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Search of human proteins with 24308350
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308350 hypothetical protein LOC88745 [Homo sapiens]
(259 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308350 hypothetical protein LOC88745 [Homo sapiens] 511 e-145
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 52 5e-07
gi|148746195 trichohyalin [Homo sapiens] 49 3e-06
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 48 7e-06
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 48 7e-06
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 48 7e-06
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 48 1e-05
gi|166706903 guanylate binding protein 1, interferon-inducible, ... 46 3e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 46 3e-05
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 46 3e-05
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 46 3e-05
gi|4758220 XAP-5 protein [Homo sapiens] 45 8e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 45 8e-05
gi|4505257 moesin [Homo sapiens] 43 2e-04
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 42 4e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 42 4e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 42 4e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 42 4e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 42 4e-04
gi|52426743 cisplatin resistance-associated overexpressed protei... 42 4e-04
gi|19923485 cisplatin resistance-associated overexpressed protei... 42 4e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 42 5e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 42 5e-04
gi|226246533 TOX high mobility group box family member 3 isoform... 41 0.001
gi|226054295 TOX high mobility group box family member 3 isoform... 41 0.001
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 41 0.001
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 41 0.001
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 41 0.001
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 40 0.002
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 40 0.002
>gi|24308350 hypothetical protein LOC88745 [Homo sapiens]
Length = 259
Score = 511 bits (1316), Expect = e-145
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 1 MPGANYRAGAGAGAGARRPRGARDREEDGGGLEPAAVARDLLRGTSNMSFEELLELQSQV 60
MPGANYRAGAGAGAGARRPRGARDREEDGGGLEPAAVARDLLRGTSNMSFEELLELQSQV
Sbjct: 1 MPGANYRAGAGAGAGARRPRGARDREEDGGGLEPAAVARDLLRGTSNMSFEELLELQSQV 60
Query: 61 GTKTYKQLVAGNSPKKQASRPPIQNACVADKHRPLEMSAKIRVPFLRQVVPISKKVARDP 120
GTKTYKQLVAGNSPKKQASRPPIQNACVADKHRPLEMSAKIRVPFLRQVVPISKKVARDP
Sbjct: 61 GTKTYKQLVAGNSPKKQASRPPIQNACVADKHRPLEMSAKIRVPFLRQVVPISKKVARDP 120
Query: 121 RFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEM 180
RFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEM
Sbjct: 121 RFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEM 180
Query: 181 AQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLS 240
AQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLS
Sbjct: 181 AQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLS 240
Query: 241 RKRRRNAGKDRRHLPLSKE 259
RKRRRNAGKDRRHLPLSKE
Sbjct: 241 RKRRRNAGKDRRHLPLSKE 259
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 52.0 bits (123), Expect = 5e-07
Identities = 44/211 (20%), Positives = 101/211 (47%), Gaps = 23/211 (10%)
Query: 45 TSNMSFEELLELQSQVGTKTYKQLVAGNSPKKQASRPPIQNACVADKHRPLEMSAKIRVP 104
+S +S ELL LQ Q + +QL+ Q +++ +DK RPL++ + +
Sbjct: 41 SSEVSTVELLHLQQQQALQAARQLLL------QQQTSGLKSPKSSDKQRPLQVPVSVAMM 94
Query: 105 FLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELV----KKQLKKHL 160
+ + P + + +P+ Q + ++++L K+Q + HL
Sbjct: 95 TPQVITPQQMQQILQQQV------LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHL 148
Query: 161 SGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQL 220
+ ++ QQ Q+ +QQ+ QQ+++QQQ+ +Q+++ Q G + ++ +Q+Q
Sbjct: 149 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 208
Query: 221 ALA-------EKFKELKRSKKLENFLSRKRR 244
LA ++ ++++ ++ ++ LS +R+
Sbjct: 209 QLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 239
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.3 bits (116), Expect = 3e-06
Identities = 29/117 (24%), Positives = 67/117 (57%), Gaps = 2/117 (1%)
Query: 145 RAKEKELVKKQLK--KHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQ 202
R +E+E ++++L+ + L E+ E+ +QLL+R E++ + Q+ R+Q+ + ++++ +
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 203 AQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
++ R LK+ ++ +L K +E++R ++ E R +R ++RR L E
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/124 (31%), Positives = 68/124 (54%), Gaps = 15/124 (12%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQ---QELHLALKQERR 200
+R +++E +++LK+ EE E+LQQ L+ +Q Q+ER++Q +E L+QERR
Sbjct: 507 LRREQEERREQRLKRQ---EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 201 AQA----QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR-RRNAGKDRRHLP 255
Q Q+ R LK+ E+R+ ++ +E ++LE L R+ R ++RR
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQE----ERLEQRLKREEVERLEQEERREQR 619
Query: 256 LSKE 259
L +E
Sbjct: 620 LKRE 623
Score = 46.2 bits (108), Expect = 3e-05
Identities = 30/113 (26%), Positives = 64/113 (56%), Gaps = 5/113 (4%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+E+E +++LK+ E+ E+L+Q L+R E + + Q+ER++Q+ ++ERR Q +
Sbjct: 581 REEERRQQRLKR----EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
++ + R+ + + LKR ++ E L ++ +R ++RR L++E
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEE-EERLEQRLKREHEEERREQELAEE 688
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/144 (24%), Positives = 76/144 (52%), Gaps = 14/144 (9%)
Query: 118 RDPRFDDLSGEYNPEVFDKTY-QFLNDIRAKEKELVKKQLKKHLSGEEHEKL---QQLLQ 173
RD +F + + + + D+ + + +R +E+E + ++ L E H K +QLLQ
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ 1471
Query: 174 RMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLK--KSEQRQLALAEKFKELKR 231
E+Q++ +QER ++ L++E++ + Q+ R + + +S++ + E+ ++L R
Sbjct: 1472 EREEQQLHRQERDRK-----FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 232 SKKLENFLSRK---RRRNAGKDRR 252
++ FL + RR+ G+ RR
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRR 1550
Score = 43.9 bits (102), Expect = 1e-04
Identities = 31/115 (26%), Positives = 62/115 (53%), Gaps = 9/115 (7%)
Query: 147 KEKELVKKQLKKHLSGE--EHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
+E+E ++K ++ L E E E+ QQ L+R +Q Q+E +++Q+ +QERR Q +
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+ ++ E+R + ++L+R ++ E ++ RR ++RR L +E
Sbjct: 333 ERREQQLRREQEER------REQQLRREQE-EERREQQLRREQEEERREQQLRRE 380
Score = 43.9 bits (102), Expect = 1e-04
Identities = 33/137 (24%), Positives = 70/137 (51%), Gaps = 15/137 (10%)
Query: 118 RDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQ 177
++ R L + E ++ + + R +++E ++QL++ E+ E+ +Q L+R E+
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR----EQEERREQRLKRQEE 524
Query: 178 QEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKR--SKKL 235
+E QQ + +Q+L ++ERR Q LK+ E+++L + + LKR ++
Sbjct: 525 EERLQQRLRSEQQLRRE-QEERREQ--------LLKREEEKRLEQERREQRLKREQEERR 575
Query: 236 ENFLSRKRRRNAGKDRR 252
+ L R+ R + +R
Sbjct: 576 DQLLKREEERRQQRLKR 592
Score = 43.5 bits (101), Expect = 2e-04
Identities = 31/133 (23%), Positives = 70/133 (52%), Gaps = 8/133 (6%)
Query: 135 DKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQL------LQRMEQQEMAQ--QERK 186
D+ +Q + +++E V ++ ++ L EE ++ ++L L+++E+QE+ + QE +
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 187 QQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRN 246
QQQ+ +Q RR Q ++ ++ +Q + E+ +E + ++ E ++ RR
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354
Query: 247 AGKDRRHLPLSKE 259
++RR L +E
Sbjct: 355 QEEERREQQLRRE 367
Score = 41.6 bits (96), Expect = 7e-04
Identities = 28/119 (23%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R K++E ++Q ++ E+ E+ +Q +R EQQ +QE +++Q+L ++ERR Q
Sbjct: 306 LRRKQEEERREQQEERR--EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD---RRHLPLSKE 259
+ + ++ + R+ + ++L+R ++L +R + ++ RR L +E
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Score = 39.7 bits (91), Expect = 0.003
Identities = 33/113 (29%), Positives = 59/113 (52%), Gaps = 14/113 (12%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
K+K+L +K+ + L GEE EK + R E+++ ++E + QQE L++ER + +Q
Sbjct: 962 KDKKLQQKE--EQLLGEEPEKRR----RQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Query: 207 HRPYFLKK----SEQRQLALAEKFK----ELKRSKKLENFLSRKRRRNAGKDR 251
+ KK E+ QL E+ K E +R + E L ++ + G++R
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Score = 38.9 bits (89), Expect = 0.005
Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 9/110 (8%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +E+E ++QL++ +E E+ +Q L+R +Q QQ R++QQ L +Q+ R + Q
Sbjct: 353 REQEEERREQQLRRE---QEEERREQQLRREQQLRREQQLRREQQ---LRREQQLRRE-Q 405
Query: 205 QGHRPYFLKKSEQ--RQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
Q R L++ +Q R+ L + +E + +K E +R + ++RR
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Score = 38.5 bits (88), Expect = 0.006
Identities = 26/114 (22%), Positives = 58/114 (50%), Gaps = 10/114 (8%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+E+E + LK+ E HE Q +Q++ + + ++++E L L++E R + Q+
Sbjct: 449 REQEERRDWLKREEETERHE------QERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFL-SRKRRRNAGKDRRHLPLSKE 259
++ E+R+ ++ K + ++L+ L S ++ R ++RR L +E
Sbjct: 503 REQQLRREQEERR---EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Score = 38.5 bits (88), Expect = 0.006
Identities = 32/116 (27%), Positives = 65/116 (56%), Gaps = 21/116 (18%)
Query: 147 KEKELVKKQLKKHLSGEEHEKL----QQLLQRMEQQEMAQQER---------KQQQELHL 193
+EK+L++++ ++ +E ++ +QLLQ E+Q + +QER + Q++
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 194 ALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRS-----KKLENFLSRKRR 244
L++E+R + Q+ R FLK E++QL E+ ++L++ ++ E LSR+ R
Sbjct: 1376 FLEEEQRLRRQERERK-FLK--EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Score = 37.0 bits (84), Expect = 0.017
Identities = 30/122 (24%), Positives = 63/122 (51%), Gaps = 7/122 (5%)
Query: 143 DIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQE--MAQQERKQQQELHLALKQERR 200
++R + +E ++Q ++ L E+ + +Q +R EQQE QQER++QQE + R
Sbjct: 285 ELRRERQE--EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 201 AQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD---RRHLPLS 257
+ ++ + ++ E+R+ L + +E +R ++L +R + ++ RR L
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 258 KE 259
+E
Sbjct: 403 RE 404
Score = 37.0 bits (84), Expect = 0.017
Identities = 26/119 (21%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLA--LKQERRA 201
+R +++E ++QL++ +E E+ +Q L+R +++E +Q+ +++Q+L L++E++
Sbjct: 339 LRREQEERREQQLRRE---QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 202 QAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR-RRNAGKDRRHLPLSKE 259
+ +Q R ++ + R+ + ++L+R ++L +R + ++RR L +E
Sbjct: 396 RREQQLR----REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Score = 37.0 bits (84), Expect = 0.017
Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 13/121 (10%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQ------RMEQQEMAQQE--RKQQQELHLALK 196
R + +E +K LK+ E+ QQL Q R E+Q++++QE RK ++E +
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
Query: 197 QERR----AQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRR-RNAGKDR 251
QER + QQ + K E+ QL + ++L R ++ FL +++ R +DR
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Query: 252 R 252
+
Sbjct: 1502 K 1502
Score = 36.2 bits (82), Expect = 0.029
Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 19/129 (14%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQ-----------ELHLAL 195
+E++L ++Q L E+ + +Q L+R +Q QQ R++QQ + H
Sbjct: 385 REQQLRREQ---QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 196 KQERRAQAQQGHRPYFLKKSEQRQLALAEKFK-ELKRSKKLEN----FLSRKRRRNAGKD 250
++E+R + +Q R +LK+ E+ + E+ K +LKR ++ E + R ++
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 251 RRHLPLSKE 259
RR L +E
Sbjct: 502 RREQQLRRE 510
Score = 36.2 bits (82), Expect = 0.029
Identities = 28/96 (29%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 149 KELVKKQLKKH--LSGEEHEKLQ----QLLQRMEQQEMAQQERKQQQELHLALKQERRAQ 202
K +++QL+K L EE E+LQ + +R EQ+ ++E + QQE L++ER +
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 203 AQQGHRPYFL--KKSEQRQLALAEKFKELKRSKKLE 236
+Q + KK +Q++ L + E +R ++ E
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Score = 36.2 bits (82), Expect = 0.029
Identities = 32/109 (29%), Positives = 60/109 (55%), Gaps = 9/109 (8%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQE--RRAQAQ 204
+E+EL +Q ++ L EE EK ++ Q +E+Q ++E +Q++E L + E RR + +
Sbjct: 1112 EEEEL--QQEEEQLLREEREKRRR--QELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 205 QGHRPYFLKKSEQRQLALAEKFK---ELKRSKKLENFLSRKRRRNAGKD 250
+ +R + E+ QL E+ K E +R + E L R++R+ +D
Sbjct: 1168 RQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Score = 36.2 bits (82), Expect = 0.029
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 18/115 (15%)
Query: 148 EKELVKKQLKKHLSGEEHEKL---QQLLQRMEQQEMAQQERKQQ--QELHLALKQERRAQ 202
E++L +++ ++ L E K +QLLQ E+Q++ +QER ++ +E +QER Q
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660
Query: 203 AQQGHRPYF------LKKSEQRQLALAE---KFKE----LKRSKKLENFLSRKRR 244
+ F L++ E++QL E KF+E L+R ++ FL +++
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715
Score = 35.8 bits (81), Expect = 0.038
Identities = 32/132 (24%), Positives = 70/132 (53%), Gaps = 13/132 (9%)
Query: 136 KTYQFLNDIRAKEKELVKKQLKKHLSGEE-HEKLQQLLQRMEQQEMAQQERKQQQELHLA 194
++ Q L + +++E ++Q ++ + H ++ L+R EQ+E +++RK Q+E L
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 195 LKQ-ERRAQAQQGHRPY-----FLKKSEQRQLALAE---KFK--ELKRSKKLENFLSRKR 243
++ E + + Q+ R + L++ E++ L E KF+ EL+ ++ FL ++
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ 1381
Query: 244 R-RNAGKDRRHL 254
R R ++R+ L
Sbjct: 1382 RLRRQERERKFL 1393
Score = 34.7 bits (78), Expect = 0.085
Identities = 28/119 (23%), Positives = 63/119 (52%), Gaps = 6/119 (5%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRM--EQQEMAQQERKQ-QQELHLALKQERRAQA 203
+EK+ +++ + + EE EK + + + +++E Q+E Q Q+EL +Q R+ +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 204 QQGHRPYFLKKSEQRQLALAEKFK---ELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
Q+ R ++ +Q++L ++ + E +R ++ E ++ RR ++RR L +E
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Score = 34.7 bits (78), Expect = 0.085
Identities = 25/97 (25%), Positives = 51/97 (52%), Gaps = 5/97 (5%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQ---QQELHLALKQERRA 201
R +++ K + ++ L EE + L++ ++ +QE +Q RK+ QQE L++ER
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 202 QAQQGHRPYFLKKSE--QRQLALAEKFKELKRSKKLE 236
+ Q + ++ E Q + L + +E +R ++LE
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Score = 34.7 bits (78), Expect = 0.085
Identities = 24/90 (26%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+E+EL +Q ++ L GEE E ++ Q +E+Q ++E +Q++E L + E+R + ++
Sbjct: 1052 EEEEL--QQEEEQLLGEERETRRR--QELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLE 236
+ ++ +Q + L + +E +R ++LE
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELE 1137
Score = 34.7 bits (78), Expect = 0.085
Identities = 32/136 (23%), Positives = 72/136 (52%), Gaps = 18/136 (13%)
Query: 135 DKTYQFLNDIRAKEKELVKKQLKKHLSGE------EHEKLQQLLQRM--EQQEMAQQERK 186
++ Y+ +++ +E++L++++ +K E E E+LQQ +++ E+QE +QER+
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERE 1196
Query: 187 QQQELHLALKQERRAQAQQGHRPYF--------LKKSEQRQLALAEKFKELKRSKKLENF 238
+Q L++++R Q + K++ R + K +E ++ ++LE+
Sbjct: 1197 RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED- 1255
Query: 239 LSRKRRRNAGKDRRHL 254
S+ R R + +D +HL
Sbjct: 1256 -SQLRDRQSQQDLQHL 1270
Score = 34.7 bits (78), Expect = 0.085
Identities = 27/113 (23%), Positives = 59/113 (52%), Gaps = 15/113 (13%)
Query: 147 KEKELVKKQLKKHLSGEEH-----EKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRA 201
+E++L++++ ++ L +E E+ QQL ++ ++ +QE + Q+ L++E++
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 202 QAQQGHRPYF--------LKKSEQRQLALAEKFKELK--RSKKLENFLSRKRR 244
QQ R + ++ +QR+ KF+E + R ++ E LSR+ R
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Score = 34.7 bits (78), Expect = 0.085
Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 11/111 (9%)
Query: 145 RAKEKELVKKQL-KKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQE--RRA 201
R +E++L +++ +K L E+ + Q+L ++ ++E +QE +Q+Q +QE R+
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ----LRRQERYRKI 1749
Query: 202 QAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
++ RP + E++QL E+ ++ + ++L ++ R+ DR+
Sbjct: 1750 LEEEQLRP----EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Score = 34.3 bits (77), Expect = 0.11
Identities = 27/118 (22%), Positives = 62/118 (52%), Gaps = 10/118 (8%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +++ ++QL++ E HE Q+ EQ+ Q+ +++Q+E LK+E +
Sbjct: 413 LRREQQLRREQQLRREQEEERHE------QKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 204 -QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRR-RNAGKDRRHLPLSKE 259
+Q R LK+ ++ + E++ +L+ ++ E R+++ R ++RR L ++
Sbjct: 467 HEQERRKQQLKRDQEEE--RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Score = 34.3 bits (77), Expect = 0.11
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 23/115 (20%)
Query: 148 EKELVKKQLKKHLSGEEHEKLQQL-----LQRMEQQEMA-----QQERKQQQELHLALKQ 197
EKE + K + G E+E+ +QL R QQ++ QQER ++QE
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE------- 1282
Query: 198 ERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
RR Q + H P E+ QL E+ + +R +K + R K RR
Sbjct: 1283 RRRWQQRDRHFP------EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Score = 34.3 bits (77), Expect = 0.11
Identities = 21/84 (25%), Positives = 43/84 (51%)
Query: 150 ELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRP 209
E ++QL++ + + +QL Q E+Q++ QE ++ L+QER Q + +
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 210 YFLKKSEQRQLALAEKFKELKRSK 233
+ E+ QL L E+ + L++ +
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQER 1841
Score = 33.9 bits (76), Expect = 0.15
Identities = 25/111 (22%), Positives = 59/111 (53%), Gaps = 6/111 (5%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLL----QRMEQQEMAQQERKQQQELHLALKQERRAQ 202
+E++ +++ ++ +E + QQL +R EQQ +QE ++++E L +QE +
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE-EERREQQLRREQEEERR 373
Query: 203 AQQGHRPYFLKKSEQ-RQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
QQ R L++ +Q R+ + ++L+R ++L +R + ++++
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Score = 33.9 bits (76), Expect = 0.15
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
KE+EL +Q ++ L EE EK + R E++ ++E + QQE L++ER + +Q
Sbjct: 1082 KEEEL--QQEEEQLLREEPEKRR----RQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 207 HRPYFLKKSE--QRQLALAEKFKELKRSKKLE 236
+ ++ E Q + L + E +R ++LE
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Score = 33.9 bits (76), Expect = 0.15
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 11/128 (8%)
Query: 135 DKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQ---------ER 185
D+ ++ +R + +E + + E E+L+Q +R EQQ QQ E+
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ--EREEQQLRPQQRDGKYRWEEEQ 1827
Query: 186 KQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
Q +E L+QER Q + + +KS + + L ++ ++ +R ++ RR
Sbjct: 1828 LQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRR 1887
Query: 246 NAGKDRRH 253
+++RH
Sbjct: 1888 QQKEEQRH 1895
Score = 33.5 bits (75), Expect = 0.19
Identities = 24/125 (19%), Positives = 64/125 (51%), Gaps = 13/125 (10%)
Query: 134 FDKTYQFLNDIRAKEKELVKKQLKKHLSGE------EHEKLQQLLQRMEQQEMAQQERKQ 187
+++ Y+ ++++ +E++L++++ +K E E E+LQQ E++++ +ER+
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ-----EEEQLLGEERET 1070
Query: 188 QQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNA 247
++ L + + + QQ ++ E+R+ E+ ++ + ++L+ + R
Sbjct: 1071 RRRQELERQYRKEEELQQEEEQLLREEPEKRR--RQERERQCREEEELQQEEEQLLREER 1128
Query: 248 GKDRR 252
K RR
Sbjct: 1129 EKRRR 1133
Score = 33.5 bits (75), Expect = 0.19
Identities = 25/108 (23%), Positives = 52/108 (48%), Gaps = 4/108 (3%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+ +E +K ++ L +E E+ + L+ +Q Q++RK QE +QER Q +Q
Sbjct: 1495 RRQERDRKFREQELRSQEPER--KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHL 254
F ++ + RQ ++ +R +K L ++ R ++R+ +
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFR--LEEQKVRRQEQERKFM 1598
Score = 33.1 bits (74), Expect = 0.25
Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQ- 205
+ ++ ++Q ++ GEE + Q+ L++ ++Q ++ +Q+QE ++ERRA+ +Q
Sbjct: 136 RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQ--EREERRAEEEQL 193
Query: 206 ----GHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRN 246
GH EQ + + EL+R + E R+ R++
Sbjct: 194 QSCKGHETEEFPDEEQLR---RRELLELRRKGREEKQQQRRERQD 235
Score = 33.1 bits (74), Expect = 0.25
Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 14/109 (12%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +++E +++LK+ EE E+L+Q L+R ++E +QE +++ QE+ +
Sbjct: 647 LRREQQERREQRLKRE---EEEERLEQRLKREHEEERREQELAEEE-------QEQARER 696
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
+ P + + E A A + K R +K E R+R+ K RR
Sbjct: 697 IKSRIPKWQWQLESE--ADARQSKVYSRPRKQEG--QRRRQEQEEKRRR 741
Score = 33.1 bits (74), Expect = 0.25
Identities = 25/94 (26%), Positives = 52/94 (55%), Gaps = 6/94 (6%)
Query: 132 EVFDKTYQFLNDIRAKEK--ELVKK-QLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQ- 187
E+ + Q L + R K + EL ++ + ++ + EE + L++ ++ +QE+ +Q R++
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 188 --QQELHLALKQERRAQAQQGHRPYFLKKSEQRQ 219
QQE L++E+ + Q+ R Y ++ QRQ
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Score = 32.7 bits (73), Expect = 0.32
Identities = 26/113 (23%), Positives = 56/113 (49%), Gaps = 6/113 (5%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+E++L +++L++ EE QL Q EQ+++ +QER ++ L+ ER Q Q
Sbjct: 1712 EEQQLRRQELERKFREEE-----QLRQETEQEQLRRQERYRKILEEEQLRPEREEQ-QLR 1765
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+ K E+ QL + ++L+ + F ++ R ++++ P ++
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Score = 32.3 bits (72), Expect = 0.42
Identities = 23/108 (21%), Positives = 57/108 (52%), Gaps = 12/108 (11%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKL---QQLLQRMEQQEMAQQERKQQQELHLALKQERR 200
++ +E+EL +++ +K E+ + +QL Q EQ ++E++++QE +++++
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 201 AQAQQ----GHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRR 244
Q ++ G P ++ E+ +K++E + ++ E L R+ R
Sbjct: 966 LQQKEEQLLGEEPEKRRRQERE-----KKYREEEELQQEEEQLLREER 1008
Score = 32.3 bits (72), Expect = 0.42
Identities = 28/125 (22%), Positives = 64/125 (51%), Gaps = 20/125 (16%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMA-QQE----RKQQQELHLA---- 194
+R +E+E Q +H + + +QLLQ E+Q++ Q+ R+++Q+L
Sbjct: 1652 LRRQERE----QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 195 --LKQERRAQAQQGHRPY-----FLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNA 247
L++E++ + Q+ R + +++EQ QL E+++++ ++L ++ R
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Query: 248 GKDRR 252
+DR+
Sbjct: 1768 ERDRK 1772
Score = 32.3 bits (72), Expect = 0.42
Identities = 18/74 (24%), Positives = 42/74 (56%), Gaps = 3/74 (4%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQE---RRAQA 203
++++ ++++ + EE Q+ +R EQ+ ++E+K++QE L++E R+ +
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 204 QQGHRPYFLKKSEQ 217
+Q HR KS++
Sbjct: 1892 EQRHRQVGEIKSQE 1905
Score = 31.6 bits (70), Expect = 0.72
Identities = 29/103 (28%), Positives = 53/103 (51%), Gaps = 18/103 (17%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +++E +++LK+ E E+ QQLL+ EQ+E ++QQ+L +QERR Q
Sbjct: 609 RLEQEERREQRLKRE--EPEEERRQQLLKSEEQEE------RRQQQLRRE-QQERREQR- 658
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNA 247
LK+ E+ + L ++ K ++ E L+ + + A
Sbjct: 659 -------LKREEEEE-RLEQRLKREHEEERREQELAEEEQEQA 693
Score = 31.6 bits (70), Expect = 0.72
Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 8/110 (7%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+E++L +++ ++ LS +E ++ +L ++ +++ +QERK ++ +QE + Q +Q
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ--EQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRK---RRRNAGKDRRH 253
F E QL + ++L R ++ FL + RR+ + RH
Sbjct: 1617 RDRKF---REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Score = 30.8 bits (68), Expect = 1.2
Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 174 RMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSK 233
R + +E Q+R+Q+++ ++R+ + + G R ++ ++R+LA E ++S+
Sbjct: 102 RCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE-----EQSE 156
Query: 234 KLENFLSRKRRR 245
K E R R+R
Sbjct: 157 KQERLEQRDRQR 168
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/112 (18%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Query: 147 KEKELVKKQLK-KHLSGEEHEKLQQLLQRMEQQE---MAQQERKQQQELHLALKQERRAQ 202
+E++L ++Q + +H E E+ +Q L+R +++ + ++E ++ E +Q +R Q
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 203 AQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHL 254
++ + + E+R+ + ++L+R ++ KR+ + ++ L
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Score = 30.0 bits (66), Expect = 2.1
Identities = 26/123 (21%), Positives = 60/123 (48%), Gaps = 23/123 (18%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQ---------------QERKQQQEL 191
+EKE ++Q ++ + + ++ LQR E+ + Q QE+++ Q+
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Query: 192 HLALKQERRAQAQQGH-RPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD 250
L++ER+ + + +P ++ + Q L E+ +EL+R + R++RR ++
Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE-------REKRRRQEQE 927
Query: 251 RRH 253
R++
Sbjct: 928 RQY 930
Score = 30.0 bits (66), Expect = 2.1
Identities = 28/136 (20%), Positives = 60/136 (44%), Gaps = 20/136 (14%)
Query: 135 DKTYQFLNDIRAKEKELVKKQLKKHLSG--EEHEKLQQLLQRMEQQEMAQQERKQQQELH 192
+K QFL + ++ +QL++ G E+ E+ + QR +Q+ Q E ++++ H
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 193 LA---------------LKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLEN 237
L QE + Q+ R ++ ++RQ E+ ++ + E
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE- 946
Query: 238 FLSRKRRRNAGKDRRH 253
R++RR ++R++
Sbjct: 947 --EREKRRRQERERQY 960
Score = 30.0 bits (66), Expect = 2.1
Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 8/88 (9%)
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
E++ V++Q ++ E+ +Q L+R E Q+ +QER ++ L QER + QQ H
Sbjct: 1584 EEQKVRRQEQERKFMED----EQQLRRQEGQQQLRQERDRKFREDEQLLQER--EEQQLH 1637
Query: 208 RPYFLKK--SEQRQLALAEKFKELKRSK 233
R +K E+ QL E+ ++L+ +
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Score = 29.3 bits (64), Expect = 3.6
Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 11/116 (9%)
Query: 153 KKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQE---------LHLALKQERRAQA 203
+KQ + E+ EK ++ ++ QE + R+QQ+E K ER Q
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
P L++ +RQL E+ + +R E ++RR+ +++ L +E
Sbjct: 784 LSARPP--LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Score = 29.3 bits (64), Expect = 3.6
Identities = 23/113 (20%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
Query: 149 KELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQ---AQQ 205
+E ++QL++ + + +QL E+Q++ +QER ++ L+QER Q +Q+
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
Query: 206 GHRPY-----FLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRH 253
R + ++ E++QL ++ + + ++ +++R +DR++
Sbjct: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY 1845
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 48.1 bits (113), Expect = 7e-06
Identities = 30/98 (30%), Positives = 60/98 (61%), Gaps = 5/98 (5%)
Query: 154 KQLKKHLSGEEHEKLQQLLQRMEQ-QEMAQQERKQQQELHLALKQERRAQAQQGHRPYFL 212
++LK+ L GE E +Q++++ ++ +E+ Q ++++EL AL RA+ + G R L
Sbjct: 1079 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA---RAEDEGGARAQLL 1135
Query: 213 KKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD 250
K + Q ALAE ++L+ S+++ + K+RR+ G++
Sbjct: 1136 KSLREAQAALAEAQEDLE-SERVARTKAEKQRRDLGEE 1172
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 48.1 bits (113), Expect = 7e-06
Identities = 30/98 (30%), Positives = 60/98 (61%), Gaps = 5/98 (5%)
Query: 154 KQLKKHLSGEEHEKLQQLLQRMEQ-QEMAQQERKQQQELHLALKQERRAQAQQGHRPYFL 212
++LK+ L GE E +Q++++ ++ +E+ Q ++++EL AL RA+ + G R L
Sbjct: 1071 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA---RAEDEGGARAQLL 1127
Query: 213 KKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD 250
K + Q ALAE ++L+ S+++ + K+RR+ G++
Sbjct: 1128 KSLREAQAALAEAQEDLE-SERVARTKAEKQRRDLGEE 1164
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 48.1 bits (113), Expect = 7e-06
Identities = 30/98 (30%), Positives = 60/98 (61%), Gaps = 5/98 (5%)
Query: 154 KQLKKHLSGEEHEKLQQLLQRMEQ-QEMAQQERKQQQELHLALKQERRAQAQQGHRPYFL 212
++LK+ L GE E +Q++++ ++ +E+ Q ++++EL AL RA+ + G R L
Sbjct: 1112 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA---RAEDEGGARAQLL 1168
Query: 213 KKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD 250
K + Q ALAE ++L+ S+++ + K+RR+ G++
Sbjct: 1169 KSLREAQAALAEAQEDLE-SERVARTKAEKQRRDLGEE 1205
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 47.8 bits (112), Expect = 1e-05
Identities = 46/224 (20%), Positives = 102/224 (45%), Gaps = 24/224 (10%)
Query: 45 TSNMSFEELLELQSQVGTKTYKQLVAGN------SPKKQASRPPIQNA------CVA--- 89
+S +S ELL LQ Q + +QL+ SPK + P+Q C+
Sbjct: 41 SSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHS 100
Query: 90 --DKHRPLEMSAKIRVPFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAK 147
D H + + V + V +++ + + LS + + + + +
Sbjct: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL 160
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
++ K+Q + HL + ++ QQ Q+ +QQ+ QQ+++QQQ+ +Q+++ Q G
Sbjct: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK 220
Query: 208 RPYFLKKSEQRQLALA-------EKFKELKRSKKLENFLSRKRR 244
+ ++ +Q+Q LA ++ ++++ ++ ++ LS +R+
Sbjct: 221 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
>gi|166706903 guanylate binding protein 1, interferon-inducible,
67kDa [Homo sapiens]
Length = 592
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/156 (26%), Positives = 78/156 (50%), Gaps = 16/156 (10%)
Query: 105 FLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLND--------IRAKEKELVKKQL 156
F++++ + KK +PR + E + + K+ + + D + KEKE+ +++
Sbjct: 436 FVQKLQDLKKKYYEEPR-KGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERV 494
Query: 157 KKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQ---ELHLALKQERRAQAQQGHRPYFLK 213
K S + K+ Q +QR +Q M Q+ER Q+ +L ++ +R ++ R LK
Sbjct: 495 KAE-SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALK 553
Query: 214 KSEQRQLALAEKFKELKRSKK--LENFLSRKRRRNA 247
EQ QL L E F++ R K +++ ++ RRR A
Sbjct: 554 LQEQEQL-LKEGFQKESRIMKNEIQDLQTKMRRRKA 588
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 46.2 bits (108), Expect = 3e-05
Identities = 23/83 (27%), Positives = 50/83 (60%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
++++L ++Q + ++ ++ QQL Q+ QQ+ QQ+ +QQQ+ L +Q++ Q QQ
Sbjct: 3902 QQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQ 3961
Query: 207 HRPYFLKKSEQRQLALAEKFKEL 229
+ F ++ +Q+Q+ L + + L
Sbjct: 3962 QQQQFQQQQQQQQMGLLNQSRTL 3984
Score = 41.2 bits (95), Expect = 0.001
Identities = 20/78 (25%), Positives = 47/78 (60%)
Query: 158 KHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQ 217
+ L ++ + QQ LQ+ +QQ++ QQ++ QQQ+L +Q++ Q QQ ++ +Q
Sbjct: 3898 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQ 3957
Query: 218 RQLALAEKFKELKRSKKL 235
+Q ++F++ ++ +++
Sbjct: 3958 QQQQQQQQFQQQQQQQQM 3975
Score = 39.3 bits (90), Expect = 0.003
Identities = 22/94 (23%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
++++L ++QL++ ++ ++ QQ + +QQ++ QQ+++QQQ+ +Q++ Q
Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLS 240
++ +Q+Q+AL +K L++F S
Sbjct: 3982 RTLLSPQQQQQQQVALGPGMP----AKPLQHFSS 4011
Score = 38.5 bits (88), Expect = 0.006
Identities = 24/101 (23%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
++ L+ + LS + LQQL Q+ +Q + QQ ++QQQ+ +Q ++ Q QQ
Sbjct: 3877 QQSLMSHSGQPKLSAQPMGSLQQL-QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Query: 208 RPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAG 248
+ L++ +Q+QL ++ + ++ ++ + F +++++ G
Sbjct: 3936 QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976
Score = 30.8 bits (68), Expect = 1.2
Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 164 EHEKLQQLLQRME-QQEMAQQERKQQQELHLALKQERRAQAQQG 206
+ +LQ QRM+ Q++ QQ+++QQQ+ HL + + Q QQG
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQG 3760
Score = 29.6 bits (65), Expect = 2.7
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 9/93 (9%)
Query: 135 DKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLA 194
D+ + + + A E L+ + L +H +E +K QQL Q + AQQ+++QQQ+ H
Sbjct: 3231 DELDKMESSLVASELPLLIEDLLEH-EKKELQKKQQL---SAQLQPAQQQQQQQQQ-HSL 3285
Query: 195 LKQERRAQA----QQGHRPYFLKKSEQRQLALA 223
L AQA +G P +Q L LA
Sbjct: 3286 LSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLA 3318
Score = 28.1 bits (61), Expect = 8.0
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 145 RAKEKELVKKQLKKHLSGEEH-----EKLQQLLQRMEQ-QEMAQQERKQQQELHLALKQE 198
R K L KQ +G E EKL+ + ++ + Q+ Q RKQQ+E + +
Sbjct: 3536 RKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEY 3595
Query: 199 RRAQAQQGHRPYFLKKSEQRQLALA 223
R Q QQ + ++ LAL+
Sbjct: 3596 RNKQQQQQQQQQQQQQQHSAVLALS 3620
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 46.2 bits (108), Expect = 3e-05
Identities = 21/93 (22%), Positives = 52/93 (55%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
++ ++ L ++Q ++ ++ LQQ Q+ +QQ+ Q+ QQ+ ++Q+++ Q
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ 212
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLE 236
QQ + + +K Q Q + ++ ++L+R +L+
Sbjct: 213 QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQ 245
Score = 36.2 bits (82), Expect = 0.029
Identities = 21/81 (25%), Positives = 42/81 (51%)
Query: 139 QFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQE 198
QF ++ +++ ++Q ++HL H+ QQ+ Q+ +Q + Q + QQQ+ +Q+
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 199 RRAQAQQGHRPYFLKKSEQRQ 219
++ QA Q P +Q Q
Sbjct: 259 QQQQALQAQPPIQQPPMQQPQ 279
Score = 35.0 bits (79), Expect = 0.065
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 139 QFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQ---ELHLAL 195
QF +A ++ ++Q ++ ++ QQ ++QQ+ QQ+++QQQ +LH
Sbjct: 168 QFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQN 227
Query: 196 KQERRAQAQQGHRPYFLKKSEQRQ 219
+Q+ + Q QQ R L+ +Q+Q
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQ 251
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 46.2 bits (108), Expect = 3e-05
Identities = 21/93 (22%), Positives = 52/93 (55%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
++ ++ L ++Q ++ ++ LQQ Q+ +QQ+ Q+ QQ+ ++Q+++ Q
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ 212
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLE 236
QQ + + +K Q Q + ++ ++L+R +L+
Sbjct: 213 QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQ 245
Score = 36.2 bits (82), Expect = 0.029
Identities = 21/81 (25%), Positives = 42/81 (51%)
Query: 139 QFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQE 198
QF ++ +++ ++Q ++HL H+ QQ+ Q+ +Q + Q + QQQ+ +Q+
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 199 RRAQAQQGHRPYFLKKSEQRQ 219
++ QA Q P +Q Q
Sbjct: 259 QQQQALQAQPPIQQPPMQQPQ 279
Score = 35.0 bits (79), Expect = 0.065
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 139 QFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQ---ELHLAL 195
QF +A ++ ++Q ++ ++ QQ ++QQ+ QQ+++QQQ +LH
Sbjct: 168 QFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQN 227
Query: 196 KQERRAQAQQGHRPYFLKKSEQRQ 219
+Q+ + Q QQ R L+ +Q+Q
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQ 251
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 44.7 bits (104), Expect = 8e-05
Identities = 25/119 (21%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Query: 141 LNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERR 200
LND++AK++ LVK++ K+ E+ ++LQ L+++ ++E ++ +++ L L++E
Sbjct: 70 LNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEE 129
Query: 201 AQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
++ + ++ E+ + + K ++L ++ ++ R R ++R L +E
Sbjct: 130 GGEEEEEAAMYEEEMEREE--ITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQE 186
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 44.7 bits (104), Expect = 8e-05
Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 7/114 (6%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R K K+ KK+ +K E +K ++ +R E++ ++ERK+++ ++ER+ + +
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKER-ERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 205 QGHRPYFLKK------SEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
+G R KK ++R+ E+ KE +R ++ E RK+ R K+R+
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Score = 40.4 bits (93), Expect = 0.002
Identities = 27/102 (26%), Positives = 53/102 (51%), Gaps = 8/102 (7%)
Query: 153 KKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFL 212
KK+ KK G+E E+ ++ ++ ++ ++ RK+++E +++R + Q+G R
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE------KKKRERKQRGRRERKK 116
Query: 213 KKSEQRQLALAEKFKELKRSK--KLENFLSRKRRRNAGKDRR 252
KK + + ++ +E KR K K + RKR + GK R
Sbjct: 117 KKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
Score = 38.9 bits (89), Expect = 0.005
Identities = 27/113 (23%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 145 RAKEKELVKKQLKKHLSG---EEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQ--ER 199
R KE+E +K+ +K +E K ++ ++ E+++ ++ERK+++E ++ +R
Sbjct: 71 RGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130
Query: 200 RAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
R + ++ R +K +R+ ++ ++ K+ KK E R+R R K R
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183
Score = 36.2 bits (82), Expect = 0.029
Identities = 25/99 (25%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
KE+E KQ ++ ++ K ++ +R ++E ++ERK+++ K+E R + ++
Sbjct: 121 KERERENKQ-RRERKRKKRRKKKRRKERKREKERGKRERKRKKR-----KKEEREKKRER 174
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
+R K+ E+++ +K ++ +R KK E RK R
Sbjct: 175 NRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Score = 35.8 bits (81), Expect = 0.038
Identities = 28/114 (24%), Positives = 62/114 (54%), Gaps = 9/114 (7%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+E+E K++ +K E +K ++ ++ E+ + +++RK++++ +++ R + ++
Sbjct: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK-----QRKERREKERR 95
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKK-LENFLSRKRRRNAGKDRRHLPLSKE 259
R KK E++Q E+ K+ +R ++ EN R+R+R K RR KE
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR---KKRRKKKRRKE 146
Score = 33.1 bits (74), Expect = 0.25
Identities = 22/104 (21%), Positives = 52/104 (50%), Gaps = 9/104 (8%)
Query: 149 KELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHR 208
K +++ ++ E EK ++ ++ ++E ++E+K++++ ++ER+ + ++ R
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 209 PYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
E+R+ E+ K K KK E +R R K+R+
Sbjct: 87 ------KERRE---KERRKRKKEKKKRERKQRGRRERKKKKERK 121
Score = 30.8 bits (68), Expect = 1.2
Identities = 24/103 (23%), Positives = 56/103 (54%), Gaps = 14/103 (13%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R K++ +K+ K+ E K ++ +R +++E ++ERK+++E ++ERR + +
Sbjct: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE-----RKERRERKK 193
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNA 247
+ +K E+R+ E+ K+ K ++ ++ + R R +A
Sbjct: 194 E-------RKKERRK--KKERKKDRKTDRQTDSQVFRPLRESA 227
Score = 29.6 bits (65), Expect = 2.7
Identities = 18/101 (17%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 159 HLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQR 218
H+S ++ + + ++E ++ER+++++ K++++ + ++ + K+ E+
Sbjct: 24 HISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83
Query: 219 QLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+ + KE ++ KK +K+R + RR KE
Sbjct: 84 KQRKERREKERRKRKK-----EKKKRERKQRGRRERKKKKE 119
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 43.1 bits (100), Expect = 2e-04
Identities = 27/89 (30%), Positives = 56/89 (62%), Gaps = 2/89 (2%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQER-RAQAQQ 205
K++E+ +K+ K+ + E+ E +++L Q EQ + AQQE ++Q L L+QER RAQ++
Sbjct: 328 KKREMAEKE-KEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEA 386
Query: 206 GHRPYFLKKSEQRQLALAEKFKELKRSKK 234
+++E+ + AL + ++ K++++
Sbjct: 387 EKLAKERQEAEEAKEALLQASRDQKKTQE 415
Score = 30.4 bits (67), Expect = 1.6
Identities = 30/115 (26%), Positives = 59/115 (51%), Gaps = 15/115 (13%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQ---LLQRMEQQEMAQQER----KQQQELHLALKQ 197
R K + +Q+K E+H+K + L +++EMA++E+ ++++EL LKQ
Sbjct: 294 RRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQ 353
Query: 198 ----ERRAQ---AQQGHRPYFLKKSEQRQLALAEKF-KELKRSKKLENFLSRKRR 244
++AQ +Q R L++ +R + AEK KE + +++ + L + R
Sbjct: 354 IEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASR 408
Score = 28.9 bits (63), Expect = 4.7
Identities = 18/75 (24%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 172 LQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKEL-K 230
+Q+M+ Q ++ +KQ + L ++++R A++ +K E+ + L E+ K++ +
Sbjct: 302 VQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEK-----EKIEREKEELMERLKQIEE 356
Query: 231 RSKKLENFLSRKRRR 245
++KK + L + RR
Sbjct: 357 QTKKAQQELEEQTRR 371
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 42.4 bits (98), Expect = 4e-04
Identities = 26/104 (25%), Positives = 60/104 (57%), Gaps = 8/104 (7%)
Query: 149 KELVKKQLKK-HLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
+E KKQ ++ HL + ++ QQ Q+ +QQ+ QQ+++QQQ+ +Q+++ Q G
Sbjct: 44 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK 103
Query: 208 RPYFLKKSEQRQLALA-------EKFKELKRSKKLENFLSRKRR 244
+ ++ +Q+Q LA ++ ++++ ++ ++ LS +R+
Sbjct: 104 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 147
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/93 (24%), Positives = 54/93 (58%), Gaps = 8/93 (8%)
Query: 151 LVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPY 210
L ++QL++ ++ + QLLQ+ +QQ+ QQ+++QQQ+ +Q+++ Q QQ
Sbjct: 38 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 92
Query: 211 FLKKSEQRQLALAEKFKELKRSKKLENFLSRKR 243
+ +Q+Q ++ KE ++ ++ + L+ ++
Sbjct: 93 ---QQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 122
Score = 39.3 bits (90), Expect = 0.003
Identities = 20/59 (33%), Positives = 39/59 (66%), Gaps = 5/59 (8%)
Query: 166 EKLQQLLQR-----MEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQ 219
++LQ LLQ+ ++QQ++ + +KQQ++LHL L Q+++ Q QQ + ++ +Q+Q
Sbjct: 24 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82
Score = 29.6 bits (65), Expect = 2.7
Identities = 15/66 (22%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 170 QLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH-RPYFLKKSEQRQLALAEKFKE 228
Q++ + Q++ QQ+ Q+L L+Q++ QQ + ++ K+ EQ L L ++ ++
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 64
Query: 229 LKRSKK 234
++ ++
Sbjct: 65 QQQQQQ 70
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/172 (20%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Query: 104 PFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGE 163
P L Q+ + K A + E + ++ + ++R +++E++++Q ++
Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
Query: 164 EHEKL-----QQLLQRMEQQEMA----QQER--KQQQELHLALKQERRAQAQQGHRPYFL 212
E E+L ++ L+R +QE+A ++E +QQ+E L++ RR + ++ + L
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
Query: 213 KKSEQRQLALAEKFKELKR-----SKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+K E+ A + +E +R ++E +R R + R+ L + ++
Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
Score = 36.6 bits (83), Expect = 0.022
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +E L ++ L EE E+ ++ L+ Q+E+ +Q ++QQ+ L +Q+++ Q
Sbjct: 854 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLA 913
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRS--KKLENFLSRKRRRNAGKDRRHL 254
Q P +Q + L + +KLE R+ R + +R L
Sbjct: 914 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 965
Score = 32.0 bits (71), Expect = 0.55
Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 8/102 (7%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +E+E +K+L E + + + QR +QQE ++ ++QQQ+ LA + + + +
Sbjct: 869 LRHEEEERKRKEL------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLA-QMKLPSSS 921
Query: 204 QQGHRPYFLKKSEQRQLALAEKFK-ELKRSKKLENFLSRKRR 244
G + Q L+LAE K E +R ++L R++R
Sbjct: 922 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 963
Score = 31.2 bits (69), Expect = 0.94
Identities = 12/36 (33%), Positives = 27/36 (75%)
Query: 170 QLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQ 205
Q L+ ++++ +++R+QQ+EL AL+Q+++ Q Q+
Sbjct: 944 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
Score = 30.4 bits (67), Expect = 1.6
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQ 197
+++EL +HL ++ QQ Q + QQ+ A +QQQ+L L L+Q
Sbjct: 606 RQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 656
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/172 (20%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Query: 104 PFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGE 163
P L Q+ + K A + E + ++ + ++R +++E++++Q ++
Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
Query: 164 EHEKL-----QQLLQRMEQQEMA----QQER--KQQQELHLALKQERRAQAQQGHRPYFL 212
E E+L ++ L+R +QE+A ++E +QQ+E L++ RR + ++ + L
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
Query: 213 KKSEQRQLALAEKFKELKR-----SKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+K E+ A + +E +R ++E +R R + R+ L + ++
Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
Score = 36.6 bits (83), Expect = 0.022
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +E L ++ L EE E+ ++ L+ Q+E+ +Q ++QQ+ L +Q+++ Q
Sbjct: 881 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLA 940
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRS--KKLENFLSRKRRRNAGKDRRHL 254
Q P +Q + L + +KLE R+ R + +R L
Sbjct: 941 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 992
Score = 32.0 bits (71), Expect = 0.55
Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 8/102 (7%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +E+E +K+L E + + + QR +QQE ++ ++QQQ+ LA + + + +
Sbjct: 896 LRHEEEERKRKEL------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLA-QMKLPSSS 948
Query: 204 QQGHRPYFLKKSEQRQLALAEKFK-ELKRSKKLENFLSRKRR 244
G + Q L+LAE K E +R ++L R++R
Sbjct: 949 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 990
Score = 31.2 bits (69), Expect = 0.94
Identities = 12/36 (33%), Positives = 27/36 (75%)
Query: 170 QLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQ 205
Q L+ ++++ +++R+QQ+EL AL+Q+++ Q Q+
Sbjct: 971 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
Score = 30.4 bits (67), Expect = 1.6
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQ 197
+++EL +HL ++ QQ Q + QQ+ A +QQQ+L L L+Q
Sbjct: 633 RQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 683
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/172 (20%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Query: 104 PFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGE 163
P L Q+ + K A + E + ++ + ++R +++E++++Q ++
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 164 EHEKL-----QQLLQRMEQQEMA----QQER--KQQQELHLALKQERRAQAQQGHRPYFL 212
E E+L ++ L+R +QE+A ++E +QQ+E L++ RR + ++ + L
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 213 KKSEQRQLALAEKFKELKR-----SKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+K E+ A + +E +R ++E +R R + R+ L + ++
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
Score = 36.6 bits (83), Expect = 0.022
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +E L ++ L EE E+ ++ L+ Q+E+ +Q ++QQ+ L +Q+++ Q
Sbjct: 860 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLA 919
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRS--KKLENFLSRKRRRNAGKDRRHL 254
Q P +Q + L + +KLE R+ R + +R L
Sbjct: 920 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Score = 32.0 bits (71), Expect = 0.55
Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 8/102 (7%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +E+E +K+L E + + + QR +QQE ++ ++QQQ+ LA + + + +
Sbjct: 875 LRHEEEERKRKEL------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLA-QMKLPSSS 927
Query: 204 QQGHRPYFLKKSEQRQLALAEKFK-ELKRSKKLENFLSRKRR 244
G + Q L+LAE K E +R ++L R++R
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 969
Score = 31.2 bits (69), Expect = 0.94
Identities = 12/36 (33%), Positives = 27/36 (75%)
Query: 170 QLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQ 205
Q L+ ++++ +++R+QQ+EL AL+Q+++ Q Q+
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
Score = 30.4 bits (67), Expect = 1.6
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQ 197
+++EL +HL ++ QQ Q + QQ+ A +QQQ+L L L+Q
Sbjct: 612 RQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/172 (20%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Query: 104 PFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGE 163
P L Q+ + K A + E + ++ + ++R +++E++++Q ++
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 164 EHEKL-----QQLLQRMEQQEMA----QQER--KQQQELHLALKQERRAQAQQGHRPYFL 212
E E+L ++ L+R +QE+A ++E +QQ+E L++ RR + ++ + L
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 213 KKSEQRQLALAEKFKELKR-----SKKLENFLSRKRRRNAGKDRRHLPLSKE 259
+K E+ A + +E +R ++E +R R + R+ L + ++
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
Score = 36.6 bits (83), Expect = 0.022
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +E L ++ L EE E+ ++ L+ Q+E+ +Q ++QQ+ L +Q+++ Q
Sbjct: 860 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLA 919
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRS--KKLENFLSRKRRRNAGKDRRHL 254
Q P +Q + L + +KLE R+ R + +R L
Sbjct: 920 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Score = 32.0 bits (71), Expect = 0.55
Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 8/102 (7%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +E+E +K+L E + + + QR +QQE ++ ++QQQ+ LA + + + +
Sbjct: 875 LRHEEEERKRKEL------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLA-QMKLPSSS 927
Query: 204 QQGHRPYFLKKSEQRQLALAEKFK-ELKRSKKLENFLSRKRR 244
G + Q L+LAE K E +R ++L R++R
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 969
Score = 31.2 bits (69), Expect = 0.94
Identities = 12/36 (33%), Positives = 27/36 (75%)
Query: 170 QLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQ 205
Q L+ ++++ +++R+QQ+EL AL+Q+++ Q Q+
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
Score = 30.4 bits (67), Expect = 1.6
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQ 197
+++EL +HL ++ QQ Q + QQ+ A +QQQ+L L L+Q
Sbjct: 612 RQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 42.4 bits (98), Expect = 4e-04
Identities = 27/129 (20%), Positives = 60/129 (46%)
Query: 124 DLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQ 183
D + + K + I+A +EL +K K+ + E+L++ Q E++E ++
Sbjct: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
Query: 184 ERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR 243
++++E ++E R + + R + + + + + RS+ + SR+R
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322
Query: 244 RRNAGKDRR 252
RR+ +DRR
Sbjct: 323 RRSRSRDRR 331
Score = 35.8 bits (81), Expect = 0.038
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
+ +E+E +++ K+ EE EK +R +E +++R + + H + +RR
Sbjct: 259 KEREREREERERKRRREEEEREK-----ERARDRE--RRKRSRSRSRHSSRTSDRRCSRS 311
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
+ H+ ++ + + + + RS++ SR RRR+ +DR+
Sbjct: 312 RDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRK 359
Score = 35.0 bits (79), Expect = 0.065
Identities = 24/115 (20%), Positives = 52/115 (45%), Gaps = 19/115 (16%)
Query: 153 KKQLKKHLSGEEH--------------EKLQQLLQRMEQQEMAQQERKQQQELHLALKQE 198
+ ++ HL G++H EKL++ + ++ E ++E+++++E ++E
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
Query: 199 RRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRH 253
R + ++ R + E+R+ A + KRS+ SR R + R H
Sbjct: 265 REERERKRRR-----EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDH 314
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 42.4 bits (98), Expect = 4e-04
Identities = 27/129 (20%), Positives = 60/129 (46%)
Query: 124 DLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQ 183
D + + K + I+A +EL +K K+ + E+L++ Q E++E ++
Sbjct: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
Query: 184 ERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR 243
++++E ++E R + + R + + + + + RS+ + SR+R
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322
Query: 244 RRNAGKDRR 252
RR+ +DRR
Sbjct: 323 RRSRSRDRR 331
Score = 35.8 bits (81), Expect = 0.038
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
+ +E+E +++ K+ EE EK +R +E +++R + + H + +RR
Sbjct: 259 KEREREREERERKRRREEEEREK-----ERARDRE--RRKRSRSRSRHSSRTSDRRCSRS 311
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
+ H+ ++ + + + + RS++ SR RRR+ +DR+
Sbjct: 312 RDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRK 359
Score = 35.0 bits (79), Expect = 0.065
Identities = 24/115 (20%), Positives = 52/115 (45%), Gaps = 19/115 (16%)
Query: 153 KKQLKKHLSGEEH--------------EKLQQLLQRMEQQEMAQQERKQQQELHLALKQE 198
+ ++ HL G++H EKL++ + ++ E ++E+++++E ++E
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
Query: 199 RRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRH 253
R + ++ R + E+R+ A + KRS+ SR R + R H
Sbjct: 265 REERERKRRR-----EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDH 314
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 42.0 bits (97), Expect = 5e-04
Identities = 34/132 (25%), Positives = 68/132 (51%), Gaps = 14/132 (10%)
Query: 135 DKTYQFLNDIRAKEK---------ELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQER 185
+K Q L ++R KE+ E K++ + + + E+L+++LQ E+ E ++E+
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 186 KQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR-R 244
K+Q E A E+ +A++ L + + ++ A A+K +E++ +K E R R
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEER----LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 651
Query: 245 RNAGKDRRHLPL 256
+ ++RRH L
Sbjct: 652 QQEEEERRHQEL 663
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/147 (21%), Positives = 70/147 (47%), Gaps = 11/147 (7%)
Query: 113 SKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLL 172
+KK A + +++ E + ++L +E+E ++L + EE E+L++
Sbjct: 623 AKKKAAAKKMEEVEARRKQEEEARRLRWLQQ---EEEERRHQELLQKKKEEEQERLRKAA 679
Query: 173 QRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRS 232
+ E +QER++Q+ +QERR Q ++ ++ ++RQLA E+ +E +R
Sbjct: 680 EAKRLAEQREQERREQER----REQERREQERREQE----RREQERQLAEQERRREQERL 731
Query: 233 KKLENFLSRKRRRNAGKDRRHLPLSKE 259
+ R++ K++ L ++
Sbjct: 732 QAERELQEREKALRLQKEQLQRELEEK 758
Score = 39.7 bits (91), Expect = 0.003
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 3/103 (2%)
Query: 143 DIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQ 202
++ K+KE +++L+K + E +Q Q +QE +QER++Q+ +++ R
Sbjct: 662 ELLQKKKEEEQERLRK--AAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719
Query: 203 AQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
A+Q R + +R+L EK L++ ++L+ L K+++
Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQK-EQLQRELEEKKKK 761
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/165 (20%), Positives = 75/165 (45%), Gaps = 3/165 (1%)
Query: 90 DKHRPLEMSAKIRVPFLRQVVPISKKVA--RDPRFDDLSGEYNPEVFDKTYQFLNDIRAK 147
DK R LE R LR+V+ ++V ++ + + ++ ++ +KT + + A+
Sbjct: 562 DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF-AQIDEKTEKAKEERLAE 620
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
EK K KK E K ++ +R+ + ++ER+ Q+ L ++E+ +
Sbjct: 621 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 680
Query: 208 RPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
++ EQ + + +E + ++ E + R+ A ++RR
Sbjct: 681 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725
Score = 38.1 bits (87), Expect = 0.008
Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 12/117 (10%)
Query: 146 AKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQ------EMAQQERKQQQELHLALK--Q 197
A+ K L +++ ++ E E+ ++ +R EQ+ ++A+QER+++QE A + Q
Sbjct: 679 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQ 738
Query: 198 ER----RAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD 250
ER R Q +Q R KK ++ Q LAE+ + ++ KK + + N D
Sbjct: 739 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVD 795
Score = 33.5 bits (75), Expect = 0.19
Identities = 23/104 (22%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
+A E + + +Q ++ +E + ++ Q +QE +QER+ ++ ++ +A+ +
Sbjct: 677 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 736
Query: 205 QGHRPYFLK-KSEQRQLALAEKFKELKRSKKLENFLSRKRRRNA 247
R L+ + EQ Q L EK K+ ++ + E L ++ + A
Sbjct: 737 LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 42.0 bits (97), Expect = 5e-04
Identities = 34/132 (25%), Positives = 68/132 (51%), Gaps = 14/132 (10%)
Query: 135 DKTYQFLNDIRAKEK---------ELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQER 185
+K Q L ++R KE+ E K++ + + + E+L+++LQ E+ E ++E+
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591
Query: 186 KQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR-R 244
K+Q E A E+ +A++ L + + ++ A A+K +E++ +K E R R
Sbjct: 592 KKQIEQKFAQIDEKTEKAKEER----LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
Query: 245 RNAGKDRRHLPL 256
+ ++RRH L
Sbjct: 648 QQEEEERRHQEL 659
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/147 (21%), Positives = 70/147 (47%), Gaps = 11/147 (7%)
Query: 113 SKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLL 172
+KK A + +++ E + ++L +E+E ++L + EE E+L++
Sbjct: 619 AKKKAAAKKMEEVEARRKQEEEARRLRWLQQ---EEEERRHQELLQKKKEEEQERLRKAA 675
Query: 173 QRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRS 232
+ E +QER++Q+ +QERR Q ++ ++ ++RQLA E+ +E +R
Sbjct: 676 EAKRLAEQREQERREQER----REQERREQERREQE----RREQERQLAEQERRREQERL 727
Query: 233 KKLENFLSRKRRRNAGKDRRHLPLSKE 259
+ R++ K++ L ++
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEK 754
Score = 39.7 bits (91), Expect = 0.003
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 3/103 (2%)
Query: 143 DIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQ 202
++ K+KE +++L+K + E +Q Q +QE +QER++Q+ +++ R
Sbjct: 658 ELLQKKKEEEQERLRK--AAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
Query: 203 AQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
A+Q R + +R+L EK L++ ++L+ L K+++
Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQK-EQLQRELEEKKKK 757
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/165 (20%), Positives = 75/165 (45%), Gaps = 3/165 (1%)
Query: 90 DKHRPLEMSAKIRVPFLRQVVPISKKVA--RDPRFDDLSGEYNPEVFDKTYQFLNDIRAK 147
DK R LE R LR+V+ ++V ++ + + ++ ++ +KT + + A+
Sbjct: 558 DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF-AQIDEKTEKAKEERLAE 616
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
EK K KK E K ++ +R+ + ++ER+ Q+ L ++E+ +
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676
Query: 208 RPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
++ EQ + + +E + ++ E + R+ A ++RR
Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
Score = 38.1 bits (87), Expect = 0.008
Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 12/117 (10%)
Query: 146 AKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQ------EMAQQERKQQQELHLALK--Q 197
A+ K L +++ ++ E E+ ++ +R EQ+ ++A+QER+++QE A + Q
Sbjct: 675 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQ 734
Query: 198 ER----RAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKD 250
ER R Q +Q R KK ++ Q LAE+ + ++ KK + + N D
Sbjct: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVD 791
Score = 33.5 bits (75), Expect = 0.19
Identities = 23/104 (22%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
+A E + + +Q ++ +E + ++ Q +QE +QER+ ++ ++ +A+ +
Sbjct: 673 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 732
Query: 205 QGHRPYFLK-KSEQRQLALAEKFKELKRSKKLENFLSRKRRRNA 247
R L+ + EQ Q L EK K+ ++ + E L ++ + A
Sbjct: 733 LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/110 (22%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 155 QLKKHLSGEEHEKLQQLLQRMEQQEMAQ--QERKQQQELHLALKQERRAQAQQGHRPYFL 212
Q+ + ++H+ Q Q+ +QQ+M Q Q++ QQ ++H ++Q+ + Q Q H L
Sbjct: 426 QVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHL 485
Query: 213 KKSE---QRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
++ + Q+Q+ + ++L++ +L+ L + ++ R+H P++ +
Sbjct: 486 QQQQQHLQQQINQQQLQQQLQQRLQLQQ-LQHMQHQSQPSPRQHSPVASQ 534
Score = 31.6 bits (70), Expect = 0.72
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 4/58 (6%)
Query: 149 KELVKKQLKKHLSGEEHEKLQQLLQRME-QQEMAQQERKQQQELHLALKQERRAQAQQ 205
+++ ++QL++H + H+++QQ +Q+ Q M Q ++QQQ L + Q++ Q Q
Sbjct: 452 QQMQQQQLQQH---QMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 506
Score = 29.6 bits (65), Expect = 2.7
Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 149 KELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHR 208
+++ ++ ++H + LQQ Q ++QQ + QQ+ +QQ + L L+Q + Q Q
Sbjct: 466 QQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ-INQQQLQQQLQQRLQLQQLQHMQHQSQPS 524
Query: 209 P 209
P
Sbjct: 525 P 525
Score = 29.3 bits (64), Expect = 3.6
Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
++++ ++ + H+ ++ Q L Q++ QQ++ QQ QQ L L Q + Q+Q
Sbjct: 469 QQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ---LQQRLQLQQLQHMQHQSQPSP 525
Query: 208 RPY 210
R +
Sbjct: 526 RQH 528
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/110 (22%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 155 QLKKHLSGEEHEKLQQLLQRMEQQEMAQ--QERKQQQELHLALKQERRAQAQQGHRPYFL 212
Q+ + ++H+ Q Q+ +QQ+M Q Q++ QQ ++H ++Q+ + Q Q H L
Sbjct: 431 QVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHL 490
Query: 213 KKSE---QRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE 259
++ + Q+Q+ + ++L++ +L+ L + ++ R+H P++ +
Sbjct: 491 QQQQQHLQQQINQQQLQQQLQQRLQLQQ-LQHMQHQSQPSPRQHSPVASQ 539
Score = 31.6 bits (70), Expect = 0.72
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 4/58 (6%)
Query: 149 KELVKKQLKKHLSGEEHEKLQQLLQRME-QQEMAQQERKQQQELHLALKQERRAQAQQ 205
+++ ++QL++H + H+++QQ +Q+ Q M Q ++QQQ L + Q++ Q Q
Sbjct: 457 QQMQQQQLQQH---QMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 511
Score = 29.6 bits (65), Expect = 2.7
Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 149 KELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHR 208
+++ ++ ++H + LQQ Q ++QQ + QQ+ +QQ + L L+Q + Q Q
Sbjct: 471 QQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ-INQQQLQQQLQQRLQLQQLQHMQHQSQPS 529
Query: 209 P 209
P
Sbjct: 530 P 530
Score = 29.3 bits (64), Expect = 3.6
Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Query: 148 EKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGH 207
++++ ++ + H+ ++ Q L Q++ QQ++ QQ QQ L L Q + Q+Q
Sbjct: 474 QQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ---LQQRLQLQQLQHMQHQSQPSP 530
Query: 208 RPY 210
R +
Sbjct: 531 RQH 533
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 8/114 (7%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRM-EQQEMAQQERKQQ--QELHLALKQERRAQA 203
++++L +LK EKL+Q +R+ E++ +ERK+Q +E + +E+ +
Sbjct: 755 EDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEE 814
Query: 204 QQGHRPYFLKKSEQRQLA-LAEKFKELK----RSKKLENFLSRKRRRNAGKDRR 252
Q+ LK+ E+R+ A A++ +EL+ R KKLE +KR+R + R
Sbjct: 815 QRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEER 868
Score = 34.7 bits (78), Expect = 0.085
Identities = 30/147 (20%), Positives = 74/147 (50%), Gaps = 12/147 (8%)
Query: 107 RQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHE 166
R + + K AR +++ ++ + ++ + L + + + KE ++++ + EE E
Sbjct: 757 RDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKE--ERRITYYREKEEEE 814
Query: 167 KLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPY--FLKKSEQRQLALAE 224
+ +R E+Q + +ER++++ A ++E + Q+ + +K QR+L + E
Sbjct: 815 Q-----RRAEEQML--KEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEE 867
Query: 225 KFKELKRSKKL-ENFLSRKRRRNAGKD 250
+ + + ++L ++ LSRK R +D
Sbjct: 868 RERRREEERRLGDSSLSRKDSRWGDRD 894
Score = 32.0 bits (71), Expect = 0.55
Identities = 19/91 (20%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
++ KE + ++ E E+L+ L + E++E+ Q+E + Q++ A ++ R +A
Sbjct: 558 LKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQRE-AELQKVRKAEEERLRQEA 616
Query: 204 QQGHRPYFLKKSEQ-RQLALAEKFKELKRSK 233
++ + L++ EQ ++ + E+ +++K+++
Sbjct: 617 KEREKERILQEHEQIKKKTVRERLEQIKKTE 647
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 40.8 bits (94), Expect = 0.001
Identities = 25/108 (23%), Positives = 57/108 (52%), Gaps = 9/108 (8%)
Query: 145 RAKEKELVKKQLKKHLSGEEH-EKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
R +E+E ++ +H + H E+ +Q + E++ +++R++Q+E + ER+ +
Sbjct: 23 RQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRER 82
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDR 251
Q ++ E+++ E+ K+ R +K E +R+R R G++R
Sbjct: 83 Q--------RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
Score = 36.6 bits (83), Expect = 0.022
Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 7/101 (6%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +++E + + + G E +K + + E++ Q+ER++Q +Q R +
Sbjct: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ-------RQRERKRET 154
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
R + ++ E+++ E+ KE K KK E K+R+
Sbjct: 155 DRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 33.1 bits (74), Expect = 0.25
Identities = 22/107 (20%), Positives = 50/107 (46%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +E++ + K+ +E ++ +Q + E++ Q+ER++Q+E +ER
Sbjct: 42 RHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101
Query: 205 QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDR 251
+ + + E+ + E+ K+ +R + E R+R R + R
Sbjct: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQR 148
Score = 31.6 bits (70), Expect = 0.72
Identities = 21/105 (20%), Positives = 48/105 (45%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQG 206
+EKE +++ + E E ++ ++ E+Q +++R+ +E +ER+ + +
Sbjct: 52 REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 207 HRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDR 251
E+ + E+ +E +R ++ E R+R R DR
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDR 156
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/113 (20%), Positives = 49/113 (43%), Gaps = 5/113 (4%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
R +++E ++ ++ + E+ ++ + E+ +ER +Q E ++ER+ Q +
Sbjct: 82 RQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRE 141
Query: 205 -----QGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRR 252
Q R + QR E+ KE K+ +K E +K + +R
Sbjct: 142 RERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 28.5 bits (62), Expect = 6.1
Identities = 17/88 (19%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 166 EKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKS-EQRQLALAE 224
E+ ++ + ++ + ++ER +Q+E ++E R + + HR + E+ + E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 225 KFKELKRSKKLENFLSRKRRRNAGKDRR 252
+ ++ +R ++ E R+R R ++R+
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERK 89
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/100 (29%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Query: 147 KEKELVKKQLKKHLSGEEHEKLQQLLQR-MEQQEMAQQERKQQQELHLALKQERRAQAQQ 205
+++E + KQLK EE EKL++ +R E+ + ++E K+ +E K+E+ + +
Sbjct: 339 RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKA 398
Query: 206 GHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
+ ++ ++RQ AL K +E KR K+ E L + +R
Sbjct: 399 EKQRLKEERRKERQEALEAKLEE-KRKKEEEKRLREEEKR 437
Score = 35.4 bits (80), Expect = 0.050
Identities = 27/107 (25%), Positives = 54/107 (50%), Gaps = 6/107 (5%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQ 204
+ K KE K+ ++ +E EK + +R E++E ++E+ ++Q LK+ERR + Q
Sbjct: 357 KEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQR----LKEERRKERQ 412
Query: 205 QG-HRPYFLKKSEQRQLALAEKFKELKRSK-KLENFLSRKRRRNAGK 249
+ K+ ++ + L E+ K +K K ++ F + + A K
Sbjct: 413 EALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPK 459
Score = 29.3 bits (64), Expect = 3.6
Identities = 25/112 (22%), Positives = 54/112 (48%), Gaps = 11/112 (9%)
Query: 152 VKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYF 211
+ K+ K + + +LQ+ +R+ +Q + ER+++++L K+ + ++
Sbjct: 321 ITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKE 380
Query: 212 LKKSEQR--------QLALAEKFKELKRSKK---LENFLSRKRRRNAGKDRR 252
LK+ E+R + A ++ KE +R ++ LE L KR++ K R
Sbjct: 381 LKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR 432
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 11/121 (9%)
Query: 131 PEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQE 190
P ++ N +R KE E V +QL+ + E ++ L L +R E++ Q+ER ++QE
Sbjct: 156 PSKVEQLQDETNHLR-KELESVGRQLQAEV--ENNQMLSLLNRRQEERLREQEERLREQE 212
Query: 191 LHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEK--------FKELKRSKKLENFLSRK 242
L ++ER + ++ R + EQ +L E+ K+ +R ++ E L R+
Sbjct: 213 ERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERE 272
Query: 243 R 243
R
Sbjct: 273 R 273
Score = 31.6 bits (70), Expect = 0.72
Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 13/77 (16%)
Query: 163 EEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLAL 222
EE EKL + +R E+QE + + E+ L+QER Q + +L
Sbjct: 250 EEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQ-------------QDERLWQ 296
Query: 223 AEKFKELKRSKKLENFL 239
E +EL+R ++LE L
Sbjct: 297 QETLRELERLRELERML 313
Score = 31.2 bits (69), Expect = 0.94
Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 10/111 (9%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQE----------MAQQERKQQQELHLA 194
R + E+ Q+ L+ + E+L++ +R+ +QE Q+ER ++QE L
Sbjct: 178 RQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLC 237
Query: 195 LKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRR 245
+++ Q + L K E+RQ + + ++E L ++R R
Sbjct: 238 EQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERLR 288
Score = 28.1 bits (61), Expect = 8.0
Identities = 22/92 (23%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 144 IRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQA 203
+R +E+ L +++ L G+E +L + ++++ +QE Q+E+++ E L +
Sbjct: 229 LREQEERLCEQE---KLPGQE--RLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLE 283
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKL 235
Q+ R + +Q L E+ +EL+R +L
Sbjct: 284 QERLRQQDERLWQQETLRELERLRELERMLEL 315
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/113 (27%), Positives = 61/113 (53%), Gaps = 19/113 (16%)
Query: 134 FDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHL 193
FD T + L+D K+++L E +KLQ+L Q+ E+Q+ ++E +++Q
Sbjct: 257 FDST-KHLSDASIKKRQL------------ERQKLQELEQQREEQKRREKEAEERQRAEE 303
Query: 194 ALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRS-KKLENFLSRKRRR 245
++E ++ R L+K EQ+Q + +EL+R+ KKLE + ++++
Sbjct: 304 RKQKELEELERERKREEKLRKREQKQ-----RDRELRRNQKKLEKLQAEEQKQ 351
Score = 35.8 bits (81), Expect = 0.038
Identities = 26/100 (26%), Positives = 58/100 (58%), Gaps = 5/100 (5%)
Query: 145 RAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQ-QELHLALKQERRAQA 203
+ +EKE ++Q + +E E+L++ +R ++++ ++E+KQ+ +EL K+ + QA
Sbjct: 289 KRREKEAEERQRAEERKQKELEELER--ERKREEKLRKREQKQRDRELRRNQKKLEKLQA 346
Query: 204 QQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKR 243
++ + K E+R+L LA+ + L+ + + LSR +
Sbjct: 347 EEQKQLQEKIKLEERKLLLAQ--RNLQSIRLIAELLSRAK 384
Score = 33.5 bits (75), Expect = 0.19
Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 22/118 (18%)
Query: 143 DIRAKEKELVK------KQLKKHLSGEEHEKL------------QQLLQRMEQQEMAQQE 184
++R +K+L K KQL++ + EE + L +LL R + ++ +QE
Sbjct: 333 ELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQE 392
Query: 185 RKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRK 242
+K+++ L L+Q+ + Q +++ ++R L L K +EL R + L LS+K
Sbjct: 393 QKEEK---LRLQQQEERRRLQEAELRRVEEEKERALGLQRKEREL-RERLLSILLSKK 446
Score = 31.2 bits (69), Expect = 0.94
Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 26/98 (26%)
Query: 158 KHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQ 217
KHLS +K Q Q++++ E ++E+K+++ K++E+
Sbjct: 261 KHLSDASIKKRQLERQKLQELEQQREEQKRRE-----------------------KEAEE 297
Query: 218 RQLALAEKFK---ELKRSKKLENFLSRKRRRNAGKDRR 252
RQ A K K EL+R +K E L ++ ++ ++ R
Sbjct: 298 RQRAEERKQKELEELERERKREEKLRKREQKQRDRELR 335
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,906,706
Number of Sequences: 37866
Number of extensions: 466859
Number of successful extensions: 9582
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 276
Number of HSP's successfully gapped in prelim test: 494
Number of HSP's that attempted gapping in prelim test: 3841
Number of HSP's gapped (non-prelim): 3105
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.