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Search of human proteins with 253970412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens]
(739 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens] 1465 0.0
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 66 1e-10
gi|91982772 mucin 17 [Homo sapiens] 61 3e-09
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 59 2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 2e-08
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 58 3e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 58 3e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 57 8e-08
gi|112421108 capicua homolog [Homo sapiens] 57 8e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 57 8e-08
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 55 2e-07
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 55 2e-07
gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo sa... 55 3e-07
gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo sa... 55 3e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 55 3e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 54 4e-07
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 54 7e-07
gi|112363080 microtubule associated serine/threonine kinase 2 [H... 53 1e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 52 2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 52 2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 2e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens] 50 8e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 50 8e-06
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 50 8e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 50 1e-05
gi|197276670 spermatogenesis and centriole associated 1 isoform ... 49 1e-05
gi|197276668 spermatogenesis and centriole associated 1 isoform ... 49 1e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 49 2e-05
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 49 2e-05
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 49 2e-05
>gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens]
Length = 739
Score = 1465 bits (3792), Expect = 0.0
Identities = 739/739 (100%), Positives = 739/739 (100%)
Query: 1 MEGGGGRDEPSACRAGDVNMDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGH 60
MEGGGGRDEPSACRAGDVNMDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGH
Sbjct: 1 MEGGGGRDEPSACRAGDVNMDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGH 60
Query: 61 KERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQA 120
KERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQA
Sbjct: 61 KERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQA 120
Query: 121 AQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGE 180
AQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGE
Sbjct: 121 AQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGE 180
Query: 181 PRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRA 240
PRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRA
Sbjct: 181 PRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRA 240
Query: 241 ASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQG 300
ASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQG
Sbjct: 241 ASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQG 300
Query: 301 KRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIP 360
KRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIP
Sbjct: 301 KRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIP 360
Query: 361 ANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQ 420
ANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQ
Sbjct: 361 ANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQ 420
Query: 421 PQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDS 480
PQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDS
Sbjct: 421 PQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDS 480
Query: 481 PDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSG 540
PDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSG
Sbjct: 481 PDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSG 540
Query: 541 LPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSP 600
LPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSP
Sbjct: 541 LPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSP 600
Query: 601 PSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAA 660
PSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAA
Sbjct: 601 PSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAA 660
Query: 661 SQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPL 720
SQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPL
Sbjct: 661 SQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPL 720
Query: 721 IQLSPEADKENVDSPLLKF 739
IQLSPEADKENVDSPLLKF
Sbjct: 721 IQLSPEADKENVDSPLLKF 739
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 65.9 bits (159), Expect = 1e-10
Identities = 109/486 (22%), Positives = 181/486 (37%), Gaps = 49/486 (10%)
Query: 188 PALPSSGAQARLTRAPGPPHSAHALPRESC-TAHAASQAATQRKPGTKLLLPRAASVRGR 246
P++ ++G AR+++ P P +P S TA AA+ A+ R P AS R
Sbjct: 2197 PSMSAAGLAARMSQVPAP------VPLMSLRTAPAANLAS--RIPAASAAAMNLASARTP 2248
Query: 247 SIPGAAEKPKKEIPASPS-------RTKIPAEKESHRDVLPDKPAPGAVNV-----PAAG 294
+IP A PA+ + RT + + D P P AVN+ PAA
Sbjct: 2249 AIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLAD--PRTPTAPAVNLAGARTPAAL 2306
Query: 295 SHLG-QGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKS 353
+ L G P +AP S + + +S+ + + T+ A+ A
Sbjct: 2307 AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASL 2366
Query: 354 SEFASIPANSSR-------PLSNISK-SGRMGPAMLRPALPAGPVGASSWQAKRVDVSEL 405
+ PA S PLS + SGR P +L A P A S + +
Sbjct: 2367 TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
Query: 406 AAEQLTAPPSAS-----PTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKT 460
+ ++ PS S QP++P S C ++++ + ++S+ + + T
Sbjct: 2427 PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL--SSGAVATTT 2484
Query: 461 KVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSV--GRVTVHSTPVRRSSGPAP 518
+P + S P + AQ+P + ++ + S+ SS +
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 519 QSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARR-RSSEPRKNSAMRTE 577
S S+ S+ + +S P+ P+ + V SP P R P E
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP-------PE 2597
Query: 578 PTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGD 637
PT ++ S S S S + + S S S+ S S+++ + AKPG
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
Query: 638 AAPSEA 643
A P A
Sbjct: 2658 ALPKPA 2663
Score = 56.2 bits (134), Expect = 1e-07
Identities = 110/501 (21%), Positives = 173/501 (34%), Gaps = 51/501 (10%)
Query: 153 EMKKSPTSLKRETYYLSDSPLLGPPVG------EPRLLASSPALPSSGA-QARLTRAPGP 205
E+ + R + +SDS + G E + A P P S ++ +R+P P
Sbjct: 126 ELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTP 185
Query: 206 PHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRS-----IPGAAEKPK-KEI 259
++ +S +RK +K R+ S + P + K K K+
Sbjct: 186 KQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR 245
Query: 260 PASPSRTKIPAEKESHRDVLPDKPAPGAVN-----VPAAGSHLGQ--GKRAIPVPNKLGL 312
S S T P + +HR D + + AA +H G+ P + G
Sbjct: 246 KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
Query: 313 KKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISK 372
PG+TS + S P A+ +SP K K + S A P S
Sbjct: 306 GDAPFSEPGTTST---QRPSSP--ETATKQPSSPYEDKDKDKKEKS--ATRPSPSPERSS 358
Query: 373 SGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLN 432
+G PA P L G+ A + L+ E + P ASPT+ ++P + L
Sbjct: 359 TGPEPPAPT-PLLAERHGGSPQPLA----TTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
Query: 433 SSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQ 492
S + S + + R S K P P + + I SP S RA+
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE-----ISSSPTSKNRSHGRAK 468
Query: 493 RPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRA 552
R +S + H+ R +P + R S PT S P +
Sbjct: 469 RDKSHS-------HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR 521
Query: 553 VGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSP 612
G R RS P++ R+ T+ R +R RG SR P S
Sbjct: 522 WGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR-------RGRSHSRSPATRGRSR 574
Query: 613 EESDSTFSKSTATEVAREEAK 633
+ + +S + AR ++
Sbjct: 575 SRTPARRGRSRSRTPARRRSR 595
Score = 55.5 bits (132), Expect = 2e-07
Identities = 103/437 (23%), Positives = 158/437 (36%), Gaps = 84/437 (19%)
Query: 211 ALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRS--IPG--------------AAEK 254
A+PR ++S ++ + K G LPR S R RS PG +
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDG----LPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSP 1464
Query: 255 PKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKK 314
K+IP +PSR + + LP P P + + S K P + G +
Sbjct: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS---RSPSSPELNNKCLTPQRERSGSES 1521
Query: 315 TLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIP---ANSSRPLSNIS 371
++ + + + L ++S SG + P+ + SE S P A + PL S
Sbjct: 1522 SVDQKTVARTPLGQRSRSG----SSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS 1577
Query: 372 KSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWL 431
+SG + L P + S + V AA + + +SP +P+ P
Sbjct: 1578 RSGSSPEVDSKSRL--SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSP-EPKAP------- 1627
Query: 432 NSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRA 491
R++ RR +S P+P S +S PK A
Sbjct: 1628 -------------APRALPRRSRSGSSSKGRGPSPEGS------SSTESSPEHPPKSRTA 1668
Query: 492 QRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPR 551
+R + + + P RRSS +P+ AR + SR S P +T PR
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL-----SRRSRSASSSPETRSRTPPR 1723
Query: 552 -----AVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQ 606
+V SP PA + S R+ SA KT SR RG PS P+
Sbjct: 1724 HRRSPSVSSP--EPAEKSRSSRRRRSA------SSPRTKTTSR-------RGRSPSPKPR 1768
Query: 607 ALNFSPEESDSTFSKST 623
L S S +++T
Sbjct: 1769 GLQRSRSRSRREKTRTT 1785
Score = 52.8 bits (125), Expect = 1e-06
Identities = 113/477 (23%), Positives = 171/477 (35%), Gaps = 102/477 (21%)
Query: 186 SSPALPSSGAQARLTRAPGPPHSAHALP-------RESCTAHAASQAATQRKP---GTKL 235
SS P + A A L P SAHA R + AS + + P G L
Sbjct: 2325 SSSRTPQAPASANLVG----PRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANL 2380
Query: 236 LLPRAA-----SVRGRSIPGAAEKPKKEIPAS-PSRTKIPAEKESHRDVLPDKPAPGAVN 289
PR V GR+ P ++ + P S PS++++ +E+ P+P +
Sbjct: 2381 TSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERA---------PSPSSRM 2431
Query: 290 VPAAGSHL---GQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSP 346
A L Q + PVP+ + L A + ++ SSG V + SSA
Sbjct: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA---- 2487
Query: 347 AVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELA 406
+ S+PA P +P VG S LA
Sbjct: 2488 ----GDHNGMLSVPA---------------------PGVPHSDVGEPPASTGAQQPSALA 2522
Query: 407 AEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKV---- 462
A Q P+ + +SS + S SS + + S S L + +V
Sbjct: 2523 ALQ----PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Query: 463 MPTPTNQFKIPKFSIGDS-PDSSTP----KLSRAQRPQSCTSVGRVTVHSTPVRRSSGPA 517
+P+PT PK ++ + P TP + S + S +S + S+ SS +
Sbjct: 2579 VPSPT---PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 518 PQSLLSARRVSALPTPASRRCSGLP-PMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRT 576
S S+ S+ P+PA LP P +PK P P RRS PRK
Sbjct: 2636 SSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP---------PGERRSRSPRK------ 2680
Query: 577 EPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAK 633
+ DSR + SP PS P SP + S+ S+ + R +++
Sbjct: 2681 ----PIDSLRDSRSLSYSPVERRRPSPQP-----SPRDQQSSSSERGSRRGQRGDSR 2728
Score = 45.1 bits (105), Expect = 2e-04
Identities = 101/476 (21%), Positives = 169/476 (35%), Gaps = 64/476 (13%)
Query: 63 RCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRN-QAA 121
R A +N P P P A +P A A + SSSR QA
Sbjct: 2274 RTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAP 2333
Query: 122 QAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEP 181
+A PRS + +N+ +P SL S + P +
Sbjct: 2334 ASANLVGPRSA-------HATAPVNIAGSRTAAALAPASLT--------SARMAPALSGA 2378
Query: 182 RLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAA 241
L +SP +P S A R++ PP A R +A + S+ ++R P + +A
Sbjct: 2379 NL--TSPRVPLS-AYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP 2435
Query: 242 SVRGRSIPGAAEKPKKEIPASPS---------RTKIPAEKESHRDVLPDKPAP-----GA 287
S +P A ++P+ +P++ S T + + + + G
Sbjct: 2436 SQS--LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGM 2493
Query: 288 VNVPAAG---SHLGQ--GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSA 342
++VPA G S +G+ P+ L + + S+S+ + SSS S +SS+
Sbjct: 2494 LSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS--SSSSSS 2551
Query: 343 CTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDV 402
+S + + SE +S+P L + +R P P AKR
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT-----PAKRKRR 2606
Query: 403 SELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKV 462
S ++ ++ S+S +SS + S SS + + S S +S +
Sbjct: 2607 SSSSSSSSSSSSSSS--------------SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 463 MPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAP 518
P P +PK + P + ++P R +S RR P P
Sbjct: 2653 KPGPQ---ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705
Score = 42.7 bits (99), Expect = 0.001
Identities = 145/646 (22%), Positives = 240/646 (37%), Gaps = 104/646 (16%)
Query: 157 SPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRES 216
+PT L E + S PL P L+ P P S +A TR PP S LP+ S
Sbjct: 365 APTPLLAERHGGSPQPLATTP------LSQEPVNPPS--EASPTRDRSPPKSPEKLPQSS 416
Query: 217 CTA-------------HAASQAATQRK---PGTKLLLPRAASVRGRSIPGAAEKPKKEI- 259
+ HA+S + + PG+ + + + + RS G A++ K
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS-HGRAKRDKSHSH 475
Query: 260 -----------PASP----SRTKIPAEKESHRDVLPD-KPAPGAVNVPAAGSHLGQGKRA 303
PA+ SR++ P ++ R P + + A + S +G+
Sbjct: 476 TPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSR 535
Query: 304 IPV-PNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPAN 362
P P + T + ++ R S P G S + T G+++S A +
Sbjct: 536 SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSR 595
Query: 363 SSRPLSNISKS---GRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASP- 418
S P S+S R G + R PA + +R S A + S +P
Sbjct: 596 SRTPTRRRSRSRTPARRGRS--RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPA 653
Query: 419 ----TQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPK 474
++ +TP G+ + + A ++T + R R S+T ++ + +
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS---RSRTPRRGRSRSRSLVRR 710
Query: 475 FSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRS-SGPAPQ---SLLSARRVSAL 530
S TP+ +R +S +S R T RRS S +P+ S +S+RR +L
Sbjct: 711 ----GRSHSRTPQ----RRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762
Query: 531 PTPASRRCSGL------------PPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEP 578
+P S+ S L P +T PR S P + + PR++ + + P
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP 822
Query: 579 TRESNRKTDSRLVDVSPD------RGSPPSR----VPQALNFS-PEESDSTFSKSTATEV 627
++ + KT SR S G+PP + PQA S + S F S E+
Sbjct: 823 PKQKS-KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPEL 881
Query: 628 AREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSES- 686
+ P + + P +P +S P P + +P GS S
Sbjct: 882 --KSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP---QPKVKAIISPRQRSHSGSSSP 936
Query: 687 RPLIDLMTNTPDMNKNVAKPSPVVGQLI------DLSSPLIQLSPE 726
P TP +++V+ S V +L+ SSP ++ PE
Sbjct: 937 SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE 982
Score = 38.9 bits (89), Expect = 0.017
Identities = 93/492 (18%), Positives = 161/492 (32%), Gaps = 48/492 (9%)
Query: 116 SRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLG 175
SR+ K P + R E K L + + SP + R SP +
Sbjct: 1672 SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731
Query: 176 PPVGEPRLLAS----SPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKP 231
P + +S S + P + +R R+P P L R + T+R+
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP--KPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 232 GTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVP 291
+ ++ S R + + ++ S ++ PA +ES R + G P
Sbjct: 1790 RSGS--SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRT--SSRRRRGRSRTP 1845
Query: 292 AAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKA 351
S R P P K ++ S + R S P+ S S + V +
Sbjct: 1846 PT-SRKRSRSRTSPAPWKRS------RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898
Query: 352 KSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLT 411
+S S+ SR R P R + P R + + T
Sbjct: 1899 RSRSRTSVTRRRSR--------SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRT 1950
Query: 412 APPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFK 471
P + ++ +TP + + S +S + + RS R +++ +P + +
Sbjct: 1951 PPVTRRRSRSRTPP-----VTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRR 2005
Query: 472 IPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALP 531
S ++P R R ++ ++ R + TP+ L R S P
Sbjct: 2006 --------SRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL----------LPRKRSRSRSP 2047
Query: 532 TPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLV 591
RR P T + SP + R S S T P ++ + + V
Sbjct: 2048 LAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPV 2107
Query: 592 DVSPDRGSPPSR 603
++ R S SR
Sbjct: 2108 ALNSSRMSCFSR 2119
Score = 38.1 bits (87), Expect = 0.030
Identities = 62/239 (25%), Positives = 87/239 (36%), Gaps = 39/239 (16%)
Query: 406 AAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPT 465
A Q P S SP+ P+ LN+ C L R +S ++ KT V T
Sbjct: 1488 ALPQTPRPRSRSPSSPE--------LNNKC-------LTPQRERSGSESSVDQKT-VART 1531
Query: 466 PTNQFKIPKFSIGDSPDSST-PKLSRAQRPQSCTSVGRVTVHSTPVRRSS--GPAPQ--- 519
P Q + G S + P S +R +S +S TP+R+ S G +P+
Sbjct: 1532 PLGQ----RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
Query: 520 -SLLSARR--------VSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRK 570
S LS RR V P A R SG P +P +P R RS K
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP----APRALPRRSRSGSSSK 1643
Query: 571 NSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAR 629
E + + + + RGS S P+ + +P S+ S T AR
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702
Score = 33.1 bits (74), Expect = 0.95
Identities = 56/246 (22%), Positives = 84/246 (34%), Gaps = 40/246 (16%)
Query: 458 SKTKVMPTPTNQFKIPKFSIGDSPDSSTP----KLSRAQRPQSCTSVGRVTVHSTPV--- 510
S + PTP + K K G +SS+P K S ++ S + H +P
Sbjct: 177 SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKS 236
Query: 511 -----------RRSSGPAPQSLLSARRVSA---LPTPASRRCSGLPPMTPKTMPRAVGSP 556
RS+ PAP+S + R SA + SR S T A SP
Sbjct: 237 KRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSP 296
Query: 557 LCVPARRRS-----SEPRKNSAMRTEPTRESNRKTDSRLVDVSPDR----GSPPSRVPQA 607
RR SEP S R + ++ S D D+ + PS P+
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER 356
Query: 608 LNFSPEESDSTFSKS----------TATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTP 657
+ PE T + T +++E P +A+P+ E L +
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSS 416
Query: 658 DAASQP 663
+ S P
Sbjct: 417 SSESSP 422
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 61.2 bits (147), Expect = 3e-09
Identities = 130/590 (22%), Positives = 221/590 (37%), Gaps = 80/590 (13%)
Query: 159 TSLKRETYYLSDSPLLGPPVGEPRLLASSPA-------LPSSGAQARLTRAPGPPHSAHA 211
TS+ T +PL PV L+A+S A + S+ T A PP +A
Sbjct: 971 TSIPTSTPSEGTTPLTSTPVSHT-LVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEG 1029
Query: 212 LPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAE 271
+ T S T+ T ++ A + +P+ T P
Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMV---------------ASSETSTLSTTPADTSTPVT 1074
Query: 272 KESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKK---TLLKAPGSTS---N 325
S A G + S ++PV +L + TL P TS
Sbjct: 1075 TYSQASS-SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVT 1133
Query: 326 LARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPAL 385
+ ++SS P + +S TSP P+ + PL+++ S + + L
Sbjct: 1134 TSTEASSSPTTAEGTSIPTSP-------------PSEGTTPLASMPVSTTLVVSSEANTL 1180
Query: 386 PAGPVGASSWQAKRVDVSELA-AEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLN 444
PV + + A + S ++T+ P+++P + TP ++ A SE+S L+
Sbjct: 1181 STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS 1240
Query: 445 KTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVT 504
+ +++T PT +P + + + ST S TS T
Sbjct: 1241 TSPVDTSTPVTTSAETSSSPTTAEGTSLPTST---TSEGSTLLTSIPVSTTLVTSPEAST 1297
Query: 505 VHSTPVRRSSGPAPQSLLSARRVSALPTPA-------SRRCSGLPPMT--PKTMPRAVGS 555
+ +TPV + GP ++++ VS+ PTPA S G P+T P S
Sbjct: 1298 LLTTPVD-TKGP----VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASS 1352
Query: 556 PLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSR---LVDVSPDRGSPP-SRVPQALNFS 611
+ + S+ P NS T T + T S + + +P G+ P + +P +
Sbjct: 1353 AISI----LSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPV 1408
Query: 612 PEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLID 671
ST S AT V + + PG +A EA E +++ S+ L I
Sbjct: 1409 VSSEASTLS---ATPV--DTSTPGTTSA--EATSSPTTAEGISIPTSTPSEGKTPLKSIP 1461
Query: 672 FCDTPEAHVAVGSESRPLIDLMTNTPDMNKNV--AKPSPVVGQLIDLSSP 719
+TP A+ + S +D +N+P + + P+P G I +S+P
Sbjct: 1462 VSNTPVANSEASTLSTTPVD--SNSPVVTSTAVSSSPTPAEGTSIAISTP 1509
Score = 58.9 bits (141), Expect = 2e-08
Identities = 138/650 (21%), Positives = 210/650 (32%), Gaps = 140/650 (21%)
Query: 171 SPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAH----AASQAA 226
S L PV + +S + SS A T P +S + P S A+S+A+
Sbjct: 2533 STLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAS 2592
Query: 227 TQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIP-------------------ASPSRTK 267
T +P S S P A+ I AS +
Sbjct: 2593 TLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST 2652
Query: 268 IPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQ---GKRAIPVPNKLGLKKTLLKAPGSTS 324
+ R ++ + A GS + G+R+ P+ N L L + ST
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTL 2712
Query: 325 NLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPA 384
+ +S PV + A A +SP + S S P++ S PL++I S
Sbjct: 2713 STTPVDTSTPVTTSAE-ASSSPTTAEGTSMRI-STPSDGSTPLTSILVS----------T 2760
Query: 385 LPAGPVGASSWQAKRVDVS-----------ELAAEQLTAPPSASPTQPQTPEGGGQWLNS 433
LP AS+ VD S ++T+ P+++P++ TP ++
Sbjct: 2761 LPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHT 2820
Query: 434 SCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDS-------PDSSTP 486
A SE+ L+ T ++K PT +P + + P S+TP
Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880
Query: 487 KLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAP--------------QSLLSARRVSALPT 532
S S T V +T SS P + L++ VS +P
Sbjct: 2881 VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV 2940
Query: 533 PASRRCS----GLPPMTPKTMPRAVGS----------PLCVPARRRSSEPRKNSAMRTEP 578
S + + TP T S P+ P RR+ P + ++ T P
Sbjct: 2941 AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT--PLTSMSVSTMP 2998
Query: 579 TRESNRKTDSRL-VDVS-------------------------PDRGSPPSR--------- 603
S T SR D S P GS P
Sbjct: 2999 VASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPV 3058
Query: 604 -VPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQ 662
+P+A S DS T+TEV+ G + P T S
Sbjct: 3059 AIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS-------------TYSEGST 3105
Query: 663 PLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQ 712
PL +P+ TP A+ + S +D T+TP A SP +
Sbjct: 3106 PLTGVPV---STTPVTSSAISTLSTTPVD--TSTPVTTSTEAHSSPTTSE 3150
Score = 54.3 bits (129), Expect = 4e-07
Identities = 115/542 (21%), Positives = 198/542 (36%), Gaps = 58/542 (10%)
Query: 153 EMKKSPT-----SLKRETYYLSDSPLLGPPVGEPRLLASSPA------LPSSGAQARLTR 201
E+ SPT S+ TY +PL G PV + +S+ + + +S T
Sbjct: 3082 EVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTE 3141
Query: 202 APGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPA 261
A P ++ + T S T T L++ S + + A
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA 3201
Query: 262 SPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPG 321
+ S T AE S P + +VP + + + + +I L T + +
Sbjct: 3202 TSSTT---AEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI-------LSTTPVDSNT 3251
Query: 322 STSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAML 381
+ SSS P G S ++P+ G S+ S+P +++ S+ + +
Sbjct: 3252 PLTTSTEASSSPPTAEGTSMPTSTPSEG---STPLTSMPVSTTTVASSETST-----LST 3303
Query: 382 RPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESS 441
PA + PV S + +++ T+ P+++ ++ TP + + SE+S
Sbjct: 3304 TPADTSTPVTTYSQASSSPPIADG-----TSMPTSTYSEGSTPLTNMSFSTTPVVSSEAS 3358
Query: 442 QLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFS-------IGDSPDSSTPKLSRAQRP 494
L+ T +++ + PT IP S + P S+TP +S
Sbjct: 3359 TLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT 3418
Query: 495 QSCTSVGRVTVHSTPVRRSSGP--APQSLLSARRVSALPTPASRRCSGLPPM------TP 546
S T V T+ +T SS P A + L S TP S P+ T
Sbjct: 3419 LSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTL 3478
Query: 547 KTMPRAVGSPLCVPARRRSSEPRKN-SAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVP 605
T P +P+ + SS ++M T E + + V +P S S
Sbjct: 3479 STTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAS--- 3535
Query: 606 QALNFSPEESDS--TFSKSTATEVAREEAKPGGDAAPSE--ALLVDIKLEPLAVTPDAAS 661
L+ +P +S++ T S ++ A + + PSE + L + L VT AS
Sbjct: 3536 -TLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAS 3594
Query: 662 QP 663
P
Sbjct: 3595 TP 3596
Score = 49.7 bits (117), Expect = 1e-05
Identities = 129/599 (21%), Positives = 210/599 (35%), Gaps = 116/599 (19%)
Query: 153 EMKKSPT-----SLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPH 207
E+ SPT S+ TY +PL PV + L +S A + L+ P
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPV--------NTTLVASSAISILSTTPVDNS 1365
Query: 208 SAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTK 267
+ E+C++ S+ GT + S P P IP S T
Sbjct: 1366 TPVTTSTEACSSPTTSE-------GTSM---------PNSNPSEGTTPLTSIPVST--TP 1407
Query: 268 IPAEKESHRDVLP-DKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNL 326
+ + + S P D PG + A S +IP K L P S + +
Sbjct: 1408 VVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPV 1467
Query: 327 ARK-----------SSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNIS---- 371
A S+S V S A S+ +PA G +S S P+ S L++I
Sbjct: 1468 ANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEG---TSIAISTPSEGSTALTSIPVSTT 1524
Query: 372 --KSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQ 429
S + PA+ + PV S + ++ + Q + S P
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVS--- 1581
Query: 430 WLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLS 489
SE++ L+ T ++SKT+V T + + + G S STP
Sbjct: 1582 --TMLVVSSEANTLSTTP--------IDSKTQV--TASTEASSSTTAEGSSMTISTPSEG 1629
Query: 490 R---AQRPQSCTSVGRV---TVHSTPVRRSSGPAPQSLLSARRVSALPTPA-------SR 536
P S T V T+ +TPV +S ++++ VS+ PTPA S
Sbjct: 1630 SPLLTSIPVSTTPVASPEASTLSTTPVDSNS-----PVITSTEVSSSPTPAEGTSMPTST 1684
Query: 537 RCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSR---LVDV 593
G P+T T+ + + S+ P NS T T + T S + +
Sbjct: 1685 YTEGRTPLTSITVRTTPVASSAISTL--STTPVDNSTPVTTSTEARSSPTTSEGTSMPNS 1742
Query: 594 SPDRGSPP------SRVP----QALNFSPEESDSTFSKSTATEVAREEAKPGGDAAP--- 640
+P G+ P S P +A S D++ +T+TE G + P
Sbjct: 1743 TPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTST 1802
Query: 641 -------------SEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSES 686
S L+ + + L+ TP ++ P++ + TP ++ + +
Sbjct: 1803 LSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATST 1861
Score = 45.8 bits (107), Expect = 1e-04
Identities = 121/544 (22%), Positives = 185/544 (34%), Gaps = 61/544 (11%)
Query: 177 PVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP----RESCTAHAASQAATQRKPG 232
P + +S SS A T P +S S T A+S+A+T
Sbjct: 594 PADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTP 653
Query: 233 TKLLLPRAASVRGRSIPGAAE----------KPKKEIPASPSRTKIPAEKE-SHRDVLP- 280
P S S AE + + + P T + A E S P
Sbjct: 654 VDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV 713
Query: 281 DKPAPGAVNVPAAGSHLGQGKRAIPVPN---------KLGLKKTLL-KAPGSTSNLARKS 330
D P + A+ S ++P + + KTLL + ST +
Sbjct: 714 DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLD 773
Query: 331 SSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPV 390
+S + + ++C SP + S S P+ S L++I S + L PV
Sbjct: 774 TSTHITTSTEASC-SPTTTEGTSMPI-STPSEGSPLLTSIPVSITPVTSPEASTLSTTPV 831
Query: 391 GASSWQAKRVDVSELAAE-QLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKT--- 446
++S +VS + T+ P+++ ++ +TP + A S S L+ T
Sbjct: 832 DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD 891
Query: 447 ------RSIRRRDSCLNSKTKVMPTPT-NQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTS 499
S R S S+ MPT T + P S+ PDS+TP +S R S T
Sbjct: 892 TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSM---PDSTTPVVSSEARTLSATP 948
Query: 500 VGRVTVHSTPVRRSSGPA-------PQSLLSARRVSALPTPASRR-CSGLPPMTPKTMPR 551
V T +T +S P P S S TP S + T T P
Sbjct: 949 VDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPV 1008
Query: 552 AVGSPLCVPARRRSSEP-RKNSAMRTEPTRESNRKTDSRLV--------DVSPDRGSPPS 602
+PL S P + ++M T E + V + S +P
Sbjct: 1009 DSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPAD 1068
Query: 603 RVPQALNFSPEESDSTFSKSTA--TEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAA 660
+S S ST + T+ T E + P S L+V + L+ TP
Sbjct: 1069 TSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDT 1128
Query: 661 SQPL 664
S P+
Sbjct: 1129 SIPV 1132
Score = 37.4 bits (85), Expect = 0.051
Identities = 71/328 (21%), Positives = 111/328 (33%), Gaps = 40/328 (12%)
Query: 348 VGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAA 407
V ++S ++ PA++S P++ S++G ++P S V VS +
Sbjct: 2350 VASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPV 2409
Query: 408 EQLTAPP-SASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTP 466
A S +P TP +SS +E T + +P
Sbjct: 2410 VSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEG-------------------TSIPTSP 2450
Query: 467 TNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGP-------APQ 519
++ P S+ P S+TP +S S T V T +T SS P P
Sbjct: 2451 PSEGTTPLASM---PVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPI 2507
Query: 520 SLLSARRVSALPTPASRRCSGLP-PMTPKTMPRAVGSPLCVPARRRSS-EPRKNSAMRTE 577
S S P S P T T P SP+ SS + ++M T
Sbjct: 2508 STASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTS 2567
Query: 578 PTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATE----VAREEAK 633
E + S V P S S L+ +P ++ + ST T A++ +
Sbjct: 2568 TYSEGSTPLRSMPVSTKPLASSEAS----TLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623
Query: 634 PGGDAAPSEALLVDIKLEPLAVTPDAAS 661
P + L I + + V AS
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEAS 2651
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 58.9 bits (141), Expect = 2e-08
Identities = 102/437 (23%), Positives = 162/437 (37%), Gaps = 40/437 (9%)
Query: 176 PPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKL 235
PP P + S +L + A +TR P P +A + T AS + T
Sbjct: 251 PPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASP----TGTPSRASLSMTPSTASLMR 306
Query: 236 LLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGS 295
+LPRA+ + K + AS SRT P R P + +P P+ S
Sbjct: 307 MLPRASPT---GMLSRTSLTKMDSTASISRT--PPRASITRT--PSRASP--TGKPSTAS 357
Query: 296 HLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSE 355
G RA P + T L + S + ++S S AS P ++S
Sbjct: 358 PTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPP-----RASP 412
Query: 356 FASIPANSSRPLSNISKSGRMGPAMLRPALP--AGPVGASSWQAKRVDVSELAAEQLTAP 413
+ S + + + R P P A P G S + Q TA
Sbjct: 413 TGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASP-------TGTQSTAS 465
Query: 414 PSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIP 473
P+ SP+ +P G + + + S +S L +T S R S ++ T T P
Sbjct: 466 PTGSPSTA-SPTGSPSTASPTGSPSRAS-LTRTPS---RASLTKMESTASITRTPSRASP 520
Query: 474 KFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRS--SGPAPQSLLSARRVSALP 531
++ + + +P + A S R + TP R S P+ SL + R S
Sbjct: 521 TWTPSTASPTGSPSTALAMGSPS-----RAALTRTPSRASLTRTPSRASLTTPSRASLTR 575
Query: 532 TPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLV 591
TP++ + +PP T + SP +P+ ++ +++ P R S +T R
Sbjct: 576 TPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRAS 635
Query: 592 DV-SPDRGSPPSRVPQA 607
+P R SP P+A
Sbjct: 636 PTGTPPRASPTGTPPRA 652
Score = 52.4 bits (124), Expect = 2e-06
Identities = 122/551 (22%), Positives = 189/551 (34%), Gaps = 69/551 (12%)
Query: 171 SPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRK 230
S ++ P + SS L + + A L R P LPR A+ R+
Sbjct: 66 SLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPR----------ASLMRR 115
Query: 231 PGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNV 290
P T A+ R S P + + T S + P
Sbjct: 116 PST------ASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMT 169
Query: 291 PAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGK 350
P+ S RA P T + + S + + +S S AS T P
Sbjct: 170 PSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASP 229
Query: 351 AKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQL 410
S AS+ S L ++R A P G S R ++++ +
Sbjct: 230 TGSPPRASLSMMPSTAL------------LIRTPPRASPTGMLS----RTSLTKMDS--- 270
Query: 411 TAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSK---TKVMPTPT 467
TA + +P++P T G +S + + S+ R + + S+ TK+ T +
Sbjct: 271 TASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTAS 330
Query: 468 NQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSL-LSARR 526
P+ SI +P ++P +P + + G TP R S +P + L+
Sbjct: 331 ISRTPPRASITRTPSRASP----TGKPSTASPTG------TPSRASPTGSPSTASLTGLS 380
Query: 527 VSALPTPASRRCSGLPPMTPKTM------PRAVGSPLCVPARRRSSEPRKNSAMRTEPTR 580
+A PT R S P TP T PRA SP + +R ++ ++ P R
Sbjct: 381 STASPTGTPPRAS--PTGTPSTASLTRKPPRA--SPTGMLSRTSITKMDSTASPTRTPPR 436
Query: 581 ESNRKTDSRLVDV-SPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDA- 638
S T R +P R SP A SP S ST S + + A P +
Sbjct: 437 ASPTGTPPRASPTGTPSRASPTGTQSTA---SPTGSPSTASPTGSPSTASPTGSPSRASL 493
Query: 639 --APSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNT 696
PS A L ++ + + P +P +A+GS SR +T T
Sbjct: 494 TRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRA---ALTRT 550
Query: 697 PDMNKNVAKPS 707
P PS
Sbjct: 551 PSRASLTRTPS 561
Score = 44.7 bits (104), Expect = 3e-04
Identities = 122/602 (20%), Positives = 191/602 (31%), Gaps = 96/602 (15%)
Query: 176 PPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKP---G 232
PP + S +L S ++A LTR + S S A+ +R P
Sbjct: 53 PPRASLKGTTSMASLMVSPSRASLTR----------MQSSSLLTRTPSMASLKRMPPRAS 102
Query: 233 TKLLLPRAASVRGRSIPGAAEKPKK-EIPASPSRTKIPAEKE--------SHRDVLPDKP 283
LPRA+ +R S P + + +PSR + S + P
Sbjct: 103 RTRTLPRASLMRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPP 162
Query: 284 APGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSAC 343
P+ S RA P T + + S + + +S S AS
Sbjct: 163 RASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTG 222
Query: 344 TSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGA-SSWQAKRVDV 402
T P S AS+ S L ++R A P G S ++D
Sbjct: 223 TPPRASPTGSPPRASLSMMPSTAL------------LIRTPPRASPTGMLSRTSLTKMDS 270
Query: 403 SELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAW--------SESSQLNKTRSIRRRDS 454
+ + P +ASPT TP + S A S + L++T S+ + DS
Sbjct: 271 TASITRTPSRPSTASPTG--TPSRASLSMTPSTASLMRMLPRASPTGMLSRT-SLTKMDS 327
Query: 455 CLN-----SKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHS-- 507
+ + + TP+ K S SP + + S P + + G + S
Sbjct: 328 TASISRTPPRASITRTPSRASPTGKPSTA-SPTGTPSRASPTGSPSTASLTGLSSTASPT 386
Query: 508 -TPVRRSSGPAPQSLLSAR------------------------------RVSALPTPASR 536
TP R S P + R R S TP
Sbjct: 387 GTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRA 446
Query: 537 RCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPD 596
+G P T ++ SP P+ + ++ P+R S +T SR +
Sbjct: 447 SPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKME 506
Query: 597 RGSPPSRVPQALN--FSPEESDSTFSKSTA--------TEVAREEAKPGGDAAPSEALLV 646
+ +R P + ++P + T S STA + R ++ PS A L
Sbjct: 507 STASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLT 566
Query: 647 DIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKP 706
L TP + P P G S L+ M +T + + +
Sbjct: 567 TPSRASLTRTPSTVLLTRMP-PSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRA 625
Query: 707 SP 708
SP
Sbjct: 626 SP 627
Score = 31.6 bits (70), Expect = 2.8
Identities = 55/261 (21%), Positives = 94/261 (36%), Gaps = 24/261 (9%)
Query: 464 PTPTNQFKIPKFSIGDSPDSSTP-KLSRAQRPQSCTSVG---RVTVHSTPVRRSS----- 514
PT T P + + + TP + S P + + +G R ++ TP R S
Sbjct: 4 PTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTS 63
Query: 515 ------GPAPQSLLSARRVSALP-TPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSE 567
P+ SL + S L TP+ +PP +T S + P+ +
Sbjct: 64 MASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTR 123
Query: 568 PRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEV 627
+++ T P+R S T S + + PSR +L +P + T + STA+ +
Sbjct: 124 SPSRASLTTTPSRASLSMTPSTAAAL-----TMPSRA--SLTRTPPRASLTMTPSTAS-L 175
Query: 628 AREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESR 687
R + PS + D+ + L TP GS R
Sbjct: 176 TRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPR 235
Query: 688 PLIDLMTNTPDMNKNVAKPSP 708
+ +M +T + + + SP
Sbjct: 236 ASLSMMPSTALLIRTPPRASP 256
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.5 bits (140), Expect = 2e-08
Identities = 129/529 (24%), Positives = 184/529 (34%), Gaps = 98/529 (18%)
Query: 192 SSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGA 251
S+GA+ R T P P + A+ R S R GT++ LPR A P A
Sbjct: 157 SAGAR-RDTSGPTPGTPSPAMARRS------------RAAGTEVGLPRPA-------PSA 196
Query: 252 AEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLG 311
+P E P ++ A + S + P+P A P+AG L + P L
Sbjct: 197 RPRPPTE---GPRKSVSSASEHSTTE-----PSPAARRRPSAGGGLQR-----PASRSLS 243
Query: 312 LKKTLLKAPGSTSNLARKSSSGPVWSGASS-----ACTSPAVGKAKSSEFASIPANSSRP 366
T L +P + AR + P A P V + ++ SS P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 367 LSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSAS--PTQPQTP 424
L+ S S + + P LPA P +SS + LA +APPS P+ P TP
Sbjct: 304 LATPSPSAAL-QSQAPPTLPATP-HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361
Query: 425 EGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSS 484
+ + S L T S L+ P +P SP +S
Sbjct: 362 P------SQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALPPLQAPPSPPAS 414
Query: 485 TPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPM 544
P LS P S + + VH S P+P P A PP+
Sbjct: 415 PP-LSPLATP-SPQAPNALAVHLLQAPFSPPPSP------------PVQAPFSPPASPPV 460
Query: 545 TPKTMPRA------VGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRG 598
+P P + PL VP +S P SA T P + L P
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA--TPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 599 SPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPG-GDAAPSEALLVDIKLEPLAVTP 657
+PP+ L P S PG +PS +L + PLA TP
Sbjct: 519 APPALATPPLQALPSPPASF---------------PGQAPFSPSASL----PMSPLA-TP 558
Query: 658 DAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKP 706
+ P++ PL+ +P A + + RP TP + +V+ P
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRP------PTPGPDTSVSGP 601
Score = 38.9 bits (89), Expect = 0.017
Identities = 105/458 (22%), Positives = 163/458 (35%), Gaps = 102/458 (22%)
Query: 280 PDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSS--SGPVWS 337
P P P PAA R + +G K +A G +S+ +GP S
Sbjct: 30 PGSPRPPPPVTPAA-------LRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS 82
Query: 338 GASS----ACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGAS 393
+S A PA G+ + + PA ++ P +S GR RP GP+G
Sbjct: 83 AGTSSRNPASRPPASGRGERAP----PAKNTSP-GPVSSPGRAS-GTTRP----GPLGQK 132
Query: 394 SWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRD 453
+ ++AE+ A A+ ++ G RRD
Sbjct: 133 GLR--------ISAEETVARGKATEAPKRSALSAGA---------------------RRD 163
Query: 454 SCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRS 513
+ + T P+P + + S + P+ + + RP+ T R +V S +
Sbjct: 164 T--SGPTPGTPSPA----MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 514 SGPAPQSLLSARRVSALPTPASR--RCSGLPPMTP-KTMPRAVGSPLCVPARRRSSEPRK 570
+ P+P + L PASR S P +P ++ P A G+P PA +P+
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR-APAHPSQPKPKG 276
Query: 571 NSAMR----TEPTRES----NRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKS 622
A+R T P +++ + S L SP + S+ P L +P S T +
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-AALQSQAPPTLPATPHSSSLTCQLA 335
Query: 623 TATEVA--REEAKPGGDAAPS---------------------EALLVDIKLEPLAVTPDA 659
T +A A P PS + L L PLA TP
Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPP 394
Query: 660 ASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTP 697
+ P + LP + +P A S PL L T +P
Sbjct: 395 QAPPALALPPLQAPPSPPA-------SPPLSPLATPSP 425
Score = 32.7 bits (73), Expect = 1.2
Identities = 100/440 (22%), Positives = 136/440 (30%), Gaps = 64/440 (14%)
Query: 174 LGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGT 233
L PP P ++PAL + T +P + A P T H++S P
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLP 339
Query: 234 KLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKP-APGAVNVPA 292
+A +++P P + S + A LP P +P A P
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT----HSFLPSPPLSPLATPPPQ 395
Query: 293 AGSHLGQGKRAIP--VPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGK 350
A L P P L +P + + LA P S SP V +
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-----SPPPSPPV-Q 449
Query: 351 AKSSEFASIPAN-SSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAE- 408
A S AS P + S+ P S S P + P+ PA P + S LAA
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 409 -QLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPT 467
QL PP +P TP + +P+P
Sbjct: 510 LQLAKPPPQAPPALATP----------------------------------PLQALPSPP 535
Query: 468 NQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRV 527
F SP +S P A P V + P S PA +L + RR
Sbjct: 536 ASF---PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP---PSPPASPTLQAPRRP 589
Query: 528 SALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTD 587
PTP P +T P P P+ S + T E R D
Sbjct: 590 ---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 646
Query: 588 SRLVDVSPDRGSPPSRVPQA 607
S P+ G+ S P A
Sbjct: 647 S-----GPEGGAAASPPPDA 661
Score = 30.8 bits (68), Expect = 4.7
Identities = 74/288 (25%), Positives = 99/288 (34%), Gaps = 48/288 (16%)
Query: 168 LSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGP-PHSAHALPRESCTAHAASQAA 226
L+ P PPV LL P+ P+S R P P P ++ + PR +
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614
Query: 227 TQRKPGTKLLLP------RAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKE---SHRD 277
R P + L P +A+ + G P+ ASP P + E H
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP-----PPDAELAACHPA 669
Query: 278 VLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLAR-KSSSGPVW 336
PAP A G+ L P P G PGS L + GP
Sbjct: 670 AWSRGPAPPLAFRGAPGAPL-------PWPPATG--------PGSADGLCTIYETEGPES 714
Query: 337 S----GASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGA 392
+ GA SP K++ A A+S P K R+G LP G + A
Sbjct: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP-----KQARLG------ELPLGALQA 763
Query: 393 SSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSES 440
S Q LAA + A S P EGGG + A S++
Sbjct: 764 SVVQHLLSRTLLLAAAEGAA--GGSGGGPGGAEGGGVTGGARAALSDA 809
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 58.2 bits (139), Expect = 3e-08
Identities = 112/483 (23%), Positives = 158/483 (32%), Gaps = 108/483 (22%)
Query: 175 GPPVGEPRLLAS-----SPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQR 229
GP PRLL SP L ++ A P PP A + +ES A + +Q
Sbjct: 574 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPP--ARSPSQESIGARSRGSGHSQE 631
Query: 230 KPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAV- 288
+P + + + R++P E+P K + P + P + P PAPG
Sbjct: 632 QPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGP-PPYVFMYPQGSPSSPAPGPPP 690
Query: 289 NVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACT---- 344
P A S+L P P + + L PG T A + GPV S S T
Sbjct: 691 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR 750
Query: 345 ---------------SPAVGKAKSSEFA------SIPANSSRPLSNIS------------ 371
+PA G +S FA P + LS++S
Sbjct: 751 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES 810
Query: 372 ---KSGRMGP---AMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPS---------- 415
K G GP + PA P+ P G + D E PPS
Sbjct: 811 PGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPF 870
Query: 416 --------------ASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRD---SCLNS 458
A P +TP G N + ES + + R R+ + L +
Sbjct: 871 AEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLT----ESDTVKRRPKCREREPLQTALLA 926
Query: 459 KTKVMPTPTNQFKIPKFSIGDSPDSST---PKLSRAQRPQSCTSVGRVTVHSTPVRRSSG 515
TP +P + G+SP +S+ P+ S T + PV G
Sbjct: 927 FGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG 986
Query: 516 P------------------APQSLLSARRVSALPTPASRRCSGL----PPMTPKTMPRAV 553
P AP +LL P P S C+ L P + P+ PR V
Sbjct: 987 PGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPV 1046
Query: 554 GSP 556
P
Sbjct: 1047 PPP 1049
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 58.2 bits (139), Expect = 3e-08
Identities = 112/483 (23%), Positives = 158/483 (32%), Gaps = 108/483 (22%)
Query: 175 GPPVGEPRLLAS-----SPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQR 229
GP PRLL SP L ++ A P PP A + +ES A + +Q
Sbjct: 656 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPP--ARSPSQESIGARSRGSGHSQE 713
Query: 230 KPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAV- 288
+P + + + R++P E+P K + P + P + P PAPG
Sbjct: 714 QPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGP-PPYVFMYPQGSPSSPAPGPPP 772
Query: 289 NVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACT---- 344
P A S+L P P + + L PG T A + GPV S S T
Sbjct: 773 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR 832
Query: 345 ---------------SPAVGKAKSSEFA------SIPANSSRPLSNIS------------ 371
+PA G +S FA P + LS++S
Sbjct: 833 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES 892
Query: 372 ---KSGRMGP---AMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPS---------- 415
K G GP + PA P+ P G + D E PPS
Sbjct: 893 PGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPF 952
Query: 416 --------------ASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRD---SCLNS 458
A P +TP G N + ES + + R R+ + L +
Sbjct: 953 AEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLT----ESDTVKRRPKCREREPLQTALLA 1008
Query: 459 KTKVMPTPTNQFKIPKFSIGDSPDSST---PKLSRAQRPQSCTSVGRVTVHSTPVRRSSG 515
TP +P + G+SP +S+ P+ S T + PV G
Sbjct: 1009 FGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG 1068
Query: 516 P------------------APQSLLSARRVSALPTPASRRCSGL----PPMTPKTMPRAV 553
P AP +LL P P S C+ L P + P+ PR V
Sbjct: 1069 PGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPV 1128
Query: 554 GSP 556
P
Sbjct: 1129 PPP 1131
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 56.6 bits (135), Expect = 8e-08
Identities = 135/587 (22%), Positives = 205/587 (34%), Gaps = 107/587 (18%)
Query: 193 SGAQARL--TRAPG-----PPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRG 245
+GA AR RAPG PP S P T A G K L RA + G
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPR--PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 246 RSIPGAAEKPKKEIPASPSRT-KIPAEKESHRDVLPDKPAPGAVNVPAAGSH------LG 298
+IP +A + A P+RT + PA R +PG V+ P S LG
Sbjct: 68 ATIPESAPR------AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 299 QGKRAIPVPNKLGLKKTLLKAP--GSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEF 356
Q I + K +AP + S AR+ +SGP + SPA+ + +
Sbjct: 122 QKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGP-----TPGTPSPAMARRSRAAG 175
Query: 357 ASI----PANSSRPL-------SNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSEL 405
+ PA S+RP ++S + PA P Q
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 406 AAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPT 465
+A L++P + P+ TP + + L R + ++ + P
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAH-----PSQPKPKGLQALRPPQVTPPRKDAAPALGPL 290
Query: 466 PTNQFKIPKFSIGDSPDSSTPKLSRAQRP------QSCTSVGRVTVHST-------PVRR 512
++ P S SP S+ P L P Q+ TS+G T+ +T P+
Sbjct: 291 SSSPLATPSPSAPPSP-SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 513 SSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSP-----LCVPARRRSSE 567
+ P PQ+ A + L P S PP +P P A SP L V +
Sbjct: 350 LATPPPQAP-PALALPPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Query: 568 PRKNSAMR---TEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTA 624
P + ++ + P + + P +PP +VP + SP S S A
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462
Query: 625 TEVAR----EEAKPGGDAAPSEAL---------------------LVDIKLEPLAVTPDA 659
+ AKP A P+ A + + PLA TP
Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA-TPPP 521
Query: 660 ASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKP 706
+ P++ PL+ +P A + + RP TP + +V+ P
Sbjct: 522 QAPPVLAAPLLQVPPSPPASPTLQAPRRP------PTPGPDTSVSGP 562
Score = 41.2 bits (95), Expect = 0.004
Identities = 125/584 (21%), Positives = 193/584 (33%), Gaps = 129/584 (22%)
Query: 115 SSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLL 174
SS +A+ +P +G+ +E+ + E K S +R+T
Sbjct: 106 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS-AGARRDTS-------- 156
Query: 175 GPPVGEP--------RLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQA- 225
GP G P R + LP AR P PP S + H+ ++
Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPS 212
Query: 226 -ATQRKP--GTKLLLPRAASVRGRSIP-------GAAEKPKKEIPASPSRTKIPAEKESH 275
A +R+P G L P + S+ + P G + + PA PS+ K P ++
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-PKGLQAL 271
Query: 276 R--DVLPDKPAPGAVNVPAAGSHLGQ-GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSS 332
R V P + P + S L A P P+ +TL P + + A S
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331
Query: 333 GPVWSGASSACTSPAVGKAKSSEFASIPA------------NSSRPLSNISKSGRMGPAM 380
P S SP + + + PA +S PLS ++ P
Sbjct: 332 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 391
Query: 381 LRPAL-------------------PAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQP 421
L L PA P + S LAA L PPS + P
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 451
Query: 422 QTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSP 481
+P TP Q P
Sbjct: 452 MSPSA--------------------------------------TPPPQ---------APP 464
Query: 482 DSSTPKLSRAQ-RPQSCTSVGRVTVHSTPVRRSS--GPAPQSLLSARRVSALPTPASRRC 538
+ P L A+ PQ+ ++ + + P +S G AP S ++ +S L TP +
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-- 522
Query: 539 SGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRG 598
PP+ + + SP PA PR+ + + R T + ++P
Sbjct: 523 --APPVLAAPLLQVPPSP---PASPTLQAPRRPPTPGPDTSVSGPRLT----LALAPGPP 573
Query: 599 SPPSRVPQALNFSPE-ESDSTFSKSTATEVAREEAKPGGDAAPS 641
PPSR P + P+ S+ + ST E+ ++ P G AA S
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 617
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 56.6 bits (135), Expect = 8e-08
Identities = 134/577 (23%), Positives = 208/577 (36%), Gaps = 67/577 (11%)
Query: 181 PRLLASSPA-LPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLL--L 237
P+ L +PA P+ G +A P P S + + AAT PG +L +
Sbjct: 833 PQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSV 892
Query: 238 PRAASVRGRSI-PGAAEKPKKEIPASPSRTKIP--AEKESHRDVLPDKPAP---GAVNVP 291
P A + +S+ P A P P + +P A S R +P P +VP
Sbjct: 893 PSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVP 952
Query: 292 AAGSHLGQGK----RAIPVPNKLGLKKTLLKA--PGSTSNLAR---KSSSGPVWSGASSA 342
K +PV GL L A PG TS + SS+ + ++
Sbjct: 953 VQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGG 1012
Query: 343 CTSPAVGKAKSSEFASIPANSSRPLSNISKS----GRMGPAMLRPALPAGPVGASSWQAK 398
P SS+ ++ S P S+++ G GPA ++P L AG A
Sbjct: 1013 HALPLGTSPASSQAGTV--TSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQ--APLLAPG 1068
Query: 399 RVDVSELAAEQLTAPPSASPTQPQTPE--GGGQWLNSSCAWSESSQLNKTRSIRRRDSCL 456
+V VS + + QL P A+P P G SS ++ SQ + S
Sbjct: 1069 QVGVSPVPSPQLP-PACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTT 1127
Query: 457 NSKTKVMP---------TPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHS 507
++P TP P + G S ++ P++ V + + S
Sbjct: 1128 PPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKV-KAAIAS 1186
Query: 508 TPVRRSS-------GPAPQSLLSARRVSALPTPAS----RRCSGLPPMTPKTM-PRAVGS 555
PV GPAP+ L V P S + PP P+T P A S
Sbjct: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSS 1246
Query: 556 P-LCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEE 614
P L PA R+S + P+ S+ + + ++ + +PPS P
Sbjct: 1247 PPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGS 1306
Query: 615 SDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCD 674
S+S+ ++ R+EA G V ++ PL T D+ + L +DF
Sbjct: 1307 SESSSGRAAGDTPERKEAAGTGKK-------VKVRPPPLKKTFDSVDNRV--LSEVDF-- 1355
Query: 675 TPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVG 711
E A E RP + + +P + P ++G
Sbjct: 1356 --EERFAELPEFRP--EEVLPSPTLQSLATSPRAILG 1388
Score = 33.5 bits (75), Expect = 0.73
Identities = 56/302 (18%), Positives = 87/302 (28%), Gaps = 32/302 (10%)
Query: 171 SPLLGP------PVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQ 224
+PLL P PV P+L + A A + +P P SA
Sbjct: 1062 APLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYT 1121
Query: 225 AATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPA 284
AT P +LP+ + P S + + + + + P K
Sbjct: 1122 VATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVK 1181
Query: 285 PGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACT 344
++P G R P P ++ L P G A
Sbjct: 1182 AAIASIPVGSFEAGASGRPGPAP-----RQPLEPGPVREPTAPESELEGQPTPPAPPPLP 1236
Query: 345 SPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSE 404
A+SS PA ++ GP + P+ +S W+ +
Sbjct: 1237 ETWTPTARSSPPLPPPAE--------ERTSAKGPETMASKFPS---SSSDWRVPGQGLEN 1285
Query: 405 LAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMP 464
+ PPS +P P G + S S + R+ + K KV P
Sbjct: 1286 RG--EPPTPPSPAPAPAVAPGGSSE--------SSSGRAAGDTPERKEAAGTGKKVKVRP 1335
Query: 465 TP 466
P
Sbjct: 1336 PP 1337
Score = 33.1 bits (74), Expect = 0.95
Identities = 94/415 (22%), Positives = 140/415 (33%), Gaps = 65/415 (15%)
Query: 171 SPLLGPPVGEPRLLASSPALPSS----GAQARLTRAPGPPHSAHALPRESCTAHAASQAA 226
S + PP G +L + P+ G AR+ AP P A+ P + AA+
Sbjct: 615 SVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPS-LAYGAPAAPLSRPAATMVT 673
Query: 227 TQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPG 286
+P + +P A+ S G AE ASP+ T A + P
Sbjct: 674 NVVRPVSSTPVPIASKPFPTS--GRAE-------ASPNDT---AGARTEMGTGSRVPGGS 721
Query: 287 AVNVPAAGSHLGQGKRAIPVPNKLG--LKKTLLKAPGSTSNLARKSSSGPVWSGASSACT 344
+ V S P P+ + L T+ KAP + +NL V + A
Sbjct: 722 PLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLL-------VGTPGYGAPA 774
Query: 345 SPAVGK-AKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVS 403
PAV A+ + A S SG GP L P G +G + + +
Sbjct: 775 PPAVQFIAQGAPGGGTTAGSGAGAG----SGPNGPVPLGILQP-GALGKAGGITQVQYIL 829
Query: 404 ELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVM 463
+QL P+ +P P T + A S + R + N K
Sbjct: 830 PTLPQQLQVAPAPAPA-PGT---------KAAAPSGPAPTTSIRFTLPPGTSTNGKVLAA 879
Query: 464 PTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSV----GRVTVH----STPVRRSSG 515
PT I + S+ +P +S Q P S G+V V S VR
Sbjct: 880 TAPTPGIPILQ-SVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGA 938
Query: 516 PAPQSLLS--------------ARRVSALPTPASRRCSGLPPMTPKTMPRAVGSP 556
P L+S ++ + P P S +PP++P T+P P
Sbjct: 939 GQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQP 993
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 56.6 bits (135), Expect = 8e-08
Identities = 117/540 (21%), Positives = 181/540 (33%), Gaps = 64/540 (11%)
Query: 172 PLLGPPVGEPRLLASSPALPSSGAQARLTR-APGPPHSAHALPRESCTAHAASQAAT--Q 228
P PP G P A++P P + AP PP P+ + T A + ++
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 229 RKPGTKL-LLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKP--AP 285
P +K P AA+ + P K PA PS P + V+P P AP
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS----PKGDPTSPAVIPLSPKKAP 1416
Query: 286 GAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTS 345
+ +G P + LKK AP +++ GP + T
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKK----APATSA-----PKGGPATPSSKGDPTL 1467
Query: 346 PAVGKAKSSEFASIP--ANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVS 403
PAV E + A SS P + MG L +P+ P + + R D
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 404 ELAAEQLT--APPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTK 461
A L+ P + +P + P A + S KT
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPP----------AMTVPSP---------------KKTP 1562
Query: 462 VMPTPTNQFKIPKFSIGDSPDSSTPKLSR-AQRPQSCTSVGRVTVHSTPVRRSSGPAPQS 520
+PTP P SP + TP + A P+ VT S P P +
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP----KEAPTPPA 1618
Query: 521 LLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTR 580
+ TPA + PP+TP ++ + SP V + ++ P+ + + +
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 581 ESNRKT------DSRLVDVSPDRGSPPSRVPQALN--FSPEESDSTFSKSTATEVAREEA 632
+ ++ +S + +P R P ++ A + P+ S SK + VA
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL 1738
Query: 633 KPGGDAAPSEALLVDIKLE---PLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPL 689
P + A D PLA AS PL PE+ + S P+
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV 1798
Score = 53.9 bits (128), Expect = 5e-07
Identities = 126/565 (22%), Positives = 188/565 (33%), Gaps = 70/565 (12%)
Query: 171 SPLLGP-PVGEPRLLASSPALPSSG-AQARLTRAPGPPHSAHALPRESCTAHAASQAATQ 228
SP P P G P A++ P G A L AP PP + P+ AT
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG--------PATP 1097
Query: 229 RKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAV 288
G + P AA+ G A P K P +P+ T S + L P GA
Sbjct: 1098 SPKGAPM--PPAATPPSPK-GGLATPPHKGAPTTPAATP-----PSPKGGLATPPPKGAP 1149
Query: 289 NVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGS-TSNLARKSSSGPVWSGASSACTSPA 347
PAA +G A P P G T P S LA S G + A++ SP
Sbjct: 1150 TTPAATPPSPKGGLATPPPK--GAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSPK 1206
Query: 348 VGKAKSSEFASIPANSSRPLS---NISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSE 404
G A S + ++ P S ++ G A P P G +
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA---------- 1256
Query: 405 LAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMP 464
T PP +PT P + ++ + + S K P
Sbjct: 1257 ------TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 465 TPTNQF-KIPKFSIGDSP--DSSTPKLSRAQRPQSCTSVGRVTVHS-----TPVRRSSGP 516
TP PK S G P + TP P+ ++ T S TP +
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370
Query: 517 APQSLLSARRVSALPTPASRRCSGLP-----PMTPKTMPRAVGSPLCVPARRR-SSEPRK 570
P + S + A+ P+ +R +P P +P +P + P R ++ P K
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430
Query: 571 NSAMRTEPTRESNRKTDSRLVDVSPDRGSPPS-------RVPQALNFSPEESDSTFSKST 623
T S +K + S +G P + +P SP+E + +T
Sbjct: 1431 GDLTPPAVTPVSLKKAPA----TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486
Query: 624 ATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVG 683
++ + A P AP+ ++ + + TP + P+ + TP A
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP----ATL 1542
Query: 684 SESRPLIDLMTNTPDMNKNVAKPSP 708
+ LI P K A P+P
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTP 1567
Score = 43.1 bits (100), Expect = 0.001
Identities = 119/530 (22%), Positives = 175/530 (33%), Gaps = 96/530 (18%)
Query: 177 PVGEPRLLASSPALPSSGAQARLTRAPGPPHSAH-------------ALPRESC------ 217
P+G+P +SP +S A T + P SA A P ES
Sbjct: 600 PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVA 659
Query: 218 --TAHAASQAATQRKP---GTKLLLPRAASVRGRS------IPGAAEK----PKKEIPAS 262
TA S T P GT L P+ V+ + +P A+E P + +
Sbjct: 660 PTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCA 719
Query: 263 PSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGS 322
P T + A + +P P A P G + P K+ + G+
Sbjct: 720 PLATLVLAPEIPKS--VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGA 777
Query: 323 TSNLARKS-------SSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKS-- 373
++ + K S P+ S P K + I N S P+S + S
Sbjct: 778 SATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI-GNLSSPVSPVEASFL 836
Query: 374 ---------GRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQ---- 420
+ PA P P GA + A V+ L+ + +T PP +PT
Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA----VTPLSPKGVTLPPKETPTPSVVN 892
Query: 421 -PQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGD 479
P EG ++ A ++ L+ T S + K + P P P
Sbjct: 893 LPFPKEGP-----ATPAPKQAPALSMTSSSPK-------KARATPAPKGIPASPSPKGAP 940
Query: 480 SPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTP------ 533
+P ++TP + +TP GPA S A A P
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000
Query: 534 ASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDV 593
A+ G P T P GSP P + +S P T P+ + +
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP----PAATPPSPKGSPAA------T 1050
Query: 594 SPDRGSPPSRVPQALNFSPEESDSTFS-KSTATEVAREEAKP-GGDAAPS 641
+G+P + P A SP+ +T S K T A P GG A PS
Sbjct: 1051 PLPKGAPTT--PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098
Score = 30.0 bits (66), Expect = 8.1
Identities = 43/203 (21%), Positives = 74/203 (36%), Gaps = 25/203 (12%)
Query: 184 LASSPALPSSGAQARLTRAPGPPHSAHA--LPRESCTAHAASQAATQRKPGTKLLLPRAA 241
+A +P LP ++ + HS P ES + + AA ++ L P +A
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKV----LPKPESA 1788
Query: 242 SVRGRSIPGA----AEKPKKEIPA--------------SPSRTKIPAEKESHRDVLPDKP 283
SV P A P +P SPS+ PA+++ ++P +P
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
Query: 284 APGAVNVPAAGSHLGQGKRA-IPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSA 342
G V + ++ K A IPVP + GS + S + S+
Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQ 1908
Query: 343 CTSPAVGKAKSSEFASIPANSSR 365
T+ A ++E P + ++
Sbjct: 1909 ATTQQAQLAAAAEIDEEPVSKAK 1931
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 55.5 bits (132), Expect = 2e-07
Identities = 113/503 (22%), Positives = 179/503 (35%), Gaps = 95/503 (18%)
Query: 205 PPHSAHALPRESCTAHAASQAATQRK-PGTKLLLPRAA----SVRGRSIPGAAEKPKKEI 259
PP + L + C A T+ + P K P A ++ P P E
Sbjct: 523 PPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSET 582
Query: 260 PASP--------SRTKIPAEKESHRDVLPD---KPAPGAVNVPAAGSHLGQGKRAIP--- 305
A+P ++T+ ++SH + L D AP + P + G+ K ++P
Sbjct: 583 EATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGK-KCSLPAEE 641
Query: 306 --VPNKLGLKKTLLKAPGS----TSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASI 359
V KLG +K P TS +AR PV SG + T+P + E
Sbjct: 642 DSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTP-----PNKELPPS 696
Query: 360 PANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPT 419
P ++PL+ P S+ +AK P++ P
Sbjct: 697 PEKKTKPLATTQ-----------------PAKTSTSKAK-------------TQPTSLPK 726
Query: 420 QPQTPEGGG---QWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFS 476
QP GG + ++ + ++ + R S L SK V P P K P+
Sbjct: 727 QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK-DVKPKPIADAKAPEKR 785
Query: 477 IGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASR 536
S +S P SR+ + T T + S +P +LL + P +
Sbjct: 786 ASPSKPASAP-ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-------PTAI 837
Query: 537 RCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAM------------RTEPTRESNR 584
+ G P K ++V + L P +S +K + + R + T +R
Sbjct: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSR 897
Query: 585 KTDSRLVDVSPDRGSPPSRVPQ----ALNFSPEESDSTFSKSTATEVAREEAKPGGDAA- 639
+ + +D P P S P+ A N S + + SK +TE + + PGG A
Sbjct: 898 PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ--PGGGRAK 955
Query: 640 ---PSEALLVDIKLEPLAVTPDA 659
+EA K E AVT A
Sbjct: 956 VEKKTEAAATTRKPESNAVTKTA 978
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
sapiens]
Length = 1152
Score = 55.5 bits (132), Expect = 2e-07
Identities = 113/503 (22%), Positives = 179/503 (35%), Gaps = 95/503 (18%)
Query: 205 PPHSAHALPRESCTAHAASQAATQRK-PGTKLLLPRAA----SVRGRSIPGAAEKPKKEI 259
PP + L + C A T+ + P K P A ++ P P E
Sbjct: 523 PPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSET 582
Query: 260 PASP--------SRTKIPAEKESHRDVLPD---KPAPGAVNVPAAGSHLGQGKRAIP--- 305
A+P ++T+ ++SH + L D AP + P + G+ K ++P
Sbjct: 583 EATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGK-KCSLPAEE 641
Query: 306 --VPNKLGLKKTLLKAPGS----TSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASI 359
V KLG +K P TS +AR PV SG + T+P + E
Sbjct: 642 DSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTP-----PNKELPPS 696
Query: 360 PANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPT 419
P ++PL+ P S+ +AK P++ P
Sbjct: 697 PEKKTKPLATTQ-----------------PAKTSTSKAK-------------TQPTSLPK 726
Query: 420 QPQTPEGGG---QWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFS 476
QP GG + ++ + ++ + R S L SK V P P K P+
Sbjct: 727 QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK-DVKPKPIADAKAPEKR 785
Query: 477 IGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASR 536
S +S P SR+ + T T + S +P +LL + P +
Sbjct: 786 ASPSKPASAP-ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-------PTAI 837
Query: 537 RCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAM------------RTEPTRESNR 584
+ G P K ++V + L P +S +K + + R + T +R
Sbjct: 838 KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSR 897
Query: 585 KTDSRLVDVSPDRGSPPSRVPQ----ALNFSPEESDSTFSKSTATEVAREEAKPGGDAA- 639
+ + +D P P S P+ A N S + + SK +TE + + PGG A
Sbjct: 898 PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ--PGGGRAK 955
Query: 640 ---PSEALLVDIKLEPLAVTPDA 659
+EA K E AVT A
Sbjct: 956 VEKKTEAAATTRKPESNAVTKTA 978
>gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
Length = 333
Score = 54.7 bits (130), Expect = 3e-07
Identities = 87/355 (24%), Positives = 132/355 (37%), Gaps = 65/355 (18%)
Query: 25 KEDILLLADEKFDFD-LSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPT 83
+ED+ + DE DF LS S S ED V P R ++ + N P +
Sbjct: 5 EEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRL 64
Query: 84 SESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKL 143
S PL+ EK E+ EA+ LA +E + A + PR
Sbjct: 65 S-----LGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPR------------- 106
Query: 144 KINLFEKEKEMKKSPTSLKRETYYLSDSPL--LGPPVGEPRLLASSPALPSSGAQARLTR 201
+K SP +RET+ L DSP+ L P V L S+P+ S + R
Sbjct: 107 ---------RVKPSP---RRETFVLKDSPVRDLLPTVNS--LTRSTPSPSSLTPRLRSND 152
Query: 202 APGPPHSAHA--------LPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPG--A 251
G + A + RES T + + P + L VRGR+ P A
Sbjct: 153 RKGSVRALRATSGKRPSNMKRESPTCNL---FPASKSPASSPLTRSTPPVRGRAGPSGRA 209
Query: 252 AEKPKKEI-------PASPSRTKIP-----AEKESHRDVLPDKPAPGAVNVPAAGSHLGQ 299
A P I P++ + ++P A K S + +P A +P +
Sbjct: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
Query: 300 GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSS 354
G+ A+P P+ L +K L + + + PV S P +G +S+
Sbjct: 270 GRGALP-PDSLSTRKGLPRPSTAGHRVRESGHKVPV----SQRLNLPVMGATRSN 319
>gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
Length = 333
Score = 54.7 bits (130), Expect = 3e-07
Identities = 87/355 (24%), Positives = 132/355 (37%), Gaps = 65/355 (18%)
Query: 25 KEDILLLADEKFDFD-LSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPT 83
+ED+ + DE DF LS S S ED V P R ++ + N P +
Sbjct: 5 EEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRL 64
Query: 84 SESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKL 143
S PL+ EK E+ EA+ LA +E + A + PR
Sbjct: 65 S-----LGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPR------------- 106
Query: 144 KINLFEKEKEMKKSPTSLKRETYYLSDSPL--LGPPVGEPRLLASSPALPSSGAQARLTR 201
+K SP +RET+ L DSP+ L P V L S+P+ S + R
Sbjct: 107 ---------RVKPSP---RRETFVLKDSPVRDLLPTVNS--LTRSTPSPSSLTPRLRSND 152
Query: 202 APGPPHSAHA--------LPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPG--A 251
G + A + RES T + + P + L VRGR+ P A
Sbjct: 153 RKGSVRALRATSGKRPSNMKRESPTCNL---FPASKSPASSPLTRSTPPVRGRAGPSGRA 209
Query: 252 AEKPKKEI-------PASPSRTKIP-----AEKESHRDVLPDKPAPGAVNVPAAGSHLGQ 299
A P I P++ + ++P A K S + +P A +P +
Sbjct: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
Query: 300 GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSS 354
G+ A+P P+ L +K L + + + PV S P +G +S+
Sbjct: 270 GRGALP-PDSLSTRKGLPRPSTAGHRVRESGHKVPV----SQRLNLPVMGATRSN 319
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 54.7 bits (130), Expect = 3e-07
Identities = 114/531 (21%), Positives = 185/531 (34%), Gaps = 82/531 (15%)
Query: 138 IQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQA 197
+ E KL+ N K+ KK +S E + + GPP + + A LP A A
Sbjct: 63 VPERKLQAN-GPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAA 121
Query: 198 RLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKK 257
+ + + S+ E + + K +A S S + ++P K
Sbjct: 122 KASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPK 181
Query: 258 EIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHL----------GQGKRAIPVP 307
P T + + ++ P + AP N AA S + ++A P
Sbjct: 182 N--QKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239
Query: 308 NKLGLKKTLL-KAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRP 366
K KK ++ KAP + + SS S + K K ++S+P S+ P
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299
Query: 367 LSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEG 426
P +G T PP + + Q E
Sbjct: 300 -------------------PKKSLG-------------------TQPPKKAVEKQQPVES 321
Query: 427 GGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTP 486
+ S + SE + T+++ SK P P K S DS DS +
Sbjct: 322 SEDSSDESDSSSEEEKKPPTKAV-------VSKATTKPPPA---KKAAESSSDSSDSDSS 371
Query: 487 KLSRA-QRPQSCT----SVGRVTVHSTPVRRSSGP-----APQSLLS--ARRVSALPTPA 534
+ A +P T + VT S V+ ++ P Q LL+ A S+ +
Sbjct: 372 EDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESS 431
Query: 535 SRRCSGLPPMTPKTMPRAVG-SPLCVPARRRSSEPRKNSA-MRTEPTRESNRKTDSRLVD 592
S M T P+A + L +PA++ R +S+ + + E KT V
Sbjct: 432 SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK 491
Query: 593 VSPDR---GSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAP 640
P + G+ PS+ A E S+S+ S ++ E EE K G +P
Sbjct: 492 KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEE---EEEKLKGKGSP 539
Score = 54.3 bits (129), Expect = 4e-07
Identities = 101/480 (21%), Positives = 180/480 (37%), Gaps = 39/480 (8%)
Query: 113 ESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSP 172
ESSS +++ ED + Q V++ ++ K+ + S + E + P
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSE----DEPP 180
Query: 173 LLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPG 232
P P + + P A+A A G S+ + S ++ + + P
Sbjct: 181 KNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP- 239
Query: 233 TKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPA 292
K +P+ V + A +K +S S E+E + + +KP P + +VP
Sbjct: 240 -KKTVPKKQVVAKAPVKAATTPTRK---SSSSEDSSSDEEEEQKKPMKNKPGPYS-SVPP 294
Query: 293 AGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSG----PVWSGASSACTSPAV 348
+ + P K K+ +++ +S+ + SS P + S A T P
Sbjct: 295 PSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPP 354
Query: 349 GKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAE 408
K K++E +S ++S + + P+ PAG SS + + +
Sbjct: 355 AK-KAAESSSDSSDSDSSEDDEA-----------PSKPAGTTKNSS------NKPAVTTK 396
Query: 409 QLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTN 468
P+A+P QP GGGQ L + A S SS+ + S + + + TK T
Sbjct: 397 SPAVKPAAAPKQPV---GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKA 453
Query: 469 QFKIP-KFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRV 527
+P K + S DSS+ S + + + V P + + G AP SA++
Sbjct: 454 ALSLPAKQAPQGSRDSSSDSDSSSSEEEE-EKTSKSAVKKKPQKVAGGAAPSKPASAKKG 512
Query: 528 SALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKN--SAMRTEPTRESNRK 585
A + +S K + P A S+ +N +A +E E +K
Sbjct: 513 KAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKK 572
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 54.3 bits (129), Expect = 4e-07
Identities = 141/639 (22%), Positives = 217/639 (33%), Gaps = 99/639 (15%)
Query: 113 ESSSRNQAAQAAKPE---DPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLS 169
E++S + + KPE +P+ E+ ++ K EKEK +S + K + S
Sbjct: 237 EATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK------EKEKTRPRSRSRSKSRSRTRS 290
Query: 170 DSPLLGPPVGEPRLLASS--PALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT 227
SP P R + S P S + R PP PR H S++
Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR-----HRRSRSPV 345
Query: 228 QRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGA 287
+R+ + +AS+ G S ++ + + P RT P K R + P P
Sbjct: 346 RRRRRS------SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT--RRLSPSASPPRR 397
Query: 288 VNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPA 347
+ P+ + R P P + SN RKS S TS
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQ--------------SNRTRKSRVS-----VSPGRTSGK 438
Query: 348 VGKAKSSEFASIPANSSRPL------SNISKSGRMGPAMLRPALPAGPVGASSWQAKRV- 400
V K K +E P+ + +P S K G+M A S Q +R
Sbjct: 439 VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA-------------AADSVQQRRQY 485
Query: 401 -DVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSK 459
++ ++ + S+ +P+ + S S + + R++++ +
Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR 545
Query: 460 TKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQ 519
+ P+P P SP + P +R R T P RRS P
Sbjct: 546 RRRSPSP------PPTRRRRSPSPAPPP---RRRRTPTPPPRRRTPSPPPRRRSPSPRRY 596
Query: 520 SLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPT 579
S RR S P P R S PP P+ SP P RR S P
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPP------PKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650
Query: 580 RESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAA 639
R S + SP R + +R PQ + S S ++ T + + G ++
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSPQP---NKRHSPSPRPRAPQTSSSPPPVRRGASSS 707
Query: 640 PSEALLVDIKLEPL---AVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNT 696
P P+ + TP+ P +P++ V S SR + +
Sbjct: 708 PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP------SPQS-VRRVSSSRSVSG--SPE 758
Query: 697 PDMNKNVAKPSPVVGQLIDLSSPLIQLSPEADKENVDSP 735
P K A PSPV Q SP SP + SP
Sbjct: 759 PAAKKPPAPPSPVQSQ-----SPSTNWSPAVPVKKAKSP 792
Score = 48.5 bits (114), Expect = 2e-05
Identities = 142/664 (21%), Positives = 238/664 (35%), Gaps = 96/664 (14%)
Query: 113 ESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSP 172
+ SSR + ++ P +S+ + S ++ E+++ +SP + T S SP
Sbjct: 159 KESSREKRERSRSPRRRKSRSPSPRRRSSPVRR---ERKRSHSRSP---RHRTKSRSPSP 212
Query: 173 L-----LGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT 227
P + EP + P++ + + + + + P P P+E + +
Sbjct: 213 APEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE--PKEPSPEKNSKKEKE 270
Query: 228 QRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGA 287
+ K + + R RS + +P++ S SR+ P + S R +P+P
Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR-HRSRSRSYSPRRRPSPRR----RPSPRR 325
Query: 288 VNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPA 347
P +R P P + + + S+++L+ SSS +SS SP
Sbjct: 326 RTPP---------RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSS-----SSSRSRSPP 371
Query: 348 VGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAG-------PVGASSWQAKRV 400
K + S P +R LS + R PA P P ++ + RV
Sbjct: 372 ---KKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRV 428
Query: 401 DVS---------ELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRR 451
VS + + PS +P +P+ E + + + + + R RR
Sbjct: 429 SVSPGRTSGKVTKHKGTEKRESPSPAP-KPRKVELSESEEDKGGKMAAADSVQQRRQYRR 487
Query: 452 RDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVR 511
++ S + + +++ + PK S + + + R S + R S R
Sbjct: 488 QNQ--QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR 545
Query: 512 RSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKN 571
R P+P R S P P RR PP R SP P RRRS PR+
Sbjct: 546 RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR------RRTPSP---PPRRRSPSPRRY 596
Query: 572 S---AMRTEPTRESNRKTDS------RLVDVSPD-----RGSPPSR---VPQALNFSPEE 614
S R P+ R+T S R SP SPP + P SP
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656
Query: 615 SDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLI--DF 672
S S+ + RE P + S + P P +S P P +
Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPS--------PRPRAPQTSSSP----PPVRRGA 704
Query: 673 CDTPEAHVAVGSESRPLIDL-MTNTPDMNKNVAKPSPVVGQLIDLSSPLIQLSPEADKEN 731
+P+ + +RP+ + T P K A PSP + + SS + SPE +
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVS-SSRSVSGSPEPAAKK 763
Query: 732 VDSP 735
+P
Sbjct: 764 PPAP 767
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 53.5 bits (127), Expect = 7e-07
Identities = 74/316 (23%), Positives = 110/316 (34%), Gaps = 52/316 (16%)
Query: 114 SSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPL 173
S S A+A+ RS G + + + ++ + SL + + D PL
Sbjct: 463 SPSGGSTAEASDTLSIRSSGQ---LSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPL 519
Query: 174 LGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGT 233
PP E + P P++G AP PP+ A++ PG
Sbjct: 520 GLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSW-----------------VPGL 562
Query: 234 KLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAA 293
PG + +P P SP RT P+ S + P P G PA+
Sbjct: 563 S--------------PGGSRRP----PRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPAS 604
Query: 294 GSHLGQGKRAIPVPNKLGLKKTLLKAPGS--TSNLAR--KSSSGPVWSGASS-ACTSPAV 348
GK P P ++ T L++PG+ +S+L SSS P S S +P
Sbjct: 605 -----PGKAQPPKPERV----TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG 655
Query: 349 GKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAE 408
+ +PA S P S PA+ PA+ GPV + + +
Sbjct: 656 DRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT 715
Query: 409 QLTAPPSASPTQPQTP 424
L P S Q P
Sbjct: 716 PLQESPVISKDQSPPP 731
Score = 43.1 bits (100), Expect = 0.001
Identities = 71/275 (25%), Positives = 100/275 (36%), Gaps = 30/275 (10%)
Query: 150 KEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSA 209
+E+++ + E ++ SP P G P L+ SSPA SS A A + PG P
Sbjct: 778 EEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV-SSPAASSSSATALQIQPPGSPDPP 836
Query: 210 HALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIP 269
A P + A PG LP+ V G S G P +E +P T
Sbjct: 837 PAPP---------APAPASSAPGHVAKLPQKEPV-GCSKGGG---PPREDVGAPLVTPSL 883
Query: 270 AEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARK 329
+ R V APG PA G Q P+ L + + + AP S + A +
Sbjct: 884 LQMVRLRSV----GAPGGAPTPALGPSAPQK----PLRRALSGRASPVPAPSSGLHAAVR 935
Query: 330 SSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGP 389
+ + AS +S +E P P S S G L+ P P
Sbjct: 936 LKACSL--AASEGLSSAQPNGPPEAE----PRPPQSPASTASFIFSKGSRKLQLERPVSP 989
Query: 390 VGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTP 424
+ Q R V+EL + PP A P+ P
Sbjct: 990 ETQADLQ--RNLVAELRSISEQRPPQAPKKSPKAP 1022
Score = 38.9 bits (89), Expect = 0.017
Identities = 66/260 (25%), Positives = 98/260 (37%), Gaps = 28/260 (10%)
Query: 176 PPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKL 235
PP +P ++ +P+ S A+ L PP A P E + A P +
Sbjct: 742 PPTKKPEVVVEAPSA-SETAEEPLQDPNWPPPPPPA-PEEQDLSMADF-------PPPEE 792
Query: 236 LLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPG-AVNVPAAG 294
AS G+ E +S S T + + D P PAP A + P
Sbjct: 793 AFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHV 852
Query: 295 SHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSS 354
+ L Q K + G + + AP T +L + V GA +PA+G
Sbjct: 853 AKLPQ-KEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSV--GAPGGAPTPALG----- 904
Query: 355 EFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSE-LAAEQLTAP 413
P+ +PL + SGR P PA +G A +A + SE L++ Q P
Sbjct: 905 -----PSAPQKPLRR-ALSGRASPV---PAPSSGLHAAVRLKACSLAASEGLSSAQPNGP 955
Query: 414 PSASPTQPQTPEGGGQWLNS 433
P A P PQ+P ++ S
Sbjct: 956 PEAEPRPPQSPASTASFIFS 975
Score = 32.3 bits (72), Expect = 1.6
Identities = 71/319 (22%), Positives = 111/319 (34%), Gaps = 46/319 (14%)
Query: 321 GSTSNLARKSSSGPVWSGASSACTSPAVG-KAKSSEFASIPANSSRPLSNISKSGRMGPA 379
GST + S P S AS++ P G + S A +S LS I SG++
Sbjct: 429 GSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLS-IRSSGQLSGR 487
Query: 380 ML------RP---------------ALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASP 418
+ RP A+P GP+G + +R +L T +
Sbjct: 488 SVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPP-KPERKQQPQLPRPPTTGGSEGAG 546
Query: 419 TQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIG 478
P P W+ S RS R S + + TPT +P +
Sbjct: 547 AAPCPPNPANSWVPGL---SPGGSRRPPRSPERTLSPSSGYSSQSGTPT----LPPKGLA 599
Query: 479 DSPDSSTPKLSRAQRPQSCTSV----GRVTVHSTPV-RRSSGPAPQSLLSARRVSAL--- 530
P S P ++ +P+ TS+ V+ T + SS PAP + ++ L
Sbjct: 600 GPPAS--PGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDR 657
Query: 531 ----PTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKT 586
P P PP P++ P L PA +++ ++ PT ++
Sbjct: 658 FVIPPHPKVPAPFSPPPSKPRS-PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTP 716
Query: 587 DSRLVDVSPDRGSPPSRVP 605
+S D+ PPS P
Sbjct: 717 LQESPVISKDQSPPPSPPP 735
>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
sapiens]
Length = 1798
Score = 52.8 bits (125), Expect = 1e-06
Identities = 97/399 (24%), Positives = 142/399 (35%), Gaps = 59/399 (14%)
Query: 79 PPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFI 138
PP PT+ + SPL+G +A LH+ Q ++ E PRS ++R
Sbjct: 1352 PPPPTASPQRSPSPLSGH-----VAQAFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQ 1406
Query: 139 QESKLKINLFEKEKEMKKS--------PTSLKRETYYLSDSPLLGPPVGEPRLLASSPAL 190
KL L EK++ S + LK+E SPL VG +L+ AL
Sbjct: 1407 SAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPL--EVVGARSVLSGKGAL 1464
Query: 191 PSSGA-QARLTRAPGPPHSAHALPRESCTAHAA------SQAATQRKPG----------- 232
P G Q +RA G A RES A S+ T+ P
Sbjct: 1465 PGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTEEGPENSQGAQELSLA 1524
Query: 233 -----TKLLLPRAASVRGRSIPGAAEKPKKEIPASPSR----TKIPAEKES----HRDVL 279
++ + P+ A G P + P+ P PS T P ES HR +
Sbjct: 1525 PHPEVSQSVAPKGAGESGEEDPFPSRDPRSLGPMVPSLLTGITLGPPRMESPSGPHRRLG 1584
Query: 280 PDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGA 339
+ A + +AG +LGQ P+P + K L T+ S P
Sbjct: 1585 SPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTP----- 1639
Query: 340 SSACTSPA--VGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQA 397
+S+C+ P+ GK + S+ R + + G A L+ P Q
Sbjct: 1640 TSSCSPPSSTSGKLSMWSWKSLIEGPDRASPSRKATMAGGLANLQDLENTTPA-----QP 1694
Query: 398 KRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCA 436
K + E Q + P + + P G W S CA
Sbjct: 1695 KNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLW-ESECA 1732
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 52.4 bits (124), Expect = 2e-06
Identities = 120/536 (22%), Positives = 174/536 (32%), Gaps = 88/536 (16%)
Query: 179 GEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT--QRKPG---- 232
G PR S + S G Q T P S H P TA A + +T R PG
Sbjct: 2197 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 2256
Query: 233 ----------------------------TKLLLPRAASVRGRSIPGAAEKPKKEIPASPS 264
T S RG S EI P
Sbjct: 2257 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 2316
Query: 265 RTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGST- 323
T P E+ +P PA+ + LG G+ + T PGST
Sbjct: 2317 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES----------TTSRSQPGSTH 2366
Query: 324 SNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANS----------SRPLSN---- 369
S ++ S++ P S S+ S + G +++ F P S SRP S
Sbjct: 2367 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTL 2426
Query: 370 -ISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSA-------SPTQP 421
S G A P P + + ++L E T P S+ SP +
Sbjct: 2427 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2486
Query: 422 QTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQ-----FKIPKFS 476
T G+ ++ S SS T L+ K+ T S
Sbjct: 2487 TTSGLVGE--STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 2544
Query: 477 IGDSPDSSTPKLSRAQR-----PQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALP 531
G S +SST P S T+ G ++ HST S G +LL A ++ P
Sbjct: 2545 SGVSEESSTSHSQPGSTHTTAFPDSTTTPG-LSRHSTTSHSSPGSTDTTLLPASTTTSGP 2603
Query: 532 TPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLV 591
+ S P T + + GS + + S+ +S T T + T S +V
Sbjct: 2604 SQESTTSHSSPGSTDTAL--SPGSTTALSFGQEST-TFHSSPGSTHTTLFPDSTTSSGIV 2660
Query: 592 DVS----PDRGSPPSRVPQALNFSPE-ESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ S GSP + + A + SP + +ST ++ + P AP E
Sbjct: 2661 EASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVE 2716
Score = 48.9 bits (115), Expect = 2e-05
Identities = 117/516 (22%), Positives = 172/516 (33%), Gaps = 76/516 (14%)
Query: 179 GEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT--QRKPG---- 232
G PR S + S G Q T P S H P TA A + +T R PG
Sbjct: 1114 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 1173
Query: 233 ----------------------------TKLLLPRAASVRGRSIPGAAEKPKKEIPASPS 264
T S RG S EI P
Sbjct: 1174 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 1233
Query: 265 RTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS 324
T P E+ +P PA+ + LG G+ + ++ G + + +P ST+
Sbjct: 1234 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV-SPASTT 1292
Query: 325 NLARKSSSGPVWSGASSA--------CTSPAVGKAKSSEFASIPANSSRPLSNISKSGRM 376
S V+S + + T+ +V + + F S PA++ L S
Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT-EDSTTS 1351
Query: 377 GPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCA 436
G A P P + + ++L E T P S+ T + S A
Sbjct: 1352 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL----------SPA 1401
Query: 437 WSESSQLNKTRSIRRRDSCLNSKTKVMP----TPTNQFKIPKFSIGDSPDSSTPKLSRAQ 492
S +S L S R S +++T +P TP+ K F SP S LS A
Sbjct: 1402 RSTTSGL-VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY--TSPRSPDATLSPAT 1458
Query: 493 RPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTP-KTMPR 551
S S T HS P + P S ++ T S + S ++P T
Sbjct: 1459 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS 1518
Query: 552 AVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVS-PDRGSPPS----RVPQ 606
++G + S +S TE T + S LV+ S P S S P
Sbjct: 1519 SLG---------QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 1569
Query: 607 ALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ + + +ST +S + + PG AAP E
Sbjct: 1570 SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVE 1605
Score = 47.4 bits (111), Expect = 5e-05
Identities = 122/553 (22%), Positives = 181/553 (32%), Gaps = 87/553 (15%)
Query: 179 GEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT--QRKPG---- 232
G PR S + S G Q T P S H P TA A + +T R PG
Sbjct: 3754 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 3813
Query: 233 ----------------------------TKLLLPRAASVRGRSIPGAAEKPKKEIPASPS 264
T S RG S EI P
Sbjct: 3814 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 3873
Query: 265 RTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS 324
T P E+ +P PA+ + LG G+ + ++ G + + +P ST+
Sbjct: 3874 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV-SPASTT 3932
Query: 325 NLARKSSSGPVWSGASSA--------CTSPAVGKAKSSEFASIPANSSRPLSNISKSGRM 376
S V+S + + T+ +V + + + F S PA++ L S
Sbjct: 3933 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFT-EDSTTS 3991
Query: 377 GPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCA 436
G A P P + + ++L E T P S+ T + S A
Sbjct: 3992 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL----------SPA 4041
Query: 437 WSESSQLNKTRSIRRRDSCLNSKTKVMP----TPTNQFKIPKFSIGDSPDSSTPKLSRAQ 492
S +S L S R S +++T +P TP+ K F SP S LS A
Sbjct: 4042 RSTTSGL-VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY--TSPRSPDATLSPAT 4098
Query: 493 RPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTP-KTMPR 551
S S T HS P + P S ++ T S + S ++P T
Sbjct: 4099 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTAS 4158
Query: 552 AVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFS 611
++G + S +S TE T + S LV+ S S + L +
Sbjct: 4159 SLG---------QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL--T 4207
Query: 612 PEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLID 671
P S ST + +T + D PS + P+ V+ S+P
Sbjct: 4208 PASSTSTGLQEESTTF--QSWPSSSDTTPSPPSTTAV---PVEVSTTYHSRP-------- 4254
Query: 672 FCDTPEAHVAVGS 684
TP H + S
Sbjct: 4255 -SSTPTTHFSASS 4266
Score = 47.0 bits (110), Expect = 6e-05
Identities = 119/515 (23%), Positives = 169/515 (32%), Gaps = 74/515 (14%)
Query: 179 GEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT--QRKPG---- 232
G PR S + S G Q T P S H P TA A + +T R PG
Sbjct: 2671 GSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 2730
Query: 233 ----------------------------TKLLLPRAASVRGRSIPGAAEKPKKEIPASPS 264
T S RG S EI P
Sbjct: 2731 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 2790
Query: 265 RTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS 324
T P E+ +P PA+ + LG G+ + ++ G + + +P ST+
Sbjct: 2791 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV-SPASTT 2849
Query: 325 NLARKSSSGPVWSGASSA--------CTSPAVGKAKSSEFASIPANSSRPLSNISKSGRM 376
S V+S + + T+ +V + + F S PA++ L S
Sbjct: 2850 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFT-EDSTTS 2908
Query: 377 GPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCA 436
G A P P + + ++L E T P S+ G S A
Sbjct: 2909 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS----------GSTGTTLSPA 2958
Query: 437 WSESSQLNKTRSIRRRDSCLNSKTKVMP----TPTNQFKIPKFSIGDSPDSSTPKLSRAQ 492
S +S L S R S +++T +P TP+ K F SP S LS A
Sbjct: 2959 RSTTSGL-VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY--TSPRSPDATLSPAT 3015
Query: 493 RPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRA 552
S S T HS P + P S ++ +S PT AS G T
Sbjct: 3016 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS-GLSQEPT-ASHSSQGSTEATLSPGSTT 3073
Query: 553 VGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVS-PDRGSPPS----RVPQA 607
S + S +S TE T + S LV+ S P S S P +
Sbjct: 3074 ASS------LGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPAS 3127
Query: 608 LNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ + +ST +S + + PG AAP E
Sbjct: 3128 STSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVE 3162
Score = 41.6 bits (96), Expect = 0.003
Identities = 115/517 (22%), Positives = 181/517 (35%), Gaps = 83/517 (16%)
Query: 155 KKSPTSLKRETYYLSDSP-LLGPPVGEPRLLASSPA------LPSSGAQARLTRAPGPPH 207
++S TS T+ +S +P V EP SSP P S + + H
Sbjct: 3495 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 3554
Query: 208 SAH------ALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKK--EI 259
S+ LP S T+ ++ T P + + A + PG +EK
Sbjct: 3555 SSQDATGTIVLPARSTTSVLLGESTTS--PISSGSMETTALPGSTTTPGLSEKSTTFHSS 3612
Query: 260 PASPSRTKIPAEKES-----------------HRDVLPDKPAPGAVNVPAAGSHLGQGKR 302
P SP+ T PA S H PD ++ + SH G
Sbjct: 3613 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 3672
Query: 303 AIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKA-----KSSEFA 357
TLL A +TS +++S++ SG++ SP A +S+ F
Sbjct: 3673 ----------DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFH 3722
Query: 358 SIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSAS 417
S P ++ L S + +G V AS+ RV S + +P S++
Sbjct: 3723 SSPGSTHTTLFPDSTTS------------SGIVEAST----RVHSSTGSPRTTLSPASST 3766
Query: 418 PTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSI 477
Q Q +S + S T + + S TPT F +
Sbjct: 3767 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS---TPTTHFPASSTTS 3823
Query: 478 GDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRR 537
G S S+ + + S T+ + HST R G + S +S P S
Sbjct: 3824 GHSEKST---IFHSSPDASGTTPS--SAHSTTSGR--GESTTSRISPGSTEITTLPGSTT 3876
Query: 538 CSGL--PPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSP 595
GL T + PR+ + L + +++ R++P S T S +P
Sbjct: 3877 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP--GSTHSTVSPASTTTP 3934
Query: 596 DRGSPPSRVPQALNFSPEESDST-FSKSTATEVAREE 631
+ V + SP +++T F +ST T V REE
Sbjct: 3935 GLSEESTTV---YSSSPGSTETTVFPRSTTTSVRREE 3968
Score = 39.7 bits (91), Expect = 0.010
Identities = 102/480 (21%), Positives = 160/480 (33%), Gaps = 67/480 (13%)
Query: 161 LKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP----RES 216
L+ E+ P P ++P S+ +R + P SA + ES
Sbjct: 3133 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 3192
Query: 217 CTAHAASQAATQRKPGTKLLLPRAAS--VRGRSIPGAAEKPKKEIPASPSRTKIPAEKES 274
T H++ A GT L R+A+ + G E A P T E
Sbjct: 3193 TTVHSSPGAT-----GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 3247
Query: 275 HRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS--NLARKSSS 332
+P PA+ + G + + ++ G T PGST+ ++++S++
Sbjct: 3248 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTA-FPGSTTMPGVSQESTA 3306
Query: 333 GPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPAL-PAGPVG 391
G++ SP S A+S P S SG P L P
Sbjct: 3307 SHSSPGSTDTTLSPG----------STTASSLGPESTTFHSG---PGSTETTLLPDNTTA 3353
Query: 392 ASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRR 451
+ +A S + T P+ S T+ W NS +++ T +
Sbjct: 3354 SGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSK----DTTPAPPTTTSAF 3409
Query: 452 RDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVR 511
+ S TPT F ++G S +S+T VHS+PV
Sbjct: 3410 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT-------------------VHSSPVA 3450
Query: 512 RSSGPAPQSLLSARRVSALPT----PASRRCSGLPPMTPKTMPRAVGSPLCVPARRR--S 565
++ P+P ++ V T P S + P + T R S + S
Sbjct: 3451 TATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE-SDTTSGRGEESTTSHSSTTHTIS 3509
Query: 566 SEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTAT 625
S P SA+ EPT + S PD + R EES ++ S AT
Sbjct: 3510 SAPSTTSALVEEPT-SYHSSPGSTATTHFPDSSTTSGR--------SEESTASHSSQDAT 3560
Score = 39.3 bits (90), Expect = 0.013
Identities = 113/499 (22%), Positives = 172/499 (34%), Gaps = 97/499 (19%)
Query: 190 LPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIP 249
LP + L A P HS+ + T +++ Q + T P ++
Sbjct: 4179 LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTT----- 4233
Query: 250 GAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNK 309
P+ PS T +P E + P + A+ + LG+ + + V +
Sbjct: 4234 ----------PSPPSTTAVPVEVSTTYHSRPSSTP--TTHFSASSTTLGRSEESTTVHSS 4281
Query: 310 LGLKKT-LLKAPGSTSNLARKSSSGPVWSGASSACTSP-----AVGKAKSSEFASIPANS 363
G T L +TS L + ++ P+ SG++ P A KS+ F S P +
Sbjct: 4282 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 4341
Query: 364 SRPLSNISKSG------------RMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLT 411
LS S + R G +M A P+ Q S + T
Sbjct: 4342 DTTLSPASTTSSGVSEESTTSHSRPG-SMHTTAFPSSTTMPGVSQESTASHSSPGSTDTT 4400
Query: 412 APPSASPTQPQTPEGGGQWLNSSCAWSESSQL--NKTRS--------------------- 448
P ++ PE +SS +E++ L N T S
Sbjct: 4401 LSPGSTTASSLGPES--TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 4458
Query: 449 -----IRRRDSCL-----NSK--TKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQS 496
R+ +S NSK T PT T+ F + SP SSTP + S
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSP-SSTPTTHFSA---S 4514
Query: 497 CTSVGR----VTVHSTPVRRSSGPAPQSLLSARRVSALPT----PASRRCSGLPPMTPKT 548
T++GR TVHS+PV ++ P+P ++ V T P S + P + T
Sbjct: 4515 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE-SNTT 4573
Query: 549 MPRAVGSPLCVPARRR--SSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQ 606
R S + SS P SA+ EPT + S PD + R
Sbjct: 4574 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGSTATTHFPDSSTTSGR--- 4629
Query: 607 ALNFSPEESDSTFSKSTAT 625
EES ++ S AT
Sbjct: 4630 -----SEESTASHSSQDAT 4643
Score = 38.9 bits (89), Expect = 0.017
Identities = 96/458 (20%), Positives = 161/458 (35%), Gaps = 44/458 (9%)
Query: 155 KKSPTSLKRETYYLSDSP-LLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP 213
++S TS T+ +S +P V EP SSP ++ P S +
Sbjct: 4578 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT--------THFPDSSTTSGR 4629
Query: 214 RESCTAHAASQAATQRKPGTKLLLPRAAS--VRGRSIPGAAEKPKKEIPASPSRTKIPAE 271
E TA +SQ AT GT +L R+ + + G S E A P T P
Sbjct: 4630 SEESTASHSSQDAT----GTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 4685
Query: 272 KESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNK-LGLKKTLLKAPGSTSNLARKS 330
E + + A+ + LG+ + + V + + T A +TS L +S
Sbjct: 4686 SEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 4745
Query: 331 SSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRP-ALPAGP 389
++ G++ P A S ++SS + S + P + + P
Sbjct: 4746 TAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP 4805
Query: 390 VGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTP-----EGGGQWLNSSCAWSESSQLN 444
++ + +E+ TA S+ T TP G+ S+ + +
Sbjct: 4806 GSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSME 4865
Query: 445 KTRSIRRRDSCLNSKTKVM------PTPT-NQFKIPKFSIGDSPDSSTPKLSRAQR---P 494
T + L++K+ ++ P T + + SI P S + P
Sbjct: 4866 TTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFP 4925
Query: 495 QSCTSVG----RVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMP 550
S T+ G T HS P + +P S+ ++ TP S+ S L ++P
Sbjct: 4926 ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSP---- 4981
Query: 551 RAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDS 588
+ VP S +S TE T S+ T S
Sbjct: 4982 ----ASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS 5015
Score = 38.5 bits (88), Expect = 0.023
Identities = 100/481 (20%), Positives = 158/481 (32%), Gaps = 75/481 (15%)
Query: 161 LKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP----RES 216
L+ E+ P P ++P S+ +R + P SA + ES
Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635
Query: 217 CTAHAASQAATQRKPGTKLLLPRAAS--VRGRSIPGAAEKPKKEIPASPSRTKIPAEKES 274
T H++ A GT L R+A+ + G E A P T E
Sbjct: 1636 TTVHSSPGAT-----GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 1690
Query: 275 HRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS-------NLA 327
+P PA+ + G + + ++ G T PGST+ + A
Sbjct: 1691 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTA-FPGSTTMPGVSQESTA 1749
Query: 328 RKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPA 387
SS G + S T+ + +S+ F S P ++ L LP
Sbjct: 1750 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL-----------------LPD 1792
Query: 388 GPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTR 447
+ +A S + T P+ S T+ W +S ++ T
Sbjct: 1793 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSK----DTMPAPPTT 1848
Query: 448 SIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHS 507
+ + S TPT F ++G S +S+T VHS
Sbjct: 1849 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT-------------------VHS 1889
Query: 508 TPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSE 567
+PV ++ P+P AR ++ S P T + + P A RS E
Sbjct: 1890 SPVATATTPSP-----ARSTTSGLVEESTAYHSSPGST-----QTMHFPESSTASGRSEE 1939
Query: 568 PRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPP-----SRVPQALNFSPEESDSTFSKS 622
R + + T T S T S LV+ S P + P + S +ST S S
Sbjct: 1940 SRTSHSSTTH-TISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 1998
Query: 623 T 623
+
Sbjct: 1999 S 1999
Score = 34.7 bits (78), Expect = 0.33
Identities = 111/506 (21%), Positives = 181/506 (35%), Gaps = 61/506 (12%)
Query: 155 KKSPTSLKRETYYLSDSP-LLGPPVGEPRLLASSPA------LPSSGAQARLTRAPGPPH 207
++S TS T+ +S +P V EP SSP P S + + H
Sbjct: 855 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 914
Query: 208 SAH------ALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKK--EI 259
S+ LP S T+ ++ T P + + A + PG +E+
Sbjct: 915 SSQDATGTIVLPARSTTSVLLGESTTS--PISSGSMETTALPGSTTTPGLSERSTTFHSS 972
Query: 260 PASPSRTKIPAEKESH---RDVLPDKPAPGAVNV---PAAGSHLGQGKRAIPVPNKLG-L 312
P SP+ T PA S + + PG+ + P + + G + + + G
Sbjct: 973 PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 1032
Query: 313 KKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKA-----KSSEFASIPANSSRPL 367
TLL A +TS +++S++ SG++ SP A +S+ F S P ++ L
Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 1092
Query: 368 SNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGG 427
S + +G V AS+ RV S + +P S++ Q
Sbjct: 1093 FPDSTTS------------SGIVEAST----RVHSSTGSPRTTLSPASSTSPGLQGESTA 1136
Query: 428 GQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPK 487
Q +S + S T + + S TPT F + G S S+
Sbjct: 1137 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS---TPTTHFPASSTTSGHSEKST--- 1190
Query: 488 LSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGL--PPMT 545
+ + S T+ + HST R G + S +S P S GL T
Sbjct: 1191 IFHSSPDASGTTPS--SAHSTTSGR--GESTTSRISPGSTEITTLPGSTTTPGLSEASTT 1246
Query: 546 PKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVP 605
+ PR+ + L + +++ R++P S T S +P + V
Sbjct: 1247 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP--GSTHSTVSPASTTTPGLSEESTTVY 1304
Query: 606 QALNFSPEESDSTFSKSTATEVAREE 631
+ S E + F ST T V EE
Sbjct: 1305 SSSRGSTE--TTVFPHSTTTSVHGEE 1328
Score = 34.3 bits (77), Expect = 0.43
Identities = 88/428 (20%), Positives = 142/428 (33%), Gaps = 85/428 (19%)
Query: 203 PGPPHSAHALPRESCTAHAA-SQAATQRKPGTKLLLPRAA-SVRGRSIPGAAEKPKKEIP 260
P PP + A S T+H + S T + L R+ S S P A
Sbjct: 4483 PAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP---- 4538
Query: 261 ASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAP 320
SP+R+ E + ++ P + + G+G+ + + T+ AP
Sbjct: 4539 -SPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEES--TTSHSSTTHTISSAP 4595
Query: 321 GSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAM 380
+TS L + +S G+++ P S ++SS+ +
Sbjct: 4596 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI--------- 4646
Query: 381 LRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSES 440
LPA R S L E T+P S+ + G
Sbjct: 4647 ---VLPA-----------RSTTSVLLGESTTSPISSGSMETTALPGS------------- 4679
Query: 441 SQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSV 500
T + + + +S TPT F ++G S +S+T
Sbjct: 4680 ---TTTPGLSEKSTTFHSSPS--STPTTHFSASSTTLGRSEESTT--------------- 4719
Query: 501 GRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVP 560
VHS+PV ++ P+P AR ++ S P T + + P
Sbjct: 4720 ----VHSSPVATATTPSP-----ARSTTSGLVEESTAYHSSPGST-----QTMHFPESST 4765
Query: 561 ARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRV-----PQALNFSPEES 615
A RS E R + + T T S T S LV+ S P + P++ S
Sbjct: 4766 ASGRSEESRTSHSSTTH-TISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSE 4824
Query: 616 DSTFSKST 623
+ST S S+
Sbjct: 4825 ESTASHSS 4832
Score = 31.6 bits (70), Expect = 2.8
Identities = 93/473 (19%), Positives = 161/473 (34%), Gaps = 52/473 (10%)
Query: 185 ASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLL--PRAAS 242
ASS L S + +P + R + + H A R PG+ + P +++
Sbjct: 462 ASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST 521
Query: 243 VRGRSIPGAA--EKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQG 300
G S A ++PS T A H + + + +G +
Sbjct: 522 TSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRS-EES 580
Query: 301 KRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIP 360
K + P+ + T+L A + S L S+ P+ SG S E ++P
Sbjct: 581 KASHSSPDAMAT--TVLPAGSTPSVLVGDSTPSPISSG--------------SMETTALP 624
Query: 361 ANSSRP-LSNISKSGRMGPAMLRPA-LPAGPVGASSWQAKRVDVSELAAEQLTAPP---- 414
++++P LS S + P LPA + + S + TA P
Sbjct: 625 GSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTT 684
Query: 415 ----SASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQF 470
S T + G S + + SS + + R +++T ++P T
Sbjct: 685 MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPG--STETTLLPDNTTAS 742
Query: 471 KIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSAL 530
+ + S+ + +P + + + T HS P + + PAP + SA
Sbjct: 743 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAF----- 797
Query: 531 PTPASRRCSGLPPMTPKT--MPRAVGSPLCVPARRRSSEPRKNSAM----------RTEP 578
S G P P T R+ S L + S P M R E
Sbjct: 798 -VEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856
Query: 579 TRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREE 631
+ S+ T + + +P S P + + SP + +T ++T R E
Sbjct: 857 STTSHSST-THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 908
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 52.4 bits (124), Expect = 2e-06
Identities = 126/597 (21%), Positives = 199/597 (33%), Gaps = 121/597 (20%)
Query: 59 GHKERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRN 118
G +E E +P E+ P E A SP+ E ++ A E
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKE---AKSPVKEEA------KSPAEAKSPEKEEAK 539
Query: 119 QAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPV 178
A+ PE +S E E+K EKE KSP +K S P
Sbjct: 540 SPAEVKSPEKAKSPAKE----EAKSPPEAKSPEKEEAKSPAEVK------SPEKAKSPAK 589
Query: 179 GEPRLLASSPALPSSGAQAR--LTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLL 236
E A SPA S +A+ + P A + +E + A ++ + K TK
Sbjct: 590 EE----AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK-- 643
Query: 237 LPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSH 296
P A+ P+KE SP + K P + E+ +P P
Sbjct: 644 -------EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA--------KSPEKAKSPVKAEA 688
Query: 297 LGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEF 356
K PV K K+P + + PV A SP K+ E
Sbjct: 689 KSPEKAKSPV-------KEEAKSP--------EKAKSPVKEEAK----SPEKAKSPVKEE 729
Query: 357 ASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSA 416
A P + P+ +KS P P A + K + A E+ +P
Sbjct: 730 AKTPEKAKSPVKEEAKS---------PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780
Query: 417 SPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFS 476
P + ++P E K +S + D+ K +IPK
Sbjct: 781 FPEKAKSP-----------VKEEVKSPEKAKSPLKEDAKAPEK-----------EIPKKE 818
Query: 477 IGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASR 536
SP + ++PQ V V P + AP + + + + A +
Sbjct: 819 EVKSP------VKEEEKPQ------EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866
Query: 537 RCSGLPPMTPKTMPRAVGSP--LCVPARRRSSE-------PRKNSAMRTEPTRESNRKTD 587
+ + P + K P AV P V A++ +E P K + + E ++ K
Sbjct: 867 KEAPKPKVEEKKEP-AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK 925
Query: 588 SRLVDVSPD--RGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ + PD + PS+ + +PE+ D+ K+ + E KP +A E
Sbjct: 926 TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA-----KKPEEKPKTEAKAKE 977
Score = 39.7 bits (91), Expect = 0.010
Identities = 81/411 (19%), Positives = 142/411 (34%), Gaps = 35/411 (8%)
Query: 252 AEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLG 311
AE ++E + P+ EKE+ V + +P P + P K
Sbjct: 494 AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553
Query: 312 LKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNIS 371
K+ K+P + ++ + P + SPA +AKS A P + P+ +
Sbjct: 554 AKEEA-KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 372 KSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELA----AEQLTAPPSASPTQPQTPEGG 427
KS PA PV + V E A E+ +P A P+ E
Sbjct: 613 KS---------PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK--SPEKEEAK 661
Query: 428 GQWLNSSCAWSESSQLNKTRSIRRRDS----CLNSKTKVMPTPTNQFKIPKFSIGDSPD- 482
S +E+ K +S + ++ S K + K P SP+
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 483 SSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPA-------PQSLLSARRVSALPTPAS 535
+ +P A+ P+ S + S +S A P++ A+ + P
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 536 RRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSP 595
+ P P SPL A+ E K +++ P +E + + ++ + P
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS-PVKEEEKPQEVKVKE--P 838
Query: 596 DRGSPPSRVPQALNFSPEESDSTFSKSTATEVAR---EEAKPGGDAAPSEA 643
+ + + P A + E+ DS ++ E + EE K P E+
Sbjct: 839 PKKAEEEKAP-ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 52.0 bits (123), Expect = 2e-06
Identities = 132/573 (23%), Positives = 195/573 (34%), Gaps = 116/573 (20%)
Query: 75 VPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGV 134
+P PPL TS SP A SPL+ + + LA H P+ P S +
Sbjct: 463 LPASPPLQTSLSP-AVSPLSSPLTIHPLQALSSLASH-------------SPQAPLSSLI 508
Query: 135 ERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSG 194
+ E + +P SL+ L+ PL P P P L ++
Sbjct: 509 ------------MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP------PPLQTAS 550
Query: 195 AQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEK 254
A PP A C A T P T + A+ ++ P A
Sbjct: 551 APLTTPHLETPPCPA------PCPLQAPPSPLTTPPPETPSSI---ATPPPQAPPALASP 601
Query: 255 PKKEIPASP-SRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIP-VPNKLGL 312
P + +P+ P S P + LP AP + P A L P PN L +
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS---PPASPPLSPLATPSPQAPNALAV 658
Query: 313 KKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISK 372
LL+AP S S PV + S + P + S+ P S
Sbjct: 659 H--LLQAPFSPP------PSPPVQAPFSPPASPPV-------------SPSATPPSQAPP 697
Query: 373 SGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLN 432
S P + P+ PA P + S LAA L PPS + P +P
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA------ 751
Query: 433 SSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQ 492
+V P P + SP +S P A+
Sbjct: 752 ------------------------TPPPRVPPL----LAAPPLQVPPSPPASLPMSPLAK 783
Query: 493 -RPQSCTSVGRVTVHSTPVRRSS--GPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTM 549
PQ+ ++ + + P +S G AP S ++ +S L TP + PP+ +
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ----APPVLAAPL 839
Query: 550 PRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALN 609
+ SP PA PR+ + + R T + ++P PPSR P +
Sbjct: 840 LQVPPSP---PASPTLQAPRRPPTPGPDTSVSGPRLT----LALAPGPPPPPSRSPSSTL 892
Query: 610 FSPE-ESDSTFSKSTATEVAREEAKPGGDAAPS 641
P+ S+ + ST E+ ++ P G AA S
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Score = 48.9 bits (115), Expect = 2e-05
Identities = 126/537 (23%), Positives = 183/537 (34%), Gaps = 74/537 (13%)
Query: 192 SSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGA 251
S+GA+ R T P P + A+ R S R GT++ LPR A P A
Sbjct: 157 SAGAR-RDTSGPTPGTPSPAMARRS------------RAAGTEVGLPRPA-------PSA 196
Query: 252 AEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLG 311
+P E P ++ A + S + P+P A P+AG L + P L
Sbjct: 197 RPRPPTE---GPRKSVSSASEHSTTE-----PSPAARRRPSAGGGLQR-----PASRSLS 243
Query: 312 LKKTLLKAPGSTSNLARKSSSGPVWSGASS-----ACTSPAVGKAKSSEFASIPANSSRP 366
T L +P + AR + P A P V + ++ SS P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 367 LSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVS-ELAAEQLTAPPSAS--PTQPQT 423
L+ S SG + P A P+ A+ + + LA +APPS P+ P T
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 424 PEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPD- 482
P ++ L I+ S + + P+P + + SP
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423
Query: 483 ---SSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCS 539
S +S Q S TS R STP AP SL ++ + +PA S
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPA--STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481
Query: 540 GLPPMTP--------KTMPRAVGSPLCVPARRRSSEPRKNS------AMRTEPTRESNRK 585
+ P P+A S L +P S S ++ T P
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541
Query: 586 TDSRLVDVS-----PDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAP 640
L S P +PP P L P + ++ ++ P A+P
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
Query: 641 SEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTP 697
L L PLA P A P + LP + +P A S PL L T +P
Sbjct: 602 PLQGLPSPPLSPLATPPPQA-PPXLALPPLQAPPSPPA-------SPPLSPLATPSP 650
Score = 38.5 bits (88), Expect = 0.023
Identities = 121/555 (21%), Positives = 182/555 (32%), Gaps = 149/555 (26%)
Query: 169 SDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGP---PHSAHALPRESCTAHAASQA 225
+ +P PP+ P L +SP L +S L+ A P P + H L S A + QA
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTS-----LSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 226 ATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAP 285
P + L++P + + P P S T P E LP P
Sbjct: 503 -----PLSSLIMPPLETQSSLAPPSLQTPPA-------SLTTPPLEN------LPSLAPP 544
Query: 286 G--AVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSAC 343
+ P HL P P + P + S++A P
Sbjct: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP--------- 595
Query: 344 TSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVS 403
PA +S PL + P+ P P+ QA
Sbjct: 596 ----------------PALASPPLQGL------------PSPPLSPLATPPPQAP----P 623
Query: 404 ELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVM 463
LA L APPS + P +P + S Q ++ + +
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLA-----------TPSPQAPNALAVHLLQAPFS------ 666
Query: 464 PTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTS----VGRVTVHSTPVRRSSGPAPQ 519
P P+ + P FS SP S +Q P S + V S P+ S+ P PQ
Sbjct: 667 PPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 520 SL--LSARRVSALPTPASRRCSGLPPMTP------KTMPRAVGSPLCVPARRRSSEPRKN 571
+ L+A + P+P + PPM+P + P PL VP +S P
Sbjct: 726 APPPLAAPPLQVPPSPPAS-----PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 572 SAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREE 631
A +P ++ + + P SPP+ P FSP S
Sbjct: 781 LA---KPPPQAPPALATPPLQALP---SPPASFPGQAPFSPSAS---------------- 818
Query: 632 AKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLID 691
+ + PLA TP + P++ PL+ +P A + + RP
Sbjct: 819 ----------------LPMSPLA-TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--- 858
Query: 692 LMTNTPDMNKNVAKP 706
TP + +V+ P
Sbjct: 859 ---PTPGPDTSVSGP 870
Score = 35.8 bits (81), Expect = 0.15
Identities = 103/457 (22%), Positives = 160/457 (35%), Gaps = 93/457 (20%)
Query: 280 PDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSS--SGPVWS 337
P P P PAA R + +G K +A G +S+ +GP S
Sbjct: 30 PGSPRPPPPVTPAA-------LRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS 82
Query: 338 GASS----ACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGAS 393
+S A PA G+ + + PA ++ P +S GR RP GP+G
Sbjct: 83 AGTSSRNPASRPPASGRGERAP----PAKNTSP-GPVSSPGRAS-GTTRP----GPLGQK 132
Query: 394 SWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRD 453
+ ++AE+ A A+ ++ G RRD
Sbjct: 133 GLR--------ISAEETVARGKATEAPKRSALSAGA---------------------RRD 163
Query: 454 SCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRS 513
+ + T P+P + + S + P+ + + RP+ T R +V S +
Sbjct: 164 T--SGPTPGTPSPA----MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 514 SGPAPQSLLSARRVSALPTPASR--RCSGLPPMTP-KTMPRAVGSPLCVPARRRSSEPRK 570
+ P+P + L PASR S P +P ++ P A G+P PA +P+
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR-APAHPSQPKPKG 276
Query: 571 NSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVARE 630
A+R P + +PP R A P S + S + AR
Sbjct: 277 LQALR-------------------PPQVTPP-RKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 631 EAKPGGDAAPSEALLVDIK--LEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRP 688
P A P A L PL + P + S P P + +P A S++ P
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP----PSLQTLPSPPA--TPPSQAPP 370
Query: 689 LIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPLIQLSP 725
MT P + P + L+SP +Q P
Sbjct: 371 ---SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
Score = 30.8 bits (68), Expect = 4.7
Identities = 74/288 (25%), Positives = 99/288 (34%), Gaps = 48/288 (16%)
Query: 168 LSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGP-PHSAHALPRESCTAHAASQAA 226
L+ P PPV LL P+ P+S R P P P ++ + PR +
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883
Query: 227 TQRKPGTKLLLP------RAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKE---SHRD 277
R P + L P +A+ + G P+ ASP P + E H
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP-----PPDAELAACHPA 938
Query: 278 VLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLAR-KSSSGPVW 336
PAP A G+ L P P G PGS L + GP
Sbjct: 939 AWSRGPAPPLAFRGAPGAPL-------PWPPATG--------PGSADGLCTIYETEGPES 983
Query: 337 S----GASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGA 392
+ GA SP K++ A A+S P K R+G LP G + A
Sbjct: 984 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP-----KQARLG------ELPLGALQA 1032
Query: 393 SSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSES 440
S Q LAA + A S P EGGG + A S++
Sbjct: 1033 SVVQHLLSRTLLLAAAEGAA--GGSGGGPGGAEGGGVTGGARAALSDA 1078
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 50.1 bits (118), Expect = 8e-06
Identities = 132/583 (22%), Positives = 197/583 (33%), Gaps = 80/583 (13%)
Query: 74 PVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQG 133
P P PP+PT+ P A + K AH L + S S + + P + G
Sbjct: 849 PGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLV---PAAAG 905
Query: 134 VERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSS 193
+Q ++ + + ++ R + GPP P+ SS AL
Sbjct: 906 PYATVQR---RVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPK--RSSSAL--- 957
Query: 194 GAQARLTRAPGP---PHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPG 250
A A L P P P R C AS A G+ + A++ S G
Sbjct: 958 -ASANLADEPVPDAEPEDGLLGVRAQC--RRASDLAGSVDTGSAGSVKSIAAMLELSSIG 1014
Query: 251 AAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAV-NVPAAGSHLGQGKRAIPVPNK 309
+ + P E H P P PG V V A+ H K AI
Sbjct: 1015 GGGRAARRPP------------EGHPTPRPASPEPGRVATVLASVKH----KEAI----- 1053
Query: 310 LGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLS- 368
PG R++ SGPV ++A P A F RP
Sbjct: 1054 ---------GPGGEVVNRRRTLSGPVTGLLATARRGPG-ESADPGPFVEDGTGRQRPRGP 1103
Query: 369 NISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGG 428
+ ++G GP P V AS+ +R+ + E + + S T + P+
Sbjct: 1104 SKGEAGVEGP-------PLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKE 1156
Query: 429 QWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKL 488
+ S N T ++RRR + + +P P + P + P P+
Sbjct: 1157 REAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPE- 1215
Query: 489 SRAQRPQSCTSVGRVTVHSTPVRRSSG-PAPQSLLSARRVSALPTPAS---RRCSGLPPM 544
A++P V V + PV + G P P S + LP P S +R G PP
Sbjct: 1216 GEARKPAK-PPVSPKPVLTQPVPKLQGSPTPTS-----KKVPLPGPGSPEVKRAHGTPPP 1269
Query: 545 T------PKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRG 598
P T P+ V + +P+ P + A R P + + SP
Sbjct: 1270 VSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPA-RQPPAALAKPPGTPPSLGASP--A 1326
Query: 599 SPPSRVPQALNF---SPEESDSTFSKSTATEVAREEAKPGGDA 638
PPS AL+ P + + + + A E A PG A
Sbjct: 1327 KPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSA 1369
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 50.1 bits (118), Expect = 8e-06
Identities = 92/415 (22%), Positives = 151/415 (36%), Gaps = 44/415 (10%)
Query: 79 PPLPTSESPFAWSPLAGEKFVEVYKEAHLLA---LHIESSSRNQAAQAAKPEDPRSQGVE 135
PP P+ P S A E F E+ A LA L ++R + +A E+ ++G
Sbjct: 2393 PPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPR 2452
Query: 136 RFIQESKLKINLFEKEKEMKKSPTSLK-RETYYLSDSPLLGPPVGEPRLLASSPALPSSG 194
R +E++L + L + E SP S K +E L + P G EP+ L S + P +
Sbjct: 2453 RPGEEAELLVKL---DHEGVTSPKSKKAKEALLLREDPGAGG-WQEPKSLLSLGSYPPAA 2508
Query: 195 AQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEK 254
+ +AP P + L +E + + P A S ++
Sbjct: 2509 GSSE-PKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS 2567
Query: 255 PKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKK 314
+S S ++ E+E DK G + A
Sbjct: 2568 SSSSSSSSSSGSETEGEEEG------DKNGDGGCGTGGRNCSAASSRAA----------- 2610
Query: 315 TLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSG 374
+P S+S+ + SSS S +SS+ +S + + SS +S ++SS S+ S S
Sbjct: 2611 ----SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
Query: 375 RMGPAM------------LRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPT-QP 421
+ PA AGP ++ K + A +P +P QP
Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726
Query: 422 QT-PEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKF 475
Q P Q L S+ K + + +K + +P+ N+ KI F
Sbjct: 2727 QAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAF 2781
Score = 37.4 bits (85), Expect = 0.051
Identities = 51/207 (24%), Positives = 76/207 (36%), Gaps = 17/207 (8%)
Query: 79 PPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFI 138
PPL + P SPL + ++++ + H L + QAAQA + Q + +
Sbjct: 879 PPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALE-----LQRSAQLV 933
Query: 139 QESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQAR 198
QE +LK E E K S L+ + G P LL P ++G
Sbjct: 934 QE-RLKAQEHRAEMEEKGSKRGLEA-------AGKAGLATAGPGLLPRKPPGLAAGPAGT 985
Query: 199 LTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKE 258
+A PP S A P + A + KP P S S P A+ P
Sbjct: 986 YGKAVSPPPSPRASPVAALKAKVIQKLEDVSKP-PAYAYPATPSSHPTSPPPASPPP--- 1041
Query: 259 IPASPSRTKIPAEKESHRDVLPDKPAP 285
P + + P +D+ +K AP
Sbjct: 1042 TPGITRKEEAPENVVEKKDLELEKEAP 1068
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 50.1 bits (118), Expect = 8e-06
Identities = 100/487 (20%), Positives = 165/487 (33%), Gaps = 86/487 (17%)
Query: 194 GAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAE 253
G R PGP + P++ A A G P A G P A+
Sbjct: 222 GPGTRSGTRPGP----FSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADG---PKASP 274
Query: 254 KPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLK 313
+ + +IP P ++P + + L PA P S P P +
Sbjct: 275 EARPQIPTKP---RVPGKLQE----LASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQ 327
Query: 314 KTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKS 373
+ L++ GS+S + + PV G K SE P ++ +
Sbjct: 328 ENLVEQAGSSSLVNGRLHELPV---------PKPRGTPKPSEGTPAPRKDPPWITLVQAE 378
Query: 374 GRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNS 433
+ PA L P+ GP S Q + E+A TA + P P
Sbjct: 379 PKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNP------------ 426
Query: 434 SCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQR 493
E + +K S S P T + P + I +S+PK +
Sbjct: 427 ----FEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGI---TPTSSPKTKKRPA 479
Query: 494 PQSCTSVGRVTVHSTPVRRSSGPA--PQSLLSARRVSALPTPASRRCSGL----PPMTPK 547
P++ S + +H++ + S P+ P LS V +L + ++ + +G PP PK
Sbjct: 480 PRA-PSASPLALHASRLSHSEPPSATPSPALS---VESLSSESASQTAGAELLEPPAVPK 535
Query: 548 TM-------PRAVGSPLCV--------------------PARRRSSEPRKNSAMRTEPTR 580
+ P G+P+ + P PR + +P +
Sbjct: 536 SSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAK 595
Query: 581 ESNRKTDSRLVDV-------SPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAK 633
+ T + L+ V SP SP +V + +P + + S AT+ A + +K
Sbjct: 596 PCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSK 655
Query: 634 PGGDAAP 640
P AP
Sbjct: 656 PVRPPAP 662
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 49.7 bits (117), Expect = 1e-05
Identities = 125/581 (21%), Positives = 204/581 (35%), Gaps = 110/581 (18%)
Query: 231 PGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIP--------AEKESHRDVLPDK 282
PGT + P P A P PA+P+ P A H P
Sbjct: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGH-PAGPPT 292
Query: 283 PAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSA 342
AP AV PAA + G A P P AP + GP GA++A
Sbjct: 293 AAP-AVPPPAAAQN-GGSAGAAPAP-----------APAAGGPAGVSGQPGP---GAAAA 336
Query: 343 CTSPAVGKAKSSE-------------FASIPAN--SSRPLSNISKSGRMGPAMLRP---- 383
+P V KA+S + AS PA+ +S + + PA + P
Sbjct: 337 APAPGV-KAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395
Query: 384 ---ALPAGPVGASSWQAKRVDVSELAAEQLTAPPSA-SPTQPQTPEGGGQWLNSS----- 434
LP G GA + R + + + T P+ +P PQ P+ N
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGM 455
Query: 435 -CAWSESSQL----NKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLS 489
SE+ QL + + + + +T + P P P I TP ++
Sbjct: 456 VLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIA 515
Query: 490 RAQRPQSC---TSVGRVTVH-STPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMT 545
R P + S + TV S ++RS G PQ +L +A A+ +G P
Sbjct: 516 RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTP--- 572
Query: 546 PKTMPRAVGSPLCVPARRRSSEPRKN----------SAMRTEPTRESNRKTDSRLVDVSP 595
+T+P A + + + KN S ++ T + ++ L+D
Sbjct: 573 QRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKI 632
Query: 596 DRGSPPSRVPQALNFSPEESDSTFSK-----------STATEVAREEAKPGGDAAPSEAL 644
+ SR+ + LN SP+ F K +A + + + +P + +
Sbjct: 633 EAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTA 692
Query: 645 LVDIKLE--------PLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNT 696
L + L A T +A QP P++ T V VG + +P T
Sbjct: 693 LTAVVLSSSVQRTAGKTAATVTSALQP----PVLSL--TQPTQVGVGKQGQP-------T 739
Query: 697 PDMNKNVAKPSPVV--GQLIDLSSPLIQLSPEADKENVDSP 735
P + + KP ++ Q+ +P++ L ++ + +P
Sbjct: 740 PLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP 780
Score = 38.5 bits (88), Expect = 0.023
Identities = 84/353 (23%), Positives = 117/353 (33%), Gaps = 51/353 (14%)
Query: 266 TKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGST-- 323
+++ A H + P P A A G+H+ G A G APG+
Sbjct: 31 SQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAG--AGPAAPAEGAPGAAPE 88
Query: 324 ---SNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAM 380
+ AR GP G S P V + PA RP S +G P
Sbjct: 89 PPPAGRARPGGGGPQRPGPPSP-RRPLVPAGPAP-----PAAKLRPPPEGS-AGSCAPVP 141
Query: 381 LRPALPAGPVGASSWQAKRVDVSELAAEQLTAP-------PSASPTQPQTPEGGGQWLNS 433
A+ AGP A + AK + LAA P P P +P P G Q LN
Sbjct: 142 AAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP-GAAQTLNG 200
Query: 434 SCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQR 493
S A LN + S +N+ P +PK + + + P + A
Sbjct: 201 SAA-----LLNSHHAAAPAVSLVNN------GPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
Query: 494 P-QSCTSVGRVTVHSTPVRRSSGPAPQSLLSAR----------RVSALPTPASRRCSGLP 542
P + S + P P P AR A+P PA+ + G
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA 309
Query: 543 PMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSP 595
P P A G P V S +P +A P ++ R+V +P
Sbjct: 310 GAAPAPAP-AAGGPAGV-----SGQPGPGAA-AAAPAPGVKAESPKRVVQAAP 355
>gi|197276670 spermatogenesis and centriole associated 1 isoform 2
[Homo sapiens]
Length = 441
Score = 49.3 bits (116), Expect = 1e-05
Identities = 83/340 (24%), Positives = 122/340 (35%), Gaps = 53/340 (15%)
Query: 311 GLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNI 370
G TLL P TS S P+ S +S P G SS +
Sbjct: 119 GTLSTLLSGPAPTSQ------SSPLTSFLTSPIAGPLTGTLASS-------------LGL 159
Query: 371 SKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQW 430
+G + P+ +L AGPV S V A L++P +S TP G Q
Sbjct: 160 PSTGTLTPS----SLVAGPVAMSQSSPLIAPVMGTVAVSLSSPLLSSTA---TPPGVSQN 212
Query: 431 L----NSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTP 486
L S+ E+ +L +R + S V+PT T K+P + P
Sbjct: 213 LLANPMSNLVLPEAPRLRLAEPLRGGPTGPQSPACVVPTATT--KVPL-------STEPP 263
Query: 487 KLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLP---P 543
+ ++ P S G STP+ PAP++ S P++ + +P P
Sbjct: 264 QSTQDPEPLSMAFAGAPLQTSTPIGAMGTPAPKTAFSFNTSDTQAQPSAAQEQVVPASVP 323
Query: 544 MTPKTMPRA---VGSPLCVPARRRSSEPRKNSAMRT----EPTRESNRKTDSRLVDVSPD 596
+P T P +P P S P + + P+R N T + V P
Sbjct: 324 TSPTTSPTVTVLASAPALAPQVATSYTPSSTTHIAQGAPHPPSRMHNSPTQNLPVPHCPP 383
Query: 597 RG--SPP--SRVPQALNFSPEESDSTFSKSTATEVAREEA 632
SPP S P ++N S + S + EV R+ A
Sbjct: 384 HNAHSPPRTSSSPASVNDSRGPRTTEPSTKSMMEVERKLA 423
Score = 31.6 bits (70), Expect = 2.8
Identities = 38/148 (25%), Positives = 55/148 (37%), Gaps = 26/148 (17%)
Query: 157 SPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP--- 213
+PTS SP+ GP G LASS LPS+G + GP + + P
Sbjct: 129 APTSQSSPLTSFLTSPIAGPLTGT---LASSLGLPSTGTLTPSSLVAGPVAMSQSSPLIA 185
Query: 214 ------RESCTAHAASQAATQ--------RKPGTKLLLPRAASVR----GRSIPGAAEKP 255
S ++ S AT P + L+LP A +R R P + P
Sbjct: 186 PVMGTVAVSLSSPLLSSTATPPGVSQNLLANPMSNLVLPEAPRLRLAEPLRGGPTGPQSP 245
Query: 256 KKEIPASPSRTKIPAEKESHRDVLPDKP 283
+P + TK+P E + +P
Sbjct: 246 ACVVPT--ATTKVPLSTEPPQSTQDPEP 271
>gi|197276668 spermatogenesis and centriole associated 1 isoform 1
[Homo sapiens]
Length = 591
Score = 49.3 bits (116), Expect = 1e-05
Identities = 83/340 (24%), Positives = 122/340 (35%), Gaps = 53/340 (15%)
Query: 311 GLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNI 370
G TLL P TS S P+ S +S P G SS +
Sbjct: 119 GTLSTLLSGPAPTSQ------SSPLTSFLTSPIAGPLTGTLASS-------------LGL 159
Query: 371 SKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQW 430
+G + P+ +L AGPV S V A L++P +S TP G Q
Sbjct: 160 PSTGTLTPS----SLVAGPVAMSQSSPLIAPVMGTVAVSLSSPLLSSTA---TPPGVSQN 212
Query: 431 L----NSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTP 486
L S+ E+ +L +R + S V+PT T K+P + P
Sbjct: 213 LLANPMSNLVLPEAPRLRLAEPLRGGPTGPQSPACVVPTATT--KVPL-------STEPP 263
Query: 487 KLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLP---P 543
+ ++ P S G STP+ PAP++ S P++ + +P P
Sbjct: 264 QSTQDPEPLSMAFAGAPLQTSTPIGAMGTPAPKTAFSFNTSDTQAQPSAAQEQVVPASVP 323
Query: 544 MTPKTMPRA---VGSPLCVPARRRSSEPRKNSAMRT----EPTRESNRKTDSRLVDVSPD 596
+P T P +P P S P + + P+R N T + V P
Sbjct: 324 TSPTTSPTVTVLASAPALAPQVATSYTPSSTTHIAQGAPHPPSRMHNSPTQNLPVPHCPP 383
Query: 597 RG--SPP--SRVPQALNFSPEESDSTFSKSTATEVAREEA 632
SPP S P ++N S + S + EV R+ A
Sbjct: 384 HNAHSPPRTSSSPASVNDSRGPRTTEPSTKSMMEVERKLA 423
Score = 31.6 bits (70), Expect = 2.8
Identities = 38/148 (25%), Positives = 55/148 (37%), Gaps = 26/148 (17%)
Query: 157 SPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP--- 213
+PTS SP+ GP G LASS LPS+G + GP + + P
Sbjct: 129 APTSQSSPLTSFLTSPIAGPLTGT---LASSLGLPSTGTLTPSSLVAGPVAMSQSSPLIA 185
Query: 214 ------RESCTAHAASQAATQ--------RKPGTKLLLPRAASVR----GRSIPGAAEKP 255
S ++ S AT P + L+LP A +R R P + P
Sbjct: 186 PVMGTVAVSLSSPLLSSTATPPGVSQNLLANPMSNLVLPEAPRLRLAEPLRGGPTGPQSP 245
Query: 256 KKEIPASPSRTKIPAEKESHRDVLPDKP 283
+P + TK+P E + +P
Sbjct: 246 ACVVPT--ATTKVPLSTEPPQSTQDPEP 271
Score = 30.0 bits (66), Expect = 8.1
Identities = 28/113 (24%), Positives = 46/113 (40%), Gaps = 13/113 (11%)
Query: 157 SPTSLKRETYYLSDSPLLGP-------PVGEPRLLASSPALPSSGAQARLTRAPGP---P 206
SPT+ T L+ +P L P P + +P PS + P P P
Sbjct: 325 SPTTSPTVTV-LASAPALAPQVATSYTPSSTTHIAQGAPHPPSRMHNSPTQNLPVPHCPP 383
Query: 207 HSAHALPRESCTAHAASQAATQR--KPGTKLLLPRAASVRGRSIPGAAEKPKK 257
H+AH+ PR S + + + + R +P TK ++ + R E P++
Sbjct: 384 HNAHSPPRTSSSPASVNDSRGPRTTEPSTKSMMEVERKLAHRKTSKFPENPRE 436
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 48.9 bits (115), Expect = 2e-05
Identities = 117/516 (22%), Positives = 172/516 (33%), Gaps = 76/516 (14%)
Query: 179 GEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAAT--QRKPG---- 232
G PR S + S G Q T P S H P TA A + +T R PG
Sbjct: 601 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 660
Query: 233 ----------------------------TKLLLPRAASVRGRSIPGAAEKPKKEIPASPS 264
T S RG S EI P
Sbjct: 661 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 720
Query: 265 RTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS 324
T P E+ +P PA+ + LG G+ + ++ G + + +P ST+
Sbjct: 721 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV-SPASTT 779
Query: 325 NLARKSSSGPVWSGASSA--------CTSPAVGKAKSSEFASIPANSSRPLSNISKSGRM 376
S V+S + + T+ +V + + F S PA++ L S
Sbjct: 780 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT-EDSTTS 838
Query: 377 GPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCA 436
G A P P + + ++L E T P S+ T + S A
Sbjct: 839 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL----------SPA 888
Query: 437 WSESSQLNKTRSIRRRDSCLNSKTKVMP----TPTNQFKIPKFSIGDSPDSSTPKLSRAQ 492
S +S L S R S +++T +P TP+ K F SP S LS A
Sbjct: 889 RSTTSGL-VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY--TSPRSPDATLSPAT 945
Query: 493 RPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTP-KTMPR 551
S S T HS P + P S ++ T S + S ++P T
Sbjct: 946 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS 1005
Query: 552 AVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVS-PDRGSPPS----RVPQ 606
++G + S +S TE T + S LV+ S P S S P
Sbjct: 1006 SLG---------QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 1056
Query: 607 ALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ + + +ST +S + + PG AAP E
Sbjct: 1057 SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVE 1092
Score = 40.0 bits (92), Expect = 0.008
Identities = 100/481 (20%), Positives = 159/481 (33%), Gaps = 75/481 (15%)
Query: 161 LKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALP----RES 216
L+ E+ P P ++P S+ +R + P SA + ES
Sbjct: 1063 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1122
Query: 217 CTAHAASQAATQRKPGTKLLLPRAAS--VRGRSIPGAAEKPKKEIPASPSRTKIPAEKES 274
T H++ A GT L R+A+ + G E A P T E
Sbjct: 1123 TTVHSSPGAT-----GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 1177
Query: 275 HRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTS-------NLA 327
+P PA+ + G + + ++ G T PGST+ + A
Sbjct: 1178 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTA-FPGSTTMPGVSQESTA 1236
Query: 328 RKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPA 387
SS G + S T+ + +S+ F S P ++ L LP
Sbjct: 1237 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL-----------------LPD 1279
Query: 388 GPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTR 447
+ +A S + T P+ S T+ W +S ++ T
Sbjct: 1280 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSK----DTMPAPPTT 1335
Query: 448 SIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHS 507
+ + S TPT F ++G S +S+T VHS
Sbjct: 1336 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT-------------------VHS 1376
Query: 508 TPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSE 567
+PV ++ P+P AR ++ S P T + + P A RS E
Sbjct: 1377 SPVATATTPSP-----ARSTTSGLVEESTAYHSSPGST-----QTMHFPESSTASGRSEE 1426
Query: 568 PRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRV-----PQALNFSPEESDSTFSKS 622
R + + T T S T S LV+ S P + P++ S +ST S S
Sbjct: 1427 SRTSHSSTTH-TISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHS 1485
Query: 623 T 623
+
Sbjct: 1486 S 1486
Score = 34.7 bits (78), Expect = 0.33
Identities = 111/506 (21%), Positives = 181/506 (35%), Gaps = 61/506 (12%)
Query: 155 KKSPTSLKRETYYLSDSP-LLGPPVGEPRLLASSPA------LPSSGAQARLTRAPGPPH 207
++S TS T+ +S +P V EP SSP P S + + H
Sbjct: 342 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 401
Query: 208 SAH------ALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKK--EI 259
S+ LP S T+ ++ T P + + A + PG +E+
Sbjct: 402 SSQDATGTIVLPARSTTSVLLGESTTS--PISSGSMETTALPGSTTTPGLSERSTTFHSS 459
Query: 260 PASPSRTKIPAEKESH---RDVLPDKPAPGAVNV---PAAGSHLGQGKRAIPVPNKLG-L 312
P SP+ T PA S + + PG+ + P + + G + + + G
Sbjct: 460 PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 519
Query: 313 KKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKA-----KSSEFASIPANSSRPL 367
TLL A +TS +++S++ SG++ SP A +S+ F S P ++ L
Sbjct: 520 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 579
Query: 368 SNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGG 427
S + +G V AS+ RV S + +P S++ Q
Sbjct: 580 FPDSTTS------------SGIVEAST----RVHSSTGSPRTTLSPASSTSPGLQGESTA 623
Query: 428 GQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPK 487
Q +S + S T + + S TPT F + G S S+
Sbjct: 624 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS---TPTTHFPASSTTSGHSEKST--- 677
Query: 488 LSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGL--PPMT 545
+ + S T+ + HST R G + S +S P S GL T
Sbjct: 678 IFHSSPDASGTTPS--SAHSTTSGR--GESTTSRISPGSTEITTLPGSTTTPGLSEASTT 733
Query: 546 PKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVP 605
+ PR+ + L + +++ R++P S T S +P + V
Sbjct: 734 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP--GSTHSTVSPASTTTPGLSEESTTVY 791
Query: 606 QALNFSPEESDSTFSKSTATEVAREE 631
+ S E + F ST T V EE
Sbjct: 792 SSSRGSTE--TTVFPHSTTTSVHGEE 815
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 48.5 bits (114), Expect = 2e-05
Identities = 126/589 (21%), Positives = 195/589 (33%), Gaps = 85/589 (14%)
Query: 116 SRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLG 175
++ + A P P G S+ K E++ E +S E + + L
Sbjct: 307 AKGTPGKGATPAPPGKAGAVA----SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 362
Query: 176 PPVGEPRLL--ASSPALPSSGAQARLTRAPGPPHS-------AHALPRE------SCTAH 220
G+ + AS+PA S R AP PP A A RE S +
Sbjct: 363 KASGKTSQVGAASAPAKESP----RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418
Query: 221 AASQAATQRKPGTKLLLPRAASVRGRSIP--GAAEKPKKEIPASPSRTKIPAEKESHR-- 276
+ +A Q KP K RAAS + P GAA P ++ + ++ ++ ++E R
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
Query: 277 --DVLPDKPAPGAVNV-------------PAAGSHLGQ-GKRAIPVPNKLGLKKTLLKAP 320
+ D+ A A+N PA+ +G GK A PVP P
Sbjct: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP------------P 526
Query: 321 GSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAM 380
G + G W S + + + + ++ + L NI ++
Sbjct: 527 GKVGPATPSAQVGK-WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 381 LRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSES 440
P AGPV K +D SE + E + S T L +
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
Query: 441 SQLNKTRSIR-----------RRDSCLNSKTKVMPTPTNQFKIP--KFSIGDSPDSSTPK 487
+ N T S + R+ S P + P S + DS K
Sbjct: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 705
Query: 488 LSRAQRPQSCTSVGR---VTVHSTPVRRSSGPAPQSLLSARR-VSALPTPASRRCSGLPP 543
A SVG+ V S PV+ S G +L + + A ++
Sbjct: 706 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 765
Query: 544 MTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDV-------SPD 596
A SP V + ++ + N A P+ + ++V SP
Sbjct: 766 EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 597 RGSPPSRVPQ---ALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ PP R PQ L P S K+ AT A+ + P D+ SE
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSV-GKAVAT-AAQAQTGPEEDSGSSE 872
Score = 42.7 bits (99), Expect = 0.001
Identities = 115/531 (21%), Positives = 190/531 (35%), Gaps = 58/531 (10%)
Query: 123 AAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPR 182
AAKP + + +++ + + E + P +K + +SP +
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK 244
Query: 183 LLASSPALPSSGAQARLTRAPGPPHSAHALPRES-CTAHAASQAATQRKPGTKLLLPRAA 241
+ +P + GA RA P + + S A + +Q K K+L RAA
Sbjct: 245 VGDVTPQV-KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
Query: 242 SVRGRSIP--GAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQ 299
S + P GA P + A S+TK + E + ++ + PAA + L
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVASQTK-AGKPEEDSESSSEESSDSEEETPAAKALL-- 360
Query: 300 GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASI 359
K K + + A + + + + + P G T PAV KA++ +
Sbjct: 361 -------QAKASGKTSQVGAASAPAKESPRKGAAPAPPGK----TGPAVAKAQAGK---- 405
Query: 360 PANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPT 419
S+ S S S PA +P+ A V A+S AK A APP +
Sbjct: 406 REEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA----PAPPRKTGP 461
Query: 420 QPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGD 479
+ G Q +S + ES S R + +N+ +V P + P ++G
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESD------SDREALAAMNA-AQVKPLGKSPQVKPASTMGM 514
Query: 480 SPDSSTPKLSRAQRPQSCTSVGRVT----VHSTPVRRSSGPAPQSLLSARRVSALPTPAS 535
P L + P VG T V S S S V PA
Sbjct: 515 GP------LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
Query: 536 RRCSG-----LPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRL 590
+ G P +P P P+ V ++ +P NS E + ES+ DS
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQV--KAEKPMDNS----ESSEESSDSADSEE 622
Query: 591 VD--VSPDRGSPPSRVPQALNFSPEESDSTFSKSTA-TEVAREEAKPGGDA 638
++ + P ++PQ P+++++T S A V + + G A
Sbjct: 623 APAAMTAAQAKPALKIPQT-KACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Score = 41.6 bits (96), Expect = 0.003
Identities = 90/407 (22%), Positives = 150/407 (36%), Gaps = 65/407 (15%)
Query: 295 SHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSS 354
S LG+ KR L KKT + P STS +SS + A +A +P + SS
Sbjct: 57 SELGR-KRKAEEDAALQAKKTRVSDPISTS----ESSEEEEEAEAETAKATPRLASTNSS 111
Query: 355 EF-ASIPAN-SSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTA 412
A +P++ + + K+G+ G +M PA S ++ R A L +
Sbjct: 112 VLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVS 171
Query: 413 PPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRS----IRRRDSCLNSKTKVMPTPTN 468
+ P + S+ SS+ + S + + S ++ K T
Sbjct: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
Query: 469 QFKIPKFS-----IGD-SPD---SSTPKLSRAQRPQS---CTSVGRVTVHSTPV-RRSSG 515
+ K + +GD +P + P RA++P+ + G + P RS
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 516 PAPQSLLSARRVSALP--TPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSA 573
A + +L R SA TP G P P G V ++ ++ +P ++S
Sbjct: 292 KASEKILQVRAASAPAKGTPGK----GATPAPP-------GKAGAVASQTKAGKPEEDSE 340
Query: 574 MRTEPTRESNRKTD--------------------SRLVDVSPDRGS---PPSRVPQALNF 610
+E + +S +T S SP +G+ PP + A+
Sbjct: 341 SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAK 400
Query: 611 SP-----EESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEP 652
+ E+S S+ +S + E A +AKP G A A K P
Sbjct: 401 AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 48.5 bits (114), Expect = 2e-05
Identities = 126/589 (21%), Positives = 195/589 (33%), Gaps = 85/589 (14%)
Query: 116 SRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLG 175
++ + A P P G S+ K E++ E +S E + + L
Sbjct: 307 AKGTPGKGATPAPPGKAGAVA----SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 362
Query: 176 PPVGEPRLL--ASSPALPSSGAQARLTRAPGPPHS-------AHALPRE------SCTAH 220
G+ + AS+PA S R AP PP A A RE S +
Sbjct: 363 KASGKTSQVGAASAPAKESP----RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418
Query: 221 AASQAATQRKPGTKLLLPRAASVRGRSIP--GAAEKPKKEIPASPSRTKIPAEKESHR-- 276
+ +A Q KP K RAAS + P GAA P ++ + ++ ++ ++E R
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
Query: 277 --DVLPDKPAPGAVNV-------------PAAGSHLGQ-GKRAIPVPNKLGLKKTLLKAP 320
+ D+ A A+N PA+ +G GK A PVP P
Sbjct: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP------------P 526
Query: 321 GSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAM 380
G + G W S + + + + ++ + L NI ++
Sbjct: 527 GKVGPATPSAQVGK-WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 381 LRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSES 440
P AGPV K +D SE + E + S T L +
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
Query: 441 SQLNKTRSIR-----------RRDSCLNSKTKVMPTPTNQFKIP--KFSIGDSPDSSTPK 487
+ N T S + R+ S P + P S + DS K
Sbjct: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 705
Query: 488 LSRAQRPQSCTSVGR---VTVHSTPVRRSSGPAPQSLLSARR-VSALPTPASRRCSGLPP 543
A SVG+ V S PV+ S G +L + + A ++
Sbjct: 706 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 765
Query: 544 MTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDV-------SPD 596
A SP V + ++ + N A P+ + ++V SP
Sbjct: 766 EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 597 RGSPPSRVPQ---ALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSE 642
+ PP R PQ L P S K+ AT A+ + P D+ SE
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSV-GKAVAT-AAQAQTGPEEDSGSSE 872
Score = 42.7 bits (99), Expect = 0.001
Identities = 115/531 (21%), Positives = 190/531 (35%), Gaps = 58/531 (10%)
Query: 123 AAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPR 182
AAKP + + +++ + + E + P +K + +SP +
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK 244
Query: 183 LLASSPALPSSGAQARLTRAPGPPHSAHALPRES-CTAHAASQAATQRKPGTKLLLPRAA 241
+ +P + GA RA P + + S A + +Q K K+L RAA
Sbjct: 245 VGDVTPQV-KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
Query: 242 SVRGRSIP--GAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQ 299
S + P GA P + A S+TK + E + ++ + PAA + L
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVASQTK-AGKPEEDSESSSEESSDSEEETPAAKALL-- 360
Query: 300 GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASI 359
K K + + A + + + + + P G T PAV KA++ +
Sbjct: 361 -------QAKASGKTSQVGAASAPAKESPRKGAAPAPPGK----TGPAVAKAQAGK---- 405
Query: 360 PANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPT 419
S+ S S S PA +P+ A V A+S AK A APP +
Sbjct: 406 REEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA----PAPPRKTGP 461
Query: 420 QPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGD 479
+ G Q +S + ES S R + +N+ +V P + P ++G
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESD------SDREALAAMNA-AQVKPLGKSPQVKPASTMGM 514
Query: 480 SPDSSTPKLSRAQRPQSCTSVGRVT----VHSTPVRRSSGPAPQSLLSARRVSALPTPAS 535
P L + P VG T V S S S V PA
Sbjct: 515 GP------LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
Query: 536 RRCSG-----LPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRL 590
+ G P +P P P+ V ++ +P NS E + ES+ DS
Sbjct: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQV--KAEKPMDNS----ESSEESSDSADSEE 622
Query: 591 VD--VSPDRGSPPSRVPQALNFSPEESDSTFSKSTA-TEVAREEAKPGGDA 638
++ + P ++PQ P+++++T S A V + + G A
Sbjct: 623 APAAMTAAQAKPALKIPQT-KACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Score = 41.6 bits (96), Expect = 0.003
Identities = 90/407 (22%), Positives = 150/407 (36%), Gaps = 65/407 (15%)
Query: 295 SHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSS 354
S LG+ KR L KKT + P STS +SS + A +A +P + SS
Sbjct: 57 SELGR-KRKAEEDAALQAKKTRVSDPISTS----ESSEEEEEAEAETAKATPRLASTNSS 111
Query: 355 EF-ASIPAN-SSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTA 412
A +P++ + + K+G+ G +M PA S ++ R A L +
Sbjct: 112 VLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVS 171
Query: 413 PPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRS----IRRRDSCLNSKTKVMPTPTN 468
+ P + S+ SS+ + S + + S ++ K T
Sbjct: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
Query: 469 QFKIPKFS-----IGD-SPD---SSTPKLSRAQRPQS---CTSVGRVTVHSTPV-RRSSG 515
+ K + +GD +P + P RA++P+ + G + P RS
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 516 PAPQSLLSARRVSALP--TPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSA 573
A + +L R SA TP G P P G V ++ ++ +P ++S
Sbjct: 292 KASEKILQVRAASAPAKGTPGK----GATPAPP-------GKAGAVASQTKAGKPEEDSE 340
Query: 574 MRTEPTRESNRKTD--------------------SRLVDVSPDRGS---PPSRVPQALNF 610
+E + +S +T S SP +G+ PP + A+
Sbjct: 341 SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAK 400
Query: 611 SP-----EESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEP 652
+ E+S S+ +S + E A +AKP G A A K P
Sbjct: 401 AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,693,234
Number of Sequences: 37866
Number of extensions: 1958586
Number of successful extensions: 9711
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 701
Number of HSP's that attempted gapping in prelim test: 8278
Number of HSP's gapped (non-prelim): 1948
length of query: 739
length of database: 18,247,518
effective HSP length: 110
effective length of query: 629
effective length of database: 14,082,258
effective search space: 8857740282
effective search space used: 8857740282
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.