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Search of human proteins with 27262649
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
(1097 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] 2256 0.0
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 2151 0.0
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] 2151 0.0
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 2113 0.0
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] 2112 0.0
gi|171543895 ataxin 2 [Homo sapiens] 610 e-174
gi|163965366 nascent polypeptide-associated complex alpha subuni... 111 3e-24
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 104 5e-22
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 98 4e-20
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 95 3e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 90 1e-17
gi|55750053 atrophin-1 [Homo sapiens] 82 2e-15
gi|55750041 atrophin-1 [Homo sapiens] 82 2e-15
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 82 4e-15
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 82 4e-15
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 80 1e-14
gi|150170670 piccolo isoform 2 [Homo sapiens] 80 1e-14
gi|150378539 piccolo isoform 1 [Homo sapiens] 80 1e-14
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 79 2e-14
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 74 8e-13
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 74 8e-13
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 74 8e-13
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 73 1e-12
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 73 1e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 73 1e-12
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 73 1e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 72 3e-12
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 72 4e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 71 6e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 71 6e-12
>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
Length = 1097
Score = 2256 bits (5847), Expect = 0.0
Identities = 1097/1097 (100%), Positives = 1097/1097 (100%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAA 1080
YPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAA
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAA 1080
Query: 1081 PLPTASPALSDPDCLLT 1097
PLPTASPALSDPDCLLT
Sbjct: 1081 PLPTASPALSDPDCLLT 1097
>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
Length = 1062
Score = 2151 bits (5573), Expect = 0.0
Identities = 1046/1046 (100%), Positives = 1046/1046 (100%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046
YPYIGHPQGEQPGQAPGFPGGADDRI
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046
Score = 38.1 bits (87), Expect = 0.046
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67
P P P P Q + P PP G +P G A SA+ P P G
Sbjct: 977 PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036
Query: 68 GLRRGAEGILAPQPPP 83
G GA+ + P PPP
Sbjct: 1037 GFPGGADDRIPPLPPP 1052
>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
Length = 1075
Score = 2151 bits (5573), Expect = 0.0
Identities = 1046/1046 (100%), Positives = 1046/1046 (100%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046
YPYIGHPQGEQPGQAPGFPGGADDRI
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046
>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
Length = 1044
Score = 2113 bits (5476), Expect = 0.0
Identities = 1029/1032 (99%), Positives = 1029/1032 (99%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQGEQP 1032
YPYIGHPQ P
Sbjct: 1021 YPYIGHPQAPLP 1032
>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
Length = 1044
Score = 2112 bits (5473), Expect = 0.0
Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041
YPYIGHP Q Q P P G
Sbjct: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 610 bits (1574), Expect = e-174
Identities = 455/1196 (38%), Positives = 613/1196 (51%), Gaps = 225/1196 (18%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S
Sbjct: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118
A A S + G P G RG+++ KG PQS + F+G+Y
Sbjct: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263
Query: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178
N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+
Sbjct: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323
Query: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236
I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ +
Sbjct: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381
Query: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296
N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA
Sbjct: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441
Query: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356
QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR
Sbjct: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500
Query: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411
RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP
Sbjct: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560
Query: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446
++ P R A T + P +RP S PP P + P
Sbjct: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620
Query: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489
PR SPK SA IS+ PP +A P + + P + S GV
Sbjct: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680
Query: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527
+SP ASP+ + PT+ ++ P + P A
Sbjct: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738
Query: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579
P + + R Q Q + P+ + EN + P K E KG
Sbjct: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790
Query: 580 EKEVDGL------------LTSEPMGSPVSSKTE-------------------------- 601
K++D L TSE M ++ E
Sbjct: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850
Query: 602 ---SVSDKEDKPPLAPSGGTEGPEQPPPPCPS---QTGSPPVGLIKGEDKDEGPVAEQVK 655
S S K + P ++PS + + P S QT SP K + +++ AEQV+
Sbjct: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910
Query: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710
KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P
Sbjct: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968
Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
+ +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM
Sbjct: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019
Query: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826
A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+
Sbjct: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078
Query: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864
+H Q +VSSS QY + EQ A+YA ++ Q Y H
Sbjct: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136
Query: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915
LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH
Sbjct: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195
Query: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971
G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G
Sbjct: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254
Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
+ P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP
Sbjct: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303
Score = 39.3 bits (90), Expect = 0.021
Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%)
Query: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421
G + +R G + PPR L +PG A GP MS K Q+ + +
Sbjct: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174
Query: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479
+ + PPP A P S A+PA + P S+V +SSA+ P
Sbjct: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229
Query: 480 ---VTSSVSDPGVG 490
TS PG+G
Sbjct: 230 VVAATSGGGRPGLG 243
Score = 35.4 bits (80), Expect = 0.30
Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%)
Query: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401
A+R + L + R RGG ++ G P + PP GP SSP S+ G
Sbjct: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79
Query: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459
NG R L G L P RP +P P A PP +P A+P
Sbjct: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130
Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
AS P + A P P V P S+ P
Sbjct: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165
Score = 33.9 bits (76), Expect = 0.87
Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%)
Query: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70
Q ARR G G PGP ++A PPGP P +AS C G G R
Sbjct: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88
Query: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113
G+ +L PP PGA R G PP+S V
Sbjct: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 111 bits (278), Expect = 3e-24
Identities = 185/773 (23%), Positives = 253/773 (32%), Gaps = 126/773 (16%)
Query: 345 REGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRGPHHLDNSSPGPGSEARGIN 402
+EG P P ++ P + SS + R P +P P +P P +
Sbjct: 897 KEGPATPAP---KQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTP-PAATPPSPK 951
Query: 403 GGPSRMSPK-------AQRPL-RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAA 454
GGP+ SPK A P +G SP P+ + PP P G P SPK A
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--SPK-GA 1008
Query: 455 PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
P P + + P P S A+ P S P + +P SPK S A T + + + P
Sbjct: 1009 PTPPAVTPPSP------KGSPAATPFPKGASTP--PAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 515 GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLD---PFPPRI 571
TL + + G A P P P PP
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPP------------AATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631
PKG GL T G+P + S K P G P PP
Sbjct: 1109 TPPSPKG------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
Query: 632 TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHS 691
+PP KG K P+ K PT P + +P P+
Sbjct: 1163 LATPPP---KGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAP 1218
Query: 692 TPSIPVLTAGQSGLYSPQ-------YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKY 744
T + + GL +P + P GPA P+ P P + + P +G
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278
Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP 804
+ PP + + PP + A PP A TP ++ P +P+ PG P P
Sbjct: 1279 -----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTP----P 1328
Query: 805 MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864
P+ P P L + + P + +TP S E PTP A + P H
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPA-TTPSSKGGPTTPS--SKEGPTPPA-------ATPSH 1378
Query: 865 ATQLHAHQPQPATTPTGSQPQSQHAAP-----SPVQHQAGQAPHLGSGQPQQNLYHPGAL 919
P P P P+ +P SP + A G+ P + P A+
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 920 TGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH 979
TP SL P+ +P+ P++ G + VT PP
Sbjct: 1439 --TPVSLKKAPATSAPKGGPATPSS----------KGDPTLPAVT-----------PPSP 1475
Query: 980 PGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFP 1039
P P QV P+ P G P L A PS P + P P
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATP----APMGAPTLPAVIPS-----------SPKEVPATP 1520
Query: 1040 GGADDRILCRVGRSHSRRRQGLAPGSVLCFPPS----SLSCDPAAPLPTASPA 1088
D I + LAP L PP+ S PA P P +PA
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEAL-IPPAMTVPSPKKTPAIPTPKEAPA 1572
Score = 103 bits (257), Expect = 9e-22
Identities = 180/766 (23%), Positives = 242/766 (31%), Gaps = 158/766 (20%)
Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS----PKAQRPLRGAK----TLSSPS 426
G+S P S GP + ++ S + P+ +G+K T SP+
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857
Query: 427 NRPSGETSVPPPPAVGRMYPP--RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 484
P P P AV + P P P P + P P G A P + ++ +
Sbjct: 858 --PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
Query: 485 SDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEE 544
S P +PA I +P+ K T P+
Sbjct: 916 SSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPK----------------------- 951
Query: 545 LRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
++P P PP PKG G T P G+P S
Sbjct: 952 ----------GGPATPSPKWAPTPPAATPPSPKG------GPATPSPKGAPTPPAATPPS 995
Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP-PVGLIKGEDKDEGPVAEQVKKSTLNPNA 663
K +P G P P PS GSP KG K S
Sbjct: 996 PKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 664 KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV 723
+ PT P ++ P +P + TP P T P GPA
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTP--PAATP--------------PSPKGGPAT 1096
Query: 724 QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT- 782
+P+ P P + + P +G + PP + PA+ PP + A PP A T
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 783 -------PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR--MLTSGSHPQA 833
P P+ P PA P P + P + P T S
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 834 IVSSS---TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ-----PATTPTGSQPQ 885
+ + S P P+A P+P+ AT P A A P PAT P P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Query: 886 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 945
A P ++ PH G+ P TPPS GP+ P+ + PAA
Sbjct: 1266 PPAATPPSLKGGLATPPHKGA---------PNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 946 YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP----------PQ 995
P G + PP GAP PP V P P
Sbjct: 1317 -----PPSPKG----------------SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 996 SHGGP----------PQGAVP-QSGVPALSASTPSPYPYIGHPQGE--QPGQAPGFPGGA 1042
S GGP P A P G PA++ +P P I P+G+ P P P A
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 1043 DDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPA 1088
+ R G + + + L P +V P SL PA P PA
Sbjct: 1416 PATPVTREGAA-TPSKGDLTPPAV---TPVSLKKAPATSAPKGGPA 1457
Score = 97.1 bits (240), Expect = 8e-20
Identities = 188/775 (24%), Positives = 259/775 (33%), Gaps = 119/775 (15%)
Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRG-----PHHL 387
S + P+ S +G P P P+GG S +G P ++ P+G P
Sbjct: 972 SPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030
Query: 388 DNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPPPAVGRMY 445
S+P P + G P+ P A TL SP P+ + P PPA
Sbjct: 1031 GASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA---- 1085
Query: 446 PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTD 505
P SPK P P PP + P+ + P + +P SPK LA
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 506 VKELSTKEPGRTLEPQE-LA----RIAGKVPGLQNEQKRFQLEELRKFGAQFK---LQPS 557
K T P+ LA + A P + L GA PS
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 558 -----SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL 612
++P P P PKG GL T P G+P + S K
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 613 APSGGTEGPEQPPPPC------PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
P G P PP P G+P ++ GP K + P A
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318
Query: 667 NP-------------TKPLLSVNKSTSTPTSP--------GPRTHST---PSIPVLTAGQ 702
+P T P ++ TPT P GP T S+ P+ P T
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 703 SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA-----KGSLPPQRSD 757
G P P+ GPA+ +P+ P S +V K A +G+ P + D
Sbjct: 1379 KG--GPAMTPPSPK--RGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 758 QHQPASAPPMMQAAAAAGPPLVA-ATPYSSYIPYNPQQFPGQPAMMQPMAHYP----SQP 812
PA P ++ A A P ATP S P P P P+ +P A S P
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSP 1490
Query: 813 VFAPMLQSNPRMLTSGSHPQAIVSS--STPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
AP + P + + + P I SS P PS+ + + + P A
Sbjct: 1491 KKAP---ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 871 HQPQPATTP----TGSQPQSQHAAPSPVQHQAGQAP------HLGSGQPQQNLYHPGALT 920
P T P T + P + A +P +A P + G+ P++ L P A+T
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVT 1606
Query: 921 GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980
P P P A +P S PA P G VT + ++ T+
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPAT-------PAPKGTPTSPPVTPSSLKDSPTS------ 1653
Query: 981 GAPHPPQV---MLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032
P V M PQ+ G P P + L A P P I P + P
Sbjct: 1654 ----PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704
Score = 82.8 bits (203), Expect = 2e-15
Identities = 175/756 (23%), Positives = 247/756 (32%), Gaps = 120/756 (15%)
Query: 417 RGAKTLSSPSNRPSGETSVPPPPAVG---RMYPPRSPKSAAPAPISASCPEPPIGS---- 469
+G T+SS + PSG +V ++ + SP + P+ A P +G+
Sbjct: 383 KGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLV 442
Query: 470 --------AVPTSSASIP--VTSSVSDPGVGSISPASPK-ISLAPTDVKELSTKEPGRTL 518
A PT++ + V+ +S + +I P SP + +AP KE ST + TL
Sbjct: 443 VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST-QVATTL 501
Query: 519 ---------EPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF---------KLQPS--- 557
+P++L + V QK Q GA F K P+
Sbjct: 502 RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561
Query: 558 ---SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM--GSPVSSKTESVSDKEDKPPL 612
++P+NS E P E + EP+ G P SS T + +
Sbjct: 562 LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG-VNSSASV 620
Query: 613 APSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL------------- 659
+ GP+ P S +P V E D VA K T
Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
Query: 660 ------NPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISY 713
N KE T L S + P +P P+ P ++ A P+
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-------PEIPKS 733
Query: 714 IPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAA 773
+P + PA P S + P + S AS+ + A
Sbjct: 734 VPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792
Query: 774 AGPPL-VAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PSQPVFAPMLQSNPRMLTSGSH 830
+ PL V+ +P + P G P+ + P PV A L N
Sbjct: 793 SPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848
Query: 831 PQAIVSSSTPQYPSAEQPTPQALY-----------------ATVHQSYPHHATQLHAHQP 873
A S TP P PTP A+ + V+ +P A +
Sbjct: 849 SPATTHSPTPPSPKGA-PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 874 QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP-PSLPPGPSA 932
PA + T S P+ A P+P A +P P P TP P P P A
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 933 QSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992
+P S PA P G T + G A P GAP PP V
Sbjct: 968 ATPPSPKGGPAT-------PSPKGAPTPPAATPPSPKGG--PATPSPKGAPTPPAVT--- 1015
Query: 993 PPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQ-PGQAPGFPGGADDRILCRVG 1051
PP G P P+ +A+ PSP G P P AP P + G
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPK---GSPAATPLPKGAPTTPAAT---LPSPKG 1069
Query: 1052 RSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASP 1087
+ +G AP PPS PA P P +P
Sbjct: 1070 GPATPSLKG-APTPPAATPPSPKG-GPATPSPKGAP 1103
Score = 41.2 bits (95), Expect = 0.005
Identities = 160/759 (21%), Positives = 245/759 (32%), Gaps = 110/759 (14%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP----------PAVGRMYPPRSPKSAA 454
P + A P+ A ++++ +P ++PPP A + P SP + A
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAANQASPFPSPSTIA 74
Query: 455 PAPISASCPEPPIGSAVPTSSAS--------------IPVTSSVSDP-------GVGSIS 493
P+ P+ G+A+P +A P +++ P G S S
Sbjct: 75 STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134
Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELA------RIAGKVPGLQNEQKRFQLEELRK 547
++LAP V++ S P P +A I P +E K L K
Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK----TNLNK 190
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS------ 598
++ P +P PP I+ P + + S P +P ++
Sbjct: 191 VPSEVVPNPKGTPS------PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244
Query: 599 --KTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656
K ++S P S +GP PP T S PV + K GP
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV--VTSSQKTAGPNTPPDFP 302
Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQS--GLYSPQYISYI 714
+L + + S S GP S P++ ++ S G P S I
Sbjct: 303 ISLGSHLAPLHQ-----SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357
Query: 715 PQI----HMGPAVQAPQMYPYPVSNSVPGQQGKYR-GAKGSLPPQRSDQHQPASAPPMMQ 769
P + + PA A P + P GSL S P ++ +
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417
Query: 770 AA-AAAGPPLVAATPYSS-----YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR 823
+ A PLVA P SS + NP P +A S P + S P
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPP-----MSSGPI 472
Query: 824 MLTSGSHPQAIVSSS-TPQYPSAEQPTPQALYATVHQSYPHHATQLHAH--QPQPATTPT 880
+ P A+V + P+ PS + T + + P L + P
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532
Query: 881 GSQPQSQHAAP-SPVQHQAGQAPH-------LGSGQPQQNLYHPGALTGTPPSLPPGPSA 932
+ P S AP SP QAG L P+ + T + P +P P A
Sbjct: 533 QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQS--TSSSPEIPLSPEA 588
Query: 933 QSPQSSFPQPAAV-YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLL 991
+ S +P + P G + A V + G +A P + P V
Sbjct: 589 TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAF 648
Query: 992 HPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVG 1051
P +S P G P + S T + P++ P P G L
Sbjct: 649 -PLES--ADPAGVAPTT-AKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 1052 RSHSRRRQGLAPG-SVLCFPPSSLSCDPAAPLPTASPAL 1089
+ +AP C P ++L P P SP+L
Sbjct: 705 SENC----PVAPSPQNTCAPLATLVLAPEIPKSVPSPSL 739
Score = 41.2 bits (95), Expect = 0.005
Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 63/327 (19%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P P + SSP P G PS PK + + A T SP P+ PP P
Sbjct: 1571 PATPSSKEASSP-PAVTPSTYKGAPS---PK-ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 441 VGRMYP---------PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
G P P +P S +P S + +G+ VP +S +P +
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
Query: 492 ISPA--SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
++PA S I APT K TK+ T P P +N K
Sbjct: 1686 VAPAPESTPIITAPTR-KGPQTKKSSATSPP------ICPDPSAKNGSK----------- 1727
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDK 609
P +++ P P ++++ K D + + +P SK +
Sbjct: 1728 ---------GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST------- 1771
Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPT 669
PL + + +P S SPPV L P+A + P ++F P+
Sbjct: 1772 -PLTAAAFEKVLPKPESASVSAAPSPPVSL---------PLAPSPVPTL--PPKQQFLPS 1819
Query: 670 KPLLSVNKSTSTPTSPGPRTHSTPSIP 696
P L V +S S P +P P IP
Sbjct: 1820 SPGL-VLESPSKPLAPADEDELLPLIP 1845
Score = 39.7 bits (91), Expect = 0.016
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 9/122 (7%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGP-----PAAAS 56
P P P+ P PP+ + P G +PP P P + AA P P P AA+
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPG--AAAIGSARGQSTGKGPPQSPVF 114
P + A + L +GA A P P+ P A A + KG P +P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 115 EG 116
+G
Sbjct: 1100 KG 1101
Score = 39.7 bits (91), Expect = 0.016
Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 22/124 (17%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGG--TSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P+ P PP+ P GG T PP G P AT +P G A SP P
Sbjct: 1143 PPPKGAPTTPAATPPS-------PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 62 VAAAGS------GLR----RGAEGILAPQPPPPQQHQERP---GAAAIGSARGQSTGKGP 108
A + GL +GA A PP P+ P GA +A S GP
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255
Query: 109 PQSP 112
P
Sbjct: 1256 ATPP 1259
Score = 39.7 bits (91), Expect = 0.016
Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 6/112 (5%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
K P P + PP + + GT PP G P T +P G P P P
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPS 1355
Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS--TGKGPPQSP 112
+ G EG P P H+ P RG + + KG P SP
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Score = 38.5 bits (88), Expect = 0.035
Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 14/116 (12%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P P PP+ + PP G + P P P A PP A +P P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
Query: 62 VAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQSP 112
+ G GL +GA A PP P+ G A S +G +T P SP
Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSP 1205
Score = 38.5 bits (88), Expect = 0.035
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGP-LATSAAPPGPPAAASPCLGPV 62
P P P+ P PP+ + G +PP+ G P P + T +P G PA + P P
Sbjct: 1258 PPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 63 -AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
AA +G+ G P+ P PP P A S+ KG P +P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTP 1363
Score = 36.6 bits (83), Expect = 0.13
Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 19/119 (15%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA- 55
P P P+ P PP+ + P +PP P P A P P PPAA
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 56 -SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQST-GKGPPQSP 112
SP GP + G AP PP + AA +G ST P SP
Sbjct: 994 PSPKGGPATPSPKG---------APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Score = 36.6 bits (83), Expect = 0.13
Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 19/119 (15%)
Query: 4 PQPLQQPSQPQQPPPTQQ---AVARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA 55
P P + P PP+ + A P G + P LP P A P P PPAA
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 56 --SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
SP GP + G AP PP + G A +T P SP
Sbjct: 1087 PPSPKGGPATPSPKG---------APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Score = 36.6 bits (83), Expect = 0.13
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 9/121 (7%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P+ P PP+ + P G + P P P A PP A P P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 62 VAAAGSGL----RRGAEGILAPQPPPPQ--QHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
+ G GL +GA PP P+ P A A + KG P +P +
Sbjct: 1272 PSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 116 G 116
G
Sbjct: 1331 G 1331
Score = 36.2 bits (82), Expect = 0.17
Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 9/105 (8%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P P PPP A PP T P G P AT+ + G P S GP A
Sbjct: 1317 PPSPKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 66 GSGLRRGAEGILAPQP------PPPQQHQERPGAAAIGSARGQST 104
+ +G + P P P P+ P + + +T
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Score = 35.0 bits (79), Expect = 0.39
Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 24/125 (19%)
Query: 4 PQPLQQP------SQPQQ----PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP----- 48
P P Q P S P++ P P + P G +PP P P A P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG- 107
P PPAA P P + +GA A PP P+ G A S +G T
Sbjct: 963 PTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPK------GGPATPSPKGAPTPPAV 1014
Query: 108 PPQSP 112
P SP
Sbjct: 1015 TPPSP 1019
Score = 35.0 bits (79), Expect = 0.39
Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 18/120 (15%)
Query: 10 PSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
P+ P PP+ + P G PP P P A PP A +P P + G
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG- 1138
Query: 68 GLR----RGAEGILAPQP---------PPPQQHQERPGAAAIGSARGQST--GKGPPQSP 112
GL +GA A P PPP+ P A G +T KG P +P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Score = 35.0 bits (79), Expect = 0.39
Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 7/121 (5%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
P P P+ P P + + P G +P G L P T + PA ++P G
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
P + +G + A PP P++ A S + P +P V +
Sbjct: 1456 PATPSS----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 121 S 121
S
Sbjct: 1512 S 1512
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/127 (25%), Positives = 41/127 (32%), Gaps = 20/127 (15%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P+ P PP+ + P G + P P P A P A +P P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
Query: 62 VAAAGSGLRRGAEGILAPQPP-------------PPQQHQERPGAAAIGSARG---QSTG 105
+ G +G AP PP PP + P S +G S
Sbjct: 1249 PSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306
Query: 106 KGPPQSP 112
KG P P
Sbjct: 1307 KGAPTPP 1313
Score = 33.9 bits (76), Expect = 0.87
Identities = 61/258 (23%), Positives = 96/258 (37%), Gaps = 39/258 (15%)
Query: 796 PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL-Y 854
PG+ P Q + P ++ ++S A + P P P PQ
Sbjct: 2 PGEATETVPATE---QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58
Query: 855 ATVHQSYPHHA------TQLHAHQPQPAT---TPTGSQPQSQHAAPSPVQHQAGQAPHLG 905
+ +Q+ P + T L PQ ++ P G+ P++ P+ + A L
Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA-LA 117
Query: 906 SGQPQQNLYHPGALTGTPPSLPP------GPSAQSPQSSFP-----QPAAVYAIHHQQLP 954
P + P L GTP S P P + S+FP P +V +
Sbjct: 118 LASP---MIAP-TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV- 172
Query: 955 HGFTNMAHVTQAHVQTGITAAPP---PHP-GAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010
T A + + +T + P P+P G P PP ++ P H P ++ QSGV
Sbjct: 173 --ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASI-QSGV 227
Query: 1011 PALSASTPSPYPYIGHPQ 1028
+L +TP+ I PQ
Sbjct: 228 ASLPQTTPTTTLAIASPQ 245
Score = 32.0 bits (71), Expect = 3.3
Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 6/98 (6%)
Query: 16 PPPTQQAVARRPP-GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
PP + A PP G +PP P P + PP A P + P + G+
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 75 GILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P P + AA S +G GP +P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG-----GPAMTP 1386
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 104 bits (259), Expect = 5e-22
Identities = 208/813 (25%), Positives = 281/813 (34%), Gaps = 170/813 (20%)
Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
R GP R S + RP S R P N+SPGP S G G +R P Q+
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133
Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
LR G T LS+ + R SG T P PA+ R + P P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
++ P PP G SSAS T+ S G G PAS +S + T + +
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570
P AR + P ++ K L+ LR PP+
Sbjct: 254 RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630
+ P+ G L+S P+ +P S T++ P+ P P+ P P+
Sbjct: 285 V--TPPRKDAAPALGPLSSSPLATPSPSGTKA-------RPVPP------PDNAATPLPA 329
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
P P+A + + +P+A T P +TP S P +
Sbjct: 330 TLPPSP------------PLATPLPLAPPSPSAPPSLQTLP-----SPPATPPSQAPPSM 372
Query: 691 STPSIPVLTAGQSGLYSPQYISYIPQIHM-----GPAVQAPQMYPYPVSNS--------- 736
+TP + +P + IP I + P++QAP P P++ S
Sbjct: 373 TTPP----------MQAPPSLQTIPPIQVPHSLTSPSLQAP---PSPLALSSLQATTSLG 419
Query: 737 VPGQQGKY-------RGAKGSL-PPQRSDQHQPASAPPMMQAAAAAGPPL-----VAATP 783
P Q + R + SL P R P S P + A PPL A +P
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479
Query: 784 YSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG--SHPQAIVSSSTPQ 841
SS + +P Q A P A P + P L++ + + P ++ +
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQA--PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN 537
Query: 842 YPSAEQP---TPQALYATVH-QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQ 897
PS P T A T H ++ P A P P TTP P S A P P
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP-SSIATPPP---- 592
Query: 898 AGQAPHLGSGQPQQNLYHP--GALTGTPPSLPPG---PSAQSPQS-SFPQPAAVYAIHHQ 951
QAP + P Q L P L PP PP P Q+P S P + A
Sbjct: 593 --QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
Query: 952 QLPHGFTNMAHVTQAHVQTGITAAPPPHP------GAPHPPQVMLLHPPQSHGGPPQGAV 1005
Q P+ H+ QA +PPP P P P V P S P A
Sbjct: 651 QAPNALA--VHLLQA------PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 1006 PQSGVPALSASTP-----SPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQG 1060
P P+ AS P +P P P P Q P P +
Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA 762
Query: 1061 LAPGSVLCFPPSSLSCDP-AAPLPTASPALSDP 1092
P V PP+SL P A P P A PAL+ P
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
Score = 87.8 bits (216), Expect = 5e-17
Identities = 181/786 (23%), Positives = 246/786 (31%), Gaps = 96/786 (12%)
Query: 334 GSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPG 393
G G + P+ S PL R GP S+RG PR P H P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGP-------SARG--------TPRAPAHPSQPKPK 275
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYP---PRSP 450
R P R + L++PS + VPPP P P SP
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Query: 451 KSAAPAPISASCPE-PPIGSAVPTSSASIPVTS--SVSDPGVGSISPASPKISLAPTDVK 507
A P P++ P PP +P+ A+ P + S++ P + A P + P
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSLQTIPPIQV 391
Query: 508 ELSTKEPGRTLEPQELARIAGKVP---GLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL 564
S P P LA + + G Q + Q L S P ++
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451
Query: 565 DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT-----ESVSDKEDKPPLAPSGGTE 619
PP + P + P SP+SS +++S P AP
Sbjct: 452 PDSPPL---QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 620 GP--EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE---QVKKSTLNPNAKEFNPTKPLLS 674
P E P +PP L ++ +A Q + L E P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 675 VNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS 734
+ S T+P P T S+ + P A + L SP + +P + P P P ++
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPA-LASPP-LQGLPSPPLSPLATPPPQAPPXLA 626
Query: 735 NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
LPP ++ PAS PP+ A + A + P++P
Sbjct: 627 ----------------LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 795 FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854
P A P A P P P Q+ P + +S P PSA P
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP------ 723
Query: 855 ATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLY 914
P L A Q +P S P S A P P + P L + P Q
Sbjct: 724 -------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPP------RVPPLLAAPPLQVPP 770
Query: 915 HPGA------LTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHV 968
P A L PP PP A P + P P A + P M+ +
Sbjct: 771 SPPASLPMSPLAKPPPQAPPA-LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 969 QTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP-PQGAVPQSGVPALSASTPSPYPYIGHP 1027
Q A P P PP L P+ P P +V SG A P P P P
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV--SGPRLTLALAPGPPP----P 883
Query: 1028 QGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSS---LSCDPAAPLPT 1084
P P A R G PP +C PAA
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
Query: 1085 ASPALS 1090
+P L+
Sbjct: 944 PAPPLA 949
Score = 72.4 bits (176), Expect = 2e-12
Identities = 171/700 (24%), Positives = 238/700 (34%), Gaps = 157/700 (22%)
Query: 440 AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493
A R R+P P P + P PP+ A V ++ ++ P+ G +I
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553
++P+ PT S++ P P R + P +N
Sbjct: 72 ESAPRAG--PTRSAGTSSRNPAS--RPPASGR-GERAPPAKNTSPG-------------- 112
Query: 554 LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606
P SSP + P L ++ +E G T P S +S+ T +
Sbjct: 113 --PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170
Query: 607 EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
P +A G E P P PS PP EGP +KS +A E
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGP-----RKSV--SSASE 214
Query: 666 FNPTKPLLSVNKSTSTPTS---PGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
+ T+P + + S P R+ S+ + P+ + +SG P P
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----------PSARGTPR 264
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP----PL 778
A P P +G + PPQ + PP AA A GP PL
Sbjct: 265 APAHPSQPKP------------KGLQALRPPQVT--------PPRKDAAPALGPLSSSPL 304
Query: 779 VAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPML------QSNPRMLTSGSHPQ 832
ATP S P P A P PS P+ P+ + P + T S P
Sbjct: 305 --ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 833 AIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP--------ATTPTGSQP 884
S + P + P +L PH T P ATT GS
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 885 -QSQHA--APSPVQHQAG-QAPHLGSGQPQQN--LYHPGALTGTPP---SLPPGPSA-QS 934
Q+ H+ SP Q QA +P + P + L P +L +PP SL P S S
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 935 PQSSFP-QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP 993
P + P Q + A H Q P ++ + ++T + APP L P
Sbjct: 483 PLTIHPLQALSSLASHSPQAP-----LSSLIMPPLETQSSLAPPS-----------LQTP 526
Query: 994 PQSHGGPPQGAVPQSGVPAL-SASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGR 1052
P S PP +P P L +AS P P++ P P AP C +
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP----PCPAP-----------CPLQ- 570
Query: 1053 SHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDP 1092
AP S L PP A P P A PAL+ P
Sbjct: 571 ---------APPSPLTTPPPETPSSIATPPPQAPPALASP 601
Score = 46.2 bits (108), Expect = 2e-04
Identities = 43/134 (32%), Positives = 51/134 (38%), Gaps = 30/134 (22%)
Query: 4 PQPLQQPSQP--QQPPPTQQAVA----RRPPGGTSPPNGGLP----GPLATS-------- 45
P PLQ P P PP T ++A + PP SPP GLP PLAT
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
Query: 46 -----AAPPGPPAAASPCLGPVAAAGSGLRRG-----AEGILAPQPPPPQQHQERPGAAA 95
APP PP ASP L P+A + +P P PP Q P A+
Sbjct: 626 ALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Query: 96 IGSARGQSTGKGPP 109
S + PP
Sbjct: 684 PVSPSATPPSQAPP 697
Score = 37.7 bits (86), Expect = 0.060
Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 18/123 (14%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
PLQ P P PP P + PP+ + P + A+PP P+
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Query: 54 AASPCLGPVAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
A P P + A L+ A ++P PP Q P AA S PP
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPP 746
Query: 110 QSP 112
SP
Sbjct: 747 MSP 749
Score = 37.0 bits (84), Expect = 0.10
Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)
Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A
Sbjct: 843 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
S G G EG A PPP A + + + +GP F
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 950
Query: 115 EG 116
G
Sbjct: 951 RG 952
Score = 36.2 bits (82), Expect = 0.17
Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP-PGPPAAASPCLGP 61
KP+ LQ PQ PP + A P +SP P P T A P P P AA+P P
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPL--P 328
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP-QSP 112
S + P P P Q P A ++ + PP Q+P
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Score = 33.5 bits (75), Expect = 1.1
Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 24/113 (21%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCL 59
L PLQ P P PP + PP PP P P + A+PP P+A P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P A L+ + P PP S K PPQ+P
Sbjct: 757 VPPLLAAPPLQ------VPPSPP--------------ASLPMSPLAKPPPQAP 789
Score = 32.3 bits (72), Expect = 2.5
Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 22/130 (16%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVA---RRPPGGTSPPNGGLPGPLATS-----AAPP--GP 51
L PLQ P P PP + R PP +PP P P A+ A PP P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789
Query: 52 PAAASPCL-----GPVAAAGSG-LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
PA A+P L P + G A ++P PP P A + +A
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVP 843
Query: 106 KGPPQSPVFE 115
PP SP +
Sbjct: 844 PSPPASPTLQ 853
Score = 31.6 bits (70), Expect = 4.3
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
PPP + A P + P PLA AP G P P GP +A G EG
Sbjct: 926 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 980
Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
P+ PGA G + G S GK
Sbjct: 981 --------PESATPAPGALDPGPSPGTSGGK 1003
Score = 30.4 bits (67), Expect = 9.6
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 11 SQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 70
S P + P+ + R P + P GL PP AA P LGP++++
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATP 307
Query: 71 RGAEGILAPQPPP 83
+ P PPP
Sbjct: 308 SPSGTKARPVPPP 320
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 98.2 bits (243), Expect = 4e-20
Identities = 188/783 (24%), Positives = 268/783 (34%), Gaps = 136/783 (17%)
Query: 381 PRGPH--HLDNSSPGP-GSEARGINGGPSRMSPKAQRPLRGAKTL-----SSPSNRPSGE 432
P+G H + PGP EA+ + ++ P+ + PL L SP + P E
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEE 455
Query: 433 TSVPPPPAVGRMYPPRSPKSAAPAP----ISASCPEPPIGSAVPTSSASIPVTSSVSDPG 488
+ PPP R+ PP A+P P +S E P+ S S P SS P
Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP- 514
Query: 489 VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548
SP SP P+ E P E L+ P + EEL
Sbjct: 515 -LEESPLSPPEESPPSPALETPLSPPP---EASPLS------PPFEESPLSPPPEELPTS 564
Query: 549 GAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--------LTSEPMGSPVSSKT 600
+ S PE S PP +E P E L L+ P SP+S
Sbjct: 565 PPPEASRLSPPPEESPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
Query: 601 ES--VSDKEDKPPLAPSGGTEGPEQPPP--------PCPSQTGSPPVGLIKGEDKDEGPV 650
E+ +S + P++P E P PPP P S+ PP +E P
Sbjct: 622 EASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL-YSPQ 709
+ + S L+P E +PT P +P SP P S S+P+ + L PQ
Sbjct: 681 SPPPEASRLSP-PPEDSPTSP-----PPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQ 733
Query: 710 YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQH-QPASAPPMM 768
H+ P + P + P P + L PQ + H P P +
Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPRP--------------EEPHLSPQAEEPHLSPQPEEPCL 779
Query: 769 QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP-MAHYPSQPVFAPMLQS------- 820
A P ++ ++ P++ P +P ++ P +P +P +
Sbjct: 780 --CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837
Query: 821 -----NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP 875
+PR S P+ P P E+P + + P L +P
Sbjct: 838 EEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEPGQCPAPEELP-----LFPPPGEP 889
Query: 876 ATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP--QQNLYHPGALTGTPPSLPP----- 928
+ +P +P P+ + P SG+P L P L PP L P
Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---PPPLSPIITAA 946
Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGF----TNMAHVTQAHVQTGITAAP---PPHPG 981
P A SP P + P T ++ +A+ P PP PG
Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006
Query: 982 APHPPQVMLLH---PPQ-----SHGGPPQGAVP-QSGVPALSASTPSPYPYIGHPQGEQP 1032
+P P +L PPQ H PQ + P Q PAL S PSP IG
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGK------ 1060
Query: 1033 GQAPGFPGGADDRILCRVGRSHSRRRQ--GLAPG--SVLCFPPSSLSCDPAAPLPTASPA 1088
G +D+ L + + L P S L P LSC P P+ +PA
Sbjct: 1061 -----VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSC----PAPSPAPA 1111
Query: 1089 LSD 1091
L D
Sbjct: 1112 LDD 1114
Score = 55.1 bits (131), Expect = 4e-07
Identities = 141/594 (23%), Positives = 202/594 (34%), Gaps = 98/594 (16%)
Query: 422 LSSPSNRPSGETSVPPPP-AVGRMYPPRSP-----KSAAPAPISASCP---EPPIGSAVP 472
++ ++RP+ +PP P A+G P +P PA +S S +PP GS
Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152
Query: 473 TSSAS---------IPVTSSVSDP-GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
S +P DP G+ P P+ AP + G +P
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPM 2211
Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI----LKEEPK- 577
L A PG Q E S+P+ L P P + + E P
Sbjct: 2212 LG--ASSRPGAG------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 578 GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
G K + LL+ P G S K V KE+ +PS G PP SP
Sbjct: 2264 GGGKASEPLLSPPPFGE--SRKALEVK-KEELGASSPSYG--------PPNLGFVDSPSS 2312
Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
G G + + P V K+ L P A + P P L + P P P PS P
Sbjct: 2313 GTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLR-----PQEPPPAQALAPSPP- 2363
Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ---GKYRGAKGSLPPQ 754
++ P SY P PQ P ++P + + S P
Sbjct: 2364 ---SHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS-PQS 2417
Query: 755 RSDQHQPASAPPMMQAAAAAGPPLVAATP-YSSYIPYNPQQFPGQPAMMQPMA--HYPSQ 811
+S P + P+ A P TP + S PY+ P +P P A H P +
Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSP----VTPRFQSPDPYSRP--PSRPQSRDPFAPLHKPPR 2471
Query: 812 PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--------QPTPQALYATVHQSYPH 863
P P + L S ++ P P+ E QP P + + ++
Sbjct: 2472 PQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529
Query: 864 HATQLHAHQPQPATTPTGSQPQSQHAAPSP--VQHQAGQAPHLGSGQPQQNLYHPGALTG 921
+ + PQ P+ P Q P P + G P LG +PQ Y
Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG--KPQSTNYTVATGNF 2587
Query: 922 TPPSLPPGPSAQS-----------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVT 964
P P GPS+ S P S P PA ++ + L HG + + +T
Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY--LSHGASQRSGIT 2639
Score = 53.9 bits (128), Expect = 8e-07
Identities = 162/801 (20%), Positives = 262/801 (32%), Gaps = 142/801 (17%)
Query: 308 QYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIP-----LPQRVREGPRG 362
+YR + + + ++++HSAV + L G+ +P PQ G G
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653
Query: 363 GVRCSSSRGGRPGLSSLP-----------------------PRG---PHHLDNSSPGPGS 396
G+R + PG P P G P +L S GP S
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713
Query: 397 ---EARGINGGPSRMS-----------PKAQRPLRGAKTLSSPSNR-PSGETSVPPPPAV 441
+ R + RM + Q+ L G + + P +T+ P
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773
Query: 442 GRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
+ PP S + +S P+ P G P A + G++ P P +
Sbjct: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVL------QQQHPGALGPQGPHRQV 3827
Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS---- 557
T + LS+ + L Q + ++ Q +Q++ Q ++ LQ S
Sbjct: 3828 LMTQSRVLSSPQ----LAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883
Query: 558 -SSPENSLDPFPP-RILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPS 615
P+ S P + L+++ + ++++ + + + + + ++ + L
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943
Query: 616 GGTE----------GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
+ +Q Q +GL+ P +Q ++ L P
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-- 4001
Query: 666 FNPTKPLL--------------------SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL 705
P KPL +V+ + S+ + GP TH + + T +S
Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059
Query: 706 YSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV--------PGQQGK-----YRGAKGSLP 752
P + P + + Q P P +S+ PGQQ + + GS
Sbjct: 4060 TEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PS 810
S AS+ P + A P V+ + N P QP + +PM + P
Sbjct: 4118 QLGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLG-PQQPMLERPMQNNTGPQ 4171
Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
P P+LQS + G P + Q A+ P + L Q Q
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231
Query: 871 HQPQPAT-TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPG 929
Q Q TP +P +Q SP+Q G P LG PG TG L G
Sbjct: 4232 QQSQAVRQTPPYQEPGTQ---TSPLQGLLGCQPQLGG--------FPGPQTGPLQELGAG 4280
Query: 930 PSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA-PPPH 979
P Q P S+ P V+ P + + Q A PP H
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340
Query: 980 PGAPHPPQVMLLHPPQSHGGP 1000
PG P PQ L PP P
Sbjct: 4341 PGTP-KPQGPTLEPPPGRVSP 4360
Score = 53.1 bits (126), Expect = 1e-06
Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 108/505 (21%)
Query: 341 SLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPH--------------- 385
SL E +PLP+ + PR S R P LS P PH
Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPE 775
Query: 386 -----------HLDNSSPGP--GSEARGINGGPS----RMSPKAQRPLRGAKTLSSPSNR 428
HL + GP + ++ P +SP + P + S +
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Query: 429 PSGETSVPPPPAVGRM-----YPPRSPKSAAPAPISASCPEPPIGSAVP----TSSASIP 479
S E + P P + PP SP+ P CP P P S + +
Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
Query: 480 VTSSVSDPGVGSISPASPKISLAPTDVKELSTK-EPGRTLEPQELARIAGKVPGLQNEQK 538
++S+PG +SP ++ L+P+ LS + P L P I P
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP------ 949
Query: 539 RFQLEELRKFGAQFKLQPSSSPENSL--------------------DPFPPRILKEEPKG 578
L L + F + S PE+ L +P PP IL P
Sbjct: 950 --ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
Query: 579 KEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP--P 636
+L EP+ S + ++ PP S PP P SP P
Sbjct: 1008 PVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCS---------PPALPLSVPSPLSP 1057
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP--TKPLLSVNKSTSTPT-SPGPRTHSTP 693
+G + G DE + E + P P T PL S S P SP P
Sbjct: 1058 IGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
Query: 694 SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLP 752
+ TA G + AP P P PG + +G+ L
Sbjct: 1117 GLGEDTAPLDG------------------IDAPGSQPEP--GQTPGSLASELKGSPVLLD 1156
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPP 777
P+ P P + A G P
Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSP 1181
Score = 45.8 bits (107), Expect = 2e-04
Identities = 162/717 (22%), Positives = 240/717 (33%), Gaps = 148/717 (20%)
Query: 377 SSLPPRGPHHL---DNSSPGP---GSEARGINGGPSRMSPKAQRPLRGAKTLS-SPSNRP 429
+S P GP +L D+ S G G E + + + ++P+A + + L P P
Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP 2353
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489
+ P PP+ ++ P S P P+PP P S ++P S SDP
Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP----PPESCCALPPRSLPSDPF- 2408
Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
S PASP+ + S++ P L P+ L+ A + RFQ +
Sbjct: 2409 -SRVPASPQ--------SQSSSQSP---LTPRPLSAEAFCPSPVT---PRFQSPDPYS-- 2451
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD---GLLTSEPMGS---PVSSKTESV 603
+P S P+ S DPF P L + P+ + EV G L +G+ P +
Sbjct: 2452 -----RPPSRPQ-SRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
Query: 604 SDKEDKPPLAP---------SGGTEGPEQP--------------PPPCPSQTGSPPVGLI 640
+ K P +G G P PP P PP G+
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI- 2562
Query: 641 KGEDKDEGPVAEQVKKSTLNPNAKEFNPT-KPLLSVNKSTST--------PTSPGPRTHS 691
GP + + + F+P+ PL + ST P S P
Sbjct: 2563 -NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
Query: 692 TPSIPVLTAG---QSGLYSPQYISYIPQIHMG--------PAVQAPQMYPYPVS------ 734
S+P L+ G +SG+ SP P MG P Q P M +
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 735 ----------------NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPL 778
N++ ++ A G++ P S +P+S P + + P
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS--PAFEQLSRGQTPF 2739
Query: 779 VAATPYSSYIPYNPQQFPGQ---PAMM--QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
SS + P + G P P P + N R L GS QA
Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS--QA 2797
Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQ-SQHAAPS 892
+ YP + P Q Q AT + A P+ P+ + A S
Sbjct: 2798 FYQRAP--YPGS-LPLQQQQQQLWQQQQATAATSMRF--AMSARFPSTPGPELGRQALGS 2852
Query: 893 PVQHQAGQAPHLGSGQPQQNLYHPGALT--------GTPPSLPPGPSAQSPQSSFPQPAA 944
P+ + + P G G+P P G P P P PQ P+
Sbjct: 2853 PLAGISTRLP--GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYP 2908
Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-MLLHPPQSHGGP 1000
V H+ P G +A ++ PP P AP P++ LHP GP
Sbjct: 2909 VSEDPHRLAPEGLRGLA----------VSGLPPQKPSAPPAPELNNSLHPTPHTKGP 2955
Score = 43.9 bits (102), Expect = 8e-04
Identities = 88/358 (24%), Positives = 135/358 (37%), Gaps = 61/358 (17%)
Query: 361 RGGVRCSSSRGGRPGLSSLP---------PRGPHHLDNSSPGPGSEARGINGGPSRMSP- 410
+G + C GG PG + P P+GP L PG+ + G GP +P
Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPP 4310
Query: 411 --KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG 468
Q P R ++ L SPS++ E +PP P +PK P EPP G
Sbjct: 4311 PSSPQEPKRPSQ-LPSPSSQLPTEAQLPPT-------HPGTPKPQGPT------LEPPPG 4356
Query: 469 SAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528
P A+ + ++ G+G P P +LA T E S+ PG L ++ G
Sbjct: 4357 RVSP---AAAQLADTLFSKGLG---PWDPPDNLAETQKPEQSSLVPG------HLDQVNG 4404
Query: 529 KV--PGLQNEQKRFQLEELRKFGAQ-FKLQPSSSP------ENSLDPFPPR------ILK 573
+V Q K+ EE GAQ K + + P N L PR +L+
Sbjct: 4405 QVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQ 4464
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEG----PEQPPPPC 628
+ + K ++ SE + + ++ +S ++ E K PS + P P P
Sbjct: 4465 KLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524
Query: 629 PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPG 686
+ V K K++G A + L T+P ++ N S P G
Sbjct: 4525 VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSG 4582
Score = 39.3 bits (90), Expect = 0.021
Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 22/112 (19%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
+L + LQQ +Q PP Q+ PG + P GL G PGP G
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQE------PGTQTSPLQGLLGCQPQLGGFPGPQT------G 4272
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P+ G+G P+P P + PGA + G G PP SP
Sbjct: 4273 PLQELGAG----------PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
Score = 38.9 bits (89), Expect = 0.027
Identities = 94/390 (24%), Positives = 128/390 (32%), Gaps = 93/390 (23%)
Query: 721 PAVQAPQMY---PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
P AP ++ P + G + GS+P S PP + A + P
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176
Query: 778 LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS 837
A Y P P+ FP P P YPS P AP + P ML + S P
Sbjct: 2177 FGLAPAY----PLEPR-FPTAPPTYPP---YPS-PTGAP---AQPPMLGASSRP------ 2218
Query: 838 STPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQ 897
A QP + T P H QP+T +P+ PS
Sbjct: 2219 ------GAGQPGE---FHTTPPGTPRH---------QPSTPDPFLKPR----CPSLDNLA 2256
Query: 898 AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGF 957
++P +G G+ + P L P P +S ++ + + A +G
Sbjct: 2257 VPESPGVGGGKASE------------PLLSPPPFGESRKALEVKKEELGA---SSPSYGP 2301
Query: 958 TNMAHVTQAHVQT---GITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALS 1014
N+ V T G+ P AP P+ + P P G PQ PA
Sbjct: 2302 PNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQS----PGLGLRPQEPPPA-Q 2356
Query: 1015 ASTPSPYPYIGHPQGEQPG-------QAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVL 1067
A PSP HP +PG Q P P R Q P S
Sbjct: 2357 ALAPSPP---SHPDIFRPGSYTDPYAQPPLTP-----------------RPQPPPPESCC 2396
Query: 1068 CFPPSSLSCDPAAPLPTASPALSDPDCLLT 1097
PP SL DP + +P + + S LT
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
Score = 34.3 bits (77), Expect = 0.66
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 10/120 (8%)
Query: 2 LKPQPLQQPSQ--PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
L+ PL P + P PPP + SPP P P + P PP ASP
Sbjct: 489 LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLS 546
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS----PVFE 115
P S L E + PP + P + + +S PP++ P FE
Sbjct: 547 PPFEE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Score = 33.9 bits (76), Expect = 0.87
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 21/97 (21%)
Query: 2 LKPQ-PLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPG----PPAA 54
L+P+ P P+ P P PT +PP G +S P G PG T+ PPG P+
Sbjct: 2185 LEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240
Query: 55 ASPCLGP----------VAAAGSGLRRGAEGILAPQP 81
P L P + G G + +E +L+P P
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Score = 33.9 bits (76), Expect = 0.87
Identities = 85/391 (21%), Positives = 128/391 (32%), Gaps = 66/391 (16%)
Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG 620
+N++DP + E +G G P+ + ++ + E KP L+
Sbjct: 4026 QNTVDP---AVSSEATEGPSTHQGG-----PLAIGTTPESMATEPGEVKPSLSGDSQLLL 4077
Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQV---KKSTLNPNAKEFNPTKPLLSVNK 677
+ P P PS P + G+ + + + L + + P L
Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137
Query: 678 STSTPTSPGPRTHST--PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSN 735
S S PG T + P P+L PQ GP +Q+ Q P
Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIM 4191
Query: 736 SVPGQ-QGKYRGAKGSLP------PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYI 788
GQ + + +G P PQ+ Q Q +Q + A V TP
Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA-----VRQTP----- 4241
Query: 789 PYNPQQFPG-QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847
P Q PG Q + +Q + Q P Q+ P Q + + PQ P
Sbjct: 4242 ---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL--------QELGAGPRPQGPP-RL 4289
Query: 848 PTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907
P P +T P H T P ++P + SQ +PS Q P
Sbjct: 4290 PAPPGALSTGPVLGPVHPTP-------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPT--- 4339
Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSS 938
HPG P+L P P SP ++
Sbjct: 4340 -------HPGTPKPQGPTLEPPPGRVSPAAA 4363
Score = 33.5 bits (75), Expect = 1.1
Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P+P + P +P Q P ++ PPG P L G A S PG P SP
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG--EPSLSPLLGEPALS--EPGEP-PLSPLPEE 914
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ-----QHQERPGAAAIG------SARGQSTGKGPPQ 110
+ + SG + ++ P P PP P + +G A+G S + P
Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974
Query: 111 SPVFE 115
+P+ E
Sbjct: 975 APILE 979
Score = 32.0 bits (71), Expect = 3.3
Identities = 38/130 (29%), Positives = 46/130 (35%), Gaps = 28/130 (21%)
Query: 1 MLKPQPLQQPSQPQQPPP-------TQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53
+++PQP QPS Q PP QQ GG S G G ++S A P
Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQLGSGSSSEASSVPHL 4133
Query: 54 AASPCLGPVAAAGS-----------GLRRGAEGILAPQPPPP----QQHQERPGAA---A 95
A P + GS L R + PQPP P Q Q PG
Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193
Query: 96 IGSARGQSTG 105
+G R Q G
Sbjct: 4194 VGQLRAQLQG 4203
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPG-PLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
PP V + P G +P P P A PP P +P P+ A S G
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
Query: 75 GILAPQPPPPQQHQ 88
G PP +HQ
Sbjct: 2224 GEFHTTPPGTPRHQ 2237
Score = 31.2 bits (69), Expect = 5.6
Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 23/124 (18%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
K Q QQ Q QQ Q A+ ++ G PG A P P P
Sbjct: 3733 KLQQQQQQQQQQQHLLGQVAIQQQQQQG--------PGVQTNQALGPKPQGLMPPS---- 3780
Query: 63 AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
+G+L Q P PPQ Q G A + + Q G PQ P + +
Sbjct: 3781 ---------SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831
Query: 121 SRML 124
SR+L
Sbjct: 3832 SRVL 3835
Score = 31.2 bits (69), Expect = 5.6
Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 22/112 (19%)
Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893
I+S + P+ E PT SY ++ + L Q A P P APSP
Sbjct: 4875 ILSLLKQESPAPEPPT--------QHSYTYNVSNLDVRQLS-APPPEEPSPPPSPLAPSP 4925
Query: 894 VQHQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
+ P + L P PP P P A SP+S+ P+P A
Sbjct: 4926 ------------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Score = 30.4 bits (67), Expect = 9.6
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAA 64
+PL++ P PPP + ++ PP +SP + PL+ P PA +P L P
Sbjct: 487 RPLEE--SPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPE 541
Query: 65 AGSGLRRGAEGILAPQP------PPPQQHQERP 91
A E L+P P PPP+ + P
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574
Score = 30.4 bits (67), Expect = 9.6
Identities = 83/369 (22%), Positives = 113/369 (30%), Gaps = 80/369 (21%)
Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
QQ + + G + Q+ Q P +Q A GP P SS+ QQ QP
Sbjct: 3740 QQQQQQHLLGQVAIQQQQQQGPG-----VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794
Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRML-TSGSHPQAIVSSS----TPQYPSAEQPTPQALY 854
P+Q A + Q +P L G H Q +++ S +PQ Q
Sbjct: 3795 PQGPQGMLGPAQ--VAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852
Query: 855 ATVHQ----------------SYPHHATQLHAHQPQPATTPTGS--------QPQSQHAA 890
T Q S+ + H+ QP+ + P GS Q Q Q
Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912
Query: 891 PSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH 950
Q Q Q L Q QQ L Q Q Q +
Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ--QQQQQLQQQQQQQQQQFQQQQ 3970
Query: 951 QQLPHGFTNMAHV---------TQAHVQTGITAAPPPH---PGAPHPPQVM--------- 989
QQ G N + Q + G+ A P H PGA P ++
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030
Query: 990 ------LLHPPQSHGGPPQ--GAVPQSGV-------PALSAST------PSPYPYIGHPQ 1028
P +H G P G P+S P+LS + P P P Q
Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
Query: 1029 GEQPGQAPG 1037
+ P + PG
Sbjct: 4091 LQPPLRLPG 4099
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 95.1 bits (235), Expect = 3e-19
Identities = 181/766 (23%), Positives = 255/766 (33%), Gaps = 115/766 (15%)
Query: 357 REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGING-GPSRMSPKAQRP 415
R+ + G + PGL L PR P P + R + G P A+R
Sbjct: 5 RDKAKAGAAARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 416 LRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474
G + P + P +G T PPA GR K+ +P P+S+ P G+ P
Sbjct: 63 -GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRP-- 117
Query: 475 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-IAGKVPGL 533
G + +IS T + +T+ P R+ R +G PG
Sbjct: 118 ---------------GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
+ R G + L P S P PP E P+ T+EP
Sbjct: 163 PSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEHSTTEP-- 211
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652
SP + + S +P + P P PS G+P + K +G +
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQ 269
Query: 653 QVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPG-----PRTHSTPSIPVLTAGQS--G 704
++ + P K+ P PL S +T +P++P P + PS P Q+
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 705 LYSPQYI---SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQP 761
L SP S++P + P P P ++ LPP ++ P
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----------------LPPLQAPPSPP 373
Query: 762 ASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
AS PP+ A + A + P++P P A P A P P P Q+
Sbjct: 374 AS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432
Query: 822 PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881
P + +S P PSA P PQA P A L +P P P
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQLAKPPPQAPPAL 484
Query: 882 SQPQSQHAAPSPVQHQAGQAPHLGSGQ-PQQNLYHPGALTGTPPSLPP---GPSAQSPQS 937
+ P Q A PSP GQAP S P L P PP PP P Q P
Sbjct: 485 ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATP------PPQAPPVLAAPLLQVP-- 535
Query: 938 SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP----------------- 980
P P A + + P V+ + + PPP P
Sbjct: 536 --PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593
Query: 981 -GAPHPPQVMLLHPPQSHGG-----PPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQ 1034
A P+ + + GG PP + A S P + G P P
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653
Query: 1035 APGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAA 1080
PG AD LC + + APG++ P S AA
Sbjct: 654 PATGPGSADG--LCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 697
Score = 39.7 bits (91), Expect = 0.016
Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
PLQ P P PP P + PP+ + P + A+PP P+
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
A P P + A L+ + P PP PP P A +A K PP
Sbjct: 425 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Query: 110 QSP 112
Q+P
Sbjct: 479 QAP 481
Score = 38.5 bits (88), Expect = 0.035
Identities = 124/519 (23%), Positives = 166/519 (31%), Gaps = 171/519 (32%)
Query: 585 GLLTSEPMGSP--------VSSKTESVSDKEDKPPLAPSGGTEG----PEQPPPPCPSQT 632
GLLT P GSP + + + + PLA G G PE P P++T
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82
Query: 633 GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST 692
PP +GE P AK +P P+ S +++ T T PGP
Sbjct: 83 SRPPASG-RGERA---------------PPAKNTSPG-PVSSPGRASGT-TRPGP----- 119
Query: 693 PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLP 752
GQ GL IS + G A +AP+ G R G P
Sbjct: 120 -------LGQKGLR----ISAEETVARGKATEAPKRSALSA--------GARRDTSGPTP 160
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQP 812
S P M + + AAG + P S
Sbjct: 161 GTPS--------PAMARRSRAAGTEVGLPRPAPS-------------------------- 186
Query: 813 VFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYA-TVHQSYPHHATQLHAH 871
+ PR T G P+ VSS++ S +P+P A + A++ +
Sbjct: 187 -------ARPRPPTEG--PRKSVSSASEH--STTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPS 931
P ++P S P ++ +P + L + +P Q TPP P
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV---------TPPRKDAAP- 285
Query: 932 AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLL 991
A P SS P + + PP P AP P L
Sbjct: 286 ALGPLSSSPLATP----------------------------SPSAPPSPSAP-PSLQTLP 316
Query: 992 HPPQSHGGPPQGAVPQSGVPALSAS---TPSPYPYIGHPQGEQPGQAPGFPGGADDRILC 1048
PP + PP A G P L A+ PSP P P P QAP P A
Sbjct: 317 SPPAT---PPSQATTSLGSPTLQATHSFLPSP-PL--SPLATPPPQAP--PALA------ 362
Query: 1049 RVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASP 1087
L P L PPS + P +PL T SP
Sbjct: 363 ------------LPP---LQAPPSPPASPPLSPLATPSP 386
Score = 38.1 bits (87), Expect = 0.046
Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 22/110 (20%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATS-AAPPGPPAAASPCLGPVAAAG 66
P+ P QP P + A RPP T P P GPL++S A P P A SP P
Sbjct: 257 PAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----- 310
Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPPQSPV 113
+ + +P PP Q ++GS Q+T PP SP+
Sbjct: 311 -----SLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPL 350
Score = 37.0 bits (84), Expect = 0.10
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVAR---------RPPGGTSPPNGGLPGPLATSAAPPG-PP 52
KP+ LQ PQ PP + A P ++PP+ P L T +PP PP
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323
Query: 53 AAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQS 111
+ A+ LG + + + PPPQ P A A+ + S PP S
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APPALALPPLQAPPSPPASPPLS 379
Query: 112 PV 113
P+
Sbjct: 380 PL 381
Score = 37.0 bits (84), Expect = 0.10
Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)
Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A
Sbjct: 535 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591
Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
S G G EG A PPP A + + + +GP F
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 642
Query: 115 EG 116
G
Sbjct: 643 RG 644
Score = 33.9 bits (76), Expect = 0.87
Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
P PL P PP Q PP +PP LP P A+ SA+ P P A
Sbjct: 463 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
P P A L+ + P PP P Q R P + G + G
Sbjct: 518 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 108 PPQSP 112
PP P
Sbjct: 572 PPPPP 576
Score = 33.1 bits (74), Expect = 1.5
Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 34/143 (23%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQ----------AVARRP--------PGGTSPPNGGLPGPL 42
+L P+P P P+ PPP AV R+P G T P + GP
Sbjct: 24 LLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 43 ATSAAPPG-----PPAAASPCLGPVAAAG--SGLRR----GAEG--ILAPQPPPPQQHQE 89
TS P P A + GPV++ G SG R G +G I A + + E
Sbjct: 81 RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140
Query: 90 RPGAAAIGSARGQSTGKGPPQSP 112
P +A+ + + T P +P
Sbjct: 141 APKRSALSAGARRDTSGPTPGTP 163
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
P P PP Q PP PP L P + A+PP P A P A A L
Sbjct: 346 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
+ +P P PP Q P A+ S + PP
Sbjct: 398 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Score = 31.6 bits (70), Expect = 4.3
Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
P+Q P P PP + P +PP+ P PL +PP P P+A P P
Sbjct: 408 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 463
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
A L+ LA PP P A+ S G+ P P SP+
Sbjct: 464 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Score = 31.6 bits (70), Expect = 4.3
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
PPP + A P + P PLA AP G P P GP +A G EG
Sbjct: 618 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 672
Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
P+ PGA G + G S GK
Sbjct: 673 --------PESATPAPGALDPGPSPGTSGGK 695
Score = 30.4 bits (67), Expect = 9.6
Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 21/126 (16%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP--------PAAASP 57
P P++ +PP + + P TSP PG A+ PGP A +
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETV 133
Query: 58 CLGPV------AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIG------SARGQSTG 105
G +A +G RR G P P + R +G SAR +
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 106 KGPPQS 111
+GP +S
Sbjct: 194 EGPRKS 199
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 89.7 bits (221), Expect = 1e-17
Identities = 186/777 (23%), Positives = 253/777 (32%), Gaps = 169/777 (21%)
Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
R GP R S + RP S R P N+SPGP S G G +R P Q+
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133
Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
LR G T LS+ + R SG T P PA+ R + P P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
++ P PP G SSAS T+ S G G PAS +S + T + +
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570
P AR + P ++ K L+ LR PP+
Sbjct: 254 RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630
+ P+ G L+S P+ +P +PS + Q PP P+
Sbjct: 285 VTP--PRKDAAPALGPLSSSPLATP-----------------SPSAALQS--QAPPTLPA 323
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
S + +A + + +P+A T P S P +P +
Sbjct: 324 TPHSSSLTC---------QLATPLPLAPPSPSAPPSLQTLP--------SPPATPPSQAT 366
Query: 691 STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750
++ P L A S L SP + P P P ++
Sbjct: 367 TSLGSPTLQATHSFLPSPP---------LSPLATPPPQAPPALA---------------- 401
Query: 751 LPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPS 810
LPP ++ PAS PP+ A + A + P++P P A P A P
Sbjct: 402 LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
P P Q+ P + +S P PSA P PQA P A L
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQL 512
Query: 871 HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ-PQQNLYHPGALTGTPPSLPP- 928
+P P P + P Q A PSP GQAP S P L P PP PP
Sbjct: 513 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATP------PPQAPPV 565
Query: 929 --GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP------ 980
P Q P P P A + + P V+ + + PPP P
Sbjct: 566 LAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 981 ------------GAPHPPQVMLLHPPQSHGG-----PPQGAVPQSGVPALSASTPSPYPY 1023
A P+ + + GG PP + A S P +
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 1024 IGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAA 1080
G P P PG AD LC + + APG++ P S AA
Sbjct: 682 RGAPGAPLPWPPATGPGSADG--LCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 736
Score = 43.5 bits (101), Expect = 0.001
Identities = 84/334 (25%), Positives = 115/334 (34%), Gaps = 57/334 (17%)
Query: 769 QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNP-RMLTS 827
++A AGP A T SS P + G+ P + PV +P S R
Sbjct: 72 ESAPRAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 828 GSHPQAIVSSSTPQYPSA-EQPTPQALYATVHQ--SYPHHATQLHAHQPQPATTPTGSQP 884
G I + T A E P AL A + S P T P PA
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT------PSPAMARRSRAA 183
Query: 885 QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
++ P P + P G P++++ + T PS P S +PA+
Sbjct: 184 GTEVGLPRPAPSARPRPPTEG---PRKSVSSASEHSTTEPS-PAARRRPSAGGGLQRPAS 239
Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGA 1004
+ L T ++ ++ T P HP P P + L PPQ P + A
Sbjct: 240 ------RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDA 292
Query: 1005 VPQSGVPALSA-STPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAP 1063
P G + S +TPSP + Q + P P P HS
Sbjct: 293 APALGPLSSSPLATPSPSAAL---QSQAPPTLPATP--------------HS-------- 327
Query: 1064 GSVLCFPPSSLSCDPAAPLPTASPALSDPDCLLT 1097
SSL+C A PLP A P+ S P L T
Sbjct: 328 --------SSLTCQLATPLPLAPPSPSAPPSLQT 353
Score = 39.7 bits (91), Expect = 0.016
Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
PLQ P P PP P + PP+ + P + A+PP P+
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
A P P + A L+ + P PP PP P A +A K PP
Sbjct: 464 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 110 QSP 112
Q+P
Sbjct: 518 QAP 520
Score = 37.0 bits (84), Expect = 0.10
Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)
Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A
Sbjct: 574 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
S G G EG A PPP A + + + +GP F
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 681
Query: 115 EG 116
G
Sbjct: 682 RG 683
Score = 36.2 bits (82), Expect = 0.17
Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 20/124 (16%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAA-------- 54
KP+ LQ PQ PP + A P +SP P S APP PA
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332
Query: 55 --ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPP 109
A+P P+A + + +P PP Q ++GS Q+T PP
Sbjct: 333 QLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPP 385
Query: 110 QSPV 113
SP+
Sbjct: 386 LSPL 389
Score = 33.9 bits (76), Expect = 0.87
Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
P PL P PP Q PP +PP LP P A+ SA+ P P A
Sbjct: 502 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
P P A L+ + P PP P Q R P + G + G
Sbjct: 557 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 108 PPQSP 112
PP P
Sbjct: 611 PPPPP 615
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
P P PP Q PP PP L P + A+PP P A P A A L
Sbjct: 385 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
+ +P P PP Q P A+ S + PP
Sbjct: 437 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Score = 31.6 bits (70), Expect = 4.3
Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
P+Q P P PP + P +PP+ P PL +PP P P+A P P
Sbjct: 447 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 502
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
A L+ LA PP P A+ S G+ P P SP+
Sbjct: 503 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Score = 31.6 bits (70), Expect = 4.3
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
PPP + A P + P PLA AP G P P GP +A G EG
Sbjct: 657 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 711
Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
P+ PGA G + G S GK
Sbjct: 712 --------PESATPAPGALDPGPSPGTSGGK 734
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 82.4 bits (202), Expect = 2e-15
Identities = 181/756 (23%), Positives = 249/756 (32%), Gaps = 109/756 (14%)
Query: 391 SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439
+PGP E R GG S S KA++ + AK S+P G +
Sbjct: 20 APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79
Query: 440 AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495
P+ K+ P P S S + G ++ +S P D S SP+
Sbjct: 80 ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136
Query: 496 SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
SP +D ++ P R P L + + P Q E
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 556 PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611
P P + + PP P+ G+L+ PMG SV K+ PP
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 612 LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
P S + G PP P T PVG G + P T N P
Sbjct: 257 TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305
Query: 671 PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727
L +N ++++P G P PS + G GL P GP + +P
Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357
Query: 728 MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
P P S+S P PP R +S+ +++++ + P S
Sbjct: 358 SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404
Query: 788 IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836
+P P FP ++ P PS P A Q P R+L S +HP
Sbjct: 405 LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464
Query: 837 SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895
S+ Q S P P + + HQ Q Q Q S P A P P++
Sbjct: 465 STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
Query: 896 ------HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ--PAAVYA 947
H +P LGS +P Y PG P LPP S S + P P + +
Sbjct: 522 GSSHHAHPYAMSPSLGSLRP----YPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSS 572
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP------QVMLLHPPQSHGGPP 1001
G +H + + G AP P P P ++ S G
Sbjct: 573 NSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK 629
Query: 1002 QGAVPQSGVPALSASTPSPYPY-IGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQG 1060
+ P G P PSP Y P G +PG P F G G S
Sbjct: 630 TASPP--GPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYR---GTSPPAGPGT 684
Query: 1061 LAPGSVLC----FPPSSLSCDPAAPLPTASPALSDP 1092
PGS PP+ S P+ P P A+PA P
Sbjct: 685 FKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Score = 65.1 bits (157), Expect = 4e-10
Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
GG G+ S PP GP G S G NGG P + + +P +P
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275
Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P VG P +P A ++ + P PP + +SAS P + PG
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327
Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
P+ + + K P P L + P RF A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383
Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
SSS +S PFP L S P P P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414
Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
P + S + P+ P PSQ G PP P + S +P
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459
Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
P P + P S H Q Q Q H P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
+P+P+ Y SL R PA PP A GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
+ SS P P P+ A YP PV P + ++ L S A V+SS
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625
Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
Y +A P P P + + + TP G +P SP + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668
Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
P + G+ P + PG+ T P LPP GPS S P P A A P
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722
Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
T + +T + PP +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754
Score = 60.1 bits (144), Expect = 1e-08
Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)
Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
GP+GG SS G G PP P + +S +P + GG
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
P+ P A RPL A L SP G +PP P G
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
P SP S PA S+S P PP+ P +SS S S S +S S +P
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
+ P P L+ + N+ ++ L + P P L
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
PFPP T+ P PVS+ + + ++ +
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
G PPPP G+ P L G P A +L P P P
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546
Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
P S + + P+ P +++ + S SY P H P+ Q PQ PYP
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601
Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
+S + G K + PP + A +P + A G
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
P TP + P P F PG P + P P+ P P L P SG
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
A P +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744
Score = 40.8 bits (94), Expect = 0.007
Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)
Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
P P R G + ++ G +PG P +P PG GP P
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687
Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
+ P G L P PSG S+PPPPA PP S +P P
Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
+ S PP VP+ ++ + D G S A + P + +L+ K
Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801
Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
E ++ AR + + +K + E+ R+ KL Q +P SL P P R
Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
E + T P P + ++S+ +P + G P P P
Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913
Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
G L + P A + ++ + ++ KP V S P PGP
Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966
Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
P H G A+Q P ++P+P S+ P ++ +
Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003
Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
A G +L P S + A+ + AA G +A + P++ Q +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063
Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
Q A + + P++ L SGSH I YP+ P P +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106
Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
P H ++ HQ A P P S +AP HQ QA H S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152
Score = 40.4 bits (93), Expect = 0.009
Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)
Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
HH ++ P PG+ + GG S + P + +L S P G +PPP
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552
Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
+ S A P P+S+S S+ TS S P + G P +
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
T LST T+ PG KR K +P S
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661
Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
PP P G TS P G PP PSG P
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707
Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
PPPP +G P + + P E + P A+ +P ++ V S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
Score = 37.0 bits (84), Expect = 0.10
Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
+P PP + PPG GTSPP G PGPL S P PP A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
P GP +A + AE P+ P P P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
P P Q PS P PPPT +V+ +PP T P LP S PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446
Score = 35.8 bits (81), Expect = 0.23
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)
Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
QQ Q QQ QQ + PP G P PL ++ P A SP LG
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538
Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
L P PP P H P + S G + GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569
Score = 33.9 bits (76), Expect = 0.87
Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)
Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
P PL PS QP P Q + P +P P TS PP A P P
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218
Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
G G G+L+ P P+ G A S G + GK PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260
Score = 33.1 bits (74), Expect = 1.5
Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)
Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
Q PPPT +PP P+ P PP A P + P LR
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
A PP Q PG A GQ G PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 82.4 bits (202), Expect = 2e-15
Identities = 181/756 (23%), Positives = 249/756 (32%), Gaps = 109/756 (14%)
Query: 391 SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439
+PGP E R GG S S KA++ + AK S+P G +
Sbjct: 20 APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79
Query: 440 AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495
P+ K+ P P S S + G ++ +S P D S SP+
Sbjct: 80 ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136
Query: 496 SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
SP +D ++ P R P L + + P Q E
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 556 PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611
P P + + PP P+ G+L+ PMG SV K+ PP
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 612 LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
P S + G PP P T PVG G + P T N P
Sbjct: 257 TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305
Query: 671 PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727
L +N ++++P G P PS + G GL P GP + +P
Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357
Query: 728 MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
P P S+S P PP R +S+ +++++ + P S
Sbjct: 358 SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404
Query: 788 IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836
+P P FP ++ P PS P A Q P R+L S +HP
Sbjct: 405 LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464
Query: 837 SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895
S+ Q S P P + + HQ Q Q Q S P A P P++
Sbjct: 465 STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
Query: 896 ------HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ--PAAVYA 947
H +P LGS +P Y PG P LPP S S + P P + +
Sbjct: 522 GSSHHAHPYAMSPSLGSLRP----YPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSS 572
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP------QVMLLHPPQSHGGPP 1001
G +H + + G AP P P P ++ S G
Sbjct: 573 NSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK 629
Query: 1002 QGAVPQSGVPALSASTPSPYPY-IGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQG 1060
+ P G P PSP Y P G +PG P F G G S
Sbjct: 630 TASPP--GPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYR---GTSPPAGPGT 684
Query: 1061 LAPGSVLC----FPPSSLSCDPAAPLPTASPALSDP 1092
PGS PP+ S P+ P P A+PA P
Sbjct: 685 FKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Score = 65.1 bits (157), Expect = 4e-10
Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
GG G+ S PP GP G S G NGG P + + +P +P
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275
Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P VG P +P A ++ + P PP + +SAS P + PG
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327
Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
P+ + + K P P L + P RF A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383
Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
SSS +S PFP L S P P P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414
Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
P + S + P+ P PSQ G PP P + S +P
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459
Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
P P + P S H Q Q Q H P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
+P+P+ Y SL R PA PP A GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
+ SS P P P+ A YP PV P + ++ L S A V+SS
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625
Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
Y +A P P P + + + TP G +P SP + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668
Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
P + G+ P + PG+ T P LPP GPS S P P A A P
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722
Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
T + +T + PP +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754
Score = 60.1 bits (144), Expect = 1e-08
Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)
Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
GP+GG SS G G PP P + +S +P + GG
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
P+ P A RPL A L SP G +PP P G
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
P SP S PA S+S P PP+ P +SS S S S +S S +P
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
+ P P L+ + N+ ++ L + P P L
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
PFPP T+ P PVS+ + + ++ +
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
G PPPP G+ P L G P A +L P P P
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546
Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
P S + + P+ P +++ + S SY P H P+ Q PQ PYP
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601
Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
+S + G K + PP + A +P + A G
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
P TP + P P F PG P + P P+ P P L P SG
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
A P +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744
Score = 40.8 bits (94), Expect = 0.007
Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)
Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
P P R G + ++ G +PG P +P PG GP P
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687
Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
+ P G L P PSG S+PPPPA PP S +P P
Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
+ S PP VP+ ++ + D G S A + P + +L+ K
Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801
Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
E ++ AR + + +K + E+ R+ KL Q +P SL P P R
Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
E + T P P + ++S+ +P + G P P P
Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913
Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
G L + P A + ++ + ++ KP V S P PGP
Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966
Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
P H G A+Q P ++P+P S+ P ++ +
Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003
Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
A G +L P S + A+ + AA G +A + P++ Q +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063
Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
Q A + + P++ L SGSH I YP+ P P +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106
Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
P H ++ HQ A P P S +AP HQ QA H S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152
Score = 40.4 bits (93), Expect = 0.009
Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)
Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
HH ++ P PG+ + GG S + P + +L S P G +PPP
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552
Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
+ S A P P+S+S S+ TS S P + G P +
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
T LST T+ PG KR K +P S
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661
Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
PP P G TS P G PP PSG P
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707
Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
PPPP +G P + + P E + P A+ +P ++ V S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
Score = 37.0 bits (84), Expect = 0.10
Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
+P PP + PPG GTSPP G PGPL S P PP A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
P GP +A + AE P+ P P P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
P P Q PS P PPPT +V+ +PP T P LP S PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446
Score = 35.8 bits (81), Expect = 0.23
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)
Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
QQ Q QQ QQ + PP G P PL ++ P A SP LG
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538
Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
L P PP P H P + S G + GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569
Score = 33.9 bits (76), Expect = 0.87
Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)
Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
P PL PS QP P Q + P +P P TS PP A P P
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218
Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
G G G+L+ P P+ G A S G + GK PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260
Score = 33.1 bits (74), Expect = 1.5
Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)
Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
Q PPPT +PP P+ P PP A P + P LR
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
A PP Q PG A GQ G PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 81.6 bits (200), Expect = 4e-15
Identities = 142/534 (26%), Positives = 191/534 (35%), Gaps = 89/534 (16%)
Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
E +DP PP + K ++E DGL M + S + S + K P +P G T
Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
+ S SP D AE VKKS + +P K +
Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
++ T RT S P+ P G+S G P+ I + P
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713
Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
++ +PQ +S QQ + +L P+SAPP GP
Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766
Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P
Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
+PS P + S P HA LH P P + P QH P P
Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876
Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
Q GQAP LG+ P +L P + + PP LPP P A +P
Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935
Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
P P A H P F+ A++ +++ HP + HPP + L+ PQ
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993
Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGG 1041
S P A P P L+ S P P HP QP Q P PGG
Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Score = 73.2 bits (178), Expect = 1e-12
Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
SG+ S+ + G M RS + PA S PI + +S + P +S S D
Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
++ ++ K+ + + + ++ + E A + K+ + +E+ +
Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
P+S E + R + +E K++D TS + SP ++++S S
Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
+ + PP AP+G T P PP P PS T PP G P
Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788
Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
A + L+P +P PL + S P++P +H+ P
Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844
Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
P+ G G +S PQ PQ G A YP+ S +P
Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902
Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
Q + + LP ++ +H P + P + A
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962
Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
PP A P SS ++P P + P + PS P P L QS SHP
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
+ PQ P A+ P P + P +T PA T +QP AA
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
S G + L + Q ++ +PP P PS + P A+ A ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135
Query: 952 QLPHGFTNMA 961
L G+ + A
Sbjct: 1136 HLDRGYNSCA 1145
Score = 47.0 bits (110), Expect = 1e-04
Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
P L L HH ++ P P PS SP L ++ L P S+ P+G
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024
Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
V P PP + P P P P S PP G P +SA P + + + G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080
Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
G S P + + + + E P R+ P+ + AR +
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
N R L + G++ + + E + + +E + KEKE + E
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200
Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S S E + P G P PPP P +G
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247
Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
P P L + P SP R H P+ P+L G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
LY+ + P ++ ++ + + ++ + R G + P D PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340
Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
+ P + +A PP P++S+ P NP ++ ++P YP +
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
+ LTS + + + TP H + H + LH HQ P
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444
Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
+ P A P + + G P+ GQP + L HP T P L
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504
Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
PP +A Q+ Q A + + QQ HG +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
L PQ PS P QPP Q+ PP + PP G G P P+
Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
+TS P GP +A P AA+G + G+ P P Q +E A+
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100
Query: 99 ARGQSTGKGPPQSP 112
A + PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
G P SS PP P +PGP A + P +G+ T S N+P
Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789
Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
T+ P + + ++P R P +P P P PP+ T SA P S + P
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
+ P P A ++ +P L PQ G+ P + + L+
Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900
Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
+Q LQ P E L P P P+ K P ++
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960
Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
L P P+SS + PPL P G T+ PPPP
Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
PP GL + + P A+ P PT P STSTP + GP T
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065
Query: 691 STPSIPVLTAGQSG 704
+ P P A SG
Sbjct: 1066 AQP--PCSGAAASG 1077
Score = 38.9 bits (89), Expect = 0.027
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838
Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
S P+ G G G L P PPQ P A+ + G S P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896
Score = 37.0 bits (84), Expect = 0.10
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P Q ++ QQ + + P P G P P S+APPG P +P P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772
Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
G ++ PQ P P H A A+ R S P SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
QP Q P A + PPG P G P P AT+ P G P A+ P A
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795
Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
+ A P P PP P + + GQ + Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Score = 32.3 bits (72), Expect = 2.5
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P PL P + PP T P PP+ P P + +A P PPA L P
Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
+++ + A PPP Q Q Q P + A QS PP
Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 81.6 bits (200), Expect = 4e-15
Identities = 142/534 (26%), Positives = 191/534 (35%), Gaps = 89/534 (16%)
Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
E +DP PP + K ++E DGL M + S + S + K P +P G T
Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
+ S SP D AE VKKS + +P K +
Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
++ T RT S P+ P G+S G P+ I + P
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713
Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
++ +PQ +S QQ + +L P+SAPP GP
Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766
Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P
Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
+PS P + S P HA LH P P + P QH P P
Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876
Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
Q GQAP LG+ P +L P + + PP LPP P A +P
Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935
Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
P P A H P F+ A++ +++ HP + HPP + L+ PQ
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993
Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGG 1041
S P A P P L+ S P P HP QP Q P PGG
Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Score = 73.2 bits (178), Expect = 1e-12
Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
SG+ S+ + G M RS + PA S PI + +S + P +S S D
Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
++ ++ K+ + + + ++ + E A + K+ + +E+ +
Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
P+S E + R + +E K++D TS + SP ++++S S
Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
+ + PP AP+G T P PP P PS T PP G P
Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788
Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
A + L+P +P PL + S P++P +H+ P
Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844
Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
P+ G G +S PQ PQ G A YP+ S +P
Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902
Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
Q + + LP ++ +H P + P + A
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962
Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
PP A P SS ++P P + P + PS P P L QS SHP
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
+ PQ P A+ P P + P +T PA T +QP AA
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
S G + L + Q ++ +PP P PS + P A+ A ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135
Query: 952 QLPHGFTNMA 961
L G+ + A
Sbjct: 1136 HLDRGYNSCA 1145
Score = 47.0 bits (110), Expect = 1e-04
Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
P L L HH ++ P P PS SP L ++ L P S+ P+G
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024
Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
V P PP + P P P P S PP G P +SA P + + + G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080
Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
G S P + + + + E P R+ P+ + AR +
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
N R L + G++ + + E + + +E + KEKE + E
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200
Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S S E + P G P PPP P +G
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247
Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
P P L + P SP R H P+ P+L G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
LY+ + P ++ ++ + + ++ + R G + P D PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340
Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
+ P + +A PP P++S+ P NP ++ ++P YP +
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
+ LTS + + + TP H + H + LH HQ P
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444
Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
+ P A P + + G P+ GQP + L HP T P L
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504
Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
PP +A Q+ Q A + + QQ HG +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
L PQ PS P QPP Q+ PP + PP G G P P+
Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
+TS P GP +A P AA+G + G+ P P Q +E A+
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100
Query: 99 ARGQSTGKGPPQSP 112
A + PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
G P SS PP P +PGP A + P +G+ T S N+P
Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789
Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
T+ P + + ++P R P +P P P PP+ T SA P S + P
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
+ P P A ++ +P L PQ G+ P + + L+
Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900
Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
+Q LQ P E L P P P+ K P ++
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960
Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
L P P+SS + PPL P G T+ PPPP
Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
PP GL + + P A+ P PT P STSTP + GP T
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065
Query: 691 STPSIPVLTAGQSG 704
+ P P A SG
Sbjct: 1066 AQP--PCSGAAASG 1077
Score = 38.9 bits (89), Expect = 0.027
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838
Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
S P+ G G G L P PPQ P A+ + G S P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896
Score = 37.0 bits (84), Expect = 0.10
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P Q ++ QQ + + P P G P P S+APPG P +P P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772
Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
G ++ PQ P P H A A+ R S P SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
QP Q P A + PPG P G P P AT+ P G P A+ P A
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795
Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
+ A P P PP P + + GQ + Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Score = 32.3 bits (72), Expect = 2.5
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P PL P + PP T P PP+ P P + +A P PPA L P
Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
+++ + A PPP Q Q Q P + A QS PP
Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 80.1 bits (196), Expect = 1e-14
Identities = 137/518 (26%), Positives = 184/518 (35%), Gaps = 84/518 (16%)
Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP 635
K ++E DGL M + S + S + K P +P G T + S SP
Sbjct: 3 KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRS--SGRNSP 60
Query: 636 PVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST--- 692
D AE VKKS + +P K + ++ T RT S
Sbjct: 61 SAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 116
Query: 693 ------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737
P+ P G+S G P+ I + P++ +PQ +S
Sbjct: 117 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSPSIPSPQDNESDSDSSA 175
Query: 738 PGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP- 796
QQ + +L P+SAPP GP TP ++ +P PQ P
Sbjct: 176 --QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP--PQGSPT 226
Query: 797 GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT 856
A QP A P+ PV +Q P + HPQ S P +PS P +
Sbjct: 227 ASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSA 279
Query: 857 VHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PVQHQAGQAPHLGSGQ-- 908
S P HA LH P P + P QH P P Q GQAP LG+
Sbjct: 280 GQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP-LGTSPAA 337
Query: 909 --PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SPQSSFPQPAAVYAIHHQ 951
P +L P + + PP LPP P A +P P P A H
Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397
Query: 952 QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011
P F+ A++ +++ HP + HPP + L+ PQS P A P P
Sbjct: 398 SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQP----P 451
Query: 1012 ALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGG 1041
L+ S P P HP QP Q P PGG
Sbjct: 452 GLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489
Score = 73.2 bits (178), Expect = 1e-12
Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
SG+ S+ + G M RS + PA S PI + +S + P +S S D
Sbjct: 13 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 70
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
++ ++ K+ + + + ++ + E A + K+ + +E+ +
Sbjct: 71 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 122
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
P+S E + R + +E K++D TS + SP ++++S S
Sbjct: 123 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174
Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
+ + PP AP+G T P PP P PS T PP G P
Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234
Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
A + L+P +P PL + S P++P +H+ P
Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 290
Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
P+ G G +S PQ PQ G A YP+ S +P
Sbjct: 291 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 348
Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
Q + + LP ++ +H P + P + A
Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408
Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
PP A P SS ++P P + P + PS P P L QS SHP
Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468
Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
+ PQ P A+ P P + P +T PA T +QP AA
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 521
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
S G + L + Q ++ +PP P PS + P A+ A ++
Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581
Query: 952 QLPHGFTNMA 961
L G+ + A
Sbjct: 582 HLDRGYNSCA 591
Score = 47.0 bits (110), Expect = 1e-04
Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
P L L HH ++ P P PS SP L ++ L P S+ P+G
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 470
Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
V P PP + P P P P S PP G P +SA P + + + G
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 526
Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
G S P + + + + E P R+ P+ + AR +
Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
N R L + G++ + + E + + +E + KEKE + E
Sbjct: 587 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646
Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S S E + P G P PPP P +G
Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 693
Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
P P L + P SP R H P+ P+L G
Sbjct: 694 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 737
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
LY+ + P ++ ++ + + ++ + R G + P D PA
Sbjct: 738 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 786
Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
+ P + +A PP P++S+ P NP ++ ++P YP +
Sbjct: 787 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 846
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
+ LTS + + + TP H + H + LH HQ P
Sbjct: 847 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 890
Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
+ P A P + + G P+ GQP + L HP T P L
Sbjct: 891 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 950
Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
PP +A Q+ Q A + + QQ HG +M
Sbjct: 951 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 989
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
L PQ PS P QPP Q+ PP + PP G G P P+
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
+TS P GP +A P AA+G + G+ P P Q +E A+
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 546
Query: 99 ARGQSTGKGPPQSP 112
A + PP+SP
Sbjct: 547 AEEPESPPPPPRSP 560
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
G P SS PP P +PGP A + P +G+ T S N+P
Sbjct: 192 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 235
Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
T+ P + + ++P R P +P P P PP+ T SA P S + P
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 290
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
+ P P A ++ +P L PQ G+ P + + L+
Sbjct: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 346
Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
+Q LQ P E L P P P+ K P ++
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406
Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
L P P+SS + PPL P G T+ PPPP
Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 463
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
PP GL + + P A+ P PT P STSTP + GP T
Sbjct: 464 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 511
Query: 691 STPSIPVLTAGQSG 704
+ P P A SG
Sbjct: 512 AQP--PCSGAAASG 523
Score = 38.9 bits (89), Expect = 0.027
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A
Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284
Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
S P+ G G G L P PPQ P A+ + G S P +
Sbjct: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342
Score = 37.0 bits (84), Expect = 0.10
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P Q ++ QQ + + P P G P P S+APPG P +P P A A
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 218
Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
G ++ PQ P P H A A+ R S P SP
Sbjct: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 268
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
QP Q P A + PPG P G P P AT+ P G P A+ P A
Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 241
Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
+ A P P PP P + + GQ + Q P+
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292
Score = 32.3 bits (72), Expect = 2.5
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P PL P + PP T P PP+ P P + +A P PPA L P
Sbjct: 364 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 417
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
+++ + A PPP Q Q Q P + A QS PP
Sbjct: 418 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 79.7 bits (195), Expect = 1e-14
Identities = 162/676 (23%), Positives = 235/676 (34%), Gaps = 158/676 (23%)
Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
GL++ G SP + G+ S++S + +R + A +S P G S
Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70
Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
VPP A SP + +S P P S P DPG P
Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105
Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
A P +S + TD K PGR+ P ++ L+ + R L+E K G
Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
++ S+ + ++ F P L + + ++E ++K + V KE
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201
Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
KPPL +QPP P P Q G G D P+ + +++
Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
E ++P K PT H+ +P+ Q + PQ
Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
V+ + P S S P Q G + P ++ QP A P Q + P +A
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345
Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
P + P P PG ++P P+ + P +GS +
Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+
Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429
Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
P G + + PG G P+ GP S Q + P QLP
Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475
Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
Q G PP PG+ PP Q PP GP + + Q G S PS
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531
Query: 1020 PYPYIGHPQGEQPGQA 1035
P P +QP A
Sbjct: 532 QQPGSAKPSAQQPSPA 547
Score = 68.9 bits (167), Expect = 2e-11
Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)
Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
Q +G E PS K + P V + P G + + + G +PGL S P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432
Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
GP PGPG + GP + S + P + L P+ P + + PPP
Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491
Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
G PP + P A P+P +PP GSA P++ P
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
T VS G G ++SP++ PK L T L E
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
E + G +++E Q K L P SSP+ L P
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
+ K P+ ++ TS + + + PPL G +QPP
Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
+PP ++D+ PVA+ K K PT L+S + +T+ P P
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779
Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
+ S TP + +A S + P P A+ P +S+ PG
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835
Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
+ +G K P Q+ + +P A M A P P S P P+ GQ
Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888
Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
+ P + QS L GS ++ + P+ Q T
Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
S A+ L A QP P + P Q AP+P Q Q P +GQ
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
A S+P ++P + +P A A
Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Score = 57.4 bits (137), Expect = 7e-08
Identities = 142/638 (22%), Positives = 197/638 (30%), Gaps = 114/638 (17%)
Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
P + PK Q P R S S +P S PP P G P++ + P
Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274
Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
AS P+ V S P S S P + +P P + + +P
Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331
Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
+P L + + PG + Q K AQ L P+ P P + P
Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388
Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
K + T P T+ V + PLA G + P + P P + P
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
G I + G +A++ PTKP + PGP
Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476
Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
+ P GPA PQ P S P QQ GS P
Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509
Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
QP A P Q + PP QP +P A PS +
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
+ P T P + S PSA+QP Q L T+ + T+L H P+ A
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605
Query: 877 TTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ--QNLYHPGALTGTPPSLPPGPSAQS 934
T ++ Q+ + PHL + N AL G L P PS+
Sbjct: 606 NFNTCTECQTTVCSLCGFNPN----PHLTEVKEWLCLNCQMKRALGG---DLAPVPSSPQ 658
Query: 935 PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPP 994
P+ A+ T+ A + ++ AP P P L+ P
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPP------LVKQP 710
Query: 995 QSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032
HG P A +LS P P + Q + P
Sbjct: 711 TLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748
Score = 55.1 bits (131), Expect = 4e-07
Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)
Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
+P L + P + SSP P + + P + KA P + + P+ S
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
PP + P PK + AP++ P+ P V ++ + +S+ +
Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775
Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
P + S S +K S K P ++ P E++
Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814
Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K
Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865
Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
D P+ P G P PP P T V + K + EQ ++ +LN +
Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
A + PT P +V T G S S + TAGQ G +S P
Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
QAP P S P G+ A P + + PA+ AP + +
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796
PP + A P + +P ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Score = 51.2 bits (121), Expect = 5e-06
Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P QQP + PPTQQ +P PG SP PGP T PGP + GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456
Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
+A +G + + P PPPQQ ++PG+A S + ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514
Score = 44.7 bits (104), Expect = 5e-04
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
P+QQP+ P +PP Q + PG PP GL PLA T P PP P
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
P L P PP QQ E+PG A+ G GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405
Score = 39.3 bits (90), Expect = 0.021
Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
P +A S + P P P Q + GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565
Score = 37.7 bits (86), Expect = 0.060
Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 62 VAAAGSG--LRRGAEGILAPQPP 82
V+ GSG L+ A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580
Score = 36.6 bits (83), Expect = 0.13
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P + + G+ A QP P +P A Q TG G P P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569
Score = 35.4 bits (80), Expect = 0.30
Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
P P + P Q P P QQA + + G T PP+ LPGP PGP A P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490
Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
P +A + G+ QP P + ++PG+ S Q G P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541
Score = 35.4 bits (80), Expect = 0.30
Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)
Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
S PGP SE++G ++ P K + P + +S P +P + S PP P G+
Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
P +SPK S AP S + P+ + + ASI + S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
+ PG S S + AP + +++ P ++ G+ P K +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996
Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
++ K A KL+P + P + + E + K + LT+EP + + +K
Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625
E E PL + G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074
Score = 34.7 bits (78), Expect = 0.51
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)
Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
+P P + P+QP QQP PP Q +PP G PP G S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383
Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
PGP A A P +G A G P PP QQ A + +
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 106 KGPPQSPV 113
GP ++PV
Sbjct: 434 PGPTKTPV 441
Score = 31.2 bits (69), Expect = 5.6
Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)
Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
E G+EK L + P S + SS + + PP P P PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
PP P T P L K + PV +TL A + P+ + T+
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482
Query: 682 PTSPGPRTHSTPSIPVLT 699
P P+ S PS V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500
Score = 30.4 bits (67), Expect = 9.6
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
+++E+K+ LEE + KL P +S+PE +LK + + E++++G +
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282
Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
+ + +T+ P P + EQP PPC ++ G K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342
Query: 646 DE 647
D+
Sbjct: 1343 DD 1344
Score = 30.4 bits (67), Expect = 9.6
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
+ E K+ + R G SS E L +LKE+ K +E E
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
K+ S K+DK L E P+ PP P + SP L + + +E
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855
Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
+E +P E +P K ++ V K PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 79.7 bits (195), Expect = 1e-14
Identities = 162/676 (23%), Positives = 235/676 (34%), Gaps = 158/676 (23%)
Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
GL++ G SP + G+ S++S + +R + A +S P G S
Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70
Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
VPP A SP + +S P P S P DPG P
Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105
Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
A P +S + TD K PGR+ P ++ L+ + R L+E K G
Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
++ S+ + ++ F P L + + ++E ++K + V KE
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201
Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
KPPL +QPP P P Q G G D P+ + +++
Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
E ++P K PT H+ +P+ Q + PQ
Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
V+ + P S S P Q G + P ++ QP A P Q + P +A
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345
Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
P + P P PG ++P P+ + P +GS +
Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+
Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429
Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
P G + + PG G P+ GP S Q + P QLP
Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475
Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
Q G PP PG+ PP Q PP GP + + Q G S PS
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531
Query: 1020 PYPYIGHPQGEQPGQA 1035
P P +QP A
Sbjct: 532 QQPGSAKPSAQQPSPA 547
Score = 68.9 bits (167), Expect = 2e-11
Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)
Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
Q +G E PS K + P V + P G + + + G +PGL S P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432
Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
GP PGPG + GP + S + P + L P+ P + + PPP
Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491
Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
G PP + P A P+P +PP GSA P++ P
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
T VS G G ++SP++ PK L T L E
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
E + G +++E Q K L P SSP+ L P
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
+ K P+ ++ TS + + + PPL G +QPP
Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
+PP ++D+ PVA+ K K PT L+S + +T+ P P
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779
Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
+ S TP + +A S + P P A+ P +S+ PG
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835
Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
+ +G K P Q+ + +P A M A P P S P P+ GQ
Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888
Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
+ P + QS L GS ++ + P+ Q T
Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
S A+ L A QP P + P Q AP+P Q Q P +GQ
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
A S+P ++P + +P A A
Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Score = 57.4 bits (137), Expect = 7e-08
Identities = 142/638 (22%), Positives = 197/638 (30%), Gaps = 114/638 (17%)
Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
P + PK Q P R S S +P S PP P G P++ + P
Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274
Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
AS P+ V S P S S P + +P P + + +P
Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331
Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
+P L + + PG + Q K AQ L P+ P P + P
Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388
Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
K + T P T+ V + PLA G + P + P P + P
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
G I + G +A++ PTKP + PGP
Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476
Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
+ P GPA PQ P S P QQ GS P
Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509
Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
QP A P Q + PP QP +P A PS +
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
+ P T P + S PSA+QP Q L T+ + T+L H P+ A
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605
Query: 877 TTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ--QNLYHPGALTGTPPSLPPGPSAQS 934
T ++ Q+ + PHL + N AL G L P PS+
Sbjct: 606 NFNTCTECQTTVCSLCGFNPN----PHLTEVKEWLCLNCQMKRALGG---DLAPVPSSPQ 658
Query: 935 PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPP 994
P+ A+ T+ A + ++ AP P P L+ P
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPP------LVKQP 710
Query: 995 QSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032
HG P A +LS P P + Q + P
Sbjct: 711 TLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748
Score = 55.1 bits (131), Expect = 4e-07
Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)
Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
+P L + P + SSP P + + P + KA P + + P+ S
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
PP + P PK + AP++ P+ P V ++ + +S+ +
Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775
Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
P + S S +K S K P ++ P E++
Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814
Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K
Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865
Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
D P+ P G P PP P T V + K + EQ ++ +LN +
Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
A + PT P +V T G S S + TAGQ G +S P
Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
QAP P S P G+ A P + + PA+ AP + +
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796
PP + A P + +P ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Score = 51.2 bits (121), Expect = 5e-06
Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P QQP + PPTQQ +P PG SP PGP T PGP + GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456
Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
+A +G + + P PPPQQ ++PG+A S + ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514
Score = 44.7 bits (104), Expect = 5e-04
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
P+QQP+ P +PP Q + PG PP GL PLA T P PP P
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
P L P PP QQ E+PG A+ G GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405
Score = 39.3 bits (90), Expect = 0.021
Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
P +A S + P P P Q + GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565
Score = 37.7 bits (86), Expect = 0.060
Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 62 VAAAGSG--LRRGAEGILAPQPP 82
V+ GSG L+ A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580
Score = 36.6 bits (83), Expect = 0.13
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P + + G+ A QP P +P A Q TG G P P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569
Score = 35.4 bits (80), Expect = 0.30
Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
P P + P Q P P QQA + + G T PP+ LPGP PGP A P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490
Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
P +A + G+ QP P + ++PG+ S Q G P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541
Score = 35.4 bits (80), Expect = 0.30
Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)
Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
S PGP SE++G ++ P K + P + +S P +P + S PP P G+
Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
P +SPK S AP S + P+ + + ASI + S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
+ PG S S + AP + +++ P ++ G+ P K +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996
Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
++ K A KL+P + P + + E + K + LT+EP + + +K
Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625
E E PL + G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074
Score = 34.7 bits (78), Expect = 0.51
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)
Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
+P P + P+QP QQP PP Q +PP G PP G S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383
Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
PGP A A P +G A G P PP QQ A + +
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 106 KGPPQSPV 113
GP ++PV
Sbjct: 434 PGPTKTPV 441
Score = 31.2 bits (69), Expect = 5.6
Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)
Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
E G+EK L + P S + SS + + PP P P PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
PP P T P L K + PV +TL A + P+ + T+
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482
Query: 682 PTSPGPRTHSTPSIPVLT 699
P P+ S PS V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500
Score = 30.4 bits (67), Expect = 9.6
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
+++E+K+ LEE + KL P +S+PE +LK + + E++++G +
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282
Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
+ + +T+ P P + EQP PPC ++ G K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342
Query: 646 DE 647
D+
Sbjct: 1343 DD 1344
Score = 30.4 bits (67), Expect = 9.6
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
+ E K+ + R G SS E L +LKE+ K +E E
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
K+ S K+DK L E P+ PP P + SP L + + +E
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855
Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
+E +P E +P K ++ V K PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 79.3 bits (194), Expect = 2e-14
Identities = 113/436 (25%), Positives = 142/436 (32%), Gaps = 58/436 (13%)
Query: 580 EKEVDGLLTSEPMGSPVS--SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
++E L+ P G+P +K + KP P G P+ PPPP G PP
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 83
Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
+G +K +GP + K +P P P P P+ + P P
Sbjct: 84 ---QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPP 133
Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSD 757
G+ PQ + PQ GP P P ++ G PPQ +
Sbjct: 134 PPPGKPQGPPPQGGNK-PQ---GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189
Query: 758 QHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPM 817
Q Q PP GPP P P P PG+P P SQ +P
Sbjct: 190 QPQGPPPPP----GKPQGPP-----PQGGNKPQGPPP-PGKPQGPPPQGDNKSQSARSP- 238
Query: 818 LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPAT 877
P+ G PQ + PQ P PQ P P P
Sbjct: 239 -PGKPQ----GPPPQG---GNQPQGPPPPPGKPQG---------PPPQGGNKPQGPPPPG 281
Query: 878 TPTGSQPQS---QHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPP---SLPPGPS 931
P G PQ ++ SP G P G QPQ PG G PP + P GP
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340
Query: 932 AQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVML 990
PQ P P + P G + + G PPP G P PQ
Sbjct: 341 PPGKPQG--PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQPQAPP 395
Query: 991 LHPPQSHGGPPQGAVP 1006
PQ PPQG P
Sbjct: 396 AGQPQGPPRPPQGGRP 411
Score = 73.6 bits (179), Expect = 1e-12
Identities = 102/393 (25%), Positives = 128/393 (32%), Gaps = 67/393 (17%)
Query: 555 QPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-KTESVSDKEDKPPLA 613
QP P P P + P+G K +P G P K+ S KP
Sbjct: 67 QPQGPP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
P G P+ PPPP G PP +G +K +GP P K P P
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQ 165
Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYP 730
NKS S+ + PG P G PQ P GP Q PQ P
Sbjct: 166 GDNKSRSSRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216
Query: 731 YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPY 790
P GK +G PPQ ++ Q A +PP GPP P P
Sbjct: 217 PP---------GKPQGP----PPQGDNKSQSARSPP----GKPQGPP-----PQGGNQPQ 254
Query: 791 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850
P PG+P P Q P P+ G PQ S + + P + P
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQGGSKSRSSRSPPGKPQGP 307
Query: 851 QALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ 910
Q P + PQ P G P + P P ++ G+PQ
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367
Query: 911 QNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPA 943
P G P PP P+ +PQ PA
Sbjct: 368 ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396
Score = 68.6 bits (166), Expect = 3e-11
Identities = 112/418 (26%), Positives = 129/418 (30%), Gaps = 62/418 (14%)
Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQ--SGLYS 707
VA S N N P L P G + PS P G G
Sbjct: 8 VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67
Query: 708 PQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764
PQ P GP Q PQ P P GK +G PPQ P S
Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDKSRSPRSP 114
Query: 765 PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824
P Q GPP P P P PG+P P Q P P+
Sbjct: 115 PGKPQ-----GPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ- 160
Query: 825 LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884
G PQ S + + P + P Q P + PQ P G P
Sbjct: 161 ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 885 QSQHAAPSPVQHQAGQA-----------PHLGSGQPQQNLYHPGALTGTPP---SLPPGP 930
+ P P Q+ P G QPQ PG G PP + P GP
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277
Query: 931 SAQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
PQ P P + P G + G PPP PG P P
Sbjct: 278 PPPGKPQG--PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG----PPPPPGKPQGPPPQ 331
Query: 990 LLHPPQSHGGP--PQGAVPQSGVPALSASTPSPYPYIGHPQ--GEQPGQAPGFPGGAD 1043
+ PQ P PQG PQ G + SA +P P G PQ G P Q P P G +
Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNP-QGPPPPAGGN 387
Score = 64.7 bits (156), Expect = 5e-10
Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 57/435 (13%)
Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP 394
S ESPSL + + P PQ + P+G G P P+GP GP
Sbjct: 24 SQEESPSLIAGNPQGAP-PQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81
Query: 395 GSEARGINGGPSRMSPKAQRPLRGAKTLS--SPSNRPSGET--------SVPPPPAVGRM 444
+ GP P +G K+ S SP +P G PPPP +
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141
Query: 445 YPPRSP-KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
PP+ K P P PP G SS S P P G+ P P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201
Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPE 561
+P P + G P N+ + + + G Q QP P
Sbjct: 202 QGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257
Query: 562 NSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTE 619
P P + P+G K +P G P SK+ S KP P G
Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
P+ PPPP G PP +G +K +GP P KP
Sbjct: 314 QPQGPPPPPGKPQGPPP----QGGNKPQGPPP----------------PGKP-------Q 346
Query: 680 STPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
P G ++ S S P G PQ PQ PA PQ P + G
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQG-----PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401
Query: 740 QQGKYRGAKGSLPPQ 754
+G + S PPQ
Sbjct: 402 PPRPPQGGRPSRPPQ 416
Score = 61.2 bits (147), Expect = 5e-09
Identities = 104/431 (24%), Positives = 134/431 (31%), Gaps = 57/431 (13%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSA 453
P A G P + K Q P P + + PPPP PP +
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 454 APAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKE 513
P P+ P + S P P G P P P K
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPP 144
Query: 514 PG--RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPENSLDPFPP 569
G + P + G P N+ + + + G Q QP P P P
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-----PPPG 199
Query: 570 RILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
+ P+G K +P G P +K++S KP P G P+ PPPP
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP 687
G PP +G +K +GP P K P P +KS S+ + PG
Sbjct: 260 PGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQGGSKSRSSRSPPGK 303
Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKY 744
P G PQ P GP Q PQ P P P QG
Sbjct: 304 PQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354
Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP-GQP--AM 801
+ PP + PP + GPP P + P PQ P GQP
Sbjct: 355 KSRSARSPPGK------PQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403
Query: 802 MQPMAHYPSQP 812
P PS+P
Sbjct: 404 RPPQGGRPSRP 414
Score = 51.6 bits (122), Expect = 4e-06
Identities = 58/204 (28%), Positives = 64/204 (31%), Gaps = 28/204 (13%)
Query: 886 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 945
SQ +PS + AP G +PQ PG G PP PQ P P
Sbjct: 24 SQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQ-----GGNQPQGPPPPPGK- 77
Query: 946 YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH--PPQVMLLHPPQSHGGPPQG 1003
P G Q G PP PG P PPQ P+S G PQG
Sbjct: 78 --------PQG---------PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120
Query: 1004 AVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAP 1063
PQ G P P PQG Q P PG +S S R P
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRS---PP 177
Query: 1064 GSVLCFPPSSLSCDPAAPLPTASP 1087
G PP + P P P
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKP 201
Score = 48.9 bits (115), Expect = 3e-05
Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 25/131 (19%)
Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
KPQ P +PQ PPP + AR PPG G + P G P P PP
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270
Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGS 98
GPP P GP GS R PQ PPPQ + PG
Sbjct: 271 GNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329
Query: 99 ARGQSTGKGPP 109
+G + +GPP
Sbjct: 330 PQGGNKPQGPP 340
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%)
Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
KPQ P +PQ PPP ++ +R PPG G + P G P P PP
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332
Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ---HQERPGAAAIGSARG 101
GPP P GP GS R PQ PP Q+ Q P A +
Sbjct: 333 GNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391
Query: 102 QSTGKGPPQSP 112
Q+ G PQ P
Sbjct: 392 QAPPAGQPQGP 402
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
KPQ P Q +QPQ PPP PP G + P G P GP ++ +P
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238
Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
PG PP + GP G +G PQ PPP + P +R
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298
Query: 104 TGKGPPQSPVFEG 116
+ G PQ P +G
Sbjct: 299 SPPGKPQGPPPQG 311
Score = 47.4 bits (111), Expect = 8e-05
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
KPQ P Q +QPQ PPP PP G + P G P GP +S +P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176
Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
PG PP + GP G +G PQ PPP + P ++
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236
Query: 104 TGKGPPQSPVFEG 116
+ G PQ P +G
Sbjct: 237 SPPGKPQGPPPQG 249
Score = 45.4 bits (106), Expect = 3e-04
Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 23/131 (17%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
KPQ P Q +QPQ PPP PP G + P G P GP +S +P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQHQERP--GAAAIGSAR 100
PG PP + GP G +G PQ PPPP + Q P G + SAR
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360
Query: 101 G-QSTGKGPPQ 110
+GPPQ
Sbjct: 361 SPPGKPQGPPQ 371
Score = 45.1 bits (105), Expect = 4e-04
Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 12/109 (11%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
KPQ P Q +QPQ PPP PP G + P G P P GPP
Sbjct: 56 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQGPPPQGDKSRS 110
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
P + G +G PQ PPP PG +G + +GPP
Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPP 154
Score = 44.3 bits (103), Expect = 6e-04
Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 16/117 (13%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-----PPAAA 55
KPQ P Q ++PQ PPP +P G PP GG +S +PPG PP
Sbjct: 262 KPQGPPPQGGNKPQGPPP-----PGKPQG--PPPQGG--SKSRSSRSPPGKPQGPPPQGG 312
Query: 56 SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
+ GP G +G PQ PPP + P +R + G PQ P
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 24/130 (18%)
Query: 3 KPQPLQQPSQPQQPPPT--QQAVARRPPG--------GTSPPNGGLPGPLATSAAPP--- 49
KPQ P +PQ PPP + R PPG G + P G P P PP
Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147
Query: 50 ----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGSA 99
GPP P GP + R PQ PPPQ + PG
Sbjct: 148 NKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 100 RGQSTGKGPP 109
+G + +GPP
Sbjct: 207 QGGNKPQGPP 216
Score = 37.0 bits (84), Expect = 0.10
Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 9/105 (8%)
Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
PQ PP + PP P G P P + P GPP GP G +G
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGN-QPQGPPPPPGKPQGP-PPQGGNKPQG 91
Query: 73 AEGILAPQPPPPQQHQER-----PGAAAIGSARGQSTGKGPPQSP 112
PQ PPPQ + R PG +G + +GPP P
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Score = 31.6 bits (70), Expect = 4.3
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 12/61 (19%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
KPQ P Q+ + PQ PP PP G +P P P PP PP P
Sbjct: 365 KPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 414
Query: 61 P 61
P
Sbjct: 415 P 415
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 73.9 bits (180), Expect = 8e-13
Identities = 186/803 (23%), Positives = 291/803 (36%), Gaps = 125/803 (15%)
Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
P P V + + S+S G P + + P GP L P GS + + PS +
Sbjct: 1036 PTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVL---PSPLG- 1091
Query: 411 KAQRPLRGAKTLSSPSNRPSGETSV-PPPPAVGRMYPPRSPKSAA---PAPISASCPEPP 466
LS S P+ S+ P PPA R+ P P S++ P + PP
Sbjct: 1092 ----------VLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPP 1141
Query: 467 IGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARI 526
+ +++ + T++V P +PA ++ L+P L + G + +LA +
Sbjct: 1142 AAATTTSTTTATATTTAVPAP-----TPAPQRLILSPDMQARLPS---GEVVSIGQLASL 1193
Query: 527 AGKVPGLQNEQK--RFQLE--ELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582
A + K FQ++ +L GAQ + ++ +P+ ++
Sbjct: 1194 AQRPVANAGGSKPLTFQIQGNKLTLTGAQVR----------------QLAVGQPRPLQRN 1237
Query: 583 VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIK 641
V L+++ +S + P P+ + P P P+ TG S P+ +
Sbjct: 1238 VVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQ 1297
Query: 642 GED---KDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSPGPRTHSTPS-- 694
+ G V V+++ + P PL + S+ P PR TP
Sbjct: 1298 VPPTMVNNTGVVKIVVRQAPRD----GLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRL 1353
Query: 695 -IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPP 753
P L ++ + +P + + ++ P+ + VS S PG + +P
Sbjct: 1354 PTPTLGTARAPMPTPTLVRPLLKLVHSPSPE--------VSASAPGAAPLTISSPLHVP- 1404
Query: 754 QRSDQHQPASAP-PMMQAAAAAGP-PLVAATPYSSYIPYN-PQQFPGQPAMMQPMAHYPS 810
S PAS+P P+ ++ A P + P SS +P + P P P + +
Sbjct: 1405 --SSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPA------PASAPLT 1456
Query: 811 QPVFAPML--QSNPRMLTSGSHPQAIVSSSTP----QYPSAEQPTPQAL---YATV---- 857
P+ AP+ S P +LTS + P A V + P PS P+ AL AT
Sbjct: 1457 IPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLS 1516
Query: 858 HQSYPHHATQL---HAHQP----------QPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
P H L +H P P P + +AP+P QA
Sbjct: 1517 SSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPA 1576
Query: 905 GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSF----PQPAAVYAIHHQQLPHGFTNM 960
S Q L P A P + PS P + P P A + Q P
Sbjct: 1577 SSA--SQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP 1634
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQG----AVPQSGVPALSAS 1016
+ + + P AP Q ML P S P A+ + P L S
Sbjct: 1635 SSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGS 1694
Query: 1017 TPSPYPYI--GHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSL 1074
+PS + G+PQG P Q + ++ ++ S LAPG L P +L
Sbjct: 1695 SPSQTLSLGTGNPQGPFPTQTLSLTPASS--LVPTPAQTLS-----LAPGPPL-GPTQTL 1746
Query: 1075 SCDPAAPLPTASPALSDPDCLLT 1097
S PA PL ASP P LT
Sbjct: 1747 SLAPAPPLAPASPVGPAPAHTLT 1769
Score = 65.5 bits (158), Expect = 3e-10
Identities = 157/712 (22%), Positives = 250/712 (35%), Gaps = 167/712 (23%)
Query: 287 EEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASRE 346
EE + E A L ++ +Y ++ + + + EE A ++ + R+ A E
Sbjct: 2293 EEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEE 2352
Query: 347 GKYIPLPQRVREGPRGGVRCSSSRGG----RPGLSSLPPRGPHHLDNSSPGPGSEARGIN 402
LPQ EGP G S GG R + P R + G +E +G N
Sbjct: 2353 --VFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGAN 2410
Query: 403 -------------GGPSRMSPKAQR-PLRGAKTLSSPSNRPSGETSV------------- 435
P R SP +R P + +P++ P+ ++
Sbjct: 2411 HTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISA 2470
Query: 436 --------------PPPPAVGRMYPPRSPKSAAPAPISASCP---EPPIGSAVPTSSA-- 476
PPPP+ PP S + P P P PP + + T S+
Sbjct: 2471 PNPITILPVHILPSPPPPS---QIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPL 2527
Query: 477 -----SIPVTSSVSDPGVG-----------------------------SISPASPKISLA 502
S+P+++SV++ +G S+S PK L
Sbjct: 2528 LLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPK-DLL 2586
Query: 503 PTDVKELSTKEPGRTLEPQ--ELARIAGKVPGLQNEQKRFQLE--ELRKFGAQFKLQPSS 558
P V+ L E +L P L AG +P Q ++ E L +L
Sbjct: 2587 PVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCV 2646
Query: 559 SPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM---GSPVSS--KTESVSDKEDKPPLA 613
S N L+ PP +EP + E D TSE + +P SS K + + E P
Sbjct: 2647 SESNGLE-LPPSAASDEPLQEPLEAD--RTSEELTEAKTPTSSPEKPQELVTAEVAAPST 2703
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGED--------------KDEGPVAEQVKKSTL 659
S T PE P P P + + I+G+ K G + V++ L
Sbjct: 2704 SSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKEL 2763
Query: 660 NPNAKEFNPTKPLL--SVNKSTSTPTSPGPRTHSTPSI------PVLTAGQSGLYSPQYI 711
++ L V++++++P SP R+ S P P A S L +P
Sbjct: 2764 VRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQ 2823
Query: 712 SYIPQIHMGPAVQ---APQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768
+I + H+ V +P+ + P + RG PP+++ PA A +
Sbjct: 2824 PFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGR----PPKKN--RSPADAGRGV 2877
Query: 769 QAAAAA-------------GP-PLVAATPYSSYIPYNPQQFPG-QPAMMQPMAHYPSQPV 813
A ++ GP L+ A P PQ PG QP QP+ H P+ P+
Sbjct: 2878 DEAPSSTLKGKTNGADPVPGPETLIVADPV-----LEPQLIPGPQPLGPQPV-HRPN-PL 2930
Query: 814 FAPMLQSN------------PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL 853
+P+ + P ++S + + P +PS P P L
Sbjct: 2931 LSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLL 2982
Score = 63.9 bits (154), Expect = 8e-10
Identities = 126/539 (23%), Positives = 189/539 (35%), Gaps = 70/539 (12%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGI-NGGP--SRMSPKAQRPLRGAKTLSSPSNRPS 430
PG + L P H+ +S PGP S I N P S +S PL + +S P
Sbjct: 1390 PGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP----- 1444
Query: 431 GETSVPPPPAVGRMYPPRSPKS-AAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489
T++P P + P +P + +A P + PP+ VP + P S++ G
Sbjct: 1445 --TTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAA----PGPPSLAPSGA 1498
Query: 490 GSISPASPKISLAPTDVKELSTKE-PGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548
SP++ ++L LS+ + PG P LA + VPGL +
Sbjct: 1499 ---SPSASALTLGLATAPSLSSSQTPG---HPLLLAPTSSHVPGLNST------------ 1540
Query: 549 GAQFKLQPSSSPENSL-DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKE 607
P P ++L PFP P + L +P SS +++++
Sbjct: 1541 -VAPACSPVLVPASALASPFP-----SAPNPAPAQASLL-------APASSASQALATPL 1587
Query: 608 DKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFN 667
P AP P PP P +P G + PV ST + +
Sbjct: 1588 -APMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASAS 1646
Query: 668 PTKPLLSVNKSTSTPT-------SPGPRTHSTPSI---PVLTAGQSGLYSPQYISYIPQI 717
P V +ST T SP P ST ++ P L G Q +S
Sbjct: 1647 PVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGN 1706
Query: 718 HMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
GP + P S+ VP A G PP Q + P + A+ GP
Sbjct: 1707 PQGP-FPTQTLSLTPASSLVPTPAQTLSLAPG--PPLGPTQTLSLAPAPPLAPASPVGP- 1762
Query: 778 LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQ-PVFAPMLQSNPRMLTSGSHPQAIVS 836
A + P + PA +Q + P+ P P + + + A +
Sbjct: 1763 --APAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQA 1820
Query: 837 SSTPQYPSAEQPTPQALYATVHQSYPHHAT-QLHAHQPQPATTPT---GSQPQSQHAAP 891
SS S P P + + + S T L + P P +T T G +P+ Q P
Sbjct: 1821 SSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPP 1879
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/368 (25%), Positives = 124/368 (33%), Gaps = 72/368 (19%)
Query: 339 SPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEA 398
S + +S EG P R R +R + GRPG P GP L PG
Sbjct: 2705 SSATSSPEGPSPARPPRRRTSADVEIRGQGT--GRPG----QPPGPKVL-RKLPG----- 2752
Query: 399 RGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPP-PPAVGRMYPPRS------PK 451
R + + + +R RGA + P ETS P P+V M P S P
Sbjct: 2753 RLVTVVEEKELVRRRRQQRGAASTLVPG---VSETSASPGSPSVRSMSGPESSPPIGGPC 2809
Query: 452 SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS----DPGVGSISPASPKISLAPTDVK 507
AAP S+S P PP + + VT S D + +I+P + K K
Sbjct: 2810 EAAP---SSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKK 2866
Query: 508 ELSTKEPGRTLEPQELARIAGK------VPGLQNEQKRFQLEELRKFGAQFKL--QPSSS 559
S + GR ++ + + GK VPG + + E + L QP
Sbjct: 2867 NRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHR 2926
Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619
P L P R PK ++ + G ++S A G +E
Sbjct: 2927 PNPLLSPVEKRRRGRPPKARDLPIPGTISS-----------------------AGDGNSE 2963
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
QPPP T PP L+ V ST P K P K
Sbjct: 2964 SRTQPPPHPSPLTPLPP--LLVCPTATVANTVTTVTISTSPPKRKRGRPPK--------- 3012
Query: 680 STPTSPGP 687
P SP P
Sbjct: 3013 -NPPSPRP 3019
Score = 37.7 bits (86), Expect = 0.060
Identities = 68/230 (29%), Positives = 87/230 (37%), Gaps = 41/230 (17%)
Query: 801 MMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPS-AEQPTPQALYATVHQ 859
M+QP+ P Q ++ +NPR P V P P + QPTP V Q
Sbjct: 997 MLQPV---PKQEGRTVVVVNNPRA------PLGPVPVRPPPGPELSAQPTP----GPVPQ 1043
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP-GA 918
P A+ + + P S+P P P+Q +G P Q L P G
Sbjct: 1044 VLP--ASLMVSASPAGPPLIPASRPPGPVLLP-PLQPNSGSLP--------QVLPSPLGV 1092
Query: 919 LTGT--PP----SLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFT---NMAHVTQAHVQ 969
L+GT PP SL P P A S P P + + +P G+T A T
Sbjct: 1093 LSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTA 1152
Query: 970 TGITAAPPPHPGAPHP-PQVMLLHPPQSHGGPPQGAVPQSGVPALSASTP 1018
T T A P AP P PQ ++L P P G V G A A P
Sbjct: 1153 TATTTAVP----APTPAPQRLIL-SPDMQARLPSGEVVSIGQLASLAQRP 1197
Score = 37.4 bits (85), Expect = 0.078
Identities = 82/327 (25%), Positives = 115/327 (35%), Gaps = 57/327 (17%)
Query: 423 SSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
SSPS S T P P P P S PA + P PP+G S A P
Sbjct: 1694 SSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPP 1753
Query: 481 TSSVSDPGVG-----SISPASPKISL-APTDVKELS-TKEPGRTLEPQELARIAGKVPGL 533
+ S G +++PAS SL AP V+ L+ + P TL P +A
Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
Q+ + + GA P P ++ P K+ E D L
Sbjct: 1814 QSPASQASSLVVSASGAA--------------PLPVTMVSRLPVSKD-EPDTLTLRSGPP 1858
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQ 653
SP P A S G P + PPP P P L E+K + +E+
Sbjct: 1859 SP--------------PSTATSFGGPRPRRQPPPPPRS----PFYLDSLEEKRKRQRSER 1900
Query: 654 VKK--------STLNP-NAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSG 704
+++ L P E L S P SPGP +H T A ++
Sbjct: 1901 LERIFQLSEAHGALAPVYGTEVLDFCTLPQPVASPIGPRSPGP-SHPTFWTYTEAAHRAV 1959
Query: 705 LYSPQYISYIPQ-----IHMGPAVQAP 726
L+ Q + + + I + P V+AP
Sbjct: 1960 LFPQQRLDQLSEIIERFIFVMPPVEAP 1986
Score = 37.0 bits (84), Expect = 0.10
Identities = 30/107 (28%), Positives = 40/107 (37%), Gaps = 8/107 (7%)
Query: 7 LQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAG 66
L P P Q PP PP T PP P P T P P P P++A+
Sbjct: 2482 LPSPPPPSQIPPCSSPACTPPPACTPPP-AHTPPPAQTCLVTPSSPLLLGPPSVPISASV 2540
Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGA---AAIGSARGQSTGKGPPQ 110
+ L G L P+ Q P + A++ S+ S PP+
Sbjct: 2541 TNLPLG----LRPEAELCAQALASPESLELASVASSETSSLSLVPPK 2583
Score = 33.5 bits (75), Expect = 1.1
Identities = 59/227 (25%), Positives = 86/227 (37%), Gaps = 37/227 (16%)
Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT 922
+H + AHQ + TTP P ++ P P AP +P+ P +
Sbjct: 2410 NHTPVISAHQTRSTTTPPRCSP-ARERVPRP-------AP-----RPRPT---PASAPAA 2453
Query: 923 PPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGA 982
P+L P P + S P P + +H P + + + + T A PP
Sbjct: 2454 IPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCS-SPACTPPPACTPPPAHT 2512
Query: 983 PHPPQVMLLHPPQS-HGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGG 1041
P P Q L+ P GPP +VP +SAS + P P+ E QA P
Sbjct: 2513 PPPAQTCLVTPSSPLLLGPP--SVP------ISASVTN-LPLGLRPEAELCAQALASPES 2563
Query: 1042 ADDRILCRVGRSHSRR-----RQGLAPGSVLCFPPS--SLSCDPAAP 1081
+ L V S + + L P +V P S +LS P+AP
Sbjct: 2564 LE---LASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAP 2607
Score = 32.7 bits (73), Expect = 1.9
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP-AAASPCLGPV 62
P +PPP + A+ PG P LP L SA+P GPP AS GPV
Sbjct: 1023 PVRPPPGPELSAQPTPG---PVPQVLPASLMVSASPAGPPLIPASRPPGPV 1070
Score = 32.3 bits (72), Expect = 2.5
Identities = 65/264 (24%), Positives = 86/264 (32%), Gaps = 56/264 (21%)
Query: 404 GPSRMSPKAQRPLRGAKTLSSP-----SNRPSGETSVPPPPAVG---------RMYPPRS 449
GP + P+ P+ L SP RP +P P + R PP
Sbjct: 2915 GPQPLGPQ---PVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPH 2971
Query: 450 PKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP----GVGSISPASPKISLAPT- 504
P P P CP + + V T VT S S P G +P SP+ S P
Sbjct: 2972 PSPLTPLPPLLVCPTATVANTVTT------VTISTSPPKRKRGRPPKNPPSPRPSQLPVL 3025
Query: 505 DVKELSTKEP---GRTLEPQELARIAGKVPGLQNEQKRFQLEEL---------RKFGA-- 550
D S E GR +PQ G + +L L RK G
Sbjct: 3026 DRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSM 3085
Query: 551 -----QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD 605
Q L + S L+ PP ++ PK + + P +TE +
Sbjct: 3086 VVAVIQDDLDLADSGPGGLELTPP-VVSLTPKLRSTRL------RPGSLVPPLETEKLPR 3138
Query: 606 KEDKPPLAPSGG--TEGPEQPPPP 627
K P+ S G G QPP P
Sbjct: 3139 KRAGAPVGGSPGLAKRGRLQPPSP 3162
Score = 32.0 bits (71), Expect = 3.3
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 12/106 (11%)
Query: 10 PSQPQQPPPTQQ-AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
P+ P P Q ++A PP G + P P A+P GP A + L P +++ S
Sbjct: 1720 PASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASL 1779
Query: 69 LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP--PQSP 112
L + L P P +G A Q+ P QSP
Sbjct: 1780 LAPASVQTLTLSPAP---------VPTLGPAAAQTLALAPASTQSP 1816
Score = 30.4 bits (67), Expect = 9.6
Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 5/110 (4%)
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYN-PQQFPGQPAMMQPMAHYPSQ 811
P R +PA P A+A A P + P S+ +P + P P + P PSQ
Sbjct: 2431 PARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQ 2490
Query: 812 --PVFAPMLQSNPRMLTSGSH--PQAIVSSSTPQYPSAEQPTPQALYATV 857
P +P P +H P A TP P P + A+V
Sbjct: 2491 IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASV 2540
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 73.9 bits (180), Expect = 8e-13
Identities = 142/556 (25%), Positives = 194/556 (34%), Gaps = 114/556 (20%)
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
+ P G ++ LLTS SP+ ++ S E P AP P+ + G
Sbjct: 352 QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690
G KD G A+ S A++ + P +S P +PGP R+
Sbjct: 408 GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456
Query: 691 STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
+P P++ G + PQ S P GP PQ YP + PG
Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514
Query: 744 YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
+ + +PPQ S Q QP PP Q
Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557
Query: 787 YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844
Y+P QQ + Q M Q SQP AP ++ + L P SS P
Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612
Query: 845 AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
+ P AT+ + +T Q PA +P S HA+P G +P
Sbjct: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667
Query: 904 -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955
+GS Q + P ++ G+ P PPG +QS SS P A+ +P
Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719
Query: 956 GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002
GF N QTG + +P P PG + S G GP PQ
Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779
Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRR 1058
G + SGVP+ S S P P I + GQ P P GA +GR S
Sbjct: 780 GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA-----VPLGRMPSAGM 833
Query: 1059 QGLA-PGSVLCFPPSS 1073
Q PG++ PSS
Sbjct: 834 QNRPFPGNMSSMTPSS 849
Score = 62.4 bits (150), Expect = 2e-09
Identities = 156/758 (20%), Positives = 246/758 (32%), Gaps = 143/758 (18%)
Query: 321 RTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLP 380
R +E +AV + + S SR+G + + Q G+ SSS +P +S
Sbjct: 869 RKAQEAAAAVMQAAAN----SAQSRQGSFPGMNQ-------SGLMASSSPYSQPMNNS-- 915
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
L N+ P S A + + A G L P E P P +
Sbjct: 916 ----SSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 971
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
+ S P P + P P S+ SS + S+S PG +P+SPK S
Sbjct: 972 KSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPK-TPSSPKSS 1030
Query: 501 LAPTDVKELST-----KEPGRTL------------------------EPQELARI---AG 528
+ T ++++ EP R L +P +L R+
Sbjct: 1031 SSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVK 1090
Query: 529 KVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLT 588
++ GL K ++ R+ + SSS +SL K++ + L
Sbjct: 1091 EIGGLAQVNKN---KKWRELATNLNVGTSSSAASSL--------------KKQYIQYLFA 1133
Query: 589 SE---PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDK 645
E G + S D + +P L P P P TGS + + G+ K
Sbjct: 1134 FECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLK 1193
Query: 646 DEGPVA---------EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI- 695
P + + + ST++ + F+ +++ TP +P + S P +
Sbjct: 1194 PPTPASTPHGQMTPMQGGRSSTISVH-DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVM 1252
Query: 696 -----------------------PVLTAGQ------SGLYSPQYISYIPQIHMGPAVQAP 726
P +T GQ +Y+ + + MG Q P
Sbjct: 1253 GRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFP 1312
Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM----MQAAAAAGPPL---- 778
Y + GQQ +G PP HQP P GPP
Sbjct: 1313 YGASYDRRHEPYGQQYPGQGPPSGQPPYGG--HQPGLYPQQPNYKRHMDGMYGPPAKRHE 1370
Query: 779 --VAATPYSSYIPYNPQQFPGQ---PAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
+ YSS Q+ G P YP P +Q ++ T G PQ
Sbjct: 1371 GDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYP-YPYSRERMQGPGQIQTHGIPPQ- 1428
Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893
+ Q S+E P A YP+ Q Q P ++
Sbjct: 1429 -MMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQR 1487
Query: 894 VQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQ------SSFPQPAAVY- 946
+ H++ H+ QP Y + + P + PP PS Q+P S P PA+
Sbjct: 1488 INHESQWPSHVSQRQP----YMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQR 1543
Query: 947 AIHHQQLPHGFTNMAHVTQAHVQ----TGITAAPPPHP 980
++ ++ P + + V T PPP P
Sbjct: 1544 SLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQP 1581
Score = 54.3 bits (129), Expect = 6e-07
Identities = 155/707 (21%), Positives = 229/707 (32%), Gaps = 111/707 (15%)
Query: 374 PG-LSSLPPRGPHHLDNSSPGPGSEARGIN----------------GGPSRMSPKAQRPL 416
PG +SS+ P P PG G +N SR
Sbjct: 839 PGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQ 898
Query: 417 RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSA 476
G SSP ++P +S M P S APA +++S + + +
Sbjct: 899 SGLMASSSPYSQPMNNSS-------SLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGES 951
Query: 477 SIPVTSSVSDPGVGSISPASP-KISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
+P+ G+ P S K S + + + T PG P ++ + +
Sbjct: 952 KLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT--PGNLPVPSPMSPSSASISSFHG 1009
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE----VDGLLT-SE 590
++ + + G + PSS +S +I K G E E VD LT E
Sbjct: 1010 DES----DSISSPG--WPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFME 1063
Query: 591 PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIK-GEDKDEGP 649
GSPVSS D L C + G GL + ++K
Sbjct: 1064 ERGSPVSSLPAVGKKPLDLFRLYV-------------CVKEIG----GLAQVNKNKKWRE 1106
Query: 650 VAEQVKKSTLNPNAKEFNPT--KPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYS 707
+A + T + A + L + P P ST T Q L
Sbjct: 1107 LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD----TKKQPKLQP 1162
Query: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNS---VPGQQGKYRGAK---GSLPPQRSDQHQP 761
P + ++Q PQ SNS VPG A G + P + +
Sbjct: 1163 PSPAN-------SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSST 1215
Query: 762 ASA-PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQ- 819
S P + ++ P + TP + Y QQ P +M M + P++ F M +
Sbjct: 1216 ISVHDPFSDVSDSSFPKRNSMTPNAPY-----QQGMSMPDVMGRMPYEPNKDPFGGMRKV 1270
Query: 820 --SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPAT 877
S+ +T G P + + Q PS L Q +P+ A+ H+P
Sbjct: 1271 PGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN---LGMGQRQQFPYGASYDRRHEPYGQQ 1327
Query: 878 TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQS 937
P P Q P HQ G P QP + G GP A+ +
Sbjct: 1328 YPGQGPPSGQ---PPYGGHQPGLYPQ----QPNYKRHMDGMY---------GPPAKRHEG 1371
Query: 938 SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH-PPQS 996
Y+ Q++ + + G P P Q+ PPQ
Sbjct: 1372 DMYNMQ--YSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM 1429
Query: 997 HGGPPQGAV---PQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPG 1040
GGP Q + PQ + A A PYPY P QAP +PG
Sbjct: 1430 MGGPLQSSSSEGPQQNMWA--ARNDMPYPYQNRQGPGGPTQAPPYPG 1474
Score = 40.8 bits (94), Expect = 0.007
Identities = 135/617 (21%), Positives = 185/617 (29%), Gaps = 153/617 (24%)
Query: 533 LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583
LQ + +FQ ++ ++ Q + Q P NSL P P +++ G K+
Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633
++P G P+ SK D++D PP P G G +QPP P G
Sbjct: 108 AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164
Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
P EFN ++ P S GP + P
Sbjct: 165 GPAA-------------------------VPEFNN-------YYGSAAPASGGPGGRAGP 192
Query: 694 SIP----VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741
+ G ++S + M P + + YP N PG
Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252
Query: 742 -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS--YIPYNP 792
G G G A A AAAAAG SS Y +
Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312
Query: 793 QQFPGQPAMMQP---MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPT 849
+ G MM P A S+ R HP S +TP + +
Sbjct: 313 PRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTL-NQLLTS 367
Query: 850 PQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP 909
P + + SYP +++ A P SQPQSQ AA A +G G+
Sbjct: 368 PSPMMRSYGGSYPEYSS-------PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 910 Q--------------QNLYHPGALTGTP-PSL------PPGPSA--------------QS 934
Q HP GTP P++ P P
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 935 PQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH-------------- 979
PQ S P P Y Q+ P G A +Q PP +
Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
Query: 980 ------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGHP 1027
P PH PPQ L PQ + Q G P L+ P+ + +
Sbjct: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNLI 599
Query: 1028 QGEQPGQAPGFPGGADD 1044
Q E+P P G DD
Sbjct: 600 QQERPSSLPDLSGSIDD 616
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 380 PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438
PP P+H+ + P P S R + +RMSP L K P+ + + PPP
Sbjct: 1525 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1580
Query: 439 -PAVGR--MYPPRSPKSAAP 455
P + R +PP S +++ P
Sbjct: 1581 PPPIRREITFPPGSVEASQP 1600
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%)
Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54
Q QQ Q QQ P + GG P +GG A A PPGPP
Sbjct: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122
Query: 55 -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100
A P +G AG G L Q PP G AA+ GSA
Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
Query: 101 GQSTGKGPPQSPVFE 115
S G G P F+
Sbjct: 181 PASGGPGGRAGPCFD 195
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61
Q P PT + P G P + SA PP P AA + G
Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
AAAG GL + A P Q+R A G + G+ G P P+
Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463
Score = 30.8 bits (68), Expect = 7.3
Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 36 GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91
G G A P+ A+P L + + S + R G +P PPP Q +
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397
Query: 92 GAAAIGSARG 101
AAA G+A G
Sbjct: 398 QAAAAGAAAG 407
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 73.9 bits (180), Expect = 8e-13
Identities = 142/556 (25%), Positives = 194/556 (34%), Gaps = 114/556 (20%)
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
+ P G ++ LLTS SP+ ++ S E P AP P+ + G
Sbjct: 352 QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690
G KD G A+ S A++ + P +S P +PGP R+
Sbjct: 408 GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456
Query: 691 STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
+P P++ G + PQ S P GP PQ YP + PG
Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514
Query: 744 YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
+ + +PPQ S Q QP PP Q
Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557
Query: 787 YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844
Y+P QQ + Q M Q SQP AP ++ + L P SS P
Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612
Query: 845 AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
+ P AT+ + +T Q PA +P S HA+P G +P
Sbjct: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667
Query: 904 -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955
+GS Q + P ++ G+ P PPG +QS SS P A+ +P
Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719
Query: 956 GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002
GF N QTG + +P P PG + S G GP PQ
Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779
Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRR 1058
G + SGVP+ S S P P I + GQ P P GA +GR S
Sbjct: 780 GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA-----VPLGRMPSAGM 833
Query: 1059 QGLA-PGSVLCFPPSS 1073
Q PG++ PSS
Sbjct: 834 QNRPFPGNMSSMTPSS 849
Score = 54.7 bits (130), Expect = 5e-07
Identities = 166/786 (21%), Positives = 261/786 (33%), Gaps = 155/786 (19%)
Query: 331 QRQGSGRESPSLA--------SREGKYIPLPQRVREGPRGGVRCSSSRG----------G 372
Q SG P ++ SR Y +P GP G+ S++ G
Sbjct: 762 QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG 821
Query: 373 RPGLSSLPPRG----PHHLDNSSPGPGSEARGINGGPSRMSP------KAQRPLRGAKTL 422
L +P G P + SS P S GGP P KAQ A
Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAA-AAVMQ 880
Query: 423 SSPSNRPSGETSVPPPPAVGRMY---PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP 479
++ ++ S + S P G M P P + + + ++ P P S A
Sbjct: 881 AAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP--------PYSMAPAM 932
Query: 480 VTSSVSDPGVGSI-SPASPKISLA-PTDVKELSTKEPGRTLEPQELARIAG----KVPGL 533
V SS + G+ + SP K+ L D KE T +P + + G KV L
Sbjct: 933 VNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYEL 992
Query: 534 QNE-QKRFQLEELRKFGAQFKLQPSSSP---ENSLDPFPPRILKEEPKG-----KEKEVD 584
NE +++ ++ F + SS P + LD F + +E G K K+
Sbjct: 993 GNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWR 1052
Query: 585 GLLTSEPMGSPVSSKTE--------------SVSDKEDKPP-LAPSGGTEGPEQPPPPCP 629
L T+ +G+ S+ + + E+ PP + +G T+ + PP P
Sbjct: 1053 ELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSP 1112
Query: 630 S------------QTGSPPVGLIKGEDKDEGPVA---------EQVKKSTLNPNAKEFNP 668
+ TGS + + G+ K P + + + ST++ + F+
Sbjct: 1113 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVH-DPFSD 1171
Query: 669 TKPLLSVNKSTSTPTSPGPRTHSTPSI------------------------PVLTAGQ-- 702
+++ TP +P + S P + P +T GQ
Sbjct: 1172 VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMP 1231
Query: 703 ----SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQ 758
+Y+ + + MG Q P Y + GQQ +G PP
Sbjct: 1232 NSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGG-- 1289
Query: 759 HQPASAPPM----MQAAAAAGPPL------VAATPYSSYIPYNPQQFPGQ---PAMMQPM 805
HQP P GPP + YSS Q+ G P
Sbjct: 1290 HQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ 1349
Query: 806 AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHA 865
YP P +Q ++ T G PQ + Q S+E P A YP+
Sbjct: 1350 GQYP-YPYSRERMQGPGQIQTHGIPPQ--MMGGPLQSSSSEGPQQNMWAARNDMPYPYQN 1406
Query: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925
Q Q P ++ + H++ H+ QP Y + + P +
Sbjct: 1407 RQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQP----YMSSSASMQPIT 1462
Query: 926 LPPGPSAQSPQ------SSFPQPAAVY-AIHHQQLPHGFTNMAHVTQAHVQ----TGITA 974
PP PS Q+P S P PA+ ++ ++ P + + V T
Sbjct: 1463 RPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVT 1522
Query: 975 APPPHP 980
PPP P
Sbjct: 1523 GPPPQP 1528
Score = 53.1 bits (126), Expect = 1e-06
Identities = 165/720 (22%), Positives = 239/720 (33%), Gaps = 101/720 (14%)
Query: 353 PQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKA 412
PQ + GP+G + G P S P PG G A G P
Sbjct: 771 PQMSQYGPQGNYSRPPAYSGVPSASYSGP---------GPGMGISANNQMHGQGPSQPCG 821
Query: 413 QRPLRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAV 471
PL G + NRP G S P + G M P P P + + +AV
Sbjct: 822 AVPL-GRMPSAGMQNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMP-TVNRKAQEAAAAV 878
Query: 472 PTSSASIPVTSSVSDPGV---GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528
++A+ + S PG+ G ++ +SP ++T+ P ++ P + A
Sbjct: 879 MQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAA 938
Query: 529 KVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN------SLDPFPPRILKEEPKGKEKE 582
V GL + + + A K + + PE+ S +I K G E E
Sbjct: 939 SV-GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPE 997
Query: 583 ----VDGLLT-SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
VD LT E GSPVSS D L C + G
Sbjct: 998 RKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYV-------------CVKEIG---- 1040
Query: 638 GLIK-GEDKDEGPVAEQVKKSTLNPNAKEFNPT--KPLLSVNKSTSTPTSPGPRTHSTPS 694
GL + ++K +A + T + A + L + P P ST
Sbjct: 1041 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD 1100
Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNS---VPGQQGKYRGAK--- 748
T Q L P + ++Q PQ SNS VPG A
Sbjct: 1101 ----TKKQPKLQPPSPAN-------SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPH 1149
Query: 749 GSLPPQRSDQHQPASA-PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH 807
G + P + + S P + ++ P + TP + Y QQ P +M M +
Sbjct: 1150 GQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPY-----QQGMSMPDVMGRMPY 1204
Query: 808 YPSQPVFAPMLQ---SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864
P++ F M + S+ +T G P + + Q PS L Q +P+
Sbjct: 1205 EPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN---LGMGQRQQFPYG 1261
Query: 865 ATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPP 924
A+ H+P P P Q P HQ G P QP + G
Sbjct: 1262 ASYDRRHEPYGQQYPGQGPPSGQ---PPYGGHQPGLYPQ----QPNYKRHMDGMY----- 1309
Query: 925 SLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH 984
GP A+ + Y+ Q++ + + G P
Sbjct: 1310 ----GPPAKRHEGDMYNMQ--YSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1363
Query: 985 PPQVMLLH-PPQSHGGPPQGAV---PQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPG 1040
P Q+ PPQ GGP Q + PQ + A A PYPY P QAP +PG
Sbjct: 1364 PGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWA--ARNDMPYPYQNRQGPGGPTQAPPYPG 1421
Score = 40.8 bits (94), Expect = 0.007
Identities = 135/617 (21%), Positives = 185/617 (29%), Gaps = 153/617 (24%)
Query: 533 LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583
LQ + +FQ ++ ++ Q + Q P NSL P P +++ G K+
Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633
++P G P+ SK D++D PP P G G +QPP P G
Sbjct: 108 AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164
Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
P EFN ++ P S GP + P
Sbjct: 165 GPAA-------------------------VPEFNN-------YYGSAAPASGGPGGRAGP 192
Query: 694 SIP----VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741
+ G ++S + M P + + YP N PG
Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252
Query: 742 -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS--YIPYNP 792
G G G A A AAAAAG SS Y +
Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312
Query: 793 QQFPGQPAMMQP---MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPT 849
+ G MM P A S+ R HP S +TP + +
Sbjct: 313 PRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTL-NQLLTS 367
Query: 850 PQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP 909
P + + SYP +++ A P SQPQSQ AA A +G G+
Sbjct: 368 PSPMMRSYGGSYPEYSS-------PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 910 Q--------------QNLYHPGALTGTP-PSL------PPGPSA--------------QS 934
Q HP GTP P++ P P
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 935 PQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH-------------- 979
PQ S P P Y Q+ P G A +Q PP +
Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
Query: 980 ------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGHP 1027
P PH PPQ L PQ + Q G P L+ P+ + +
Sbjct: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNLI 599
Query: 1028 QGEQPGQAPGFPGGADD 1044
Q E+P P G DD
Sbjct: 600 QQERPSSLPDLSGSIDD 616
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 380 PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438
PP P+H+ + P P S R + +RMSP L K P+ + + PPP
Sbjct: 1472 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1527
Query: 439 -PAVGR--MYPPRSPKSAAP 455
P + R +PP S +++ P
Sbjct: 1528 PPPIRREITFPPGSVEASQP 1547
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%)
Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54
Q QQ Q QQ P + GG P +GG A A PPGPP
Sbjct: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122
Query: 55 -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100
A P +G AG G L Q PP G AA+ GSA
Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
Query: 101 GQSTGKGPPQSPVFE 115
S G G P F+
Sbjct: 181 PASGGPGGRAGPCFD 195
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61
Q P PT + P G P + SA PP P AA + G
Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
AAAG GL + A P Q+R A G + G+ G P P+
Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463
Score = 30.8 bits (68), Expect = 7.3
Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 36 GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91
G G A P+ A+P L + + S + R G +P PPP Q +
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397
Query: 92 GAAAIGSARG 101
AAA G+A G
Sbjct: 398 QAAAAGAAAG 407
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 73.2 bits (178), Expect = 1e-12
Identities = 112/434 (25%), Positives = 151/434 (34%), Gaps = 67/434 (15%)
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
+EQ+ + + K P P L +STP +P + +P P G Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482
Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
S PQ+ G + PQ YP + ++P + G+L Q A+ Q
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537
Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
+ + A PP P SSY YN Q PG +
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597
Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
H+ + F P NP + H Q + P P P P + S+
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648
Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
H+ H P A TP GS SQ A P P H PH +G
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705
Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
H + PP PP P S +S + A+HH Q P F + AH T +
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027
T PG H P H P GP PQG + +P +AS P+P + P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821
Query: 1028 QGEQ-PGQAPGFPG 1040
G Q P QA PG
Sbjct: 1822 HGVQGPQQASPVPG 1835
Score = 60.1 bits (144), Expect = 1e-08
Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
T PS S T PP +M P SP S PA P+P S V S A
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390
Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
+ + + + + + + A K T V+ S+++ + L P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449
Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
K ++ G+ ++ S SP+ P+ + P
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509
Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
++ G L T P G SS T S +++ S + P PPPP PS +
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560
Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
P + ++ +G +++Q T PN ++ +TS T PG H TP
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607
Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
L + ++ + +P P P + P S +SV G
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666
Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
+ Q + H P PP GP P+ P+ G A Q + +
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714
Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
P P S +L SG H + + P +PS+ PT P AT H +
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771
Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
H + H P P T P QPQ ++ P+P +G PH GS
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
+LP G Q PQ + P P + IH Q+P F N H + H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858
Score = 40.0 bits (92), Expect = 0.012
Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)
Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
PS G + Q + P G S P + P + HH ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778
Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
PS P P+ G P +P G S+P P A G + P A P +
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825
Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P+ +P A +P T + G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 73.2 bits (178), Expect = 1e-12
Identities = 112/434 (25%), Positives = 151/434 (34%), Gaps = 67/434 (15%)
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
+EQ+ + + K P P L +STP +P + +P P G Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482
Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
S PQ+ G + PQ YP + ++P + G+L Q A+ Q
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537
Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
+ + A PP P SSY YN Q PG +
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597
Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
H+ + F P NP + H Q + P P P P + S+
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648
Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
H+ H P A TP GS SQ A P P H PH +G
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705
Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
H + PP PP P S +S + A+HH Q P F + AH T +
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027
T PG H P H P GP PQG + +P +AS P+P + P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821
Query: 1028 QGEQ-PGQAPGFPG 1040
G Q P QA PG
Sbjct: 1822 HGVQGPQQASPVPG 1835
Score = 60.1 bits (144), Expect = 1e-08
Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
T PS S T PP +M P SP S PA P+P S V S A
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390
Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
+ + + + + + + A K T V+ S+++ + L P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449
Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
K ++ G+ ++ S SP+ P+ + P
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509
Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
++ G L T P G SS T S +++ S + P PPPP PS +
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560
Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
P + ++ +G +++Q T PN ++ +TS T PG H TP
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607
Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
L + ++ + +P P P + P S +SV G
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666
Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
+ Q + H P PP GP P+ P+ G A Q + +
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714
Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
P P S +L SG H + + P +PS+ PT P AT H +
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771
Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
H + H P P T P QPQ ++ P+P +G PH GS
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
+LP G Q PQ + P P + IH Q+P F N H + H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858
Score = 40.0 bits (92), Expect = 0.012
Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)
Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
PS G + Q + P G S P + P + HH ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778
Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
PS P P+ G P +P G S+P P A G + P A P +
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825
Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P+ +P A +P T + G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 73.2 bits (178), Expect = 1e-12
Identities = 113/438 (25%), Positives = 150/438 (34%), Gaps = 55/438 (12%)
Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
P PPP P TG G+ G + + T P P PL V
Sbjct: 708 PVLPPPSTPMPTGP-------GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----- 755
Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAP-QMYPYPVSNSV 737
P +P A S + +P + +PQ + P Q P QM P PV +
Sbjct: 756 -----------PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804
Query: 738 PGQQGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
G LPP D P PP + A P L A P +S P P Q
Sbjct: 805 TPLAGI-----DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQ 857
Query: 795 F------PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS-SSTPQYPSAEQ 847
PG P M P+ P P+L P + + S A+ P YP+A
Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA-- 915
Query: 848 PTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906
PQ V S PHH Q + A PQPA P + P P P P +
Sbjct: 916 -FPQMAPTDVPPS-PHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973
Query: 907 GQPQQNLYHPGALTGTPPSLPPGPS----AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAH 962
+P Q + P + P LPP P+ + Q P+ AA A Q+ G +
Sbjct: 974 -RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APY 1031
Query: 963 VTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQG-AVPQSGVPALSASTPSPY 1021
Q PP +P P+V+L P+ P A + V ++ T +
Sbjct: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLL 1091
Query: 1022 PYIGHPQGEQPGQAPGFP 1039
P P PG A P
Sbjct: 1092 PPANPPLPGGPGIASPCP 1109
Score = 46.6 bits (109), Expect = 1e-04
Identities = 77/281 (27%), Positives = 92/281 (32%), Gaps = 46/281 (16%)
Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQH--------AAP 891
P+ P A+Q L T+ S A+ Q +T + SQ Q AAP
Sbjct: 589 PEEPEADQ---HLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP 645
Query: 892 SPVQ----HQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQ-SPQSSFPQPAAV 945
SP Q + P L P Y P A G P P P+ S Q FP PA
Sbjct: 646 SPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705
Query: 946 YAIHHQQLPHGFTNM----AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPP 1001
+A LP T M Q A P P P P V+ L P H P
Sbjct: 706 FA---PVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPY 762
Query: 1002 QGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGL 1061
Q G PA P + P + P Q P P L + GL
Sbjct: 763 LAPASQVGAPAQLKPLQMPQAPL-QPLAQVPPQMPPIPVVPPITPLAGI--------DGL 813
Query: 1062 APG-------------SVLCFPPSSLSCDPAAPLPTASPAL 1089
P F P+ + AAPLP ASPAL
Sbjct: 814 PPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL 854
Score = 46.6 bits (109), Expect = 1e-04
Identities = 74/270 (27%), Positives = 88/270 (32%), Gaps = 42/270 (15%)
Query: 770 AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 829
A AA P +P S P PQ P A QP A P PV + + P L
Sbjct: 641 ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA-APGLPVGSVPAPACPPSLQQHF 699
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
A+ + PS PT A Q QP P PT P Q
Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQ------------QPPPLAQPT---PLPQVL 744
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIH 949
AP PV PHL P + G P L P Q+P QP A
Sbjct: 745 APQPVVPLQPVPPHL------PPYLAPASQVGAPAQLKPLQMPQAPL----QPLA----- 789
Query: 950 HQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG 1009
Q+P + V GI PP P P PP PPQ P
Sbjct: 790 --QVPPQMPPIPVVPPITPLAGIDGLPPALPDLP-----TATVPPVP---PPQYFSPAVI 839
Query: 1010 VPALSASTPSPYPYIGHPQGEQPGQAPGFP 1039
+P+L+A P P + + P PG P
Sbjct: 840 LPSLAAPLPPASPALPLQAVKLP-HPPGAP 868
Score = 45.4 bits (106), Expect = 3e-04
Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%)
Query: 352 LPQRVREGPRG----GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR 407
+P + E RG G+ ++ RPG R D P PG EA G P
Sbjct: 10 VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-PGLEAAEAPG-PQP 67
Query: 408 MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA-VGRMYPPRSPKSAAPAPISASCPEP- 465
P +R L KT + R G + P P A V + P +P A P P+ P P
Sbjct: 68 PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPD 127
Query: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTL--EPQE 522
PI +AV T+ A P G A+ + E + EPGRT EP+E
Sbjct: 128 PIAAAVETAPA----------PDGGPREEAAATVRKEDEGAAE-AKPEPGRTRRDEPEE 175
Score = 42.0 bits (97), Expect = 0.003
Identities = 179/825 (21%), Positives = 273/825 (33%), Gaps = 171/825 (20%)
Query: 1 MLKPQPL--QQPSQPQQPPPTQQAVARRPPGGTSPPNG---GLPGPLATSAAP-----PG 50
ML PQP+ QP+ P +P P Q + + +P + G P P A A P
Sbjct: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044
Query: 51 PPAA------------ASPCLGP--------VAAAGSGLRRGAEGILAPQPPPPQQHQER 90
PPAA A+P L P V+A+ + +L P PP
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------L 1098
Query: 91 PGAAAIGSA------------RGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVK 138
PG I S Q++ PP P Y S + + +C+
Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS--GKELSDSCE-- 1154
Query: 139 VKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRE-----DIVDTMV---FKPSDV 190
G G + +++ R E A PR + D MV + +
Sbjct: 1155 ---GAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNH 1211
Query: 191 MLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNG 250
+V F+ D + D+ + + + E + + Q + D D ++D G
Sbjct: 1212 KMVTFK-FDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRG 1270
Query: 251 WDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREI-----ES 305
DP + G+ T +S S P+ + N +R +A ES
Sbjct: 1271 SDPGTSPP-HLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329
Query: 306 SPQYRLRIAMENDDGRTEEEKHSAVQR-QGSGRESPS-LASREGKYIPLPQRVREGPRGG 363
SP L E + SA + Q S +E PS LAS++ P P
Sbjct: 1330 SPPLPLSSLPP------EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383
Query: 364 VRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGP------------------ 405
+ SS P +++LP G ++ P P S GGP
Sbjct: 1384 LAPSS-----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438
Query: 406 SRMSPKAQRPLRG--AKTLSSPSNRPSGETSVP----PPPAVGRMYPPRSPKSAAPAPI- 458
+ +P A +PL A +P + + S P PPPA P SP S P P
Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPAL 1493
Query: 459 -----------------SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
++ P PP+G VP S + P P++
Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP---------PRVGF 1544
Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE--QKRFQLEELRKFGAQFKLQPSSS 559
+ +K L K RTL QE + G E + F LE LR G Q + +
Sbjct: 1545 VDSTIKSLDEKL--RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR--GDQPRSEVCGG 1600
Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619
+ +L P P + + + V+ + G+ + T S E P +
Sbjct: 1601 -DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRD 1659
Query: 620 GPE--QPPPPCPSQTGSPPV----GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
G + PS P ++ D+D G E S+ P P +
Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE----SSAEP------PPSDMG 1709
Query: 674 SVNKSTSTPTSPGPRTHSTP---------SIPVLTAGQSGLYSPQ 709
+V S P + G R +P S P T G+ + S Q
Sbjct: 1710 TVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ 1754
Score = 37.7 bits (86), Expect = 0.060
Identities = 67/244 (27%), Positives = 87/244 (35%), Gaps = 60/244 (24%)
Query: 721 PAVQAPQMYP-YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV 779
PA +AP+ P P+S SLPP+ S SAP Q ++ P +
Sbjct: 1322 PAPEAPESSPPLPLS---------------SLPPEASQD----SAPYKDQLSSKEQPSFL 1362
Query: 780 AATPYSSYI-PYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSS 838
A+ S P NP PG P P+A PS P + Q TS A ++S
Sbjct: 1363 ASQQLLSQAGPSNP---PGAPPA--PLA--PSSPPVTALPQDGAAPATSTMPEPASGTAS 1415
Query: 839 TPQYPSAEQPTPQALYATVHQSYP---HHATQLHAHQ-----------PQPATTPTGSQP 884
P TPQ L + + S P H L P+ A+T S P
Sbjct: 1416 QAGGPG----TPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP 1471
Query: 885 QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGAL------TGTPPSLPPGPSAQSPQSS 938
+ P+P P GQP L P A+ T PS P GP+
Sbjct: 1472 REPLPPPAPEPSPHSGTPQPALGQPAPLL--PAAVGAVSLATSQLPSPPLGPTVP----- 1524
Query: 939 FPQP 942
PQP
Sbjct: 1525 -PQP 1527
Score = 35.8 bits (81), Expect = 0.23
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%)
Query: 376 LSSLPPRGPHHLDNSSP-GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP-SGET 433
L +PP P +L +S G ++ + + + + P AQ P + P P +G
Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811
Query: 434 SVPP-----PPAVGRMYPPRSPKSAAPAPI--SASCPEPPIGSAVPTSSASIPVTSSVSD 486
+PP P A PP P+ +PA I S + P PP A+P + +P
Sbjct: 812 GLPPALPDLPTATVPPVPP--PQYFSPAVILPSLAAPLPPASPALPLQAVKLP-----HP 864
Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPG 515
PG P + AP + L+ PG
Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPG 893
Score = 35.8 bits (81), Expect = 0.23
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 38/212 (17%)
Query: 910 QQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQ---- 965
QQN+ H G + P+ ++P+SS P P + Q + + +
Sbjct: 1302 QQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF 1361
Query: 966 -AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYI 1024
A Q A P PGAP P P S PP A+PQ G +++ P P
Sbjct: 1362 LASQQLLSQAGPSNPPGAPPAPLA-----PSS---PPVTALPQDGAAPATSTMPEPASGT 1413
Query: 1025 GHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRR----QGLAPGSVLCFP-PSSLS---- 1075
G PG P G + + + Q L G C P P + S
Sbjct: 1414 ASQAG-----GPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDA 1468
Query: 1076 CDPAAPLP-----------TASPALSDPDCLL 1096
P PLP T PAL P LL
Sbjct: 1469 SAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 12 QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAA-----SPCLGPVAAAG 66
+P P P A+ +P +P + G P P+ T P P AAA +P GP A
Sbjct: 92 RPAAPAPA--ALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
Query: 67 SGLRRGAEGILAPQPPPPQQHQERP 91
+ +R+ EG +P P + ++ P
Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEP 173
Score = 33.1 bits (74), Expect = 1.5
Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 50/249 (20%)
Query: 315 MENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGG-VRCSSSRGGR 373
ME + + S G R+ +AS +PQ V R V + GG
Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433
G SS P P S+ + G S GA+ L SP RP +
Sbjct: 1696 AGESSAEP------------PPSDMGTVGGQASHPQTL------GARALGSPRKRPEQQD 1737
Query: 434 SVPPPPAVGR-----------MYPPRSPKSAAPAPI----SASCPEPPIGSAVPTSSASI 478
P VGR + P S + +AP + + S P+ + +++SI
Sbjct: 1738 VSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSI 1797
Query: 479 ------PVTSSVSDPGVGSISPASPKISL------APTDVKELST--KEPGR--TLEPQE 522
PV+S D G + P + SL A VK+ + + P R +L P+
Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857
Query: 523 LARIAGKVP 531
+R+ KVP
Sbjct: 1858 PSRVGMKVP 1866
Score = 32.0 bits (71), Expect = 3.3
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 31/200 (15%)
Query: 622 EQPPPPCPSQTGSPPVGLIKGE-DKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
E P P P + P+ + E +D P +Q+ F ++ LLS ++
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK----EQPSFLASQQLLSQAGPSN 1375
Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA-----PQMYPYPVSN 735
P +P P + S PV Q G + S +P+ G A QA PQ +
Sbjct: 1376 PPGAP-PAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432
Query: 736 SVP---------GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
S P Q G P + + ASAP PP +P+S
Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP-----REPLPPPAPEPSPHSG 1487
Query: 787 YIPYNPQQFPGQPAMMQPMA 806
PQ GQPA + P A
Sbjct: 1488 ----TPQPALGQPAPLLPAA 1503
Score = 31.6 bits (70), Expect = 4.3
Identities = 20/56 (35%), Positives = 20/56 (35%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
L PQP P P PT PP T PP LP P PP A P
Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999
Score = 30.8 bits (68), Expect = 7.3
Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P SP P A + P +P PP P R+ APA I
Sbjct: 831 PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI------ 884
Query: 465 PPIGSAVPTSSASIPVTSSVSD-PGVGSISPASPKISLAPTDV 506
P+ + P A++ + S+V+ PG A P+ +APTDV
Sbjct: 885 -PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ--MAPTDV 924
Score = 30.4 bits (67), Expect = 9.6
Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%)
Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
P P T Q + PP PP LP PP P P L P R
Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLP---PQPVLPPQPTLPPQPVLPPQPT------RP 975
Query: 73 AEGILAPQPPPPQQ 86
+ +L PQP P Q
Sbjct: 976 PQPVLPPQPMLPPQ 989
Score = 30.4 bits (67), Expect = 9.6
Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 16/76 (21%)
Query: 10 PSQPQQPP-PTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
P QP PP PT PP T PP LP P T PP P P L P
Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLP-PQPT--RPPQPVLPPQPMLPP------- 988
Query: 69 LRRGAEGILAPQPPPP 84
+ +L PQP P
Sbjct: 989 -----QPVLPPQPALP 999
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 73.2 bits (178), Expect = 1e-12
Identities = 131/515 (25%), Positives = 172/515 (33%), Gaps = 82/515 (15%)
Query: 593 GSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652
G P S E S + P LA GG P + P PS S P L +G P
Sbjct: 159 GGPGSLPPEPPSVSQAFPTLAGPGGLF-PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPP 217
Query: 653 QVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP-SIPVLTAGQSGLYSPQYI 711
++ NA +N L S + + P P S+P S P L L P
Sbjct: 218 PA----ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPP-- 271
Query: 712 SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771
+P + PA P P PVS++ G G P P A ++ AA
Sbjct: 272 --LPPSNNLPAHPGPASQP-PVSSATM-HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAA 327
Query: 772 AAAG-PPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPML----------QS 820
A A PPL + P + ++P P +P L +S
Sbjct: 328 AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRS 387
Query: 821 NPRMLTSGSHPQAIVSSSTPQYPSAEQ----PTPQALYATVHQSYPHHATQLHAHQPQPA 876
PR P ++ S P PS PTP H + AH P P
Sbjct: 388 RPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTP----GPSHSDGSFNLLGSDAHLPPPP 443
Query: 877 TTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQ 936
T +GS PQ +H P+Q P L PG +G+ S+P P+ +
Sbjct: 444 TLSSGSPPQPRH----PIQ------PSL-----------PGTTSGSLSSVPGAPAPPAAS 482
Query: 937 SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP-------GAPHPPQVM 989
+ P+ V + L G + G A P P P GA P +
Sbjct: 483 KAPVVPSPVLQSPSEGLGMGAGPACPLPPL---AGGEAFPFPSPEQGLALSGAGFPGMLG 539
Query: 990 LLHPPQSHGGPPQGAVPQS---GVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRI 1046
L P S G PP + GV P P P + P G P APG P G
Sbjct: 540 ALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEG----- 594
Query: 1047 LCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAP 1081
L S+L PPS L P+AP
Sbjct: 595 ------------PSLLVASLLPPPPSDLLPPPSAP 617
Score = 71.6 bits (174), Expect = 4e-12
Identities = 180/800 (22%), Positives = 257/800 (32%), Gaps = 179/800 (22%)
Query: 384 PHHLDNSSPGPGSE--------ARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSV 435
P SPGP S +NGGP + P+ + TL+ P +
Sbjct: 132 PQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA- 190
Query: 436 PPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA 495
P P+ G P P+ AP+P A P P I P+ + + SS+ +GS P
Sbjct: 191 DPVPSGGSSSPRFLPRGNAPSP--APPPPPAISLNAPSYNWGAALRSSLVPSDLGS--PP 246
Query: 496 SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
+P S +P L T P + PG
Sbjct: 247 APHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPG----------------------P 284
Query: 556 PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP--VSSKTESVSDKEDKPPLA 613
S P +S P +L P G G T E G+P ++S S + K PPL
Sbjct: 285 ASQPPVSSATMHLPLVLG--PLG------GAPTVEGPGAPPFLASSLLSAAAKAQHPPLP 336
Query: 614 PSGGTEG----------------------PEQPPPPCPSQTGSPPVGLIKGEDKDEGPV- 650
P +G P +PP G P + + PV
Sbjct: 337 PPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVP 396
Query: 651 --------AEQVKKSTLN------PNAKEFNPTKPLLSVNKSTSTPTS------PGPRTH 690
++ + S L+ P + + LL + P + P PR
Sbjct: 397 QPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHP 456
Query: 691 STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750
PS+P T+G +S +P PA + P PV S G G
Sbjct: 457 IQPSLPGTTSGS--------LSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP 508
Query: 751 LPPQRSDQHQPASAPPMMQAAAAAG-PPLVAATPYSSYIPYNPQQFPGQPAMMQPM---- 805
LPP + P +P A + AG P ++ A P +P + Q P P + +
Sbjct: 509 LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALP----LPLSLGQPPPSPLLNHSLFGVL 564
Query: 806 ----AHYPSQPVFAPMLQSNPRMLTSGSH-PQAIVSSSTPQYPSAEQPTPQALYATVHQS 860
P +P+ P P + P +V+S P PS P P A + + S
Sbjct: 565 TGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLAS 624
Query: 861 YPHHATQLHAHQPQPATTPT-GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGAL 919
+ P A PT G S A P SG+P L L
Sbjct: 625 F----------LPLLALGPTAGDGEGSAEGAGGP------------SGEPFSGLGDLSPL 662
Query: 920 TGTPPSLPP----------GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQ 969
P S PP + P + PQP + A P + VT A
Sbjct: 663 LFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSA------PQPGPPTSSVTTATTD 716
Query: 970 TGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQG 1029
G ++ + PPQ++ P GA + +L+ S+P P + P G
Sbjct: 717 PGASSLGKAPSNSGRPPQLL---------SPLLGASLLGDLSSLT-SSPGALPSLLQPPG 766
Query: 1030 EQPGQAPG---FPGG--------ADDRILCRVGRSHSRRRQGLAPGSVLCFPP----SSL 1074
G PGG A + C + Q AP C PP S+L
Sbjct: 767 PLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAP----CLPPESPASAL 822
Query: 1075 SCDPA-APLPTASPALSDPD 1093
+PA PL +P PD
Sbjct: 823 EPEPARPPLSALAPPHGSPD 842
Score = 44.7 bits (104), Expect = 5e-04
Identities = 162/724 (22%), Positives = 223/724 (30%), Gaps = 163/724 (22%)
Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRG 418
GP GG G P L+S + P S +G P+AQ P
Sbjct: 302 GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQG-------RRPRAQAPSAS 354
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+ PS R PP V R+ R P++ + A P P
Sbjct: 355 HSSSLRPSQRRPRR-----PPTVFRLLEGRGPQTPRRSRPRAPAPVP------------- 396
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538
+ S EP + + P L+ + PG +
Sbjct: 397 ----------------------------QPFSLPEPSQPILPSVLSLLGLPTPGPSHSDG 428
Query: 539 RFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEP--MGSPV 596
F L G+ L P + + P P ++ G G L+S P P
Sbjct: 429 SFNL-----LGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG---TTSGSLSSVPGAPAPPA 480
Query: 597 SSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656
+SK V + P G GP P PP + G + P EQ
Sbjct: 481 ASKAPVVPSPVLQSPSEGLGMGAGPACPLPP------------LAGGEAFPFPSPEQ--- 525
Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQ 716
L + F L + S P HS VLT G G P+
Sbjct: 526 -GLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSL--FGVLTGG-GGQPPPE------- 574
Query: 717 IHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP 776
P + P P++ P +G LPP SD P SAPP A+
Sbjct: 575 ----PLLPPPGGPGPPLAPGEP--EGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFL-- 626
Query: 777 PLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS 836
PL+A P + G A PS F+ + +P + S P +++
Sbjct: 627 PLLALGPTA-----------GDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIA 675
Query: 837 SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQH 896
++ + P P L A QP P T+ + A P
Sbjct: 676 LNSALLAATLDPP---------SGTPPQPCVLSAPQPGPPTSSVTT------ATTDPGAS 720
Query: 897 QAGQAPHLGSGQPQQNLYHP---GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQL 953
G+AP SG+P Q L P +L G SL P A P P + Q L
Sbjct: 721 SLGKAPS-NSGRPPQ-LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLL 778
Query: 954 PHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH---PPQSHGGP------PQGA 1004
P G APPP A P +L PP+ P P A
Sbjct: 779 PGG-----------------GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASA 821
Query: 1005 V-PQSGVPALSASTP---SPYPYI-----GHPQGEQPGQAPGFPGGADDRILCRVGRSHS 1055
+ P+ P LSA P SP P + G G++ + G G + GR
Sbjct: 822 LEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPG 881
Query: 1056 RRRQ 1059
RR+
Sbjct: 882 SRRE 885
Score = 41.6 bits (96), Expect = 0.004
Identities = 59/266 (22%), Positives = 95/266 (35%), Gaps = 59/266 (22%)
Query: 373 RPGLSSLPPRGP--HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTL---SSPSN 427
+P + S P GP + ++ PG+ + G S P+ PL GA L SS ++
Sbjct: 694 QPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTS 753
Query: 428 RPSGETSVPPPPAV---GRMYPPRSPKSAAPAPISASC-------------PEPPIGSAV 471
P S+ PP G++ P AP P+S + PE P +
Sbjct: 754 SPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCL 813
Query: 472 PTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELST-------------------- 511
P S P ++ +P +S +P V EL T
Sbjct: 814 PPES---PASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGING 870
Query: 512 -------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLE--------ELRKFGAQFKLQP 556
++PG EP LA G G + +R EL + GA+ K P
Sbjct: 871 EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPP 930
Query: 557 SSSPENSLDPFPPRILKEEPKGKEKE 582
P + PP ++++ +G+ ++
Sbjct: 931 PPGPHSEDLKVPPGVVRKSRRGRRRK 956
Score = 38.9 bits (89), Expect = 0.027
Identities = 36/126 (28%), Positives = 41/126 (32%), Gaps = 9/126 (7%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVA 63
P PL P P GG PP P PL PGPP A GP
Sbjct: 542 PLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP----PEPLLPPPGGPGPPLAPGEPEGPSL 597
Query: 64 AAGSGLRRGAEGILAPQPPPPQQ--HQERPGAA---AIGSARGQSTGKGPPQSPVFEGVY 118
S L +L P PP P A G G + G G P F G+
Sbjct: 598 LVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLG 657
Query: 119 NNSRML 124
+ S +L
Sbjct: 658 DLSPLL 663
Score = 37.0 bits (84), Expect = 0.10
Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 17/115 (14%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPP------------GP 51
P P S P PP + A PP PP+ LP ++ PP GP
Sbjct: 246 PAPHASSSPPSDPPLFHCSDALTPP--PLPPSNNLPAHPGPASQPPVSSATMHLPLVLGP 303
Query: 52 PAAASPCLGPVAA---AGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
A GP A A S L A+ P PPP RP A A ++ S
Sbjct: 304 LGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSS 358
Score = 34.3 bits (77), Expect = 0.66
Identities = 40/158 (25%), Positives = 57/158 (36%), Gaps = 25/158 (15%)
Query: 881 GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFP 940
G+ PQ H +P S +P + L G P SLPP P + S +FP
Sbjct: 129 GASPQMFHTV----------SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS--QAFP 176
Query: 941 QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP 1000
A + +L + + + G +P P P PP + L P + G
Sbjct: 177 TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAP----PPPPAISLNAPSYNWG-- 230
Query: 1001 PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGF 1038
A+ S VP+ S P+P H P P F
Sbjct: 231 --AALRSSLVPSDLGSPPAP-----HASSSPPSDPPLF 261
Score = 32.0 bits (71), Expect = 3.3
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 6/56 (10%)
Query: 31 TSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ 86
+SP G P T + PGPP+A PC P G G L P+PP Q
Sbjct: 124 SSPGEGASPQMFHTVS--PGPPSARPPCRVPPTTP----LNGGPGSLPPEPPSVSQ 173
Score = 32.0 bits (71), Expect = 3.3
Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Query: 11 SQPQQPPPTQQAVARRP-PGGTSP-------PNGG------LPGPLATSAAPPGPPAAAS 56
S P +PP QA PGG P P+GG LP A S APP PPA +
Sbjct: 163 SLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAIS- 221
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
P G+ LR PP P P
Sbjct: 222 -LNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPP 255
Score = 31.6 bits (70), Expect = 4.3
Identities = 32/117 (27%), Positives = 40/117 (34%), Gaps = 24/117 (20%)
Query: 13 PQQPPPTQQAVARRPPGGT-SPPNGGLPGPLATSAAPPGPP------AAASPCLGPVAAA 65
P PPT A+ T PP+G P P SA PGPP A P + A
Sbjct: 666 PLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKA 725
Query: 66 GSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG------PPQSPVFEG 116
S R PPQ GA+ +G ++ G P P+ G
Sbjct: 726 PSNSGR-----------PPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSG 771
Score = 30.8 bits (68), Expect = 7.3
Identities = 49/206 (23%), Positives = 69/206 (33%), Gaps = 40/206 (19%)
Query: 320 GRTEEEKHSAVQRQGSGRESPSLASREGKYIP--------LPQRVREGPRGGVRCSSSRG 371
G + +H +Q G S SL+S G P +P V + P G+ G
Sbjct: 448 GSPPQPRHP-IQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGL----GMG 502
Query: 372 GRPGLSSLPPRGPHHLDNSSPGPGSEARG-------------INGGPSRMSPKAQRPLRG 418
P P G SP G G ++ G SP L G
Sbjct: 503 AGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFG 562
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
L+ +P E +PPP G P P+ P+ + AS PP +P SA
Sbjct: 563 V--LTGGGGQPPPEPLLPPPGGPGPPLAPGEPE--GPSLLVASLLPPPPSDLLPPPSA-- 616
Query: 479 PVTSSVSDPGVGSISPASPKISLAPT 504
P ++ P ++L PT
Sbjct: 617 --------PPSNLLASFLPLLALGPT 634
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 72.0 bits (175), Expect = 3e-12
Identities = 167/711 (23%), Positives = 236/711 (33%), Gaps = 113/711 (15%)
Query: 305 SSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGV 364
SSPQ R R + D + + + GS S + + + V P+GG
Sbjct: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGG- 458
Query: 365 RCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSS 424
S RG G S+ +S + G G S K +RP + S
Sbjct: 459 ---SGRGSPSGGSTA---------EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506
Query: 425 PSNR----PSGETSVPPPPAVGRMYPPRSPK----SAAPAPISASCPEPPIGSAVPTSSA 476
R P G +PP P R P+ P+ + +A CP P S VP S
Sbjct: 507 LHQRGLAVPDGPLGLPPKPE--RKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS- 563
Query: 477 SIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE 536
PG P SP+ +L+P+ + P TL P+ LA PG
Sbjct: 564 ----------PGGSRRPPRSPERTLSPSSGYSSQSGTP--TLPPKGLAGPPAS-PGKAQP 610
Query: 537 QKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-----PRIL------------------- 572
K ++ LR GA +S +S DP P P+IL
Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670
Query: 573 ---KEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQP 624
+P+ L + PVS+ T++ P PL S + P
Sbjct: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSP 729
Query: 625 PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL-NPNAKEFNPTKPLLSVNKSTSTPT 683
PP P PP K E E P A + + L +PN + P P + S
Sbjct: 730 PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN---WPPPPPPAPEEQDLSMAD 786
Query: 684 SPGPRTHSTPSIPVLTAGQSGLYSPQYIS---------YIPQIHMGPAVQAPQMYPYPV- 733
P P AG SG SP+ +S QI + P P P
Sbjct: 787 FPPPEEAFFSVASPEPAGPSG--SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844
Query: 734 SNSVPGQQGKYRG------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
++S PG K +KG PP R D P P ++Q P +
Sbjct: 845 ASSAPGHVAKLPQKEPVGCSKGGGPP-REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903
Query: 788 IPYNPQQFPGQPAMMQPMAHYPSQPVFAPM--LQSNPRMLTSGSHPQAIVSSSTPQ-YPS 844
P PQ+ P + A+ + PV AP L + R+ +SS+ P P
Sbjct: 904 GPSAPQK-PLRRALSG-----RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957
Query: 845 AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
AE PQ+ +T + + +L +P T Q S + + QAP
Sbjct: 958 AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017
Query: 905 GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955
P P G PP P S+P+ + A LPH
Sbjct: 1018 SPKAPPPVARKPS--VGVPPPASP---------SYPRAEPLTAPPTNGLPH 1057
Score = 53.9 bits (128), Expect = 8e-07
Identities = 155/651 (23%), Positives = 212/651 (32%), Gaps = 138/651 (21%)
Query: 467 IGSAVPTSSASIPVTSSVSDPGV----GSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
+G + T + + S++ PG+ G P SP +S++P LS P L P
Sbjct: 306 VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISP-QATYLSKLIPHAVLPPTV 364
Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582
G+ LR S + SL F + +P+ +
Sbjct: 365 DVVALGRC-------------SLRTLSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPS 410
Query: 583 VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-PEQ--------PPPPCPSQTG 633
+S S S VSD L+ GG+EG PE PPP S G
Sbjct: 411 -----SSSDTWSHSQSSDTIVSDGST---LSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462
Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
SP G AE ++ + + + L + + P P RTHS
Sbjct: 463 SP----------SGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR----PPPPPRRTHSLH 508
Query: 694 SIPVLTA-GQSGLYSPQYISYIPQIHMGPAVQ------APQMYPYPVSNSVPGQQGKYRG 746
+ G GL PQ+ P A P P ++ VPG
Sbjct: 509 QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS----- 563
Query: 747 AKGSLPPQRSDQ--------HQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQF--- 795
GS P RS + + S P + AGPP A+P + P P++
Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPP-KPERVTSL 619
Query: 796 --PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS-------GSHPQAIVS-SSTPQYPSA 845
PG + S AP +S P++LT HP+ S P P +
Sbjct: 620 RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679
Query: 846 EQPTPQALYATV------------HQSYPHHATQLHAHQPQPATT----PTGSQPQSQHA 889
P AL A QS P T L Q P + P S P S H
Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739
Query: 890 APSPVQHQ--AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS-PQSSFPQPAAVY 946
P P + +AP S ++ L P PP PP P Q + FP P +
Sbjct: 740 PPPPTKKPEVVVEAPS-ASETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF 794
Query: 947 AIHHQQLPHG-----------FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP-- 993
P G + + T +Q + PPP P AP P H
Sbjct: 795 FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854
Query: 994 -PQSH-------GGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036
PQ GGPP+ V G P + TPS + PG AP
Sbjct: 855 LPQKEPVGCSKGGGPPREDV---GAPLV---TPSLLQMVRLRSVGAPGGAP 899
Score = 38.9 bits (89), Expect = 0.027
Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)
Query: 5 QPLQQPSQPQQPPPTQQ----AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
+PLQ P+ P PPP + ++A PP + + P P S + P +SP
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS---PELVSSPAAS 818
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR---GQSTGKGPPQSPV 113
+A ++ P PP P PG A + G S G GPP+ V
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874
Score = 35.0 bits (79), Expect = 0.39
Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 10/117 (8%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPG--PLATSAAPPGPPAAASPCLG 60
KP+ QQP P+ P A P +P N +PG P + P P SP G
Sbjct: 524 KPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG 583
Query: 61 PVAAAGS------GLRRGAEGILAPQPPPPQQ--HQERPGAAAIGSARGQSTGKGPP 109
+ +G+ GL QPP P++ PGA+ S + P
Sbjct: 584 YSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640
Score = 32.7 bits (73), Expect = 1.9
Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 17/114 (14%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAA----PPGPPAAASPCL-GPVAA 64
PS+P+ P P A+A +PGP++T+ A PP P +P PV +
Sbjct: 674 PSKPRSPNPAAPALAAPAV---------VPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724
Query: 65 AGSGLRRGAEGILAPQPPP---PQQHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
P PPP P+ E P A+ Q PP P E
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778
Score = 30.8 bits (68), Expect = 7.3
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 33 PPNGGLPGPLATSAAPPGPPAAASPCL-GPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
PP+ +P P + + P P A+P L P G A +PQ PP Q P
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA----SPQSPPTPQTTLTP 716
Query: 92 GAAAIGSARGQSTGKGPPQS 111
+ ++ QS PP S
Sbjct: 717 LQESPVISKDQSPPPSPPPS 736
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 71.6 bits (174), Expect = 4e-12
Identities = 105/374 (28%), Positives = 131/374 (35%), Gaps = 61/374 (16%)
Query: 683 TSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQG 742
T PGP S P P +G + L P+ P H P P +YP P G
Sbjct: 780 TGPGPHYLSGPLPPGTYSGPTQLIQPR----APGPHAMPVAPGPALYPAPAYTPELG--- 832
Query: 743 KYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATPYSSYIPYNPQQFPG-QPA 800
L P+ S QH S+P + GP P VA P + P QF G + A
Sbjct: 833 --------LVPRSSPQHGVVSSPYV-----GVGPAPPVAGLPSAP-----PPQFSGPELA 874
Query: 801 MMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
M A + AP+ + PR + + P PQ PTP A Q
Sbjct: 875 MAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQ----PLPTPYTYPAGAKQ 930
Query: 860 SYP---HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 916
P H ++ + A P P P QPQ H P P Q Q P +L+ P
Sbjct: 931 PIPAQHHFSSGIPAGFPAPRIGP---QPQP-HPQPHPSQAFGPQPPQQPLPLQHPHLFPP 986
Query: 917 GALTGTPPSLPPGPSAQSPQSSFPQPAAVYA----IHHQQLPHGFTNMAHVTQAHVQTGI 972
A P LPP QSP PQP + +H Q P Q +
Sbjct: 987 QA----PGLLPP----QSPYPYAPQPGVLGQPPPPLHTQLYPGP-------AQDPLPAHS 1031
Query: 973 TAAPPPHPGA---PHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQG 1029
A P P PG PHPP P GP + G + STPSP+
Sbjct: 1032 GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPS 1091
Query: 1030 EQPGQAPGFPGGAD 1043
PG P P A+
Sbjct: 1092 PGPGPVPPRPPAAE 1105
Score = 56.6 bits (135), Expect = 1e-07
Identities = 93/372 (25%), Positives = 122/372 (32%), Gaps = 75/372 (20%)
Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP- 668
P PS GP P P T S P LI + + GP A V A + P
Sbjct: 773 PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLI--QPRAPGPHAMPVAPGPALYPAPAYTPE 830
Query: 669 ------TKPLLSVNKSTSTPTSPGPRTHSTPSIPV--------------LTAGQSGLYSP 708
+ P V S P P PS P T + +P
Sbjct: 831 LGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAP 890
Query: 709 QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768
P+ + PA P +P P +P GAK +P Q H +S P
Sbjct: 891 IPSHTAPRPNPTPA-PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ----HHFSSGIPAG 945
Query: 769 QAAAAAGP---PLVAATPYSSYIPYNPQQ---------FPGQ-PAMMQPMAHYPSQPVFA 815
A GP P P ++ P PQQ FP Q P ++ P + YP P
Sbjct: 946 FPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPG 1005
Query: 816 PMLQSNPRMLTS-----GSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
+ Q P + T P S + P +PS P P PH A
Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSGALP-FPSPGPPQP-----------PHPPL---A 1050
Query: 871 HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 930
+ P P+T P G Q AAP ++ G Q+ P + PS PGP
Sbjct: 1051 YGPAPSTRPMGPQ-----AAPLTIR---------GPSSAGQSTPSPHLVPSPAPSPGPGP 1096
Query: 931 SAQSPQSSFPQP 942
P ++ P P
Sbjct: 1097 VPPRPPAAEPPP 1108
Score = 44.3 bits (103), Expect = 6e-04
Identities = 113/459 (24%), Positives = 150/459 (32%), Gaps = 118/459 (25%)
Query: 374 PGLSSLPPRGPHHLDNSSP--------------GPGSEARGINGGPSRMSPKAQRPLRGA 419
P SS P GPH+L P PG A + GP+ A P G
Sbjct: 775 PFPSSTGP-GPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGL 833
Query: 420 KTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE--PPIGSAVPTSSAS 477
SSP + V P VG PAP A P PP S + A
Sbjct: 834 VPRSSPQH------GVVSSPYVG----------VGPAPPVAGLPSAPPPQFSGPELAMAV 877
Query: 478 IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQ 537
P T++V S +P+ + P P + L K P Q
Sbjct: 878 RPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP--IPAQ 935
Query: 538 KRFQLE-----ELRKFGAQFKLQPSSSPENSLDPFPPR--ILKEEPKGKEKEVDGLLTSE 590
F + G Q + P P + P PP+ + + P + GLL
Sbjct: 936 HHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--- 992
Query: 591 PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPV 650
P SP P AP G G QPPPP +Q L G +D P
Sbjct: 993 PPQSPY--------------PYAPQPGVLG--QPPPPLHTQ-------LYPGPAQDPLPA 1029
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTST-PTSP--GPRTHSTPSIPVLTAGQSGLYS 707
P+ P P L+ + ST P P P T PS +AGQS
Sbjct: 1030 HSGALPF---PSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPS----SAGQS---- 1078
Query: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM 767
+P + P P + P G +PP+ PA+ PP
Sbjct: 1079 ---------------TPSPHLVPSPAPSPGP----------GPVPPR-----PPAAEPPP 1108
Query: 768 MQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQPAMMQP 804
AA L++++P S + Q P GQP ++QP
Sbjct: 1109 CLRRGAAAADLLSSSPESQ---HGGTQSPGGGQP-LLQP 1143
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 18/86 (20%)
Query: 26 RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQ 85
RPPGG P LPGP A PPG P A+ P P+ ++ + +P P PQ
Sbjct: 1508 RPPGGLESPVASLPGP----AEPPGLPPASLPESTPIPSS------SPPPLSSPLPEAPQ 1557
Query: 86 QHQERPGAAAIGSARGQSTGKGPPQS 111
+E P A S GPP S
Sbjct: 1558 PKEEPPVPEAPSS--------GPPSS 1575
Score = 38.1 bits (87), Expect = 0.046
Identities = 117/500 (23%), Positives = 163/500 (32%), Gaps = 91/500 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P +PK P R + P S+PP G PR P+
Sbjct: 718 PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAG----PR-------------LPD 760
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSIS-PASPKISLAPTDVKELSTKEPGRTLEPQEL 523
+GSA P P SS + PG +S P P PT + + + PG P
Sbjct: 761 TFLGSATPLHFPPSPFPSS-TGPGPHYLSGPLPPGTYSGPTQL--IQPRAPGPHAMP--- 814
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
PG L + + L P SSP++ + P G V
Sbjct: 815 -----VAPGP-------ALYPAPAYTPELGLVPRSSPQHGVVSSP-----YVGVGPAPPV 857
Query: 584 DGLLTSEP-------MGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC----PSQT 632
GL ++ P + V T +V + P + PPPPC P Q
Sbjct: 858 AGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917
Query: 633 GSPPVGLIKGEDKDEGPVAEQVKKSTLNP---NAKEFNP-----TKPLLSVNKSTSTPTS 684
P G + P+ Q S+ P A P +P S P
Sbjct: 918 LPTPYTYPAGAKQ---PIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ 974
Query: 685 PGPRTHSTPSIPVLTAGQS-GLYSPQY-ISYIPQ---IHMGPAVQAPQMYPYPVSNSVPG 739
P P H P L Q+ GL PQ Y PQ + P Q+YP P + +P
Sbjct: 975 PLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029
Query: 740 QQG--KYRGAKGSLPPQRSDQHQPA-SAPPMMQAAA---AAGPPLVAATPYSSYIPYNPQ 793
G + PP + PA S PM AA GP + S ++ +P
Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089
Query: 794 QFPG------QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP----QAIVSSSTPQYP 843
PG +P +P A +L S+P G+ Q ++ + +
Sbjct: 1090 PSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPT--KVD 1147
Query: 844 SAEQPTPQALYATVHQSYPH 863
+AE PQAL Y H
Sbjct: 1148 AAEGRRPQALRLIERDPYEH 1167
Score = 36.2 bits (82), Expect = 0.17
Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 28/132 (21%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGG-----LPGPLATSAAPPGPPAAASPC 58
P P P+ +QP P Q + P G P G P P + A P PP P
Sbjct: 919 PTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPL 978
Query: 59 LGPVAAAGSGLRRGAEGILAP--------------QPPPPQQHQERPGAA----AIGSAR 100
P A G+L P QPPPP Q PG A S
Sbjct: 979 QHPHLFPPQ-----APGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGA 1033
Query: 101 GQSTGKGPPQSP 112
GPPQ P
Sbjct: 1034 LPFPSPGPPQPP 1045
Score = 36.2 bits (82), Expect = 0.17
Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 19/121 (15%)
Query: 3 KPQPLQQPSQ------PQQPPPTQ-------QAVARRPPGGTSP-PNGGLPGPLATSAAP 48
+P P PSQ PQQP P Q QA PP SP P PG L P
Sbjct: 956 QPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP--QSPYPYAPQPGVLGQPPPP 1013
Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPP-PPQQHQERPGAAAIGSARGQSTGKG 107
P P+ A L + G PQPP PP + P +G T +G
Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFPSPG--PPQPPHPPLAYGPAPSTRPMGPQAAPLTIRG 1071
Query: 108 P 108
P
Sbjct: 1072 P 1072
Score = 35.8 bits (81), Expect = 0.23
Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 29/201 (14%)
Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
PL ++ GP + S G P S PP+ PH P P + G P +
Sbjct: 1013 PLHTQLYPGPAQDPLPAHS-GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI-- 1069
Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSA 470
+ P ++ SP PS S P P PPR P + EPP
Sbjct: 1070 --RGPSSAGQSTPSPHLVPSPAPSPGPGPV-----PPRPPAA-----------EPPPCLR 1111
Query: 471 VPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKV 530
++A + +S S G G+ SP + L PT V + P + R+ +
Sbjct: 1112 RGAAAADLLSSSPESQHG-GTQSPGGGQPLLQPTKVDAAEGRRP-------QALRLIERD 1163
Query: 531 PGLQNEQKRFQLEELRKFGAQ 551
P E+ R +EL F Q
Sbjct: 1164 PYEHPERLRQLQQELEAFRGQ 1184
Score = 32.3 bits (72), Expect = 2.5
Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 10/94 (10%)
Query: 4 PQPLQQPSQPQQPPPTQ-QAVARRPPG---------GTSPPNGGLPGPLATSAAPPGPPA 53
P P P QP PP A + RP G G S P P + P P
Sbjct: 1035 PFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGP 1094
Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQH 87
P P A LRRGA P QH
Sbjct: 1095 GPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH 1128
Score = 32.0 bits (71), Expect = 3.3
Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 21/148 (14%)
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAP--APISASCPEPPIGSAVPTSSASI 478
T++ S RP G P G PP P ++ P PI +S P PP+ S +P +
Sbjct: 1501 TIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSP-PPLSSPLPEAPQ-- 1557
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538
P + AP+ S+ E +L P+ + + + G Q K
Sbjct: 1558 --------------PKEEPPVPEAPSSGPPSSSLELLASLTPEAFS-LDSSLRGKQRMSK 1602
Query: 539 RFQLEELRKFGAQFKLQPSSSPENSLDP 566
L+ G + +PS P + LDP
Sbjct: 1603 HNFLQAHNGQGLR-ATRPSDDPLSLLDP 1629
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 25/110 (22%)
Query: 927 PPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
PPG +SP +S P PA + LP T I ++ PP +P P
Sbjct: 1509 PPG-GLESPVASLPGPAEPPGLPPASLPES-------------TPIPSSSPPPLSSPLP- 1553
Query: 987 QVMLLHPPQSHGGPPQGAVPQSGVPA-----LSASTPSPYPYIGHPQGEQ 1031
PQ PP P SG P+ L++ TP + +G+Q
Sbjct: 1554 -----EAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQ 1598
Score = 31.2 bits (69), Expect = 5.6
Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%)
Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLL-TSEPMGSPVSSKTESVSDKEDKPPLAPSGGT 618
P +S+ ++ P G E V L +EP G P +S ES PP S
Sbjct: 1494 PISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLP 1553
Query: 619 EGP---EQPPPPCPSQTGSPPVGL 639
E P E+PP P +G P L
Sbjct: 1554 EAPQPKEEPPVPEAPSSGPPSSSL 1577
Score = 30.8 bits (68), Expect = 7.3
Identities = 30/111 (27%), Positives = 36/111 (32%), Gaps = 5/111 (4%)
Query: 7 LQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAG 66
+Q P P A PP PP LP P A P A + A
Sbjct: 887 IQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGF 946
Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR-----GQSTGKGPPQSP 112
R G + PQP P Q +P + Q+ G PPQSP
Sbjct: 947 PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSP 997
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 70.9 bits (172), Expect = 6e-12
Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
P +A GP+ +PK P + S+ P S T+ P P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
+PK AP P P A T+ P T+ + +P +PK APT
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 312
Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
+ KEP T P+E K P ++ + A K P++ E +
Sbjct: 313 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365
Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
P KE KE EP +P ++K+ + KE AP+ P P P
Sbjct: 366 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 418
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
P+ T P K+ P + T P +P + K + +TP P
Sbjct: 419 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
P T + P+ P +P+ ++ P PA P+ ++ + P +
Sbjct: 475 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 521
Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
P + +PA P +AAA P A T P P+ +PA
Sbjct: 522 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 566
Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
P P+ P AP P T P+ + ++T P + ++P P T
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 625
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
+ P +P P TTP G+ P + + AP+ + A + AP G P
Sbjct: 626 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684
Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
T T P+ P P+ +P+ P
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAP 710
Score = 67.8 bits (164), Expect = 5e-11
Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%)
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S
Sbjct: 191 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 240
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
P T PA APT KE +TKEP T P+E A K P
Sbjct: 241 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 287
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
S+P +P P K P KE EP +P
Sbjct: 288 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 327
Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
+ K + + KE P P++P P P + + P K+ P +
Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387
Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
T +A + + +TP P P T P+ T + +P+
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 443
Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
P PA P+ P P + P A + P + + P + A
Sbjct: 444 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
P A T P P++ P +PA P A P+ P AP P T
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
+ P P PT T+ + P + + P TT +
Sbjct: 562 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
AP+ + G AP P T GT P+ P+ +P+ P+ A
Sbjct: 616 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
+ P T+ +T T P P P P
Sbjct: 673 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
++ +P + T S+P+ PS T+ P P + P +PK AP P
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
P A T+ P T P +P +PK L PT ++L +T E P
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 511
Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
+ELA + P ++ +++P +P P P K
Sbjct: 512 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 560
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
E KE + P G+ ++ E KP T E C
Sbjct: 561 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
+ P G K+ P A K T KE PT P K + T+ GP
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 676
Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
T +T P T + P PA P+ P P + P
Sbjct: 677 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 716
Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
PP S+ P + P + + P ++A P + +P++ PG P P A
Sbjct: 717 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 772
Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
P A L++ P T+ +++T + ++ T Q T
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832
Query: 859 QSYPHHATQLHAHQPQPATTPT 880
+ P T L P T T
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTT 854
Score = 61.2 bits (147), Expect = 5e-09
Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P+ P P P + P +P + P +P+ + P PA
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
P + P+P + P PT++ S P T+ P +P +PK
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 417
Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
+PT KE + KEP T P++ A K P ++ + K
Sbjct: 418 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476
Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
++P+ + P ++ P+ E T E + + + +E P
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536
Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
+ P++P P P + P E P A K T KE PT P
Sbjct: 537 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592
Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
K + T+ P T +T P P G A P+ P P
Sbjct: 593 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 633
Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
+ P KG+ P + +PA P A P +T P
Sbjct: 634 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
P++ P +PA P P+ P P S T+ P I S STP+
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
+ +PTP+AL + + A +P+ TT + P++ AAP
Sbjct: 747 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804
Query: 895 QHQA 898
+ A
Sbjct: 805 KETA 808
Score = 45.1 bits (105), Expect = 4e-04
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P+ +PK P A T + P+ TS P P + P +PK AP P
Sbjct: 655 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
P TS S P T+ S ++P++S PT E S KEPG P
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 768
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
A K + + +LR ++PE + P++ KE EK
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 815
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
+ +T+ +++ S + ++ P LAP T PE+
Sbjct: 816 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
P T S K P ++ K+ P + + T P + K+T TP
Sbjct: 870 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919
Query: 683 --TSPGPRTHSTPSI 695
TS P + T I
Sbjct: 920 KMTSTMPELNPTSRI 934
Score = 42.7 bits (99), Expect = 0.002
Identities = 110/529 (20%), Positives = 158/529 (29%), Gaps = 54/529 (10%)
Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
S P S S +T +KE + T + + + K KD
Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
P ++ + K T P A E P L+ K TPT+P +TP P T +S +P
Sbjct: 189 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 244
Query: 709 QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755
+ + P PA P+ P P + P P
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Query: 756 SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815
+ +PA P A P TP + P + P +P P +P A
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 357
Query: 816 PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871
P P T +P P PT T + P T A
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 416
Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928
+P P TT + + AP+ + A P +P A T T P+ P
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 472
Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV 988
P+ +P+ + P P T A A P AP P+
Sbjct: 473 EPAPTTPKETAP-----------TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521
Query: 989 MLLHPPQSHG-GPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP----GQAPGFPGGAD 1043
P+ P+ A P + P A T P P+ P AP P G
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNT--PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 1044 DRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDP 1092
L + ++ P+S +CD AP A + P
Sbjct: 580 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 70.9 bits (172), Expect = 6e-12
Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
P +A GP+ +PK P + S+ P S T+ P P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
+PK AP P P A T+ P T+ + +P +PK APT
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 353
Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
+ KEP T P+E K P ++ + A K P++ E +
Sbjct: 354 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406
Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
P KE KE EP +P ++K+ + KE AP+ P P P
Sbjct: 407 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 459
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
P+ T P K+ P + T P +P + K + +TP P
Sbjct: 460 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
P T + P+ P +P+ ++ P PA P+ ++ + P +
Sbjct: 516 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 562
Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
P + +PA P +AAA P A T P P+ +PA
Sbjct: 563 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 607
Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
P P+ P AP P T P+ + ++T P + ++P P T
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 666
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
+ P +P P TTP G+ P + + AP+ + A + AP G P
Sbjct: 667 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725
Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
T T P+ P P+ +P+ P
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAP 751
Score = 67.8 bits (164), Expect = 5e-11
Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%)
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S
Sbjct: 232 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 281
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
P T PA APT KE +TKEP T P+E A K P
Sbjct: 282 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 328
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
S+P +P P K P KE EP +P
Sbjct: 329 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 368
Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
+ K + + KE P P++P P P + + P K+ P +
Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428
Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
T +A + + +TP P P T P+ T + +P+
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 484
Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
P PA P+ P P + P A + P + + P + A
Sbjct: 485 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
P A T P P++ P +PA P A P+ P AP P T
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
+ P P PT T+ + P + + P TT +
Sbjct: 603 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
AP+ + G AP P T GT P+ P+ +P+ P+ A
Sbjct: 657 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
+ P T+ +T T P P P P
Sbjct: 714 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
++ +P + T S+P+ PS T+ P P + P +PK AP P
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
P A T+ P T P +P +PK L PT ++L +T E P
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 552
Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
+ELA + P ++ +++P +P P P K
Sbjct: 553 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 601
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
E KE + P G+ ++ E KP T E C
Sbjct: 602 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
+ P G K+ P A K T KE PT P K + T+ GP
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 717
Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
T +T P T + P PA P+ P P + P
Sbjct: 718 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 757
Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
PP S+ P + P + + P ++A P + +P++ PG P P A
Sbjct: 758 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 813
Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
P A L++ P T+ +++T + ++ T Q T
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873
Query: 859 QSYPHHATQLHAHQPQPATTPT 880
+ P T L P T T
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTT 895
Score = 61.2 bits (147), Expect = 5e-09
Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P+ P P P + P +P + P +P+ + P PA
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
P + P+P + P PT++ S P T+ P +P +PK
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 458
Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
+PT KE + KEP T P++ A K P ++ + K
Sbjct: 459 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517
Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
++P+ + P ++ P+ E T E + + + +E P
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577
Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
+ P++P P P + P E P A K T KE PT P
Sbjct: 578 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633
Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
K + T+ P T +T P P G A P+ P P
Sbjct: 634 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 674
Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
+ P KG+ P + +PA P A P +T P
Sbjct: 675 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727
Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
P++ P +PA P P+ P P S T+ P I S STP+
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
+ +PTP+AL + + A +P+ TT + P++ AAP
Sbjct: 788 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845
Query: 895 QHQA 898
+ A
Sbjct: 846 KETA 849
Score = 45.1 bits (105), Expect = 4e-04
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P+ +PK P A T + P+ TS P P + P +PK AP P
Sbjct: 696 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
P TS S P T+ S ++P++S PT E S KEPG P
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 809
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
A K + + +LR ++PE + P++ KE EK
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 856
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
+ +T+ +++ S + ++ P LAP T PE+
Sbjct: 857 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
P T S K P ++ K+ P + + T P + K+T TP
Sbjct: 911 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960
Query: 683 --TSPGPRTHSTPSI 695
TS P + T I
Sbjct: 961 KMTSTMPELNPTSRI 975
Score = 42.7 bits (99), Expect = 0.002
Identities = 110/529 (20%), Positives = 158/529 (29%), Gaps = 54/529 (10%)
Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
S P S S +T +KE + T + + + K KD
Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
P ++ + K T P A E P L+ K TPT+P +TP P T +S +P
Sbjct: 230 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 285
Query: 709 QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755
+ + P PA P+ P P + P P
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Query: 756 SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815
+ +PA P A P TP + P + P +P P +P A
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 398
Query: 816 PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871
P P T +P P PT T + P T A
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 457
Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928
+P P TT + + AP+ + A P +P A T T P+ P
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 513
Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV 988
P+ +P+ + P P T A A P AP P+
Sbjct: 514 EPAPTTPKETAP-----------TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562
Query: 989 MLLHPPQSHG-GPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP----GQAPGFPGGAD 1043
P+ P+ A P + P A T P P+ P AP P G
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNT--PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 1044 DRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDP 1092
L + ++ P+S +CD AP A + P
Sbjct: 621 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,721,630
Number of Sequences: 37866
Number of extensions: 4674755
Number of successful extensions: 52513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 365
Number of HSP's successfully gapped in prelim test: 2396
Number of HSP's that attempted gapping in prelim test: 23160
Number of HSP's gapped (non-prelim): 22184
length of query: 1097
length of database: 18,247,518
effective HSP length: 113
effective length of query: 984
effective length of database: 13,968,660
effective search space: 13745161440
effective search space used: 13745161440
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.