112 (8%)
Query: 598 LEEMPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAV--STP 655
LE P S + L K +TVT T +++D + + +++AV ST
Sbjct: 285 LEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPA-KTIDTSPPVDLFATASAAVPVSTS 343
Query: 656 SPSADLLGL-------GAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAP 700
PS+DLL L GAA A PPP +GG+ D+ + + P
Sbjct: 344 KPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVP 395
Score = 35.4 bits (80), Expect = 0.25
Identities = 39/110 (35%), Positives = 49/110 (44%), Gaps = 16/110 (14%)
Query: 590 STDILATVLEEMPP---FPERESSILAKLKKKKG---PSTVTDLEDTKRDRS--VDVNG- 640
S D+ +T PP P ESS+ A L PS T K D S +D+ G
Sbjct: 585 SIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGD 644
Query: 641 -----GPEPAPASTSAVSTPSPSADLL-GLGAAPPAPAGPPPSSGGSGLL 684
EP PAS A S+ S SADLL G G + AP+ P + + LL
Sbjct: 645 AFGSSASEPQPAS-QAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLL 693
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 37.4 bits (85), Expect = 0.066
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 618 KKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPS 677
KK S+ D + D GGP P P P+PS G G P+PAG P +
Sbjct: 174 KKSDSSRDDESKEAKSTDPDSTGGPGPNP-------NPTPSCGANGGGGGGPSPAGAPGA 226
Query: 678 SGGSG 682
+G G
Sbjct: 227 AGPGG 231
>gi|151301137 AT-hook transcription factor [Homo sapiens]
Length = 1439
Score = 37.0 bits (84), Expect = 0.086
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 620 GPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSG 679
GP + T + R + P P S A S+P P L L APPAPA PP +
Sbjct: 1285 GPGSATSGAEKATTRR-KASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPA-PPAFAY 1342
Query: 680 GSGLLVDVFSDSASVVAPLAPGSEDNFARF 709
S + + + +A AP P S A++
Sbjct: 1343 ISSVPIMPYPPAAVYYAPAGPTSAQPAAKW 1372
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 36.6 bits (83), Expect = 0.11
Identities = 43/131 (32%), Positives = 57/131 (43%), Gaps = 28/131 (21%)
Query: 590 STDILATV-LEEMPPFPERE------SSILAKLKKKKGPSTV-TDLED-----------T 630
ST + T+ + PP P+ E SS+L K +K TV LE T
Sbjct: 494 STQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTT 553
Query: 631 KRDRSVD--VNGGPEPAPASTSAVSTP----SPSADLLGLGAAPPAPAGPPPSSGGSGLL 684
K+D +V V P+ +P+ S S+P SP A L P P G P SS S L
Sbjct: 554 KKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG 613
Query: 685 VDVFSDSASVV 695
V + SASV+
Sbjct: 614 V---NSSASVI 621
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 36.2 bits (82), Expect = 0.15
Identities = 45/174 (25%), Positives = 60/174 (34%), Gaps = 28/174 (16%)
Query: 549 NLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEM------- 601
NL P+++ S++QL +A+ L + L V +EM
Sbjct: 262 NLDPDLRSLFSRAGISEAQLTDAETSK-------LIYDFIEDQGGLEAVRQEMRRQEPLP 314
Query: 602 -PPFPERESS------ILAKLKKKKGPSTVTDL-----EDTKRDRSVDVNGGPEPAPAST 649
PP P R + I+ K + GP L T R GGP P P
Sbjct: 315 PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPA 374
Query: 650 SAVS--TPSPSADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAPG 701
+ S P P G PP P PPP S G+G + LAPG
Sbjct: 375 TGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPG 428
>gi|158303333 synaptopodin isoform B [Homo sapiens]
Length = 685
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 4/66 (6%)
Query: 643 EPAPASTSAVSTPSPSA-DL---LGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPL 698
EPA S A S PS+ DL L GA PP+PA P PS GL DS A
Sbjct: 579 EPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638
Query: 699 APGSED 704
P D
Sbjct: 639 PPYGGD 644
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 4/66 (6%)
Query: 643 EPAPASTSAVSTPSPSA-DL---LGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPL 698
EPA S A S PS+ DL L GA PP+PA P PS GL DS A
Sbjct: 579 EPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638
Query: 699 APGSED 704
P D
Sbjct: 639 PPYGGD 644
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 35.8 bits (81), Expect = 0.19
Identities = 18/42 (42%), Positives = 20/42 (47%)
Query: 642 PEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSGGSGL 683
P P P +SA P P L APP P GPPP+ GL
Sbjct: 687 PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGL 728
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 35.4 bits (80), Expect = 0.25
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 645 APASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAPG 701
+P S S PS +D G G +P P PPP++ G G + A+ AP PG
Sbjct: 221 SPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPG----AHASGAAGTAPAPPG 273
Score = 35.4 bits (80), Expect = 0.25
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 601 MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDR-SVDVNGGPEPAPAS----TSAVSTP 655
+PP P ++S A GP D +R +V G P PAPA SA +T
Sbjct: 415 VPPAPPAQASFGAF----SGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATE 470
Query: 656 SPSADLLGLGAAPPAPAGPPPS 677
D G A PAP P PS
Sbjct: 471 GGGGDCADAGTAGPAPPPPAPS 492
Score = 31.2 bits (69), Expect = 4.7
Identities = 14/40 (35%), Positives = 16/40 (40%)
Query: 640 GGPEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSG 679
GG P P + P A G PAP G PP+ G
Sbjct: 240 GGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPG 279
>gi|171184447 myozenin 3 [Homo sapiens]
Length = 251
Score = 35.0 bits (79), Expect = 0.33
Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 8/122 (6%)
Query: 559 QDVLRSDSQLRNADVEL----QQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAK 614
QD++ + LRN L +QR V+ AS + ES +A
Sbjct: 34 QDLMMEELSLRNNRGSLLFQKRQRRVQKFTFELAASQRAMLAGSARRKVTGTAESGTVAN 93
Query: 615 LKKKKGPSTVTDLEDTKRDRSVDVNGGPEPA-PASTSAVSTPSPSADLLGLGAAPPAPAG 673
+GP+ ++L + GGPE A PA+ A PSPSA L G A P
Sbjct: 94 ANGPEGPNYRSELHIFPASPGASL-GGPEGAHPAAAPAGCVPSPSA--LAPGYAEPLKGV 150
Query: 674 PP 675
PP
Sbjct: 151 PP 152
>gi|171184445 myozenin 3 [Homo sapiens]
Length = 251
Score = 35.0 bits (79), Expect = 0.33
Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 8/122 (6%)
Query: 559 QDVLRSDSQLRNADVEL----QQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAK 614
QD++ + LRN L +QR V+ AS + ES +A
Sbjct: 34 QDLMMEELSLRNNRGSLLFQKRQRRVQKFTFELAASQRAMLAGSARRKVTGTAESGTVAN 93
Query: 615 LKKKKGPSTVTDLEDTKRDRSVDVNGGPEPA-PASTSAVSTPSPSADLLGLGAAPPAPAG 673
+GP+ ++L + GGPE A PA+ A PSPSA L G A P
Sbjct: 94 ANGPEGPNYRSELHIFPASPGASL-GGPEGAHPAAAPAGCVPSPSA--LAPGYAEPLKGV 150
Query: 674 PP 675
PP
Sbjct: 151 PP 152
>gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]
Length = 1035
Score = 35.0 bits (79), Expect = 0.33
Identities = 41/150 (27%), Positives = 60/150 (40%), Gaps = 23/150 (15%)
Query: 567 QLRNADVELQQRAVEYLRLSTVASTDILATVLEE-----MPPFPERESSILAKLKKKKGP 621
Q + + + +Q E R V ++L +L++ +PP P + A L K+ G
Sbjct: 711 QQQQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSPPPLWAGLAKQ-GL 769
Query: 622 STVTDLE-DTKRDRSVDVNGGPEPAPASTSAVSTPSPSADLLGLGAAP---------PAP 671
S T LE + +R + +P P + P+ L GLG AP P
Sbjct: 770 SMKTLLELQLEGERQLH----KQPPPREPARAQAPNHRVQLGGLGTAPLNQWVSEAGPLW 825
Query: 672 AGPPPSSGGS---GLLVDVFSDSASVVAPL 698
GP S GGS GL D S+V L
Sbjct: 826 GGPDKSGGGSSGLGLWEDTPKSGGSLVRGL 855
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 35.0 bits (79), Expect = 0.33
Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 13/51 (25%)
Query: 641 GPEPAPASTSAVSTPSPSADLLGLGAAPPAPAGP------PPS---SGGSG 682
GP+ +PA + TP+P A + APPAP+GP PPS SGG G
Sbjct: 354 GPKASPAPSHNSGTPAPYAQAV----APPAPSGPSTTQPRPPSVQPSGGGG 400
Score = 33.5 bits (75), Expect = 0.95
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 589 ASTDILATVLEEMPPFPERESSILAKLKKKKGPSTVTDLEDT---KRDRSVDVNGGPEPA 645
+ST T +PP P ++ ++ KK+G ST +++ + + V N P+
Sbjct: 258 SSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSP 317
Query: 646 PASTSAVSTPSPSADLLGL---GAAPPAPAGPPPSSGGSGLLVDVFSDS-----ASVVAP 697
+ S P P+A L PAPA PP + G + A VAP
Sbjct: 318 AVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAP 377
Query: 698 LAP 700
AP
Sbjct: 378 PAP 380
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 34.7 bits (78), Expect = 0.43
Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 11/70 (15%)
Query: 614 KLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSADLLGLGAAPPAPAG 673
KL +KG S D D G P +P + TPSP+ + A PP PA
Sbjct: 265 KLSPRKGKSKTLDNSDLHP-------GPPAGSPPPLTLPPTPSPATAVTAASAQPPGPAP 317
Query: 674 P----PPSSG 679
P PP+ G
Sbjct: 318 PITLEPPAPG 327
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,628,843
Number of Sequences: 37866
Number of extensions: 1645076
Number of successful extensions: 10281
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 9586
Number of HSP's gapped (non-prelim): 817
length of query: 939
length of database: 18,247,518
effective HSP length: 112
effective length of query: 827
effective length of database: 14,006,526
effective search space: 11583397002
effective search space used: 11583397002
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.