Search of human proteins with 24308115

Search of human proteins with 24308115

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24308115 interferon regulatory factor 2 binding protein 1
[Homo sapiens]
         (584 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho...  1205   0.0  
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]         417   e-116
gi|116734704 interferon regulatory factor 2 binding protein 2 is...   254   1e-67
gi|116734706 interferon regulatory factor 2 binding protein 2 is...   192   5e-49
gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]    51   3e-06
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]    51   3e-06
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]    51   3e-06
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    49   1e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    48   2e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    48   2e-05
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s...    45   1e-04
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo...    45   1e-04
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             45   1e-04
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    45   2e-04
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|33589824 cell growth regulator with EF-hand domain 1 [Homo sa...    44   3e-04
gi|55750053 atrophin-1 [Homo sapiens]                                  44   4e-04
gi|55750041 atrophin-1 [Homo sapiens]                                  44   4e-04
gi|122937424 one cut homeobox 3 [Homo sapiens]                         44   4e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  44   5e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     44   5e-04
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     44   5e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    43   0.001
gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]            42   0.001
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    42   0.001
gi|22779860 forkhead box L1 [Homo sapiens]                             42   0.001
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    42   0.002
gi|150170670 piccolo isoform 2 [Homo sapiens]                          42   0.002

>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
           sapiens]
          Length = 584

 Score = 1205 bits (3117), Expect = 0.0
 Identities = 584/584 (100%), Positives = 584/584 (100%)

Query: 1   MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHV 60
           MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHV
Sbjct: 1   MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHV 60

Query: 61  LPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGR 120
           LPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGR
Sbjct: 61  LPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGR 120

Query: 121 LPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSGLGSRGLT 180
           LPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSGLGSRGLT
Sbjct: 121 LPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSGLGSRGLT 180

Query: 181 LAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACA 240
           LAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACA
Sbjct: 181 LAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACA 240

Query: 241 PFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDA 300
           PFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDA
Sbjct: 241 PFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDA 300

Query: 301 LREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA 360
           LREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA
Sbjct: 301 LREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA 360

Query: 361 ALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVP 420
           ALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVP
Sbjct: 361 ALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVP 420

Query: 421 SPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPT 480
           SPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPT
Sbjct: 421 SPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPT 480

Query: 481 AGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGP 540
           AGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGP
Sbjct: 481 AGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGP 540

Query: 541 AGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP 584
           AGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP
Sbjct: 541 AGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP 584


>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
          Length = 796

 Score =  417 bits (1072), Expect = e-116
 Identities = 270/606 (44%), Positives = 338/606 (55%), Gaps = 105/606 (17%)

Query: 68  GPPALKHPATKDLAAAAA----QGPQLPPPQAQPQPSGTGG-------GVSGQDRYDRAT 116
           GPP L   +    +AAA+    +G         P P G GG        +  Q   +   
Sbjct: 207 GPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPA 266

Query: 117 SSGRLPLPSPALEYTLGSRLANGLGREEAVAEGARR--ALLGSMPGLMPPGLLAAAVSGL 174
           S+  LP P P   + LGSR     G       GA    A LG  PG+      ++A S  
Sbjct: 267 SAAVLPPPPP---HALGSR-----GPPTPAPPGAPGGPACLGGTPGVSATS--SSASSST 316

Query: 175 GSRGLTLAPGLSPARP--LFGSDFEKE--KQQRNADCLAELNEAMRGRAEEWHGRPKAVR 230
            S    +  G    RP  +  +D E+E  ++QRNA+ LAEL+E++R RAEEW  +PK VR
Sbjct: 317 SSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWASKPKMVR 376

Query: 231 EQLLALSACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVL 290
           + LL L+ C P+ VRFKKDH L+GRVFAFDA ++P G ++ELKLF EYP GSGNVY+   
Sbjct: 377 DTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKP-GMDYELKLFIEYPTGSGNVYSSAS 435

Query: 291 AVARQMFHDALREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAP-AEA 349
            VA+QM+ D +++ G+ L SSGFKYLEYE++HGSG+WR LG+LL + VR F+E  P A+ 
Sbjct: 436 GVAKQMYQDCMKDFGRGL-SSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADM 494

Query: 350 LPQQYPEP--------------APAALCGP---PPRAPS-RNLAPTPRRRKASPEPEGEA 391
           LPQ Y +               AP+A  G    PP APS R  A + R+RKASPEP   A
Sbjct: 495 LPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSA 554

Query: 392 AGKMTT-EEQQQRHWVA------------------------------PGGPYSAETP--- 417
            G +   EEQQ++ W+A                              P GP+S  T    
Sbjct: 555 EGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPE 614

Query: 418 ----GVPSPIAALKNVAEALG--HSPKDPGGGGGPVRAGGASPAASST-----AQPPTQH 466
                 PSP+AAL +VA+ LG  HSPKD    G  V +  AS   +S+     A  P Q 
Sbjct: 615 SAPQNGPSPMAALMSVADTLGTAHSPKD----GSSVHSTTASARRNSSSPVSPASVPGQR 670

Query: 467 RLVARNGEAEVSPTAGAEAVSGGGS--------GTGATPGAPLCCTLCRERLEDTHFVQC 518
           RL +RNG+  +       +   G           +      PLCCT+C ERLEDTHFVQC
Sbjct: 671 RLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQC 730

Query: 519 PSVPGHKFCFPCSREFIKAQGPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKV 578
           PSVP HKFCFPCSRE IKAQG  GEVYCPSG+KCPLVGS+VPWAFMQGEIATILAGD+KV
Sbjct: 731 PSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKV 790

Query: 579 KKERDP 584
           KKERDP
Sbjct: 791 KKERDP 796



 Score =  123 bits (309), Expect = 4e-28
 Identities = 75/167 (44%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 2   ASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSH-V 60
           A V +SRRQ CYLCDLP+MPWAM+WDFSE VCRGCVN+EGADRIE +I+ ARQLKR+H  
Sbjct: 4   AQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGC 63

Query: 61  LPEGRSPGPP--------------ALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGV 106
             +GRSPGPP              A    A    AAAAAQ  Q    Q Q Q        
Sbjct: 64  FQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQ 123

Query: 107 SGQ--DRYDRATSSGRLPLPSPALEYTLGSRLANGLGREEAVAEGAR 151
             Q  +  D ++    L  PS    Y L +  A       AV + +R
Sbjct: 124 QQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSR 170


>gi|116734704 interferon regulatory factor 2 binding protein 2
           isoform A [Homo sapiens]
          Length = 587

 Score =  254 bits (650), Expect = 1e-67
 Identities = 231/672 (34%), Positives = 292/672 (43%), Gaps = 179/672 (26%)

Query: 1   MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSH- 59
           +A   ASRRQ CYLCDLP+MPWAM+WDF+E VCRGCVN+EGADR+E +I+ ARQLKR+H 
Sbjct: 5   VAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHG 64

Query: 60  VLPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQ---AQPQPSGTGG------GVSGQD 110
             PEGRSP   A         A+AAA+ P L        Q Q  G GG           +
Sbjct: 65  CFPEGRSPPGAA---------ASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALE 115

Query: 111 RYDRATSSGRLPL-----------------PSPALEYTLGSRLANGLGREEAVAEGARRA 153
           RY  A ++ R P                  P+P      G  + NG  + E   E  R++
Sbjct: 116 RYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQS 175

Query: 154 ------------LLGSMPGLMPP-----GLLAAAVSGLGSRGLTLAPGLSPARPL----- 191
                       L+  M G   P     GL   A + L +   T A  L  A+P      
Sbjct: 176 PNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAH 235

Query: 192 -----FGSDFEKEKQQRN----------------ADCL------AELNEAMRGRA----- 219
                  S    E +QR                 AD L      AEL+    G++     
Sbjct: 236 KRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGE 295

Query: 220 EEWHGRPKAVREQLLAL---SACAPFNVRFKKDHGL-VGRVFAFDATARPPGYEFELKLF 275
           ++W  RPK VR+ LLAL       PF  +FKK+  L  GR+  F+A              
Sbjct: 296 QDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEA-------------- 341

Query: 276 TEYPCGSGNVYAGVLAVARQMFHDALREPGKALASSGFKYLEYERRHG----SGEWRQLG 331
                   N   G  AVAR       R+P            E E   G    +GE +   
Sbjct: 342 --------NGANGSKAVARTA---RKRKPSP----------EPEGEVGPPKINGEAQPWL 380

Query: 332 ELLTDGVRSFREPAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEA 391
              T+G++    P  +   P   P  +P +    PP A     +P      A       A
Sbjct: 381 STSTEGLKIPMTPTSSFVSPPP-PTASPHSNRTTPPEAAQNGQSP----MAALILVADNA 435

Query: 392 AGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGG 451
            G   +++  Q H        ++ +P  PS +   +     LG  P++ GG G     GG
Sbjct: 436 GGSHASKDANQVHSTT---RRNSNSPPSPSSMNQRR-----LG--PREVGGQGAG-NTGG 484

Query: 452 ASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPGAPLCCTLCRERLE 511
             P                      V P     ++      T A     LC     ERLE
Sbjct: 485 LEP----------------------VHPA----SLPDSSLATSAPLCCTLC----HERLE 514

Query: 512 DTHFVQCPSVPGHKFCFPCSREFIKAQGPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATI 571
           DTHFVQCPSVP HKFCFPCSR+ IK QG +GEVYCPSG+KCPLVGS+VPWAFMQGEIATI
Sbjct: 515 DTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATI 574

Query: 572 LAGDIKVKKERD 583
           LAGD+KVKKERD
Sbjct: 575 LAGDVKVKKERD 586


>gi|116734706 interferon regulatory factor 2 binding protein 2
           isoform B [Homo sapiens]
          Length = 571

 Score =  192 bits (489), Expect = 5e-49
 Identities = 118/240 (49%), Positives = 134/240 (55%), Gaps = 33/240 (13%)

Query: 374 LAPTPRRRKASPEPEGEAAGKMTTEEQQQ----------------RHWVAP----GGPYS 413
           +A T R+RK SPEPEGE        E Q                   +V+P      P+S
Sbjct: 334 VARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHS 393

Query: 414 AETP------GVPSPIAALKNVAEALG--HSPKDPGGGGGPVRAGGASPAASSTAQPPTQ 465
             T          SP+AAL  VA+  G  H+ KD        R    SP + S+     Q
Sbjct: 394 NRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMN---Q 450

Query: 466 HRLVARN-GEAEVSPTAGAEAVSGGG-SGTGATPGAPLCCTLCRERLEDTHFVQCPSVPG 523
            RL  R  G      T G E V       +     APLCCTLC ERLEDTHFVQCPSVP 
Sbjct: 451 RRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPS 510

Query: 524 HKFCFPCSREFIKAQGPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERD 583
           HKFCFPCSR+ IK QG +GEVYCPSG+KCPLVGS+VPWAFMQGEIATILAGD+KVKKERD
Sbjct: 511 HKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERD 570



 Score =  129 bits (323), Expect = 1e-29
 Identities = 120/355 (33%), Positives = 152/355 (42%), Gaps = 95/355 (26%)

Query: 1   MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSH- 59
           +A   ASRRQ CYLCDLP+MPWAM+WDF+E VCRGCVN+EGADR+E +I+ ARQLKR+H 
Sbjct: 5   VAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHG 64

Query: 60  VLPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQ---AQPQPSGTGG------GVSGQD 110
             PEGRSP   A         A+AAA+ P L        Q Q  G GG           +
Sbjct: 65  CFPEGRSPPGAA---------ASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALE 115

Query: 111 RYDRATSSGRLPL-----------------PSPALEYTLGSRLANGLGREEAVAEGARRA 153
           RY  A ++ R P                  P+P      G  + NG  + E   E  R++
Sbjct: 116 RYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQS 175

Query: 154 ------------LLGSMPGLMPP-----GLLAAAVSGLGSRGLTLAPGLSPARPL----- 191
                       L+  M G   P     GL   A + L +   T A  L  A+P      
Sbjct: 176 PNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAH 235

Query: 192 -----FGSDFEKEKQQRN----------------ADCL------AELNEAMRGRA----- 219
                  S    E +QR                 AD L      AEL+    G++     
Sbjct: 236 KRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGE 295

Query: 220 EEWHGRPKAVREQLLAL---SACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFE 271
           ++W  RPK VR+ LLAL       PF  +FKK+  L     A  A  R P  E E
Sbjct: 296 QDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALT--AVARTARKRKPSPEPE 348


>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
          Length = 170

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 41/109 (37%), Positives = 45/109 (41%), Gaps = 15/109 (13%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403
           P PA A P+  P   PA   G P  APSR  AP P    A PE  GE AG     E    
Sbjct: 35  PEPARAPPEPAP---PAEATGAP--APSRPCAPEPAASPAGPEEPGEPAGLGELGE---- 85

Query: 404 HWVAPGGPYSAETPGVP--SPIAALKNVAEALGHSPKDPGGGGGPVRAG 450
               P GP   E PG P  +P  A +   EA     +D  G  GP   G
Sbjct: 86  ----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 375 APTPRRRKASPEPEGEAAGKMTTEEQ-QQRHWVAPGGPYSAETPGVPSPIAALKNVAEAL 433
           +P P R    P P  EA G              +P GP   E PG P   A L  + E  
Sbjct: 34  SPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP---EEPGEP---AGLGELGEPA 87

Query: 434 GHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGT 493
           G  P +P G G P  A   +   +  A+   +  L    G +    + G E   G G   
Sbjct: 88  G--PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS----SEGPEEEDGEGFSF 141

Query: 494 GATPG 498
             +PG
Sbjct: 142 KYSPG 146


>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
          Length = 177

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 41/109 (37%), Positives = 45/109 (41%), Gaps = 15/109 (13%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403
           P PA A P+  P   PA   G P  APSR  AP P    A PE  GE AG     E    
Sbjct: 35  PEPARAPPEPAP---PAEATGAP--APSRPCAPEPAASPAGPEEPGEPAGLGELGE---- 85

Query: 404 HWVAPGGPYSAETPGVP--SPIAALKNVAEALGHSPKDPGGGGGPVRAG 450
               P GP   E PG P  +P  A +   EA     +D  G  GP   G
Sbjct: 86  ----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 375 APTPRRRKASPEPEGEAAGKMTTEEQ-QQRHWVAPGGPYSAETPGVPSPIAALKNVAEAL 433
           +P P R    P P  EA G              +P GP   E PG P   A L  + E  
Sbjct: 34  SPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP---EEPGEP---AGLGELGEPA 87

Query: 434 GHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGT 493
           G  P +P G G P  A   +   +  A+   +  L    G +    + G E   G G   
Sbjct: 88  G--PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS----SEGPEEEDGEGFSF 141

Query: 494 GATPG 498
             +PG
Sbjct: 142 KYSPG 146


>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
          Length = 204

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 41/109 (37%), Positives = 45/109 (41%), Gaps = 15/109 (13%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403
           P PA A P+  P   PA   G P  APSR  AP P    A PE  GE AG     E    
Sbjct: 35  PEPARAPPEPAP---PAEATGAP--APSRPCAPEPAASPAGPEEPGEPAGLGELGE---- 85

Query: 404 HWVAPGGPYSAETPGVP--SPIAALKNVAEALGHSPKDPGGGGGPVRAG 450
               P GP   E PG P  +P  A +   EA     +D  G  GP   G
Sbjct: 86  ----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 375 APTPRRRKASPEPEGEAAGKMTTEEQ-QQRHWVAPGGPYSAETPGVPSPIAALKNVAEAL 433
           +P P R    P P  EA G              +P GP   E PG P   A L  + E  
Sbjct: 34  SPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP---EEPGEP---AGLGELGEPA 87

Query: 434 GHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGT 493
           G  P +P G G P  A   +   +  A+   +  L    G +    + G E   G G   
Sbjct: 88  G--PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS----SEGPEEEDGEGFSF 141

Query: 494 GATPG 498
             +PG
Sbjct: 142 KYSPG 146


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase [Homo sapiens]
          Length = 1327

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/174 (27%), Positives = 67/174 (38%), Gaps = 32/174 (18%)

Query: 352 QQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVA-PGG 410
           QQ  +PAP A   PPP  P  +    P    ASP   G A           RH +A P G
Sbjct: 15  QQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFA------SPRHGLALPEG 68

Query: 411 PYSAETPGVP-----------------------SPIAALKNVAEALGHSPKDPGGGGGPV 447
             S + P  P                       +P+    + + A G +P   G G    
Sbjct: 69  DGSRDPPDRPRSPDPVDGTSCCSTTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNS 128

Query: 448 RAGGASPAASSTAQPPTQHRLVARNGEAE-VSPTAG-AEAVSGGGSGTGATPGA 499
            +  +SP +SS++ P +    +A + EA  VS TA      +G G+G  A  GA
Sbjct: 129 PSSSSSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVSGA 182


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 58/175 (33%), Positives = 63/175 (36%), Gaps = 36/175 (20%)

Query: 345 APAEALPQQYPEPAPAALC----------GPP-PRAPSRNLAPTPRRRKASPEPEGEAAG 393
           APAE  P   PEP PA             GPP PR P     P P   K  P PEG A  
Sbjct: 77  APAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS 136

Query: 394 KMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSP-KDPGGGGGPVRAGGA 452
                       VA G   +   P  P+  AAL   A   G  P   PG G GP     A
Sbjct: 137 CAPVPAAAA---VAAGPEPAPAGPAKPAGPAAL---AARAGPGPGPGPGPGPGPGPGKPA 190

Query: 453 SPAASSTAQPPTQHRLVARNGEAEV--SPTAGAEAVSGGGSGTGA-----TPGAP 500
            P A+ T            NG A +  S  A A AVS   +G  A      P AP
Sbjct: 191 GPGAAQTL-----------NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/153 (26%), Positives = 52/153 (33%), Gaps = 30/153 (19%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403
           PAPA   P   P PA  A   PPP      LA  P                         
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGH----------------------- 286

Query: 404 HWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPP 463
               P GP +A  P VP P AA +N   A G +P      GGP    G     ++ A P 
Sbjct: 287 ----PAGPPTA-APAVPPP-AAAQNGGSA-GAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339

Query: 464 TQHRLVARNGEAEVSPTAGAEAVSGGGSGTGAT 496
              +  +     + +P A     + G + T A+
Sbjct: 340 PGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 45/177 (25%), Positives = 56/177 (31%), Gaps = 23/177 (12%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRA-------PSRNLAPTPRRRKASPEPEGEAAGKMT 396
           P PA A     PEPAPA    P   A       P     P P       +P G  A +  
Sbjct: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198

Query: 397 TEEQ---QQRHWVAPG------GPYSA-ETPGVPSPIAALKNVAEALGHSPKDPGGGGGP 446
                     H  AP       GP +    P   +P   ++        +P  P     P
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP 258

Query: 447 VRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAG------AEAVSGGGSGTGATP 497
                A+PAA+    PP    L    G     PTA       A A +GG +G    P
Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 32/121 (26%), Positives = 41/121 (33%), Gaps = 11/121 (9%)

Query: 384 SPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGG 443
           +PE    AAG +          V  G P  A   G  +P       A     + +   GG
Sbjct: 47  TPEVRAAAAGALGNH-------VVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG 99

Query: 444 GGPVRAGGASP----AASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPGA 499
           GGP R G  SP      +  A P  + R          +P   A AV+ G     A P  
Sbjct: 100 GGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK 159

Query: 500 P 500
           P
Sbjct: 160 P 160



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 47/189 (24%), Positives = 57/189 (30%), Gaps = 33/189 (17%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQ- 402
           P+P   L    P P PAA   PPP   + + AP P     +  PE   AG          
Sbjct: 108 PSPRRPLVPAGPAP-PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL 166

Query: 403 --RHWVAPG---GPYSAETPGVPS-----------------------PIAALKNVAEALG 434
             R    PG   GP     PG P+                        ++ + N   AL 
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL 226

Query: 435 HSPKDPGGGG---GPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGS 491
             PK    G     P   G A+P A +   PP      A        P A A      G 
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGH 286

Query: 492 GTGATPGAP 500
             G    AP
Sbjct: 287 PAGPPTAAP 295



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 36/127 (28%), Positives = 43/127 (33%), Gaps = 9/127 (7%)

Query: 67  PGPPALKHPATKDLAAAAAQGPQLPP-PQAQPQPSGTGGG-------VSGQDRYDRATSS 118
           P P A   PA    AA AA  P  PP P    +P G   G       V          S+
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA 309

Query: 119 GRLPLPSPALEYTLGSRLANGLGREEAV-AEGARRALLGSMPGLMPPGLLAAAVSGLGSR 177
           G  P P+PA     G     G G   A  A G +      +    PP     A SG  S 
Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST 369

Query: 178 GLTLAPG 184
             ++  G
Sbjct: 370 AASMVIG 376



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/138 (26%), Positives = 51/138 (36%), Gaps = 22/138 (15%)

Query: 67  PGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGRLPLPS- 125
           PGPP+ + P           GP  P  + +P P G+ G  +       A ++G  P P+ 
Sbjct: 105 PGPPSPRRPLVP-------AGPAPPAAKLRPPPEGSAGSCAPVPAA-AAVAAGPEPAPAG 156

Query: 126 ---PALEYTLGSRLANGLGRE----------EAVAEGARRALLGSMPGLMPPGLLAAAVS 172
              PA    L +R   G G            +    GA + L GS   L      A AVS
Sbjct: 157 PAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVS 216

Query: 173 GLGSRGLTLAPGLSPARP 190
            + +    L P   PA P
Sbjct: 217 LVNNGPAALLPLPKPAAP 234


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 36/123 (29%), Positives = 41/123 (33%), Gaps = 17/123 (13%)

Query: 345 APAEALPQQYPEPAPAALCGPP----PRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQ 400
           AP  + P   P P PA    PP    P  PS  +  TP +    P P     G     +Q
Sbjct: 141 APPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ 200

Query: 401 QQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTA 460
                  PGGP   + PG P P           G     PGG   P   GG  P      
Sbjct: 201 GP----GPGGPKGGKMPGGPKPGG---------GPGLSTPGGHPKPPHRGGGEPRGGRQH 247

Query: 461 QPP 463
            PP
Sbjct: 248 HPP 250



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 52/187 (27%), Positives = 69/187 (36%), Gaps = 43/187 (22%)

Query: 323 GSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA-ALCGPPPRAPSRNLAPTPRRR 381
           G G  R+ G     G+  FR P P   L Q      P     GP P  P     P P ++
Sbjct: 13  GGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPP----PPPHQQ 68

Query: 382 KASPEPEGEAAGKMTTEEQQQRHWVAPGG-PYSAETPGVPSPIAALKNVAEALGHSPKDP 440
           +  P P+          +Q   H   P   P+  + P  P   ++   VA+         
Sbjct: 69  QQQPPPQ------QPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQ--------- 113

Query: 441 GGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGG-------SGT 493
             G GP    G++P ASS+A P T              PT+GA   SG G       + T
Sbjct: 114 --GPGPAPGVGSAPPASSSAPPAT-------------PPTSGAPPGSGPGPTPTPPPAVT 158

Query: 494 GATPGAP 500
            A PGAP
Sbjct: 159 SAPPGAP 165



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/140 (26%), Positives = 41/140 (29%), Gaps = 23/140 (16%)

Query: 344 PAP----AEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKA---SPEPEGEAAGKMT 396
           PAP    A       P   P     PP   P     P P    A   +P P   ++G  T
Sbjct: 117 PAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPT 176

Query: 397 TEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAA 456
           T  Q        GGP        P P AA+          P  PGG  G    GG  P  
Sbjct: 177 TPPQA-------GGP--------PPPPAAVPGPGPGPKQGP-GPGGPKGGKMPGGPKPGG 220

Query: 457 SSTAQPPTQHRLVARNGEAE 476
                 P  H      G  E
Sbjct: 221 GPGLSTPGGHPKPPHRGGGE 240


>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
           sapiens]
          Length = 731

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 26/141 (18%)

Query: 413 SAETPGVPSPIAALKN--VAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVA 470
           S   P V    AAL +  VA+A G      GG GGPVR    +PA S +        L  
Sbjct: 34  SPSPPSVAVSAAALVSGGVAQAAGS-----GGLGGPVRPVLVAPAVSGSGGGAVSTGLSR 88

Query: 471 RNGEAEVSPTAGAEAVSGGGSGTGATPGAPLC---------------CTLCRERLEDTHF 515
            +  A  S   G  + S G         APLC               C +C + +E+ + 
Sbjct: 89  HSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYM 148

Query: 516 VQCPSVPGHKFCFPCSREFIK 536
            +C    GH FC+ C  + ++
Sbjct: 149 TKC----GHSFCYKCIHQSLE 165


>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
           sapiens]
          Length = 707

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 26/141 (18%)

Query: 413 SAETPGVPSPIAALKN--VAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVA 470
           S   P V    AAL +  VA+A G      GG GGPVR    +PA S +        L  
Sbjct: 34  SPSPPSVAVSAAALVSGGVAQAAGS-----GGLGGPVRPVLVAPAVSGSGGGAVSTGLSR 88

Query: 471 RNGEAEVSPTAGAEAVSGGGSGTGATPGAPLC---------------CTLCRERLEDTHF 515
            +  A  S   G  + S G         APLC               C +C + +E+ + 
Sbjct: 89  HSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYM 148

Query: 516 VQCPSVPGHKFCFPCSREFIK 536
            +C    GH FC+ C  + ++
Sbjct: 149 TKC----GHSFCYKCIHQSLE 165


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 26/216 (12%)

Query: 348 EALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTT---EEQQQRH 404
           +A P++ P P P +    PP   SR +        A P P      K      EE++ + 
Sbjct: 376 QAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKE 435

Query: 405 WVAPGGPYSAETPGVPSPIAALKNVAEALGHSP-KDPGGGGGPV-RAGGASPAA-----S 457
             AP  P  A +P +  P +  K++    G +P   P     P  RA  ASP A      
Sbjct: 436 EEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRL 495

Query: 458 STAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQ 517
           S ++PP+          A  SP    E++S        T GA L       +      V 
Sbjct: 496 SHSEPPS----------ATPSPALSVESLS--SESASQTAGAELLEPPAVPKSSSEPAVH 543

Query: 518 CPSVPGHKFCFPCSREFIKAQGPAGEVYCPSGDKCP 553
            P  PG+    P S     +   +GE+  P  ++ P
Sbjct: 544 APGTPGN----PVSLSTNSSLASSGELVEPRVEQMP 575


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
          Length = 1258

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 38/123 (30%), Positives = 50/123 (40%), Gaps = 14/123 (11%)

Query: 346  PAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRR-KASPEPEGEAAGKMTTEEQQQRH 404
            P   L ++  +P P      PPRA  R    TPR + + +PEPEG AA           +
Sbjct: 927  PLSRLFEEPEKPPPTGRPPAPPRAAPREEPLTPRLKPEGAPEPEGVAAPPPKNSFNNPAY 986

Query: 405  WVAPGGPYSAETPGVPSPI-----AALKN------VAEALGH--SPKDPGGGGGPVRAGG 451
            +V  G P+    P  PSP      +A KN       A  LGH   P+   G      +GG
Sbjct: 987  YVLEGVPHQLLPPEPPSPARAPVPSATKNKVAITVPAPQLGHHRHPRVGEGSSSDEESGG 1046

Query: 452  ASP 454
              P
Sbjct: 1047 TLP 1049


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 20/157 (12%)

Query: 320 RRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQY----PEPAPAALCGPPPRAPSRNLA 375
           RR  +G+W++       G  S   P P     +++     EP P      PPR       
Sbjct: 120 RRGKTGQWKE-------GRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRH-----G 167

Query: 376 PTPRR-RKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALG 434
           P P+  R+ S  P G  +G++   + +Q+ W      + A    V S + + K  A A  
Sbjct: 168 PHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAK-PARAPR 226

Query: 435 HSP--KDPGGGGGPVRAGGASPAASSTAQPPTQHRLV 469
            +P  ++    G   R G   PAA  +AQ P   RL+
Sbjct: 227 PAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLL 263



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 65/233 (27%), Positives = 85/233 (36%), Gaps = 49/233 (21%)

Query: 307 ALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSF-----REPAPAEA-LPQQYPEPAPA 360
           A  S G    E     GS +   L  LL     S      R P P +  L    P    A
Sbjct: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAA 295

Query: 361 ALCGPPPRAPSRNLAPTPRR--RKASPEPEGE----------------AAGKMTTEEQQ- 401
            L G   RAPS  L+P PRR  R+A   P G                 A  +   EE++ 
Sbjct: 296 PLAGS--RAPS--LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRV 351

Query: 402 --QRHWVAPGGPYSAETPGVPSPIAALKNVAE------ALGHSPKDPGGGGGPVRAGGAS 453
             +R   A G P     P  P      +   +        G SP++   G G VR GG +
Sbjct: 352 RGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEG-VR-GGVT 409

Query: 454 PAA--SSTAQPPTQ--------HRLVARNGEAEVSPTAGAEAVSGGGSGTGAT 496
           P A  SST   P+         +R +   G    +P+A AE V GG + +  T
Sbjct: 410 PRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPT 462


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 20/157 (12%)

Query: 320 RRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQY----PEPAPAALCGPPPRAPSRNLA 375
           RR  +G+W++       G  S   P P     +++     EP P      PPR       
Sbjct: 120 RRGKTGQWKE-------GRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRH-----G 167

Query: 376 PTPRR-RKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALG 434
           P P+  R+ S  P G  +G++   + +Q+ W      + A    V S + + K  A A  
Sbjct: 168 PHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAK-PARAPR 226

Query: 435 HSP--KDPGGGGGPVRAGGASPAASSTAQPPTQHRLV 469
            +P  ++    G   R G   PAA  +AQ P   RL+
Sbjct: 227 PAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLL 263



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 65/233 (27%), Positives = 85/233 (36%), Gaps = 49/233 (21%)

Query: 307 ALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSF-----REPAPAEA-LPQQYPEPAPA 360
           A  S G    E     GS +   L  LL     S      R P P +  L    P    A
Sbjct: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAA 295

Query: 361 ALCGPPPRAPSRNLAPTPRR--RKASPEPEGE----------------AAGKMTTEEQQ- 401
            L G   RAPS  L+P PRR  R+A   P G                 A  +   EE++ 
Sbjct: 296 PLAGS--RAPS--LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRV 351

Query: 402 --QRHWVAPGGPYSAETPGVPSPIAALKNVAE------ALGHSPKDPGGGGGPVRAGGAS 453
             +R   A G P     P  P      +   +        G SP++   G G VR GG +
Sbjct: 352 RGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEG-VR-GGVT 409

Query: 454 PAA--SSTAQPPTQ--------HRLVARNGEAEVSPTAGAEAVSGGGSGTGAT 496
           P A  SST   P+         +R +   G    +P+A AE V GG + +  T
Sbjct: 410 PRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPT 462


>gi|33589824 cell growth regulator with EF-hand domain 1 [Homo
           sapiens]
          Length = 301

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 11/149 (7%)

Query: 332 ELLTDGVRSFREPAPAEALPQQYPEPA-PAALCGPPPRAPSRN--LAPTPRRRKA--SPE 386
           +L  DG+ +  E      +  ++ EP  P A     P+A  R   LA +P R++   +P 
Sbjct: 127 DLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPG 186

Query: 387 PEGEAAGKMTTEEQQQRHWVAPGGPYSAETPG-VPSPIAALKNVAEALGHSPKDPGGGGG 445
           P  EA G++    +       PGG   AE  G VP P    +  AEA G +P   G  GG
Sbjct: 187 PREEAKGQVEARRESLDPVQEPGG--QAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGG 244

Query: 446 PVRAGGASPAASSTAQPPTQHRLVARNGE 474
              A G +P     A    + R    NGE
Sbjct: 245 QAEAEGDAPGPRGEAGGQAEAR---ENGE 270


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/148 (30%), Positives = 52/148 (35%), Gaps = 17/148 (11%)

Query: 359 PAALCGPPPRAPSRNLAP--TPRRRKASPEPEGEAAGK---MTTEEQQQRHWVAPGGPYS 413
           PA    PPP  P     P  TPR+ +AS EP             E    R + AP     
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP----- 209

Query: 414 AETPGVPSPIAALK--NVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVAR 471
              PG P P   L        L   P  P GGG     GG  P       PPT    V+ 
Sbjct: 210 ---PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGG--PNGGKQHPPPTTPISVSS 264

Query: 472 NGEAEVSPTAGAEAVSGGGSGTGATPGA 499
           +G +   PT       GGG+   A P A
Sbjct: 265 SGASGAPPTKPPTTPVGGGNLPSAPPPA 292


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/148 (30%), Positives = 52/148 (35%), Gaps = 17/148 (11%)

Query: 359 PAALCGPPPRAPSRNLAP--TPRRRKASPEPEGEAAGK---MTTEEQQQRHWVAPGGPYS 413
           PA    PPP  P     P  TPR+ +AS EP             E    R + AP     
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP----- 209

Query: 414 AETPGVPSPIAALK--NVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVAR 471
              PG P P   L        L   P  P GGG     GG  P       PPT    V+ 
Sbjct: 210 ---PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGG--PNGGKQHPPPTTPISVSS 264

Query: 472 NGEAEVSPTAGAEAVSGGGSGTGATPGA 499
           +G +   PT       GGG+   A P A
Sbjct: 265 SGASGAPPTKPPTTPVGGGNLPSAPPPA 292


>gi|122937424 one cut homeobox 3 [Homo sapiens]
          Length = 494

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 27/152 (17%)

Query: 351 PQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPG- 409
           P  +P PA A    PPP        P P+R  AS       +G  T    ++    + G 
Sbjct: 141 PHAHPHPAAAP---PPP--------PPPQRLAAS------VSGSFTLMRDERAALASVGH 183

Query: 410 --GPYSAETPGVPSPIAALKN-VAEALGHSPKDPGGGGGPVRAGGASP---AASSTAQPP 463
             GPY  E P + SP++ L N +  AL  +P+ P     P  A    P   A      P 
Sbjct: 184 LYGPYGKELPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPA 243

Query: 464 TQHRLVARNGEAEVSPTAGAEAVSGGGSGTGA 495
                 A  G AE    A A  + GGG GTG+
Sbjct: 244 AFEPHAALLGRAE---DALARGLPGGGGGTGS 272



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 52/189 (27%), Positives = 74/189 (39%), Gaps = 19/189 (10%)

Query: 301 LREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA 360
           +R+   ALAS G  Y  Y +     E   +G  L+    +          P   P P P 
Sbjct: 171 MRDERAALASVGHLYGPYGK-----ELPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPL 225

Query: 361 ALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVP 420
           A  GPP       L P      A+ EP     G+   E+   R     GG   +   G  
Sbjct: 226 AAYGPPGHLAGDKLLPP-----AAFEPHAALLGR--AEDALARGLPGGGGGTGSGGAGSG 278

Query: 421 SP---IAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEV 477
           S    +A L  +A A  H P   GGGGGP  +GG   A ++  +  T+   VA+   AE+
Sbjct: 279 SAAGLLAPLGGLAAAGAHGPH--GGGGGPGGSGGGPSAGAAAEEINTKE--VAQRITAEL 334

Query: 478 SPTAGAEAV 486
              +  +A+
Sbjct: 335 KRYSIPQAI 343



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 20/105 (19%)

Query: 393 GKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGA 452
           G   +   Q R  VAPG       PG+ + +A+L            D GGGGG   AGGA
Sbjct: 26  GHARSAAAQHRGLVAPG------RPGLVAGMASLL-----------DGGGGGGGGGAGGA 68

Query: 453 SPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATP 497
             A S+      +  L    G    +     EA   GG+ T  TP
Sbjct: 69  GGAGSAGGGADFRGELA---GPLHPAMGMACEAPGLGGTYTTLTP 110


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 43/169 (25%), Positives = 59/169 (34%), Gaps = 23/169 (13%)

Query: 342  REPAPAEALPQQYP------EPAPAALCGPPPRAPSRNLAPTPRRRKASPEPE-GEAAGK 394
            R PA  +A P + P      EP P  L   PP  P    A  P +   SP+P   +   K
Sbjct: 1179 RRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPK 1238

Query: 395  M---TTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGG 451
            +    T   ++     PG P      G P P++            P  P     PV+A  
Sbjct: 1239 LQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSP----------KPPPPPTAPKPVKAVA 1288

Query: 452  ASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPGAP 500
              P+ S+   P       AR   A ++   G     G       +PGAP
Sbjct: 1289 GLPSGSAGPSPAPS---PARQPPAALAKPPGTPPSLGASPAKPPSPGAP 1334



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 10/96 (10%)

Query: 66   SPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGRLPLPS 125
            SPG PAL  PA    AAAAA      PP     P G   G S + + +   +S  L    
Sbjct: 1330 SPGAPALHVPAKPPRAAAAAAAAAAAPP---APPEGASPGDSARQKLEE--TSACLAAAL 1384

Query: 126  PALEYTLGSRLANGLGREEAVAEGARRALL---GSM 158
             A+E  +  R  +  G  ++ AE +  ++L   GSM
Sbjct: 1385 QAVEEKI--RQEDAQGPRDSAAEKSTGSILDDIGSM 1418



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 11/116 (9%)

Query: 364 GPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPI 423
           GP    PS +L PTPR         G  A  M++ ++     +   GP     PG  SP+
Sbjct: 672 GPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQE-----LLGDGP-----PGPSSPM 721

Query: 424 AALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSP 479
           +  +      G +P  P     P R G +   A S    P + R V   G +  +P
Sbjct: 722 SRSQEYLLDEGPAPGTPPREARPGRHGHSIKRA-SVPPVPGKPRQVLPPGTSHFTP 776



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 43/174 (24%), Positives = 61/174 (35%), Gaps = 45/174 (25%)

Query: 54   QLKRSHVLPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYD 113
            ++KR+H  P   SP PP                    PPP A        G  SG     
Sbjct: 1259 EVKRAHGTPPPVSPKPP--------------------PPPTAPKPVKAVAGLPSG----- 1293

Query: 114  RATSSGRLPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGL----MPPGLLAA 169
               S+G  P PSPA +    + LA   G   ++     +      P L     PP   AA
Sbjct: 1294 ---SAGPSPAPSPARQPP--AALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAA 1348

Query: 170  AVSGLGSRGLTLAPGLSPARPLFGS--DFEKEKQQRNADCLAELNEAMRGRAEE 221
            A +         A    PA P   S  D  ++K +  + CLA   +A+  +  +
Sbjct: 1349 AAA---------AAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQ 1393


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 71/266 (26%), Positives = 85/266 (31%), Gaps = 57/266 (21%)

Query: 261 ATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDALREPGKALASSGFKYLEYER 320
           A   PP Y F       Y      V A   AV  Q  H   + PG A   SG        
Sbjct: 141 AALPPPAYGFG----QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSG-------- 187

Query: 321 RHGSGEWRQLGELLTDGVRSFREPAPAEALPQQ--YPEPAPA-ALCGPPPRAPSRNLAPT 377
             G G     G         F         P +  YP PAPA AL  P    P    A  
Sbjct: 188 -GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA 246

Query: 378 PRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAA------LKNVAE 431
              +   P     +A   ++   QQR     GG  SA   G P P A       L + + 
Sbjct: 247 AGSK--PPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSS 304

Query: 432 ALGH----------SPKDPGGGGGP----------VRAGGASPAASSTAQPPTQHRLVAR 471
           A G+           P+D G G GP            A  A+ AAS  AQ  + H     
Sbjct: 305 ARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH----- 359

Query: 472 NGEAEVSPTAGAEAVSGGGSGTGATP 497
              A +SP +      GGG     TP
Sbjct: 360 ---APMSPGSS----GGGGQPLARTP 378



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 46/174 (26%), Positives = 63/174 (36%), Gaps = 32/174 (18%)

Query: 357 PAPAALCGPPPRAPSRNLAPTPRRRK---------------------ASPEPEGEAAGK- 394
           PA A+  G PP  P   L    ++++                     A  E EG A G  
Sbjct: 7   PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66

Query: 395 --MTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNV------AEALGHSPKDP--GGGG 444
             +  E Q        GG   A + G P     LKN         AL ++  +P  GGGG
Sbjct: 67  QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG 126

Query: 445 GPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPG 498
           G     GA P +++ A PP  +      G +  +  A A AV     G   +PG
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 34/137 (24%), Positives = 49/137 (35%), Gaps = 17/137 (12%)

Query: 370 PSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNV 429
           P+R+  P P    A   P G   G               G   +A +   PS  A+  + 
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGS--------------GAAAAAGSKPPPSSSASASSS 262

Query: 430 AEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGG 489
           + +         GGGGP  AGG +P  ++T   PT ++L+     A           SGG
Sbjct: 263 SSSFAQQRFGAMGGGGPSAAGGGTPQPTAT---PTLNQLLTSPSSARGYQGYPGGDYSGG 319

Query: 490 GSGTGATPGAPLCCTLC 506
               GA  G     + C
Sbjct: 320 PQDGGAGKGPADMASQC 336


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 71/266 (26%), Positives = 85/266 (31%), Gaps = 57/266 (21%)

Query: 261 ATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDALREPGKALASSGFKYLEYER 320
           A   PP Y F       Y      V A   AV  Q  H   + PG A   SG        
Sbjct: 141 AALPPPAYGFG----QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSG-------- 187

Query: 321 RHGSGEWRQLGELLTDGVRSFREPAPAEALPQQ--YPEPAPA-ALCGPPPRAPSRNLAPT 377
             G G     G         F         P +  YP PAPA AL  P    P    A  
Sbjct: 188 -GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA 246

Query: 378 PRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAA------LKNVAE 431
              +   P     +A   ++   QQR     GG  SA   G P P A       L + + 
Sbjct: 247 AGSK--PPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSS 304

Query: 432 ALGH----------SPKDPGGGGGP----------VRAGGASPAASSTAQPPTQHRLVAR 471
           A G+           P+D G G GP            A  A+ AAS  AQ  + H     
Sbjct: 305 ARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH----- 359

Query: 472 NGEAEVSPTAGAEAVSGGGSGTGATP 497
              A +SP +      GGG     TP
Sbjct: 360 ---APMSPGSS----GGGGQPLARTP 378



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 46/174 (26%), Positives = 63/174 (36%), Gaps = 32/174 (18%)

Query: 357 PAPAALCGPPPRAPSRNLAPTPRRRK---------------------ASPEPEGEAAGK- 394
           PA A+  G PP  P   L    ++++                     A  E EG A G  
Sbjct: 7   PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66

Query: 395 --MTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNV------AEALGHSPKDP--GGGG 444
             +  E Q        GG   A + G P     LKN         AL ++  +P  GGGG
Sbjct: 67  QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG 126

Query: 445 GPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPG 498
           G     GA P +++ A PP  +      G +  +  A A AV     G   +PG
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 34/137 (24%), Positives = 49/137 (35%), Gaps = 17/137 (12%)

Query: 370 PSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNV 429
           P+R+  P P    A   P G   G               G   +A +   PS  A+  + 
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGS--------------GAAAAAGSKPPPSSSASASSS 262

Query: 430 AEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPTAGAEAVSGG 489
           + +         GGGGP  AGG +P  ++T   PT ++L+     A           SGG
Sbjct: 263 SSSFAQQRFGAMGGGGPSAAGGGTPQPTAT---PTLNQLLTSPSSARGYQGYPGGDYSGG 319

Query: 490 GSGTGATPGAPLCCTLC 506
               GA  G     + C
Sbjct: 320 PQDGGAGKGPADMASQC 336


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/146 (28%), Positives = 52/146 (35%), Gaps = 18/146 (12%)

Query: 330 LGELLTDGVRSFREPAPAEALPQQYPEPAPAALC-GPPPRAPSRNLAPTPRRRKASPEPE 388
           +G L     R  R P P          PAPAA   GPPP A       +PR  + SP   
Sbjct: 747 VGPLALGSPRLVRRPPPG---------PAPAAASPGPPPPASPPGAPASPRAPRTSPY-G 796

Query: 389 GEAAGKMTTEEQQQRHWVAPGGPYSAETP----GVPSPIAALKNVAEA---LGHSPKDPG 441
           G  A  +       R       P SA  P    G P P A+ +  + +   LG +P    
Sbjct: 797 GLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARA 856

Query: 442 GGGGPVRAGGASPAASSTAQPPTQHR 467
               P R   ASP A+    P    R
Sbjct: 857 AAPSPDRRDSASPGAAGGLDPQDSAR 882



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 39/141 (27%), Positives = 45/141 (31%), Gaps = 13/141 (9%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPT--PRRRKASPEPEGEAAGKMTTEEQQ 401
           P P  A PQQ P P P     PP   P    AP   P R +A P    +  G       +
Sbjct: 24  PPPPPAPPQQQPPPPP-----PPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRLRSR 78

Query: 402 QRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQ 461
                 PG      TPG  S      N     G     P G  GP R    S +    A 
Sbjct: 79  DSSCGRPG------TPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAAS 132

Query: 462 PPTQHRLVARNGEAEVSPTAG 482
            P      A    +E +  AG
Sbjct: 133 GPAPGPGPAEEAGSEEAGPAG 153


>gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 480

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 58/191 (30%), Positives = 71/191 (37%), Gaps = 37/191 (19%)

Query: 344 PAPAE-ALPQQYPEP-APAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQ 401
           P P E A P   P P AP A    P RA   +  P  R R A P P     G ++   + 
Sbjct: 199 PLPQETAAPAPQPGPTAPPARVREPGRAEGASREPRLRSRAARPPP-APGPGALSRASRS 257

Query: 402 QRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQ 461
           +    A G P     PG      A          +P+ PGGGGG       +P A   A 
Sbjct: 258 R----AAGRP----GPGFHGGEKAA---------APRAPGGGGG------RNPGALGRAA 294

Query: 462 PPTQHRLVA--RNGEAEVSPTAGAEAVSGGGSGTGATPGAPLCCTLCRERL--------E 511
           PP++ R  A   +G A V    G +    G S   AT G    C  CR R         E
Sbjct: 295 PPSRARQDAWGLSGCATVGLRRG-DCDRAGSSQPPATSGNGERCRFCRRRRRRGGGGEGE 353

Query: 512 DTHFVQCPSVP 522
            TH    P+ P
Sbjct: 354 GTHATHGPASP 364



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 4/98 (4%)

Query: 63  EGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGRLP 122
           EG   G P  + P  ++ AA A Q    P P A P      G   G  R  R  S    P
Sbjct: 187 EGSFGGRPKSQPPLPQETAAPAPQ----PGPTAPPARVREPGRAEGASREPRLRSRAARP 242

Query: 123 LPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPG 160
            P+P       +  +   GR      G  +A     PG
Sbjct: 243 PPAPGPGALSRASRSRAAGRPGPGFHGGEKAAAPRAPG 280


>gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 381

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 25/54 (46%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 339 RSFREPAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAA 392
           RS  EP PAE  P+  P P PAA   PP  APS   A +P  R+  P P   AA
Sbjct: 302 RSRGEPRPAE--PRAPPRPPPAARRPPPATAPSPRRAGSPPTREEEPRPRRSAA 353



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 344 PAPAEALPQQYPEPA-PAALCGPPP--RAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQ 400
           P PAE    + P PA P A   PPP  R P    AP+PRR  + P  E E   + +    
Sbjct: 297 PQPAERSRGE-PRPAEPRAPPRPPPAARRPPPATAPSPRRAGSPPTREEEPRPRRSAARP 355

Query: 401 Q 401
           Q
Sbjct: 356 Q 356


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 71/256 (27%), Positives = 94/256 (36%), Gaps = 50/256 (19%)

Query: 296  MFHDALREPGKALASSGFKYLEYER-RHGSGEWRQLGELL--TDGVRSF--REPAPAEAL 350
            +F+  L   G +L    +++L Y R RH  G   ++  LL  + G+ S    E AP  A 
Sbjct: 848  VFYMLLVAMGLSLLVFAWEHLVYWRLRHCLGPTHRMDFLLAFSRGMYSCCSAEAAPPPAK 907

Query: 351  PQQYPE-------PAPAALCGPPPRAPSRNLAPTPRRRK---ASP--------------- 385
            P   P+       PAP    GP P  P R  A   R R+   A P               
Sbjct: 908  PPPPPQPLPSPAYPAPRPAPGPAPFVP-RERASVDRWRRTKGAGPPGGAGLADGFHRYYG 966

Query: 386  --EPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGG 443
              EP+G   G        +     P  P +A+ P  P P       A      P +P  G
Sbjct: 967  PIEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPP----SYFAIVRDKEPAEPPAG 1022

Query: 444  GGP-VRAGGASPAASSTAQPPTQHRLVARN-----------GEAEVSPTAGAEAVSGGGS 491
              P   +  A PAA++TA  P   RL   +            + E  P  G  A   GG+
Sbjct: 1023 AFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRSDPESQPLLGPGAGGAGGT 1082

Query: 492  GTGATPGAPLCCTLCR 507
            G GA  GAP     CR
Sbjct: 1083 G-GAGGGAPAAPPPCR 1097



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 50/195 (25%), Positives = 67/195 (34%), Gaps = 52/195 (26%)

Query: 331  GELLTDGVRSFREPAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGE 390
            G  L DG   +  P   + L     E   A     P  A  R L+P   +    P P   
Sbjct: 954  GAGLADGFHRYYGPIEPQGLGLGLGEARAA-----PRGAAGRPLSPPAAQPPQKPPPSYF 1008

Query: 391  AAGKMTTEEQQQRHWVAPGGPYSAETPGVPSPIAALKNVAEALG----------HSPKDP 440
            A   +  +++       P  P +   PG PSP A     A A+G           SP  P
Sbjct: 1009 A---IVRDKE-------PAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAP 1058

Query: 441  ------------------GGGGGPVRAGGASPAASS---TAQPPTQHRLVARNGEAEVSP 479
                              GG GG   AGG +PAA      A PP  +       + E SP
Sbjct: 1059 ARWPRSDPESQPLLGPGAGGAGGTGGAGGGAPAAPPPCRAAPPPCPYL------DLEPSP 1112

Query: 480  TAGAEAVSGGGSGTG 494
            +   ++ S GG+  G
Sbjct: 1113 SDSEDSESLGGASLG 1127


>gi|22779860 forkhead box L1 [Homo sapiens]
          Length = 345

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 26/163 (15%)

Query: 355 PEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSA 414
           P+P P A     PRA +       R  +A PE    A G      + Q    AP GP   
Sbjct: 145 PKPGPGAPEAKRPRAETHQ-----RSAEAQPEAGSGAGGSGPAISRLQ---AAPAGPSPL 196

Query: 415 -ETPGVPSPI--------------AALKNVAEALGHSPKDPGGGGGPVR-AGGASPAASS 458
            + P  P+P+              AA    A A+G + +   G G P+R A  +SP +S 
Sbjct: 197 LDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSD 256

Query: 459 TAQPPTQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPGAPL 501
            ++  +   ++A  G+    P +G E + G   G G   GA L
Sbjct: 257 KSKSFSIDSILA--GKQGQKPPSGDELLGGAKPGPGGRLGASL 297


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 43/159 (27%), Positives = 54/159 (33%), Gaps = 10/159 (6%)

Query: 341 FREPAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQ 400
           F +P P   LP   P P P    GPPP  P     P P      P P G     +T    
Sbjct: 284 FGQP-PLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340

Query: 401 QQRHWVAPGGPYSA---ETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAA- 456
                  PG P  A        P P  +    +++ G  P DP G   P   G   P   
Sbjct: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGR 400

Query: 457 -SSTAQPPTQHRLVAR--NGEAEVSPTAGAEAVSGGGSG 492
              TA+ P          N    +S +A + AVS   +G
Sbjct: 401 EMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAG 439


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 13/122 (10%)

Query: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403
           P PA+  PQQ   P PA    PPP+ P    A  P ++  S +P  +  G      QQ  
Sbjct: 474 PGPAKPPPQQ---PGPAK---PPPQQPGS--AKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525

Query: 404 HWVAPGGPYSAETPGVPSPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPP 463
               P     +  P    P  A  +  ++    P    G G P++    SP+A    QPP
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQST--KPVSQTGSGKPLQPPTVSPSAK---QPP 580

Query: 464 TQ 465
           +Q
Sbjct: 581 SQ 582



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 36/160 (22%), Positives = 56/160 (35%), Gaps = 22/160 (13%)

Query: 331 GELLTDGVRSFREPAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGE 390
           G+   D V+   EP  A+      P+  P     P P  P      T    + SP+P+ +
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901

Query: 391 A------AGKMTTEEQQQRHWVAPGGPYSAETPGV----PSPIAALKNVAEALGH-SPKD 439
           +       G +T   + Q     P  P    T  +     S  +   N+    G   P  
Sbjct: 902 SRRFSLNLGSITDAPKSQ-----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956

Query: 440 PGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSP 479
             G G P++       A + +QPPT        G+A  +P
Sbjct: 957 QSGPGAPMK------QAPAPSQPPTSQGPPKSTGQAPPAP 990



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 29/122 (23%), Positives = 44/122 (36%), Gaps = 25/122 (20%)

Query: 342 REPAPAEALPQQ--------------YPEPAPAALCGPPPRAPSRNLAPTPRRRKASP-- 385
           ++P PA+  PQQ               P P       P P+ P     P+ +   A P  
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541

Query: 386 ------EPEGEAAGKMTTEEQQQRHWVAPGGPYSAETP---GVPSPIAALKNVAEALGHS 436
                 +P  + + K  ++    +    P    SA+ P   G+P  I  L N  E L H 
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601

Query: 437 PK 438
           P+
Sbjct: 602 PE 603



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 4/59 (6%)

Query: 344  PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQ 402
            PAPA+++P +    APAA        P    APT +R +   +P      K  T E Q+
Sbjct: 988  PAPAKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,231,580
Number of Sequences: 37866
Number of extensions: 1979457
Number of successful extensions: 18539
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 974
Number of HSP's that attempted gapping in prelim test: 13697
Number of HSP's gapped (non-prelim): 5155
length of query: 584
length of database: 18,247,518
effective HSP length: 108
effective length of query: 476
effective length of database: 14,157,990
effective search space: 6739203240
effective search space used: 6739203240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.