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Search of human proteins with 25952108
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 998 0.0
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 513 e-145
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 431 e-120
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 401 e-112
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 398 e-111
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 345 4e-95
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens] 328 7e-90
gi|20070166 potassium voltage-gated channel, subfamily F, member... 296 4e-80
gi|27436996 potassium voltage-gated channel, subfamily G, member... 281 7e-76
gi|27436988 potassium voltage-gated channel, subfamily G, member... 281 1e-75
gi|27436993 potassium voltage-gated channel, subfamily G, member... 259 3e-69
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 257 2e-68
gi|19071574 potassium voltage-gated channel, subfamily G, member... 256 3e-68
gi|21217561 Shaw-related voltage-gated potassium channel protein... 246 4e-65
gi|21217563 Shaw-related voltage-gated potassium channel protein... 246 4e-65
gi|24497458 Shaw-related voltage-gated potassium channel protein... 246 4e-65
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 245 6e-65
gi|163792201 Shaw-related voltage-gated potassium channel protei... 245 6e-65
gi|88758576 Shaw-related voltage-gated potassium channel protein... 241 8e-64
gi|24497462 Shaw-related voltage-gated potassium channel protein... 241 8e-64
gi|24497464 Shaw-related voltage-gated potassium channel protein... 241 8e-64
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 239 5e-63
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 236 3e-62
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 236 5e-62
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 236 5e-62
gi|24497460 Shaw-related voltage-gated potassium channel protein... 233 4e-61
gi|88758565 potassium voltage-gated channel, shaker-related subf... 231 1e-60
gi|119395748 potassium voltage-gated channel subfamily A member ... 230 2e-60
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 228 7e-60
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 227 2e-59
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 998 bits (2580), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDY 60
MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDY
Sbjct: 1 MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDY 60
Query: 61 SVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNR 120
SVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNR
Sbjct: 61 SVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNR 120
Query: 121 YQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAY 180
YQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAY
Sbjct: 121 YQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAY 180
Query: 181 CLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVR 240
CLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVR
Sbjct: 181 CLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVR 240
Query: 241 LAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRI 300
LAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRI
Sbjct: 241 LAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRI 300
Query: 301 LKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPIC 360
LKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPIC
Sbjct: 301 LKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPIC 360
Query: 361 WWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDID 420
WWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDID
Sbjct: 361 WWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDID 420
Query: 421 VDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDIC 480
VDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDIC
Sbjct: 421 VDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDIC 480
Query: 481 NTTSLENCTAK 491
NTTSLENCTAK
Sbjct: 481 NTTSLENCTAK 491
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 513 bits (1320), Expect = e-145
Identities = 252/445 (56%), Positives = 325/445 (73%), Gaps = 4/445 (0%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
+ +NVGGFK+ + TLLRFP TRLG+LL CHS EAILELCDDY +E+YFDRNP LF
Sbjct: 19 IRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELF 78
Query: 77 RYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQK 136
YVL+FY+TGKLHVM ELCVFSF QEIEYWGINE FIDSCCS Y RK E ++ WD++
Sbjct: 79 PYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQ 138
Query: 137 SHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVL 196
S ST SSF+E F + KFD G R+++W+ ++NP Y + +++ +I S+ VV+
Sbjct: 139 SDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVM 198
Query: 197 ASIVAMCVHSMSEFQNEDGE---VDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKN 253
SI+ MC++S+ +FQ D + +DP E VE IAWFT EL R A AP KF+KN
Sbjct: 199 GSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKN 258
Query: 254 PLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSL 313
LN+ID +SI+PFY TL V+ E + + N+G+V Q+LRLMRIFRILKLARHS GLRSL
Sbjct: 259 ALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSL 318
Query: 314 GATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGY 373
GATL++SY EVGLLLL+LSVGISIFSV+ Y++EK+++ L +IP CWWWAT+SMTTVGY
Sbjct: 319 GATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEEN-EGLATIPACWWWATVSMTTVGY 377
Query: 374 GDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCH 433
GD P T AGKL AS CI+ GILVV LPIT+IFNKFS +Y++QK ++ S D +
Sbjct: 378 GDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMK 437
Query: 434 ELPYFNIRDIYAQRMHTFITSLSSV 458
E+P N+RD YA ++ + + SL+++
Sbjct: 438 EVPSVNLRDYYAHKVKSLMASLTNM 462
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 431 bits (1107), Expect = e-120
Identities = 217/427 (50%), Positives = 295/427 (69%), Gaps = 20/427 (4%)
Query: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDR 71
+ +E + +NVGG ++ + L RFP TRLG+L SEE LCDDY A +E+YFDR
Sbjct: 47 RSDEALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDR 106
Query: 72 NPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEK 131
+P F +L+FY TG LHV++ELCVF+F QE +YWG+ E + +CC RY ER+
Sbjct: 107 HPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERR-LTQPH 165
Query: 132 DWDQKSHDVST-DSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAIS 190
WD+ S S+ D +E S ++EL ++ R G+LR+++W+ MENP Y L +KL +
Sbjct: 166 AWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCV 225
Query: 191 SLSVVLASIVAMCVHSMSEFQ---------------NEDGEVDDPVLEGVEIACIAWFTG 235
S+SVVLASI AMC+HS+ E+Q + +G DDPVL +E CIAWF+
Sbjct: 226 SISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSF 285
Query: 236 ELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATL--AVDTKEEESEDIENMGKVVQILR 293
E++ RL AP + F+ +PLN+ID VS++PFY TL V ++ ++ ++GKVVQ+ R
Sbjct: 286 EVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFGHLGKVVQVFR 345
Query: 294 LMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSS 353
LMRIFR+LKLARHS GLRSLGATL+HSY EVG+LLL+L+VG+S+FS + Y+ EK++
Sbjct: 346 LMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDV-G 404
Query: 354 LTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYY 413
+IP CWWW T+SMTTVGYGD PVT+AGKL AS CI+ GILVVALPITIIFNKFS +Y
Sbjct: 405 FNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFY 464
Query: 414 QKQKDID 420
++QK ++
Sbjct: 465 RRQKALE 471
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 401 bits (1030), Expect = e-112
Identities = 202/459 (44%), Positives = 299/459 (65%), Gaps = 18/459 (3%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
V +NVGG V TL R P TRLGKL C++ E++LE+CDDY++ + EY+FDR+P F
Sbjct: 37 VKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAF 96
Query: 77 RYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQK 136
+LNFY TGKLH+MEE+C SF QE++YWGI+E++++SCC RY ++KE+ +E
Sbjct: 97 TSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNE------ 150
Query: 137 SHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVL 196
+ E ++ E+E E+FD RKK+W +E P ++AK++AI S+ ++
Sbjct: 151 ------ELRREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSILFIV 204
Query: 197 ASIVAMCVHSMSEFQNED--GEVDDP-VLEGVEIACIAWFTGELAVRLAAAPCQKKFWKN 253
S +A+ ++++ E Q D G+++D L VE CIAWFT E +R ++P + KF+K
Sbjct: 205 LSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKG 264
Query: 254 PLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSL 313
PLN+ID ++I+P+Y T+ + + +N+ +VVQI R+MRI RILKLARHS GL+SL
Sbjct: 265 PLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSL 324
Query: 314 GATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGY 373
G TLR SY+E+GLL+LFL++GI IFS L++ EKD+ + TSIP +WWATI+MTTVGY
Sbjct: 325 GFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGY 384
Query: 374 GDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCH 433
GD +P TL GK++ C I G+LV+ALPI II N FS++Y++QK + +A E+
Sbjct: 385 GDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAK 444
Query: 434 ---ELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTD 469
+ N++D +A+ M ++ G + DS D
Sbjct: 445 RNGSIVSMNLKDAFARSMELIDVAVEKAGESANTKDSAD 483
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 398 bits (1022), Expect = e-111
Identities = 201/467 (43%), Positives = 298/467 (63%), Gaps = 18/467 (3%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
V LNVGG V TL R P TRLGKL C++ +++LE+CDDYS+ D EY+FDR+P F
Sbjct: 33 VRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAF 92
Query: 77 RYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQK 136
+LNFY TG+LH+MEE+C SF QE++YWGI+E++++SCC RY ++KE+ +E
Sbjct: 93 TSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNE------ 146
Query: 137 SHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVL 196
+ E +L E+E E+FD + RKK+W +E P ++AK++AI S+ ++
Sbjct: 147 ------ELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIV 200
Query: 197 ASIVAMCVHSMSEFQNEDG---EVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKN 253
S +A+ ++++ E Q+ D D+P L VE CIAWFT E +R ++P + KF+K
Sbjct: 201 LSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKG 260
Query: 254 PLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSL 313
PLN ID ++I+P+Y T+ + + +N+ +VVQI R+MRI RILKLARHS GL+SL
Sbjct: 261 PLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSL 320
Query: 314 GATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGY 373
G TLR SY+E+GLL+LFL++GI IFS L++ EKD+ + SIP +WWATI+MTTVGY
Sbjct: 321 GFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGY 380
Query: 374 GDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCH 433
GD +P TL GK++ C I G+LV+ALPI II N FS++Y++QK + +A E+
Sbjct: 381 GDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAK 440
Query: 434 ---ELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNE 477
+ N++D +A+ + + G + D + + N+
Sbjct: 441 RNGSIVSMNMKDAFARSIEMMDIVVEKNGENMGKKDKVQDNHLSPNK 487
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 345 bits (886), Expect = 4e-95
Identities = 192/446 (43%), Positives = 267/446 (59%), Gaps = 32/446 (7%)
Query: 19 LNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSE----------EAILELCDDYSVADKEYY 68
+NVGG + + Q L FPHTRLGKL + + LELCDD + D EY+
Sbjct: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
Query: 69 FDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEEN 128
FDR+ FRYVL++Y TG+LHVME+LC SF QEI+YWGI+EL IDSCC +RY RKE +
Sbjct: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
Query: 129 HEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIA 188
D+ + + D + E+ F +R+K+W +E P +A++
Sbjct: 163 ETLDFKKDTEDQESQHESEQD---------FSQGPCPTVRQKLWNILEKPGSSTAARIFG 213
Query: 189 ISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQK 248
+ S+ V+ SI+ M + S E +D +LE +E CI+WFTGE +R +
Sbjct: 214 VISIIFVVVSIINMALMSA-----ELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRC 268
Query: 249 KFWKNPLNIIDFVSIIPFYATLAVDTKE--EESEDIENMGKVVQILRLMRIFRILKLARH 306
+F + NIID ++I+PFY TL V++ + ++++EN+G++VQ+LRL+R R+LKL RH
Sbjct: 269 RFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRH 328
Query: 307 SVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATI 366
S GLRSLG T+ Y EVGLLLLFLSVGISIFS + Y E+ ++ TS+P WWWAT
Sbjct: 329 STGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATT 388
Query: 367 SMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSE 426
SMTTVGYGD P T GK++A CI+ GILV+ALPI II ++FS Y K +
Sbjct: 389 SMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQR 448
Query: 427 DAPEK------CHELPYFNIRDIYAQ 446
+A +K N+RD+YA+
Sbjct: 449 EALKKLTKNIATDSYISVNLRDVYAR 474
>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
Length = 545
Score = 328 bits (841), Expect = 7e-90
Identities = 171/414 (41%), Positives = 257/414 (62%), Gaps = 21/414 (5%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
+N+NVGG +D L FP TRLG+L T S L LCDDY EY+FDR+P++F
Sbjct: 99 LNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVF 158
Query: 77 RYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQK 136
+ V NFY +G L V++ LC F +E+ YWG+ + CC ++ER++E E+ Q
Sbjct: 159 QLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQ- 217
Query: 137 SHDVSTDSSFEESSLFEKELEKFDTLRF-GQLRKKIWIRMENPAYCLSAKLIAISSLSVV 195
H++ + EE+ E F +RF G R+++W ME P ++AK I ++S + V
Sbjct: 218 -HELRAQAQVEEAE------ELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFV 270
Query: 196 LASIVAMCVHSMSEFQNEDGEVDD-----PVLEGVEIACIAWFTGELAVRLAAAPCQKKF 250
L S+VA+ ++++ E Q G+ + P+LE VE+ C+ +FT E +RLA+ P ++F
Sbjct: 271 LVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRF 330
Query: 251 WKNPLNIIDFVSIIPFYATLAVDTKEEESED-------IENMGKVVQILRLMRIFRILKL 303
++ LN++D V+I+P Y L ++ E + +G+V++++RLMRIFRILKL
Sbjct: 331 ARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKL 390
Query: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWW 363
ARHS GLR+ G TLR Y +VG LLLF+++GI FS +YSVE D +++ T+IP WWW
Sbjct: 391 ARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPSTNFTTIPHSWWW 450
Query: 364 ATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQK 417
A +S++TVGYGD +P T G+ A CI GI++ +PI+I++NKFS YY K K
Sbjct: 451 AAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLK 504
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 296 bits (757), Expect = 4e-80
Identities = 158/415 (38%), Positives = 247/415 (59%), Gaps = 23/415 (5%)
Query: 13 DEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTC--HSEEAILELCDDYSVADKEYYFD 70
D E+V +NVGG +Q + L ++P TRL +L+ C + I LCDDY +E+YFD
Sbjct: 22 DIEIV-VNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFD 80
Query: 71 RNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHE 130
R+P F+ V+ YY G++H+ + +C F E+++W ++ F+D CC + E++EE E
Sbjct: 81 RDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEE 140
Query: 131 --KDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIA 188
+ D+ D++ R+ + +K +W +E P A+++A
Sbjct: 141 IARRVQLILDDLGVDAA---------------EGRWRRCQKCVWKFLEKPESSCPARVVA 185
Query: 189 ISSLSVVLASIVAMCVHSMSEFQNEDGE---VDDPVLEGVEIACIAWFTGELAVRLAAAP 245
+ S ++L S V MC+ ++ E Q D E V+ P LE VE ACI WFT E +RL ++P
Sbjct: 186 VLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSP 245
Query: 246 CQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLAR 305
+ F + +NI+D ++I+PFY +L + ++ N+ + VQ LR+MRI RI KLAR
Sbjct: 246 NKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLAR 305
Query: 306 HSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWAT 365
HS GL++L L+ S+ E+GLLL++L+VGI +FS L Y++E+ + SIP +WWA
Sbjct: 306 HSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAI 365
Query: 366 ISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDID 420
I+MTTVGYGD +P T GKL A+ +CG++ +ALPI I N F +YY KQ+ ++
Sbjct: 366 ITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLE 420
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 281 bits (720), Expect = 7e-76
Identities = 157/417 (37%), Positives = 243/417 (58%), Gaps = 32/417 (7%)
Query: 19 LNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRY 78
+NVGG + + STL RFP +RL KL C S E I++LCDDY +E++FDR+PS F
Sbjct: 63 INVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGV 122
Query: 79 VLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEE------NHEKD 132
+++F GKL +++E+C SF +E+ YWGI E ++ CC + + EE H +D
Sbjct: 123 IVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHRED 182
Query: 133 WDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSL 192
++ + +S R+G ++ +ENP L K+ A S+
Sbjct: 183 VLRQQRETRRPASHSS--------------RWGLCMNRLREMVENPQSGLPGKVFACLSI 228
Query: 193 SVVLASIVAMCVHSMSEFQNEDGEVDDP----VLEGVEIACIAWFTGELAVRLAAAPCQK 248
V + V++CV +M + + E+ + + + VE C+AWF+ E +R A +
Sbjct: 229 LFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKC 288
Query: 249 KFWKNPLNIIDFVSIIPFYATLAVDTKEEE-------SEDIENMGKVVQILRLMRIFRIL 301
+F++ PLNIID ++I P+Y +LAV + E S +E +G V+++LR +RI ++
Sbjct: 289 QFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVM 348
Query: 302 KLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDD-HTSSLTSIPIC 360
+LARHS+GL++LG T+R E GLLLLFL+V I++FS L+Y EK+ TSIP
Sbjct: 349 RLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPAS 408
Query: 361 WWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQK 417
+WWA ISMTTVGYGD P ++ G+++A + I+ GIL++A P T IF+ FS Y + K
Sbjct: 409 YWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELK 465
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 281 bits (718), Expect = 1e-75
Identities = 159/421 (37%), Positives = 243/421 (57%), Gaps = 18/421 (4%)
Query: 9 RPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYY 68
+P + +NVGG K S+ +TL FP TRLG+L C + + IL +CDDY V E++
Sbjct: 57 QPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFF 116
Query: 69 FDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEEN 128
FDRNP F +L F GKL ++ E+C SF +E+ YWGI E +D CC RY ++ EE
Sbjct: 117 FDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEF 176
Query: 129 HEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIA 188
E +++ D + DS +S E R G+ +++ +E P L K+ A
Sbjct: 177 AEM-VEREEEDDALDSEGRDS-----EGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFA 230
Query: 189 ISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEG----VEIACIAWFTGELAVRLAAA 244
S+ V + V + V ++ + E+ + + VE C+ WF+ E +RL A
Sbjct: 231 CLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQA 290
Query: 245 PCQKKFWKNPLNIIDFVSIIPFYATLAVD-------TKEEESEDIENMGKVVQILRLMRI 297
P + F ++PL +ID V+I+P+Y TL VD + ++ +G V+++LR +RI
Sbjct: 291 PSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRI 350
Query: 298 FRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTS-SLTS 356
+++LARHS+GL++LG T R E GLLLLFL V I++F+ L+Y +E + S TS
Sbjct: 351 LYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTS 410
Query: 357 IPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQ 416
IP C+WWA I+MTTVGYGD P + G+++A + I+ GIL++A P+T IF+ FS+ Y +
Sbjct: 411 IPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLEL 470
Query: 417 K 417
K
Sbjct: 471 K 471
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 259 bits (663), Expect = 3e-69
Identities = 140/413 (33%), Positives = 229/413 (55%), Gaps = 26/413 (6%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
V LNVGG + S+ + L FP R+ +L C SE +LE+CDDY EY+FDR+ F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 77 RYVLNFYYT-GKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQ 135
++L + GKL +C SF E+ YWG+ ++ CC R +R + +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTY------ 124
Query: 136 KSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIR-----MENPAYCLSAKLIAIS 190
T S +E + ++ + R+ W+ E P L+A+++A
Sbjct: 125 ------TFYSADEPGVLGRDEARPGGAEAAPSRR--WLERMRRTFEEPTSSLAAQILASV 176
Query: 191 SLSVVLASIVAMCVHSMSEFQNE--DGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQK 248
S+ V+ S+V +C ++ +++N D D +E CI WFT E VR + +
Sbjct: 177 SVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKC 236
Query: 249 KFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSV 308
+F K PLNIID ++I P+Y ++ + E+ ++ G +++LR+MRIF ++KLARH +
Sbjct: 237 EFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFI 296
Query: 309 GLRSLGATLRHSYHEVGLLLLFLSVGISIFS----VLIYSVEKDDHTSSLTSIPICWWWA 364
GL++LG TL+ Y E+ +LL+F+ V ++IFS +L + ++ + TSIP WW
Sbjct: 297 GLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWV 356
Query: 365 TISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQK 417
ISMTTVGYGD +P+T+ G+++ C++ GI+++ALPIT I++ F + Y + K
Sbjct: 357 IISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 257 bits (656), Expect = 2e-68
Identities = 147/409 (35%), Positives = 238/409 (58%), Gaps = 17/409 (4%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
V +NVGG + + + L R P RL +L C + +L +CDDY V+ E++FDR+P F
Sbjct: 19 VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAF 78
Query: 77 RYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQK 136
R ++ GKL ++ C +F E+ YWGI+E ++ CC R + R+EE E
Sbjct: 79 RAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE------ 132
Query: 137 SHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVL 196
+ T+ + S + L L+ G R+++ ++NP L+ KL A S+S V
Sbjct: 133 ARAGPTERGAQGSP--ARALGPRGRLQRG--RRRLRDVVDNPHSGLAGKLFACVSVSFVA 188
Query: 197 ASIVAMCVHSMSEFQNED--GEVDDPV--LEGVEIACIAWFTGELAVRLAAAPCQKKFWK 252
+ V +C+ +M + + E+ GE L +E C+AWF+ E +R A + F +
Sbjct: 189 VTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLR 248
Query: 253 NPLNIIDFVSIIPFYATLAVDTKEEE--SEDIENMGKVVQILRLMRIFRILKLARHSVGL 310
PLNIID ++++PFY +L + ++ +E G V+++LR +R+ +++LARHS+GL
Sbjct: 249 APLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGL 308
Query: 311 RSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKD-DHTSSLTSIPICWWWATISMT 369
RSLG T+R E GLLLLFL V +++F+ L++ E++ +S+P +WWA ISMT
Sbjct: 309 RSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMT 368
Query: 370 TVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKD 418
TVGYGD P +L G+++A + I+ GIL++A P+T IF+ FS+ Y + K+
Sbjct: 369 TVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKE 417
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 256 bits (654), Expect = 3e-68
Identities = 142/424 (33%), Positives = 234/424 (55%), Gaps = 37/424 (8%)
Query: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
V LNVGG + S+ + L FP R+ +L C SE +LE+CDDY EY+FDR+ F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 77 RYVLNFYYT-GKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQ 135
++L + GKL +C SF E+ YWG+ ++ CC R +R + +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTY------ 124
Query: 136 KSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIR-----MENPAYCLSAKLIAIS 190
T S +E + ++ + R+ W+ E P L+A+++A
Sbjct: 125 ------TFYSADEPGVLGRDEARPGGAEAAPSRR--WLERMRRTFEEPTSSLAAQILASV 176
Query: 191 SLSVVLASIVAMCVHSMSEFQN---EDGEVDD-------PVLEG---VEIACIAWFTGEL 237
S+ V+ S+V +C ++ +++N ++ +DD P E +E CI WFT E
Sbjct: 177 SVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAEC 236
Query: 238 AVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRI 297
VR + + +F K PLNIID ++I P+Y ++ + E+ ++ G +++LR+MRI
Sbjct: 237 IVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRI 296
Query: 298 FRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFS----VLIYSVEKDDHTSS 353
F ++KLARH +GL++LG TL+ Y E+ +LL+F+ V ++IFS +L + ++ +
Sbjct: 297 FWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKD 356
Query: 354 LTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYY 413
TSIP WW ISMTTVGYGD +P+T+ G+++ C++ GI+++ALPIT I++ F + Y
Sbjct: 357 FTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 416
Query: 414 QKQK 417
+ K
Sbjct: 417 HELK 420
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 246 bits (627), Expect = 4e-65
Identities = 154/480 (32%), Positives = 235/480 (48%), Gaps = 82/480 (17%)
Query: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELC-------------- 57
++ E V LNVGG + +STL P TRL L + L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPP 64
Query: 58 ----------------------------DDYSVADKEYYFDRNPSLFRYVLNFYYTGKLH 89
D+ +E++FDR+P +F YVLN+Y TGKLH
Sbjct: 65 PRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLH 124
Query: 90 VMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEES 149
++C F +E+ +WGI+E ++ CC Y++ ++ D + + D +E
Sbjct: 125 CPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDED 184
Query: 150 SLFEKELEKFDTLRFG----------QLRKKIWIRMENPAYCLSAKLIAISSLSVVLASI 199
L K L D G +L+ ++W E+P +A+ IA +SL +L SI
Sbjct: 185 -LAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSI 243
Query: 200 VAMCVHSMSEFQNEDGEVD----------------DPVLEGVEIACIAWFTGELAVRLAA 243
C+ + F + + DP L VE C+ WFT E VR+
Sbjct: 244 TTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVF 303
Query: 244 APCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKL 303
+P + +F KN LNIIDFV+I+PFY L V S+ +++ ++++R +RI RI KL
Sbjct: 304 SPNKLEFIKNLLNIIDFVAILPFY--LEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKL 361
Query: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK----------DDHTSS 353
RH VGLR LG TLR S +E LL++FL++G+ IF+ +IY E+ +HT
Sbjct: 362 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQ- 420
Query: 354 LTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYY 413
+IPI +WWA ++MTT+GYGD +P T +G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 421 FKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 246 bits (627), Expect = 4e-65
Identities = 154/480 (32%), Positives = 235/480 (48%), Gaps = 82/480 (17%)
Query: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELC-------------- 57
++ E V LNVGG + +STL P TRL L + L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPP 64
Query: 58 ----------------------------DDYSVADKEYYFDRNPSLFRYVLNFYYTGKLH 89
D+ +E++FDR+P +F YVLN+Y TGKLH
Sbjct: 65 PRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLH 124
Query: 90 VMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEES 149
++C F +E+ +WGI+E ++ CC Y++ ++ D + + D +E
Sbjct: 125 CPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDED 184
Query: 150 SLFEKELEKFDTLRFG----------QLRKKIWIRMENPAYCLSAKLIAISSLSVVLASI 199
L K L D G +L+ ++W E+P +A+ IA +SL +L SI
Sbjct: 185 -LAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSI 243
Query: 200 VAMCVHSMSEFQNEDGEVD----------------DPVLEGVEIACIAWFTGELAVRLAA 243
C+ + F + + DP L VE C+ WFT E VR+
Sbjct: 244 TTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVF 303
Query: 244 APCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKL 303
+P + +F KN LNIIDFV+I+PFY L V S+ +++ ++++R +RI RI KL
Sbjct: 304 SPNKLEFIKNLLNIIDFVAILPFY--LEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKL 361
Query: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK----------DDHTSS 353
RH VGLR LG TLR S +E LL++FL++G+ IF+ +IY E+ +HT
Sbjct: 362 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQ- 420
Query: 354 LTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYY 413
+IPI +WWA ++MTT+GYGD +P T +G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 421 FKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 246 bits (627), Expect = 4e-65
Identities = 154/480 (32%), Positives = 235/480 (48%), Gaps = 82/480 (17%)
Query: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELC-------------- 57
++ E V LNVGG + +STL P TRL L + L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPP 64
Query: 58 ----------------------------DDYSVADKEYYFDRNPSLFRYVLNFYYTGKLH 89
D+ +E++FDR+P +F YVLN+Y TGKLH
Sbjct: 65 PRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLH 124
Query: 90 VMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEES 149
++C F +E+ +WGI+E ++ CC Y++ ++ D + + D +E
Sbjct: 125 CPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDED 184
Query: 150 SLFEKELEKFDTLRFG----------QLRKKIWIRMENPAYCLSAKLIAISSLSVVLASI 199
L K L D G +L+ ++W E+P +A+ IA +SL +L SI
Sbjct: 185 -LAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSI 243
Query: 200 VAMCVHSMSEFQNEDGEVD----------------DPVLEGVEIACIAWFTGELAVRLAA 243
C+ + F + + DP L VE C+ WFT E VR+
Sbjct: 244 TTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVF 303
Query: 244 APCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKL 303
+P + +F KN LNIIDFV+I+PFY L V S+ +++ ++++R +RI RI KL
Sbjct: 304 SPNKLEFIKNLLNIIDFVAILPFY--LEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKL 361
Query: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK----------DDHTSS 353
RH VGLR LG TLR S +E LL++FL++G+ IF+ +IY E+ +HT
Sbjct: 362 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQ- 420
Query: 354 LTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYY 413
+IPI +WWA ++MTT+GYGD +P T +G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 421 FKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 245 bits (626), Expect = 6e-65
Identities = 147/449 (32%), Positives = 230/449 (51%), Gaps = 55/449 (12%)
Query: 11 GQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFD 70
G + E + +NVGG + +STL P TRL L + DY E++FD
Sbjct: 4 GDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-----DYDPRADEFFFD 58
Query: 71 RNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHE 130
R+P +F ++LN+Y TGKLH ++C + +E+ +WGI+E ++ CC Y++ ++
Sbjct: 59 RHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEA 118
Query: 131 KD------WDQKSHDVSTDSSFEESSLFEKELEKFDTLRFG------------QLRKKIW 172
D D + D D +S E ELE L + + +IW
Sbjct: 119 LDSFGGAPLDNSADDADADGP-GDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIW 177
Query: 173 IRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVD-------------- 218
E+P A+ +A +SL +L SI C+ + F + +
Sbjct: 178 ALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYR 237
Query: 219 ----DPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDT 274
+ L +E C+ WFT E +R+ P + +F KN LNIIDFV+I+PFY L V
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFY--LEVGL 295
Query: 275 KEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVG 334
S+ +++ ++++R +RI RI KL RH VGLR LG TLR S +E LL++FL++G
Sbjct: 296 SGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 355
Query: 335 ISIFSVLIYSVEK----------DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGK 384
+ IF+ +IY E+ +HT +IPI +WWA ++MTT+GYGD +P T +G
Sbjct: 356 VLIFATMIYYAERIGAQPNDPSASEHTH-FKNIPIGFWWAVVTMTTLGYGDMYPQTWSGM 414
Query: 385 LIASTCIICGILVVALPITIIFNKFSKYY 413
L+ + C + G+L +A+P+ +I N F YY
Sbjct: 415 LVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 245 bits (626), Expect = 6e-65
Identities = 147/449 (32%), Positives = 230/449 (51%), Gaps = 55/449 (12%)
Query: 11 GQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFD 70
G + E + +NVGG + +STL P TRL L + DY E++FD
Sbjct: 4 GDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-----DYDPRADEFFFD 58
Query: 71 RNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHE 130
R+P +F ++LN+Y TGKLH ++C + +E+ +WGI+E ++ CC Y++ ++
Sbjct: 59 RHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEA 118
Query: 131 KD------WDQKSHDVSTDSSFEESSLFEKELEKFDTLRFG------------QLRKKIW 172
D D + D D +S E ELE L + + +IW
Sbjct: 119 LDSFGGAPLDNSADDADADGP-GDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIW 177
Query: 173 IRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVD-------------- 218
E+P A+ +A +SL +L SI C+ + F + +
Sbjct: 178 ALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYR 237
Query: 219 ----DPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDT 274
+ L +E C+ WFT E +R+ P + +F KN LNIIDFV+I+PFY L V
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFY--LEVGL 295
Query: 275 KEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVG 334
S+ +++ ++++R +RI RI KL RH VGLR LG TLR S +E LL++FL++G
Sbjct: 296 SGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 355
Query: 335 ISIFSVLIYSVEK----------DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGK 384
+ IF+ +IY E+ +HT +IPI +WWA ++MTT+GYGD +P T +G
Sbjct: 356 VLIFATMIYYAERIGAQPNDPSASEHTH-FKNIPIGFWWAVVTMTTLGYGDMYPQTWSGM 414
Query: 385 LIASTCIICGILVVALPITIIFNKFSKYY 413
L+ + C + G+L +A+P+ +I N F YY
Sbjct: 415 LVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 241 bits (616), Expect = 8e-64
Identities = 147/451 (32%), Positives = 233/451 (51%), Gaps = 51/451 (11%)
Query: 11 GQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTC------HSEEAILELCDDYSVAD 64
G+ E + +NVGG + +STL P TRL L ++ +
Sbjct: 32 GEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGG 91
Query: 65 KEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQER 124
E++FDR+P +F YVLN+Y TGKLH ++C F +E+ +WGI+E ++ CC Y++
Sbjct: 92 CEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQH 151
Query: 125 KEENHEKD-WDQKSHDVSTDSSFEESSLFEKEL--EKFDTLRFGQ-----------LRKK 170
++ D ++ S +E+ E+EL ++ G + +
Sbjct: 152 RDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPR 211
Query: 171 IWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVD------------ 218
+W E+P +A+++A +SL +L SI C+ + F + +
Sbjct: 212 MWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHF 271
Query: 219 ------DPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAV 272
+P+L +E C+ WFT E VR+ P F KN LNIIDFV+I+PFY L V
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFY--LEV 329
Query: 273 DTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLS 332
S+ ++ ++++R +RI RI KL RH VGLR LG TLR S +E LL++FL+
Sbjct: 330 GLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389
Query: 333 VGISIFSVLIYSVEK----------DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLA 382
+G+ IF+ +IY E+ +DHT +IPI +WWA ++MTT+GYGD +P T +
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTD-FKNIPIGFWWAVVTMTTLGYGDMYPKTWS 448
Query: 383 GKLIASTCIICGILVVALPITIIFNKFSKYY 413
G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 449 GMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 241 bits (616), Expect = 8e-64
Identities = 147/451 (32%), Positives = 233/451 (51%), Gaps = 51/451 (11%)
Query: 11 GQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTC------HSEEAILELCDDYSVAD 64
G+ E + +NVGG + +STL P TRL L ++ +
Sbjct: 32 GEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGG 91
Query: 65 KEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQER 124
E++FDR+P +F YVLN+Y TGKLH ++C F +E+ +WGI+E ++ CC Y++
Sbjct: 92 CEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQH 151
Query: 125 KEENHEKD-WDQKSHDVSTDSSFEESSLFEKEL--EKFDTLRFGQ-----------LRKK 170
++ D ++ S +E+ E+EL ++ G + +
Sbjct: 152 RDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPR 211
Query: 171 IWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVD------------ 218
+W E+P +A+++A +SL +L SI C+ + F + +
Sbjct: 212 MWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHF 271
Query: 219 ------DPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAV 272
+P+L +E C+ WFT E VR+ P F KN LNIIDFV+I+PFY L V
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFY--LEV 329
Query: 273 DTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLS 332
S+ ++ ++++R +RI RI KL RH VGLR LG TLR S +E LL++FL+
Sbjct: 330 GLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389
Query: 333 VGISIFSVLIYSVEK----------DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLA 382
+G+ IF+ +IY E+ +DHT +IPI +WWA ++MTT+GYGD +P T +
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTD-FKNIPIGFWWAVVTMTTLGYGDMYPKTWS 448
Query: 383 GKLIASTCIICGILVVALPITIIFNKFSKYY 413
G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 449 GMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 241 bits (616), Expect = 8e-64
Identities = 147/451 (32%), Positives = 233/451 (51%), Gaps = 51/451 (11%)
Query: 11 GQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTC------HSEEAILELCDDYSVAD 64
G+ E + +NVGG + +STL P TRL L ++ +
Sbjct: 32 GEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGG 91
Query: 65 KEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQER 124
E++FDR+P +F YVLN+Y TGKLH ++C F +E+ +WGI+E ++ CC Y++
Sbjct: 92 CEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQH 151
Query: 125 KEENHEKD-WDQKSHDVSTDSSFEESSLFEKEL--EKFDTLRFGQ-----------LRKK 170
++ D ++ S +E+ E+EL ++ G + +
Sbjct: 152 RDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPR 211
Query: 171 IWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVD------------ 218
+W E+P +A+++A +SL +L SI C+ + F + +
Sbjct: 212 MWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHF 271
Query: 219 ------DPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAV 272
+P+L +E C+ WFT E VR+ P F KN LNIIDFV+I+PFY L V
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFY--LEV 329
Query: 273 DTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLS 332
S+ ++ ++++R +RI RI KL RH VGLR LG TLR S +E LL++FL+
Sbjct: 330 GLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389
Query: 333 VGISIFSVLIYSVEK----------DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLA 382
+G+ IF+ +IY E+ +DHT +IPI +WWA ++MTT+GYGD +P T +
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTD-FKNIPIGFWWAVVTMTTLGYGDMYPKTWS 448
Query: 383 GKLIASTCIICGILVVALPITIIFNKFSKYY 413
G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 449 GMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 239 bits (609), Expect = 5e-63
Identities = 139/420 (33%), Positives = 230/420 (54%), Gaps = 39/420 (9%)
Query: 9 RPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYY 68
+ + +E++ +NV G + ++TL R+P T LG SE+ Y EY+
Sbjct: 34 KASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGS-----SEKEFF-----YDADSGEYF 83
Query: 69 FDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEEN 128
FDR+P +FR+VLNFY TG+LH + C+ +F +E+ ++G+ + CC Y++RK+EN
Sbjct: 84 FDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKEN 143
Query: 129 HEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPA--------Y 180
E+ + + + + D + LR+++W ENP Y
Sbjct: 144 AERLAEDEEAEQAGDGPALPAG--------------SSLRQRLWRAFENPHTSTAALVFY 189
Query: 181 CLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVR 240
++ IA+S ++ V+ +I S + GE ++ AC+ FTGE +R
Sbjct: 190 YVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLR 249
Query: 241 LAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRI 300
L AAP + +F ++ +++ID V+I+P+Y L V ++ S G V LR+ R+FRI
Sbjct: 250 LFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVS------GAFVT-LRVFRVFRI 302
Query: 301 LKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPIC 360
K +RHS GLR LG TL+ E+G LL L++ I IF+ +++ EK + ++ TSIP
Sbjct: 303 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAA 362
Query: 361 WWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDID 420
+W+ ++MTT+GYGD P T+AGK+ S C + G+LV+ALP+ +I + FS+ Y + + D
Sbjct: 363 FWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD 422
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 236 bits (603), Expect = 3e-62
Identities = 144/429 (33%), Positives = 227/429 (52%), Gaps = 44/429 (10%)
Query: 9 RPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYY 68
R + L+ LNV G + Q TL R+P T LG SE Y ++Y+
Sbjct: 35 RKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGS-----SERDFF-----YHPETQQYF 84
Query: 69 FDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEEN 128
FDR+P +FR++LNFY TGKLH C+ ++ +E+ ++G+ I CC Y++R+ EN
Sbjct: 85 FDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRREN 144
Query: 129 HEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPA--------Y 180
E+ D D + +S+ + R+++W ENP Y
Sbjct: 145 AERLQDDADTDTAGESALPTMTA----------------RQRVWRAFENPHTSTMALVFY 188
Query: 181 CLSAKLIAISSLSVVLASIVAMCVHSMSEFQNED-GEVDDPVLEGVEIACIAWFTGELAV 239
++ IA+S ++ V+ ++ C S + GE ++ AC+ FT E +
Sbjct: 189 YVTGFFIAVSVIANVVETVP--CGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLL 246
Query: 240 RLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFR 299
RLAAAP + +F ++ ++IID V+I+P+Y L + E+ S G V LR+ R+FR
Sbjct: 247 RLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVS------GAFVT-LRVFRVFR 299
Query: 300 ILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPI 359
I K +RHS GLR LG TL+ E+G LL L++ I IF+ +++ EK S TSIP
Sbjct: 300 IFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPA 359
Query: 360 CWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDI 419
+W+ ++MTT+GYGD P T+AGK+ S C + G+LV+ALP+ +I + FS+ Y + +
Sbjct: 360 AFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRA 419
Query: 420 DVDQCSEDA 428
D + + A
Sbjct: 420 DKRRAQKKA 428
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 236 bits (601), Expect = 5e-62
Identities = 147/425 (34%), Positives = 225/425 (52%), Gaps = 44/425 (10%)
Query: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDR 71
+ +EL+ LNV G + ++TL R+P T LG +E+ ++ KEY+FDR
Sbjct: 37 RQDELIVLNVSGRRFQTWRTTLERYPDTLLGS-----TEKEFF-----FNEDTKEYFFDR 86
Query: 72 NPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEK 131
+P +FR VLNFY TGKLH C+ ++ E+ ++GI I CC Y++RK EN E+
Sbjct: 87 DPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAER 146
Query: 132 DWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPA--------YCLS 183
D E E +L F R+ +W ENP Y ++
Sbjct: 147 LMDDNDS--------------ENNQESMPSLSF---RQTMWRAFENPHTSTLALVFYYVT 189
Query: 184 AKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAA 243
IA+S ++ V+ ++ V E GE ++ AC+ FT E +RL A
Sbjct: 190 GFFIAVSVITNVVETVPCGTVPGSKELPC--GERYSVAFFCLDTACVMIFTVEYLLRLFA 247
Query: 244 APCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKL 303
AP + +F ++ ++IID V+I+P+Y L + E+ S G V LR+ R+FRI K
Sbjct: 248 APSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVS------GAFVT-LRVFRVFRIFKF 300
Query: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWW 363
+RHS GLR LG TL+ E+G LL L++ I IF+ +++ EK S TSIP +W+
Sbjct: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
Query: 364 ATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQ 423
++MTT+GYGD P T+AGK+ S C + G+LV+ALP+ +I + FS+ Y + + D +
Sbjct: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
Query: 424 CSEDA 428
+ A
Sbjct: 421 AQKKA 425
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 236 bits (601), Expect = 5e-62
Identities = 147/425 (34%), Positives = 225/425 (52%), Gaps = 44/425 (10%)
Query: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDR 71
+ +EL+ LNV G + ++TL R+P T LG +E+ ++ KEY+FDR
Sbjct: 37 RQDELIVLNVSGRRFQTWRTTLERYPDTLLGS-----TEKEFF-----FNEDTKEYFFDR 86
Query: 72 NPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEK 131
+P +FR VLNFY TGKLH C+ ++ E+ ++GI I CC Y++RK EN E+
Sbjct: 87 DPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAER 146
Query: 132 DWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPA--------YCLS 183
D E E +L F R+ +W ENP Y ++
Sbjct: 147 LMDDNDS--------------ENNQESMPSLSF---RQTMWRAFENPHTSTLALVFYYVT 189
Query: 184 AKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAA 243
IA+S ++ V+ ++ V E GE ++ AC+ FT E +RL A
Sbjct: 190 GFFIAVSVITNVVETVPCGTVPGSKELPC--GERYSVAFFCLDTACVMIFTVEYLLRLFA 247
Query: 244 APCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKL 303
AP + +F ++ ++IID V+I+P+Y L + E+ S G V LR+ R+FRI K
Sbjct: 248 APSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVS------GAFVT-LRVFRVFRIFKF 300
Query: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWW 363
+RHS GLR LG TL+ E+G LL L++ I IF+ +++ EK S TSIP +W+
Sbjct: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
Query: 364 ATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQ 423
++MTT+GYGD P T+AGK+ S C + G+LV+ALP+ +I + FS+ Y + + D +
Sbjct: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
Query: 424 CSEDA 428
+ A
Sbjct: 421 AQKKA 425
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 233 bits (593), Expect = 4e-61
Identities = 146/470 (31%), Positives = 229/470 (48%), Gaps = 74/470 (15%)
Query: 11 GQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFD 70
G D + +NVGG + +STL P TRL L EA DY E++FD
Sbjct: 84 GGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLT---EPEAAARF--DYDPGADEFFFD 138
Query: 71 RNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHE 130
R+P +F YVLN+Y TGKLH ++C F +E+ +WGI+E +++CC Y++ ++
Sbjct: 139 RHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEA 198
Query: 131 KDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQL----------------------- 167
D + ++ + + L+ G L
Sbjct: 199 LDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPP 258
Query: 168 --------------RKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNE 213
+ ++W E+P +A+ +A +SL +L SI C+ + F +
Sbjct: 259 GGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHI 318
Query: 214 DGEV---------------------DDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWK 252
+ +P L VE C+ WFT E +R+ P + +F K
Sbjct: 319 SNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLK 378
Query: 253 NPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRS 312
+ LNIID V+I+PFY L V S+ +++ ++++R +RI RI KL RH VGLR
Sbjct: 379 SSLNIIDCVAILPFY--LEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRV 436
Query: 313 LGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK-----DDHTSS----LTSIPICWWW 363
LG TLR S +E LL++FL++G+ IF+ +IY E+ DD S +IPI +WW
Sbjct: 437 LGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWW 496
Query: 364 ATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYY 413
A ++MTT+GYGD +P T +G L+ + C + G+L +A+P+ +I N F YY
Sbjct: 497 AVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 231 bits (588), Expect = 1e-60
Identities = 143/431 (33%), Positives = 220/431 (51%), Gaps = 69/431 (16%)
Query: 15 ELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPS 74
E V +N+ G + TL +FP T LG + + D EY+FDRN
Sbjct: 104 ERVVINISGLRFETQLKTLCQFPETLLG------DPKRRMRYFDPLR---NEYFFDRNRP 154
Query: 75 LFRYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDW 133
F +L +Y +G ++ + + F +EI ++ + E E EK
Sbjct: 155 SFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGE----------------EAMEK-- 196
Query: 134 DQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLS 193
F E F +E E+ L ++++W+ E P A+ IAI S+
Sbjct: 197 ------------FREDEGFLREEER--PLPRRDFQRQVWLLFEYPESSGPARGIAIVSVL 242
Query: 194 VVLASIVAMCVHSMSEFQNED-------------------------GEVDDPVLEGVEIA 228
V+L SIV C+ ++ EF++E DP VE
Sbjct: 243 VILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFV-VETL 301
Query: 229 CIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMG-K 287
CI WF+ EL VR A P + F +N +N+ID V+IIP++ TL + E + + M
Sbjct: 302 CIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLA 361
Query: 288 VVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK 347
+++++RL+R+FRI KL+RHS GL+ LG TL+ S E+GLL+ FL +G+ +FS +Y E
Sbjct: 362 ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA 421
Query: 348 DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFN 407
DD TS +SIP +WWA ++MTTVGYGD HPVT+ GK++ S C I G+L +ALP+ +I +
Sbjct: 422 DDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVS 481
Query: 408 KFSKYYQKQKD 418
F+ +Y ++ +
Sbjct: 482 NFNYFYHRETE 492
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 230 bits (587), Expect = 2e-60
Identities = 156/500 (31%), Positives = 251/500 (50%), Gaps = 71/500 (14%)
Query: 15 ELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPS 74
E V +N+ G + TL +FP+T LG + + + D EY+FDRN
Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLG------NPKKRMRYFDPLR---NEYFFDRNRP 87
Query: 75 LFRYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDW 133
F +L +Y +G +L + + F +EI+++ + E ++ R++E K+
Sbjct: 88 SFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKF-------REDEGFIKE- 139
Query: 134 DQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLS 193
EE L EKE ++ ++W+ E P A++IAI S+
Sbjct: 140 -------------EERPLPEKEYQR-----------QVWLLFEYPESSGPARVIAIVSVM 175
Query: 194 VVLASIVAMCVHSMSEFQNEDG------EVD------------DPVLEGVEIACIAWFTG 235
V+L SIV C+ ++ E +++ +D DP VE CI WF+
Sbjct: 176 VILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFI-VETLCIIWFSF 234
Query: 236 ELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGK---VVQIL 292
EL VR A P + F+KN +N ID V+IIP++ TL + E+E +++++
Sbjct: 235 ELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVI 294
Query: 293 RLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTS 352
RL+R+FRI KL+RHS GL+ LG TL+ S E+GLL+ FL +G+ +FS +Y E ++ S
Sbjct: 295 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES 354
Query: 353 SLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKY 412
+SIP +WWA +SMTTVGYGD +PVT+ GK++ S C I G+L +ALP+ +I + F+ +
Sbjct: 355 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 414
Query: 413 YQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASS 472
Y ++ + E+ + H D R + S S + D +++ A
Sbjct: 415 YHRETE------GEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHY 468
Query: 473 IEDNEDICN-TTSLENCTAK 491
+ N N TT+ +NC K
Sbjct: 469 RQVNIRTANCTTANQNCVNK 488
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 228 bits (582), Expect = 7e-60
Identities = 149/455 (32%), Positives = 228/455 (50%), Gaps = 73/455 (16%)
Query: 15 ELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPS 74
E V +NV G + TL +FP T LG E + D EY+FDRN
Sbjct: 176 ERVVINVSGLRFETQMKTLAQFPETLLG------DPEKRTQYFDPLR---NEYFFDRNRP 226
Query: 75 LFRYVLNFYYT-GKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDW 133
F +L +Y + G+L + F +E++++ + E +
Sbjct: 227 SFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL-------------------- 266
Query: 134 DQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLS 193
F E F +E E+ L + +K+IW+ E P A+ IAI S+
Sbjct: 267 ----------LKFREDEGFVRE-EEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVL 315
Query: 194 VVLASIVAMCVHSMSEFQNE------------DGEVDD---PVLEG------------VE 226
V+L SIV C+ ++ EF+++ G ++D P LE VE
Sbjct: 316 VILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVE 375
Query: 227 IACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEE----SEDI 282
CI WF+ E VR A P Q F+KN +NIID VSI+P++ TL D +++ +
Sbjct: 376 TVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQ 435
Query: 283 ENMG-KVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVL 341
+ M +++I+RL+R+FRI KL+RHS GL+ LG TLR S E+GLL+ FL +G+ +FS
Sbjct: 436 QAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSA 495
Query: 342 IYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALP 401
+Y E D+ T+ SIP +WWA ++MTTVGYGD P+T+ GK++ S C I G+L +ALP
Sbjct: 496 VYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALP 555
Query: 402 ITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELP 436
+ +I + F+ +Y ++ + + C LP
Sbjct: 556 VPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLP 590
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 227 bits (579), Expect = 2e-59
Identities = 145/449 (32%), Positives = 227/449 (50%), Gaps = 71/449 (15%)
Query: 4 GEFFHRPGQDEELVN-------LNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILEL 56
G++ PG + ++N +N+ G + TL +FP T LG E ++
Sbjct: 68 GDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLG------DREKRMQF 121
Query: 57 CDDYSVADKEYYFDRNPSLFRYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDS 115
D EY+FDRN F +L +Y +G K+ + + F EI ++ + +D
Sbjct: 122 FDSMR---NEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQ 178
Query: 116 CCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRM 175
F E F K+ E L + ++ W+
Sbjct: 179 ------------------------------FREDEGFIKDPETL--LPTNDIHRQFWLLF 206
Query: 176 ENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGE---VDDPVLEG-------- 224
E P +A+ +A+ S+ VV+ SI C+ ++ EF+ ED E V DP L
Sbjct: 207 EYPESSSAARAVAVVSVLVVVISITIFCLETLPEFR-EDRELKVVRDPNLNMSKTVLSQT 265
Query: 225 --------VEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVD-TK 275
VE CI WFT EL +R P + F++N +NIID +SIIP++ATL + +
Sbjct: 266 MFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQ 325
Query: 276 EEESEDIENMG-KVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVG 334
E E +NM +++I+RL+R+FRI KL+RHS GL+ LG TL+ S E+GLL+ FL +G
Sbjct: 326 ETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 385
Query: 335 ISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICG 394
+ +FS +Y E D+ S +SIP +WWA ++MTTVGYGD P T GK++ + C I G
Sbjct: 386 VILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAG 445
Query: 395 ILVVALPITIIFNKFSKYYQKQKDIDVDQ 423
+L +ALP+ +I + F+ +Y ++ + + Q
Sbjct: 446 VLTIALPVPVIVSNFNYFYHRETENEEKQ 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,019,084
Number of Sequences: 37866
Number of extensions: 785314
Number of successful extensions: 2849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 2311
Number of HSP's gapped (non-prelim): 387
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.