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Search of human proteins with 24797151
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797151 dimethylglycine dehydrogenase precursor [Homo
sapiens]
(866 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens] 1764 0.0
gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens] 431 e-120
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens] 431 e-120
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun... 363 e-100
gi|44662838 aminomethyltransferase [Homo sapiens] 91 6e-18
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom... 64 8e-10
gi|60499001 pipecolic acid oxidase [Homo sapiens] 60 9e-09
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 46 2e-04
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 46 2e-04
gi|28559080 spermine oxidase isoform 4 [Homo sapiens] 32 1.9
gi|28559078 spermine oxidase isoform 3 [Homo sapiens] 32 1.9
gi|28559076 spermine oxidase isoform 2 [Homo sapiens] 32 1.9
gi|28559074 spermine oxidase isoform 1 [Homo sapiens] 32 1.9
gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo s... 32 1.9
gi|169206326 PREDICTED: hypothetical protein [Homo sapiens] 32 2.5
gi|169206576 PREDICTED: hypothetical protein [Homo sapiens] 32 2.5
gi|169205717 PREDICTED: hypothetical protein [Homo sapiens] 32 2.5
gi|170650615 protoporphyrinogen oxidase [Homo sapiens] 32 2.5
gi|4506001 protoporphyrinogen oxidase [Homo sapiens] 32 2.5
gi|39995071 exonuclease 1 isoform b [Homo sapiens] 32 3.3
gi|39995069 exonuclease 1 isoform a [Homo sapiens] 32 3.3
gi|18491016 exonuclease 1 isoform b [Homo sapiens] 32 3.3
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens] 32 3.3
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens] 32 3.3
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens] 31 5.7
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens] 31 5.7
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens] 31 5.7
gi|224586807 zinc finger protein 181 isoform 2 [Homo sapiens] 31 5.7
gi|224586802 zinc finger protein 181 isoform 1 [Homo sapiens] 31 5.7
gi|197100773 arginyl-tRNA synthetase 2, mitochondrial precursor ... 31 5.7
>gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens]
Length = 866
Score = 1764 bits (4570), Expect = 0.0
Identities = 866/866 (100%), Positives = 866/866 (100%)
Query: 1 MLRPGAQLLRGLLLRSCPLQGSPGRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCV 60
MLRPGAQLLRGLLLRSCPLQGSPGRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCV
Sbjct: 1 MLRPGAQLLRGLLLRSCPLQGSPGRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCV 60
Query: 61 GVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLE 120
GVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLE
Sbjct: 61 GVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLE 120
Query: 121 EETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNK 180
EETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNK
Sbjct: 121 EETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNK 180
Query: 181 VLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMR 240
VLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMR
Sbjct: 181 VLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMR 240
Query: 241 ANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYL 300
ANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYL
Sbjct: 241 ANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYL 300
Query: 301 RQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLK 360
RQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLK
Sbjct: 301 RQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLK 360
Query: 361 KADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP 420
KADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP
Sbjct: 361 KADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP 420
Query: 421 PFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLES 480
PFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLES
Sbjct: 421 PFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLES 480
Query: 481 KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKF 540
KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKF
Sbjct: 481 KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKF 540
Query: 541 NIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSE 600
NIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSE
Sbjct: 541 NIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSE 600
Query: 601 LHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK 660
LHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK
Sbjct: 601 LHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK 660
Query: 661 SLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRL 720
SLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRL
Sbjct: 661 SLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRL 720
Query: 721 EKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATD 780
EKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATD
Sbjct: 721 EKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATD 780
Query: 781 DVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPA 840
DVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPA
Sbjct: 781 DVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPA 840
Query: 841 VIIQEPLVLTEPTRNRLQKKGGKDKT 866
VIIQEPLVLTEPTRNRLQKKGGKDKT
Sbjct: 841 VIIQEPLVLTEPTRNRLQKKGGKDKT 866
>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
Length = 918
Score = 431 bits (1108), Expect = e-120
Identities = 279/845 (33%), Positives = 433/845 (51%), Gaps = 66/845 (7%)
Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG-INLKKI 108
A V+IGGG +G YHLAK GM VLLE+ LT+G+TWH AGL P + ++ +
Sbjct: 67 ANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELL 126
Query: 109 HYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEK 168
+ + +LEEETG G+ Q G + +A+ R+DE+K M+ + E +++ P +
Sbjct: 127 AHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAE 186
Query: 169 IQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228
+ ++PL+N++ + LY P DG +DP LA A GA + PVT ++ +D
Sbjct: 187 TKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDD 246
Query: 229 -----TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKA 283
VET GS++ +VN AG WA VG+M G++ PL+ + H YVVT I ++
Sbjct: 247 FGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQ- 305
Query: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLD 343
+P +RD + S YLR + D L G YE+ W V F LF+ D +
Sbjct: 306 ---NMPNVRDHDASVYLRLQGDALSVGGYEANPIF-----W--EEVSDKFAFGLFDLDWE 355
Query: 344 RIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGY-GII 402
+HI+ A+ VPVL+K I + V GP +++PD P++G +R +++ GF G++
Sbjct: 356 VFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMM 415
Query: 403 HAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT--QYTEAKARESYGFNNIVGYPKE 460
GG G+ L+ WI+HG P D+ D R+ T ++ ++ ESY N V +P +
Sbjct: 416 LGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHD 475
Query: 461 ERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPG------------------QD 502
E AGR +R + L C GWE+P WF+ G +D
Sbjct: 476 EPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHED 535
Query: 503 TQYRP------SFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLF- 555
YR +F + + E AV D+S FGKF + G D+ + D LF
Sbjct: 536 YAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFS 595
Query: 556 ANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGE-------------FLLITGSGSELH 602
A+V G T + ML +G ++LTVS +P + L G H
Sbjct: 596 ADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQH 655
Query: 603 DLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSL 662
+ I ++ + +++LG++ + GP +R +LQ++ DLS++ F F K L
Sbjct: 656 NWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLL 715
Query: 663 KVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEK 722
+ + V A+R+S+ GELGWEL+ + V +Y A+M AG + G+ N G A+++L +EK
Sbjct: 716 RAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEK 775
Query: 723 AFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDV 782
+R W ++ D +PLEAGL + KL P F+G++AL+Q +A GL+RRLVC T+ D V
Sbjct: 776 GYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTM-EDKV 834
Query: 783 DPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYV------PVQLSEV-GQQVEVELLG 835
G E+IW NG+VVG+ + ++I K++A+ Y+ PV L V +E +G
Sbjct: 835 PMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMG 894
Query: 836 KNYPA 840
Y A
Sbjct: 895 VTYGA 899
>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
Length = 918
Score = 431 bits (1108), Expect = e-120
Identities = 279/845 (33%), Positives = 433/845 (51%), Gaps = 66/845 (7%)
Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG-INLKKI 108
A V+IGGG +G YHLAK GM VLLE+ LT+G+TWH AGL P + ++ +
Sbjct: 67 ANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELL 126
Query: 109 HYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEK 168
+ + +LEEETG G+ Q G + +A+ R+DE+K M+ + E +++ P +
Sbjct: 127 AHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAE 186
Query: 169 IQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228
+ ++PL+N++ + LY P DG +DP LA A GA + PVT ++ +D
Sbjct: 187 TKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDD 246
Query: 229 -----TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKA 283
VET GS++ +VN AG WA VG+M G++ PL+ + H YVVT I ++
Sbjct: 247 FGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQ- 305
Query: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLD 343
+P +RD + S YLR + D L G YE+ W V F LF+ D +
Sbjct: 306 ---NMPNVRDHDASVYLRLQGDALSVGGYEANPIF-----W--EEVSDKFAFGLFDLDWE 355
Query: 344 RIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGY-GII 402
+HI+ A+ VPVL+K I + V GP +++PD P++G +R +++ GF G++
Sbjct: 356 VFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMM 415
Query: 403 HAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT--QYTEAKARESYGFNNIVGYPKE 460
GG G+ L+ WI+HG P D+ D R+ T ++ ++ ESY N V +P +
Sbjct: 416 LGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHD 475
Query: 461 ERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPG------------------QD 502
E AGR +R + L C GWE+P WF+ G +D
Sbjct: 476 EPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHED 535
Query: 503 TQYRP------SFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLF- 555
YR +F + + E AV D+S FGKF + G D+ + D LF
Sbjct: 536 YAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFS 595
Query: 556 ANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGE-------------FLLITGSGSELH 602
A+V G T + ML +G ++LTVS +P + L G H
Sbjct: 596 ADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQH 655
Query: 603 DLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSL 662
+ I ++ + +++LG++ + GP +R +LQ++ DLS++ F F K L
Sbjct: 656 NWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLL 715
Query: 663 KVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEK 722
+ + V A+R+S+ GELGWEL+ + V +Y A+M AG + G+ N G A+++L +EK
Sbjct: 716 RAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEK 775
Query: 723 AFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDV 782
+R W ++ D +PLEAGL + KL P F+G++AL+Q +A GL+RRLVC T+ D V
Sbjct: 776 GYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTM-EDKV 834
Query: 783 DPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYV------PVQLSEV-GQQVEVELLG 835
G E+IW NG+VVG+ + ++I K++A+ Y+ PV L V +E +G
Sbjct: 835 PMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMG 894
Query: 836 KNYPA 840
Y A
Sbjct: 895 VTYGA 899
>gi|194306651 pyruvate dehydrogenase phosphatase regulatory subunit
[Homo sapiens]
Length = 879
Score = 363 bits (932), Expect = e-100
Identities = 254/804 (31%), Positives = 415/804 (51%), Gaps = 42/804 (5%)
Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG-LTTYFHPGINLKK 107
+A+ VI GGG G S+AYHL+K G KD+VLLE+ L AGST AG L+T H I K
Sbjct: 42 QAQVVICGGGITGTSVAYHLSKMGWKDIVLLEQGRLAAGSTRFCAGILSTARHLTIEQKM 101
Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167
Y + KLY +LE+ETG G+ + GSI LA T R+ K +I P+
Sbjct: 102 ADYSN-KLYYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPK 160
Query: 168 KIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSD 227
K+ E+ LLN++ ++ ++ P D + + +ALA+ A + G + V + +
Sbjct: 161 KVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKG 220
Query: 228 GTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPL-IPV---QHQYVVTSTISEVKA 283
VET +G + VN AG WA E+G + E P+ IP+ +H Y++T +
Sbjct: 221 QVTGVETDKGQIECQYFVNCAGQWAYELG--LSNEEPVSIPLHACEHFYLLTRPLET--P 276
Query: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFE---- 339
L+ P + D +G Y+R + G+L G +E K + GK E
Sbjct: 277 LQSSTPTIVDADGRIYIRNWQGGILSGGFEKNPKPIFTE-----------GKNQLEIQNL 325
Query: 340 -SDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFG 398
D D + + + +P L+ +I+ +VN P T++PD+ ++G V+ Y+V G
Sbjct: 326 QEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDMRCIMGESPAVQGYFVLAGMN 385
Query: 399 Y-GIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQ-YTEAKARESYGFNNIVG 456
G+ GG GKYL++W++HG P ++ ELD R+G +++ + + E +
Sbjct: 386 SAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLMYDLK 445
Query: 457 YPKEERFAGRPTQRVSGLYQRLESKCSMGFHA-GWEQPHWFYKPGQDT---QYRPSFRRT 512
P+ + GR R S LY RL+++ + G+E+P +F P +D + +F +
Sbjct: 446 VPRWDFQTGRQL-RTSPLYDRLDAQGARWMEKHGFERPKYFVPPDKDLLALEQSKTFYKP 504
Query: 513 NWFEPVGSEYKQVMQRVAVTDLSPFGKFNIK--GQDSIRLLDHLFANVIP-KVGFTNISH 569
+WF+ V SE K + V V D+S F KF I G ++ +L +LF+N + VG +
Sbjct: 505 DWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTG 564
Query: 570 MLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGV 629
ML G + +++ + F +I+ + ++H W+++ K ++ ++++T +
Sbjct: 565 MLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDS-NLLLEDVTWKYTA 623
Query: 630 LGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIP-VTAIRISYTGELGWELYHRR 688
L + GP+A VL +L+ ++ D F L K + V + + +++TGE G+ LY
Sbjct: 624 LNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPI 683
Query: 689 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL 748
E ++ +Y+ +M+ GQ+ GI N G YA+ +LR+EK F WG ++N T PLE G E VKL
Sbjct: 684 EYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKL 743
Query: 749 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVD----PEGNESIWYNGKVVGNTTSGS 804
K DFIG+ AL Q K G+ +RL L D D P E I+ NG+ VG TTS +
Sbjct: 744 EKGMDFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWGEPIYRNGQYVGKTTSSA 803
Query: 805 YSYSIQKSLAFAYVPVQLSEVGQQ 828
YSYS+++ + +V + G++
Sbjct: 804 YSYSLERHVCLGFVHNFSEDTGEE 827
>gi|44662838 aminomethyltransferase [Homo sapiens]
Length = 403
Score = 90.5 bits (223), Expect = 6e-18
Identities = 101/376 (26%), Positives = 167/376 (44%), Gaps = 44/376 (11%)
Query: 488 AGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDS 547
AGW P QYR S + Q ++ D+S + I G D
Sbjct: 53 AGWSLP---------VQYRDSHT---------DSHLHTRQHCSLFDVSHMLQTKILGSDR 94
Query: 548 IRLLDHL----FANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHD 603
++L++ L A + P G +S G + +L V++ S G +++ +G D
Sbjct: 95 VKLMESLVVGDIAELRPNQG--TLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152
Query: 604 LRWIEE---EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK 660
L +++ E G DV ++ + + L L + GP A +VLQ ++DL F+ +
Sbjct: 153 LALMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTSA 208
Query: 661 SLKVSNIPVTAI-RISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALR 719
++V + + R YTGE G E+ +V L AI+ + + G A ++LR
Sbjct: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLR 265
Query: 720 LEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPA--DFIG-KQALKQIKAKGLKRR--LVC 774
LE +G +++ T P+E L + + + A DF G K + Q+K + +RR L+C
Sbjct: 266 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 325
Query: 775 LTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELL 834
P N G +G TSG S S++K++A YVP + S G + VE+
Sbjct: 326 EGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVR 381
Query: 835 GKNYPAVIIQEPLVLT 850
K AV+ + P V T
Sbjct: 382 RKQQMAVVSKMPFVPT 397
>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
sapiens]
Length = 486
Score = 63.5 bits (153), Expect = 8e-10
Identities = 98/451 (21%), Positives = 180/451 (39%), Gaps = 69/451 (15%)
Query: 48 DRAETVIIGGGCVGVSLAYHLAKA----GMKDVVLLEKSEL--TAGSTWHAAGLTTYFHP 101
+ ++ VI+GGG +G+S+AY L K G V+++E+ A + G+ F
Sbjct: 62 EHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVGGICQQFSL 121
Query: 102 GINLKKIHYDS-----IKLYEKLEEETGQVVGFHQPGSIRLATTP-VRVDEFKYQMTRTG 155
N++ + + I Y + + + F+ G + LA+ E ++ R
Sbjct: 122 PENIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLASEKDAAAMESNVKVQRQ- 180
Query: 156 WHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGD-GHIDPYSLTMALAAGARKCGALL- 213
+ L+ P++++ FP +N V Y D G DP+ L L + G L
Sbjct: 181 -EGAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFC 239
Query: 214 -----KYPAPVTSLKARSDGT------------WDVETPQGSMRANRIVNAAGFWAREVG 256
++ + + D D + ++NAAG W+ ++
Sbjct: 240 QGEVTRFVSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAGAWSAQIA 299
Query: 257 KMIG--------LEHPLIPVQ--HQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDG 306
+ G L+ +PV+ +YV + L E P++ D G+Y+ R+
Sbjct: 300 ALAGVGEGPPGTLQGTKLPVEPRKRYVYVWHCPQGPGL--ETPLVADTSGAYFRREGLGS 357
Query: 307 LLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIIN 366
G E+ + + + + F+ D++ H+ VP + + +
Sbjct: 358 NYLGGRSPTEQEEPDPANLE------VDHDFFQ---DKVWPHLAL---RVPAFETLKVQS 405
Query: 367 VVNGPITYSP-DILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDL 424
G Y+ D +VGPH V N + A GF G+G+ A G+G+ +++ +L G F
Sbjct: 406 AWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGR--FQT 463
Query: 425 IELDPNRYGKWTTTQYTEAKARESYGFNNIV 455
I+L P + T Y K +E NNI+
Sbjct: 464 IDLSPFLF----TRFYLGEKIQE----NNII 486
>gi|60499001 pipecolic acid oxidase [Homo sapiens]
Length = 390
Score = 60.1 bits (144), Expect = 9e-09
Identities = 92/402 (22%), Positives = 158/402 (39%), Gaps = 40/402 (9%)
Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSEL--TAGSTWHAAGLTTYFHPGIN 104
KD + ++IG G G AYHLAK K ++LLE+ L + GS+ + + +
Sbjct: 5 KDLWDAIVIGAGIQGCFTAYHLAK-HRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDF 63
Query: 105 LKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLI 164
++ ++ +++ +LE E G + Q G + L E K E +
Sbjct: 64 YTRMMHECYQIWAQLEHEAGTQL-HRQTGLLLLGMK--ENQELKTIQANLSRQRVEHQCL 120
Query: 165 EPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKA 224
E++++ FP + + + GL + G I Y AL R+ G +++ V +
Sbjct: 121 SSEELKQRFPNIRLPRGEVGLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVVEINP 180
Query: 225 RSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKAL 284
T V+T S +A +V AG W ++ + +G+E PL T+
Sbjct: 181 GLLVT--VKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPL----------QTLRINVCY 228
Query: 285 KRELPVLRDLEGSYYLRQERD-------------GLLFGPYESQEKMKVQDSWVTNGVPP 331
RE+ + GSY + Q GL G Y MKV + P
Sbjct: 229 WREM-----VPGSYGVSQAFPCFLWLGLCPHHIYGLPTGEYPG--LMKVSYHHGNHADPE 281
Query: 332 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 391
+D+ + + +P LK + + + T +PD ++ H N
Sbjct: 282 ERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAV-IESCMYTNTPDEQFILDRHPKYDNI 340
Query: 392 WVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 432
+ GF G+G A VGK L + + P +DL +R+
Sbjct: 341 VIGAGFSGHGFKLAPVVGKILYELSMKLTPSYDLAPFRISRF 382
>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/261 (23%), Positives = 100/261 (38%), Gaps = 37/261 (14%)
Query: 30 CGREGEEKPPLSAETQWKDRAET-----VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSEL 84
C E + P S E Q T ++IGGG G A G+K L+E+ +
Sbjct: 45 CISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLK-TALVERDDF 103
Query: 85 TAGSTWHAAGLTTYFHPGINL--KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPV 142
++G++ + T H G+ K I I+ Y ++E + + A P+
Sbjct: 104 SSGTSSRS---TKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPI 160
Query: 143 RVDEFKYQMTRTGWHATE-------------QYLIEPEKIQEMFPLLNMNKVLAGLYNPG 189
+ +K+ W + Y++ + E FP+L +K L G
Sbjct: 161 MLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDK-LVGAIVYY 219
Query: 190 DGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTW-----------DVETPQG- 237
DG + + +A+A A + GA V SL ++D DV T Q
Sbjct: 220 DGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPQTGKVHVSGARCKDVLTGQEF 279
Query: 238 SMRANRIVNAAGFWAREVGKM 258
+RA ++NA G + V KM
Sbjct: 280 DVRAKCVINATGPFTDSVRKM 300
>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/261 (23%), Positives = 100/261 (38%), Gaps = 37/261 (14%)
Query: 30 CGREGEEKPPLSAETQWKDRAET-----VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSEL 84
C E + P S E Q T ++IGGG G A G+K L+E+ +
Sbjct: 45 CISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLK-TALVERDDF 103
Query: 85 TAGSTWHAAGLTTYFHPGINL--KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPV 142
++G++ + T H G+ K I I+ Y ++E + + A P+
Sbjct: 104 SSGTSSRS---TKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPI 160
Query: 143 RVDEFKYQMTRTGWHATE-------------QYLIEPEKIQEMFPLLNMNKVLAGLYNPG 189
+ +K+ W + Y++ + E FP+L +K L G
Sbjct: 161 MLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDK-LVGAIVYY 219
Query: 190 DGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTW-----------DVETPQG- 237
DG + + +A+A A + GA V SL ++D DV T Q
Sbjct: 220 DGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPQTGKVHVSGARCKDVLTGQEF 279
Query: 238 SMRANRIVNAAGFWAREVGKM 258
+RA ++NA G + V KM
Sbjct: 280 DVRAKCVINATGPFTDSVRKM 300
>gi|28559080 spermine oxidase isoform 4 [Homo sapiens]
Length = 532
Score = 32.3 bits (72), Expect = 1.9
Identities = 17/49 (34%), Positives = 25/49 (51%)
Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87
PLS + + + V+IG G G++ A L + G DV +LE S G
Sbjct: 14 PLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGG 62
>gi|28559078 spermine oxidase isoform 3 [Homo sapiens]
Length = 190
Score = 32.3 bits (72), Expect = 1.9
Identities = 17/49 (34%), Positives = 25/49 (51%)
Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87
PLS + + + V+IG G G++ A L + G DV +LE S G
Sbjct: 14 PLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGG 62
>gi|28559076 spermine oxidase isoform 2 [Homo sapiens]
Length = 502
Score = 32.3 bits (72), Expect = 1.9
Identities = 17/49 (34%), Positives = 25/49 (51%)
Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87
PLS + + + V+IG G G++ A L + G DV +LE S G
Sbjct: 14 PLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGG 62
>gi|28559074 spermine oxidase isoform 1 [Homo sapiens]
Length = 555
Score = 32.3 bits (72), Expect = 1.9
Identities = 17/49 (34%), Positives = 25/49 (51%)
Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87
PLS + + + V+IG G G++ A L + G DV +LE S G
Sbjct: 14 PLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGG 62
>gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo
sapiens]
Length = 463
Score = 32.3 bits (72), Expect = 1.9
Identities = 55/271 (20%), Positives = 110/271 (40%), Gaps = 35/271 (12%)
Query: 24 GRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGV--SLAYHLAKAGMKDVVLLEK 81
GRPR +CG SA T D VI+GGG VG+ + A L + VL ++
Sbjct: 32 GRPRPLCGGSR------SASTSSFD---IVIVGGGIVGLASARALILRHPSLSIGVLEKE 82
Query: 82 SELTAGSTWHAAGLT---TYFHP-GINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRL 137
+L T H +G+ Y+ P + K + LYE +++ + + Q G + +
Sbjct: 83 KDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQKG---ISYKQCGKLIV 139
Query: 138 ATTPVRVDEFKYQMTRTGWHATEQY-LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPY 196
A + + + + LI+ E I++ P + L + P G +D
Sbjct: 140 AVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYC---RGLMAIDCPHTGIVDYR 196
Query: 197 SLTMALAAGARKCGALLKYPAPVTSLK-ARSDGTWDVE----------TPQGSMRANRIV 245
+ ++ A ++ G + V ++ A+ + ++ T +R +V
Sbjct: 197 QVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEEIRCQYVV 256
Query: 246 NAAGFWAREVGKMIGL--EHPLIPVQHQYVV 274
AG ++ + ++ G + ++P + Y++
Sbjct: 257 TCAGLYSDRISELSGCTPDPRIVPFRGDYLL 287
>gi|169206326 PREDICTED: hypothetical protein [Homo sapiens]
Length = 189
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/50 (32%), Positives = 24/50 (48%)
Query: 78 LLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVV 127
+++ +TA H LT +H K HYD + YEK E+ GQ +
Sbjct: 115 IMQFRHVTAVEIQHKLELTVVYHQESEKLKQHYDKEEKYEKYGEDKGQEI 164
>gi|169206576 PREDICTED: hypothetical protein [Homo sapiens]
Length = 189
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/50 (32%), Positives = 24/50 (48%)
Query: 78 LLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVV 127
+++ +TA H LT +H K HYD + YEK E+ GQ +
Sbjct: 115 IMQFRHVTAVEIQHKLELTVVYHQESEKLKQHYDKEEKYEKYGEDKGQEI 164
>gi|169205717 PREDICTED: hypothetical protein [Homo sapiens]
Length = 189
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/50 (32%), Positives = 24/50 (48%)
Query: 78 LLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVV 127
+++ +TA H LT +H K HYD + YEK E+ GQ +
Sbjct: 115 IMQFRHVTAVEIQHKLELTVVYHQESEKLKQHYDKEEKYEKYGEDKGQEI 164
>gi|170650615 protoporphyrinogen oxidase [Homo sapiens]
Length = 477
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 53 VIIGGGCVGVSLAYHLAKAGM-KDVVLLEKSELTAG 87
V++GGG G++ +YHL++A VVL+E SE G
Sbjct: 6 VVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 41
>gi|4506001 protoporphyrinogen oxidase [Homo sapiens]
Length = 477
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 53 VIIGGGCVGVSLAYHLAKAGM-KDVVLLEKSELTAG 87
V++GGG G++ +YHL++A VVL+E SE G
Sbjct: 6 VVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 41
>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 31.6 bits (70), Expect = 3.3
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 11/95 (11%)
Query: 714 AMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN--KPADFIG------KQALKQIKA 765
++ + L KA + L N D + + +++K+N P D+I L Q+
Sbjct: 229 SLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVF 288
Query: 766 KGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNT 800
+KR+L+ L DDVDP E++ Y G+ V ++
Sbjct: 289 DPIKRKLIPLNAYEDDVDP---ETLSYAGQYVDDS 320
>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
Length = 803
Score = 31.6 bits (70), Expect = 3.3
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 11/95 (11%)
Query: 714 AMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN--KPADFIG------KQALKQIKA 765
++ + L KA + L N D + + +++K+N P D+I L Q+
Sbjct: 229 SLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVF 288
Query: 766 KGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNT 800
+KR+L+ L DDVDP E++ Y G+ V ++
Sbjct: 289 DPIKRKLIPLNAYEDDVDP---ETLSYAGQYVDDS 320
>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 31.6 bits (70), Expect = 3.3
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 11/95 (11%)
Query: 714 AMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN--KPADFIG------KQALKQIKA 765
++ + L KA + L N D + + +++K+N P D+I L Q+
Sbjct: 229 SLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVF 288
Query: 766 KGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNT 800
+KR+L+ L DDVDP E++ Y G+ V ++
Sbjct: 289 DPIKRKLIPLNAYEDDVDP---ETLSYAGQYVDDS 320
>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
Length = 649
Score = 31.6 bits (70), Expect = 3.3
Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 24 GRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 83
GR + + G E P S + + +IIGGG G++ A A+ G K +VL +
Sbjct: 143 GRLQKLLKMNGPEDLPKSYDY------DLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTP 196
Query: 84 LTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEE 121
G+ W G T + G KK+ + + L + L++
Sbjct: 197 TPLGTRWGLGG--TCVNVGCIPKKLMHQAALLGQALQD 232
>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
Length = 551
Score = 31.6 bits (70), Expect = 3.3
Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 24 GRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 83
GR + + G E P S + + +IIGGG G++ A A+ G K +VL +
Sbjct: 45 GRLQKLLKMNGPEDLPKSYDY------DLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTP 98
Query: 84 LTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEE 121
G+ W G T + G KK+ + + L + L++
Sbjct: 99 TPLGTRWGLGG--TCVNVGCIPKKLMHQAALLGQALQD 134
>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 30.8 bits (68), Expect = 5.7
Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110
+ +IIGGG G++ A A+ G K +VL + G+ W G T + G KK+ +
Sbjct: 14 DLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGG--TCVNVGCIPKKLMH 71
Query: 111 DSIKLYEKLEE 121
+ L + L++
Sbjct: 72 QAALLGQALQD 82
>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 30.8 bits (68), Expect = 5.7
Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110
+ +IIGGG G++ A A+ G K +VL + G+ W G T + G KK+ +
Sbjct: 14 DLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGG--TCVNVGCIPKKLMH 71
Query: 111 DSIKLYEKLEE 121
+ L + L++
Sbjct: 72 QAALLGQALQD 82
>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 30.8 bits (68), Expect = 5.7
Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110
+ +IIGGG G++ A A+ G K +VL + G+ W G T + G KK+ +
Sbjct: 14 DLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGG--TCVNVGCIPKKLMH 71
Query: 111 DSIKLYEKLEE 121
+ L + L++
Sbjct: 72 QAALLGQALQD 82
>gi|224586807 zinc finger protein 181 isoform 2 [Homo sapiens]
Length = 570
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 112 SIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKI 169
+++ EKLE + G V +P + +P +KY + R+ +H ++ L EP+KI
Sbjct: 119 NLEYIEKLEGKHGSQVDHFRPAILTSRESPTADSVYKYNIFRSTFH-SKSTLSEPQKI 175
>gi|224586802 zinc finger protein 181 isoform 1 [Homo sapiens]
Length = 571
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 112 SIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKI 169
+++ EKLE + G V +P + +P +KY + R+ +H ++ L EP+KI
Sbjct: 120 NLEYIEKLEGKHGSQVDHFRPAILTSRESPTADSVYKYNIFRSTFH-SKSTLSEPQKI 176
>gi|197100773 arginyl-tRNA synthetase 2, mitochondrial precursor
[Homo sapiens]
Length = 578
Score = 30.8 bits (68), Expect = 5.7
Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Query: 638 RKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRRE-DSVALYD 696
R++L K + + +D K+ KS S +P I + ++ + +H S + +
Sbjct: 94 RELLTKTVLQQVIEDGSKY-GLKSELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGN 152
Query: 697 AIMNAGQEEG-----IDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 751
I N + G I+ G + M L F+ +G E +NPL+ E +V++NK
Sbjct: 153 FIANLKEALGHQVIRINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKE 212
Query: 752 A 752
A
Sbjct: 213 A 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,866,765
Number of Sequences: 37866
Number of extensions: 1626936
Number of successful extensions: 3130
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3082
Number of HSP's gapped (non-prelim): 40
length of query: 866
length of database: 18,247,518
effective HSP length: 111
effective length of query: 755
effective length of database: 14,044,392
effective search space: 10603515960
effective search space used: 10603515960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.