Search of human proteins with 24762232

Search of human proteins with 24762232

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
         (485 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa...   981   0.0  
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]          611   e-175
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa...   609   e-174
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s...   604   e-173
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s...   602   e-172
gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]          590   e-168
gi|225579097 bruno-like 5, RNA binding protein isoform 2 [Homo s...   565   e-161
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...   542   e-154
gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3 ...   372   e-103
gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1 ...   367   e-101
gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2...   367   e-101
gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4...   367   e-101
gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3 ...   362   e-100
gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2 ...   357   2e-98
gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1 [...   356   2e-98
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]               87   3e-17
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]               87   3e-17
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...    85   1e-16
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4...    84   2e-16
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [...    84   2e-16
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...    83   5e-16
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...    83   5e-16
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ...    82   8e-16
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ...    82   8e-16
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ...    82   8e-16
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ...    82   8e-16
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ...    81   2e-15
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ...    81   2e-15
gi|4506447 RNA binding motif, single stranded interacting protei...    80   3e-15
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                80   5e-15

>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 485

 Score =  981 bits (2536), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 1   MARLTESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKD 60
           MARLTESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKD
Sbjct: 1   MARLTESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKD 60

Query: 61  LKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQ 120
           LKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQ
Sbjct: 61  LKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQ 120

Query: 121 VKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVK 180
           VKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVK
Sbjct: 121 VKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVK 180

Query: 181 FSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLP 240
           FSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLP
Sbjct: 181 FSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLP 240

Query: 241 FSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLH 300
           FSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLH
Sbjct: 241 FSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLH 300

Query: 301 SPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAF 360
           SPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAF
Sbjct: 301 SPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAF 360

Query: 361 SGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMF 420
           SGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMF
Sbjct: 361 SGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMF 420

Query: 421 LPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKD 480
           LPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKD
Sbjct: 421 LPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKD 480

Query: 481 PGHPY 485
           PGHPY
Sbjct: 481 PGHPY 485


>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
          Length = 465

 Score =  611 bits (1576), Expect = e-175
 Identities = 309/468 (66%), Positives = 368/468 (78%), Gaps = 24/468 (5%)

Query: 39  MKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDS 98
           MK+ DAIKLFVGQIPRHL+EKDLKP+FEQFGRI+ELTV+KD YTG+HKGCAFLTYCARDS
Sbjct: 1   MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDS 60

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFG 158
           A+KAQ+ALHEQKTLPGM RPIQVKPADSESRG  DRKLFVGML KQQ++EDV ++F+PFG
Sbjct: 61  ALKAQSALHEQKTLPGMNRPIQVKPADSESRG-EDRKLFVGMLGKQQTDEDVRKMFEPFG 119

Query: 159 VIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKER 218
            IDECTVLRGPDG+SKGCAFVKF +H EAQAAI+ LH S+T+PGASSSLVVKFADT+KER
Sbjct: 120 TIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKER 179

Query: 219 TLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQ 278
            LRRMQQ+  QLG+ +P + L F  YSAY QALMQQQ  +++   +YLSP    +   +Q
Sbjct: 180 GLRRMQQVATQLGMFSP-IALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQ 238

Query: 279 QIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPI-TNGFAGVVPFPGGHPALETV 337
            + A++ NGL ATPI P+SG  +PP +  T V  + A +  NG++ V   P G PA + +
Sbjct: 239 HMAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDAL 298

Query: 338 YANGLVPYPAQSPTV-AETLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLL------- 389
           Y NG+ PYPAQSP    + L  A++G+Q YTA YP AA + +A + PQPP L+       
Sbjct: 299 YPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYP-AAYSLVAPAFPQPPALVAQQPPPP 357

Query: 390 ------------QQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRAT 437
                       QQQQREGP+GCN+FIYHLPQEF D+E+ QMF+PFG++IS+KVF+DRAT
Sbjct: 358 PQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRAT 417

Query: 438 NQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
           NQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 418 NQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 465



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 27/112 (24%), Positives = 46/112 (41%), Gaps = 6/112 (5%)

Query: 18  QPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVL 77
           QP P P      +    Q    +  D   +F+  +P+   + ++  +F  FG +    V 
Sbjct: 353 QPPPPPQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVF 412

Query: 78  KDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLP-GMAR-PIQVK-PADS 126
            D  T   K   F+++   D+   AQ A+        GM R  +Q+K P D+
Sbjct: 413 VDRATNQSKCFGFVSF---DNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDA 461


>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  609 bits (1571), Expect = e-174
 Identities = 317/474 (66%), Positives = 364/474 (76%), Gaps = 38/474 (8%)

Query: 26  SSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMH 85
           S  P  P   P  MKD DAIKLF+GQIPR+LDEKDLKPLFE+FG+IYELTVLKD +TGMH
Sbjct: 37  SHSPGNPSTIP--MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMH 94

Query: 86  KGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGG---------RDRKL 136
           KGCAFLTYC R+SA+KAQ+ALHEQKTLPGM RPIQVKPADSESRGG         +DRKL
Sbjct: 95  KGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKL 154

Query: 137 FVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHG 196
           FVGMLNKQQSE+DV RLF+ FG I+ECT+LRGPDG+SKGCAFVK+SSH EAQAAI+ALHG
Sbjct: 155 FVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHG 214

Query: 197 SQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQT 256
           SQTMPGASSSLVVKFADTDKERT+RRMQQM GQ+G+  P + +PF  Y AYAQALMQQQ 
Sbjct: 215 SQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNP-MAIPFGAYGAYAQALMQQQA 273

Query: 257 TVLST--SGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLV 314
            ++++   G YL+P  AF+   +QQ+ A+++NGL A P+ P SG  +PP +   AVP + 
Sbjct: 274 ALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIP 333

Query: 315 API-TNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYT--AMYP 371
           +PI  NGF G+ P   G PA E V+ANG+ PYPAQSPT A+ L  A++GVQQY   A YP
Sbjct: 334 SPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYP 393

Query: 372 TAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKV 431
            AA   I+ + PQPPP++ QQQREGPEGCNLFIYHLPQEFGD EL QMFLP         
Sbjct: 394 -AAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLP--------- 443

Query: 432 FMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
                      FGFVSFDNPASAQ AIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 444 -----------FGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486


>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 485

 Score =  604 bits (1558), Expect = e-173
 Identities = 315/473 (66%), Positives = 361/473 (76%), Gaps = 37/473 (7%)

Query: 26  SSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMH 85
           S  P  P   P  MKD DAIKLF+GQIPR+LDEKDLKPLFE+FG+IYELTVLKD +TGMH
Sbjct: 37  SHSPGNPSTIP--MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMH 94

Query: 86  KGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGG---------RDRKL 136
           KGCAFLTYC R+SA+KAQ+ALHEQKTLPGM RPIQVKPADSESRGG         +DRKL
Sbjct: 95  KGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKL 154

Query: 137 FVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHG 196
           FVGMLNKQQSE+DV RLF+ FG I+ECT+LRGPDG+SKGCAFVK+SSH EAQAAI+ALHG
Sbjct: 155 FVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHG 214

Query: 197 SQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQT 256
           SQTMPGASSSLVVKFADTDKERT+RRMQQM GQ+G+  P + +PF  Y AYAQA+ QQ  
Sbjct: 215 SQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNP-MAIPFGAYGAYAQAMQQQAA 273

Query: 257 TVLSTS-GSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVA 315
            + S + G YL+P  AF+   +QQ+ A+++NGL A P+ P SG  +PP +   AVP + +
Sbjct: 274 LMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPS 333

Query: 316 PI-TNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYT--AMYPT 372
           PI  NGF G+ P   G PA E V+ANG+ PYPAQSPT A+ L  A++GVQQY   A YP 
Sbjct: 334 PIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYP- 392

Query: 373 AAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVF 432
           AA   I+ + PQPPP++ QQQREGPEGCNLFIYHLPQEFGD EL QMFLP          
Sbjct: 393 AAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLP---------- 442

Query: 433 MDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
                     FGFVSFDNPASAQ AIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 443 ----------FGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 485


>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
           sapiens]
          Length = 484

 Score =  602 bits (1551), Expect = e-172
 Identities = 314/472 (66%), Positives = 359/472 (76%), Gaps = 36/472 (7%)

Query: 26  SSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMH 85
           S  P  P   P  MKD DAIKLF+GQIPR+LDEKDLKPLFE+FG+IYELTVLKD +TGMH
Sbjct: 37  SHSPGNPSTIP--MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMH 94

Query: 86  KGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRD--------RKLF 137
           KGCAFLTYC R+SA+KAQ+ALHEQKTLPGM RPIQVKPADSESRGG          RKLF
Sbjct: 95  KGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLF 154

Query: 138 VGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGS 197
           VGMLNKQQSE+DV RLF+ FG I+ECT+LRGPDG+SKGCAFVK+SSH EAQAAI+ALHGS
Sbjct: 155 VGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGS 214

Query: 198 QTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTT 257
           QTMPGASSSLVVKFADTDKERT+RRMQQM GQ+G+  P + +PF  Y AYAQA+ QQ   
Sbjct: 215 QTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNP-MAIPFGAYGAYAQAMQQQAAL 273

Query: 258 VLSTS-GSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAP 316
           + S + G YL+P  AF+   +QQ+ A+++NGL A P+ P SG  +PP +   AVP + +P
Sbjct: 274 MASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSP 333

Query: 317 I-TNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYT--AMYPTA 373
           I  NGF G+ P   G PA E V+ANG+ PYPAQSPT A+ L  A++GVQQY   A YP A
Sbjct: 334 IGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYP-A 392

Query: 374 AITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFM 433
           A   I+ + PQPPP++ QQQREGPEGCNLFIYHLPQEFGD EL QMFLP           
Sbjct: 393 AYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLP----------- 441

Query: 434 DRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
                    FGFVSFDNPASAQ AIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 442 ---------FGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 484


>gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]
          Length = 481

 Score =  590 bits (1520), Expect = e-168
 Identities = 314/466 (67%), Positives = 350/466 (75%), Gaps = 11/466 (2%)

Query: 22  SPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPY 81
           S VG SG  P    P  MKD DAIKLFVGQIPR LDE+DLKPLFE+FGRIYELTVLKD  
Sbjct: 25  SGVGMSGLNPGPAVP--MKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRL 82

Query: 82  TGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGML 141
           TG+HKGCAFLTYCARDSA+KAQ+ALHEQKTLPGM RPIQVKPA SE RG  DRKLFVGML
Sbjct: 83  TGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRG-EDRKLFVGML 141

Query: 142 NKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMP 201
            KQQ EEDV RLFQPFG I+ECTVLR PDG+SKGCAFVKF S  EAQAAI  LHGS+TM 
Sbjct: 142 GKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMA 201

Query: 202 GASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLST 261
           GASSSLVVK ADTD+ER LRRMQQM G LG   P+  LP     AY  A++Q Q  +L+ 
Sbjct: 202 GASSSLVVKLADTDRERALRRMQQMAGHLGAFHPA-PLPLGACGAYTTAILQHQAALLAA 260

Query: 262 S-GSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPI-TN 319
           + G  L P VA     +Q + A SL    A P+ PA+  +SPP  G   +PGL API  N
Sbjct: 261 AQGPGLGP-VAAVAAQMQHVAAFSL---VAAPLLPAAAANSPPGSGPGTLPGLPAPIGVN 316

Query: 320 GFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYTAMYPTAAITPIA 379
           GF  + P   G P  +T+Y NGL PYPAQSP VA+ L  A++G+  Y A YP+A   P++
Sbjct: 317 GFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGMHHYAAAYPSA-YAPVS 375

Query: 380 HSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQ 439
            + PQ P  L QQQREGPEGCNLFIYHLPQEFGD EL Q FLPFG ++S+KVF+DRATNQ
Sbjct: 376 TAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQ 435

Query: 440 SKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
           SKCFGFVSFDNP SAQ AIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 436 SKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 481


>gi|225579097 bruno-like 5, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 320

 Score =  565 bits (1456), Expect = e-161
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 115 MARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSK 174
           MARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSK
Sbjct: 1   MARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSK 60

Query: 175 GCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILT 234
           GCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILT
Sbjct: 61  GCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILT 120

Query: 235 PSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIA 294
           PSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIA
Sbjct: 121 PSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIA 180

Query: 295 PASGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAE 354
           PASGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAE
Sbjct: 181 PASGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAE 240

Query: 355 TLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREG 396
           TLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREG
Sbjct: 241 TLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREG 282



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 393 QREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPA 452
           +  G     LF+  L ++  + ++ ++F PFG +I     +      SK   FV F +  
Sbjct: 13  ESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFG-VIDECTVLRGPDGSSKGCAFVKFSSHT 71

Query: 453 SAQAAIQAMNGFQ 465
            AQAAI A++G Q
Sbjct: 72  EAQAAIHALHGSQ 84


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score =  542 bits (1396), Expect = e-154
 Identities = 290/465 (62%), Positives = 336/465 (72%), Gaps = 58/465 (12%)

Query: 26  SSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMH 85
           S  P  P   P  MKD DAIKLF+GQIPR+LDEKDLKPLFE+FG+IYELTVLKD +TGMH
Sbjct: 37  SHSPGNPSTIP--MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMH 94

Query: 86  KGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQ 145
           KGCAFLTYC R+SA+KAQ+ALHEQKTLPGM RPIQVKPADSESRG  DRKLFVGMLNKQQ
Sbjct: 95  KGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRG-EDRKLFVGMLNKQQ 153

Query: 146 SEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASS 205
           SE+DV RLF+ FG I+ECT+LRGPDG+SKGCAFVK+SSH EAQAAI+ALHGSQTMPGASS
Sbjct: 154 SEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASS 213

Query: 206 SLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLST--SG 263
           SLVVKFADTDKERT+RRMQQM GQ+G+  P + +PF  Y AYAQALMQQQ  ++++   G
Sbjct: 214 SLVVKFADTDKERTMRRMQQMAGQMGMFNP-MAIPFGAYGAYAQALMQQQAALMASVAQG 272

Query: 264 SYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPI-TNGFA 322
            YL+P  AF+   +QQ+ A+++NGL A P+ P SG  +PP +   AVP + +PI  NGF 
Sbjct: 273 GYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFT 332

Query: 323 GVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYT--AMYPTAAITPIAH 380
           G+ P   G PA E V+ANG+ PYPAQSPT A+ L  A++GVQQY   A YP AA   I+ 
Sbjct: 333 GLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYP-AAYGQISQ 391

Query: 381 SVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQS 440
           + PQPPP++ QQQRE                                             
Sbjct: 392 AFPQPPPMIPQQQRE--------------------------------------------- 406

Query: 441 KCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
              GFVSFDNPASAQ AIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 407 ---GFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 448


>gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3
           [Homo sapiens]
          Length = 508

 Score =  372 bits (956), Expect = e-103
 Identities = 238/536 (44%), Positives = 305/536 (56%), Gaps = 82/536 (15%)

Query: 3   RLTESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLK 62
           R  +S    + ++LL    +    +G      QPD     DAIK+FVGQIPR   EK+LK
Sbjct: 2   RCPKSAVTMRNEELLLSNGTANKMNGALDHSDQPDP----DAIKMFVGQIPRSWSEKELK 57

Query: 63  PLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQ 120
            LFE +G +Y++ VL+D        KGC F+T+  R +A++AQ ALH  KTLPGM  PIQ
Sbjct: 58  ELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQ 117

Query: 121 VKPADSE-SRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFV 179
           +KPADSE S    DRKLF+GM++K+ +E D+  +F PFG I+EC +LRGPDG S+GCAFV
Sbjct: 118 MKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFV 177

Query: 180 KFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQ---------- 229
            FS+   AQ AI A+H SQTM G SS +VVKFADT K++  RR+QQ + Q          
Sbjct: 178 TFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATW 237

Query: 230 -----LGILTPSL--------------------------TLPFSPYSAYAQALMQQQTTV 258
                LG LTP                             L     +  A A    QT+ 
Sbjct: 238 GNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSA 297

Query: 259 LSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPA-SGLHSPPLLGTT-AVPGLVAP 316
            ST+ + LS   +        +GA++     +TP + A + ++S   LGT   + G    
Sbjct: 298 TSTNANPLSTTSS-------ALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVG 350

Query: 317 ITN--GFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYTAMYPTAA 374
           + N    AG+    GG  A  T   NG       +    + L  A+SG+QQY A     A
Sbjct: 351 LNNINALAGMAALNGGLGA--TGLTNG-------TAGTMDALTQAYSGIQQYAA-----A 396

Query: 375 ITPIAHSVPQPPPLLQQQ-----QREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISS 429
             P  +S      LLQQQ     Q+EGPEG NLFIYHLPQEFGD ++ QMF+PFGN+IS+
Sbjct: 397 ALPTLYS----QSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISA 452

Query: 430 KVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
           KVF+D+ TN SKCFGFVS+DNP SAQAAIQAMNGFQIGMKRLKVQLKR K+   PY
Sbjct: 453 KVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 508


>gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1
           [Homo sapiens]
          Length = 490

 Score =  367 bits (943), Expect = e-101
 Identities = 232/498 (46%), Positives = 293/498 (58%), Gaps = 72/498 (14%)

Query: 41  DLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDS 98
           D DAIK+FVGQIPR   EK+LK LFE +G +Y++ VL+D        KGC F+T+  R +
Sbjct: 12  DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 71

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSE-SRGGRDRKLFVGMLNKQQSEEDVLRLFQPF 157
           A++AQ ALH  KTLPGM  PIQ+KPADSE S    DRKLF+GM++K+ +E D+  +F PF
Sbjct: 72  ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 131

Query: 158 GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKE 217
           G I+EC +LRGPDG S+GCAFV FS+   AQ AI A+H SQTM G SS +VVKFADT K+
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 191

Query: 218 RTLRRMQQMVGQ---------------LGILTPSL------------------------- 237
           +  RR+QQ + Q               LG LTP                           
Sbjct: 192 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 251

Query: 238 -TLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPA 296
             L     +  A A    QT+  ST+ + LS   +        +GA++     +TP + A
Sbjct: 252 NALQLQNLATLAAAAAAAQTSATSTNANPLSTTSS-------ALGALTSPVAASTPNSTA 304

Query: 297 -SGLHSPPLLGTT-AVPGLVAPITNGFA-GVVPFPGGHPALET-VYANGLVPYPAQSPTV 352
            + ++S   LGT   + G    + N  A  V     G  AL   + A GL    A +   
Sbjct: 305 GAAMNSLTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNGTAGT--- 361

Query: 353 AETLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQ-----QREGPEGCNLFIYHL 407
            + L  A+SG+QQY A     A  P  +S      LLQQQ     Q+EGPEG NLFIYHL
Sbjct: 362 MDALTQAYSGIQQYAA-----AALPTLYS----QSLLQQQSAAGSQKEGPEGANLFIYHL 412

Query: 408 PQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIG 467
           PQEFGD ++ QMF+PFGN+IS+KVF+D+ TN SKCFGFVS+DNP SAQAAIQAMNGFQIG
Sbjct: 413 PQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIG 472

Query: 468 MKRLKVQLKRPKDPGHPY 485
           MKRLKVQLKR K+   PY
Sbjct: 473 MKRLKVQLKRSKNDSKPY 490



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 5/76 (6%)

Query: 389 LQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATN--QSKCFGFV 446
           L    +  P+   +F+  +P+ + + EL ++F P+G +    V  DR+ N  QSK   FV
Sbjct: 5   LDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFV 64

Query: 447 SFDNPASAQAAIQAMN 462
           +F    + +AA++A N
Sbjct: 65  TF---YTRKAALEAQN 77


>gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2
           [Homo sapiens]
          Length = 521

 Score =  367 bits (943), Expect = e-101
 Identities = 232/498 (46%), Positives = 293/498 (58%), Gaps = 72/498 (14%)

Query: 41  DLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDS 98
           D DAIK+FVGQIPR   EK+LK LFE +G +Y++ VL+D        KGC F+T+  R +
Sbjct: 43  DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 102

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSE-SRGGRDRKLFVGMLNKQQSEEDVLRLFQPF 157
           A++AQ ALH  KTLPGM  PIQ+KPADSE S    DRKLF+GM++K+ +E D+  +F PF
Sbjct: 103 ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 162

Query: 158 GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKE 217
           G I+EC +LRGPDG S+GCAFV FS+   AQ AI A+H SQTM G SS +VVKFADT K+
Sbjct: 163 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 222

Query: 218 RTLRRMQQMVGQ---------------LGILTPSL------------------------- 237
           +  RR+QQ + Q               LG LTP                           
Sbjct: 223 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 282

Query: 238 -TLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPA 296
             L     +  A A    QT+  ST+ + LS   +        +GA++     +TP + A
Sbjct: 283 NALQLQNLATLAAAAAAAQTSATSTNANPLSTTSS-------ALGALTSPVAASTPNSTA 335

Query: 297 -SGLHSPPLLGTT-AVPGLVAPITNGFA-GVVPFPGGHPALET-VYANGLVPYPAQSPTV 352
            + ++S   LGT   + G    + N  A  V     G  AL   + A GL    A +   
Sbjct: 336 GAAMNSLTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNGTAGT--- 392

Query: 353 AETLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQ-----QREGPEGCNLFIYHL 407
            + L  A+SG+QQY A     A  P  +S      LLQQQ     Q+EGPEG NLFIYHL
Sbjct: 393 MDALTQAYSGIQQYAA-----AALPTLYS----QSLLQQQSAAGSQKEGPEGANLFIYHL 443

Query: 408 PQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIG 467
           PQEFGD ++ QMF+PFGN+IS+KVF+D+ TN SKCFGFVS+DNP SAQAAIQAMNGFQIG
Sbjct: 444 PQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIG 503

Query: 468 MKRLKVQLKRPKDPGHPY 485
           MKRLKVQLKR K+   PY
Sbjct: 504 MKRLKVQLKRSKNDSKPY 521



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 5/76 (6%)

Query: 389 LQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATN--QSKCFGFV 446
           L    +  P+   +F+  +P+ + + EL ++F P+G +    V  DR+ N  QSK   FV
Sbjct: 36  LDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFV 95

Query: 447 SFDNPASAQAAIQAMN 462
           +F    + +AA++A N
Sbjct: 96  TF---YTRKAALEAQN 108


>gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4
           [Homo sapiens]
          Length = 488

 Score =  367 bits (941), Expect = e-101
 Identities = 228/496 (45%), Positives = 291/496 (58%), Gaps = 70/496 (14%)

Query: 41  DLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDS 98
           D DAIK+FVGQIPR   EK+LK LFE +G +Y++ VL+D        KGC F+T+  R +
Sbjct: 12  DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 71

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSE-SRGGRDRKLFVGMLNKQQSEEDVLRLFQPF 157
           A++AQ ALH  KTLPGM  PIQ+KPADSE S    DRKLF+GM++K+ +E D+  +F PF
Sbjct: 72  ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 131

Query: 158 GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKE 217
           G I+EC +LRGPDG S+GCAFV FS+   AQ AI A+H SQTM G SS +VVKFADT K+
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 191

Query: 218 RTLRRMQQMVGQ---------------LGILTPSL------------------------- 237
           +  RR+QQ + Q               LG LTP                           
Sbjct: 192 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 251

Query: 238 -TLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPA 296
             L     +  A A    QT+  ST+ + LS   +        +GA++     +TP + A
Sbjct: 252 NALQLQNLATLAAAAAAAQTSATSTNANPLSTTSS-------ALGALTSPVAASTPNSTA 304

Query: 297 -SGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYAN-GLVPYPAQSPTVAE 354
            + ++S   LGT  + GL A  T G   +    G   ++  +    G       +    +
Sbjct: 305 GAAMNSLTSLGT--LQGL-AGATVGLNNINALAGTINSMAALNGGLGATGLTNGTAGTMD 361

Query: 355 TLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQ-----QREGPEGCNLFIYHLPQ 409
            L  A+SG+QQY A     A  P  +S      LLQQQ     Q+EGPEG NLFIYHLPQ
Sbjct: 362 ALTQAYSGIQQYAA-----AALPTLYS----QSLLQQQSAAGSQKEGPEGANLFIYHLPQ 412

Query: 410 EFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMK 469
           EFGD ++ QMF+PFGN+IS+KVF+D+ TN SKCFGFVS+DNP SAQAAIQAMNGFQIGMK
Sbjct: 413 EFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMK 472

Query: 470 RLKVQLKRPKDPGHPY 485
           RLKVQLKR K+   PY
Sbjct: 473 RLKVQLKRSKNDSKPY 488



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 5/76 (6%)

Query: 389 LQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATN--QSKCFGFV 446
           L    +  P+   +F+  +P+ + + EL ++F P+G +    V  DR+ N  QSK   FV
Sbjct: 5   LDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFV 64

Query: 447 SFDNPASAQAAIQAMN 462
           +F    + +AA++A N
Sbjct: 65  TF---YTRKAALEAQN 77


>gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3
           [Homo sapiens]
          Length = 486

 Score =  362 bits (928), Expect = e-100
 Identities = 220/493 (44%), Positives = 287/493 (58%), Gaps = 66/493 (13%)

Query: 41  DLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDS 98
           DLDAIK+FVGQ+PR   EKDL+ LFEQ+G +YE+ VL+D        KGC F+T+  R +
Sbjct: 12  DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKA 71

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSESRGG-RDRKLFVGMLNKQQSEEDVLRLFQPF 157
           A++AQ ALH  K LPGM  PIQ+KPADSE      DRKLF+GM++K+ +E D+  +F  F
Sbjct: 72  ALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSF 131

Query: 158 GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKE 217
           G I+EC +LRGPDG S+GCAFV F++   AQ AI A+H +QTM G SS +VVKFADT K+
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKD 191

Query: 218 RTLRRMQQMVGQ----------LGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLS 267
           +  +RM Q + Q           G L    TL     + Y Q L Q  ++    + S L 
Sbjct: 192 KEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLH 251

Query: 268 PGVAFSPCHIQQIGAVSLNGLPA-----------TPIAPASGLHSPPLLGTTAVPGLVAP 316
           P    +   +Q + A++     A           T  +P S L S     +++    V P
Sbjct: 252 PMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNP 311

Query: 317 ITN-----------------GFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPA 359
           I +                   AG+    GG  +  +  +NG       + +  E L  A
Sbjct: 312 IASLGALQTLAGATAGLNVGSLAGMAALNGGLGS--SGLSNG-------TGSTMEALTQA 362

Query: 360 FSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQ-------QREGPEGCNLFIYHLPQEFG 412
           +SG+QQY      AA  P  ++      LL QQ       Q+EGPEG NLFIYHLPQEFG
Sbjct: 363 YSGIQQY-----AAAALPTLYN----QNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFG 413

Query: 413 DTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLK 472
           D +L QMF+PFGN++S+KVF+D+ TN SKCFGFVS+DNP SAQAAIQ+MNGFQIGMKRLK
Sbjct: 414 DQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLK 473

Query: 473 VQLKRPKDPGHPY 485
           VQLKR K+   PY
Sbjct: 474 VQLKRSKNDSKPY 486



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 13/108 (12%)

Query: 24  VGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG 83
           +G++G +  G  P+G        LF+  +P+   ++DL  +F  FG +    V  D  T 
Sbjct: 388 IGAAGSQKEG--PEGAN------LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTN 439

Query: 84  MHKGCAFLTYCARDSAIKAQTALHEQKTLP-GMAR-PIQVKPADSESR 129
           + K   F++Y   D+ + AQ A+        GM R  +Q+K + ++S+
Sbjct: 440 LSKCFGFVSY---DNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSK 484


>gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2
           [Homo sapiens]
          Length = 483

 Score =  357 bits (915), Expect = 2e-98
 Identities = 215/489 (43%), Positives = 285/489 (58%), Gaps = 61/489 (12%)

Query: 41  DLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDS 98
           DLDAIK+FVGQ+PR   EKDL+ LFEQ+G +YE+ VL+D        KGC F+T+  R +
Sbjct: 12  DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKA 71

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSESRGG-RDRKLFVGMLNKQQSEEDVLRLFQPF 157
           A++AQ ALH  K LPGM  PIQ+KPADSE      DRKLF+GM++K+ +E D+  +F  F
Sbjct: 72  ALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSF 131

Query: 158 GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKE 217
           G I+EC +LRGPDG S+GCAFV F++   AQ AI A+H +QTM G SS +VVKFADT K+
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKD 191

Query: 218 RTLRRM----QQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFS 273
           +  +RM    QQ + Q+   +    L      A    L  Q   +L  + S  +     S
Sbjct: 192 KEQKRMAQQLQQQMQQISAASVWGNL------AGLNTLGPQYLALLQQTASSGNLNTLSS 245

Query: 274 PCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPIT--NGFAGVVPFPGGH 331
              +  + A+ L  L A   A ++  ++P   GT A+    +P++     AG  P     
Sbjct: 246 LHPMGGLNAMQLQNLAALAAAASAAQNTPS--GTNALTTSSSPLSVLTSSAGSSPSSSSS 303

Query: 332 PALETVYANGLVPYPAQSP----------------------------TVAETLHPAFSGV 363
            ++  + + G +   A +                             +  E L  A+SG+
Sbjct: 304 NSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGI 363

Query: 364 QQYTAMYPTAAITPIAHSVPQPPPLLQQQ-------QREGPEGCNLFIYHLPQEFGDTEL 416
           QQY      AA  P  ++      LL QQ       Q+EGPEG NLFIYHLPQEFGD +L
Sbjct: 364 QQY-----AAAALPTLYN----QNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDL 414

Query: 417 TQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLK 476
            QMF+PFGN++S+KVF+D+ TN SKCFGFVS+DNP SAQAAIQ+MNGFQIGMKRLKVQLK
Sbjct: 415 LQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLK 474

Query: 477 RPKDPGHPY 485
           R K+   PY
Sbjct: 475 RSKNDSKPY 483



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 13/108 (12%)

Query: 24  VGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG 83
           +G++G +  G  P+G        LF+  +P+   ++DL  +F  FG +    V  D  T 
Sbjct: 385 IGAAGSQKEG--PEGAN------LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTN 436

Query: 84  MHKGCAFLTYCARDSAIKAQTALHEQKTLP-GMAR-PIQVKPADSESR 129
           + K   F++Y   D+ + AQ A+        GM R  +Q+K + ++S+
Sbjct: 437 LSKCFGFVSY---DNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSK 481


>gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 482

 Score =  356 bits (914), Expect = 2e-98
 Identities = 220/490 (44%), Positives = 289/490 (58%), Gaps = 64/490 (13%)

Query: 41  DLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG--MHKGCAFLTYCARDS 98
           DLDAIK+FVGQ+PR   EKDL+ LFEQ+G +YE+ VL+D        KGC F+T+  R +
Sbjct: 12  DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKA 71

Query: 99  AIKAQTALHEQKTLPGMARPIQVKPADSESRGG-RDRKLFVGMLNKQQSEEDVLRLFQPF 157
           A++AQ ALH  K LPGM  PIQ+KPADSE      DRKLF+GM++K+ +E D+  +F  F
Sbjct: 72  ALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSF 131

Query: 158 GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKE 217
           G I+EC +LRGPDG S+GCAFV F++   AQ AI A+H +QTM G SS +VVKFADT K+
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKD 191

Query: 218 RTLRRM----QQMVGQLGILTPSLTLP-FSPYSAYAQALMQQQTTV--LSTSGSYLSPGV 270
           +  +RM    QQ + Q+   +    L   +       AL+QQ  +   L+T  S L P  
Sbjct: 192 KEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALLQQTASSGNLNTLSS-LHPMG 250

Query: 271 AFSPCHIQQIGAVSLNGLPA-----------TPIAPASGLHSPPLLGTTAVPGLVAPITN 319
             +   +Q + A++     A           T  +P S L S     +++    V PI +
Sbjct: 251 GLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIAS 310

Query: 320 -----------------GFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSG 362
                              AG+    GG  +  +  +NG       + +  E L  A+SG
Sbjct: 311 LGALQTLAGATAGLNVGSLAGMAALNGGLGS--SGLSNG-------TGSTMEALTQAYSG 361

Query: 363 VQQYTAMYPTAAITPIAHSVPQPPPLLQQQ-------QREGPEGCNLFIYHLPQEFGDTE 415
           +QQY      AA  P  ++      LL QQ       Q+EGPEG NLFIYHLPQEFGD +
Sbjct: 362 IQQY-----AAAALPTLYN----QNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQD 412

Query: 416 LTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQL 475
           L QMF+PFGN++S+KVF+D+ TN SKCFGFVS+DNP SAQAAIQ+MNGFQIGMKRLKVQL
Sbjct: 413 LLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQL 472

Query: 476 KRPKDPGHPY 485
           KR K+   PY
Sbjct: 473 KRSKNDSKPY 482



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 13/108 (12%)

Query: 24  VGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTG 83
           +G++G +  G  P+G        LF+  +P+   ++DL  +F  FG +    V  D  T 
Sbjct: 384 IGAAGSQKEG--PEGAN------LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTN 435

Query: 84  MHKGCAFLTYCARDSAIKAQTALHEQKTLP-GMAR-PIQVKPADSESR 129
           + K   F++Y   D+ + AQ A+        GM R  +Q+K + ++S+
Sbjct: 436 LSKCFGFVSY---DNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSK 480


>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
          Length = 367

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 63/211 (29%), Positives = 102/211 (48%), Gaps = 10/211 (4%)

Query: 15  QLLQPRPSPVGS--SGPEPPGGQ---PDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFG 69
           Q+L    S VG   +GP  P G     +G  D     L V  +P+++ + + K LF   G
Sbjct: 4   QILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIG 63

Query: 70  RIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESR 129
            I    +++D  TG   G  F+ Y   + A KA   L+  K      + I+V  A   S 
Sbjct: 64  DIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKL---QTKTIKVSYARPSSA 120

Query: 130 GGRDRKLFVGMLNKQQSEEDVLRLFQPFG-VIDECTVLRGPDGSSKGCAFVKFSSHTEAQ 188
             RD  L+V  L K  S++++ +LF  +G +I    ++    G S+G  F++F    EA+
Sbjct: 121 SIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAE 180

Query: 189 AAIHALHGSQTMPGASSSLVVKFADTDKERT 219
            AI  L+G + + GA+  + VKFA+   ++T
Sbjct: 181 EAIKGLNGQKPL-GAAEPITVKFANNPSQKT 210



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 92/363 (25%), Positives = 147/363 (40%), Gaps = 59/363 (16%)

Query: 136 LFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGP-DGSSKGCAFVKFSSHTEAQAAIHAL 194
           L V  L +  ++++   LF   G I+ C ++R    G S G  FV +S   +A  AI+ L
Sbjct: 41  LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100

Query: 195 HG----------SQTMPGASSSLVVKFADTDKERTL--RRMQQMVGQLGILTPSLTLPFS 242
           +G          S   P ++S        +   +T+  + M+Q+  Q G +  S      
Sbjct: 101 NGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITS------ 154

Query: 243 PYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSP 302
                 + L+ Q T V        S GV F     +     ++ GL              
Sbjct: 155 ------RILVDQVTGV--------SRGVGFIRFDKRIEAEEAIKGLNG----------QK 190

Query: 303 PLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYAN------GLVPYPAQSPTVAETL 356
           PL       G   PIT  FA       G   L  +Y +      G + +  Q   +   L
Sbjct: 191 PL-------GAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLL 243

Query: 357 HPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTEL 416
           + A+ GV+   ++   A  +PIA         +         G  +F+Y+L  E  ++ L
Sbjct: 244 NMAY-GVKSPLSLI--ARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVL 300

Query: 417 TQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLK 476
            Q+F PFG + + KV  D  TN+ K FGFV+  N   A  AI ++NG+++G + L+V  K
Sbjct: 301 WQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFK 360

Query: 477 RPK 479
             K
Sbjct: 361 TSK 363



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 32/92 (34%), Positives = 46/92 (50%)

Query: 387 PLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFV 446
           PLL           NL + +LPQ     E   +F   G+I S K+  D+ T QS  +GFV
Sbjct: 26  PLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFV 85

Query: 447 SFDNPASAQAAIQAMNGFQIGMKRLKVQLKRP 478
           ++ +P  A  AI  +NG ++  K +KV   RP
Sbjct: 86  NYSDPNDADKAINTLNGLKLQTKTIKVSYARP 117



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 20/61 (32%), Positives = 29/61 (47%)

Query: 47  LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
           +FV  +    DE  L  LF  FG +  + V++D  T   KG  F+T    D A  A  +L
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345

Query: 107 H 107
           +
Sbjct: 346 N 346


>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
          Length = 360

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 63/211 (29%), Positives = 102/211 (48%), Gaps = 10/211 (4%)

Query: 15  QLLQPRPSPVGS--SGPEPPGGQ---PDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFG 69
           Q+L    S VG   +GP  P G     +G  D     L V  +P+++ + + K LF   G
Sbjct: 4   QILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIG 63

Query: 70  RIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESR 129
            I    +++D  TG   G  F+ Y   + A KA   L+  K      + I+V  A   S 
Sbjct: 64  DIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKL---QTKTIKVSYARPSSA 120

Query: 130 GGRDRKLFVGMLNKQQSEEDVLRLFQPFG-VIDECTVLRGPDGSSKGCAFVKFSSHTEAQ 188
             RD  L+V  L K  S++++ +LF  +G +I    ++    G S+G  F++F    EA+
Sbjct: 121 SIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAE 180

Query: 189 AAIHALHGSQTMPGASSSLVVKFADTDKERT 219
            AI  L+G + + GA+  + VKFA+   ++T
Sbjct: 181 EAIKGLNGQKPL-GAAEPITVKFANNPSQKT 210



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 91/360 (25%), Positives = 141/360 (39%), Gaps = 60/360 (16%)

Query: 136 LFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGP-DGSSKGCAFVKFSSHTEAQAAIHAL 194
           L V  L +  ++++   LF   G I+ C ++R    G S G  FV +S   +A  AI+ L
Sbjct: 41  LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100

Query: 195 HG----------SQTMPGASSSLVVKFADTDKERTL--RRMQQMVGQLGILTPSLTLPFS 242
           +G          S   P ++S        +   +T+  + M+Q+  Q G +  S      
Sbjct: 101 NGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITS------ 154

Query: 243 PYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSP 302
                 + L+ Q T V        S GV F     +     ++ GL              
Sbjct: 155 ------RILVDQVTGV--------SRGVGFIRFDKRIEAEEAIKGLNG----------QK 190

Query: 303 PLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLH---PA 359
           PL       G   PIT  FA        +P+ +T  A     Y + +   A  LH     
Sbjct: 191 PL-------GAAEPITVKFAN-------NPSQKTGQALLTHLYQSSARRYAGPLHHQTQR 236

Query: 360 FSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQM 419
           F         Y     +PIA         +         G  +F+Y+L  E  ++ L Q+
Sbjct: 237 FRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQL 296

Query: 420 FLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPK 479
           F PFG + + KV  D  TN+ K FGFV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 297 FGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSK 356



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 32/92 (34%), Positives = 46/92 (50%)

Query: 387 PLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFV 446
           PLL           NL + +LPQ     E   +F   G+I S K+  D+ T QS  +GFV
Sbjct: 26  PLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFV 85

Query: 447 SFDNPASAQAAIQAMNGFQIGMKRLKVQLKRP 478
           ++ +P  A  AI  +NG ++  K +KV   RP
Sbjct: 86  NYSDPNDADKAINTLNGLKLQTKTIKVSYARP 117



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 20/61 (32%), Positives = 29/61 (47%)

Query: 47  LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
           +FV  +    DE  L  LF  FG +  + V++D  T   KG  F+T    D A  A  +L
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338

Query: 107 H 107
           +
Sbjct: 339 N 339


>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 69/250 (27%), Positives = 115/250 (46%), Gaps = 21/250 (8%)

Query: 47  LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
           L V  +P+++ +++LK LF   G I    +++D  TG   G  F+ Y     A KA   L
Sbjct: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100

Query: 107 HEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFG-VIDECTV 165
           +  +      + I+V  A   S   RD  L+V  L K  +++++ +LF  +G +I    +
Sbjct: 101 NGLRL---QTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157

Query: 166 LRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQ 225
           +    G S+G  F++F    EA+ AI  L+G Q  PGA+  + VKFA+   ++T + +  
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG-QKPPGATEPITVKFANNPSQKTNQAILS 216

Query: 226 MVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGV-AFSPCHIQ---QIG 281
            + Q            SP   Y   L QQ       +   ++ GV  FSP  I     + 
Sbjct: 217 QLYQ------------SPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLA 264

Query: 282 AVSLNGLPAT 291
            +++ G P T
Sbjct: 265 GINIPGHPGT 274



 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 94/376 (25%), Positives = 152/376 (40%), Gaps = 67/376 (17%)

Query: 123 PADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGP-DGSSKGCAFVKF 181
           P DS +       L V  L +  ++E++  LF   G I+ C ++R    G S G  FV +
Sbjct: 28  PVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNY 87

Query: 182 SSHTEAQAAIHALHG----------SQTMPGASS--SLVVKFADTDKERTLRRMQQMVGQ 229
               +A+ AI+ L+G          S   P ++S     +  +   K  T + ++Q+  Q
Sbjct: 88  IDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQ 147

Query: 230 LGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLP 289
            G +  S            + L+ Q T +        S GV F     +     ++ GL 
Sbjct: 148 YGRIITS------------RILVDQVTGI--------SRGVGFIRFDKRIEAEEAIKGLN 187

Query: 290 ATPIAPASGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYP--- 346
                                PG   PIT  FA           L  +Y +    YP   
Sbjct: 188 GQK-----------------PPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPL 230

Query: 347 ---AQSPTVAETLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLF 403
              AQ   +   L+ A+ GV++++ M      +    ++P  P         G   C +F
Sbjct: 231 AQQAQRFRLDNLLNMAY-GVKRFSPMTIDGMTSLAGINIPGHP---------GTGWC-IF 279

Query: 404 IYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNG 463
           +Y+L  +  ++ L QMF PFG + + KV  D  TN+ K FGFV+  N   A  AI ++NG
Sbjct: 280 VYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 339

Query: 464 FQIGMKRLKVQLKRPK 479
           +++G + L+V  K  K
Sbjct: 340 YRLGDRVLQVSFKTNK 355



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 10/81 (12%)

Query: 37  DGMKDLDAIKL----------FVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHK 86
           DGM  L  I +          FV  +    DE  L  +F  FG +  + V++D  T   K
Sbjct: 258 DGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCK 317

Query: 87  GCAFLTYCARDSAIKAQTALH 107
           G  F+T    D A  A  +L+
Sbjct: 318 GFGFVTMTNYDEAAMAIASLN 338


>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
           [Homo sapiens]
          Length = 532

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 58/195 (29%), Positives = 104/195 (53%), Gaps = 16/195 (8%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G++     ++FVG+IPR L E +L PLFE+ G I++L ++ DP +G ++G
Sbjct: 47  GGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRG 106

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A       +  PG    + +  A++        +LFVG + K +++
Sbjct: 107 YAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANN--------RLFVGSIPKNKTK 158

Query: 148 EDVLRLFQPF--GVIDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHGSQTMPG 202
           E++L  F     G++D   +   PD   K  G  F+++  H + AQA    + G   + G
Sbjct: 159 ENILEEFSKVTEGLVD-VILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWG 217

Query: 203 ASSSLVVKFADTDKE 217
             + + V++AD  +E
Sbjct: 218 --NVVTVEWADPVEE 230



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + FV F++  +A  A+  M
Sbjct: 242 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 293

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG +I  + +++ L +P D
Sbjct: 294 NGKEIEGEEIEIVLAKPPD 312



 Score = 29.3 bits (64), Expect = 8.4
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 32  PGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFL 91
           P  +PD         LFV  +   + E+ L+  F +FG++  +  LKD         AF+
Sbjct: 227 PVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFV 278

Query: 92  TYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESR 129
            +  R +A+KA   ++ ++        +  KP D + +
Sbjct: 279 HFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRK 316


>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
           [Homo sapiens]
          Length = 633

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 58/195 (29%), Positives = 104/195 (53%), Gaps = 16/195 (8%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G++     ++FVG+IPR L E +L PLFE+ G I++L ++ DP +G ++G
Sbjct: 148 GGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRG 207

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A       +  PG    + +  A++        +LFVG + K +++
Sbjct: 208 YAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANN--------RLFVGSIPKNKTK 259

Query: 148 EDVLRLFQPF--GVIDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHGSQTMPG 202
           E++L  F     G++D   +   PD   K  G  F+++  H + AQA    + G   + G
Sbjct: 260 ENILEEFSKVTEGLVD-VILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWG 318

Query: 203 ASSSLVVKFADTDKE 217
             + + V++AD  +E
Sbjct: 319 --NVVTVEWADPVEE 331



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + FV F++  +A  A+  M
Sbjct: 343 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 394

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG +I  + +++ L +P D
Sbjct: 395 NGKEIEGEEIEIVLAKPPD 413



 Score = 29.3 bits (64), Expect = 8.4
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 32  PGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFL 91
           P  +PD         LFV  +   + E+ L+  F +FG++  +  LKD         AF+
Sbjct: 328 PVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFV 379

Query: 92  TYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESR 129
            +  R +A+KA   ++ ++        +  KP D + +
Sbjct: 380 HFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRK 417


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 58/198 (29%), Positives = 104/198 (52%), Gaps = 19/198 (9%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G++     ++FVG+IPR L E +L PLFE+ G I++L ++ DP +G ++G
Sbjct: 47  GGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRG 106

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A       +  PG    + +  A++        +LFVG + K +++
Sbjct: 107 YAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANN--------RLFVGSIPKNKTK 158

Query: 148 EDVLRLFQPF-----GVIDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHGSQT 199
           E++L  F        G++D   +   PD   K  G  F+++  H + AQA    + G   
Sbjct: 159 ENILEEFSKVTGLTEGLVD-VILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVK 217

Query: 200 MPGASSSLVVKFADTDKE 217
           + G  + + V++AD  +E
Sbjct: 218 VWG--NVVTVEWADPVEE 233



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + FV F++  +A  A+  M
Sbjct: 245 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 296

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG +I  + +++ L +P D
Sbjct: 297 NGKEIEGEEIEIVLAKPPD 315



 Score = 29.3 bits (64), Expect = 8.4
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 32  PGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFL 91
           P  +PD         LFV  +   + E+ L+  F +FG++  +  LKD         AF+
Sbjct: 230 PVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFV 281

Query: 92  TYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESR 129
            +  R +A+KA   ++ ++        +  KP D + +
Sbjct: 282 HFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRK 319


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 58/198 (29%), Positives = 104/198 (52%), Gaps = 19/198 (9%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G++     ++FVG+IPR L E +L PLFE+ G I++L ++ DP +G ++G
Sbjct: 148 GGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRG 207

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A       +  PG    + +  A++        +LFVG + K +++
Sbjct: 208 YAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANN--------RLFVGSIPKNKTK 259

Query: 148 EDVLRLFQPF-----GVIDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHGSQT 199
           E++L  F        G++D   +   PD   K  G  F+++  H + AQA    + G   
Sbjct: 260 ENILEEFSKVTGLTEGLVD-VILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVK 318

Query: 200 MPGASSSLVVKFADTDKE 217
           + G  + + V++AD  +E
Sbjct: 319 VWG--NVVTVEWADPVEE 334



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + FV F++  +A  A+  M
Sbjct: 346 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 397

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG +I  + +++ L +P D
Sbjct: 398 NGKEIEGEEIEIVLAKPPD 416



 Score = 29.3 bits (64), Expect = 8.4
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 32  PGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFL 91
           P  +PD         LFV  +   + E+ L+  F +FG++  +  LKD         AF+
Sbjct: 331 PVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFV 382

Query: 92  TYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESR 129
            +  R +A+KA   ++ ++        +  KP D + +
Sbjct: 383 HFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRK 420


>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 6 [Homo sapiens]
          Length = 562

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 12/173 (6%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256

Query: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHG 196
           E +L  F      + +  +   PD   K  G  F+++  H T AQA    + G
Sbjct: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSG 309



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206

Query: 445 FVSFDNPASAQAAIQAMNGFQI 466
           FV+F    +AQ A++  N  +I
Sbjct: 207 FVTFCTKEAAQEAVKLYNNHEI 228



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)

Query: 5   TESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPL 64
           T ++ARR+           VG+     P   PD         LFV  +   + E+ L+  
Sbjct: 298 TAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKA 357

Query: 65  FEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPA 124
           F QFG++  +  LKD         AF+ +  RD A+KA   ++ +         +  KP 
Sbjct: 358 FSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP 409

Query: 125 DSESR 129
           D + +
Sbjct: 410 DQKRK 414



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 340 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG  +  + +++   +P D
Sbjct: 392 NGKDLEGENIEIVFAKPPD 410


>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 2 [Homo sapiens]
          Length = 464

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 12/173 (6%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 47  GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 106

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 107 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 158

Query: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHG 196
           E +L  F      + +  +   PD   K  G  F+++  H T AQA    + G
Sbjct: 159 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSG 211



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 49  PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 108

Query: 445 FVSFDNPASAQAAIQAMNGFQI 466
           FV+F    +AQ A++  N  +I
Sbjct: 109 FVTFCTKEAAQEAVKLYNNHEI 130



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)

Query: 5   TESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPL 64
           T ++ARR+           VG+     P   PD         LFV  +   + E+ L+  
Sbjct: 200 TAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKA 259

Query: 65  FEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPA 124
           F QFG++  +  LKD         AF+ +  RD A+KA   ++ +         +  KP 
Sbjct: 260 FSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP 311

Query: 125 DSESR 129
           D + +
Sbjct: 312 DQKRK 316



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 242 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 293

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG  +  + +++   +P D
Sbjct: 294 NGKDLEGENIEIVFAKPPD 312


>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 5 [Homo sapiens]
          Length = 561

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 12/173 (6%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256

Query: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHG 196
           E +L  F      + +  +   PD   K  G  F+++  H T AQA    + G
Sbjct: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSG 309



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206

Query: 445 FVSFDNPASAQAAIQAMNGFQI 466
           FV+F    +AQ A++  N  +I
Sbjct: 207 FVTFCTKEAAQEAVKLYNNHEI 228



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)

Query: 5   TESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPL 64
           T ++ARR+           VG+     P   PD         LFV  +   + E+ L+  
Sbjct: 298 TAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKA 357

Query: 65  FEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPA 124
           F QFG++  +  LKD         AF+ +  RD A+KA   ++ +         +  KP 
Sbjct: 358 FSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP 409

Query: 125 DSESR 129
           D + +
Sbjct: 410 DQKRK 414



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 340 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG  +  + +++   +P D
Sbjct: 392 NGKDLEGENIEIVFAKPPD 410


>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 1 [Homo sapiens]
          Length = 623

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 12/173 (6%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256

Query: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHG 196
           E +L  F      + +  +   PD   K  G  F+++  H T AQA    + G
Sbjct: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSG 309



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206

Query: 445 FVSFDNPASAQAAIQAMNGFQI 466
           FV+F    +AQ A++  N  +I
Sbjct: 207 FVTFCTKEAAQEAVKLYNNHEI 228



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)

Query: 5   TESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPL 64
           T ++ARR+           VG+     P   PD         LFV  +   + E+ L+  
Sbjct: 298 TAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKA 357

Query: 65  FEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPA 124
           F QFG++  +  LKD         AF+ +  RD A+KA   ++ +         +  KP 
Sbjct: 358 FSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP 409

Query: 125 DSESR 129
           D + +
Sbjct: 410 DQKRK 414



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 340 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG  +  + +++   +P D
Sbjct: 392 NGKDLEGENIEIVFAKPPD 410


>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 3 [Homo sapiens]
          Length = 527

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 50/168 (29%), Positives = 88/168 (52%), Gaps = 12/168 (7%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256

Query: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAI 191
           E +L  F      + +  +   PD   K  G  F+++  H T AQ  +
Sbjct: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQVKV 304



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206

Query: 445 FVSFDNPASAQAAIQAMNGFQI 466
           FV+F    +AQ A++  N  +I
Sbjct: 207 FVTFCTKEAAQEAVKLYNNHEI 228



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 47  LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
           LFV  +   + E+ L+  F QFG++  +  LKD         AF+ +  RD A+KA   +
Sbjct: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356

Query: 107 HEQKTLPGMARPIQVKPADSESR 129
           + +         +  KP D + +
Sbjct: 357 NGKDLEGENIEIVFAKPPDQKRK 379



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG  +  + +++   +P D
Sbjct: 357 NGKDLEGENIEIVFAKPPD 375


>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 4 [Homo sapiens]
          Length = 588

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 50/168 (29%), Positives = 88/168 (52%), Gaps = 12/168 (7%)

Query: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204

Query: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256

Query: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAI 191
           E +L  F      + +  +   PD   K  G  F+++  H T AQ  +
Sbjct: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQVKV 304



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206

Query: 445 FVSFDNPASAQAAIQAMNGFQI 466
           FV+F    +AQ A++  N  +I
Sbjct: 207 FVTFCTKEAAQEAVKLYNNHEI 228



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 47  LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
           LFV  +   + E+ L+  F QFG++  +  LKD         AF+ +  RD A+KA   +
Sbjct: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356

Query: 107 HEQKTLPGMARPIQVKPADSESR 129
           + +         +  KP D + +
Sbjct: 357 NGKDLEGENIEIVFAKPPDQKRK 379



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 305 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 356

Query: 462 NGFQIGMKRLKVQLKRPKD 480
           NG  +  + +++   +P D
Sbjct: 357 NGKDLEGENIEIVFAKPPD 375


>gi|4506447 RNA binding motif, single stranded interacting protein 1
           isoform c [Homo sapiens]
          Length = 403

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 82/350 (23%), Positives = 137/350 (39%), Gaps = 69/350 (19%)

Query: 21  PSP-VGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKD 79
           PSP   SS          G   L    L++  +P H  ++DL  L + +G+I     + D
Sbjct: 37  PSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILD 96

Query: 80  PYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVG 139
             T   KG  F+ + +  +A KA +AL        MA+  +  P +          L++ 
Sbjct: 97  KTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTN----------LYIS 146

Query: 140 MLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGS-- 197
            L     E+++  + +PFG +    +LR   G+S+G  F +  S  + +A I   +G   
Sbjct: 147 NLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206

Query: 198 QTMPGASS---SLVVKFADTDKERTLR--------RMQQMVGQLGI-------------- 232
           +T PG S+    L+ KFAD  +++           R     G+ G+              
Sbjct: 207 KTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEAGMTLTYDPTTAAIQNG 266

Query: 233 ------------------LTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPG----V 270
                             +TP +  P S Y   + + MQ Q  +L   G+ L+P     +
Sbjct: 267 FYPSPYSIATNRMITQTSITPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTM 326

Query: 271 AFSPCHI-----QQIGAVSLNG----LPATPIAPASGLHSPPLLGTTAVP 311
           +  P  +     QQ+  +SL      +PAT     + L     + TTAVP
Sbjct: 327 SLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVP 376



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 30/78 (38%), Positives = 48/78 (61%)

Query: 401 NLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQA 460
           NL+I  LP    D +L ++  P+G I+S+K  +D+ TN+ K +GFV FD+PA+AQ A+ A
Sbjct: 63  NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122

Query: 461 MNGFQIGMKRLKVQLKRP 478
           +    +  +  K Q + P
Sbjct: 123 LKASGVQAQMAKQQEQDP 140



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 3/75 (4%)

Query: 389 LQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSF 448
           + +QQ + P   NL+I +LP    + EL  M  PFG +IS+++  D ++  S+  GF   
Sbjct: 132 MAKQQEQDPT--NLYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARM 188

Query: 449 DNPASAQAAIQAMNG 463
           ++    +A I   NG
Sbjct: 189 ESTEKCEAVIGHFNG 203



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 67/298 (22%), Positives = 110/298 (36%), Gaps = 35/298 (11%)

Query: 124 ADSESRGGRDR----KLFVGMLNKQQSEEDVLRLFQPFG-VIDECTVLRGPDGSSKGCAF 178
           + S S  G D+     L++  L    +++D+++L QP+G ++    +L       KG  F
Sbjct: 48  SSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGF 107

Query: 179 VKFSSHTEAQAAIHALHGSQTMPGAS------------SSLVVKFADTDKERTLRRMQQM 226
           V F S   AQ A+ AL  S      +            S+L +   + + E  L+   Q+
Sbjct: 108 VDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQV 167

Query: 227 VGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLS--PGVAFSP----CHIQQI 280
           +    IL  S         A  ++  + +  +   +G ++   PGV+       C     
Sbjct: 168 ISTR-ILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADG 226

Query: 281 GAVSLNGLPATPIAPASGLHSPPLLGTTAV-PGLVAPITNGFAGVVPFPGGHPALETVYA 339
           G       P   I      H     G T       A I NGF    P P        +  
Sbjct: 227 GQKKRQN-PNKYIPNGRPWHREGEAGMTLTYDPTTAAIQNGF---YPSPYSIATNRMITQ 282

Query: 340 NGLVPYPAQSPTVAETLHPAFSGVQQYTAMYPTAAITP-IAHSVPQPP-----PLLQQ 391
             + PY A   +  +   P++   Q Y   +P A +TP + H++   P     PL QQ
Sbjct: 283 TSITPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQ 340


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 97/392 (24%), Positives = 154/392 (39%), Gaps = 59/392 (15%)

Query: 47  LFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTAL 106
           ++VG +   + E  L  LF Q G +    + KD  TG H+G  F+ + + +    A  A+
Sbjct: 15  VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEED---ADYAI 71

Query: 107 HEQKTLPGMARPIQVKPADSESRG-GRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDEC-T 164
                +    +PI+V  A + ++       +F+G L+ +  E+ +   F  FGVI +   
Sbjct: 72  KIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPK 131

Query: 165 VLRGPD-GSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRM 223
           ++R PD G+SKG AF+ F+S   + AAI A++G       +  + V +A     +  R  
Sbjct: 132 IMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYL---CNRPITVSYAFKKDSKGERHG 188

Query: 224 QQMVGQLGILTPSLTLPFSPYSAYAQA--LMQQQTTVLSTSGSYL----SPGVAFSPCHI 277
                 L    P L+    P+  +A A         V+S+ GS L     P     P  +
Sbjct: 189 SAAERLLAAQNP-LSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPV 247

Query: 278 QQIGAVSLN---GLPATPIAPASGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGG---H 331
              GA+       +P  P+ P +  H PP  GT   PG   P  +G +   PFP G   H
Sbjct: 248 PPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT---PGAGHP-GHGHSHPHPFPPGGMPH 303

Query: 332 PALETVY-----ANGL---------------------VPYPAQSPTVAETLHPAFSGVQQ 365
           P +  +       +GL                     +P+P   P       P F     
Sbjct: 304 PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMG 363

Query: 366 YTAMYPTAAITPIAHSVPQPPPLLQQQQREGP 397
           +    P        H +  PPPL+      GP
Sbjct: 364 HPGPMP-------PHGMRGPPPLMPPHGYTGP 388



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 1/83 (1%)

Query: 399 GCNLFIYHLPQEFGDTELTQMFLPFGNIISS-KVFMDRATNQSKCFGFVSFDNPASAQAA 457
           G N+FI +L  E  +  L   F  FG I+ + K+  D  T  SK + F++F +  ++ AA
Sbjct: 99  GANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAA 158

Query: 458 IQAMNGFQIGMKRLKVQLKRPKD 480
           I+AMNG  +  + + V     KD
Sbjct: 159 IEAMNGQYLCNRPITVSYAFKKD 181



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 21/79 (26%), Positives = 43/79 (54%)

Query: 395 EGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASA 454
           E  +   +++  L ++  +  L ++FL  G ++++ +  DR T Q + +GFV F +   A
Sbjct: 8   ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67

Query: 455 QAAIQAMNGFQIGMKRLKV 473
             AI+ MN  ++  K ++V
Sbjct: 68  DYAIKIMNMIKLYGKPIRV 86


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,354,482
Number of Sequences: 37866
Number of extensions: 1140405
Number of successful extensions: 6795
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 196
Number of HSP's that attempted gapping in prelim test: 5275
Number of HSP's gapped (non-prelim): 1338
length of query: 485
length of database: 18,247,518
effective HSP length: 106
effective length of query: 379
effective length of database: 14,233,722
effective search space: 5394580638
effective search space used: 5394580638
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.