Guide to the Human Genome
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Name: AKR1C2 Sequence: fasta or formatted (323aa) NCBI GI: 4503285
Description:

aldo-keto reductase family 1, member C2

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Bile Acids and Other Cholesterol Derivatives

Other entries for this name:
alt mRNA [323aa] aldo-keto reductase family 1, member C2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.1         23           1
 C cysteine            2.2          7           1
 D aspartate           5.6         18           1
 E glutamate           7.1         23           2
 F phenylalanine       4.0         13           1
 G glycine             4.6         15           1
 H histidine           3.1         10           2
 I isoleucine          4.6         15           1
 K lysine              8.0         26           2
 L leucine            11.1         36           2
 M methionine          1.5          5           1
 N asparagine          5.3         17           2
 P proline             5.9         19           2
 Q glutamine           3.4         11           1
 R arginine            4.6         15           1
 S serine              5.9         19           1
 T threonine           2.2          7           1
 V valine              8.4         27           3
 W tryptophan          0.9          3           1
 Y tyrosine            4.3         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   aldo-keto reductase family 1, member C2 
AKR1C2                1.000   aldo-keto reductase family 1, member C2 
AKR1C1                0.976   aldo-keto reductase family 1, member C1 
AKR1C3                0.874   aldo-keto reductase family 1, member C3 
AKR1C4                0.825   aldo-keto reductase family 1, member C4 
AKR1D1                0.584   aldo-keto reductase family 1, member D1 
AKR1B1                0.465   aldo-keto reductase family 1, member B1 
AKR1B10               0.445   aldo-keto reductase family 1, member B10 
AKR1B10L              0.424   aldo-keto reductase family 1, member B10-like [Homo...
AKR1A1                0.386   aldo-keto reductase family 1, member A1 
AKR1A1                0.386   aldo-keto reductase family 1, member A1 
AKR1CL2               0.386   aldo-keto reductase family 1, member C-like 2 
LOC100134257          0.356   hypothetical protein LOC100134257 
AKR7L                 0.046   aflatoxin B1 aldehyde reductase 3 isoform 2 
AKR7L                 0.046   aflatoxin B1 aldehyde reductase 3 isoform 1 
AKR7A3                0.043   aldo-keto reductase family 7, member A3 
AKR7A2                0.038   aldo-keto reductase family 7, member A2 
KCNAB1                0.027   potassium voltage-gated channel, shaker-related subf...
KCNAB1                0.027   potassium voltage-gated channel, shaker-related subf...
KCNAB1                0.027   potassium voltage-gated channel, shaker-related subf...
KCNAB2                0.021   potassium voltage-gated channel, shaker-related subfa...
KCNAB2                0.021   potassium voltage-gated channel, shaker-related subf...
KCNAB3                0.016   potassium voltage-gated channel, shaker-related subf...
EIF2B1                0.009   eukaryotic translation initiation factor 2B, subunit ...
AFF4                  0.008   ALL1 fused gene from 5q31 
NSDHL                 0.006   NAD(P) dependent steroid dehydrogenase-like 
NSDHL                 0.006   NAD(P) dependent steroid dehydrogenase-like 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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