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Search of human proteins with 24308129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308129 F-box and WD repeat domain containing 5 [Homo
sapiens]
(566 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens] 1158 0.0
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 53 9e-07
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 53 9e-07
gi|19913367 transducin beta-like 1Y [Homo sapiens] 49 9e-06
gi|19913365 transducin beta-like 1Y [Homo sapiens] 49 9e-06
gi|15150805 transducin beta-like 1Y [Homo sapiens] 49 9e-06
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 48 3e-05
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 48 3e-05
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 48 3e-05
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 48 3e-05
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 46 1e-04
gi|31657103 WD repeat domain 23 isoform 1 [Homo sapiens] 45 2e-04
gi|31657101 WD repeat domain 23 isoform 2 [Homo sapiens] 45 2e-04
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 44 3e-04
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 44 4e-04
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 44 5e-04
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 44 5e-04
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 44 5e-04
gi|4757988 WD repeat domain 39 [Homo sapiens] 44 5e-04
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 42 0.002
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 42 0.002
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 42 0.002
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 42 0.002
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 42 0.002
gi|188219762 denticleless homolog [Homo sapiens] 41 0.003
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 40 0.004
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 40 0.004
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 40 0.004
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 40 0.004
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 40 0.006
>gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens]
Length = 566
Score = 1158 bits (2995), Expect = 0.0
Identities = 566/566 (100%), Positives = 566/566 (100%)
Query: 1 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV 60
MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
Sbjct: 1 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV 60
Query: 61 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS 120
PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
Sbjct: 61 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS 120
Query: 121 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL 180
NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
Sbjct: 121 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL 180
Query: 181 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK 240
LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
Sbjct: 181 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK 240
Query: 241 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE 300
IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
Sbjct: 241 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE 300
Query: 301 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY 360
GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
Sbjct: 301 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY 360
Query: 361 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN 420
SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
Sbjct: 361 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN 420
Query: 421 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS 480
SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
Sbjct: 421 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS 480
Query: 481 RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS 540
RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
Sbjct: 481 RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS 540
Query: 541 PRTMRVLQAPRPRPRTFFSWLASQRR 566
PRTMRVLQAPRPRPRTFFSWLASQRR
Sbjct: 541 PRTMRVLQAPRPRPRTFFSWLASQRR 566
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 52.8 bits (125), Expect = 9e-07
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 480 SRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQELLLTASDDATIKAW 538
+ DF+ASG+ED YIW + + +A L H VN V ++PQ ++ +ASDD T++ W
Sbjct: 419 NEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 478
Score = 46.2 bits (108), Expect = 8e-05
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 81 PCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSND---LTISLLHSADMRPYN 137
PC Q L EH ++V FS+ G + A+ SKD TV IW D + LL + + Y
Sbjct: 181 PCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYG 240
Query: 138 WSYTQFSQFNKDDSLLLASG 157
SY +S DD+ L+A G
Sbjct: 241 VSYIAWS---PDDNYLVACG 257
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 52.8 bits (125), Expect = 9e-07
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 480 SRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQELLLTASDDATIKAW 538
+ DF+ASG+ED YIW + + +A L H VN V ++PQ ++ +ASDD T++ W
Sbjct: 435 NEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 494
Score = 46.2 bits (108), Expect = 8e-05
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 81 PCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSND---LTISLLHSADMRPYN 137
PC Q L EH ++V FS+ G + A+ SKD TV IW D + LL + + Y
Sbjct: 197 PCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYG 256
Query: 138 WSYTQFSQFNKDDSLLLASG 157
SY +S DD+ L+A G
Sbjct: 257 VSYIAWS---PDDNYLVACG 273
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS--NDLTISLL--HSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS D + L HS ++ WS
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSP 411
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + S++LAS F
Sbjct: 412 TGPATSNPNSSIMLASASF 430
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 426 ASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW-NTQSG 484
Query: 126 SLLHS 130
SL+HS
Sbjct: 485 SLVHS 489
Score = 30.8 bits (68), Expect = 3.5
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAWRS 540
+AS + D +WD +C L +H++ V SV FSP + + L + S D + W +
Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNT 481
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS--NDLTISLL--HSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS D + L HS ++ WS
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSP 411
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + S++LAS F
Sbjct: 412 TGPATSNPNSSIMLASASF 430
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 426 ASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW-NTQSG 484
Query: 126 SLLHS 130
SL+HS
Sbjct: 485 SLVHS 489
Score = 30.8 bits (68), Expect = 3.5
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAWRS 540
+AS + D +WD +C L +H++ V SV FSP + + L + S D + W +
Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNT 481
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS--NDLTISLL--HSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS D + L HS ++ WS
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSP 411
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + S++LAS F
Sbjct: 412 TGPATSNPNSSIMLASASF 430
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 426 ASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW-NTQSG 484
Query: 126 SLLHS 130
SL+HS
Sbjct: 485 SLVHS 489
Score = 30.8 bits (68), Expect = 3.5
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAWRS 540
+AS + D +WD +C L +H++ V SV FSP + + L + S D + W +
Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNT 481
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISL----LHSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS + + H+ ++ WS
Sbjct: 354 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 413
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + +++LAS F
Sbjct: 414 TGPATSNPNSNIMLASASF 432
Score = 33.5 bits (75), Expect = 0.53
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 428 ASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW-NTQSG 486
Query: 126 SLLHS 130
+L+HS
Sbjct: 487 NLVHS 491
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISL----LHSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS + + H+ ++ WS
Sbjct: 354 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 413
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + +++LAS F
Sbjct: 414 TGPATSNPNSNIMLASASF 432
Score = 33.5 bits (75), Expect = 0.53
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 428 ASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW-NTQSG 486
Query: 126 SLLHS 130
+L+HS
Sbjct: 487 NLVHS 491
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISL----LHSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS + + H+ ++ WS
Sbjct: 405 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 464
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + +++LAS F
Sbjct: 465 TGPATSNPNSNIMLASASF 483
Score = 33.5 bits (75), Expect = 0.53
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 479 ASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW-NTQSG 537
Query: 126 SLLHS 130
+L+HS
Sbjct: 538 NLVHS 542
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISL----LHSADMRPYNWSY 140
V+T + HT++V + + SG ASCS D T+KIWS + + H+ ++ WS
Sbjct: 405 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 464
Query: 141 TQFSQFNKDDSLLLASGVF 159
T + N + +++LAS F
Sbjct: 465 TGPATSNPNSNIMLASASF 483
Score = 33.5 bits (75), Expect = 0.53
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D V TL +H + V ++FS G AS S D V IW N +
Sbjct: 479 ASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW-NTQSG 537
Query: 126 SLLHS 130
+L+HS
Sbjct: 538 NLVHS 542
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 45.8 bits (107), Expect = 1e-04
Identities = 19/34 (55%), Positives = 24/34 (70%)
Query: 86 QTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
+TL+ HTD V +SF HSG ASCS D T+K+W
Sbjct: 144 RTLKGHTDSVQDISFDHSGKLLASCSADMTIKLW 177
Score = 37.4 bits (85), Expect = 0.037
Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
Query: 483 FVASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAW--R 539
F+ SG+ D+ +WD +CL L H++ V V+F + +L+ +DD T++ W +
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFH-SGGKFILSCADDKTLRVWDYK 368
Query: 540 SPRTMRVLQA 549
+ R M+ L A
Sbjct: 369 NKRCMKTLNA 378
>gi|31657103 WD repeat domain 23 isoform 1 [Homo sapiens]
Length = 546
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 468 PNDECFFIF-LDVSRDF--VASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQ 523
P++ F +F + VS D V GA D Y++DR N ++ HED VN+V F+
Sbjct: 261 PDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISS 320
Query: 524 ELLLTASDDATIKAWRSPRTMR 545
++L + DDA K W RTMR
Sbjct: 321 QILFSGGDDAICKVW-DRRTMR 341
>gi|31657101 WD repeat domain 23 isoform 2 [Homo sapiens]
Length = 520
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 468 PNDECFFIF-LDVSRDF--VASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQ 523
P++ F +F + VS D V GA D Y++DR N ++ HED VN+V F+
Sbjct: 235 PDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISS 294
Query: 524 ELLLTASDDATIKAWRSPRTMR 545
++L + DDA K W RTMR
Sbjct: 295 QILFSGGDDAICKVW-DRRTMR 315
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 44.3 bits (103), Expect = 3e-04
Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 8/93 (8%)
Query: 447 VFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLAR 506
V+DL+ + + R L H+A + C F +FVASG++D + +WD C+ R
Sbjct: 89 VWDLEAAK-ILRTLMGHKA----NICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFR 142
Query: 507 LR-HEDVVNSVVFSPQEQELLLTASDDATIKAW 538
R H V + FSP + + L +A+DD T+K W
Sbjct: 143 YRGHSQAVRCLRFSP-DGKWLASAADDHTVKLW 174
Score = 33.5 bits (75), Expect = 0.53
Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 12/100 (12%)
Query: 89 REHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNK 148
R H+ V L FS G AS + D TVK+W DLT + S P + +F+
Sbjct: 144 RGHSQAVRCLRFSPDGKWLASAADDHTVKLW--DLTAGKMMSE--FPGHTGPVNVVEFHP 199
Query: 149 DDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKP 188
++ LLASG SS I L+ F ++S + +P
Sbjct: 200 NE-YLLASG-------SSDRTIRFWDLEKFQVVSCIEGEP 231
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 43.9 bits (102), Expect = 4e-04
Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS----NDLTISLLHSADMRPYNWSY 140
++T + HT++V + + +G ASCS D T+KIWS N + H+ ++ WS
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSP 401
Query: 141 TQFSQFNKDDSLLLASGVF 159
T N + +L+LAS F
Sbjct: 402 TGPGTNNPNANLMLASASF 420
Score = 35.8 bits (81), Expect = 0.11
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 66 AMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTI 125
A + ++ RL+D + + TL +H + V ++FS G AS S D V IW N T
Sbjct: 416 ASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIW-NTQTG 474
Query: 126 SLLHS 130
+L+HS
Sbjct: 475 ALVHS 479
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 43.5 bits (101), Expect = 5e-04
Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 14/126 (11%)
Query: 8 LLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQ----------FYRYYQVA 57
LLP L + L P D+L A CR W+ ++ D LWRE+ + +V
Sbjct: 165 LLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVI 224
Query: 58 RDVPRHPAAMSWYEEFQRLYDTVPCVEVQT---LREHTDQVLHLSFSHSGYQFASCSKDC 114
+ H S Y R+ E+++ L+ H D V+ G + S S D
Sbjct: 225 KPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHVI-TCLQFCGNRIVSGSDDN 283
Query: 115 TVKIWS 120
T+K+WS
Sbjct: 284 TLKVWS 289
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 442 EIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYN 501
+ + V+D++T + L H++ T +++ + + SG D IWD
Sbjct: 442 DTSIRVWDVETGNCIH-TLTGHQSLTSG-------MELKDNILVSGNADSTVKIWDIKTG 493
Query: 502 ICLARL----RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
CL L +H+ V + F+ + ++T+SDD T+K W
Sbjct: 494 QCLQTLQGPNKHQSAVTCLQFN---KNFVITSSDDGTVKLW 531
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 43.5 bits (101), Expect = 5e-04
Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 14/126 (11%)
Query: 8 LLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQ----------FYRYYQVA 57
LLP L + L P D+L A CR W+ ++ D LWRE+ + +V
Sbjct: 283 LLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVI 342
Query: 58 RDVPRHPAAMSWYEEFQRLYDTVPCVEVQT---LREHTDQVLHLSFSHSGYQFASCSKDC 114
+ H S Y R+ E+++ L+ H D V+ G + S S D
Sbjct: 343 KPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHVI-TCLQFCGNRIVSGSDDN 401
Query: 115 TVKIWS 120
T+K+WS
Sbjct: 402 TLKVWS 407
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 442 EIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYN 501
+ + V+D++T + L H++ T +++ + + SG D IWD
Sbjct: 560 DTSIRVWDVETGNCIH-TLTGHQSLTSG-------MELKDNILVSGNADSTVKIWDIKTG 611
Query: 502 ICLARL----RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
CL L +H+ V + F+ + ++T+SDD T+K W
Sbjct: 612 QCLQTLQGPNKHQSAVTCLQFN---KNFVITSSDDGTVKLW 649
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 43.5 bits (101), Expect = 5e-04
Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 14/126 (11%)
Query: 8 LLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQ----------FYRYYQVA 57
LLP L + L P D+L A CR W+ ++ D LWRE+ + +V
Sbjct: 203 LLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVI 262
Query: 58 RDVPRHPAAMSWYEEFQRLYDTVPCVEVQT---LREHTDQVLHLSFSHSGYQFASCSKDC 114
+ H S Y R+ E+++ L+ H D V+ G + S S D
Sbjct: 263 KPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHVI-TCLQFCGNRIVSGSDDN 321
Query: 115 TVKIWS 120
T+K+WS
Sbjct: 322 TLKVWS 327
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 442 EIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYN 501
+ + V+D++T + L H++ T +++ + + SG D IWD
Sbjct: 480 DTSIRVWDVETGNCIH-TLTGHQSLTSG-------MELKDNILVSGNADSTVKIWDIKTG 531
Query: 502 ICLARL----RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
CL L +H+ V + F+ + ++T+SDD T+K W
Sbjct: 532 QCLQTLQGPNKHQSAVTCLQFN---KNFVITSSDDGTVKLW 569
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 12/93 (12%)
Query: 36 WQAVSRDEFLWREQFYRYYQVARDVPRHPA----AMSWYEEFQRLY-----DTVPCVEVQ 86
W+ DE+ + Q + V HP+ A + Y++ +LY D V C
Sbjct: 132 WEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCA--- 188
Query: 87 TLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
TL H V L+F SG + ASCS D TV+IW
Sbjct: 189 TLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 33.9 bits (76), Expect = 0.41
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 9/79 (11%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSND-------LTISLLHSADMRPYN 137
V TL H ++V ++++ SG A+CS+D +V +W D +++ H+ D++
Sbjct: 98 VTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVV 157
Query: 138 WSYTQ--FSQFNKDDSLLL 154
W +Q + + DD++ L
Sbjct: 158 WHPSQELLASASYDDTVKL 176
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 502 ICLARLR-HEDVVNSVVFSPQEQELLLTASDDATIKAWR 539
+C A L HE V S+ F P Q L + SDD T++ WR
Sbjct: 185 VCCATLEGHESTVWSLAFDPSGQRLA-SCSDDRTVRIWR 222
Score = 30.8 bits (68), Expect = 3.5
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 509 HEDVVNSVVFSPQEQELLLTASDDATIKAWRSPR 542
H VN V ++P+E LL + SDD + W+ R
Sbjct: 302 HSQDVNCVAWNPKEPGLLASCSDDGEVAFWKYQR 335
Score = 30.4 bits (67), Expect = 4.5
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 468 PNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYN--ICLARLR--HEDVVNSVVFSPQEQ 523
P+ C+F+ + + +AS DR IW + IC + L H+ V V +SP
Sbjct: 15 PDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPC-G 73
Query: 524 ELLLTASDDATIKAWR 539
L +AS DAT W+
Sbjct: 74 NYLASASFDATTCIWK 89
Score = 29.6 bits (65), Expect = 7.7
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 5/64 (7%)
Query: 480 SRDFVASGAEDRHGYIWD----RHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATI 535
S + +A+ + D+ ++W+ Y H V VV+ P QELL +AS D T+
Sbjct: 116 SGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPS-QELLASASYDDTV 174
Query: 536 KAWR 539
K +R
Sbjct: 175 KLYR 178
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 9/97 (9%)
Query: 449 DLKTMREVRRALRAHRAYTPNDECFFIFLDV---SRDFVASGAEDRHGYIWDRHYNICLA 505
+L R+V + H A P + LD+ + + +G D++ ++D+ LA
Sbjct: 203 ELSKYRQVASHVGLHSASIPG----ILALDLCPSDTNKILTGGADKNVVVFDKSSEQILA 258
Query: 506 RLR-HEDVVNSVVFSPQEQELLLTASDDATIKAWRSP 541
L+ H V SVVF P Q+L+ +AS DATI+ W P
Sbjct: 259 TLKGHTKKVTSVVFHPS-QDLVFSASPDATIRIWSVP 294
Score = 32.0 bits (71), Expect = 1.6
Identities = 12/45 (26%), Positives = 24/45 (53%)
Query: 75 RLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
+++D V H+ + ++FS +GY A+ + D +VK+W
Sbjct: 375 KIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 17/84 (20%)
Query: 9 LPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFY---------------RY 53
LPD +V +IF L D+ A VC+++ ++ D LW+ + ++
Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKF 134
Query: 54 YQVARDVPRHPAAMSWYEEFQRLY 77
YQ+ + HP W E FQ+LY
Sbjct: 135 YQINPEEYEHP--NPWKESFQQLY 156
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 17/84 (20%)
Query: 9 LPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFY---------------RY 53
LPD +V +IF L D+ A VC+++ ++ D LW+ + ++
Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKF 134
Query: 54 YQVARDVPRHPAAMSWYEEFQRLY 77
YQ+ + HP W E FQ+LY
Sbjct: 135 YQINPEEYEHP--NPWKESFQQLY 156
>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
Length = 585
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 17/84 (20%)
Query: 9 LPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFY---------------RY 53
LPD +V +IF L D+ A VC+++ ++ D LW+ + ++
Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKF 134
Query: 54 YQVARDVPRHPAAMSWYEEFQRLY 77
YQ+ + HP W E FQ+LY
Sbjct: 135 YQINPEEYEHP--NPWKESFQQLY 156
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 472 CFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQELLLTAS 530
C + + ++ SGA+DR IWD C+ L H V+ F P E +++T S
Sbjct: 190 CIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHP-ELPIIITGS 248
Query: 531 DDATIKAWRS 540
+D T++ W S
Sbjct: 249 EDGTVRIWHS 258
Score = 35.4 bits (80), Expect = 0.14
Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 440 AEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDR--HGYIWD 497
A+++ + VF+ T+ V AH Y C I + ++ F+ + ++D + WD
Sbjct: 76 ADDMQIRVFNYNTLERVHM-FEAHSDYI---RC--IAVHPTQPFILTSSDDMLIKLWDWD 129
Query: 498 RHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWR 539
+ ++ H V +V +P++ +AS D TIK W+
Sbjct: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQ 171
>gi|188219762 denticleless homolog [Homo sapiens]
Length = 730
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 473 FFIFLDVSRD--FVASGAEDRHGYIW--DRHYNICLARLRHEDVVNSVVFSPQEQELLLT 528
F++ +S D F+ SG+ D YIW + L H V SV + P + + T
Sbjct: 319 FYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIAT 378
Query: 529 ASDDATIKAWRSPR 542
SDD T+K WR R
Sbjct: 379 CSDDNTLKIWRLNR 392
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 40.4 bits (93), Expect = 0.004
Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFN 147
++ H D+VL +FS A+CS D VKIW N +T L+H+ D + F+ N
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIW-NSMTGELVHTYDEHSEQVNCCHFT--N 709
Query: 148 KDDSLLLASG 157
LLLA+G
Sbjct: 710 SSHHLLLATG 719
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 91 HTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDD 150
H VL SH +F+S S D T KIWS DL LL ++R +N + S F+ D
Sbjct: 1041 HQGTVLSCDISHDATKFSSTSADKTAKIWSFDL---LLPLHELRGHN-GCVRCSAFSV-D 1095
Query: 151 SLLLASGVFLGPHNSSSGEIAVISLDSFALL---SRVRNKPYDVFGCWLTE 198
S LLA+G +GEI + ++ + LL + + + G W+T+
Sbjct: 1096 STLLATG-------DDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Score = 35.4 bits (80), Expect = 0.14
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLL 128
+R HTD V H FS G + ASC D T++++ + LL
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLL 651
Score = 33.1 bits (74), Expect = 0.70
Identities = 18/47 (38%), Positives = 24/47 (51%)
Query: 73 FQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
F +L+D T+ HT+ V H FS ASCS D T+K+W
Sbjct: 724 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
+A+G+ D +WD + C + H + VN FSP ++ LL + S D T+K W
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK-LLASCSADGTLKLW 770
Score = 30.4 bits (67), Expect = 4.5
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 12/74 (16%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQF--ASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYT- 141
V T EH++QV F++S + A+ S DC +K+W L+ + R + +T
Sbjct: 692 VHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWD-------LNQKECRNTMFGHTN 744
Query: 142 --QFSQFNKDDSLL 153
+F+ DD LL
Sbjct: 745 SVNHCRFSPDDKLL 758
Score = 30.4 bits (67), Expect = 4.5
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 494 YIWDRHYNICLARLR-HEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMR 545
++W+ +A R H V+ V+FSP L T+SDD TI+ W + + +
Sbjct: 822 FLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL-TSSDDQTIRLWETKKVCK 873
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 40.4 bits (93), Expect = 0.004
Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFN 147
++ H D+VL +FS A+CS D VKIW N +T L+H+ D + F+ N
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIW-NSMTGELVHTYDEHSEQVNCCHFT--N 709
Query: 148 KDDSLLLASG 157
LLLA+G
Sbjct: 710 SSHHLLLATG 719
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 91 HTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDD 150
H VL SH +F+S S D T KIWS DL LL ++R +N + S F+ D
Sbjct: 1084 HQGTVLSCDISHDATKFSSTSADKTAKIWSFDL---LLPLHELRGHN-GCVRCSAFSV-D 1138
Query: 151 SLLLASGVFLGPHNSSSGEIAVISLDSFALL---SRVRNKPYDVFGCWLTE 198
S LLA+G +GEI + ++ + LL + + + G W+T+
Sbjct: 1139 STLLATG-------DDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1182
Score = 35.4 bits (80), Expect = 0.14
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLL 128
+R HTD V H FS G + ASC D T++++ + LL
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLL 651
Score = 33.1 bits (74), Expect = 0.70
Identities = 18/47 (38%), Positives = 24/47 (51%)
Query: 73 FQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
F +L+D T+ HT+ V H FS ASCS D T+K+W
Sbjct: 724 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
+A+G+ D +WD + C + H + VN FSP ++ LL + S D T+K W
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK-LLASCSADGTLKLW 770
Score = 30.4 bits (67), Expect = 4.5
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 12/74 (16%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQF--ASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYT- 141
V T EH++QV F++S + A+ S DC +K+W L+ + R + +T
Sbjct: 692 VHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWD-------LNQKECRNTMFGHTN 744
Query: 142 --QFSQFNKDDSLL 153
+F+ DD LL
Sbjct: 745 SVNHCRFSPDDKLL 758
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 40.4 bits (93), Expect = 0.004
Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFN 147
++ H D+VL +FS A+CS D VKIW N +T L+H+ D + F+ N
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIW-NSMTGELVHTYDEHSEQVNCCHFT--N 698
Query: 148 KDDSLLLASG 157
LLLA+G
Sbjct: 699 SSHHLLLATG 708
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 91 HTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDD 150
H VL SH +F+S S D T KIWS DL LL ++R +N + S F+ D
Sbjct: 1030 HQGTVLSCDISHDATKFSSTSADKTAKIWSFDL---LLPLHELRGHN-GCVRCSAFSV-D 1084
Query: 151 SLLLASGVFLGPHNSSSGEIAVISLDSFALL---SRVRNKPYDVFGCWLTE 198
S LLA+G +GEI + ++ + LL + + + G W+T+
Sbjct: 1085 STLLATG-------DDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1128
Score = 35.4 bits (80), Expect = 0.14
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLL 128
+R HTD V H FS G + ASC D T++++ + LL
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLL 640
Score = 33.1 bits (74), Expect = 0.70
Identities = 18/47 (38%), Positives = 24/47 (51%)
Query: 73 FQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
F +L+D T+ HT+ V H FS ASCS D T+K+W
Sbjct: 713 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 759
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
+A+G+ D +WD + C + H + VN FSP ++ LL + S D T+K W
Sbjct: 705 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK-LLASCSADGTLKLW 759
Score = 30.4 bits (67), Expect = 4.5
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 12/74 (16%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQF--ASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYT- 141
V T EH++QV F++S + A+ S DC +K+W L+ + R + +T
Sbjct: 681 VHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWD-------LNQKECRNTMFGHTN 733
Query: 142 --QFSQFNKDDSLL 153
+F+ DD LL
Sbjct: 734 SVNHCRFSPDDKLL 747
Score = 30.4 bits (67), Expect = 4.5
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 494 YIWDRHYNICLARLR-HEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMR 545
++W+ +A R H V+ V+FSP L T+SDD TI+ W + + +
Sbjct: 811 FLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL-TSSDDQTIRLWETKKVCK 862
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 40.4 bits (93), Expect = 0.004
Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFN 147
++ H D+VL +FS A+CS D VKIW N +T L+H+ D + F+ N
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIW-NSMTGELVHTYDEHSEQVNCCHFT--N 698
Query: 148 KDDSLLLASG 157
LLLA+G
Sbjct: 699 SSHHLLLATG 708
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 91 HTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDD 150
H VL SH +F+S S D T KIWS DL LL ++R +N + S F+ D
Sbjct: 1073 HQGTVLSCDISHDATKFSSTSADKTAKIWSFDL---LLPLHELRGHN-GCVRCSAFSV-D 1127
Query: 151 SLLLASGVFLGPHNSSSGEIAVISLDSFALL---SRVRNKPYDVFGCWLTE 198
S LLA+G +GEI + ++ + LL + + + G W+T+
Sbjct: 1128 STLLATG-------DDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1171
Score = 35.4 bits (80), Expect = 0.14
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 88 LREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLL 128
+R HTD V H FS G + ASC D T++++ + LL
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLL 640
Score = 33.1 bits (74), Expect = 0.70
Identities = 18/47 (38%), Positives = 24/47 (51%)
Query: 73 FQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIW 119
F +L+D T+ HT+ V H FS ASCS D T+K+W
Sbjct: 713 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 759
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 484 VASGAEDRHGYIWDRHYNICLARL-RHEDVVNSVVFSPQEQELLLTASDDATIKAW 538
+A+G+ D +WD + C + H + VN FSP ++ LL + S D T+K W
Sbjct: 705 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDK-LLASCSADGTLKLW 759
Score = 30.4 bits (67), Expect = 4.5
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 12/74 (16%)
Query: 85 VQTLREHTDQVLHLSFSHSGYQF--ASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYT- 141
V T EH++QV F++S + A+ S DC +K+W L+ + R + +T
Sbjct: 681 VHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWD-------LNQKECRNTMFGHTN 733
Query: 142 --QFSQFNKDDSLL 153
+F+ DD LL
Sbjct: 734 SVNHCRFSPDDKLL 747
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 478 DVSRDFVASGAEDRHGYIWDRHYNICLARLR-HEDVVNSVVFSPQEQELLLTASDDATIK 536
DVS +A+G D IW+ + L L H+DVV + F+P +L++AS D T++
Sbjct: 120 DVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLR 179
Query: 537 AW 538
W
Sbjct: 180 IW 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,116,533
Number of Sequences: 37866
Number of extensions: 1040696
Number of successful extensions: 3041
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2495
Number of HSP's gapped (non-prelim): 602
length of query: 566
length of database: 18,247,518
effective HSP length: 108
effective length of query: 458
effective length of database: 14,157,990
effective search space: 6484359420
effective search space used: 6484359420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.