Guide to the Human Genome
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Search of human proteins with 27436966

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27436966 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 1 [Homo sapiens]
         (419 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27436966 potassium voltage-gated channel, shaker-related subf...   837   0.0  
gi|27436962 potassium voltage-gated channel, shaker-related subf...   673   0.0  
gi|27436964 potassium voltage-gated channel, shaker-related subf...   672   0.0  
gi|27436969 potassium voltage-gated channel, shaker-related subf...   587   e-168
gi|4504825 potassium voltage-gated channel, shaker-related subfa...   583   e-167
gi|27436971 potassium voltage-gated channel, shaker-related subf...   520   e-147
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s...    84   3e-16
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]     81   2e-15
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]     80   3e-15
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s...    61   2e-09
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]     44   2e-04
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]      44   2e-04
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]      44   4e-04
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]     42   0.001
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]      42   0.001
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]      39   0.007
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]     39   0.009
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...    37   0.044
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]          35   0.13 
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]     33   0.48 
gi|120953251 neuron navigator 3 [Homo sapiens]                         32   1.4  
gi|42542392 CCAAT/enhancer binding protein zeta [Homo sapiens]         31   2.4  
gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]        31   2.4  
gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]        31   2.4  
gi|60097902 filaggrin [Homo sapiens]                                   29   9.1  
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]      29   9.1  
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]           29   9.1  
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo...    29   9.1  
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo...    29   9.1  
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo...    29   9.1  

>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score =  837 bits (2162), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQL 60
           MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQL
Sbjct: 1   MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQL 60

Query: 61  ALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEV 120
           ALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEV
Sbjct: 61  ALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEV 120

Query: 121 AERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETE 180
           AERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETE
Sbjct: 121 AERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETE 180

Query: 181 RGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTS 240
           RGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTS
Sbjct: 181 RGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTS 240

Query: 241 RWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLAC 300
           RWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLAC
Sbjct: 241 RWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLAC 300

Query: 301 GIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAV 360
           GIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAV
Sbjct: 301 GIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAV 360

Query: 361 AWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 419
           AWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
Sbjct: 361 AWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 419


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score =  673 bits (1737), Expect = 0.0
 Identities = 335/349 (95%), Positives = 341/349 (97%)

Query: 71  YLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 130
           +L++  +S + TT   TGM +RNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE
Sbjct: 60  FLRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 119

Query: 131 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 190
           SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE
Sbjct: 120 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 179

Query: 191 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 250
           GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA
Sbjct: 180 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 239

Query: 251 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 310
           YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG
Sbjct: 240 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 299

Query: 311 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 370
           VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS
Sbjct: 300 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 359

Query: 371 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 419
           SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
Sbjct: 360 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score =  672 bits (1733), Expect = 0.0
 Identities = 341/380 (89%), Positives = 354/380 (93%), Gaps = 3/380 (0%)

Query: 42  AKDSSLSPSGESQLRA--RQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGL 99
           +K SS +P+  +  RA  R +A++    +  +     +S + +T   TGM +RNLGKSGL
Sbjct: 23  SKQSSTAPNVVNAARAKFRTVAIIAR-SLGTFTPQHHISLKESTAKQTGMKYRNLGKSGL 81

Query: 100 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKG 159
           RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKG
Sbjct: 82  RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKG 141

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219
           WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME
Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201

Query: 220 EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEV 279
           EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEV
Sbjct: 202 EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEV 261

Query: 280 QLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQN 339
           QLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQN
Sbjct: 262 QLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQN 321

Query: 340 KLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHV 399
           KLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHV
Sbjct: 322 KLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHV 381

Query: 400 VNEIDNILRNKPYSKKDYRS 419
           VNEIDNILRNKPYSKKDYRS
Sbjct: 382 VNEIDNILRNKPYSKKDYRS 401


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score =  587 bits (1512), Expect = e-168
 Identities = 279/332 (84%), Positives = 316/332 (95%)

Query: 88  GMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKA 147
           GM +RNLGKSGLRVSCLGLGTWVTFGGQI+DE+AE+LMT+AY++G+NLFDTAEVYAAGKA
Sbjct: 22  GMIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKA 81

Query: 148 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVV 207
           EV+LG+IIKKKGWRRSSLVITTK++WGGKAETERGLSRKHIIEGLK SL+RLQLEYVDVV
Sbjct: 82  EVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVV 141

Query: 208 FANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQA 267
           FANRPD NTPMEE VRAMTHVINQGMAMYWGTSRWS+MEIMEAYSVARQFN+ PP+CEQA
Sbjct: 142 FANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQA 201

Query: 268 EYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKE 327
           EYH+FQREKVEVQLPEL+HKIGVGAMTWSPLACGI+SGKY +G+P  SRASLK YQWLK+
Sbjct: 202 EYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKD 261

Query: 328 RIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLG 387
           +I+SEEGR+QQ KLK+L  IAERLGCTLPQLA+AWCLRNEGVSSVLLG+S  +QL+EN+G
Sbjct: 262 KILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIG 321

Query: 388 AIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 419
           AIQVLPK++S +++EID+IL NKPYSKKDYRS
Sbjct: 322 AIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS 353


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score =  583 bits (1504), Expect = e-167
 Identities = 277/329 (84%), Positives = 314/329 (95%)

Query: 91  HRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVI 150
           +RNLGKSGLRVSCLGLGTWVTFGGQI+DE+AE+LMT+AY++G+NLFDTAEVYAAGKAEV+
Sbjct: 39  YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVV 98

Query: 151 LGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFAN 210
           LG+IIKKKGWRRSSLVITTK++WGGKAETERGLSRKHIIEGLK SL+RLQLEYVDVVFAN
Sbjct: 99  LGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN 158

Query: 211 RPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYH 270
           RPD NTPMEE VRAMTHVINQGMAMYWGTSRWS+MEIMEAYSVARQFN+ PP+CEQAEYH
Sbjct: 159 RPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYH 218

Query: 271 LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIV 330
           +FQREKVEVQLPEL+HKIGVGAMTWSPLACGI+SGKY +G+P  SRASLK YQWLK++I+
Sbjct: 219 MFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKIL 278

Query: 331 SEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQ 390
           SEEGR+QQ KLK+L  IAERLGCTLPQLA+AWCLRNEGVSSVLLG+S  +QL+EN+GAIQ
Sbjct: 279 SEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQ 338

Query: 391 VLPKMTSHVVNEIDNILRNKPYSKKDYRS 419
           VLPK++S +++EID+IL NKPYSKKDYRS
Sbjct: 339 VLPKLSSSIIHEIDSILGNKPYSKKDYRS 367


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score =  520 bits (1338), Expect = e-147
 Identities = 248/329 (75%), Positives = 292/329 (88%)

Query: 87  TGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK 146
           TGM +RNLGKSGLRVSCLGLGTWVTFG QISDE AE ++T+AYE GVNLFDTAEVYAAGK
Sbjct: 76  TGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGK 135

Query: 147 AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV 206
           AE  LG+I+K KGWRRSS VITTK++WGG+AETERGLSRKHIIEGL+GSL+RLQL YVD+
Sbjct: 136 AERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195

Query: 207 VFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 266
           VFANR D N PMEEIVRAMT+VINQG+A+YWGTSRW A EIMEAYS+ARQFN+IPPVCEQ
Sbjct: 196 VFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQ 255

Query: 267 AEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLK 326
           AE+HLFQREKVE+QLPELYHKIGVG++TW PLACG+I+ KY   VP++ RAS+K YQWLK
Sbjct: 256 AEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLK 315

Query: 327 ERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENL 386
           +++ SE+G+KQQ K+ DL P+A +LGCT+ QLA+AWCLR+EGVSSVLLG S+ EQLIE+L
Sbjct: 316 DKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHL 375

Query: 387 GAIQVLPKMTSHVVNEIDNILRNKPYSKK 415
           GA+QVL ++T   V EID +L NKP+SKK
Sbjct: 376 GALQVLSQLTPQTVMEIDGLLGNKPHSKK 404


>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
           sapiens]
          Length = 331

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 78/296 (26%), Positives = 138/296 (46%), Gaps = 25/296 (8%)

Query: 114 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 172
           G+  D      +T A+ E G    DTA +Y+ G++E ILG +  + G     + I TK  
Sbjct: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79

Query: 173 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 231
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EE +RA   +  +
Sbjct: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134

Query: 232 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVG 291
           G  +  G S ++A E+ E  ++ +    I P   Q  Y    R+ VE +L       G+ 
Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQ-VETELFPCLRHFGLR 193

Query: 292 AMTWSPLACGIISGKYGNGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIAE 349
              ++PLA G+++GKY     +  +   + +  QW +   +      +++  + ++ + +
Sbjct: 194 FYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGTQWAE---IYRNHFWKEHHFEGIALVEK 250

Query: 350 RL----GCTLPQL---AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 393
            L    G + P +   A+ W      L+     +V+LG S+ EQL +NL A +  P
Sbjct: 251 ALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306


>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
          Length = 331

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 80/293 (27%), Positives = 130/293 (44%), Gaps = 19/293 (6%)

Query: 114 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 172
           G+  D      +T A+ E G    DTA VY+ G++E ILG +  + G     + I TK  
Sbjct: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79

Query: 173 WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQG 232
                     L    +   L+ SL+RLQ   VD+ + + PD +TP+EE +RA   +  +G
Sbjct: 80  ----PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEG 135

Query: 233 MAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGA 292
             +  G S ++A E+ E  ++ +    I P   Q  Y+   R+ VE +L       G+  
Sbjct: 136 KFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGLRF 194

Query: 293 MTWSPLACGIISGKY----GNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIA 348
             ++PLA G+++GKY     NG     R     +  +      +E   +   L +   + 
Sbjct: 195 YAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVE-KALQ 253

Query: 349 ERLGCTLPQLAVA---WC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 393
              G + P +  A   W      L+     +V+LG S+ EQL +NL A +  P
Sbjct: 254 AAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306


>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
          Length = 359

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 77/282 (27%), Positives = 126/282 (44%), Gaps = 30/282 (10%)

Query: 130 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY-WGGKAETERGLSRKHI 188
           E G    DTA +Y+ G++E ILG +    G     + I TK   W GK+     L    +
Sbjct: 65  ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119

Query: 189 IEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIM 248
              L+ SL+RLQ   VD+ + + PD  TP+EE + A   +  +G  +  G S +++ E+ 
Sbjct: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179

Query: 249 EAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYG 308
           E  ++ +    I P   Q  Y+   R+ VE +L       G+    ++PLA G+++GKY 
Sbjct: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238

Query: 309 NGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIA-------ERLGCTLPQL- 358
               +  +   + +   W      +E  R +  K      IA          G + P + 
Sbjct: 239 YEDKDGKQPVGRFFGNSW------AETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVT 292

Query: 359 --AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 393
             A+ W      L+     +V+LG S+ EQL +NL A +  P
Sbjct: 293 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334


>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
           sapiens]
          Length = 249

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 7/155 (4%)

Query: 114 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 172
           G+  D      +T A+ E G    DTA +Y+ G++E ILG +  + G     + I TK  
Sbjct: 20  GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79

Query: 173 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 231
            W G +     L    +   L+ SL+RLQ   VD+ + + PD + P+EE +RA   +  +
Sbjct: 80  PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134

Query: 232 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 266
           G  +  G S ++A E+ E  ++ +    I P   Q
Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%)

Query: 97  SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 156
           +G ++  +GLGTW +  GQ+   V       A   G    D A +Y     E  +G  +K
Sbjct: 10  TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61

Query: 157 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 211
           +     K   R  L +T+KL W  K   E       +   L+ +L  LQLEY+D+   + 
Sbjct: 62  EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114

Query: 212 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252
           P +                   +T  +E  +A+  ++ +G+    G S +++ +I +  S
Sbjct: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174

Query: 253 VARQFNMIPPVCEQAEYH 270
           VA     + P   Q E H
Sbjct: 175 VA----SVRPAVLQVECH 188


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%)

Query: 97  SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 156
           +G ++  +GLGTW +  GQ+   V       A   G    D A +Y     E  +G  +K
Sbjct: 10  TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61

Query: 157 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 211
           +     K   R  L +T+KL W  K   E       +   L+ +L  LQLEY+D+   + 
Sbjct: 62  EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114

Query: 212 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252
           P +                   +T  +E  +A+  ++ +G+    G S +++ +I +  S
Sbjct: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174

Query: 253 VARQFNMIPPVCEQAEYH 270
           VA     + P   Q E H
Sbjct: 175 VA----SVRPAVLQVECH 188


>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 52/234 (22%), Positives = 99/234 (42%), Gaps = 45/234 (19%)

Query: 89  MPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA-AGKA 147
           M  R L  +G ++  LGLGTW +  GQ+++ V      +A + G    D A VY    + 
Sbjct: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAV-----KVAIDVGYRHIDCAHVYQNENEV 55

Query: 148 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLEY 203
            V +   ++++  +R  L I +KL+       E+GL        +KG+ Q+    L+L+Y
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL--------VKGACQKTLSDLKLDY 104

Query: 204 VDVVFANRPDSNTPMEEIV-------------------RAMTHVINQGMAMYWGTSRWSA 244
           +D+   + P    P +E                      AM  ++++G+    G S ++ 
Sbjct: 105 LDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH 164

Query: 245 MEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 298
           +++     + +      P   Q E H +  ++   +L +     G+    +SPL
Sbjct: 165 LQV--EMILNKPGLKYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPL 213


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
           LG GT+     ++    A   + +A E+G +  D+A VY     E  +G  I+ K     
Sbjct: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126

Query: 220 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 259
           E++       ++   + + T    + W AME  +   +A+   +                
Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181

Query: 260 --IPPVCEQAEYHLFQREK 276
               PVC Q E H +  ++
Sbjct: 182 LKYKPVCNQVECHPYFNQR 200


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
           LG GT+     ++    A   + +A E+G +  D+A VY     E  +G  I+ K     
Sbjct: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126

Query: 220 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 259
           E++       ++   + + T    + W AME  +   +A+   +                
Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181

Query: 260 --IPPVCEQAEYHLFQREK 276
               PVC Q E H +  ++
Sbjct: 182 LKYKPVCNQVECHPYFNQR 200


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
           LG GT+     ++    A     +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126

Query: 220 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVA----------RQFNMI----- 260
           E++       ++   + + T    + W A+E  +   +A          RQ  MI     
Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181

Query: 261 ---PPVCEQAEYHLFQREK 276
               PVC Q E H +  ++
Sbjct: 182 LKYKPVCNQVECHPYFNQR 200


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 44/201 (21%)

Query: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRPDSNTPM 218
            +R  +  T+KL+            R  ++   L+ SL++ QL+YVD+   + P S  P 
Sbjct: 74  VKREDIFYTSKLW--------STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125

Query: 219 EEIVRAMTHVINQGMAMYWGT---SRWSAMEIMEAYSVA----------RQFNMI----- 260
           EE    ++     G  ++      + W AME  +   +A          RQ  MI     
Sbjct: 126 EE----LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181

Query: 261 ---PPVCEQAEYH-LFQREKV 277
               PVC Q E H  F R K+
Sbjct: 182 LKYKPVCNQVECHPYFNRSKL 202


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score = 36.6 bits (83), Expect = 0.044
 Identities = 50/220 (22%), Positives = 92/220 (41%), Gaps = 39/220 (17%)

Query: 100 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEV--ILGSIIKK 157
           ++  +GLGTW +  G++ + V      +A ++     D A  Y   + EV   +   I++
Sbjct: 12  KMPIVGLGTWRSLLGKVKEAV-----KVAIDAEYRHIDCAYFY-ENQHEVGEAIQEKIQE 65

Query: 158 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP----- 212
           K   R  L I +K++       ER L RK      + +L+ L+L Y+DV   + P     
Sbjct: 66  KAVMREDLFIVSKVW---PTFFERPLVRK----AFEKTLKDLKLSYLDVYLIHWPQGFKT 118

Query: 213 -DSNTPME-------------EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 258
            D   P +             +   AM  ++++G+    G S ++  +I    +  +   
Sbjct: 119 GDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLN--KPGL 176

Query: 259 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 298
              PV  Q E H +  ++   +L +  H  G+    +SPL
Sbjct: 177 KYKPVTNQVECHPYLTQE---KLIQYCHSKGITVTAYSPL 213


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 16/115 (13%)

Query: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
           LG GT+     ++    A   + +A E+G +  D+A VY     E  +G  I+ K     
Sbjct: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDS 214
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S
Sbjct: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVS 121


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 47/195 (24%)

Query: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73

Query: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP------D 213
            +R  +  T+KL+             + +   L+ SL++LQL+YVD+   + P      +
Sbjct: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126

Query: 214 SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVA----------RQFNMI--- 260
           +  P +E  + +   ++        ++ W  ME  +   +A          RQ  MI   
Sbjct: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179

Query: 261 -----PPVCEQAEYH 270
                 PVC Q E H
Sbjct: 180 PGLKYKPVCNQVECH 194


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 4   ARTGAAGS--QISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGES 53
           +R  AAGS  ++   +   RR   F+   K+K P  A+ N KDSS  P   S
Sbjct: 252 SRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSS 303


>gi|42542392 CCAAT/enhancer binding protein zeta [Homo sapiens]
          Length = 1054

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 15/42 (35%), Positives = 22/42 (52%)

Query: 11  SQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGE 52
           S++S + +K +    F  AG  + P+K   N  DSSL  S E
Sbjct: 939 SKVSTKKSKRKGTDDFDFAGSFQGPRKKKRNLNDSSLFVSAE 980


>gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]
          Length = 758

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 292 AMTWSPLACGIISGKYGNGV-PESSRASLKCYQWLKERIVSEEGRKQQNKL 341
           A +WSP +    S   G    P ++ A+L   Q L+ER+   E RKQQ +L
Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEEL 156


>gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]
          Length = 758

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 292 AMTWSPLACGIISGKYGNGV-PESSRASLKCYQWLKERIVSEEGRKQQNKL 341
           A +WSP +    S   G    P ++ A+L   Q L+ER+   E RKQQ +L
Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEEL 156


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 3    AARTGAAGS---QIS--EENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRA 57
            A R+G +GS   Q+S  E++     ++G S  G+  S  K + ++   S S  G+  +  
Sbjct: 2405 AGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHG 2464

Query: 58   RQLALLREVEMNWYLKLCDLS----SEHTTVCTTGMPHRNLGKSGLR 100
               +     + + Y +L D S    S H+   + G    + G SG R
Sbjct: 2465 HPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSR 2511


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 41/168 (24%), Positives = 69/168 (41%), Gaps = 27/168 (16%)

Query: 91  HRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVI 150
           HR     G  +  +GLGT+           A  +  +A ++G    D A +Y   + E  
Sbjct: 8   HRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVK-VAIDTGYRHIDGAYIY---QNEHE 63

Query: 151 LGSIIKKK----GWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLE 202
           +G  I++K      RR  +    KL+           +  H+ E ++ +L+R    LQL+
Sbjct: 64  VGEAIREKIAEGKVRREDIFYCGKLW-----------ATNHVPEMVRPTLERTLRVLQLD 112

Query: 203 YVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 250
           YVD+     P +  P +EI          G  +Y  ++  +  E MEA
Sbjct: 113 YVDLYIIEVPMAFKPGDEIYPR----DENGKWLYHKSNLCATWEAMEA 156


>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
          Length = 1194

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 16/85 (18%)

Query: 21  RRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQLALLREVEMNWYLKLCDLSSE 80
           RR+SG    GKD   +  +     + L P G+S    R+ A L E       ++C L   
Sbjct: 204 RRRSGLEEPGKDGDGQTLA-----NGLGPGGDSN---RRTAELEEALERQRAEVCQLRER 255

Query: 81  HTTVC--------TTGMPHRNLGKS 97
              +C          G  HR LGK+
Sbjct: 256 LAVLCRQMSQLEEELGTAHRELGKA 280


>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
           sapiens]
          Length = 890

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 275 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 334
           E  ++ LP L  ++   +   SP+       K+    PE  R   + +Q  +ER++ E  
Sbjct: 569 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 625

Query: 335 RKQQNKLKD 343
           +K+Q+KLK+
Sbjct: 626 QKEQDKLKE 634


>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
           sapiens]
          Length = 902

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 275 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 334
           E  ++ LP L  ++   +   SP+       K+    PE  R   + +Q  +ER++ E  
Sbjct: 581 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 637

Query: 335 RKQQNKLKD 343
           +K+Q+KLK+
Sbjct: 638 QKEQDKLKE 646


>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
           sapiens]
          Length = 1056

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 275 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 334
           E  ++ LP L  ++   +   SP+       K+    PE  R   + +Q  +ER++ E  
Sbjct: 735 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 791

Query: 335 RKQQNKLKD 343
           +K+Q+KLK+
Sbjct: 792 QKEQDKLKE 800


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,175,671
Number of Sequences: 37866
Number of extensions: 645399
Number of successful extensions: 1716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1687
Number of HSP's gapped (non-prelim): 42
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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