Search of human proteins with 24586686

Search of human proteins with 24586686

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24586686 voltage-dependent calcium channel gamma-8 subunit
[Homo sapiens]
         (425 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H...   863   0.0  
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho...   379   e-105
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho...   342   5e-94
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho...   329   3e-90
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is...   118   9e-27
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso...   110   2e-24
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H...   105   8e-23
gi|55956899 keratin 9 [Homo sapiens]                                   65   1e-10
gi|47132620 keratin 2 [Homo sapiens]                                   64   3e-10
gi|119395750 keratin 1 [Homo sapiens]                                  62   8e-10
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               62   1e-09
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               62   1e-09
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               62   1e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    62   1e-09
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 60   5e-09
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]         59   6e-09
gi|109255251 loricrin [Homo sapiens]                                   59   1e-08
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     58   1e-08
gi|51479192 ring finger protein 1 [Homo sapiens]                       58   2e-08
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]       57   2e-08
gi|226437592 transmembrane protein 114 [Homo sapiens]                  57   2e-08
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    57   4e-08
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    57   4e-08
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    57   4e-08
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    57   4e-08
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    57   4e-08
gi|195972866 keratin 10 [Homo sapiens]                                 56   5e-08
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo...    56   7e-08
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   56   7e-08
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               55   9e-08

>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
           sapiens]
          Length = 425

 Score =  863 bits (2229), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG 60
           MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG
Sbjct: 1   MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG 60

Query: 61  GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY 120
           GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY
Sbjct: 61  GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY 120

Query: 121 LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY 180
           LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY
Sbjct: 121 LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY 180

Query: 181 ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS 240
           ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS
Sbjct: 181 ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS 240

Query: 241 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA 300
           DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA
Sbjct: 241 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA 300

Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG 360
           STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG
Sbjct: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG 360

Query: 361 GASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNR 420
           GASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNR
Sbjct: 361 GASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNR 420

Query: 421 KTTPV 425
           KTTPV
Sbjct: 421 KTTPV 425


>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
           sapiens]
          Length = 327

 Score =  379 bits (973), Expect = e-105
 Identities = 194/307 (63%), Positives = 233/307 (75%), Gaps = 21/307 (6%)

Query: 15  CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
           C++G+Q+LLTT GAFAAF LM IAI TDYWLY+ A ICN TNLT   DDG P R      
Sbjct: 4   CDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTM--DDGPPPR------ 55

Query: 75  EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPIL 134
             +  G LTHSGLWR+CC+EG+ +G C +INHFPED DYDHDS+EYLLR+VRASS+FPIL
Sbjct: 56  --RARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPIL 113

Query: 135 SAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDE 194
           S ILLLLGG+C+ A R+Y  K NI+L AGILFVAAGLSNIIG+IVYIS+N G+P  KRDE
Sbjct: 114 STILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDE 173

Query: 195 EKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGG 254
           +KKNHY+YGWSFYFG LSFI+AE +GVLAVNIYIE+++E   +++ + LKA         
Sbjct: 174 DKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKA--------- 224

Query: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPG-FASTDISMYTLSRDP 313
           S  S   R+PSYR+R RRRSRSSSRS+E SPSRD SP G    G     ++SMYTLSR+P
Sbjct: 225 SSSSPYARMPSYRYR-RRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREP 283

Query: 314 SKGSVAA 320
            K + AA
Sbjct: 284 LKVTTAA 290


>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
           sapiens]
          Length = 323

 Score =  342 bits (876), Expect = 5e-94
 Identities = 180/304 (59%), Positives = 226/304 (74%), Gaps = 29/304 (9%)

Query: 16  EKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASE 75
           ++GVQ+LLTTVGAFAAF LMTIA+ TDYWLY+R  +C T +++               + 
Sbjct: 5   DRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRG-VCKTKSVSEN------------ETS 51

Query: 76  KKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPILS 135
           KK+   +THSGLWR CCLEG  +G+C +I+HFPED DY+ D+AEY LR VRASSIFPILS
Sbjct: 52  KKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILS 111

Query: 136 AILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEE 195
            ILL +GG+C+AAS  YK++ NIIL AGI FV+AGLSNIIG+IVYISANAG+  P + + 
Sbjct: 112 VILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD--PSKSDS 169

Query: 196 KKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSR-SDLLKAGGGAGGSGG 254
           KKN YSYGWSFYFG LSFI+AE++GVLAV+++I+R ++    +R +D L+A         
Sbjct: 170 KKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQA--------- 220

Query: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG-PGGPGFASTDISMYTLSRDP 313
              SAI R+PSYR+RY+RRSRSSSRS+EPS SRDASP G  G     ST+ISMYTLSRDP
Sbjct: 221 ---SAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDP 277

Query: 314 SKGS 317
            K +
Sbjct: 278 LKAA 281


>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
           sapiens]
          Length = 315

 Score =  329 bits (844), Expect = 3e-90
 Identities = 172/301 (57%), Positives = 214/301 (71%), Gaps = 31/301 (10%)

Query: 15  CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
           C++G+Q+L+TTVGAFAAF LMTIA+ TDYWLY+R  +C T + +               +
Sbjct: 4   CDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRG-VCRTKSTS------------DNET 50

Query: 75  EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPIL 134
            +K+   +THSGLWR CCLEG  RGVC KI+HFPED DY+ D+AEYLLR VRASS+FPIL
Sbjct: 51  SRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPIL 110

Query: 135 SAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDE 194
           S  LL  GG+CVAAS  ++S+ N+IL AGI FV+AGLSNIIG+IVYISANAG+PG +   
Sbjct: 111 SVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR--- 167

Query: 195 EKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGG 254
           + K  YSYGWSFYFG  SFI+AE++GV+AV+IYIE+ ++   +S S+ LK          
Sbjct: 168 DSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLK---------- 217

Query: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPS 314
              S   RLP YR+R+RR  RSSSRS+EP  SRD SP   G     STDISM+TLSRDPS
Sbjct: 218 --KSTFARLPPYRYRFRR--RSSSRSTEPR-SRDLSPISKGFHTIPSTDISMFTLSRDPS 272

Query: 315 K 315
           K
Sbjct: 273 K 273


>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
           isoform a [Homo sapiens]
          Length = 275

 Score =  118 bits (296), Expect = 9e-27
 Identities = 67/218 (30%), Positives = 114/218 (52%), Gaps = 20/218 (9%)

Query: 15  CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
           C +    LL++V A    GL+ IA+STDYWLY    +    N                  
Sbjct: 4   CGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQN------------------ 45

Query: 75  EKKDPGGLTHSGLWRICCLEGLKRGVCVKINH-FPEDTDYDHDSAEYLLRVVRASSIFPI 133
           +  +     HSGLWR+C L G +RG C  I +  P +T    +S   +L+++R+++ FP+
Sbjct: 46  QSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPL 105

Query: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192
           +S   + +G +      +   +  +   +GI F+ +GLS ++G+++YIS+ N       +
Sbjct: 106 VSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165

Query: 193 DEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIER 230
           D E   +Y YGWSF F  +SF+L E  GV++V ++++R
Sbjct: 166 DAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203


>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
           isoform b [Homo sapiens]
          Length = 296

 Score =  110 bits (276), Expect = 2e-24
 Identities = 64/206 (31%), Positives = 105/206 (50%), Gaps = 20/206 (9%)

Query: 15  CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
           C +    LL++V A    GL+ IA+STDYWLY    +    N                  
Sbjct: 4   CGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQN------------------ 45

Query: 75  EKKDPGGLTHSGLWRICCLEGLKRGVCVKINH-FPEDTDYDHDSAEYLLRVVRASSIFPI 133
           +  +     HSGLWR+C L G +RG C  I +  P +T    +S   +L+++R+++ FP+
Sbjct: 46  QSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPL 105

Query: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192
           +S   + +G +      +   +  +   +GI F+ +GLS ++G+++YIS+ N       +
Sbjct: 106 VSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165

Query: 193 DEEKKNHYSYGWSFYFGGLSFILAEV 218
           D E   +Y YGWSF F  +SF+L EV
Sbjct: 166 DAETYFNYKYGWSFAFAAISFLLTEV 191


>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
           sapiens]
          Length = 275

 Score =  105 bits (262), Expect = 8e-23
 Identities = 67/221 (30%), Positives = 108/221 (48%), Gaps = 20/221 (9%)

Query: 15  CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
           C      LL++V       L+ IA+STDYWLY               ++GT         
Sbjct: 4   CSSRALTLLSSVFGACGLLLVGIAVSTDYWLYM--------------EEGTVLPQNQTTE 49

Query: 75  EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPE-DTDYDHDSAEYLLRVVRASSIFPI 133
            K       H+GLWR+C   G ++G CV   +F E + +   ++ E +L+ VR ++ FP+
Sbjct: 50  VKM----ALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPM 105

Query: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192
           +S  L+    V      +   +  +   +GI F+ +GLS ++G+++YIS+ N        
Sbjct: 106 VSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPS 165

Query: 193 DEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSRE 233
             E+  HY YGWSF F   SF+L E  GV++V ++ +R  E
Sbjct: 166 SSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 49/133 (36%), Positives = 55/133 (41%), Gaps = 7/133 (5%)

Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPS-----PSRDASPG 292
           S S L ++GGG GG  GSG S  +R    RF          R S  S      SR    G
Sbjct: 7   SSSYLSRSGGGGGGGLGSGGS--IRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64

Query: 293 GPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGG 352
           G G  G++    S    S     G    G  G GG  GG   + GG  GG GGG GGG G
Sbjct: 65  GGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFG 124

Query: 353 AGAERDRGGASGF 365
            G     GG  GF
Sbjct: 125 GGYGSGFGGFGGF 137



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 50/141 (35%), Positives = 59/141 (41%), Gaps = 27/141 (19%)

Query: 247 GGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISM 306
           GG GGSGGS              Y R SR  S  S        S GG GG G  S   S 
Sbjct: 476 GGRGGSGGS--------------YGRGSRGGSGGSY---GGGGSGGGYGG-GSGSRGGSG 517

Query: 307 YTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAG---------GGGGGGGGAGAER 357
            +       G  + G  G G GGG + G+ GG +GG+G         GGG GGG  G   
Sbjct: 518 GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSG 577

Query: 358 DRGGASGFLTLHNAFPKEAGG 378
            RGG+ G     + F  E+GG
Sbjct: 578 SRGGSGGSHGGGSGFGGESGG 598



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 10/109 (9%)

Query: 261 LRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAA 320
           +RL      Y           E S +     GG GG G      S    SR  S GS   
Sbjct: 445 MRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGG-----SYGRGSRGGSGGSYGG 499

Query: 321 GLAGAGGGGG-----GAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
           G +G G GGG     G+ G++GG +G  GG GGG GG       GG+ G
Sbjct: 500 GGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGG 548



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 40/127 (31%), Positives = 50/127 (39%), Gaps = 12/127 (9%)

Query: 247 GGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP---GFASTD 303
           GG+GGS G G S       Y      R  S       S S   S GG GG    G +   
Sbjct: 491 GGSGGSYGGGGSG----GGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGS 546

Query: 304 ISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGG-----GGGGAGAERD 358
              ++     + G  +    G+GGG GG  G+ GG+ G  GGG G     GG   G E  
Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606

Query: 359 RGGASGF 365
            G   G+
Sbjct: 607 SGSGGGY 613



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/123 (32%), Positives = 48/123 (39%), Gaps = 15/123 (12%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGG--PGFASTD 303
           GGG+G  GGSG S         +     S   S       S     GG GG   G +  +
Sbjct: 507 GGGSGSRGGSGGS---------YGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGN 557

Query: 304 ISMYTLSRDPSKGSVAAGLAGAGGGGG--GAVGAFGGAAGGAGGGGGGGGGAGAERDRGG 361
               + S   S G    G    GG GG  G    FGG +GG+ GGG    G+G     GG
Sbjct: 558 YGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG--GYGG 615

Query: 362 ASG 364
            SG
Sbjct: 616 GSG 618



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 35/120 (29%), Positives = 41/120 (34%), Gaps = 48/120 (40%)

Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304
           +GGG GG  G G S                                 GG GG        
Sbjct: 530 SGGGYGGGSGGGHS---------------------------------GGSGG-------- 548

Query: 305 SMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
                      G    G +G+GGG GG  G   G+ GG+GG  GGG G G E   GG+ G
Sbjct: 549 -----GHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE--SGGSYG 601



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 29/68 (42%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 314 SKGSVAAGLAGAGGGGGG-AVGAFGGAAGGAGGGG-GGGGGAGAERDRGGASGFLTLHNA 371
           S G+   GL G GG GG    G+ GG+ G  GGGG GGG G G+   RGG+ G     + 
Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGS-GSRGGSGGSYGGGSG 525

Query: 372 FPKEAGGG 379
               +GGG
Sbjct: 526 SGGGSGGG 533


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 50/136 (36%), Positives = 62/136 (45%), Gaps = 20/136 (14%)

Query: 231 SREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDAS 290
           S +  C+SR    + GGG G  G S  SA++            SR S+ S          
Sbjct: 2   SCQISCKSRG---RGGGGGGFRGFSSGSAVVS---------GGSRRSTSSFSCLSRHGGG 49

Query: 291 PGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG-GAVGAFGGAAGGAGGGGGG 349
            GG GG GF S   S+  L      G+ +  ++ AGGGGG GA G FGG  GG GGG   
Sbjct: 50  GGGFGGGGFGSR--SLVGLG-----GTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSF 102

Query: 350 GGGAGAERDRGGASGF 365
           GGG+G      G  GF
Sbjct: 103 GGGSGFSGGGFGGGGF 118



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 42/133 (31%), Positives = 54/133 (40%), Gaps = 29/133 (21%)

Query: 250 GGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTL 309
           GGSGG G S+                SS  SS  S  R +   G  G G           
Sbjct: 519 GGSGGRGSSS------------GGGYSSGSSSYGSGGRQSGSRGGSGGG----------- 555

Query: 310 SRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLH 369
                 GS++ G  G+GGG GG  G+ GG+ GG+  GGG G G G     GG+ G  +  
Sbjct: 556 ------GSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG 609

Query: 370 NAFPKEAGGGVTV 382
             +    GG  +V
Sbjct: 610 GGYGSGGGGSSSV 622



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 29/78 (37%), Positives = 35/78 (44%), Gaps = 5/78 (6%)

Query: 289 ASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGG- 347
           A+ GG GG G +S+     + S     G   +G  G  GGGG   G  GG   G G GG 
Sbjct: 516 AAFGGSGGRG-SSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISG--GGYGSGGGSGGR 572

Query: 348 -GGGGGAGAERDRGGASG 364
            G GGG+      GG  G
Sbjct: 573 YGSGGGSKGGSISGGGYG 590



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 34/120 (28%), Positives = 40/120 (33%), Gaps = 51/120 (42%)

Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304
           +GGG G  GGSG                              R  S GG           
Sbjct: 559 SGGGYGSGGGSG-----------------------------GRYGSGGG----------- 578

Query: 305 SMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
                    SKG   +G  G  G GGG   + GG+ GG+  GGG G G G      G+SG
Sbjct: 579 ---------SKGGSISG--GGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSG 627



 Score = 35.8 bits (81), Expect = 0.076
 Identities = 27/76 (35%), Positives = 33/76 (43%), Gaps = 20/76 (26%)

Query: 308 TLSRDPSKGSVAAGLAGAGG-----GGG--------GAVGAFGGAAGGAGGGG------- 347
           T S   S  +  A   G+GG     GGG        G+ G   G+ GG+GGGG       
Sbjct: 504 TSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGY 563

Query: 348 GGGGGAGAERDRGGAS 363
           G GGG+G     GG S
Sbjct: 564 GSGGGSGGRYGSGGGS 579



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 20/73 (27%)

Query: 324 GAGGGGGGAVGAFGGAA---GGA--------------GGGGGGGGGAGAERDRGGASGFL 366
           G GGGGGG  G   G+A   GG+              GGGGG GGG    R   G  G  
Sbjct: 11  GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTK 70

Query: 367 TLHNAFPKEAGGG 379
           ++  +    AGGG
Sbjct: 71  SISISV---AGGG 80



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 9/72 (12%)

Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGG------GGGGGGG-- 352
           +  ++  T+S + +  +   G  G G   GG   + G ++ G+GG      GG GGGG  
Sbjct: 500 TVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSS-GSSSYGSGGRQSGSRGGSGGGGSI 558

Query: 353 AGAERDRGGASG 364
           +G     GG SG
Sbjct: 559 SGGGYGSGGGSG 570


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/156 (34%), Positives = 68/156 (43%), Gaps = 10/156 (6%)

Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSS-RSSEPSPSRDASPGGPGG 296
           SR    ++G  +GG   SG + I+        Y+RR+ SSS R S     R +S GG GG
Sbjct: 2   SRQFSSRSGYRSGGGFSSGSAGIIN-------YQRRTTSSSTRRSGGGGGRFSSCGGGGG 54

Query: 297 PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAE 356
              A       +L       S++  +A  GG G G  G +GG   G GG GGGG G G  
Sbjct: 55  SFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGG- 113

Query: 357 RDRGGASGFLTLHNAFPKEA-GGGVTVTVTGPPAPP 391
              GG  GF +    F     GGG      GP  PP
Sbjct: 114 IGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPP 149



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 45/128 (35%), Positives = 52/128 (40%), Gaps = 27/128 (21%)

Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP 297
           S S    +GGG+ G GG G                    S  SS  S       GG GG 
Sbjct: 506 STSHTTISGGGSRGGGGGG------------------YGSGGSSYGSGGGSYGSGGGGGG 547

Query: 298 GFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG--GAVGAFGGAAGGAGGGGGGGGGAGA 355
           G  S        S   S GS   G  G+GGGGG  G+ G+   + G  GG GGGGGG+  
Sbjct: 548 GRGSYG------SGGSSYGS-GGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600

Query: 356 ERDRGGAS 363
            R  GG S
Sbjct: 601 GRGSGGGS 608



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 17/95 (17%)

Query: 277 SSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAF 336
           S  +S  + S   S GG GG G+ S   S          GS   G  G+GGGGGG  G++
Sbjct: 504 SVSTSHTTISGGGSRGGGGG-GYGSGGSSY---------GS-GGGSYGSGGGGGGGRGSY 552

Query: 337 G------GAAGGAGGGGGGGGGAGAERDRGGASGF 365
           G      G+ GG+ G GGGGGG G+      + G+
Sbjct: 553 GSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY 587



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 5/79 (6%)

Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG 360
           +  +S+ T     S G    G  G  G GG + G+ GG+ G  GGGGGG G  G+     
Sbjct: 500 NVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSY 559

Query: 361 GASGFLTLHNAFPKEAGGG 379
           G+ G      ++    GGG
Sbjct: 560 GSGG-----GSYGSGGGGG 573



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 43/140 (30%)

Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304
           +GGG+ GSGG G               R S  S  SS  S       GG GG        
Sbjct: 534 SGGGSYGSGGGGGGG------------RGSYGSGGSSYGSGGGSYGSGGGGG-------- 573

Query: 305 SMYTLSRDPSKGSVAAGLAGAG--GGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGA 362
                      GS  +G +  G  GG G   G  GG++GG G GGG  GG+     RG +
Sbjct: 574 ---------GHGSYGSGSSSGGYRGGSG---GGGGGSSGGRGSGGGSSGGSIG--GRGSS 619

Query: 363 SGFLTLHNAFPKEAGGGVTV 382
           SG +       K +GG  +V
Sbjct: 620 SGGV-------KSSGGSSSV 632


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 23/160 (14%)

Query: 274 SRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333
           S SSS ++  + S  +SP    GP  AS+  +++      S  + AA +   GGGGGG  
Sbjct: 23  SASSSGTTTSTSSATSSPAPSIGPP-ASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGG 81

Query: 334 GAFGGAAGGAGGGGGGGGG--------AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVT 385
              GG + G GGGGGGGGG        A A    GG  G ++        AGGGV     
Sbjct: 82  SGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGIS--------AGGGVA---- 129

Query: 386 GPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV 425
              + P  A    S+ +  + +  +++S++++ +    P+
Sbjct: 130 --SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 22/148 (14%)

Query: 276 SSSRSSEPSPSRDASPGGPGGPGF--------ASTDISMYTLSRDPSKGSVAAGLAGAGG 327
           +SS +S P+PS    P    GP          A+   +  T +     G  + G  G+ G
Sbjct: 33  TSSATSSPAPS--IGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSG 90

Query: 328 GGGGAVGAFGGA------------AGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375
            GGG  G  GG+            +GG GGG   GGG  +      ++G  +  ++    
Sbjct: 91  NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150

Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAP 403
           +    + + +     P P  P  S P+P
Sbjct: 151 SSSSSSSSSSSSSCGPLPGKPVYSTPSP 178



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 52/159 (32%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GGG GGSGG G S+                              + GG GG G  S    
Sbjct: 76  GGGGGGSGGGGGSS-----------------------------GNGGGGGGGGGGSN--- 103

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365
                      ++AA  A  G GGGG         GG   GGG           G +S  
Sbjct: 104 --------CNPNLAA--ASNGSGGGG---------GGISAGGGVASSTPINASTGSSSSS 144

Query: 366 LTLHNAFPKEAGGGVTVTVTGP-PAPPAPAPPAPSAPAP 403
            +  ++    +    + +  GP P  P  + P+P    P
Sbjct: 145 SSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTP 183


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 23/160 (14%)

Query: 274 SRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333
           S SSS ++  + S  +SP    GP  AS+  +++      S  + AA +   GGGGGG  
Sbjct: 23  SASSSGTTTSTSSATSSPAPSIGPP-ASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGG 81

Query: 334 GAFGGAAGGAGGGGGGGGG--------AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVT 385
              GG + G GGGGGGGGG        A A    GG  G ++        AGGGV     
Sbjct: 82  SGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGIS--------AGGGVA---- 129

Query: 386 GPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV 425
              + P  A    S+ +  + +  +++S++++ +    P+
Sbjct: 130 --SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 22/148 (14%)

Query: 276 SSSRSSEPSPSRDASPGGPGGPGF--------ASTDISMYTLSRDPSKGSVAAGLAGAGG 327
           +SS +S P+PS    P    GP          A+   +  T +     G  + G  G+ G
Sbjct: 33  TSSATSSPAPS--IGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSG 90

Query: 328 GGGGAVGAFGGA------------AGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375
            GGG  G  GG+            +GG GGG   GGG  +      ++G  +  ++    
Sbjct: 91  NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150

Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAP 403
           +    + + +     P P  P  S P+P
Sbjct: 151 SSSSSSSSSSSSSCGPLPGKPVYSTPSP 178



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 52/159 (32%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GGG GGSGG G S+                              + GG GG G  S    
Sbjct: 76  GGGGGGSGGGGGSS-----------------------------GNGGGGGGGGGGSN--- 103

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365
                      ++AA  A  G GGGG         GG   GGG           G +S  
Sbjct: 104 --------CNPNLAA--ASNGSGGGG---------GGISAGGGVASSTPINASTGSSSSS 144

Query: 366 LTLHNAFPKEAGGGVTVTVTGP-PAPPAPAPPAPSAPAP 403
            +  ++    +    + +  GP P  P  + P+P    P
Sbjct: 145 SSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTP 183


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 23/160 (14%)

Query: 274 SRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333
           S SSS ++  + S  +SP    GP  AS+  +++      S  + AA +   GGGGGG  
Sbjct: 23  SASSSGTTTSTSSATSSPAPSIGPP-ASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGG 81

Query: 334 GAFGGAAGGAGGGGGGGGG--------AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVT 385
              GG + G GGGGGGGGG        A A    GG  G ++        AGGGV     
Sbjct: 82  SGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGIS--------AGGGVA---- 129

Query: 386 GPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV 425
              + P  A    S+ +  + +  +++S++++ +    P+
Sbjct: 130 --SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 22/148 (14%)

Query: 276 SSSRSSEPSPSRDASPGGPGGPGF--------ASTDISMYTLSRDPSKGSVAAGLAGAGG 327
           +SS +S P+PS    P    GP          A+   +  T +     G  + G  G+ G
Sbjct: 33  TSSATSSPAPS--IGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSG 90

Query: 328 GGGGAVGAFGGA------------AGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375
            GGG  G  GG+            +GG GGG   GGG  +      ++G  +  ++    
Sbjct: 91  NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150

Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAP 403
           +    + + +     P P  P  S P+P
Sbjct: 151 SSSSSSSSSSSSSCGPLPGKPVYSTPSP 178



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 52/159 (32%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GGG GGSGG G S+                              + GG GG G  S    
Sbjct: 76  GGGGGGSGGGGGSS-----------------------------GNGGGGGGGGGGSN--- 103

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365
                      ++AA  A  G GGGG         GG   GGG           G +S  
Sbjct: 104 --------CNPNLAA--ASNGSGGGG---------GGISAGGGVASSTPINASTGSSSSS 144

Query: 366 LTLHNAFPKEAGGGVTVTVTGP-PAPPAPAPPAPSAPAP 403
            +  ++    +    + +  GP P  P  + P+P    P
Sbjct: 145 SSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTP 183


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 67/262 (25%), Positives = 94/262 (35%), Gaps = 67/262 (25%)

Query: 214 ILAEVIGVLAVNIYIERSREAHCQSRSDLLKAG-----------GGAGGSGGSGPSAILR 262
           ++++++G L   +    +   H   R+  ++A            G   G+ G+GP+A   
Sbjct: 21  VVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE 80

Query: 263 -------LPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA---STDISMYTLSRD 312
                   P    R R       R   PSP R   P GP  P        + S  + +  
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV 140

Query: 313 PSKGSVAAGLAGAGGG-----GGGAVGAFGGAAGGAGGGGGGG------GGAGAERDRGG 361
           P+  +VAAG   A  G     G  A+ A  G   G G G G G       G GA +   G
Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200

Query: 362 ASGFLTLHNA-----------------FPKEAGGGVTVTV------TGPPAPPAPAPPA- 397
           ++  L  H+A                  PK A  G  +          PPAP AP+PPA 
Sbjct: 201 SAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA 260

Query: 398 -----------PSAPAPGTLAK 408
                      P  PAP TLA+
Sbjct: 261 PAPAAPAAAPPPPPPAPATLAR 282



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 42/145 (28%), Positives = 58/145 (40%), Gaps = 6/145 (4%)

Query: 283 PSPSRDASPGG-PGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAG 341
           P+P+  A P G P GP  A+  +     +++      A   A A GG  G  G  G  A 
Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334

Query: 342 GAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAP 401
            A    G    +     +       TL  + P      + +  T   A P+PA   P  P
Sbjct: 335 AAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP--P 392

Query: 402 APGT---LAKEAAASNTNTLNRKTT 423
           APGT   L K AA + T +L+R  T
Sbjct: 393 APGTPTGLPKGAAGAVTQSLSRTPT 417


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 53/174 (30%), Positives = 61/174 (35%), Gaps = 32/174 (18%)

Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304
           +G G G  GG G +                 SSS SS  +       G  GG G      
Sbjct: 495 SGNGRGSGGGQGSNG--------------QGSSSHSSGGNQCSGEGQGSRGGQGSNGQGS 540

Query: 305 SMYTLSRDPSKGSVAAGLAGAGGG----------GGGAVGAFGGAAGGAGGGGGGGGGAG 354
                SRD   G   AG  G+GGG          GG   G   G+ GG   GGG G G+G
Sbjct: 541 GGNQCSRD---GQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSG 597

Query: 355 AERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAK 408
              D  G  G      +  K +  G          PP P PP P  PA GT  K
Sbjct: 598 KGSDGDGERG-----KSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGK 646



 Score = 28.9 bits (63), Expect = 9.3
 Identities = 30/107 (28%), Positives = 40/107 (37%), Gaps = 4/107 (3%)

Query: 261 LRLPSYRFRYRRRSRSSS--RSSEPSPSRDASPG-GPGGPGFASTDISMYTLSRDPSKGS 317
           L LP  R   R  S  +S  R   PSP+R   P   P      S+++S         +G+
Sbjct: 414 LHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGN 473

Query: 318 VAAGLAGAGGGGGGAVGAFGGAAGGAGGGGG-GGGGAGAERDRGGAS 363
                   G GG        G+  G G GGG G  G G+     G +
Sbjct: 474 PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 41/172 (23%)

Query: 264 PSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLA 323
           P Y++R R++ +S + +S  S +  + PG                      KG    G  
Sbjct: 124 PDYKYRPRKKVKSGNANSSSSAAASSKPG---------------------EKGDKVGGSG 162

Query: 324 GAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGA-----------ERDRGGASGFLTLHNAF 372
           G G GGGG     GG +  AGGGGGG  G GA            +  GGA G ++  +A 
Sbjct: 163 GGGHGGGG-----GGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAK 217

Query: 373 PKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTP 424
              AGGG      G  A  A A  A        L    AA++ ++L +  TP
Sbjct: 218 LILAGGG----GGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTP 265



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 42/191 (21%), Positives = 70/191 (36%), Gaps = 26/191 (13%)

Query: 242 LLKAGGGAGGSGG-----------SGPSAILRL---PSYRFRYRRRSRSSSRSSEPSPSR 287
           L+ AGGG GG              +G +A+L L     +   Y+ R+ S+S S+  + S 
Sbjct: 218 LILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASA 277

Query: 288 DASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAF--GGAAGGAGG 345
            A+   P G   A   +    L       S   G  GAG      +G +   GA      
Sbjct: 278 SAALAAP-GKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDA 336

Query: 346 GGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGT 405
               G  + A     G S         P +  G  ++    P    AP+  + SA +  +
Sbjct: 337 PSLSGRSSAASSPAAGRS---------PADHRGYASLRAASPAPSSAPSHASSSASSHSS 387

Query: 406 LAKEAAASNTN 416
            +  + +S+++
Sbjct: 388 SSSSSGSSSSD 398



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 36/125 (28%)

Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304
           +GGG  G GG G S+                            +A  GG G  G  +   
Sbjct: 161 SGGGGHGGGGGGGSS----------------------------NAGGGGGGASGGGAN-- 190

Query: 305 SMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGA-ERDRGGAS 363
                S+   K S  + +AG  GGG     A    AGG GGG      A +   ++ GA+
Sbjct: 191 -----SKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAA 245

Query: 364 GFLTL 368
             L L
Sbjct: 246 ALLPL 250


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 44/143 (30%), Positives = 53/143 (37%), Gaps = 34/143 (23%)

Query: 241 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA 300
           D +K  GG GG GGSG                                   GG G  G +
Sbjct: 15  DCVKTSGGGGGGGGSGGGGC----------------------------GFFGGGGSGGGS 46

Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGA----GGGGGGGGGAGAE 356
           S     Y+     S G    G   +GGGGGG +G  GG +GG+    GGGG  GGG+G  
Sbjct: 47  SGSGCGYSGGGGYSGGGCGGG--SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCF 104

Query: 357 RDRGGASGFLTLHNAFPKEAGGG 379
              GG SG  +         G G
Sbjct: 105 SSGGGGSGCFSSGGGGSSGGGSG 127



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 44/151 (29%), Positives = 59/151 (39%), Gaps = 38/151 (25%)

Query: 236 CQSRSDLLKAGGGAGGSG----GSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP 291
           CQS   +   G   GGSG    G G  ++                   S   S     S 
Sbjct: 158 CQSYGGVSSGGSSGGGSGCFSSGGGGGSVC----------------GYSGGGSGCGGGSS 201

Query: 292 GGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAG-------GGGGGAVGAFGGAAG-GA 343
           GG G    +S  ++  + +  PS G  ++G  G+G       GGGGG+ G  GG++G G+
Sbjct: 202 GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGS 261

Query: 344 G----------GGGGGGGGAGAERDRGGASG 364
           G          GGG  GGG G     G  SG
Sbjct: 262 GCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 36/107 (33%), Positives = 42/107 (39%), Gaps = 26/107 (24%)

Query: 283 PSPSRDA---SPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGA---- 335
           P P  D    S GG GG G                 G    G  G GG GGG+ G+    
Sbjct: 10  PQPPVDCVKTSGGGGGGGG----------------SGGGGCGFFGGGGSGGGSSGSGCGY 53

Query: 336 ---FGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGG 379
               G + GG GGG  GGGG G     GG SG    ++     +GGG
Sbjct: 54  SGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGG 100



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 37/119 (31%), Positives = 42/119 (35%), Gaps = 16/119 (13%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GG  GGS GSG             Y      S        S     GG GG G  S    
Sbjct: 40  GGSGGGSSGSGCG-----------YSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSV 88

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
            Y+       G  + G +G    GGG  G F    GG+ GGG G   +G     GG SG
Sbjct: 89  KYS-----GGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSG 142



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 20/116 (17%)

Query: 240 SDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGF 299
           S    +GGG    GGSG                     S     S    +     GG GF
Sbjct: 111 SGCFSSGGGGSSGGGSG-------------------CFSSGGGGSSGGGSGCFSSGGGGF 151

Query: 300 ASTDISMYTLSRDPSKGSVAAGL-AGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAG 354
           +   +   +     S GS   G    + GGGGG+V  + G   G GGG  GG G+G
Sbjct: 152 SGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSG 207



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG------PGGPG 298
           +GGG    GGSG  +     S  F       S   S   S     S GG       GG G
Sbjct: 91  SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150

Query: 299 FASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERD 358
           F+   +         S G V++G  G+ GGG G   + GG  G   G  GGG G G    
Sbjct: 151 FSGQAVQCQ------SYGGVSSG--GSSGGGSGCFSS-GGGGGSVCGYSGGGSGCGGGSS 201

Query: 359 RGGASGFLT 367
            G  SG+++
Sbjct: 202 GGSGSGYVS 210



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 38/146 (26%), Positives = 45/146 (30%), Gaps = 32/146 (21%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GGG GG GG    ++               S    S    S   S GG G   F+S    
Sbjct: 74  GGGIGGCGGGSGGSV-------------KYSGGGGSSGGGSGCFSSGGGGSGCFSSG--- 117

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGG------------GGGGGGGA 353
                   S G      +G GG  GG  G F    GG  G             GG  GG 
Sbjct: 118 ----GGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG 173

Query: 354 GAERDRGGASGFLTLHNAFPKEAGGG 379
                 GG  G +  ++      GGG
Sbjct: 174 SGCFSSGGGGGSVCGYSGGGSGCGGG 199



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 42/145 (28%), Positives = 52/145 (35%), Gaps = 32/145 (22%)

Query: 240 SDLLKAGGGAGGSGGSG--PSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP 297
           S    +GGG    GGSG   S          + +     SS  S    S   S GG GG 
Sbjct: 126 SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG- 184

Query: 298 GFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGA-------------FGGAA--GG 342
                 +  Y      S G    G   +GG G G V +             +GG +  GG
Sbjct: 185 -----SVCGY------SGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233

Query: 343 AGGGGG---GGGGAGAERDRGGASG 364
             GG G    GGG G+    GG+SG
Sbjct: 234 GSGGSGCFSSGGGGGSSGCGGGSSG 258


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 39/113 (34%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 264 PSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSR-DPSKGSVAAGL 322
           PS   ++ +   SS + SE SP+  +       PG  S      + S   P+  + AA  
Sbjct: 405 PSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAA 464

Query: 323 A-----------GAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
           A           G G G GGA G  GG +G  GGGGG GGG G     GG SG
Sbjct: 465 AAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGG--SSGGGSG 515



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 2/88 (2%)

Query: 278 SRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFG 337
           S S+EP  S + SP        A+   +   +S     G   +G AG G GGG   G  G
Sbjct: 442 SPSAEPQSSSNLSPAAAAAAAAAAAAAA--AVSAVHRGGGSGSGGAGGGSGGGSGSGGGG 499

Query: 338 GAAGGAGGGGGGGGGAGAERDRGGASGF 365
           G AGG GGG  GGG   A    G +S F
Sbjct: 500 GGAGGGGGGSSGGGSGTAGGHSGLSSNF 527


>gi|51479192 ring finger protein 1 [Homo sapiens]
          Length = 406

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 47/126 (37%), Positives = 55/126 (43%), Gaps = 24/126 (19%)

Query: 277 SSRSSEPSPSRDASP---GGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333
           + R   P P  D +    GG G PG    D     +S D +  S A G A     GGGA 
Sbjct: 153 AQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGE--DVSSDSAPDS-APGPAPKRPRGGGAG 209

Query: 334 GAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPP-A 392
           G+  G  GG  GG GGG G+    DRGG  G  TL                 GPP+PP A
Sbjct: 210 GSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTL-----------------GPPSPPGA 252

Query: 393 PAPPAP 398
           P+PP P
Sbjct: 253 PSPPEP 258



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 50/173 (28%), Positives = 59/173 (34%), Gaps = 41/173 (23%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP-------- 297
           G G GG+GG G  A     S     R  +        PSP    SP  PGG         
Sbjct: 214 GTGGGGTGGVGGGA----GSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPH 269

Query: 298 ------------------GFASTD-ISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGG 338
                             G A+ D +S Y   R   +          GG GGGA    GG
Sbjct: 270 PLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDT-GG 328

Query: 339 AAGGAGGGGGGGGGAGAERD-----RGGASGFLTLHNAFPKEAGGGVTVTVTG 386
             G  G GGG GGG G E        G +    T++ A     GGG   T+ G
Sbjct: 329 PDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIA----PGGGAFTTLNG 377


>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 62/218 (28%), Positives = 96/218 (44%), Gaps = 23/218 (10%)

Query: 31  AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90
           +F L+  AI TD+W      I +T  L   G       G    S+ +     +HSGLWR 
Sbjct: 19  SFVLLAAAIGTDFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 71

Query: 91  CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149
           C ++      C  + N F  +     +S+  LL +     I   LS IL++ GG+    S
Sbjct: 72  CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127

Query: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203
            + ++   ++L  GILF+   +  + G+ VYI  SA A        EEK    +   S+G
Sbjct: 128 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186

Query: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241
           WS   G +SFI   + G      ++  +RE   + R D
Sbjct: 187 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220


>gi|226437592 transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 62/218 (28%), Positives = 96/218 (44%), Gaps = 23/218 (10%)

Query: 31  AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90
           +F L+  AI TD+W      I +T  L   G       G    S+ +     +HSGLWR 
Sbjct: 19  SFVLLAAAIGTDFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 71

Query: 91  CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149
           C ++      C  + N F  +     +S+  LL +     I   LS IL++ GG+    S
Sbjct: 72  CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127

Query: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203
            + ++   ++L  GILF+   +  + G+ VYI  SA A        EEK    +   S+G
Sbjct: 128 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186

Query: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241
           WS   G +SFI   + G      ++  +RE   + R D
Sbjct: 187 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 31/61 (50%), Positives = 33/61 (54%), Gaps = 1/61 (1%)

Query: 316 GSVAAGLAGAGG-GGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPK 374
           GS AA   GAGG GGGG   A GG  GG GGGGGG  GAG       A+G L   + F  
Sbjct: 204 GSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSD 263

Query: 375 E 375
           E
Sbjct: 264 E 264



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 31/62 (50%), Positives = 33/62 (53%), Gaps = 8/62 (12%)

Query: 319 AAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGG 378
           AAG A A  GG G  G  G A+ G GGGGGGGGG G     GGA     LH   P  A G
Sbjct: 202 AAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGA-----LH---PHHAAG 253

Query: 379 GV 380
           G+
Sbjct: 254 GL 255



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 7/62 (11%)

Query: 320 AGLAGAGGGGGGAVGAFGGAAGG---AGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEA 376
           AG  GA G    + G  GGA GG   + GGGGGGGG G      GA G L  H+A    A
Sbjct: 197 AGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHA----A 252

Query: 377 GG 378
           GG
Sbjct: 253 GG 254



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 55/199 (27%)

Query: 182 SANAGEPGPKRDEEKKNHYS-YGWSFYFG------GLSFILAEVIGVLAVNIY-IERSRE 233
           S +   P P    E+K H   Y W   +        L F   + +  L  N + ++   +
Sbjct: 70  SPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFD 129

Query: 234 AHCQSRSDLLKAGG-GAGGS-GGSGP---------SAILRL--------PSYRFRYRRRS 274
            + +    L  A G GAG S GGSG          SA++          P Y   +   +
Sbjct: 130 GYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAA 189

Query: 275 RSSSRSSEPSP----SRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG 330
                 +  +P    S  AS GG GG G                      G A AGGGGG
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAG--------------------GGGPASAGGGGG 229

Query: 331 GAVGAFGGAAGGAGGGGGG 349
           G     GG  GG   G GG
Sbjct: 230 GG----GGGGGGGAAGAGG 244



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 13/36 (36%), Positives = 21/36 (58%)

Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAA 411
           AGG ++ T    P    P  P+ SAP+PG+ +++ A
Sbjct: 51  AGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKA 86


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 31/61 (50%), Positives = 33/61 (54%), Gaps = 1/61 (1%)

Query: 316 GSVAAGLAGAGG-GGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPK 374
           GS AA   GAGG GGGG   A GG  GG GGGGGG  GAG       A+G L   + F  
Sbjct: 204 GSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSD 263

Query: 375 E 375
           E
Sbjct: 264 E 264



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 31/62 (50%), Positives = 33/62 (53%), Gaps = 8/62 (12%)

Query: 319 AAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGG 378
           AAG A A  GG G  G  G A+ G GGGGGGGGG G     GGA     LH   P  A G
Sbjct: 202 AAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGA-----LH---PHHAAG 253

Query: 379 GV 380
           G+
Sbjct: 254 GL 255



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 7/62 (11%)

Query: 320 AGLAGAGGGGGGAVGAFGGAAGG---AGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEA 376
           AG  GA G    + G  GGA GG   + GGGGGGGG G      GA G L  H+A    A
Sbjct: 197 AGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHA----A 252

Query: 377 GG 378
           GG
Sbjct: 253 GG 254



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 55/199 (27%)

Query: 182 SANAGEPGPKRDEEKKNHYS-YGWSFYFG------GLSFILAEVIGVLAVNIY-IERSRE 233
           S +   P P    E+K H   Y W   +        L F   + +  L  N + ++   +
Sbjct: 70  SPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFD 129

Query: 234 AHCQSRSDLLKAGG-GAGGS-GGSGP---------SAILRL--------PSYRFRYRRRS 274
            + +    L  A G GAG S GGSG          SA++          P Y   +   +
Sbjct: 130 GYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAA 189

Query: 275 RSSSRSSEPSP----SRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG 330
                 +  +P    S  AS GG GG G                      G A AGGGGG
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAG--------------------GGGPASAGGGGG 229

Query: 331 GAVGAFGGAAGGAGGGGGG 349
           G     GG  GG   G GG
Sbjct: 230 GG----GGGGGGGAAGAGG 244



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 13/36 (36%), Positives = 21/36 (58%)

Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAA 411
           AGG ++ T    P    P  P+ SAP+PG+ +++ A
Sbjct: 51  AGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKA 86


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 62/215 (28%), Positives = 80/215 (37%), Gaps = 54/215 (25%)

Query: 253 GGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP-----GGPGGPGF-----AST 302
           GG GP+A+    +Y          S+  +   P   A P     GG   PG      AS 
Sbjct: 162 GGGGPAAVPEFNNYY--------GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213

Query: 303 DISMYTLSRDPSKGSVAA------------GLAGAGGGGGGAVGAFGGAAGGAGGGGGGG 350
             +    S DP + S                  GAGGGGGG  G  GG+ GG GGGG G 
Sbjct: 214 AAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273

Query: 351 GGAG------------AERDRGGASGFLTLHNAF-----PKEAGGGVTVTVTGPPAPPAP 393
           GGAG            A    GG  G+      +     P++ GGG+ +   G  A  A 
Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA--AS 331

Query: 394 APPAPSAPAPGTLAKEAAASN-----TNTLNRKTT 423
              A +  A G   + A  +      T TLN+  T
Sbjct: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 7/156 (4%)

Query: 229 ERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRD 288
           ++ ++   Q +   +      GG+GG  P     +   +    + S +  ++  P P   
Sbjct: 62  QQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121

Query: 289 ASPGGPGG--PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV----GAFGGAAGG 342
           + PG      P         Y      + G+    +A  GGGGG A       + G+A  
Sbjct: 122 SKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP 181

Query: 343 AGGGGGGGGGAGAERDRGGAS-GFLTLHNAFPKEAG 377
           A GG GG  G   ++  G  S G   +H+A    AG
Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 62/215 (28%), Positives = 80/215 (37%), Gaps = 54/215 (25%)

Query: 253 GGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP-----GGPGGPGF-----AST 302
           GG GP+A+    +Y          S+  +   P   A P     GG   PG      AS 
Sbjct: 162 GGGGPAAVPEFNNYY--------GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213

Query: 303 DISMYTLSRDPSKGSVAA------------GLAGAGGGGGGAVGAFGGAAGGAGGGGGGG 350
             +    S DP + S                  GAGGGGGG  G  GG+ GG GGGG G 
Sbjct: 214 AAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273

Query: 351 GGAG------------AERDRGGASGFLTLHNAF-----PKEAGGGVTVTVTGPPAPPAP 393
           GGAG            A    GG  G+      +     P++ GGG+ +   G  A  A 
Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA--AS 331

Query: 394 APPAPSAPAPGTLAKEAAASN-----TNTLNRKTT 423
              A +  A G   + A  +      T TLN+  T
Sbjct: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 7/156 (4%)

Query: 229 ERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRD 288
           ++ ++   Q +   +      GG+GG  P     +   +    + S +  ++  P P   
Sbjct: 62  QQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121

Query: 289 ASPGGPGG--PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV----GAFGGAAGG 342
           + PG      P         Y      + G+    +A  GGGGG A       + G+A  
Sbjct: 122 SKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP 181

Query: 343 AGGGGGGGGGAGAERDRGGAS-GFLTLHNAFPKEAG 377
           A GG GG  G   ++  G  S G   +H+A    AG
Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 62/215 (28%), Positives = 80/215 (37%), Gaps = 54/215 (25%)

Query: 253 GGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP-----GGPGGPGF-----AST 302
           GG GP+A+    +Y          S+  +   P   A P     GG   PG      AS 
Sbjct: 162 GGGGPAAVPEFNNYY--------GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213

Query: 303 DISMYTLSRDPSKGSVAA------------GLAGAGGGGGGAVGAFGGAAGGAGGGGGGG 350
             +    S DP + S                  GAGGGGGG  G  GG+ GG GGGG G 
Sbjct: 214 AAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273

Query: 351 GGAG------------AERDRGGASGFLTLHNAF-----PKEAGGGVTVTVTGPPAPPAP 393
           GGAG            A    GG  G+      +     P++ GGG+ +   G  A  A 
Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA--AS 331

Query: 394 APPAPSAPAPGTLAKEAAASN-----TNTLNRKTT 423
              A +  A G   + A  +      T TLN+  T
Sbjct: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 7/156 (4%)

Query: 229 ERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRD 288
           ++ ++   Q +   +      GG+GG  P     +   +    + S +  ++  P P   
Sbjct: 62  QQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121

Query: 289 ASPGGPGG--PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV----GAFGGAAGG 342
           + PG      P         Y      + G+    +A  GGGGG A       + G+A  
Sbjct: 122 SKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP 181

Query: 343 AGGGGGGGGGAGAERDRGGAS-GFLTLHNAFPKEAG 377
           A GG GG  G   ++  G  S G   +H+A    AG
Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 49/144 (34%), Positives = 59/144 (40%), Gaps = 14/144 (9%)

Query: 231 SREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYR------FRYRRRSRSS-SRSSEP 283
           S + +  SRS     GGG GG GG G  + LR+ S +      F     S  S SR S  
Sbjct: 7   SSKHYSSSRSG---GGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSG 63

Query: 284 SPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGA 343
                 S GG GG G         +        S      G+ GGG    G+FGG + G 
Sbjct: 64  GGCFGGSSGGYGGLG----GFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGG 119

Query: 344 GGGGGGGGGAGAERDRGGASGFLT 367
           GG GGGG G G     GG  G L+
Sbjct: 120 GGFGGGGFGGGFGGGFGGDGGLLS 143



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 40/132 (30%), Positives = 51/132 (38%), Gaps = 16/132 (12%)

Query: 233 EAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPG 292
           E   Q+   LL+  G +GG G  G S       +   Y      SS             G
Sbjct: 443 ENEIQTYRSLLEGEGSSGGGGRGGGS-------FGGGY---GGGSSGGGSSGGGHGGGHG 492

Query: 293 GPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGG 352
           G  G G+          S   S G    G + +GG GG + G +GG + G GGGG GGG 
Sbjct: 493 GSSGGGYGGGS------SGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGS 546

Query: 353 AGAERDRGGASG 364
           +G     GG  G
Sbjct: 547 SGGGSSSGGGYG 558



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 278 SRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGG------ 331
           S S   S SR    GG GG G       + +L    SKGS+  G +  G  GG       
Sbjct: 6   SSSKHYSSSRSGGGGGGGGCGGGG---GVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62

Query: 332 AVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365
             G FGG++GG GG G  G G G+ R   G+S F
Sbjct: 63  GGGCFGGSSGGYGGLG--GFGGGSFRGSYGSSSF 94



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 20/119 (16%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GGG+ G G SG                       SS       +S GG  G G+      
Sbjct: 474 GGGSSGGGSSGGG--------------HGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS-- 517

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
               S     GS + G  G   GGGG     G + GG+  GGG GGG+ +   +  +SG
Sbjct: 518 ----SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 22/64 (34%), Positives = 28/64 (43%)

Query: 316 GSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375
           GS   G  G   GGG + G +GG +   G GG   GG G     GG  G+    +     
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSS 552

Query: 376 AGGG 379
           +GGG
Sbjct: 553 SGGG 556



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 36/119 (30%), Positives = 42/119 (35%), Gaps = 31/119 (26%)

Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305
           GGG GGS G G                   S   SS       +S GG GG         
Sbjct: 488 GGGHGGSSGGGYGG--------------GSSGGGSSGGGYGGGSSSGGHGGS-------- 525

Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
                   S G    G +G GGGG G  G+ GG +   GG GGG    G +    G+ G
Sbjct: 526 --------SSGGYGGGSSGGGGGGYGG-GSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG 575



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 307 YTLSRDPSKGSVAAGLAGAGGGGGGAVGA--FGGAAGGAGGGGGGGGGAGAERDRGGASG 364
           Y+ S+  S      G  G G GGGG V +     + G  GGG   GG +G    RG + G
Sbjct: 5   YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64


>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
           sapiens]
          Length = 217

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 23/218 (10%)

Query: 31  AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90
           +F L+  AI T++W      I +T  L   G       G    S+ +     +HSGLWR 
Sbjct: 13  SFVLLAAAIGTEFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 65

Query: 91  CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149
           C ++      C  + N F  +     +S+  LL +     I   LS IL++ GG+    S
Sbjct: 66  CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 121

Query: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203
            + ++   ++L  GILF+   +  + G+ VYI  SA A        EEK    +   S+G
Sbjct: 122 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 180

Query: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241
           WS   G +SFI   + G      ++  +RE   + R D
Sbjct: 181 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 214


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 17/161 (10%)

Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG---- 293
           +++ +  AG    GS GS   A L+LP+            ++    + S++ S  G    
Sbjct: 718 TKAQVTAAGPQKSGSQGS-VMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLL 776

Query: 294 -PGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGG---AGGGGGG 349
            P G    +T+      + +   GS A+G +GAGGGGGG  G   G+ GG    GGGG  
Sbjct: 777 IPQGAILRATN------NANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTA 830

Query: 350 GGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAP 390
           GGG  +    GG S  LT  +   K+   G    + G P+P
Sbjct: 831 GGGTQSTAGPGGISQHLTYTSYILKQTPQG--TFLVGQPSP 869


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 27/41 (65%), Positives = 28/41 (68%)

Query: 316 GSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAE 356
           G+ A G  GAGGG GG  GA GG AGGAGGGGGGG  A  E
Sbjct: 35  GNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSRAPPE 75



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 25/53 (47%), Positives = 28/53 (52%), Gaps = 4/53 (7%)

Query: 312 DPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364
           D    S+    +G G G GG  GA GG+ GG G GGGG GGAG     GG  G
Sbjct: 21  DSHHRSILLASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGG----GGGGG 69



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 23/40 (57%), Positives = 25/40 (62%), Gaps = 1/40 (2%)

Query: 319 AAGLAGAGGGGGGAVGAFGG-AAGGAGGGGGGGGGAGAER 357
           + G  GAGGGGG   G+ GG  AGG G GG GGGG G  R
Sbjct: 32  SGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSR 71



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 20/41 (48%), Positives = 22/41 (53%)

Query: 319 AAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDR 359
           ++G     GGGGGA G  GG  G  GGG GG GG G    R
Sbjct: 31  SSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSR 71



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 22/41 (53%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 325 AGGGGGGAVGAFGGAAGGAGGG--GGGGGGAGAERDRGGAS 363
           A  GGG   G  GGA GG+GGG   GGGG  GA    GG S
Sbjct: 30  ASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGS 70


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,340,241
Number of Sequences: 37866
Number of extensions: 1285739
Number of successful extensions: 43721
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 811
Number of HSP's successfully gapped in prelim test: 797
Number of HSP's that attempted gapping in prelim test: 15823
Number of HSP's gapped (non-prelim): 12954
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.