Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 25952087
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
(613 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25952087 potassium voltage-gated channel, shaker-related subf... 1242 0.0
gi|88758565 potassium voltage-gated channel, shaker-related subf... 636 0.0
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 622 e-178
gi|119395748 potassium voltage-gated channel subfamily A member ... 613 e-175
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 612 e-175
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 609 e-174
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 566 e-161
gi|25952092 potassium voltage-gated channel, shaker-related subf... 552 e-157
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 264 2e-70
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 257 2e-68
gi|163792201 Shaw-related voltage-gated potassium channel protei... 257 2e-68
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 256 6e-68
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 256 6e-68
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 254 1e-67
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 253 5e-67
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 249 4e-66
gi|88758576 Shaw-related voltage-gated potassium channel protein... 246 6e-65
gi|24497462 Shaw-related voltage-gated potassium channel protein... 246 6e-65
gi|24497464 Shaw-related voltage-gated potassium channel protein... 246 6e-65
gi|21217561 Shaw-related voltage-gated potassium channel protein... 238 1e-62
gi|21217563 Shaw-related voltage-gated potassium channel protein... 238 1e-62
gi|24497458 Shaw-related voltage-gated potassium channel protein... 238 1e-62
gi|24497460 Shaw-related voltage-gated potassium channel protein... 233 5e-61
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 222 9e-58
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 219 8e-57
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 218 2e-56
gi|20070166 potassium voltage-gated channel, subfamily F, member... 209 8e-54
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 206 7e-53
gi|19071574 potassium voltage-gated channel, subfamily G, member... 201 2e-51
gi|27436993 potassium voltage-gated channel, subfamily G, member... 199 6e-51
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 1242 bits (3213), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 1 MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA 60
MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
Sbjct: 1 MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA 60
Query: 61 DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ 120
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
Sbjct: 61 DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ 120
Query: 121 RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ 180
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
Sbjct: 121 RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ 180
Query: 181 SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF 240
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
Sbjct: 181 SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF 240
Query: 241 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG 300
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
Sbjct: 241 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG 300
Query: 301 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII 360
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
Sbjct: 301 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII 360
Query: 361 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL 420
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
Sbjct: 361 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL 420
Query: 421 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT 480
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
Sbjct: 421 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT 480
Query: 481 VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG 540
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
Sbjct: 481 VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG 540
Query: 541 TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL 600
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
Sbjct: 541 TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL 600
Query: 601 YALCLDTSRETDL 613
YALCLDTSRETDL
Sbjct: 601 YALCLDTSRETDL 613
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 636 bits (1641), Expect = 0.0
Identities = 345/509 (67%), Positives = 387/509 (76%), Gaps = 40/509 (7%)
Query: 37 PPTAG-LSDGPKEPAPKGRGAQRDADSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPED 95
PP+A + P+ PA G GA + G P G R LPP +P PE
Sbjct: 13 PPSARHRAHPPQRPASSG-GAHTLVNHGYAE----PAAG-RELPPDMTVVPGDHLLEPEV 66
Query: 96 EEEEGDPGLGTVED-------------QALGTASLHHQRVHINISGLRFETQLGTLAQFP 142
+ G P G A G +RV INISGLRFETQL TL QFP
Sbjct: 67 ADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFP 126
Query: 143 NTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRF 202
TLLGDP +R+RYFDPLRNEYFFDRNRPSFD ILYYYQSGGR+RRPVNV +D+F++EIRF
Sbjct: 127 ETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRF 186
Query: 203 YQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILI 262
YQLG+EAME+FREDEGF++EEE+PLPR +FQRQVWL+FEYPESSG AR IAIVSVLVILI
Sbjct: 187 YQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILI 246
Query: 263 SIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLAD 322
SI+ FCLETLPEFRDE++ +P + Q A G + SG A S + +D
Sbjct: 247 SIVIFCLETLPEFRDEKD---YPASTSQDSFEAAGNSTSGSRAGAS----------SFSD 293
Query: 323 PFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPG 382
PFF+VET C+IWF+FELLVRFFACPSKA FSRNIMN+ID+VAI PYFITLGTELAE+Q
Sbjct: 294 PFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ-- 351
Query: 383 GGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLF 442
NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILG+TL+ASMRELGLLIFFLF
Sbjct: 352 -----GNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406
Query: 443 IGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAI 502
IGVILFSSAVYFAEAD+ + FSSIPDAFWWAVVTMTTVGYGDM P+T+GGKIVGSLCAI
Sbjct: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466
Query: 503 AGVLTIALPVPVIVSNFNYFYHRETDHEE 531
AGVLTIALPVPVIVSNFNYFYHRET+ EE
Sbjct: 467 AGVLTIALPVPVIVSNFNYFYHRETEGEE 495
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 622 bits (1605), Expect = e-178
Identities = 321/415 (77%), Positives = 348/415 (83%), Gaps = 21/415 (5%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYY 179
+RV INISGLRFETQL TLAQFP TLLGDP KR+RYFDPLRNEYFFDRNRPSFD ILYYY
Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY 92
Query: 180 QSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLI 239
QSGGRLRRPVNV LD+F++EIRFY+LG+EAME FREDEG+IKEEE+PLP NEFQRQVWL+
Sbjct: 93 QSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLL 152
Query: 240 FEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGAN 299
FEYPESSG AR IAIVSV+VILISI++FCLETLP FRDE E +
Sbjct: 153 FEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE----------------DMH 196
Query: 300 GSGV-MAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMN 358
GSGV S T+ + DPFFIVET C+IWF+FE LVRFFACPSKAGF NIMN
Sbjct: 197 GSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMN 256
Query: 359 IIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK 418
IID+VAI PYFITLGTELAE+ Q GQQAMSLAILRVIRLVRVFRIFKLSRHSK
Sbjct: 257 IIDIVAIIPYFITLGTELAEKPE----DAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSK 312
Query: 419 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTM 478
GLQILG+TL+ASMRELGLLIFFLFIGVILFSSAVYFAEAD + + F SIPDAFWWAVV+M
Sbjct: 313 GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSM 372
Query: 479 TTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPA 533
TTVGYGDM P T+GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET+ EE A
Sbjct: 373 TTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQA 427
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 613 bits (1581), Expect = e-175
Identities = 311/416 (74%), Positives = 348/416 (83%), Gaps = 25/416 (6%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYY 179
+RV INISGLRFETQL TLAQFPNTLLG+P KR+RYFDPLRNEYFFDRNRPSFD ILYYY
Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY 96
Query: 180 QSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLI 239
QSGGRLRRPVNV LD+F++EI+FY+LG+EAME+FREDEGFIKEEE+PLP E+QRQVWL+
Sbjct: 97 QSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLL 156
Query: 240 FEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGAN 299
FEYPESSG AR IAIVSV+VILISI+ FCLETLPE +D+++
Sbjct: 157 FEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDF------------------ 198
Query: 300 GSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNI 359
+G + TV DPFFIVET C+IWF+FEL+VRFFACPSK F +NIMN
Sbjct: 199 -TGTVHRIDNTTVI-YNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNF 256
Query: 360 IDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 419
ID+VAI PYFITLGTE+AEQ+ G Q G+QA SLAILRVIRLVRVFRIFKLSRHSKG
Sbjct: 257 IDIVAIIPYFITLGTEIAEQE-----GNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKG 311
Query: 420 LQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMT 479
LQILG+TL+ASMRELGLLIFFLFIGVILFSSAVYFAEA+ +HFSSIPDAFWWAVV+MT
Sbjct: 312 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMT 371
Query: 480 TVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVL 535
TVGYGDM P+T+GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET+ EE A L
Sbjct: 372 TVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQL 427
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 612 bits (1579), Expect = e-175
Identities = 324/460 (70%), Positives = 357/460 (77%), Gaps = 25/460 (5%)
Query: 93 PEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKR 152
PE E+++ G + G +R+ INISGLRFETQL TL+ FP+TLLGDP +R
Sbjct: 18 PEGEQQDA----GDFPEAGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRR 73
Query: 153 LRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMER 212
+R+FDPLRNEYFFDRNRPSFD ILYYYQSGGRLRRPVNV LD+F +EIRFYQLGDEA+
Sbjct: 74 VRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAA 133
Query: 213 FREDEGFIKE---EEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCL 269
FREDEG + E +EKPLP FQRQVWL+FEYPESSG AR IAIVSVLVILISI+ FCL
Sbjct: 134 FREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCL 193
Query: 270 ETLPEFRDERE------LLRHPPAPHQPPAPAPGANGS---------GVMAPPSGPTVAP 314
ETLP+FR + + R P + S G M +++
Sbjct: 194 ETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLST 253
Query: 315 LLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGT 374
L DPFF+VET C++WFTFELLVRF ACPSK F RNIMNIID+VAIFPYFITLGT
Sbjct: 254 LGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGT 313
Query: 375 ELA---EQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASM 431
EL EQQP GGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASM
Sbjct: 314 ELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASM 373
Query: 432 RELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITV 491
RELGLLIFFLFIGVILFSSAVYFAEAD+ + F SIPDAFWWAVVTMTTVGYGDM P+TV
Sbjct: 374 RELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTV 433
Query: 492 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEE 531
GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET+ EE
Sbjct: 434 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEE 473
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 609 bits (1571), Expect = e-174
Identities = 321/473 (67%), Positives = 370/473 (78%), Gaps = 19/473 (4%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYY 179
+RV IN+SGLRFETQ+ TLAQFP TLLGDP KR +YFDPLRNEYFFDRNRPSFD ILYYY
Sbjct: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
Query: 180 QSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEE-KPLPRNEFQRQVWL 238
QSGGRL+RPVNV D+F +E++FYQLG+EA+ +FREDEGF++EEE + LP NEF++Q+WL
Sbjct: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWL 295
Query: 239 IFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGA 298
+FEYPESS AR IAIVSVLVILISI+ FCLETLPEFRD+R+L+ A + G
Sbjct: 296 LFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVM---------ALSAGG 346
Query: 299 NGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMN 358
+G G++ S P + DPFFIVET C++WF+FE +VR FACPS+A F +NIMN
Sbjct: 347 HG-GLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMN 405
Query: 359 IIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK 418
IID+V+I PYFITLGT+LA+QQ GGG GQ QQAMS AILR+IRLVRVFRIFKLSRHSK
Sbjct: 406 IIDIVSILPYFITLGTDLAQQQ--GGGNGQQ-QQAMSFAILRIIRLVRVFRIFKLSRHSK 462
Query: 419 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTM 478
GLQILG TL+ASMRELGLLIFFLFIGVILFSSAVYFAEAD THF SIPDAFWWAVVTM
Sbjct: 463 GLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTM 522
Query: 479 TTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEE 538
TTVGYGDM+PITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET++EE L +
Sbjct: 523 TTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQ- 581
Query: 539 QGTQSQGPGLDRGVQRKV-SGSRGSFCKAGGTLENADSARRGSCPL-EKCNVK 589
P L + +K S + S LE + + C EKC K
Sbjct: 582 --NAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCAKEEKCQGK 632
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 567 bits (1460), Expect = e-161
Identities = 286/414 (69%), Positives = 334/414 (80%), Gaps = 27/414 (6%)
Query: 119 HQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYY 178
+QRV INI+GLRFETQL TL+QFP TLLGD KR+++FD +RNEYFFDRNRPSFDGILYY
Sbjct: 85 NQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYY 144
Query: 179 YQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWL 238
YQSGG++RRP NV +D+FADEI FY+LG EAM++FREDEGFIK+ E LP N+ RQ WL
Sbjct: 145 YQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWL 204
Query: 239 IFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGA 298
+FEYPESS +ARA+A+VSVLV++ISI FCLETLPEFR++REL
Sbjct: 205 LFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDREL----------------- 247
Query: 299 NGSGVMAPPSGPTVAPLLPRTL-ADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIM 357
V+ P+ +L +T+ DPFF+VE+TC++WFTFEL++RF CPSK F RNIM
Sbjct: 248 ---KVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIM 304
Query: 358 NIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHS 417
NIID+++I PYF TL TEL ++ + QQ MSLAILR+IRLVRVFRIFKLSRHS
Sbjct: 305 NIIDIISIIPYFATLITELVQETE------PSAQQNMSLAILRIIRLVRVFRIFKLSRHS 358
Query: 418 KGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVT 477
KGLQILG+TL+ASMRELGLLIFFLFIGVILFSSAVYFAE D +HFSSIPD FWWAVVT
Sbjct: 359 KGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVT 418
Query: 478 MTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEE 531
MTTVGYGDM P T GGKIVG+LCAIAGVLTIALPVPVIVSNFNYFYHRET++EE
Sbjct: 419 MTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 472
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 552 bits (1423), Expect = e-157
Identities = 282/412 (68%), Positives = 330/412 (80%), Gaps = 15/412 (3%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYY 179
+R+ +N++GLRFET+ TL +FP+TLLGDPA+R R++D R EYFFDR+RPSFD +LYYY
Sbjct: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
Query: 180 QSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLI 239
QSGGRLRRP +V LDVF +E+ FY LG A+ R REDEG E+PLPR F RQ+WL+
Sbjct: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLL 132
Query: 240 FEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGAN 299
FE+PESS +AR +A+VSVLVIL+SI+ FCLETLP+FRD+R+ A P PAP N
Sbjct: 133 FEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAP-LN 191
Query: 300 GSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNI 359
GS M P P P LP DPFF+VET C+ WF+FELLVR CPSKA F +N+MN+
Sbjct: 192 GSSQM--PGNP---PRLP--FNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNL 244
Query: 360 IDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 419
ID VAI PYF+ LGTELA Q+ G QQAMSLAILRVIRLVRVFRIFKLSRHSKG
Sbjct: 245 IDFVAILPYFVALGTELARQRGVG-------QQAMSLAILRVIRLVRVFRIFKLSRHSKG 297
Query: 420 LQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMT 479
LQILG+TL+ASMRELGLLIFFLFIGV+LFSSAVYFAE D +HF+SIP++FWWAVVTMT
Sbjct: 298 LQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMT 357
Query: 480 TVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEE 531
TVGYGDM P+TVGGKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRET+ EE
Sbjct: 358 TVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 264 bits (675), Expect = 2e-70
Identities = 163/420 (38%), Positives = 229/420 (54%), Gaps = 64/420 (15%)
Query: 124 INISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGG 183
+N+SG RFET TL ++P+TLLG K ++D EYFFDR+ F +L +Y++G
Sbjct: 44 VNVSGRRFETWKNTLDRYPDTLLGSSEKEF-FYDADSGEYFFDRDPDMFRHVLNFYRTG- 101
Query: 184 RLRRPVNVSLDVFADEIRFYQL-----GDEAMERFR-----------EDEGFIKEEEKP- 226
RL P + F +E+ FY L GD +E +R EDE + + P
Sbjct: 102 RLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPA 161
Query: 227 LPRNEFQRQ-VWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHP 285
LP RQ +W FE P +S +A V+ I +S+I +ET+P R R
Sbjct: 162 LPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQ 221
Query: 286 PAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFA 345
P + P FF ++T CV+ FT E L+R FA
Sbjct: 222 PCGERFP-----------------------------QAFFCMDTACVLIFTGEYLLRLFA 252
Query: 346 CPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLV 405
PS+ F R++M++IDVVAI PY+I L + G +R+
Sbjct: 253 APSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGA---------------FVTLRVF 297
Query: 406 RVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFS 465
RVFRIFK SRHS+GL+ILG TL++ ELG L+F L + +I+F++ +++AE T+F+
Sbjct: 298 RVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFT 357
Query: 466 SIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR 525
SIP AFW+ +VTMTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 358 SIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 417
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 257 bits (657), Expect = 2e-68
Identities = 172/472 (36%), Positives = 244/472 (51%), Gaps = 104/472 (22%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLG---DPAKRLRY-FDPLRNEYFFDRNRPSFDGI 175
+R+ IN+ G R +T TL P T L +P + +DP +E+FFDR+ F I
Sbjct: 8 ERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHI 67
Query: 176 LYYYQSGGRLRRPVNVSLDVFADEIRFYQL------------------GDEAMERFRE-- 215
L YY++G +L P +V ++ +E+ F+ + +EA++ F
Sbjct: 68 LNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAP 126
Query: 216 --------------DEGFIKEEEKPLPR---------------NEFQRQVWLIFEYPESS 246
D G ++E + R +Q ++W +FE P SS
Sbjct: 127 LDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSS 186
Query: 247 GSARAIAIVSVLVILISIITFCLETLPEF-----RDERELLRHPPAPHQPPAPAPGANGS 301
AR +A S+ IL+SI TFCLET F + E E +R NG+
Sbjct: 187 RYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVR---------------NGT 231
Query: 302 GVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIID 361
V T A L +E CV+WFTFE L+R CP+K F +N +NIID
Sbjct: 232 QVRYYREAETEAFLT---------YIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIID 282
Query: 362 VVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVIRLVRVFRIFKLSRHSKGL 420
VAI P+++ +G G + + A L LRV+R VR+ RIFKL+RH GL
Sbjct: 283 FVAILPFYLEVGLS-----------GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGL 331
Query: 421 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE---------ADNQGTHFSSIPDAF 471
++LG TL+AS E LLI FL +GV++F++ +Y+AE + ++ THF +IP F
Sbjct: 332 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGF 391
Query: 472 WWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 523
WWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 392 WWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 257 bits (657), Expect = 2e-68
Identities = 172/472 (36%), Positives = 244/472 (51%), Gaps = 104/472 (22%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLG---DPAKRLRY-FDPLRNEYFFDRNRPSFDGI 175
+R+ IN+ G R +T TL P T L +P + +DP +E+FFDR+ F I
Sbjct: 8 ERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHI 67
Query: 176 LYYYQSGGRLRRPVNVSLDVFADEIRFYQL------------------GDEAMERFRE-- 215
L YY++G +L P +V ++ +E+ F+ + +EA++ F
Sbjct: 68 LNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAP 126
Query: 216 --------------DEGFIKEEEKPLPR---------------NEFQRQVWLIFEYPESS 246
D G ++E + R +Q ++W +FE P SS
Sbjct: 127 LDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSS 186
Query: 247 GSARAIAIVSVLVILISIITFCLETLPEF-----RDERELLRHPPAPHQPPAPAPGANGS 301
AR +A S+ IL+SI TFCLET F + E E +R NG+
Sbjct: 187 RYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVR---------------NGT 231
Query: 302 GVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIID 361
V T A L +E CV+WFTFE L+R CP+K F +N +NIID
Sbjct: 232 QVRYYREAETEAFLT---------YIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIID 282
Query: 362 VVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVIRLVRVFRIFKLSRHSKGL 420
VAI P+++ +G G + + A L LRV+R VR+ RIFKL+RH GL
Sbjct: 283 FVAILPFYLEVGLS-----------GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGL 331
Query: 421 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE---------ADNQGTHFSSIPDAF 471
++LG TL+AS E LLI FL +GV++F++ +Y+AE + ++ THF +IP F
Sbjct: 332 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGF 391
Query: 472 WWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 523
WWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 392 WWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 256 bits (653), Expect = 6e-68
Identities = 155/417 (37%), Positives = 230/417 (55%), Gaps = 63/417 (15%)
Query: 124 INISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGG 183
+N+SG RF+T TL ++P+TLLG K +F+ EYFFDR+ F +L +Y++G
Sbjct: 44 LNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFYRTG- 101
Query: 184 RLRRPVNVSLDVFADEIRFYQL-----GDEAMERFRE----------DEGFIKEEEKPLP 228
+L P + + DE+ FY + GD E +++ D+ + ++ +P
Sbjct: 102 KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMP 161
Query: 229 RNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAP 288
F++ +W FE P +S A V+ I +S+IT +ET+P
Sbjct: 162 SLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP--------------- 206
Query: 289 HQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPS 348
PG+ P G + FF ++T CV+ FT E L+R FA PS
Sbjct: 207 ---CGTVPGSKEL-----PCGERYSVA--------FFCLDTACVMIFTVEYLLRLFAAPS 250
Query: 349 KAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVF 408
+ F R++M+IIDVVAI PY+I L E G +R+ RVF
Sbjct: 251 RYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGA---------------FVTLRVFRVF 295
Query: 409 RIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIP 468
RIFK SRHS+GL+ILG TL++ ELG L+F L + +I+F++ +++AE + + F+SIP
Sbjct: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIP 355
Query: 469 DAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR 525
+FW+ +VTMTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 356 ASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 412
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 256 bits (653), Expect = 6e-68
Identities = 155/417 (37%), Positives = 230/417 (55%), Gaps = 63/417 (15%)
Query: 124 INISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGG 183
+N+SG RF+T TL ++P+TLLG K +F+ EYFFDR+ F +L +Y++G
Sbjct: 44 LNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFYRTG- 101
Query: 184 RLRRPVNVSLDVFADEIRFYQL-----GDEAMERFRE----------DEGFIKEEEKPLP 228
+L P + + DE+ FY + GD E +++ D+ + ++ +P
Sbjct: 102 KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMP 161
Query: 229 RNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAP 288
F++ +W FE P +S A V+ I +S+IT +ET+P
Sbjct: 162 SLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP--------------- 206
Query: 289 HQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPS 348
PG+ P G + FF ++T CV+ FT E L+R FA PS
Sbjct: 207 ---CGTVPGSKEL-----PCGERYSVA--------FFCLDTACVMIFTVEYLLRLFAAPS 250
Query: 349 KAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVF 408
+ F R++M+IIDVVAI PY+I L E G +R+ RVF
Sbjct: 251 RYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGA---------------FVTLRVFRVF 295
Query: 409 RIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIP 468
RIFK SRHS+GL+ILG TL++ ELG L+F L + +I+F++ +++AE + + F+SIP
Sbjct: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIP 355
Query: 469 DAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR 525
+FW+ +VTMTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 356 ASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 412
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 254 bits (650), Expect = 1e-67
Identities = 156/418 (37%), Positives = 232/418 (55%), Gaps = 63/418 (15%)
Query: 124 INISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGG 183
+N+SG RF+T TL ++P+TLLG ++R ++ P +YFFDR+ F IL +Y++G
Sbjct: 45 LNVSGTRFQTWQDTLERYPDTLLGS-SERDFFYHPETQQYFFDRDPDIFRHILNFYRTG- 102
Query: 184 RLRRPVNVSLDVFADEIRFYQL-----GD-----------EAMERFREDEGFIKEEEKPL 227
+L P + + + +E+ F+ L GD E ER ++D E L
Sbjct: 103 KLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESAL 162
Query: 228 PRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPA 287
P +++VW FE P +S A V+ I +S+I +ET+P
Sbjct: 163 PTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVP-------------- 208
Query: 288 PHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACP 347
G++ + P G A FF ++T CV+ FT E L+R A P
Sbjct: 209 --------CGSSPGHIKELPCGERYAVA--------FFCLDTACVMIFTVEYLLRLAAAP 252
Query: 348 SKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRV 407
S+ F R++M+IIDVVAI PY+I G + + + G +R+ RV
Sbjct: 253 SRYRFVRSVMSIIDVVAILPYYI--GLVMTDNEDVSGA-------------FVTLRVFRV 297
Query: 408 FRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSI 467
FRIFK SRHS+GL+ILG TL++ ELG L+F L + +I+F++ +++AE + + F+SI
Sbjct: 298 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSI 357
Query: 468 PDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR 525
P AFW+ +VTMTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 358 PAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 415
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 253 bits (645), Expect = 5e-67
Identities = 173/493 (35%), Positives = 259/493 (52%), Gaps = 81/493 (16%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLGD------PAKRLRYFDPLR---NEYFFDRNRP 170
+RV IN+ GL E TL + P T LG L D NEYFFDR+
Sbjct: 35 RRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPG 94
Query: 171 SFDGILYYYQSGGRLRRPVNVSLDVFADEI----------------RFYQLGDEAMERFR 214
+F IL +Y++G +L + F E+ R++Q ++ E R
Sbjct: 95 AFTSILNFYRTG-KLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELR 153
Query: 215 EDEGFIKEEEKPLPRN----EFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLE 270
+ ++E E N + ++++W + E P SS +A+ +AIVS+L I++S I L
Sbjct: 154 REAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLN 213
Query: 271 TLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETT 330
TLPE ++ E + N + +A VE
Sbjct: 214 TLPELQETDEFGQ--------------LNDNRQLAH--------------------VEAV 239
Query: 331 CVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNG 390
C+ WFT E L+RF + P+K F + +N+ID++AI PY++T+ L E ++
Sbjct: 240 CIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIF--LTESN-------KSV 290
Query: 391 QQAMSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFS 449
Q ++ ++++ R++R+ RI KL+RHS GLQ LG TL+ S ELGLLI FL +G+++FS
Sbjct: 291 LQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFS 350
Query: 450 SAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIA 509
S V+FAE D T F+SIP +FWWA +TMTTVGYGD+ P T+ GKIVG LC IAGVL IA
Sbjct: 351 SLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIA 410
Query: 510 LPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRG------SF 563
LP+P+IV+NF+ FY +E +E A+ + E +++ G + K + +R +
Sbjct: 411 LPIPIIVNNFSEFY-KEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDVAV 469
Query: 564 CKAGGTLENADSA 576
KAG + DSA
Sbjct: 470 EKAGESANTKDSA 482
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 249 bits (637), Expect = 4e-66
Identities = 163/450 (36%), Positives = 239/450 (53%), Gaps = 77/450 (17%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLR----------NEYFFDRNR 169
+RV +N+ GL E TL + P T LG + D L NEYFFDR+
Sbjct: 31 RRVRLNVGGLAHEVLWRTLDRLPRTRLGK-LRDCNTHDSLLEVCDDYSLDDNEYFFDRHP 89
Query: 170 PSFDGILYYYQSGGRLRRPVNVSLDVFADEI----------------RFYQLGDEAMERF 213
+F IL +Y++G RL + F+ E+ R++Q ++ E
Sbjct: 90 GAFTSILNFYRTG-RLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEEL 148
Query: 214 REDEGFIKEEEKPLPRN----EFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCL 269
+ + ++E E N E ++++W + E P SS +A+ +AI+S++ I++S I L
Sbjct: 149 KREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIALSL 208
Query: 270 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVET 329
TLPE + E + P LA VE
Sbjct: 209 NTLPELQSLDEFGQSTDNPQ------------------------------LAH----VEA 234
Query: 330 TCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQN 389
C+ WFT E L+RF + P K F + +N ID++AI PY++T+ L E ++
Sbjct: 235 VCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIF--LTESN-------KS 285
Query: 390 GQQAMSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILF 448
Q ++ ++++ R++R+ RI KL+RHS GLQ LG TL+ S ELGLLI FL +G+++F
Sbjct: 286 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 345
Query: 449 SSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTI 508
SS V+FAE D T F SIP +FWWA +TMTTVGYGD+ P T+ GKIVG LC IAGVL I
Sbjct: 346 SSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVI 405
Query: 509 ALPVPVIVSNFNYFYHRETDHEEPAVLKEE 538
ALP+P+IV+NF+ FY +E +E A+ + E
Sbjct: 406 ALPIPIIVNNFSEFY-KEQKRQEKAIKRRE 434
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 246 bits (627), Expect = 6e-65
Identities = 177/490 (36%), Positives = 242/490 (49%), Gaps = 111/490 (22%)
Query: 108 EDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRN------ 161
E+ A G AS +++ IN+ G R ET TL P T L A P +
Sbjct: 27 EEMAKGEAS---EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGS 83
Query: 162 ---------EYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQL------- 205
E+FFDR+ F +L YY++G +L P +V +F +E+ F+ +
Sbjct: 84 SGSSGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEP 142
Query: 206 -----------GDEAMERFRE-----------DEGFIKEEEKPLPR-------------- 229
+EA++ F DE E E L R
Sbjct: 143 CCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGS 202
Query: 230 ---NEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDER---ELLR 283
+Q ++W +FE P SS +AR +A S+ IL+SI TFCLET F +R E+LR
Sbjct: 203 GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR 262
Query: 284 HPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRF 343
N + V T P+L +E CV+WFT E LVR
Sbjct: 263 V-------------GNITSVHFRREVET-EPILT--------YIEGVCVLWFTLEFLVRI 300
Query: 344 FACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVI 402
CP F +N++NIID VAI P+++ +G G + + A L LRV+
Sbjct: 301 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLS-----------GLSSKAARDVLGFLRVV 349
Query: 403 RLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEA----- 457
R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +GV++F++ +Y+AE
Sbjct: 350 RFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARP 409
Query: 458 ----DNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVP 513
N T F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVP
Sbjct: 410 SDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVP 469
Query: 514 VIVSNFNYFY 523
VIV+NF +Y
Sbjct: 470 VIVNNFGMYY 479
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 246 bits (627), Expect = 6e-65
Identities = 177/490 (36%), Positives = 242/490 (49%), Gaps = 111/490 (22%)
Query: 108 EDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRN------ 161
E+ A G AS +++ IN+ G R ET TL P T L A P +
Sbjct: 27 EEMAKGEAS---EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGS 83
Query: 162 ---------EYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQL------- 205
E+FFDR+ F +L YY++G +L P +V +F +E+ F+ +
Sbjct: 84 SGSSGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEP 142
Query: 206 -----------GDEAMERFRE-----------DEGFIKEEEKPLPR-------------- 229
+EA++ F DE E E L R
Sbjct: 143 CCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGS 202
Query: 230 ---NEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDER---ELLR 283
+Q ++W +FE P SS +AR +A S+ IL+SI TFCLET F +R E+LR
Sbjct: 203 GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR 262
Query: 284 HPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRF 343
N + V T P+L +E CV+WFT E LVR
Sbjct: 263 V-------------GNITSVHFRREVET-EPILT--------YIEGVCVLWFTLEFLVRI 300
Query: 344 FACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVI 402
CP F +N++NIID VAI P+++ +G G + + A L LRV+
Sbjct: 301 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLS-----------GLSSKAARDVLGFLRVV 349
Query: 403 RLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEA----- 457
R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +GV++F++ +Y+AE
Sbjct: 350 RFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARP 409
Query: 458 ----DNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVP 513
N T F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVP
Sbjct: 410 SDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVP 469
Query: 514 VIVSNFNYFY 523
VIV+NF +Y
Sbjct: 470 VIVNNFGMYY 479
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 246 bits (627), Expect = 6e-65
Identities = 177/490 (36%), Positives = 242/490 (49%), Gaps = 111/490 (22%)
Query: 108 EDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRN------ 161
E+ A G AS +++ IN+ G R ET TL P T L A P +
Sbjct: 27 EEMAKGEAS---EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGS 83
Query: 162 ---------EYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQL------- 205
E+FFDR+ F +L YY++G +L P +V +F +E+ F+ +
Sbjct: 84 SGSSGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEP 142
Query: 206 -----------GDEAMERFRE-----------DEGFIKEEEKPLPR-------------- 229
+EA++ F DE E E L R
Sbjct: 143 CCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGS 202
Query: 230 ---NEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDER---ELLR 283
+Q ++W +FE P SS +AR +A S+ IL+SI TFCLET F +R E+LR
Sbjct: 203 GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR 262
Query: 284 HPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRF 343
N + V T P+L +E CV+WFT E LVR
Sbjct: 263 V-------------GNITSVHFRREVET-EPILT--------YIEGVCVLWFTLEFLVRI 300
Query: 344 FACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVI 402
CP F +N++NIID VAI P+++ +G G + + A L LRV+
Sbjct: 301 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLS-----------GLSSKAARDVLGFLRVV 349
Query: 403 RLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEA----- 457
R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +GV++F++ +Y+AE
Sbjct: 350 RFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARP 409
Query: 458 ----DNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVP 513
N T F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVP
Sbjct: 410 SDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVP 469
Query: 514 VIVSNFNYFY 523
VIV+NF +Y
Sbjct: 470 VIVNNFGMYY 479
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 238 bits (607), Expect = 1e-62
Identities = 156/413 (37%), Positives = 217/413 (52%), Gaps = 84/413 (20%)
Query: 162 EYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQL---------------- 205
E+FFDR+ F +L YY++G +L P +V +F +E+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 206 --GDEAMERFR----------EDE-------------GFIKEEEKPLPRNEFQRQVWLIF 240
+EA++ F +DE G + K Q ++W +F
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 241 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG 300
E P SS +AR IA S+ IL+SI TFCLET F + P NG
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTE------------PVING 267
Query: 301 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII 360
+ V+ T L VE CV+WFTFE LVR P+K F +N++NII
Sbjct: 268 TSVVLQYEIETDPALT---------YVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNII 318
Query: 361 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVIRLVRVFRIFKLSRHSKG 419
D VAI P+++ +G G + + A L LRV+R VR+ RIFKL+RH G
Sbjct: 319 DFVAILPFYLEVGLS-----------GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVG 367
Query: 420 LQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE---------ADNQGTHFSSIPDA 470
L++LG TL+AS E LLI FL +GV++F++ +Y+AE + ++ T F +IP
Sbjct: 368 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIG 427
Query: 471 FWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 523
FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 428 FWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 238 bits (607), Expect = 1e-62
Identities = 156/413 (37%), Positives = 217/413 (52%), Gaps = 84/413 (20%)
Query: 162 EYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQL---------------- 205
E+FFDR+ F +L YY++G +L P +V +F +E+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 206 --GDEAMERFR----------EDE-------------GFIKEEEKPLPRNEFQRQVWLIF 240
+EA++ F +DE G + K Q ++W +F
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 241 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG 300
E P SS +AR IA S+ IL+SI TFCLET F + P NG
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTE------------PVING 267
Query: 301 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII 360
+ V+ T L VE CV+WFTFE LVR P+K F +N++NII
Sbjct: 268 TSVVLQYEIETDPALT---------YVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNII 318
Query: 361 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVIRLVRVFRIFKLSRHSKG 419
D VAI P+++ +G G + + A L LRV+R VR+ RIFKL+RH G
Sbjct: 319 DFVAILPFYLEVGLS-----------GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVG 367
Query: 420 LQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE---------ADNQGTHFSSIPDA 470
L++LG TL+AS E LLI FL +GV++F++ +Y+AE + ++ T F +IP
Sbjct: 368 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIG 427
Query: 471 FWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 523
FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 428 FWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 238 bits (607), Expect = 1e-62
Identities = 156/413 (37%), Positives = 217/413 (52%), Gaps = 84/413 (20%)
Query: 162 EYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQL---------------- 205
E+FFDR+ F +L YY++G +L P +V +F +E+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 206 --GDEAMERFR----------EDE-------------GFIKEEEKPLPRNEFQRQVWLIF 240
+EA++ F +DE G + K Q ++W +F
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 241 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG 300
E P SS +AR IA S+ IL+SI TFCLET F + P NG
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTE------------PVING 267
Query: 301 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII 360
+ V+ T L VE CV+WFTFE LVR P+K F +N++NII
Sbjct: 268 TSVVLQYEIETDPALT---------YVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNII 318
Query: 361 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVIRLVRVFRIFKLSRHSKG 419
D VAI P+++ +G G + + A L LRV+R VR+ RIFKL+RH G
Sbjct: 319 DFVAILPFYLEVGLS-----------GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVG 367
Query: 420 LQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE---------ADNQGTHFSSIPDA 470
L++LG TL+AS E LLI FL +GV++F++ +Y+AE + ++ T F +IP
Sbjct: 368 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIG 427
Query: 471 FWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 523
FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 428 FWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 233 bits (593), Expect = 5e-61
Identities = 138/303 (45%), Positives = 182/303 (60%), Gaps = 39/303 (12%)
Query: 232 FQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQP 291
+Q +VW +FE P SS +AR +A S+ ILISI TFCLET F +
Sbjct: 272 WQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGF------IHISNKTVTQ 325
Query: 292 PAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFI-VETTCVIWFTFELLVRFFACPSKA 350
+P PGA PP T + +PF VE CV+WFTFE L+R CP K
Sbjct: 326 ASPIPGA-------PPENITNVEVE----TEPFLTYVEGVCVVWFTFEFLMRITFCPDKV 374
Query: 351 GFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMS-LAILRVIRLVRVFR 409
F ++ +NIID VAI P+++ +G G + + A L LRV+R VR+ R
Sbjct: 375 EFLKSSLNIIDCVAILPFYLEVGLS-----------GLSSKAAKDVLGFLRVVRFVRILR 423
Query: 410 IFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE---AD------NQ 460
IFKL+RH GL++LG TL+AS E LLI FL +GV++F++ +Y+AE AD +
Sbjct: 424 IFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSN 483
Query: 461 GTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFN 520
T+F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF
Sbjct: 484 HTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFG 543
Query: 521 YFY 523
+Y
Sbjct: 544 MYY 546
Score = 72.8 bits (177), Expect = 9e-13
Identities = 52/171 (30%), Positives = 78/171 (45%), Gaps = 18/171 (10%)
Query: 58 RDADSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPE-------------DEEEEGDPGL 104
R S +P PP P P PPLP + +P +P P D E PGL
Sbjct: 13 RQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGL 72
Query: 105 GTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLG---DPAKRLRY-FDPLR 160
G ++ IN+ G+R ET TL P T L +P R+ +DP
Sbjct: 73 PAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGA 132
Query: 161 NEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAME 211
+E+FFDR+ F +L YY++ G+L P +V +F +E+ F+ + + +E
Sbjct: 133 DEFFFDRHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEELGFWGIDETDVE 182
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 222 bits (565), Expect = 9e-58
Identities = 143/448 (31%), Positives = 233/448 (52%), Gaps = 71/448 (15%)
Query: 120 QRVHINISGLRFETQLGTLAQFPNTLLG--------DPAKRL-RYFDPLRNEYFFDRNRP 170
+ + +N+ G+R + LA+FP T LG + A+RL +D E++FDR+
Sbjct: 50 EALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPG 109
Query: 171 SFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAME-----RFRE---------D 216
F +L++Y++G L + + F E ++ LG+ A+ R+ E D
Sbjct: 110 FFLSLLHFYRTG-HLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWD 168
Query: 217 EGF------------IKEEEKPLPR------NEFQRQVWLIFEYPESSGSARAIAIVSVL 258
E I + ++ L R +R++WL E P S ++ + VS+
Sbjct: 169 EDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIS 228
Query: 259 VILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPR 318
V+L SI C+ +LPE++ A A A +G P G P+L R
Sbjct: 229 VVLASIAAMCIHSLPEYQAREA------------AAAVAAVAAG--RSPEGVRDDPVLRR 274
Query: 319 TLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAE 378
+E C+ WF+FE+ R PS F + +N+ID+V++ P+++TL +A
Sbjct: 275 --------LEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVAL 326
Query: 379 QQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLI 438
GG G G+ +++V RL+R+FR+ KL+RHS GL+ LG TL+ S RE+G+L+
Sbjct: 327 GDQGGKEFGHLGK------VVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILL 380
Query: 439 FFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGS 498
+L +GV +FS Y AE + + F++IP +WW V+MTTVGYGD+ P+TV GK+ S
Sbjct: 381 LYLAVGVSVFSGVAYTAEKE-EDVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAAS 439
Query: 499 LCAIAGVLTIALPVPVIVSNFNYFYHRE 526
C + G+L +ALP+ +I + F++FY R+
Sbjct: 440 GCILGGILVVALPITIIFNKFSHFYRRQ 467
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 219 bits (557), Expect = 8e-57
Identities = 146/459 (31%), Positives = 230/459 (50%), Gaps = 89/459 (19%)
Query: 115 ASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPA---------KRLRYFDPLRNEYFF 165
A++ + IN+ G + + TL +FP T LG + +D ++ E++F
Sbjct: 12 ANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYF 71
Query: 166 DRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLG------------------- 206
DRN F +L++Y +G +L + + F+ EI ++ +
Sbjct: 72 DRNPELFPYVLHFYHTG-KLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEP 130
Query: 207 -----DEAMER------FREDEGFIKEEEK--PLPRNEFQRQVWLIFEYPESSGSARAIA 253
DE ++ F E F + K P F+RQ+WL + P S +R +
Sbjct: 131 EQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFS 190
Query: 254 IVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVA 313
I+S+LV++ SIIT CL +LP+F+ P + G+ P P
Sbjct: 191 ILSILVVMGSIITMCLNSLPDFQ------------------IPDSQGN----PGEDPR-- 226
Query: 314 PLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLG 373
F IVE + WFTFEL+ RF P F +N +N+ID+++I P++ITL
Sbjct: 227 ----------FEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLV 276
Query: 374 TELA-EQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMR 432
L E P G+ + +V+RL+R+FRI KL+RHS GL+ LG TL+ S +
Sbjct: 277 VNLVVESTPTLANLGR---------VAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYK 327
Query: 433 ELGLLIFFLFIGVILFSSAVYFAEAD-NQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITV 491
E+GLL+ +L +G+ +FS Y E + N+G ++IP +WWA V+MTTVGYGD+ P T
Sbjct: 328 EVGLLLLYLSVGISIFSVVAYTIEKEENEG--LATIPACWWWATVSMTTVGYGDVVPGTT 385
Query: 492 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHE 530
GK+ S C +AG+L + LP+ +I + F++FY R+ E
Sbjct: 386 AGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLE 424
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 218 bits (554), Expect = 2e-56
Identities = 138/449 (30%), Positives = 221/449 (49%), Gaps = 89/449 (19%)
Query: 122 VHINISGLRFETQLGTLAQFPNTLLG------DPAKRLRYFDPLR---NEYFFDRNRPSF 172
V++N+ G + TL +FP+T LG L D EY+FDRN F
Sbjct: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
Query: 173 DGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMER-------------------- 212
+L +Y +G +L + + F EI ++ + + ++
Sbjct: 77 RYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQ 135
Query: 213 ----------FREDEGFIKEEEK--PLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVI 260
F E F KE EK L + ++++W+ E P SA+ IAI S+ V+
Sbjct: 136 KSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVV 195
Query: 261 LISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTL 320
L SI+ C+ ++ EF++E G P+L
Sbjct: 196 LASIVAMCVHSMSEFQNE-----------------------------DGEVDDPVLEG-- 224
Query: 321 ADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQ 380
VE C+ WFT EL VR A P + F +N +NIID V+I P++ TL + E++
Sbjct: 225 ------VEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEE 278
Query: 381 PGGGGGGQNGQQAMSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIF 439
+ ++ +++++RL+R+FRI KL+RHS GL+ LG TL+ S E+GLL+
Sbjct: 279 ---------SEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLL 329
Query: 440 FLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSL 499
FL +G+ +FS +Y E D+ + +SIP +WWA ++MTTVGYGD P+T+ GK++ S
Sbjct: 330 FLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIAST 389
Query: 500 CAIAGVLTIALPVPVIVSNFNYFYHRETD 528
C I G+L +ALP+ +I + F+ +Y ++ D
Sbjct: 390 CIICGILVVALPITIIFNKFSKYYQKQKD 418
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 209 bits (531), Expect = 8e-54
Identities = 140/440 (31%), Positives = 225/440 (51%), Gaps = 87/440 (19%)
Query: 124 INISGLRFETQLGTLAQFPNTLLGDPAKRLRY-----------FDPLRNEYFFDRNRPSF 172
+N+ G+R L+Q+P T L + L +DP + E++FDR+ +F
Sbjct: 27 VNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAF 86
Query: 173 DGIL--YYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEE-KPLPR 229
++ YY+ G + + F +E+ F+++ + ++ + K EE + + R
Sbjct: 87 KCVIEVYYF---GEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIAR 143
Query: 230 N------------------EFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLET 271
Q+ VW E PESS AR +A++S L+IL+S + C+ T
Sbjct: 144 RVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGT 203
Query: 272 LPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTC 331
+PE + A G+ V P TL + VET C
Sbjct: 204 IPELQ------------------VLDAEGNRVEHP------------TLEN----VETAC 229
Query: 332 VIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITL-----GTELAEQQPGGGGG 386
+ WFT E L+R F+ P+K F+ + MNI+DV+AI P++++L G + E
Sbjct: 230 IGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELT------ 283
Query: 387 GQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVI 446
N QQA+ + +R++R+ RIFKL+RHS GLQ L L+ S +ELGLL+ +L +G+
Sbjct: 284 --NVQQAV-----QALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIF 336
Query: 447 LFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVL 506
+FS+ Y E + T F SIP +FWWA++TMTTVGYGD+ P T GK+ ++ + GV+
Sbjct: 337 VFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVI 396
Query: 507 TIALPVPVIVSNFNYFYHRE 526
IALP+ I++NF +Y+++
Sbjct: 397 AIALPIHPIINNFVRYYNKQ 416
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 206 bits (523), Expect = 7e-53
Identities = 136/443 (30%), Positives = 213/443 (48%), Gaps = 93/443 (20%)
Query: 124 INISGLRFETQLGTLAQFPNTLLG-------------------DPAKRLRYFDPLRNEYF 164
+N+ G RF L+ FP+T LG P + +P+ NEYF
Sbjct: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
Query: 165 FDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEE- 223
FDR+ +F +L+YY++G RL + F EI+++ + + +++ D F ++E
Sbjct: 103 FDRSSQAFRYVLHYYRTG-RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKEL 161
Query: 224 ------EKPLPRNEFQRQ----------------VWLIFEYPESSGSARAIAIVSVLVIL 261
+K E Q + +W I E P SS +AR ++S++ ++
Sbjct: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVV 221
Query: 262 ISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLA 321
+SII L + + +LL
Sbjct: 222 VSIINMALMSAELSWLDLQLLE-------------------------------------- 243
Query: 322 DPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQP 381
I+E C+ WFT E ++RF + F R + NIID++AI P++ITL E
Sbjct: 244 ----ILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLS--- 296
Query: 382 GGGGGGQNGQQAMSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFF 440
G Q Q+ ++ I++V+RL+R R+ KL RHS GL+ LG T+ E+GLL+ F
Sbjct: 297 ----GSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLF 352
Query: 441 LFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLC 500
L +G+ +FS+ YFAE T F+S+P A+WWA +MTTVGYGD+RP T GKIV +C
Sbjct: 353 LSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMC 412
Query: 501 AIAGVLTIALPVPVIVSNFNYFY 523
++G+L +ALP+ +I F+ Y
Sbjct: 413 ILSGILVLALPIAIINDRFSACY 435
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 201 bits (510), Expect = 2e-51
Identities = 137/439 (31%), Positives = 219/439 (49%), Gaps = 68/439 (15%)
Query: 122 VHINISGLRFETQLGTLAQFP----NTLLGDPAKR-----LRYFDPLRNEYFFDRNRPSF 172
V +N+ G R+ L FP + L G ++R +D RNEYFFDR+ +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 173 DGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMER----------------FRED 216
IL Y + G+LR + F +E+ ++ L +E + D
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 217 EGFI--KEEEKPLPRNEFQRQVWL-----IFEYPESSGSARAIAIVSVLVILISIITFCL 269
E + ++E +P + WL FE P SS +A+ +A VSV+ +++S++ C
Sbjct: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
Query: 270 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVET 329
TLP++R+ A A + +GP +P I+E
Sbjct: 191 STLPDWRN---------------AAADNRSLDDRSRYSAGPG---------REPSGIIEA 226
Query: 330 TCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQN 389
C+ WFT E +VRF +K F + +NIID++AI PY+I++ + G+N
Sbjct: 227 ICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFT--------GEN 278
Query: 390 GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFS 449
Q + LRV+R++R+F + KL+RH GLQ LG TL+ RE+ +L+ F+ + + +FS
Sbjct: 279 SQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFS 338
Query: 450 SAVYFAE----ADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGV 505
+ E + F+SIP A WW +++MTTVGYGDM PITV G+I+G +C ++G+
Sbjct: 339 ALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGI 398
Query: 506 LTIALPVPVIVSNFNYFYH 524
+ +ALP+ I +F YH
Sbjct: 399 VLLALPITFIYHSFVQCYH 417
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 199 bits (506), Expect = 6e-51
Identities = 136/439 (30%), Positives = 216/439 (49%), Gaps = 79/439 (17%)
Query: 122 VHINISGLRFETQLGTLAQFP----NTLLGDPAKR-----LRYFDPLRNEYFFDRNRPSF 172
V +N+ G R+ L FP + L G ++R +D RNEYFFDR+ +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 173 DGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMER----------------FRED 216
IL Y + G+LR + F +E+ ++ L +E + D
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 217 EGFI--KEEEKPLPRNEFQRQVWL-----IFEYPESSGSARAIAIVSVLVILISIITFCL 269
E + ++E +P + WL FE P SS +A+ +A VSV+ +++S++ C
Sbjct: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
Query: 270 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVET 329
TLP++R+ A R+L D I+E
Sbjct: 191 STLPDWRN-----------------------------------AAADNRSLDDRSRIIEA 215
Query: 330 TCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQN 389
C+ WFT E +VRF +K F + +NIID++AI PY+I++ + G+N
Sbjct: 216 ICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFT--------GEN 267
Query: 390 GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFS 449
Q + LRV+R++R+F + KL+RH GLQ LG TL+ RE+ +L+ F+ + + +FS
Sbjct: 268 SQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFS 327
Query: 450 SAVYFAE----ADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGV 505
+ E + F+SIP A WW +++MTTVGYGDM PITV G+I+G +C ++G+
Sbjct: 328 ALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGI 387
Query: 506 LTIALPVPVIVSNFNYFYH 524
+ +ALP+ I +F YH
Sbjct: 388 VLLALPITFIYHSFVQCYH 406
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,730,505
Number of Sequences: 37866
Number of extensions: 1638682
Number of successful extensions: 18593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 296
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 13566
Number of HSP's gapped (non-prelim): 4437
length of query: 613
length of database: 18,247,518
effective HSP length: 108
effective length of query: 505
effective length of database: 14,157,990
effective search space: 7149784950
effective search space used: 7149784950
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.