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Search of human proteins with 242117948
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|242117948 SH3 domain-containing protein C1orf113 isoform 2
[Homo sapiens]
(645 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 1305 0.0
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 1305 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 110 3e-24
gi|110349719 titin isoform N2-A [Homo sapiens] 99 9e-21
gi|11321634 CD2-associated protein [Homo sapiens] 94 3e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 84 5e-16
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 84 5e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 84 5e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 84 5e-16
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 84 5e-16
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 83 9e-16
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 83 9e-16
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 81 3e-15
gi|39930351 dynamin binding protein [Homo sapiens] 76 8e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni... 75 2e-13
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 74 5e-13
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 74 5e-13
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 74 5e-13
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 74 5e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 72 1e-12
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 72 2e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 70 6e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 68 3e-11
gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Ho... 66 9e-11
gi|155723000 mixed lineage kinase 4 [Homo sapiens] 66 1e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 1e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 65 3e-10
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 64 4e-10
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 63 1e-09
gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s... 63 1e-09
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 1305 bits (3376), Expect = 0.0
Identities = 645/645 (100%), Positives = 645/645 (100%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD 60
MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD
Sbjct: 112 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD 171
Query: 61 SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV 120
SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV
Sbjct: 172 SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV 231
Query: 121 FPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180
FPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR
Sbjct: 232 FPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 291
Query: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240
TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK
Sbjct: 292 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 351
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 300
RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD
Sbjct: 352 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 411
Query: 301 KVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPK 360
KVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPK
Sbjct: 412 KVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPK 471
Query: 361 MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH 420
MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH
Sbjct: 472 MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH 531
Query: 421 TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE 480
TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE
Sbjct: 532 TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE 591
Query: 481 APSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIER 540
APSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIER
Sbjct: 592 APSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIER 651
Query: 541 AFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQL 600
AFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQL
Sbjct: 652 AFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQL 711
Query: 601 ERKLTDIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY 645
ERKLTDIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY
Sbjct: 712 ERKLTDIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY 756
Score = 70.1 bits (170), Expect = 6e-12
Identities = 135/564 (23%), Positives = 198/564 (35%), Gaps = 105/564 (18%)
Query: 77 VLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKK-- 134
VL Y+ + DEL+L GDVV+ + + +GW GE GR G+FP+ V P +
Sbjct: 5 VLAGYRAQKEDELSLAPGDVVRQV-RWVPARGWLRGEFGGRYGLFPERLVQEIPETLRGS 63
Query: 135 --LVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSR 192
+ R P K P+ P + P +A + + + ++
Sbjct: 64 GEARRPRCARRRGHPAKHPR--------PQRWCKVNFSYSPEQADELKLQAGEIVEMIK- 114
Query: 193 DSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPE 252
+ + G+K + V E S P PS+ MP + P+
Sbjct: 115 --------EIEDGWWLGKKNGQLGAFPSNFV---ELLDSGP---PSLGNPDMPSVSPGPQ 160
Query: 253 RPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPE 312
RPP + V PE L D P + D V K T E
Sbjct: 161 RPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQ--PEAPDELALRRGDVVKVLSK--TTE 216
Query: 313 DK-----------ASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAP---PMDKVPN 358
DK P+N ++P + K P +V S E +P E P +P
Sbjct: 217 DKGWWEGECQGRRGVFPDNFVLPPPPI---KKLVPRKVVSRESAPIKEPKKLMPKTSLPT 273
Query: 359 PKMAPLGDEAPTLEKV-LTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDP---- 413
K P+ K TP +++++RD F S + + + P
Sbjct: 274 VKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRS 333
Query: 414 -SSQEEAH-------------------TPEAP--PPQPPSSERCLGEMKC-----TLVRG 446
SSQEE H TPE P P PSS++ K TL G
Sbjct: 334 VSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLG 393
Query: 447 DSSPRQAELKSG----PASRPALEKPHPHEEATTLPE-----------EAPSNDERT-PE 490
D + SG P P EK E+ ++PE + PS ER
Sbjct: 394 DKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSV 453
Query: 491 EEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPP---KEEVAPKEEVP----PIERAFA 543
EE+P E P+ + PK E TL++ L P +EEV+ ++++ E A
Sbjct: 454 EESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQ 513
Query: 544 Q-KTRPIKPPPDSQETLALPSLVP 566
+ K K P SQE P P
Sbjct: 514 KVKYFVAKEDPSSQEEAHTPEAPP 537
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 1305 bits (3376), Expect = 0.0
Identities = 645/645 (100%), Positives = 645/645 (100%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD 60
MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD
Sbjct: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD 60
Query: 61 SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV 120
SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV
Sbjct: 61 SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV 120
Query: 121 FPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180
FPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR
Sbjct: 121 FPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180
Query: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240
TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK
Sbjct: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 300
RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD
Sbjct: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 300
Query: 301 KVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPK 360
KVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPK
Sbjct: 301 KVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPK 360
Query: 361 MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH 420
MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH
Sbjct: 361 MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH 420
Query: 421 TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE 480
TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE
Sbjct: 421 TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE 480
Query: 481 APSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIER 540
APSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIER
Sbjct: 481 APSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIER 540
Query: 541 AFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQL 600
AFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQL
Sbjct: 541 AFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQL 600
Query: 601 ERKLTDIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY 645
ERKLTDIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY
Sbjct: 601 ERKLTDIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY 645
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 110 bits (276), Expect = 3e-24
Identities = 124/494 (25%), Positives = 199/494 (40%), Gaps = 88/494 (17%)
Query: 129 PPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQK 188
PP K P K ++ A +K P+K K+ K P KAK+ P ++ K
Sbjct: 561 PPEAKS--PEKEEAKSPAEVKSPEKA--KSPAKEEAKSPAEAKSPEKAKS---PVKEEAK 613
Query: 189 LTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQ-----RSVSSQEEEHSSPVKAPSVKRTP 243
+ P + +++K+ T ++ ++ S ++EE SP KA S P
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS----P 669
Query: 244 MPDKTATPERPPAPENA----PSSKKIPAPDKVPSPEKTLT-LGDKASIPGNSTSGKIPA 298
+ + +PE+ +P A P K P ++ SPEK + + ++A P + S P
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS---PV 726
Query: 299 PDKVPTPEKMVTP-EDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVP 357
++ TPEK +P +++A PE + PE+ T+D S + + EE+ + P DK P
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS----PADKFP 782
Query: 358 NPKMAPLGDEAPTLEKVLTP-----ELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKED 412
+P+ +E + EK +P + E+E+ +++++ EE Q+VK KE
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK-SPVKEEEKPQEVK---VKEP 838
Query: 413 PSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASR------PALE 466
P EE P P + + DS +A K P + PA+E
Sbjct: 839 PKKAEEEKAPATPKTEE---------------KKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 467 KPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGV--------------- 511
KP + E TPE+EAP + ++E+ PKE
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE--VKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 512 --------ASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPD----SQETL 559
A+ E+ KEE K E PK E E P KP + S T
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD 1001
Query: 560 ALPSLVPQNYTENK 573
S P+ TE+K
Sbjct: 1002 QKDSKPPEKATEDK 1015
Score = 96.7 bits (239), Expect = 6e-20
Identities = 111/449 (24%), Positives = 200/449 (44%), Gaps = 59/449 (13%)
Query: 214 KTQTPQQRSVSSQEEEHSSPV----KAPSVKRTPMPDKTATPERPPAPENA--PSSKKIP 267
+T++P +S E+E SPV K+P+ ++P ++ +P +PE A P+ ++
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 268 APDKVPSPEKTLTLGDKASIPGNSTS---GKIPAPDKVPTPEKMVTPED-KASIPENSII 323
+P + SPEK ++A P S K PA ++ +P + +PE K+ + E +
Sbjct: 560 SPPEAKSPEK-----EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 324 PEETLT--VDKPSTPERVFSVEESPALEAPPMDKVPNPKMA--PLGDEAPTLEKVLTPEL 379
P E + ++ +P V S E++ ++P ++ +P+ A P +EA + EK +P
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKA---KSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671
Query: 380 SEEE--VSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLG 437
+E + + ++ S E+A V KE+ S E+A +P + P +
Sbjct: 672 AEAKSPEKAKSPVKAEAKSPEKAKSPV-----KEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Query: 438 EMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAP------SNDERTPEE 491
+ + SP + E KS EK E+A TL ++P + R+P +
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSP-------EKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 779
Query: 492 EAPPNEQRPLREEV---------LPKEGVASKEEVTLKEEL--PPKEEVAPKE---EVPP 537
+ P + P++EEV L ++ A ++E+ KEE+ P KEE P+E + PP
Sbjct: 780 KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 538 --IERAFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLR-RALE 594
E A T + DS++ A P+ E K E +VE+ + A +
Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899
Query: 595 LMEVQLERKLTDIWEELKSEKEQRRRLEV 623
+V K E+K + + + + EV
Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Score = 50.1 bits (118), Expect = 6e-06
Identities = 79/371 (21%), Positives = 145/371 (39%), Gaps = 58/371 (15%)
Query: 287 IPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESP 346
IP ST K+ + +K+ EK S E I+ E+T ++ E V EE
Sbjct: 429 IPSVSTHIKVKSEEKIKVVEK--------SEKETVIVEEQT---EETQVTEEVTEEEEKE 477
Query: 347 ALEAPPMDKVPNPKMAPLGDE----APTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQ 402
A E ++ + G E +P E+ +PE +EA
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPE-------------------KEAKS 518
Query: 403 KVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASR 462
VK E+ S EA +PE + P+ + + K SP +A+ ++
Sbjct: 519 PVK-----EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK 573
Query: 463 PALEKPHPHEEATTLPEEAPSNDE-RTPEE---------EAPPNEQRPLREEVLPKEGVA 512
E P + + EEA S E ++PE+ ++P + P++EE V
Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 513 SKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTEN 572
S E K + P KEE E+ E+ A+ K P ++ + P E
Sbjct: 634 SPE----KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK-AEA 688
Query: 573 KNEGVDVTSLRGEVESLRRALELMEVQL---ERKLTDIWEELKSEKEQRRRLEVQVMQGT 629
K+ + ++ E +S +A ++ + E+ + + EE K+ ++ + ++ + +
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-KSP 747
Query: 630 QKSQTPRVIHT 640
+K+++P T
Sbjct: 748 EKAKSPEKAKT 758
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 99.4 bits (246), Expect = 9e-21
Identities = 119/490 (24%), Positives = 184/490 (37%), Gaps = 70/490 (14%)
Query: 129 PPPIKKLVPRKVVSRESAPIKEPKKL-MPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
PPP P++VV + P+ PKK +P T +P V K A P K P +
Sbjct: 10521 PPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAV----PEKKVPEAIPPKPES 10576
Query: 188 KLTSRDSGPNGGF-QSGGSYHPGRKRSKT--QTPQQ-RSVSSQEEEHSSPVKAPSVKRTP 243
P + P +K T + P+ + V +++ P K P V T
Sbjct: 10577 PPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTK 10636
Query: 244 MPD--KTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASI---PGNSTSGKIPA 298
+P+ K A PE+ PE P + P P+ PE+ A + P + ++
Sbjct: 10637 VPEVPKVAVPEKK-VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTV 10695
Query: 299 PDKVPTPEKMVT------PE-DKASIPE--NSIIPEETLTVDKPSTPERVFSVEESPALE 349
P K P PEK PE +PE ++PE+ + + P PE + E
Sbjct: 10696 PPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE 10755
Query: 350 APPMDKVPNPKM-------APLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQ 402
P KV PK P + P LE+ + E S ++ + EE
Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEV---YEEPEEIAP 10812
Query: 403 KVKYFVAKEDPSSQEEAHTPEAPPPQPPSS-ERCLGEMKCTLVRGDSSPRQAELKSGPAS 461
+ + +E P E PE PPP P ++ + E K +++ +P E P
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKE----PEP 10868
Query: 462 RPALEKPHPHEEATTLPEEAPSNDERT--------PEEEAPPNEQRPLREEV-------- 505
+EKP P P D + P+++ P Q P + E+
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928
Query: 506 -------LPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTR----PIKPPPD 554
LP+ KEEV LK L + P+EE P +E +K + P PPP
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKR----PEEEEPKVEPKKLEKVKKPAVPEPPPPK 10984
Query: 555 SQETLALPSL 564
E + +P++
Sbjct: 10985 PVEEVEVPTV 10994
Score = 91.3 bits (225), Expect = 3e-18
Identities = 106/437 (24%), Positives = 170/437 (38%), Gaps = 79/437 (18%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKL-MPKTSLPTVKKLATATTG---PSKAKTSRTPS 183
PPP VP+K V E P+ PKK+ P +P V K P+ K P+
Sbjct: 9999 PPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058
Query: 184 RDSQ---KLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240
+ + KL + P TP + V + P K P K
Sbjct: 10059 KVPEVPKKLIPEEKKP--------------------TPVPKKVEAP------PPKVPK-K 10091
Query: 241 RTPMPDKTATPERPPA---PENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIP 297
R P+P A P+ E P + +P ++V E+ + ++ +P +IP
Sbjct: 10092 REPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEE---EIP 10148
Query: 298 APDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPS---------TPERVF--SVEESP 346
++ PE+ PE++ +PE ++PE V P+ T ++V EE+P
Sbjct: 10149 PEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP 10208
Query: 347 ALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKY 406
+ P + K K L E L +T E EE +S +
Sbjct: 10209 PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEE------------------ 10250
Query: 407 FVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASR---P 463
+ +E PS +E APP P ++ + E + + +P K P + P
Sbjct: 10251 -IPEEPPSIEEVEEV--APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVP 10307
Query: 464 ALEKPHPHEEATTLPEEAPSNDERTPEEEA-PPNEQRPLREEVLPKEGVASKEEVTLKEE 522
+K P + +P++ P P++EA PP + R + EE K VA ++EV +KE
Sbjct: 10308 VQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEE---KVSVAFRQEVVVKER 10364
Query: 523 LPPKEEVAPKEEVPPIE 539
L + A EE+P E
Sbjct: 10365 LELEVVEAEVEEIPEEE 10381
Score = 82.4 bits (202), Expect = 1e-15
Identities = 122/509 (23%), Positives = 185/509 (36%), Gaps = 104/509 (20%)
Query: 130 PPIKKLVPRK-VVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQK 188
PP K RK VV E I+ PK+ P K T +A T + Q+
Sbjct: 9688 PPAKVTEFRKRVVKEEKVSIEAPKRE------PQPIKEVTIMEEKERAYTLEEEAVSVQR 9741
Query: 189 LTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEE------EHSSPVKAPSVKRT 242
+ ++ Y P + + + ++R EE E P+ V
Sbjct: 9742 EEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEE 9801
Query: 243 PMPDKTATPERPPA-------PEN---APSSKKI-PAPDKVPSPEK---------TLTLG 282
P+P K P+ PPA PE P KK+ P P KVP K ++T
Sbjct: 9802 PVPTK---PKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKR 9858
Query: 283 DKASIPGNSTSGKIP-------APDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPST 335
+K + + K+P A +KVP P K V P + + PEE ++ T
Sbjct: 9859 EKEQV--TEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVT 9916
Query: 336 PERVFSVEES------------------------PALEAPPMDKVPNPKMAPLGDEAPTL 371
+ VEE P + P+ + P P EAP
Sbjct: 9917 HVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA 9976
Query: 372 EKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTP-----EAPP 426
+ P+ EE+V +E K + P +E+ P EAPP
Sbjct: 9977 KVPEVPKKPEEKVPVL-------IPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPP 10029
Query: 427 PQPPS-SERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSND 485
+ P ++ + E K + P ++++ PA P + K EE P
Sbjct: 10030 AKVPEVPKKPVPEKKVPV------PAPKKVEAPPAKVPEVPKKLIPEEKKPTP------- 10076
Query: 486 ERTPEE-EAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAP-KEEVPPIERAFA 543
P++ EAPP + RE V + +EEV +EE+ P+EEV P +EEV P E
Sbjct: 10077 --VPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVL 10134
Query: 544 QKTRPIKP-----PPDSQETLALPSLVPQ 567
+ + P PP+ +E VP+
Sbjct: 10135 PEEEEVLPEEEEIPPEEEEVPPEEEYVPE 10163
Score = 81.6 bits (200), Expect = 2e-15
Identities = 97/349 (27%), Positives = 143/349 (40%), Gaps = 81/349 (23%)
Query: 219 QQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKT 278
++ ++ +E PVK P V R P+P+ E+ P P P K+ P P KVP K
Sbjct: 9933 EEEFITEEEVVPVIPVKVPEVPRKPVPE-----EKKPVP--VPKKKEAP-PAKVPEVPKK 9984
Query: 279 LTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPER 338
+ +P + P P KVP K PE+K +P +P++ V+ P P +
Sbjct: 9985 ----PEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP----VPKK---VEAP--PAK 10031
Query: 339 VFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSE 398
V V + P P KVP P AP EAP + PE+ ++ +
Sbjct: 10032 VPEVPKKPV----PEKKVPVP--APKKVEAPPAK---VPEVPKKLI-------------- 10068
Query: 399 EALQKVKYFVAKEDPSSQEEAHTP---EAPPPQPPSSER------CLGEMKCTLVRGDSS 449
P ++ P EAPPP+ P L + + L +
Sbjct: 10069 --------------PEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIV 10114
Query: 450 PRQAELKSGPASRPALEKPHPHEEATTLPEEA---PSNDERTPEEEAPPNEQRPLREE-- 504
P + L P E+ P EE LPEE P +E PEEE P E+ + EE
Sbjct: 10115 PEEEVLPEEEEVLPEEEEVLPEEEEV-LPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV 10173
Query: 505 ---VLPKEGVAS-----KEEVTLKEELPPKEEVAPKEEVPPIERAFAQK 545
V PK V + K++VT K+ + PK+E AP +VP + + +K
Sbjct: 10174 LPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222
Score = 80.9 bits (198), Expect = 3e-15
Identities = 115/508 (22%), Positives = 184/508 (36%), Gaps = 100/508 (19%)
Query: 220 QRSVSSQEEEHSSPVKAPSV---------KRTPMPDKTATPERPP-----APENAPSSKK 265
+ V EE P K P V K+ P+P PE PP AP+ KK
Sbjct: 10479 EEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPP-AKKPEAPPPKVPEAPKEVVPEKK 10537
Query: 266 IPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPE-----KMVTPEDK---- 314
+P P K P + KA++P IP + P PE K V PE K
Sbjct: 10538 VPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAA 10597
Query: 315 ---------ASIPE--NSIIPEETLTVDKPSTPE-------------------------- 337
+PE ++PE+ + V P PE
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK 10657
Query: 338 ------RVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQ 391
VF E ALE PP + V P+ A +K + + + V+ + ++
Sbjct: 10658 PESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPEL- 10716
Query: 392 FHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPR 451
+ +V V E PEAPP + P + + K V
Sbjct: 10717 -----PPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP 10771
Query: 452 QAELKSGPASRPALEK----PHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPL-----R 502
A++ P +P LE+ P P + PE +E PEEE P E++P+
Sbjct: 10772 PAKVPEVP-KKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 503 EEVLPKEGVASKEEVTLKEELPP---KEEVAPKEEVPPIERAFAQKTRPIKPPP------ 553
E +P V + + + E+ P K E P +E P + K +P PPP
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPK 10890
Query: 554 -DSQETLALPSLVPQNYTENK---NEGVDVTSLR--GEVESLRRALELMEVQLERKLTDI 607
D +E + +P+ K E V++T L+ G + +R+ L + + + ++
Sbjct: 10891 EDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLK 10950
Query: 608 WEELKSEKEQRRRLEVQVMQGTQKSQTP 635
K +E+ ++E + ++ +K P
Sbjct: 10951 SVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978
Score = 80.9 bits (198), Expect = 3e-15
Identities = 136/578 (23%), Positives = 218/578 (37%), Gaps = 110/578 (19%)
Query: 51 PPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWW 110
PPK+ + P+ V P+ V PE P + A+ V + + E
Sbjct: 10522 PPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP-KAAVPEKKVPEAIPPKPESPPPE 10580
Query: 111 EGECQGRRGVFPDNFVLPPPPIKKLV--------PRKVVSRESAPIKEPKKL-MPKTSLP 161
E + V P+ V PP K V P++VV + P+ PKK +P T +P
Sbjct: 10581 VPEAP--KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP 10638
Query: 162 TVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQR 221
V K+A P K P + +S P F+ + + P
Sbjct: 10639 EVPKVAV----PEKKVPEAIPPKP-------ESPPPEVFEEP-------EEVALEEPPAE 10680
Query: 222 SVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTL 281
V +E E ++P + + P+P+K A PE P K+P K PEK + L
Sbjct: 10681 VV--EEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPV--KVPEVPKEVVPEKKVPL 10736
Query: 282 GDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFS 341
+P + P KVP K V PE K ++P+ +P + P P++
Sbjct: 10737 ----VVPKKPEA----PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV----PEVPKKPV- 10783
Query: 342 VEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEAL 401
+EE PA+ P + P P++ +E E++ E V+ ++ + + E
Sbjct: 10784 LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP 10843
Query: 402 QKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKC---------TLVRGDSSPRQ 452
+K+ K+ P ++ PEAPPP+ P E+ + + K + D +
Sbjct: 10844 KKI--IPEKKVPVIKK----PEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKI 10897
Query: 453 AELKSGPASRPALEKPHPHEEATTLPEEAPSNDERT----PEEEAPPNEQRPLR------ 502
+LK+ P + EKP E+ P + P +++ PE + P E+ L+
Sbjct: 10898 FQLKAIPKKKVP-EKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR 10956
Query: 503 -EEVLPKEGVASKEEV---TLKEELPPK--EEV--------------------------- 529
EE PK E+V + E PPK EEV
Sbjct: 10957 PEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL 11016
Query: 530 -APKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
AP+ + P K P++P P +A P VP
Sbjct: 11017 PAPEPKPKPEAEVKTIKPPPVEPEP---TPIAAPVTVP 11051
Score = 72.4 bits (176), Expect = 1e-12
Identities = 135/593 (22%), Positives = 210/593 (35%), Gaps = 114/593 (19%)
Query: 39 PDMPSVSPGPQR----PPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRG 94
P+ +P P++ PPK+ P V+ P+ VLF+ + +E+
Sbjct: 10069 PEEKKPTPVPKKVEAPPPKVPKKREPVPVP----VALPQEEEVLFEEEIVPEEEVLPEEE 10124
Query: 95 DVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPP-----PPIKKLVPRK---VVSRESA 146
+V+ + ++ V P+ +PP PP ++ VP + V E
Sbjct: 10125 EVLPEEEEVLPEE----------EEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVL 10174
Query: 147 PIKEPKKLMPKTSLPTVKKLATA--TTGPSK-----AKTSRTPSRDSQKLTSRDSGPNGG 199
P +PK +P +P +KK T P K AK P + +K
Sbjct: 10175 PEVKPKVPVP-APVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV- 10232
Query: 200 FQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDK-TATPERPPAPE 258
+ P + + + S +E E +P + P V + +P+ T P++ AP
Sbjct: 10233 LPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPP 10292
Query: 259 NAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIP 318
A SKKIP +KVP P + K P KVP K V PE K +P
Sbjct: 10293 -AKVSKKIPE-EKVPVPVQK----------------KEAPPAKVPEVPKKV-PEKKVLVP 10333
Query: 319 ENSIIPE---ETLTVDKPSTPERV-FSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKV 374
+ +P T+ +K S R V+E LE + P+ + E
Sbjct: 10334 KKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFE-- 10391
Query: 375 LTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSER 434
E EV ++ H E ++KV + + E P+APP P SE+
Sbjct: 10392 ---EGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448
Query: 435 CLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPE---- 490
+ K + K PA P + K EE +PEE + PE
Sbjct: 10449 IIPPKK-------PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPP 10501
Query: 491 ----------------EEAPPNEQRPLREEVLPKEGV--------------------ASK 514
EAPP + +EV+P++ V A+
Sbjct: 10502 KEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAV 10561
Query: 515 EEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQ 567
E + E +PPK E P E + +K P PP + T P VP+
Sbjct: 10562 PEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT---PVKVPE 10611
Score = 71.2 bits (173), Expect = 3e-12
Identities = 112/480 (23%), Positives = 175/480 (36%), Gaps = 84/480 (17%)
Query: 128 PPPP--IKKLVPRKV--VSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPS 183
PPPP IKK V K+ SR K +P+ S V + + T + + P+
Sbjct: 9175 PPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPA 9234
Query: 184 RDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTP 243
++K+ + + + H + S T Q+ + ++E+ H A S + P
Sbjct: 9235 VHTKKMVISEE------KMFFASHTEEEVSVTVPEVQKEIVTEEKIHV----AISKRVEP 9284
Query: 244 MPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIP-----A 298
P PE+P E AP +P P KV P + K +P +P A
Sbjct: 9285 PPKVPELPEKPAPEEVAP----VPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAA 9340
Query: 299 PDKVPTPEKMVTPEDKASIP---ENSIIPEETLTVDKPSTPERVFSV----EESPALEAP 351
P KVP K PE+K +P + P + V K E ++ EESP P
Sbjct: 9341 PPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPP---P 9397
Query: 352 PMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKE 411
+ ++P K+ P E+ + P KV K
Sbjct: 9398 AVPEIPKKKVPEERKPVPRKEEEVPPP-----------------------PKVPALPKKP 9434
Query: 412 DPSSQEEAHTP---EAPPPQPPSSERCLGEMKCTLVRGDSS---PRQAELKSGPASRPAL 465
P + P +APPP+ S++ + E K + S P++ E+ S A
Sbjct: 9435 VPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVS--AE 9492
Query: 466 EKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLRE----------EVLPKEGVASKE 515
E+ EE + +ER EEEA E + E ++ K A
Sbjct: 9493 EEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPA 9552
Query: 516 EVT--------LKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQ 567
EVT LK ++P K E P +VP + + + P P ++ P VP+
Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEK--VPPPKVPE 9610
Score = 71.2 bits (173), Expect = 3e-12
Identities = 102/457 (22%), Positives = 165/457 (36%), Gaps = 78/457 (17%)
Query: 126 VLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKT-SLPTVKKLATATTGPSKAKTSRTPSR 184
V PPP + +L P K E AP+ PKK+ P +P V K P + K P +
Sbjct: 9282 VEPPPKVPEL-PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPV----PEEKKPVPVPKK 9336
Query: 185 DSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQR-SVSSQEEEHSSPVKAPSVKRTP 243
+ P K P+++ V +++ + P K P V++
Sbjct: 9337 EPAAPPKVPEVP-----------------KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV 9379
Query: 244 MPDK-----TATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPA 298
+ ++ T E PP KK+P ++ P P K ++P
Sbjct: 9380 VTEEKITIVTQREESPPPAVPEIPKKKVP-EERKPVPRK---------------EEEVPP 9423
Query: 299 PDKVPTPEKMVTPEDKASIP---ENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDK 355
P KVP K PE+K ++P P K E+ F EE + P +
Sbjct: 9424 PPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVE 9483
Query: 356 VPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSS 415
V +++ + + SEEE + EE +V + E+P
Sbjct: 9484 VTRHEVSAEEEWS----------YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEE 9533
Query: 416 ---QEEAH----TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGP---ASRPAL 465
+E+ H EA P + + +K + P A++ P +
Sbjct: 9534 YVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKV 9593
Query: 466 EKPHPHEEATTLPEEAPSNDERTPEEEAPP---NEQRPLREEVLPKEGVASKEEVTL--- 519
P P +E P+ + PE++ PP + PL +V + ++EE L
Sbjct: 9594 PAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAV 9653
Query: 520 -KEELPPKEEV--APKEEVPPIERAFAQKTRPIKPPP 553
K+E PPK V PK VP E+ K + + PP
Sbjct: 9654 TKKEAPPKARVPEEPKRAVPE-EKVLKLKPKREEEPP 9689
Score = 62.4 bits (150), Expect = 1e-09
Identities = 124/540 (22%), Positives = 197/540 (36%), Gaps = 124/540 (22%)
Query: 126 VLPPPPIKKLVPRKVVSRESAPIKEPKKL---------MPKTSLPTVKKLATATTGPSKA 176
V PP P VP+K V E P+ PKK +PK +P +K+ +A
Sbjct: 9309 VEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPE-EKIPVPVAKKKEA 9367
Query: 177 KTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKR-SKTQTPQQRS-VSSQEEEHSSPV 234
++ P + QK + Q S P K + P++R V +EEE P
Sbjct: 9368 PPAKVP--EVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPP 9425
Query: 235 KAPSVKRTPMP-DKTATP----ERPPAPENAPSSKKIPAPDKVPSPEK-TLTLGDKASIP 288
K P++ + P+P +K A P ++ P P S K + + + EK + + + +
Sbjct: 9426 KVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVT 9485
Query: 289 GNSTSGK-----------------------------------IPAPDKVPTPEKM----- 308
+ S + + P++ EK+
Sbjct: 9486 RHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK 9545
Query: 309 --------VTPEDKASIPENSIIP---EETLTVDKPSTPERVFSVEESPALEAPPMDKVP 357
VT + I IP EE P P+++ ++ PA P +KVP
Sbjct: 9546 RVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPA-PVPKKEKVP 9604
Query: 358 NPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQE 417
PK+ P + P EK + P++ + E + H + Q+ K VA +
Sbjct: 9605 PPKV-PEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHM---QITQEEKVLVAVTKKEAPP 9660
Query: 418 EAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSP------RQAELKSGPASRPALEK-PHP 470
+A PE P P + +K R + P R+ +K S A ++ P P
Sbjct: 9661 KARVPEEPKRAVPEEK----VLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQP 9716
Query: 471 HEEAT---------TLPEEAPS--NDERTPE---------EEAPPNEQRPLREEVLPK-- 508
+E T TL EEA S +E E EE P E+ EE +
Sbjct: 9717 IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREY 9776
Query: 509 EGVASKEEVTLKEELP------PKEEVAPKEEVPP---IERAFAQKTRPI------KPPP 553
E EE + E P P+E V K + PP +++A ++ P+ KPPP
Sbjct: 9777 ERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP 9836
Score = 60.8 bits (146), Expect = 4e-09
Identities = 104/441 (23%), Positives = 175/441 (39%), Gaps = 51/441 (11%)
Query: 220 QRSVSSQEEEHSSPVKAPSVKRTPMPDKTATP--ERPPAPENAPSSKKIPAPDKVPSPEK 277
Q+ V + E P K P K P P P E+ +K+ KVP K
Sbjct: 9153 QKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQV-TKVPEVSK 9211
Query: 278 TLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPE 337
+ + P ++ P +KMV E+K ++ EE ++V P +
Sbjct: 9212 KIVPQKPSRTPVQEEVIEVKVP--AVHTKKMVISEEKMFFASHT---EEEVSVTVPEVQK 9266
Query: 338 RVFSVEE-----SPALEAPPMDKVPNPKMAPLGDE---APTLEKVLTPELSEEEVSTR-- 387
+ + E+ S +E PP KVP P +E P +KV P EV +
Sbjct: 9267 EIVTEEKIHVAISKRVEPPP--KVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPV 9324
Query: 388 -DDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTP-----EAPPPQPPSSER-CLGEMK 440
++ + +E K + P +E+ P EAPP + P ++ + E K
Sbjct: 9325 PEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEK 9384
Query: 441 CTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRP 500
T+V Q E +S P + P + K EE +P + EEE PP + P
Sbjct: 9385 ITIV------TQRE-ESPPPAVPEIPKKKVPEERKPVPRK---------EEEVPPPPKVP 9428
Query: 501 -LREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETL 559
L ++ +P+E VA V K+ PP+ EV+ K+ V +R A++ P + T
Sbjct: 9429 ALPKKPVPEEKVAVPVPVA-KKAPPPRAEVS-KKTVVEEKRFVAEEKLSFAVPQRVEVTR 9486
Query: 560 ALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQLERKLTDIWEELKSEKEQ-- 617
S + + EGV ++ R E E+ E ++ + + E + EK
Sbjct: 9487 HEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEV---MEEPEEYVVEEKLHII 9543
Query: 618 RRRLEVQVMQGTQKSQTPRVI 638
+R+E + + T++ + V+
Sbjct: 9544 SKRVEAEPAEVTERQEKKIVL 9564
Score = 59.7 bits (143), Expect = 8e-09
Identities = 135/594 (22%), Positives = 211/594 (35%), Gaps = 126/594 (21%)
Query: 120 VFPDNFVLPPPPIK-KLVPRKVVSRESAPIKEPKKLMPKT----------------SLPT 162
+ P+ V P P K K+ P KV P+ E KK+ PK +
Sbjct: 9587 IVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPE-KKVPPKVIKMEEPLPAKVTERHMQITQ 9645
Query: 163 VKKLATATT---GPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKR------- 212
+K+ A T P KA+ P R + P + RKR
Sbjct: 9646 EEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705
Query: 213 ---------------------SKTQTPQQRSVSSQEEEHSSPVKAPSVK----------- 240
+ T ++ +VS Q EE + K
Sbjct: 9706 SIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEY 9765
Query: 241 ------------RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIP 288
R ++ T P P + +P K P P K L K ++P
Sbjct: 9766 DQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAP-PAKVL----KKAVP 9820
Query: 289 GNSTSGKIPAPDKVPTPEKMVTPEDKASIPEN---SIIPEETLTVDKPST-----PERVF 340
+P P K+ P V E K E SI E V +P+ P+RV
Sbjct: 9821 EEKV--PVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVV 9878
Query: 341 SVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPE--LSEEEVSTRDDIQFHHFSSE 398
+ E+ P VP ++AP P + K L PE EEEV T + ++ E
Sbjct: 9879 AEEKVP---------VPRKEVAP-PVRVPEVPKELEPEEVAFEEEVVTHVE-EYLVEEEE 9927
Query: 399 EALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCL---GEMKCTLVRGDSSPRQAEL 455
E + + + F+ +E+ PE P P ++ + + + + P++ E
Sbjct: 9928 EYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEE 9987
Query: 456 KSGPASRPALEKPHPHEEATTLPE--EAPSNDERTPEEEAPPNEQRPLREEVLPKEGVAS 513
K P P EKP P +PE + P +E+ P E P + +PK+ V
Sbjct: 9988 KV-PVLIPKKEKPPP----AKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPE 10042
Query: 514 KEEVTLKEELP-PKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTEN 572
K K +P PK+ AP +VP + + + + KP P ++ A P VP+
Sbjct: 10043 K-----KVPVPAPKKVEAPPAKVPEVPKKLIPEEK--KPTPVPKKVEAPPPKVPK----- 10090
Query: 573 KNEGVDVTSLRGEVESLRRALELMEVQLERKLTDIWEELKSEKEQRRRLEVQVM 626
K E V V + E + L E+ E ++ EE+ E+E+ E +V+
Sbjct: 10091 KREPVPVPVALPQEEEV---LFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL 10141
Score = 47.8 bits (112), Expect = 3e-05
Identities = 52/242 (21%), Positives = 94/242 (38%), Gaps = 20/242 (8%)
Query: 149 KEPKKLMPKTSLPTVKKL-ATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYH 207
+EPKK++P+ +P +KK A P K P + + P +
Sbjct: 10841 EEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKE--KIF 10898
Query: 208 PGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKI- 266
+ K + P++ V + E +P+K P ++ + PER P P+ K +
Sbjct: 10899 QLKAIPKKKVPEKPQVPEKVE--LTPLKVPGGEKKV---RKLLPERKPEPKEEVVLKSVL 10953
Query: 267 ---PAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSII 323
P ++ K L K ++P + P P V E + + IPE + +
Sbjct: 10954 RKRPEEEEPKVEPKKLEKVKKPAVP------EPPPPKPVEEVEVPTVTKRERKIPEPTKV 11007
Query: 324 PEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEE 383
PE + P+ + E ++ PP++ P P AP+ P + K + +EE
Sbjct: 11008 PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPV--TVPVVGKKAEAKAPKEE 11065
Query: 384 VS 385
+
Sbjct: 11066 AA 11067
Score = 35.8 bits (81), Expect = 0.13
Identities = 86/412 (20%), Positives = 136/412 (33%), Gaps = 100/412 (24%)
Query: 244 MPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVP 303
MP + PE P P +P P++ P K + + KA + K+ A K
Sbjct: 8947 MPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAV---KKDAKKVVAKPKEM 9003
Query: 304 TPEKMVTPEDKASIPENSIIPEE-----------------TLTVDKPSTPERVFSVEESP 346
TP + + K P ++IP + T+T K E+ E+
Sbjct: 9004 TPREEIV---KKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQ 9060
Query: 347 AL-----------EAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHF 395
A+ E P + P P E P E+ P+ EE+ + H
Sbjct: 9061 AVHKEKRVFIESFEEPYDELEVEPYTEPF--EQPYYEE---PDEDYEEIKVEAKKEVHEE 9115
Query: 396 SSEEALQKVKYFVAKEDPSSQEE----------------------------AHTPEAPPP 427
E+ + +Y+ +E EE A PE P
Sbjct: 9116 WEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAP 9175
Query: 428 QPP------------SSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEK------PH 469
PP + R + E K + + ++ + P+ P E+ P
Sbjct: 9176 PPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKI-VPQKPSRTPVQEEVIEVKVPA 9234
Query: 470 PHEEATTLPEEAPSNDERTPEE---EAPPNEQRPLREE---VLPKEGVASKEEVTLKEEL 523
H + + EE T EE P ++ + EE V + V +V E
Sbjct: 9235 VHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEK 9294
Query: 524 PPKEEVA----PKEEVPPIERAFAQKTRPI----KPPPDSQETLALPSLVPQ 567
P EEVA PK+ PP + +P+ KP P ++ A P VP+
Sbjct: 9295 PAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPE 9346
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 94.4 bits (233), Expect = 3e-19
Identities = 104/424 (24%), Positives = 167/424 (39%), Gaps = 108/424 (25%)
Query: 3 KEIEDGWWLGKKNGQLGAFPSNFVELLD------------------SGP----PSLGNPD 40
+E+E+GWW G N +LG FPSNFV+ L+ +GP PSLGN
Sbjct: 139 EEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVS 198
Query: 41 MPSVSPGPQRPPKLSSLAYDS------------------------PPDYLQT-------- 68
+ S +P K+ + + P LQ+
Sbjct: 199 -ETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSV 257
Query: 69 ----------VSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRR 118
+ E R LF Y+ DEL + G+++ ++SK T + GWW GE G+
Sbjct: 258 EITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKE 317
Query: 119 GVFPDNFVL--------------PPPPIKKLVPR-KVVSRESAPIK-EPKKLMPKTSLPT 162
GVFPDNF + PPPP K P+ ++++ E +P++ K++L
Sbjct: 318 GVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQ 377
Query: 163 VKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQ-R 221
A P K T P++ S L +S G+ +P R P
Sbjct: 378 KPSKPAAPQVPPKKPT--PPTKASNLL-----------RSSGTVYPKRPEKPVPPPPPIA 424
Query: 222 SVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPE----NAPSSKKIPAP--DKVPSP 275
++ + SS + V + + D P RP + + +SK+ D + S
Sbjct: 425 KINGEVSSISSKFETEPVSKLKL-DSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASS 483
Query: 276 EKTLTL-GDKASIPGNSTSGKI-PAPDKVPTPEKMV---TPEDKASIPENSIIPEETLTV 330
E L L ++ +PG G+ +PEK++ ED A++ + S + ++T
Sbjct: 484 ENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANL-KPSELKKDTCYS 542
Query: 331 DKPS 334
KPS
Sbjct: 543 PKPS 546
Score = 70.5 bits (171), Expect = 5e-12
Identities = 103/454 (22%), Positives = 167/454 (36%), Gaps = 104/454 (22%)
Query: 6 EDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSL-----AYD 60
E+GW G+ NG+ G FP NFV+ + + S+ +R ++SL Y
Sbjct: 34 EEGWLEGELNGRRGMFPDNFVKEIKRETEFKDD----SLPIKRERHGNVASLVQRISTYG 89
Query: 61 SPPDYLQTVSHPEV-----------YRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGW 109
P +Q HP+ +VLF+Y P+ DEL L+ GD++ + + E GW
Sbjct: 90 LPAGGIQ--PHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEE--GW 145
Query: 110 WEGECQGRRGVFPDNFVL-----------------------PPPPIKKLVPRKVVSRESA 146
W G + G+FP NFV P PI L V S
Sbjct: 146 WSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSL--GNVSETASG 203
Query: 147 PIKEPK----------------KLMPKTSLPTV------KKLATATTGPSKAKTSRTPSR 184
+ +PK KL +TS K L + GP T +
Sbjct: 204 SVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTD 263
Query: 185 DSQKLTSRD--------SGPNGG---FQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSP 233
K+ +++ G N F+ G H K + + ++ +E
Sbjct: 264 TEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDN 323
Query: 234 VKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTS 293
+V+ + P++PP P AP+ P P+ + + +K +L + ++
Sbjct: 324 F---AVQINELDKDFPKPKKPPPPAKAPA----PKPELIAAEKKYFSLKPEEKDEKSTLE 376
Query: 294 GKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPM 353
K P P K TP KAS N + T+ +P E P PP+
Sbjct: 377 QKPSKPAAPQVPPKKPTPPTKAS---NLLRSSGTVYPKRP----------EKPVPPPPPI 423
Query: 354 DKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTR 387
K+ N +++ + + T E V +L E++ R
Sbjct: 424 AKI-NGEVSSISSKFET-EPVSKLKLDSEQLPLR 455
Score = 57.4 bits (137), Expect = 4e-08
Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 7/78 (8%)
Query: 75 YRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKK 134
Y V +DY DEL +R G++++ + K E+ GW EGE GRRG+FPDNFV K+
Sbjct: 4 YIVEYDYDAVHDDELTIRVGEIIRNVKKLQEE-GWLEGELNGRRGMFPDNFV------KE 56
Query: 135 LVPRKVVSRESAPIKEPK 152
+ +S PIK +
Sbjct: 57 IKRETEFKDDSLPIKRER 74
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 83.6 bits (205), Expect = 5e-16
Identities = 114/470 (24%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 128 PPPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRD 185
P P K P +E AP KEP PK PT K TT S T + P+
Sbjct: 247 PAPTTTKSAP--TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304
Query: 186 SQK----LTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-APSVK 240
+ K T ++ P K TP++ + +++E ++P + AP+
Sbjct: 305 TPKKPAPTTPKEPAPTTP-----------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPA 298
+ P P P E AP++ K P+P K P+P T + P +T+ P
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 299 PDKVPTPEKM-----VTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPM 353
K P+P TP++ A P T P+TP+ E +P P
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPK-----EPAPTTTKKPA 467
Query: 354 DKVP-NPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKED 412
P P + APT K LTP E+ T + K
Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE--------------------KPA 507
Query: 413 PSSQEE--AHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHP 470
P++ EE TPE P P P E K P K + P ++P P
Sbjct: 508 PTTPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAP 564
Query: 471 HEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELP------ 524
T P T +E AP ++P +E+ P +KE + + P
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPK 621
Query: 525 ------PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
PKE PKE P + A T +P P + + A L P
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 670
Score = 74.3 bits (181), Expect = 3e-13
Identities = 120/494 (24%), Positives = 173/494 (35%), Gaps = 60/494 (12%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
P P L P S+E++ + K+ +T T T+T G K TS ++ +
Sbjct: 123 PINPRPSLPPNSDTSKETS-LTVNKETTVETKETTTTNKQTSTDGKEKT-TSAKETQSIE 180
Query: 188 KLTSRDSGPNGGF----------QSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-A 236
K +++D P + G K TP++ + ++ +E + +K A
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 237 PSVKRTPMPDKT----ATPERP-------PAP----ENAPSSKKIPAPDKVPS----PEK 277
P+ + P P T TP+ P PAP E AP++ K PAP S P++
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 278 TLTLGDKASIPGNSTSGKIPAP--DKVPTPEKMVTPEDKASIPENSIIPEETLTVDK--- 332
K P T+ K PAP K PTP P P + E T K
Sbjct: 301 PAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 333 PSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQF 392
P+TP+ +P AP K P+P + APT K E +T
Sbjct: 358 PTTPKE--PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 393 HHFSSEEALQKVKYFVAKEDPS----SQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDS 448
K ++P+ + TP+ P P P K
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 449 SPRQAELKSGPASRPALEKPHPHEEATTLPEE-APSNDER----TPEEEAP--PNEQRPL 501
++ P + L P + A T PE+ AP+ E TPEE P P E P
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533
Query: 502 REEVLPKEGVASKEEVTLKEELP--PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQE 557
+ T KE P PKE PKE P + A T +P P + +
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPK 592
Query: 558 TLALPSLVPQNYTE 571
A L P E
Sbjct: 593 KPAPKELAPTTTKE 606
Score = 71.6 bits (174), Expect = 2e-12
Identities = 103/456 (22%), Positives = 176/456 (38%), Gaps = 53/456 (11%)
Query: 129 PPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDS 186
P P P + +AP KEP PK PT K TT +T+ T + +
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT---PKETAPTTPKGT 578
Query: 187 QKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPV-KAPSVKRTPMP 245
T ++ P + ++ + T T + S + + ++P AP+ + P P
Sbjct: 579 APTTLKEPAPTTPKKPAP-----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 633
Query: 246 DKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPAP---- 299
P AP++ K PAP K P+P++ K P ++TS K PAP
Sbjct: 634 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG--PTSTTSDK-PAPTTPK 690
Query: 300 DKVPTPEKM---VTPEDKA-SIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDK 355
+ PT K TP+ A + PE P T V P+T + ++ +SP P +
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748
Query: 356 VPNPKMAPLGDEAPTLEKVLTPELSEEEVST--RDDIQFHHFSSEEALQKVKYFVAKEDP 413
P PK + P + TP ++ E++T +D + + KE
Sbjct: 749 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 808
Query: 414 SSQE---EAHTPEAPPPQPPSSERCLGEMKCTLVRGDS-SPRQAELKSGPASRPALEKPH 469
++ E E+ ++ + K T ++ + +P+ K + + KP
Sbjct: 809 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP- 867
Query: 470 PHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEV 529
E T P++ +N + T P Q+P + PK+ ++K+ T+ PK
Sbjct: 868 ---EETAKPKDRATNSKAT-----TPKPQKPTK---APKKPTSTKKPKTMPRVRKPKTTP 916
Query: 530 APKE------EVPPIER---AFAQKTRPIKPPPDSQ 556
P++ E+ P R A Q T P+S+
Sbjct: 917 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 952
Score = 43.5 bits (101), Expect = 6e-04
Identities = 67/297 (22%), Positives = 108/297 (36%), Gaps = 47/297 (15%)
Query: 129 PPPIKKLVPRKVVSRESAPI-KEPKKLMPKTSL-PTVKKLATATTGPSKAKTSRTPSRD- 185
PPP V ++E I K P + P+ S PT K L + P T++TP+
Sbjct: 716 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-VPTTKTPAATK 774
Query: 186 -------SQKLTSRD---------SGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEE 229
K T RD + P ++ + + T T Q V+S +
Sbjct: 775 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ--VTSTTTQ 832
Query: 230 HSSPVKAPSVKRTPMPDKTATPER---------PPAPENAPSSKKIPAPDKVPSPEKTLT 280
++P K ++K T + K T ++ P P + + P P+K
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 892
Query: 281 LGDK-ASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERV 339
K S T ++ P PTP KM + + + P + I T +P+
Sbjct: 893 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELN-PTSRIAEAMLQTTTRPNQTPNS 951
Query: 340 FSVEESPAL--------EAPPMDKVPN---PKMAPLGDEAPTLEK---VLTPELSEE 382
VE +P E P M P+ P++ P D P + ++ P LS+E
Sbjct: 952 KLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1008
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 83.6 bits (205), Expect = 5e-16
Identities = 114/470 (24%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 128 PPPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRD 185
P P K P +E AP KEP PK PT K TT S T + P+
Sbjct: 288 PAPTTTKSAP--TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345
Query: 186 SQK----LTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-APSVK 240
+ K T ++ P K TP++ + +++E ++P + AP+
Sbjct: 346 TPKKPAPTTPKEPAPTTP-----------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPA 298
+ P P P E AP++ K P+P K P+P T + P +T+ P
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 299 PDKVPTPEKM-----VTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPM 353
K P+P TP++ A P T P+TP+ E +P P
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPK-----EPAPTTTKKPA 508
Query: 354 DKVP-NPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKED 412
P P + APT K LTP E+ T + K
Sbjct: 509 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE--------------------KPA 548
Query: 413 PSSQEE--AHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHP 470
P++ EE TPE P P P E K P K + P ++P P
Sbjct: 549 PTTPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAP 605
Query: 471 HEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELP------ 524
T P T +E AP ++P +E+ P +KE + + P
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPK 662
Query: 525 ------PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
PKE PKE P + A T +P P + + A L P
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 711
Score = 74.3 bits (181), Expect = 3e-13
Identities = 120/494 (24%), Positives = 173/494 (35%), Gaps = 60/494 (12%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
P P L P S+E++ + K+ +T T T+T G K TS ++ +
Sbjct: 164 PINPRPSLPPNSDTSKETS-LTVNKETTVETKETTTTNKQTSTDGKEKT-TSAKETQSIE 221
Query: 188 KLTSRDSGPNGGF----------QSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-A 236
K +++D P + G K TP++ + ++ +E + +K A
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 237 PSVKRTPMPDKT----ATPERP-------PAP----ENAPSSKKIPAPDKVPS----PEK 277
P+ + P P T TP+ P PAP E AP++ K PAP S P++
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 278 TLTLGDKASIPGNSTSGKIPAP--DKVPTPEKMVTPEDKASIPENSIIPEETLTVDK--- 332
K P T+ K PAP K PTP P P + E T K
Sbjct: 342 PAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 333 PSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQF 392
P+TP+ +P AP K P+P + APT K E +T
Sbjct: 399 PTTPKE--PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 393 HHFSSEEALQKVKYFVAKEDPS----SQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDS 448
K ++P+ + TP+ P P P K
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 514
Query: 449 SPRQAELKSGPASRPALEKPHPHEEATTLPEE-APSNDER----TPEEEAP--PNEQRPL 501
++ P + L P + A T PE+ AP+ E TPEE P P E P
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574
Query: 502 REEVLPKEGVASKEEVTLKEELP--PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQE 557
+ T KE P PKE PKE P + A T +P P + +
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPK 633
Query: 558 TLALPSLVPQNYTE 571
A L P E
Sbjct: 634 KPAPKELAPTTTKE 647
Score = 71.6 bits (174), Expect = 2e-12
Identities = 103/456 (22%), Positives = 176/456 (38%), Gaps = 53/456 (11%)
Query: 129 PPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDS 186
P P P + +AP KEP PK PT K TT +T+ T + +
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT---PKETAPTTPKGT 619
Query: 187 QKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPV-KAPSVKRTPMP 245
T ++ P + ++ + T T + S + + ++P AP+ + P P
Sbjct: 620 APTTLKEPAPTTPKKPAP-----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 674
Query: 246 DKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPAP---- 299
P AP++ K PAP K P+P++ K P ++TS K PAP
Sbjct: 675 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG--PTSTTSDK-PAPTTPK 731
Query: 300 DKVPTPEKM---VTPEDKA-SIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDK 355
+ PT K TP+ A + PE P T V P+T + ++ +SP P +
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789
Query: 356 VPNPKMAPLGDEAPTLEKVLTPELSEEEVST--RDDIQFHHFSSEEALQKVKYFVAKEDP 413
P PK + P + TP ++ E++T +D + + KE
Sbjct: 790 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 849
Query: 414 SSQE---EAHTPEAPPPQPPSSERCLGEMKCTLVRGDS-SPRQAELKSGPASRPALEKPH 469
++ E E+ ++ + K T ++ + +P+ K + + KP
Sbjct: 850 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP- 908
Query: 470 PHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEV 529
E T P++ +N + T P Q+P + PK+ ++K+ T+ PK
Sbjct: 909 ---EETAKPKDRATNSKAT-----TPKPQKPTK---APKKPTSTKKPKTMPRVRKPKTTP 957
Query: 530 APKE------EVPPIER---AFAQKTRPIKPPPDSQ 556
P++ E+ P R A Q T P+S+
Sbjct: 958 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 993
Score = 43.5 bits (101), Expect = 6e-04
Identities = 67/297 (22%), Positives = 108/297 (36%), Gaps = 47/297 (15%)
Query: 129 PPPIKKLVPRKVVSRESAPI-KEPKKLMPKTSL-PTVKKLATATTGPSKAKTSRTPSRD- 185
PPP V ++E I K P + P+ S PT K L + P T++TP+
Sbjct: 757 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-VPTTKTPAATK 815
Query: 186 -------SQKLTSRD---------SGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEE 229
K T RD + P ++ + + T T Q V+S +
Sbjct: 816 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ--VTSTTTQ 873
Query: 230 HSSPVKAPSVKRTPMPDKTATPER---------PPAPENAPSSKKIPAPDKVPSPEKTLT 280
++P K ++K T + K T ++ P P + + P P+K
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 933
Query: 281 LGDK-ASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERV 339
K S T ++ P PTP KM + + + P + I T +P+
Sbjct: 934 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELN-PTSRIAEAMLQTTTRPNQTPNS 992
Query: 340 FSVEESPAL--------EAPPMDKVPN---PKMAPLGDEAPTLEK---VLTPELSEE 382
VE +P E P M P+ P++ P D P + ++ P LS+E
Sbjct: 993 KLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1049
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 83.6 bits (205), Expect = 5e-16
Identities = 114/470 (24%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 128 PPPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRD 185
P P K P +E AP KEP PK PT K TT S T + P+
Sbjct: 340 PAPTTTKSAP--TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 186 SQK----LTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-APSVK 240
+ K T ++ P K TP++ + +++E ++P + AP+
Sbjct: 398 TPKKPAPTTPKEPAPTTP-----------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPA 298
+ P P P E AP++ K P+P K P+P T + P +T+ P
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 299 PDKVPTPEKM-----VTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPM 353
K P+P TP++ A P T P+TP+ E +P P
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPK-----EPAPTTTKKPA 560
Query: 354 DKVP-NPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKED 412
P P + APT K LTP E+ T + K
Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE--------------------KPA 600
Query: 413 PSSQEE--AHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHP 470
P++ EE TPE P P P E K P K + P ++P P
Sbjct: 601 PTTPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAP 657
Query: 471 HEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELP------ 524
T P T +E AP ++P +E+ P +KE + + P
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPK 714
Query: 525 ------PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
PKE PKE P + A T +P P + + A L P
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 763
Score = 74.3 bits (181), Expect = 3e-13
Identities = 120/494 (24%), Positives = 173/494 (35%), Gaps = 60/494 (12%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
P P L P S+E++ + K+ +T T T+T G K TS ++ +
Sbjct: 216 PINPRPSLPPNSDTSKETS-LTVNKETTVETKETTTTNKQTSTDGKEKT-TSAKETQSIE 273
Query: 188 KLTSRDSGPNGGF----------QSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-A 236
K +++D P + G K TP++ + ++ +E + +K A
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333
Query: 237 PSVKRTPMPDKT----ATPERP-------PAP----ENAPSSKKIPAPDKVPS----PEK 277
P+ + P P T TP+ P PAP E AP++ K PAP S P++
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393
Query: 278 TLTLGDKASIPGNSTSGKIPAP--DKVPTPEKMVTPEDKASIPENSIIPEETLTVDK--- 332
K P T+ K PAP K PTP P P + E T K
Sbjct: 394 PAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 333 PSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQF 392
P+TP+ +P AP K P+P + APT K E +T
Sbjct: 451 PTTPKE--PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 393 HHFSSEEALQKVKYFVAKEDPS----SQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDS 448
K ++P+ + TP+ P P P K
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 449 SPRQAELKSGPASRPALEKPHPHEEATTLPEE-APSNDER----TPEEEAP--PNEQRPL 501
++ P + L P + A T PE+ AP+ E TPEE P P E P
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626
Query: 502 REEVLPKEGVASKEEVTLKEELP--PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQE 557
+ T KE P PKE PKE P + A T +P P + +
Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPK 685
Query: 558 TLALPSLVPQNYTE 571
A L P E
Sbjct: 686 KPAPKELAPTTTKE 699
Score = 71.6 bits (174), Expect = 2e-12
Identities = 103/456 (22%), Positives = 176/456 (38%), Gaps = 53/456 (11%)
Query: 129 PPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDS 186
P P P + +AP KEP PK PT K TT +T+ T + +
Sbjct: 615 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT---PKETAPTTPKGT 671
Query: 187 QKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPV-KAPSVKRTPMP 245
T ++ P + ++ + T T + S + + ++P AP+ + P P
Sbjct: 672 APTTLKEPAPTTPKKPAP-----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726
Query: 246 DKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPAP---- 299
P AP++ K PAP K P+P++ K P ++TS K PAP
Sbjct: 727 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG--PTSTTSDK-PAPTTPK 783
Query: 300 DKVPTPEKM---VTPEDKA-SIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDK 355
+ PT K TP+ A + PE P T V P+T + ++ +SP P +
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 356 VPNPKMAPLGDEAPTLEKVLTPELSEEEVST--RDDIQFHHFSSEEALQKVKYFVAKEDP 413
P PK + P + TP ++ E++T +D + + KE
Sbjct: 842 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 901
Query: 414 SSQE---EAHTPEAPPPQPPSSERCLGEMKCTLVRGDS-SPRQAELKSGPASRPALEKPH 469
++ E E+ ++ + K T ++ + +P+ K + + KP
Sbjct: 902 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP- 960
Query: 470 PHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEV 529
E T P++ +N + T P Q+P + PK+ ++K+ T+ PK
Sbjct: 961 ---EETAKPKDRATNSKAT-----TPKPQKPTK---APKKPTSTKKPKTMPRVRKPKTTP 1009
Query: 530 APKE------EVPPIER---AFAQKTRPIKPPPDSQ 556
P++ E+ P R A Q T P+S+
Sbjct: 1010 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1045
Score = 53.1 bits (126), Expect = 8e-07
Identities = 87/379 (22%), Positives = 137/379 (36%), Gaps = 85/379 (22%)
Query: 229 EHSSPVKAPSVKRTPMPDKTA-----TPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGD 283
E +P PS K+ P P + T +R P P N +KK+ +++ + E +++
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEI-TEEHSVSENQ 123
Query: 284 KASIPGNSTSG---------------------KIPAPD-------KVPTPEKMVTPEDKA 315
++S +S+S K+ D K PTP+ V E +
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183
Query: 316 SIPENSIIPEETLTVDKPSTPERVFSVEESPAL-EAPPMDKVPNPKMAPLGDEAP----T 370
+ + T D +T V SP + A P++ P P + P D + T
Sbjct: 184 GLDNGDF---KVTTPDTSTTQHN--KVSTSPKITTAKPIN--PRPSLPPNSDTSKETSLT 236
Query: 371 LEKVLTPELSE-------------EEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQE 417
+ K T E E E+ ++ + Q +S + L +AK P ++
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 296
Query: 418 EAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTL 477
P P+ P+ T P +KS P + P E A T
Sbjct: 297 TTKGPALTTPKEPTPTTPKEPASTT----PKEPTPTTIKSAPTT--------PKEPAPTT 344
Query: 478 PEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVA---PKEE 534
+ AP+ TP+E AP + P PKE + T KE P + A PKE
Sbjct: 345 TKSAPT----TPKEPAPTTTKEP--APTTPKEPAPT----TTKEPAPTTTKSAPTTPKEP 394
Query: 535 VPPIERAFAQKTRPIKPPP 553
P + A T P +P P
Sbjct: 395 APTTPKKPA-PTTPKEPAP 412
Score = 43.5 bits (101), Expect = 6e-04
Identities = 67/297 (22%), Positives = 108/297 (36%), Gaps = 47/297 (15%)
Query: 129 PPPIKKLVPRKVVSRESAPI-KEPKKLMPKTSL-PTVKKLATATTGPSKAKTSRTPSRD- 185
PPP V ++E I K P + P+ S PT K L + P T++TP+
Sbjct: 809 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-VPTTKTPAATK 867
Query: 186 -------SQKLTSRD---------SGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEE 229
K T RD + P ++ + + T T Q V+S +
Sbjct: 868 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ--VTSTTTQ 925
Query: 230 HSSPVKAPSVKRTPMPDKTATPER---------PPAPENAPSSKKIPAPDKVPSPEKTLT 280
++P K ++K T + K T ++ P P + + P P+K
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 985
Query: 281 LGDK-ASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERV 339
K S T ++ P PTP KM + + + P + I T +P+
Sbjct: 986 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELN-PTSRIAEAMLQTTTRPNQTPNS 1044
Query: 340 FSVEESPAL--------EAPPMDKVPN---PKMAPLGDEAPTLEK---VLTPELSEE 382
VE +P E P M P+ P++ P D P + ++ P LS+E
Sbjct: 1045 KLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1101
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 83.6 bits (205), Expect = 5e-16
Identities = 114/470 (24%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 128 PPPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRD 185
P P K P +E AP KEP PK PT K TT S T + P+
Sbjct: 381 PAPTTTKSAP--TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 186 SQK----LTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-APSVK 240
+ K T ++ P K TP++ + +++E ++P + AP+
Sbjct: 439 TPKKPAPTTPKEPAPTTP-----------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPA 298
+ P P P E AP++ K P+P K P+P T + P +T+ P
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 299 PDKVPTPEKM-----VTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPM 353
K P+P TP++ A P T P+TP+ E +P P
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPK-----EPAPTTTKKPA 601
Query: 354 DKVP-NPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKED 412
P P + APT K LTP E+ T + K
Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE--------------------KPA 641
Query: 413 PSSQEE--AHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHP 470
P++ EE TPE P P P E K P K + P ++P P
Sbjct: 642 PTTPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAP 698
Query: 471 HEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELP------ 524
T P T +E AP ++P +E+ P +KE + + P
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPK 755
Query: 525 ------PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
PKE PKE P + A T +P P + + A L P
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAP 804
Score = 74.3 bits (181), Expect = 3e-13
Identities = 120/494 (24%), Positives = 173/494 (35%), Gaps = 60/494 (12%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
P P L P S+E++ + K+ +T T T+T G K TS ++ +
Sbjct: 257 PINPRPSLPPNSDTSKETS-LTVNKETTVETKETTTTNKQTSTDGKEKT-TSAKETQSIE 314
Query: 188 KLTSRDSGPNGGF----------QSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-A 236
K +++D P + G K TP++ + ++ +E + +K A
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374
Query: 237 PSVKRTPMPDKT----ATPERP-------PAP----ENAPSSKKIPAPDKVPS----PEK 277
P+ + P P T TP+ P PAP E AP++ K PAP S P++
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434
Query: 278 TLTLGDKASIPGNSTSGKIPAP--DKVPTPEKMVTPEDKASIPENSIIPEETLTVDK--- 332
K P T+ K PAP K PTP P P + E T K
Sbjct: 435 PAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 333 PSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQF 392
P+TP+ +P AP K P+P + APT K E +T
Sbjct: 492 PTTPKE--PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 393 HHFSSEEALQKVKYFVAKEDPS----SQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDS 448
K ++P+ + TP+ P P P K
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 449 SPRQAELKSGPASRPALEKPHPHEEATTLPEE-APSNDER----TPEEEAP--PNEQRPL 501
++ P + L P + A T PE+ AP+ E TPEE P P E P
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 667
Query: 502 REEVLPKEGVASKEEVTLKEELP--PKE--EVAPKEEVPPIERAFAQKTRPIKPPPDSQE 557
+ T KE P PKE PKE P + A T +P P + +
Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPK 726
Query: 558 TLALPSLVPQNYTE 571
A L P E
Sbjct: 727 KPAPKELAPTTTKE 740
Score = 71.6 bits (174), Expect = 2e-12
Identities = 103/456 (22%), Positives = 176/456 (38%), Gaps = 53/456 (11%)
Query: 129 PPPIKKLVPRKVVSRESAPI--KEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDS 186
P P P + +AP KEP PK PT K TT +T+ T + +
Sbjct: 656 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT---PKETAPTTPKGT 712
Query: 187 QKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPV-KAPSVKRTPMP 245
T ++ P + ++ + T T + S + + ++P AP+ + P P
Sbjct: 713 APTTLKEPAPTTPKKPAP-----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767
Query: 246 DKTATPERPPAPENAPSSKKIPAPD--KVPSPEKTLTLGDKASIPGNSTSGKIPAP---- 299
P AP++ K PAP K P+P++ K P ++TS K PAP
Sbjct: 768 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG--PTSTTSDK-PAPTTPK 824
Query: 300 DKVPTPEKM---VTPEDKA-SIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDK 355
+ PT K TP+ A + PE P T V P+T + ++ +SP P +
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 356 VPNPKMAPLGDEAPTLEKVLTPELSEEEVST--RDDIQFHHFSSEEALQKVKYFVAKEDP 413
P PK + P + TP ++ E++T +D + + KE
Sbjct: 883 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 942
Query: 414 SSQE---EAHTPEAPPPQPPSSERCLGEMKCTLVRGDS-SPRQAELKSGPASRPALEKPH 469
++ E E+ ++ + K T ++ + +P+ K + + KP
Sbjct: 943 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP- 1001
Query: 470 PHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEV 529
E T P++ +N + T P Q+P + PK+ ++K+ T+ PK
Sbjct: 1002 ---EETAKPKDRATNSKAT-----TPKPQKPTK---APKKPTSTKKPKTMPRVRKPKTTP 1050
Query: 530 APKE------EVPPIER---AFAQKTRPIKPPPDSQ 556
P++ E+ P R A Q T P+S+
Sbjct: 1051 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1086
Score = 53.1 bits (126), Expect = 8e-07
Identities = 87/379 (22%), Positives = 137/379 (36%), Gaps = 85/379 (22%)
Query: 229 EHSSPVKAPSVKRTPMPDKTA-----TPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGD 283
E +P PS K+ P P + T +R P P N +KK+ +++ + E +++
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEI-TEEHSVSENQ 164
Query: 284 KASIPGNSTSG---------------------KIPAPD-------KVPTPEKMVTPEDKA 315
++S +S+S K+ D K PTP+ V E +
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224
Query: 316 SIPENSIIPEETLTVDKPSTPERVFSVEESPAL-EAPPMDKVPNPKMAPLGDEAP----T 370
+ + T D +T V SP + A P++ P P + P D + T
Sbjct: 225 GLDNGDF---KVTTPDTSTTQHN--KVSTSPKITTAKPIN--PRPSLPPNSDTSKETSLT 277
Query: 371 LEKVLTPELSE-------------EEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQE 417
+ K T E E E+ ++ + Q +S + L +AK P ++
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 337
Query: 418 EAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTL 477
P P+ P+ T P +KS P + P E A T
Sbjct: 338 TTKGPALTTPKEPTPTTPKEPASTT----PKEPTPTTIKSAPTT--------PKEPAPTT 385
Query: 478 PEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVA---PKEE 534
+ AP+ TP+E AP + P PKE + T KE P + A PKE
Sbjct: 386 TKSAPT----TPKEPAPTTTKEP--APTTPKEPAPT----TTKEPAPTTTKSAPTTPKEP 435
Query: 535 VPPIERAFAQKTRPIKPPP 553
P + A T P +P P
Sbjct: 436 APTTPKKPA-PTTPKEPAP 453
Score = 43.5 bits (101), Expect = 6e-04
Identities = 67/297 (22%), Positives = 108/297 (36%), Gaps = 47/297 (15%)
Query: 129 PPPIKKLVPRKVVSRESAPI-KEPKKLMPKTSL-PTVKKLATATTGPSKAKTSRTPSRD- 185
PPP V ++E I K P + P+ S PT K L + P T++TP+
Sbjct: 850 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-VPTTKTPAATK 908
Query: 186 -------SQKLTSRD---------SGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEE 229
K T RD + P ++ + + T T Q V+S +
Sbjct: 909 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ--VTSTTTQ 966
Query: 230 HSSPVKAPSVKRTPMPDKTATPER---------PPAPENAPSSKKIPAPDKVPSPEKTLT 280
++P K ++K T + K T ++ P P + + P P+K
Sbjct: 967 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 1026
Query: 281 LGDK-ASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERV 339
K S T ++ P PTP KM + + + P + I T +P+
Sbjct: 1027 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELN-PTSRIAEAMLQTTTRPNQTPNS 1085
Query: 340 FSVEESPAL--------EAPPMDKVPN---PKMAPLGDEAPTLEK---VLTPELSEE 382
VE +P E P M P+ P++ P D P + ++ P LS+E
Sbjct: 1086 KLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1142
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 83.6 bits (205), Expect = 5e-16
Identities = 120/500 (24%), Positives = 193/500 (38%), Gaps = 93/500 (18%)
Query: 138 RKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPN 197
+KV S E P K P P + + ATA P A+ + + S + T
Sbjct: 250 KKVASAEIEPPSTEK--FPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAAT 307
Query: 198 GGFQSGGSYHP--GRKRSKTQTPQQRSVSSQEEEHSSPVKA----PSVKRTPMPDKTATP 251
++ P + + P + S EE S + A PS + +P + A
Sbjct: 308 AVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEI 367
Query: 252 ERPPAPEN----------APSSKKIP--------------APDKVPSPEKTLTLGDKASI 287
PPA ++ +PS++K P AP KV P TL D +
Sbjct: 368 LPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPL 427
Query: 288 PGNSTSGKIPAPDKVPTPEK--------MVTPEDKASIPENSIIPEETLTVDKPSTPERV 339
P++ P E M TP ++A S +P+ET T ++ S ++
Sbjct: 428 ----------LPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKET-TAEEASAEIQL 476
Query: 340 FSVEESPALEAPPMDKVPNPKMAPLGDEAPTLE---KVLTPELSEEEVSTRDDIQFHHFS 396
+ E PP D+ P +PL +E E +V +P L+EE +
Sbjct: 477 LAATE------PPADETPAEARSPLSEETSAEEAHAEVQSP-LAEET------------T 517
Query: 397 SEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRG---DSSPRQA 453
+EEA +++ A E P+ + A ++P + S+E E++ +G + +P +
Sbjct: 518 AEEASAEIQLLAAIEAPADETPAEA-QSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLEL 576
Query: 454 ELKSGP--------------ASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQR 499
+ SG A+ A + P E EEAP+ + P EEAP Q
Sbjct: 577 QPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 636
Query: 500 PLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQ-KTRPIKPPPDSQET 558
P EE + EE + + PP EE + + PP E A A+ ++ P + P +ET
Sbjct: 637 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETP-IEET 695
Query: 559 LALPSLVPQNYTENKNEGVD 578
LA P + + VD
Sbjct: 696 LAAVHSPPADDVPAEEASVD 715
Score = 64.3 bits (155), Expect = 3e-10
Identities = 112/486 (23%), Positives = 183/486 (37%), Gaps = 69/486 (14%)
Query: 175 KAKTSRTPSRDSQKLTSRDSGPNG--GFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSS 232
K K P S K T R +G G S +Y R S+ Q + QE S
Sbjct: 13 KKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWTKRKHGQEMTSKS 72
Query: 233 ---------PVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGD 283
+ V+ T +P++ + R A E S + + P +PS + +
Sbjct: 73 LQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQ 132
Query: 284 KASIPGNSTSGKIPAPDKVPTPEKMVTPEDK---ASIPENSIIPEETLTVDKPSTPERVF 340
+ S G T IP +KV ++ E + S P++S + + K + ++F
Sbjct: 133 QTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDAL-KHKSSGKIF 191
Query: 341 SVEE---SPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSS 397
+ E PA + N E K P L E+E+ R+++
Sbjct: 192 ASEHPEFQPATNSNEEIGQKNISRTSFTQET----KKGPPVLLEDEL--REEVTVPVVQE 245
Query: 398 EEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKS 457
A++KV + +PPS+E+ +++ LV +A K+
Sbjct: 246 GSAVKKV------------------ASAEIEPPSTEKFPAKIQPPLV------EEATAKA 281
Query: 458 GPASRPALE---KPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLRE---EVLPKEGV 511
P RPA E + P E T E A + E + + + PP E+ PL E E+ P
Sbjct: 282 EP--RPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAE 339
Query: 512 ASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTE 571
S L E LPP E +P EE PP E I PPP ++++ ++ L
Sbjct: 340 ESPSVELLAEILPPSAEESPSEE-PPAE---------ILPPP-AEKSPSVELLGEIRSPS 388
Query: 572 NKNEGVDVTSLRGEVESLRRALELMEVQLERKLTDIWEELKSE--KEQRRRLEVQVMQGT 629
+ ++V L E ++ +E L D+ L E +E+ R L++ T
Sbjct: 389 AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMET 448
Query: 630 QKSQTP 635
+ P
Sbjct: 449 PAEEAP 454
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 82.8 bits (203), Expect = 9e-16
Identities = 92/330 (27%), Positives = 135/330 (40%), Gaps = 74/330 (22%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV-LPPPPIKK 134
+V+F Y+ + DEL ++ GD+V +++K D GWWEGE GRRGVFPDNFV L PP +K
Sbjct: 236 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEK 295
Query: 135 LVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDS 194
R PKK P S P +K+ A T K + + P + L
Sbjct: 296 EGNR------------PKK-PPPPSAPVIKQ--GAGTTERKHEIKKIPPERPEML----- 335
Query: 195 GPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERP 254
P R K + ++ + Q+ S P P + P P KT + RP
Sbjct: 336 -------------PNRTEEKERPEREPKLDLQKP--SVPAIPP---KKPRPPKTNSLSRP 377
Query: 255 PA-PENAPSSKKIPAPDKVPSPEKTLTLGD--KASIPGNSTSGKIPA------------- 298
A P P P T T GD K + G+S SG +
Sbjct: 378 GALPPRRPER---------PVGPLTHTRGDSPKIDLAGSSLSGILDKDLSDRSNDIDLEG 428
Query: 299 -PDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVP 357
V + EK+ P P ++LT S+P+ + +SP +P DK
Sbjct: 429 FDSVVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD----IFDSP---SPEEDKEE 481
Query: 358 NPKMAPLGDEA--PTLEKVLTPELSEEEVS 385
+ +A G +A T + V ++S+ + S
Sbjct: 482 HISLAHRGVDASKKTSKTVTISQVSDNKAS 511
Score = 61.6 bits (148), Expect = 2e-09
Identities = 136/612 (22%), Positives = 219/612 (35%), Gaps = 122/612 (19%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKL 135
+V F Y P+ DEL L+ GD+++V+ + E GWWEG G+ G+FP NF+
Sbjct: 67 QVAFSYLPQNDDELELKVGDIIEVVGEVEE--GWWEGVLNGKTGMFPSNFI--------- 115
Query: 136 VPRKVVSRESAPIK-EPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDS 194
K +S ES + + + K+SL TTG S + DS +++
Sbjct: 116 ---KELSGESDELGISQDEQLSKSSL-------RETTG------SESDGGDSS--STKSE 157
Query: 195 GPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERP 254
G NG + + Q + + V + P+K + ++ E
Sbjct: 158 GANGTVAT----------AAIQPKKVKGVGFGDIFKDKPIK--------LRPRSIEVEND 199
Query: 255 PAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPE-D 313
P KK+PA P KT + S + K+ P + +++ E D
Sbjct: 200 FLPVEKTIGKKLPATTATPDSSKT----EMDSRTKSKDYCKVIFPYEAQNDDELTIKEGD 255
Query: 314 KASIPENSIIP----EETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAP-LGDEA 368
++ I E L + P+ + + K P P AP + A
Sbjct: 256 IVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKPPPPSAPVIKQGA 315
Query: 369 PTLE-----KVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFV---AKEDPSSQEEAH 420
T E K + PE E + ++ + + LQK K P
Sbjct: 316 GTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPPKKPRPPKTNSLS 375
Query: 421 TPEAPPPQPPSSERCLGEMKCTLVRGDS------------------SPRQAEL------- 455
P A PP+ P ER +G + T RGDS S R ++
Sbjct: 376 RPGALPPRRP--ERPVGPL--THTRGDSPKIDLAGSSLSGILDKDLSDRSNDIDLEGFDS 431
Query: 456 ---KSGPASRPALEKPH------PHEEATTLPEEAPS-NDERTPEEEAPPN---EQRPLR 502
+ S P +P P + T+ +P D +PEE+ + R +
Sbjct: 432 VVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPDIFDSPSPEEDKEEHISLAHRGVD 491
Query: 503 EEVLPKEGVASKEEVTLKEELPPKEEV--------APKEEVPPIERAFAQKTRPIKP-PP 553
+ V + K LPPK AP P + + T + P
Sbjct: 492 ASKKTSKTVTISQVSDNKASLPPKPGTMAAGGGGPAPLSSAAPSPLSSSLGTAGHRANSP 551
Query: 554 DSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQLERKLTDIWEELKS 613
T P + P ++ V LR +V LR +E M+ Q +R++ + EL
Sbjct: 552 SLFGTEGKPKMEPAASSQ-----AAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDE 606
Query: 614 EKEQRRRLEVQV 625
EK+ R RL+++V
Sbjct: 607 EKKIRLRLQMEV 618
Score = 51.6 bits (122), Expect = 2e-06
Identities = 88/360 (24%), Positives = 129/360 (35%), Gaps = 76/360 (21%)
Query: 5 IEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPD 64
I+ GWW G+ NG+ G FP NFV+LL PD P++PP S P
Sbjct: 265 IDVGWWEGELNGRRGVFPDNFVKLLP--------PDFEKEGNRPKKPPP------PSAPV 310
Query: 65 YLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDN 124
Q E + PE P+ +L TE+K E E
Sbjct: 311 IKQGAGTTERKHEIKKIPPERPE-----------MLPNRTEEKERPERE---------PK 350
Query: 125 FVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSK----AKTSR 180
L P + + P+K ++ + P L P+ V L T T G S A +S
Sbjct: 351 LDLQKPSVPAIPPKKPRPPKTNSLSRPGALPPRRPERPVGPL-THTRGDSPKIDLAGSSL 409
Query: 181 TPSRDSQKLTSRDSGPNGGFQSGGS-----YHPGRKRSKT--QTPQQRSVSSQEEEHSSP 233
+ D + GF S S HP R K + P +S++ SS
Sbjct: 410 SGILDKDLSDRSNDIDLEGFDSVVSSTEKLSHPTTSRPKATGRRPPSQSLT------SSS 463
Query: 234 VKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLG----DKASIPG 289
+ +P + +P P++ A +SKK KT+T+ +KAS+P
Sbjct: 464 LSSPDIFDSPSPEEDKEEHISLAHRGVDASKK---------TSKTVTISQVSDNKASLP- 513
Query: 290 NSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALE 349
G + A P P P P +S + + PS +F E P +E
Sbjct: 514 -PKPGTMAAGGGGPAPLSSAAPS-----PLSSSLGTAGHRANSPS----LFGTEGKPKME 563
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 82.8 bits (203), Expect = 9e-16
Identities = 92/330 (27%), Positives = 135/330 (40%), Gaps = 74/330 (22%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV-LPPPPIKK 134
+V+F Y+ + DEL ++ GD+V +++K D GWWEGE GRRGVFPDNFV L PP +K
Sbjct: 273 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEK 332
Query: 135 LVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDS 194
R PKK P S P +K+ A T K + + P + L
Sbjct: 333 EGNR------------PKK-PPPPSAPVIKQ--GAGTTERKHEIKKIPPERPEML----- 372
Query: 195 GPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERP 254
P R K + ++ + Q+ S P P + P P KT + RP
Sbjct: 373 -------------PNRTEEKERPEREPKLDLQKP--SVPAIPP---KKPRPPKTNSLSRP 414
Query: 255 PA-PENAPSSKKIPAPDKVPSPEKTLTLGD--KASIPGNSTSGKIPA------------- 298
A P P P T T GD K + G+S SG +
Sbjct: 415 GALPPRRPER---------PVGPLTHTRGDSPKIDLAGSSLSGILDKDLSDRSNDIDLEG 465
Query: 299 -PDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVP 357
V + EK+ P P ++LT S+P+ + +SP +P DK
Sbjct: 466 FDSVVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD----IFDSP---SPEEDKEE 518
Query: 358 NPKMAPLGDEA--PTLEKVLTPELSEEEVS 385
+ +A G +A T + V ++S+ + S
Sbjct: 519 HISLAHRGVDASKKTSKTVTISQVSDNKAS 548
Score = 82.0 bits (201), Expect = 2e-15
Identities = 160/694 (23%), Positives = 253/694 (36%), Gaps = 137/694 (19%)
Query: 2 IKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRP----PKLSSL 57
I++ + GWW G+ NG+ G FP NFV + P + P++P P +SL
Sbjct: 29 IRKEDGGWWEGQINGRRGLFPDNFVREIKKEMKK-----DPLTNKAPEKPLHEVPSGNSL 83
Query: 58 AYDSPPDYLQTVSHPEVYR----VLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGE 113
S L+T E R V F Y P+ DEL L+ GD+++V+ + E GWWEG
Sbjct: 84 L--SSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEE--GWWEGV 139
Query: 114 CQGRRGVFPDNFVLPPPPIKKLVPRKVVSRESAPIK-EPKKLMPKTSLPTVKKLATATTG 172
G+ G+FP NF+ K +S ES + + + K+SL TTG
Sbjct: 140 LNGKTGMFPSNFI------------KELSGESDELGISQDEQLSKSSL-------RETTG 180
Query: 173 PSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSS 232
S + DS +++ G NG + + Q + + V +
Sbjct: 181 ------SESDGGDSS--STKSEGANGTVAT----------AAIQPKKVKGVGFGDIFKDK 222
Query: 233 PVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNST 292
P+K + ++ E P KK+PA P KT + S +
Sbjct: 223 PIK--------LRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKT----EMDSRTKSKD 270
Query: 293 SGKIPAPDKVPTPEKMVTPE-DKASIPENSIIP----EETLTVDKPSTPERVFSVEESPA 347
K+ P + +++ E D ++ I E L + P+ +
Sbjct: 271 YCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDF 330
Query: 348 LEAPPMDKVPNPKMAP-LGDEAPTLE-----KVLTPELSEEEVSTRDDIQFHHFSSEEAL 401
+ K P P AP + A T E K + PE E + ++ + + L
Sbjct: 331 EKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDL 390
Query: 402 QKVKYFV---AKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDS---------- 448
QK K P P A PP+ P ER +G + T RGDS
Sbjct: 391 QKPSVPAIPPKKPRPPKTNSLSRPGALPPRRP--ERPVGPL--THTRGDSPKIDLAGSSL 446
Query: 449 --------SPRQAEL----------KSGPASRPALEKPH------PHEEATTLPEEAPS- 483
S R ++ + S P +P P + T+ +P
Sbjct: 447 SGILDKDLSDRSNDIDLEGFDSVVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPDI 506
Query: 484 NDERTPEEEAPPN---EQRPLREEVLPKEGVASKEEVTLKEELPPKEEV--------APK 532
D +PEE+ + R + + V + K LPPK AP
Sbjct: 507 FDSPSPEEDKEEHISLAHRGVDASKKTSKTVTISQVSDNKASLPPKPGTMAAGGGGPAPL 566
Query: 533 EEVPPIERAFAQKTRPIKP-PPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRR 591
P + + T + P T P + P ++ V LR +V LR
Sbjct: 567 SSAAPSPLSSSLGTAGHRANSPSLFGTEGKPKMEPAASSQ-----AAVEELRTQVRELRS 621
Query: 592 ALELMEVQLERKLTDIWEELKSEKEQRRRLEVQV 625
+E M+ Q +R++ + EL EK+ R RL+++V
Sbjct: 622 IIETMKDQQKREIKQLLSELDEEKKIRLRLQMEV 655
Score = 61.2 bits (147), Expect = 3e-09
Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 12/95 (12%)
Query: 77 VLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLV 136
V FDYQ + DEL + G+++ + K ED GWWEG+ GRRG+FPDNFV
Sbjct: 6 VEFDYQAQHDDELTISVGEIITNIRK--EDGGWWEGQINGRRGLFPDNFVRE-------- 55
Query: 137 PRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATT 171
+K + ++ K P+K P +P+ L ++ T
Sbjct: 56 IKKEMKKDPLTNKAPEK--PLHEVPSGNSLLSSET 88
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 80.9 bits (198), Expect = 3e-15
Identities = 108/438 (24%), Positives = 161/438 (36%), Gaps = 75/438 (17%)
Query: 146 APIKEPKKLMPKTSLPTVKKLATATTG--PSKAKTSRTPSRDSQKLTSRDSGPNGGFQSG 203
A + P++ P + ++ +A G P A + T +T D P G
Sbjct: 924 AAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVP-----ITEEDGTPEGPVTPA 978
Query: 204 GSYH----PGRKRSKTQTPQQRSVSSQE----EEHSSPVKAPSVKRTPMPDKTATPERPP 255
+ H P + TP++ + + EE +SP A P A P PP
Sbjct: 979 TTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--PP 1036
Query: 256 APENAPSSKKIPAPDK-------VPSPEKTLTLGDKASIPGNSTS--GKIPAPDK----- 301
+P++ +P P++ VP+PE+ + P TS +P P++
Sbjct: 1037 EEPTSPAAA-VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
Query: 302 --VPTPEKMVTPEDKASIPENSIIPEETL-TVDKPSTPERVFSVEESPALEAPPMDKVPN 358
VPTPE+ +P PE P + T ++P++P E PA AP VP
Sbjct: 1096 AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP---AVPT 1152
Query: 359 PKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEE 418
P+ + A V TPE S + + E+ E+P+S
Sbjct: 1153 PE-----ESASAAVAVPTPEESASPAAAVP-------TPAESASFAAVVATLEEPTS--- 1197
Query: 419 AHTPEAPPPQP------------PSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALE 466
P A P P P++ E +L S+P E S A+ P LE
Sbjct: 1198 ---PAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE--EPTSPAAAVPTLE 1252
Query: 467 KPHPHEEATTLPEE--APSNDERTPEEEAPPNEQ-RPLREEVLPKEGVASKEEVTLKEEL 523
+P A PEE +P+ TPEE A P L E P V + E +
Sbjct: 1253 EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAAS 1312
Query: 524 PPKEEV--APKEEVPPIE 539
P EV P VPP+E
Sbjct: 1313 VPTPEVPAIPAAAVPPME 1330
Score = 65.1 bits (157), Expect = 2e-10
Identities = 97/375 (25%), Positives = 141/375 (37%), Gaps = 67/375 (17%)
Query: 228 EEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPD-------KVPSPEKTLT 280
EE ++ PS K A P+PE S +PAP+ VP P + +
Sbjct: 825 EEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDIL 884
Query: 281 LGDKASIPGNS-TSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERV 339
+ S+ T+ + AP++ P V+ +PE T V S+PE
Sbjct: 885 VASIVSLEEEDVTAAAVSAPERATVPAVTVS------------VPEGTAAVAAVSSPE-- 930
Query: 340 FSVEESPALEA----PPMDKVP--NPKMA------PLGDEAPTLEKVLTPELSEEEVSTR 387
E +PA+ A M V +P+ A P+ +E T E +TP +
Sbjct: 931 ---ETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
Query: 388 DDIQFHHFSSEEALQKVKYFVAKEDPSS-------QEEAHTPEA--PPPQPPSSERCLGE 438
D + EE E+P+S EE +P A PPP+ P+S
Sbjct: 988 DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA--- 1044
Query: 439 MKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE--APSNDERTPEEEAPPN 496
+ P E S A+ P E+P A PEE +P+ TPEE P
Sbjct: 1045 ---------AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
Query: 497 EQRPLREE-VLPKEGVASKEE-VTLKEELP-PKEEVAPKEEVP-PIERAFAQKTRPIKPP 552
P EE P V + EE + +P P+E +P VP P E AF P P
Sbjct: 1096 AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF---PAPAVPT 1152
Query: 553 PDSQETLALPSLVPQ 567
P+ + A+ P+
Sbjct: 1153 PEESASAAVAVPTPE 1167
Score = 35.4 bits (80), Expect = 0.16
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 39/181 (21%)
Query: 218 PQQRSVSSQEEEHSSPVKAPSVKRTP--MPDKTATPERPPAP--------ENAPSSKKIP 267
P ++ + EE +SP + P + + PE P +P E S+ +
Sbjct: 1203 PTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL 1262
Query: 268 APDKVPSPEKTLTLGDKASIPGNSTSG-KIPAPDK--VPTPEKMVTPEDKASIPENSIIP 324
P+++ SP ++ ++ + P + S + PA VPTPE P AS+P
Sbjct: 1263 TPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIP--AASVP------ 1314
Query: 325 EETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPT----LEKVLTPELS 380
TPE V PA PPM++V + LG A T + + TP L
Sbjct: 1315 ----------TPE----VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360
Query: 381 E 381
E
Sbjct: 1361 E 1361
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 76.3 bits (186), Expect = 8e-14
Identities = 158/692 (22%), Positives = 264/692 (38%), Gaps = 108/692 (15%)
Query: 6 EDGWWLGKKNGQLGAFPSNFVELLDSGP-------PSLGNPDMPSVSPGPQRPPKLSSLA 58
E GW+ G+ G+ G FP FVELL GP S GN D V+ P +
Sbjct: 179 EPGWFEGELEGRRGIFPEGFVELL--GPLRTVDESVSSGNQDDCIVNGEVDTPVGEEEIG 236
Query: 59 YDSPPDYLQTVSHPEVYRV-LFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGR 117
D + P Y V L+ +Q P+EL GD +++L+ T ED GW EG +GR
Sbjct: 237 PDEDEE------EPGTYGVALYRFQALEPNELDFEVGDKIRILA-TLED-GWLEGSLKGR 288
Query: 118 RGVFPDNFVLPPPPIKKLVP-RKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKA 176
G+FP FV KL P +V + P + +P+TSL ++ T +
Sbjct: 289 TGIFPYRFV-------KLCPDTRVEETMALPQEGSLARIPETSLDCLEN--TLGVEEQRH 339
Query: 177 KTSRTPSRDSQKLTSR-DSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK 235
+TS + + + S + P G S Y R + + S E P+
Sbjct: 340 ETSDHEAEEPDCIISEAPTSPLGHLTS--EYDTDRNSYQDEDTAGGPPRSPGVEWEMPLA 397
Query: 236 APSVKRTPMPDKTATPERPPAP---------------ENAPSSKKIPAPDKVPSPEKTLT 280
S P +P P + P S++ PD +P +T
Sbjct: 398 TDSPTSDPTEVVNGISSQPQVPFHPNLQKSQYYSTVGGSHPHSEQY--PDLLPLEART-- 453
Query: 281 LGDKASIPGNSTSGKIPAPDKVPTP---------EKMVTPEDKASIPENSIIPEETLTVD 331
D AS+P ++ K P ++V P + S P+ + T
Sbjct: 454 -RDYASLPPKRMYSQLKTLQKPVLPLYRGSSVSASRVVKP--RQSSPQLHNLASYT---- 506
Query: 332 KPSTPERVFSVEESPALEAPPMDK--VPNPKMAPLGDEAPTLEKVLTPELSEEEVS---- 385
K V+S+ E ++ P + V GD + L+ LT +L E E S
Sbjct: 507 KKHHTSSVYSISERLEMKPGPQAQGLVMEAATHSQGDGSTDLDSKLTQQLIEFEKSLAGP 566
Query: 386 -TRDDIQFHHF------SSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSS------ 432
T D HF S ++ ++ + +++ + +A P P P P S
Sbjct: 567 GTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPPRPCTPVSTSPHLL 626
Query: 433 -ERCLGEMKCTLVRGDSS---PRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERT 488
++ L +VR P A+ ++ S L + P E TL +E P + R+
Sbjct: 627 VDQNLKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSRHRPTCE--TLEKEGPGHMGRS 684
Query: 489 PEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRP 548
++ +P EE+ + S+ + L L K++ E + A+
Sbjct: 685 LDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQD----------ESSRAETLED 734
Query: 549 IKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQLERKLTDIW 608
+K + E+L + + T ++ + + G V A + LE++ I
Sbjct: 735 LKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVS----AENPEQRMLEKRAKVIE 790
Query: 609 EELKSEKEQRRRLEV---QVMQGTQKSQTPRV 637
E L++E++ R LE+ ++M Q++Q P +
Sbjct: 791 ELLQTERDYIRDLEMCIERIMVPMQQAQVPNI 822
Score = 48.9 bits (115), Expect = 1e-05
Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 126
R L + +EL R GDV+ ++ + GW+EGE +GRRG+FP+ FV
Sbjct: 151 RALMGLSAQLDEELDFREGDVITIIG--VPEPGWFEGELEGRRGIFPEGFV 199
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 37/123 (30%)
Query: 5 IEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPD 64
+++ W LGKK G FPS+FVE++ +PS+ G +
Sbjct: 35 VDEFWLLGKKEDVTGQFPSSFVEIV----------TIPSLKEGER--------------- 69
Query: 65 YLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEG-ECQGRRGVFPD 123
++ + ++ + D L L RGD+V + T GW +G C G RG FP
Sbjct: 70 ---------LFVCICEFTSQELDNLPLHRGDLVILDGIPT--AGWLQGRSCWGARGFFPS 118
Query: 124 NFV 126
+ V
Sbjct: 119 SCV 121
Score = 38.5 bits (88), Expect = 0.019
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 74 VYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 126
V R +FD+ P +EL L GD+++VL+ D+ W G+ + G FP +FV
Sbjct: 6 VVRAIFDFCPSVSEELPLFVGDIIEVLA--VVDEFWLLGKKEDVTGQFPSSFV 56
Score = 37.4 bits (85), Expect = 0.043
Identities = 15/56 (26%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 73 EVYRVLFDYQPEAPDELALRRGDVVKVLS--KTTEDKGWWEGECQGRRGVFPDNFV 126
+VY ++ ++ P+EL++ +K+L T + WW E G++G P N++
Sbjct: 1516 QVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYI 1571
Score = 30.4 bits (67), Expect = 5.3
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVEL 28
++ +EDGW G G+ G FP FV+L
Sbjct: 272 ILATLEDGWLEGSLKGRTGIFPYRFVKL 299
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 74.7 bits (182), Expect = 2e-13
Identities = 110/464 (23%), Positives = 160/464 (34%), Gaps = 51/464 (10%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLAT--ATTGPSKAKTSRTPSRD 185
PP P L + P P + P+ K T A T PS TPS
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 186 SQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKA----PSVKR 241
T + P+ GG P K + T TP S + + P K P+
Sbjct: 1216 GAPTTPAATPPS---PKGGLATPSPKGAPT-TPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 242 TPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDK 301
+ ATP AP A + P SP K A+ P S P P
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 302 VPTPEKMVTPEDK------ASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDK 355
PTP + P K A+ P + P + + P+ P S + PA+ PP K
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM-TPPSPK 1390
Query: 356 ----VPNPKMAPLGDEAPTL--EKVLTPELSEEEVST--RDDIQFHHFSSEEALQKVKYF 407
+P+PK P L +K ++ E +T + D+ + +
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 408 VAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEK 467
K P++ P P PPS + +P+Q S P PA
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKE------------PPAPKQVATSSSPKKAPATPA 1498
Query: 468 PHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKE 527
P A TLP PS+ + P A P+ + R+ + P + SK+ L PKE
Sbjct: 1499 P---MGAPTLPAVIPSSPKEVP---ATPSSR---RDPIAPTATLLSKK---TPATLAPKE 1546
Query: 528 EVAPKEEVPPIERAFAQKTRPIKPP--PDSQETLALPSLVPQNY 569
+ P P + P + P P S+E + P++ P Y
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
Score = 61.6 bits (148), Expect = 2e-09
Identities = 106/446 (23%), Positives = 149/446 (33%), Gaps = 63/446 (14%)
Query: 155 MPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSK 214
MP + P K AT A T+ + S K P G + + P K
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 215 TQTPQQRSVSSQEEEHSSP---VKAPSVKRTPMPDKTATPERP------PAPENAPSSKK 265
P + + ++ SP + PS K P ATP P P+P+ AP++
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLATPSPKGAPTTPA 1222
Query: 266 IPAPDK-----VPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASI--P 318
P PSP+ T A+ P P P PTP P K + P
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTT-PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 319 ENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDE---APTLEKVL 375
+ P + P +P+ + PP P+PK +P APT V
Sbjct: 1282 PHKGAPNPAVVT--PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
Query: 376 TPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEA-----PPPQPP 430
P K + PSS+ TP + PP P
Sbjct: 1340 PPS-----------------------PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
Query: 431 SSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPE 490
S + + RG + P + PA P K P T PS + TP
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPP 1436
Query: 491 EEAPPNEQRPLREEVLPKEGVA---SKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTR 547
P + ++ PK G A SK + TL PP +PKE PP + A +
Sbjct: 1437 AVTPVSLKKAPATSA-PKGGPATPSSKGDPTLPAVTPP----SPKE--PPAPKQVATSSS 1489
Query: 548 PIKPP--PDSQETLALPSLVPQNYTE 571
P K P P LP+++P + E
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKE 1515
Score = 54.7 bits (130), Expect = 3e-07
Identities = 107/473 (22%), Positives = 162/473 (34%), Gaps = 63/473 (13%)
Query: 126 VLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRD 185
V+P P K P V+RE A L P P K A AT+ P + + D
Sbjct: 1407 VIPLSP--KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464
Query: 186 SQKLTSRDSGPN---GGFQSGGSYHPGRKRSKTQTPQQRSV------SSQEEEHSSPVKA 236
P Q S P +K T P SS +E ++P
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSP-KKAPATPAPMGAPTLPAVIPSSPKEVPATP--- 1520
Query: 237 PSVKRTPM-PDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGK 295
S +R P+ P T ++ PA AP IP VPSP+KT + P +S +
Sbjct: 1521 -SSRRDPIAPTATLLSKKTPATL-APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578
Query: 296 IPAPDKV--------PTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPA 347
+P V P+P++++ P S P+E T + P S E+ PA
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELLIPP-----AVTSPSPKEAPTPPAVTPP----SPEKGPA 1629
Query: 348 LEAPPMDKVPNPKMAPLGDEAPTLEKVLT-------PELSEEEVSTRDDIQFHHFSSEEA 400
AP P ++PT +T P+ S+ + + A
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA 1689
Query: 401 LQKVKYFVAKEDPSSQEEAHTPEAPP--PQPPSSERCLGEMKCTLVRGDSSPRQAELKSG 458
+ A Q + + +PP P P + G + T+ P Q +
Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS-TVAPAPLLPVQKDSSKT 1748
Query: 459 PASRPALEKPH----PHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASK 514
+ A P P E + P A + ++ P+ E+ P LP +A
Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP---LAPS 1805
Query: 515 EEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQ 567
T LPPK++ P +E P KP + E LP + P+
Sbjct: 1806 PVPT----LPPKQQFLPSSPGLVLE-------SPSKPLAPADEDELLPLIPPE 1847
Score = 54.3 bits (129), Expect = 3e-07
Identities = 98/431 (22%), Positives = 137/431 (31%), Gaps = 43/431 (9%)
Query: 156 PKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKT 215
P+T P KK + P +S ++ L G S + H S
Sbjct: 803 PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
Query: 216 QTPQQRSVSSQEEEHSS-PVK---APSVKRTPMPDK---TATPERPPAPENAPSSKK--- 265
P +V+ + + P K PSV P P + T P++ PA SS K
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 266 -IPAPDKVP-SPEKTLTLGDKASIPGNSTSGKI-PAPDKVPTPEKMVTPEDKASIPENSI 322
PAP +P SP A+ P + G P+P PTP P K S
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 323 IPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEE 382
T P +P+ + PP P+PK +P P + TP +
Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP--KGASTPPAATP 1040
Query: 383 EVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCT 442
K P++ P P PPS + G
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK---GGPATP 1097
Query: 443 LVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDE---RTPEEEAPPNEQR 499
+G P A + P+ + L P PH+ A T P P + + TP + P
Sbjct: 1098 SPKGAPMPPAA---TPPSPKGGLATP-PHKGAPTTPAATPPSPKGGLATPPPKGAPT--T 1151
Query: 500 PLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERA-------FAQKTRPIKPP 552
P PK G+A+ PPK PP + T P P
Sbjct: 1152 PAATPPSPKGGLATP---------PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
Query: 553 PDSQETLALPS 563
P + LA PS
Sbjct: 1203 PSPKGGLATPS 1213
Score = 51.6 bits (122), Expect = 2e-06
Identities = 92/374 (24%), Positives = 131/374 (35%), Gaps = 57/374 (15%)
Query: 33 PPSLGNPDMPSVS-PGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDEL-- 89
P S G+P +P+V+ P P+ PP +A S P P L P +P E+
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518
Query: 90 --ALRRGDV---VKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPP------PIKKLVPR 138
+ RR + +LSK T + + P +P P P K P
Sbjct: 1519 TPSSRRDPIAPTATLLSKKT------PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Query: 139 KVVSRESAP-----------IKEPKKLM--PKTSLPTVKKLAT--ATTGPSKAKTSRTPS 183
S+E++ PK+L+ P + P+ K+ T A T PS K TP+
Sbjct: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632
Query: 184 RDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTP 243
TS P+ S S + PQ S P V P
Sbjct: 1633 PKGTP-TSPPVTPSSLKDSPTSPASVTCKMGATVPQ---ASKGLPAKKGPTALKEVLVAP 1688
Query: 244 MPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVP 303
P+ T P P +KK A P+ + G K + ST P
Sbjct: 1689 APESTPIITAP--TRKGPQTKKSSATSPPICPDPSAKNGSKGPL---STVAPAPLLPVQK 1743
Query: 304 TPEKMVTPEDKASIPENSIIPEETLTVDKPSTP------ERVFSVEESPALEAPPMDKVP 357
K +D + P+ + P E+ K STP E+V ES ++ A P V
Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPES----KASTPLTAAAFEKVLPKPESASVSAAPSPPVS 1799
Query: 358 NPKMAPLGDEAPTL 371
P +AP PTL
Sbjct: 1800 LP-LAP--SPVPTL 1810
Score = 49.7 bits (117), Expect = 8e-06
Identities = 108/479 (22%), Positives = 145/479 (30%), Gaps = 60/479 (12%)
Query: 128 PPPPIKKLVPRKVVSRES---APIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSR 184
P P K P ++ S A K +P + P A T PS TPS
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 185 DSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPM 244
+ P+ GG P K + T SP AP+
Sbjct: 960 KWAPTPPAATPPS---PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016
Query: 245 PDKTATPERPPAPENA--------PSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKI 296
P +P P P+ A PS K PA +P T A++P
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT---PAATLPSPKGGPAT 1073
Query: 297 PAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKV 356
P+ PTP P K S P +P+ + P
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133
Query: 357 PNPK---MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDP 413
P+PK P APT TP + ++T + A P
Sbjct: 1134 PSPKGGLATPPPKGAPT-TPAATPPSPKGGLATPPP---KGAPTTPAATPPSPKGGLATP 1189
Query: 414 SSQEEAHTPEAPPPQP------PSSERCLGEMKCTLVR---GDSSPRQAELKSGPASRPA 464
S + TP A PP P PS + T G ++P + PA+ P
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 465 LEKPHPHEEATTLPEEAPSNDERTPEE-----EAPPNEQRPLREEVL---PKEGVASKEE 516
K P AT P+ AP+ TP PP++ P V PK G A+
Sbjct: 1250 SPKGGP---ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-- 1304
Query: 517 VTLKEELPPKEEVAPKEEVPPIERAF-------AQKTRPIKPPPDSQETLALPSLVPQN 568
PPK P PP + T P PP + T LP+ P +
Sbjct: 1305 -------PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356
Score = 47.0 bits (110), Expect = 5e-05
Identities = 93/428 (21%), Positives = 123/428 (28%), Gaps = 39/428 (9%)
Query: 126 VLPPPP----IKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRT 181
V PP P P+ + +A PK T LP A T PS T
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 182 PSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSK---TQTPQQRSVSSQEEEHSSPVKAPS 238
PS + P+ GG P K + TP H P+
Sbjct: 1074 PSLKGAPTPPAATPPS---PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 239 VKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPA 298
ATP AP ++ P P K A+ P P+
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 299 PDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPN 358
P PT P K + S T P +P+ + P P+
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 359 PKMAPLGDE---APTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSS 415
PK P APT P L + H + A+ V K P++
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPP-----HKGAPNPAV--VTPPSPKGGPAT 1303
Query: 416 QEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEAT 475
P P PPS + G +P + PA P K P AT
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPG-----------TPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 476 TL-----PEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVA---SKEEVTLKEELPPKE 527
T P S + TP P ++ P PK G A K + T +P
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 528 EVAPKEEV 535
+ AP V
Sbjct: 1413 KKAPATPV 1420
Score = 39.7 bits (91), Expect = 0.009
Identities = 89/368 (24%), Positives = 122/368 (33%), Gaps = 92/368 (25%)
Query: 240 KRTPMPDKTAT--PERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKA--SIPGNST--S 293
K P+ + T T P P A EN P + P+P +P TL L + S+P S +
Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVA---PSPQNTCAPLATLVLAPEIPKSVPSPSLPPA 742
Query: 294 GKIPAPDKVP-------------TPEKMVTPEDKASIPENSIIPEETLT--VDKPSTPER 338
G P KV +P++ T + AS +S + TLT D PS
Sbjct: 743 GTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS---KGTLTYLADSPSP--- 796
Query: 339 VFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVS---TRDDIQFHHF 395
V SP + PP K P+G+ + + V L E +S ++D H
Sbjct: 797 -LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS 855
Query: 396 SSEEALQKVKYFVAKEDPSSQEEAHTPEA-----------PPPQPPSSERC--------- 435
+ P S + A TP A PP + P+
Sbjct: 856 PT---------------PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 436 ---LGEMKCTLVRGDSSPRQAELKSGPASRPALEKPH--PHEEATTLPEEAPSNDERTPE 490
+ L SSP++A P PA P P A T P +P TP
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP--SPKGGPATPS 958
Query: 491 EEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIK 550
+ P P PK G A+ PK P PP + K P
Sbjct: 959 PKWAPTP--PAATPPSPKGGPATPS---------PKGAPTPPAATPP-----SPKGGPAT 1002
Query: 551 PPPDSQET 558
P P T
Sbjct: 1003 PSPKGAPT 1010
Score = 31.2 bits (69), Expect = 3.1
Identities = 97/442 (21%), Positives = 147/442 (33%), Gaps = 104/442 (23%)
Query: 215 TQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVP- 273
TQ Q +S E SP +A T D T P AP+N+PS + + ++P
Sbjct: 528 TQKDLQTVPASLEGAPFSPAQAGL---TTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL 584
Query: 274 SPEKTL---TLGDKASIP----------GNSTSGKIPAPDKVPTPE--------KMVTP- 311
SPE TL +LG+ I G ++S + D P+ ++TP
Sbjct: 585 SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644
Query: 312 --------EDKASI--------------------------PENSIIPEETLTVDKPSTPE 337
D A + P+N + E TLT P P
Sbjct: 645 VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTT-LPLVPT 703
Query: 338 RVFSVEESPALE-----------APPMDK-VPNPKMAPLGDEAPTLE-------KVLTPE 378
+ +P+ + AP + K VP+P + P G T + L P
Sbjct: 704 ASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV 763
Query: 379 LSE-EEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSS--ERC 435
S +E T D SS+ L Y P + + PP + S+ +
Sbjct: 764 ASSPKECPTEDSGASATASSKGTL---TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
Query: 436 LGEMKCTL--VRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERT---PE 490
+G + + V P + G PA H P+ AP+ T P+
Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPAT----THSPTPPSPKGAPTPSAVTPLSPK 876
Query: 491 EEAPPNEQRPLREEV---LPKEGVAS-----KEEVTLKEELPPKEEVAPKEE-VPPIERA 541
P ++ P V PKEG A+ +++ P K P + +P
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936
Query: 542 FAQKTRPIKPPPDSQETLALPS 563
T P PP + A PS
Sbjct: 937 KGAPTPPAATPPSPKGGPATPS 958
Score = 31.2 bits (69), Expect = 3.1
Identities = 73/345 (21%), Positives = 116/345 (33%), Gaps = 48/345 (13%)
Query: 33 PPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALR 92
PP++ +P P +P P S + P T + P V P +P + +
Sbjct: 1602 PPAVTSPS-PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 93 RGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLVPRKVVSRESAPI---- 148
G V SK K + P++ + P +K K S S PI
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
Query: 149 ------KEPKKLMPKTSLPTVKKLATATT----------GP-----SKAKTSRTPSRDSQ 187
K P + L V+K ++ T GP SKA T T + +
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780
Query: 188 KLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSP---VKAPSVKRTPM 244
L +S S P +P Q+ SSP +++PS P
Sbjct: 1781 VLPKPESASVSAAPS-----PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 245 PDKTATPERPPAP-----------ENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTS 293
+ P PP P N P+ K P PS ++ +T +K S + +
Sbjct: 1836 DEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD 1895
Query: 294 GKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPER 338
+P ++ + + A+ E I EE ++ K S E+
Sbjct: 1896 ESVPELEEQDSTQATTQQAQLAAAAE---IDEEPVSKAKQSRSEK 1937
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 73.6 bits (179), Expect = 5e-13
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 29/129 (22%)
Query: 3 KEIEDGWWLGK-----KNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSL 57
K+ GWW G+ K Q+G FP+N+V+LL G + P PPK ++L
Sbjct: 1105 KKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKIT----------PTEPPKSTAL 1154
Query: 58 AYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGR 117
A Q + ++DY + DELA +G ++ VL+K ED WW+GE G+
Sbjct: 1155 AA-----VCQVIG-------MYDYTAQNDDELAFNKGQIINVLNK--EDPDWWKGEVNGQ 1200
Query: 118 RGVFPDNFV 126
G+FP N+V
Sbjct: 1201 VGLFPSNYV 1209
Score = 63.5 bits (153), Expect = 6e-10
Identities = 41/125 (32%), Positives = 62/125 (49%), Gaps = 11/125 (8%)
Query: 2 IKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDS 61
+ E +D WW G+ GQ G FP ++V+L+ SGP S+ G P +SL +
Sbjct: 942 VLEQQDMWWFGEVQGQKGWFPKSYVKLI-SGPIRKST----SMDSGSSESP--ASLKRVA 994
Query: 62 PPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVF 121
P VS E + ++ Y+ +L ++GDV+ V T +D WW G + GVF
Sbjct: 995 SPAAKPVVSGEE-FIAMYTYESSEQGDLTFQQGDVILV---TKKDGDWWTGTVGDKAGVF 1050
Query: 122 PDNFV 126
P N+V
Sbjct: 1051 PSNYV 1055
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 33/143 (23%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD 60
++ + + WW G + G FPSN+V L D S G K SL
Sbjct: 1030 LVTKKDGDWWTGTVGDKAGVFPSNYVRLKD--------------SEGSGTAGKTGSLG-- 1073
Query: 61 SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRR-- 118
PE+ +V+ Y P++L L G ++ + K GWWEGE Q R
Sbjct: 1074 ---------KKPEIAQVIASYTATGPEQLTLAPGQLILIRKK--NPGGWWEGELQARGKK 1122
Query: 119 ---GVFPDNFV-LPPPPIKKLVP 137
G FP N+V L P K+ P
Sbjct: 1123 RQIGWFPANYVKLLSPGTSKITP 1145
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
Query: 75 YRVLFDYQPEAPDELALRRGDVVKVLSK-----TTEDKGWWEGECQGRRGVFPDNFVLPP 129
YR L+ ++ + DE+ ++ GD+V V + T + GW GE +G+ G FP N+
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 130 PPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPS 174
P + P K V+ +S PK + +T P + +T P+
Sbjct: 805 PENEVPAPVKPVT-DSTSAPAPKLALRETPAPLAVTSSEPSTTPN 848
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV-LPPPPIKK 134
+ L+ ++ + + L + DV+ VL + WW GE QG++G FP ++V L PI
Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLE---QQDMWWFGEVQGQKGWFPKSYVKLISGPI-- 973
Query: 135 LVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLAT 168
RK S +S + P L + + P K + +
Sbjct: 974 ---RKSTSMDSGSSESPASL-KRVASPAAKPVVS 1003
Score = 38.9 bits (89), Expect = 0.015
Identities = 15/35 (42%), Positives = 23/35 (65%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPS 35
++ + + WW G+ NGQ+G FPSN+V+L PS
Sbjct: 1184 VLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPS 1218
Score = 30.4 bits (67), Expect = 5.3
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 28/125 (22%)
Query: 521 EELPPKEEVAPKEEVPPIERAFAQKT------------RPIKPPPDSQETLALPSLVPQN 568
+ LPP V P E +PP R + R + P E L +P
Sbjct: 293 QPLPP---VLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVT 349
Query: 569 YTENKNEGVDVTSLRGEVESLRRALELME---------VQLERKLTDIWEELKSEKEQRR 619
+ + K E + RG +E +R L+E QLER + E + E+E++R
Sbjct: 350 FEDKKRENFE----RGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKR 405
Query: 620 RLEVQ 624
+LE++
Sbjct: 406 QLELE 410
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 73.6 bits (179), Expect = 5e-13
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 29/129 (22%)
Query: 3 KEIEDGWWLGK-----KNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSL 57
K+ GWW G+ K Q+G FP+N+V+LL G + P PPK ++L
Sbjct: 1105 KKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKIT----------PTEPPKSTAL 1154
Query: 58 AYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGR 117
A Q + ++DY + DELA +G ++ VL+K ED WW+GE G+
Sbjct: 1155 AA-----VCQVIG-------MYDYTAQNDDELAFNKGQIINVLNK--EDPDWWKGEVNGQ 1200
Query: 118 RGVFPDNFV 126
G+FP N+V
Sbjct: 1201 VGLFPSNYV 1209
Score = 63.5 bits (153), Expect = 6e-10
Identities = 41/125 (32%), Positives = 62/125 (49%), Gaps = 11/125 (8%)
Query: 2 IKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDS 61
+ E +D WW G+ GQ G FP ++V+L+ SGP S+ G P +SL +
Sbjct: 942 VLEQQDMWWFGEVQGQKGWFPKSYVKLI-SGPIRKST----SMDSGSSESP--ASLKRVA 994
Query: 62 PPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVF 121
P VS E + ++ Y+ +L ++GDV+ V T +D WW G + GVF
Sbjct: 995 SPAAKPVVSGEE-FIAMYTYESSEQGDLTFQQGDVILV---TKKDGDWWTGTVGDKAGVF 1050
Query: 122 PDNFV 126
P N+V
Sbjct: 1051 PSNYV 1055
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 33/143 (23%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYD 60
++ + + WW G + G FPSN+V L D S G K SL
Sbjct: 1030 LVTKKDGDWWTGTVGDKAGVFPSNYVRLKD--------------SEGSGTAGKTGSLG-- 1073
Query: 61 SPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRR-- 118
PE+ +V+ Y P++L L G ++ + K GWWEGE Q R
Sbjct: 1074 ---------KKPEIAQVIASYTATGPEQLTLAPGQLILIRKK--NPGGWWEGELQARGKK 1122
Query: 119 ---GVFPDNFV-LPPPPIKKLVP 137
G FP N+V L P K+ P
Sbjct: 1123 RQIGWFPANYVKLLSPGTSKITP 1145
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
Query: 75 YRVLFDYQPEAPDELALRRGDVVKVLSK-----TTEDKGWWEGECQGRRGVFPDNFVLPP 129
YR L+ ++ + DE+ ++ GD+V V + T + GW GE +G+ G FP N+
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 130 PPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPS 174
P + P K V+ +S PK + +T P + +T P+
Sbjct: 805 PENEVPAPVKPVT-DSTSAPAPKLALRETPAPLAVTSSEPSTTPN 848
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV-LPPPPIKK 134
+ L+ ++ + + L + DV+ VL + WW GE QG++G FP ++V L PI
Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLE---QQDMWWFGEVQGQKGWFPKSYVKLISGPI-- 973
Query: 135 LVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLAT 168
RK S +S + P L + + P K + +
Sbjct: 974 ---RKSTSMDSGSSESPASL-KRVASPAAKPVVS 1003
Score = 38.9 bits (89), Expect = 0.015
Identities = 15/35 (42%), Positives = 23/35 (65%)
Query: 1 MIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPS 35
++ + + WW G+ NGQ+G FPSN+V+L PS
Sbjct: 1184 VLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPS 1218
Score = 30.4 bits (67), Expect = 5.3
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 28/125 (22%)
Query: 521 EELPPKEEVAPKEEVPPIERAFAQKT------------RPIKPPPDSQETLALPSLVPQN 568
+ LPP V P E +PP R + R + P E L +P
Sbjct: 293 QPLPP---VLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVT 349
Query: 569 YTENKNEGVDVTSLRGEVESLRRALELME---------VQLERKLTDIWEELKSEKEQRR 619
+ + K E + RG +E +R L+E QLER + E + E+E++R
Sbjct: 350 FEDKKRENFE----RGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKR 405
Query: 620 RLEVQ 624
+LE++
Sbjct: 406 QLELE 410
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 73.6 bits (179), Expect = 5e-13
Identities = 104/457 (22%), Positives = 175/457 (38%), Gaps = 80/457 (17%)
Query: 130 PPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKL 189
P I P + + + P ++P K ++ T K + + + T +
Sbjct: 619 PTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIP 678
Query: 190 TSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKA--PSVKRT-PMPD 246
T + S P + P K + ++ S E+ SP K P+ K T P
Sbjct: 679 TEKPSIP--------TEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEK 730
Query: 247 KTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPE 306
T +PE+P P P+ IP SPEK T +K +I +PE
Sbjct: 731 STISPEKPTTPTEKPT---IPTEKPTISPEKPTTPTEKPTI----------------SPE 771
Query: 307 KMVTPEDKASIP-ENSIIPEE--TLTVDKPSTPERVFSVE-ESPALEAPPMDK--VPNPK 360
K+ P +K +IP E IP E T++ ++P+TP ++ E P++ PM+K +P +
Sbjct: 772 KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI---PMEKPTLPTEE 828
Query: 361 MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH 420
+E + LT + + +ST + + K ++ E + E
Sbjct: 829 TTTSVEETTISTEKLTIPMEKPTIST----------EKPTIPTEKPTISPEKLTIPTEKL 878
Query: 421 TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPAL--EKPHPHEEATTLP 478
T P P E + K T+ P +P + EKP E T+P
Sbjct: 879 TIPTEKPTIPIEETTISTEKLTI---------------PTEKPTISPEKPTISTEKPTIP 923
Query: 479 EEAPSNDERTPEEEAPPNEQR----PLREEVLPKEGVASKEEVTLKEELP--PKEEVAPK 532
E P+ P EE + ++ + + P++ E+ T+ E P P E++
Sbjct: 924 TEKPT----IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
Query: 533 EEVP--PIERAF--AQKTRPIKPPPDSQETLALPSLV 565
E P P E+ +K ++PP S L +LV
Sbjct: 980 TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALV 1016
Score = 44.3 bits (103), Expect = 4e-04
Identities = 53/241 (21%), Positives = 98/241 (40%), Gaps = 23/241 (9%)
Query: 352 PMDKVPN-PKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEE-ALQKVKYFVA 409
P+ +P P ++P+ P+ LT + I+ ++E+ + K K +
Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIP 594
Query: 410 KEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPAL--EK 467
E P+ E T + P PS + + K T++ + +E + P+ +P + EK
Sbjct: 595 TEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILT-EKPTIPSEKPTIPSEKPTISTEK 653
Query: 468 PH-PHEEATTLPEEAPSNDERT---PEEEAPPNEQRPLREE---VLPKEGVASKEEVTLK 520
P P EE TT EE ++ E E+ + P E+ + E + +E + S E+ T+
Sbjct: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
Query: 521 EELPP-----------KEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNY 569
E P K ++P++ P E+ +P P P++ P+
Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKL 773
Query: 570 T 570
T
Sbjct: 774 T 774
Score = 33.5 bits (75), Expect = 0.62
Identities = 46/182 (25%), Positives = 69/182 (37%), Gaps = 31/182 (17%)
Query: 422 PEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEA 481
PE PP P SS G + T G + K S +EKP E T+P+E
Sbjct: 540 PELPPVSPVSST---GPSETT---GLTENPTISTKKPTVS---IEKPSVTTEKPTVPKEK 590
Query: 482 P---------SNDERTPEEEAP--PNEQRPLREE---VLPKEGVASKEEVTLKEELP--- 524
P S ++ T E P P+E+ + E +L ++ E+ T+ E P
Sbjct: 591 PTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650
Query: 525 -PKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLR 583
K V +E P E P+ P E ++P+ P TE ++ T +
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIP----TEKPSIPTEKPSIPTEKPTISMEETIIS 706
Query: 584 GE 585
E
Sbjct: 707 TE 708
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 73.6 bits (179), Expect = 5e-13
Identities = 104/457 (22%), Positives = 175/457 (38%), Gaps = 80/457 (17%)
Query: 130 PPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKL 189
P I P + + + P ++P K ++ T K + + + T +
Sbjct: 619 PTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIP 678
Query: 190 TSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKA--PSVKRT-PMPD 246
T + S P + P K + ++ S E+ SP K P+ K T P
Sbjct: 679 TEKPSIP--------TEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEK 730
Query: 247 KTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPE 306
T +PE+P P P+ IP SPEK T +K +I +PE
Sbjct: 731 STISPEKPTTPTEKPT---IPTEKPTISPEKPTTPTEKPTI----------------SPE 771
Query: 307 KMVTPEDKASIP-ENSIIPEE--TLTVDKPSTPERVFSVE-ESPALEAPPMDK--VPNPK 360
K+ P +K +IP E IP E T++ ++P+TP ++ E P++ PM+K +P +
Sbjct: 772 KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI---PMEKPTLPTEE 828
Query: 361 MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAH 420
+E + LT + + +ST + + K ++ E + E
Sbjct: 829 TTTSVEETTISTEKLTIPMEKPTIST----------EKPTIPTEKPTISPEKLTIPTEKL 878
Query: 421 TPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPAL--EKPHPHEEATTLP 478
T P P E + K T+ P +P + EKP E T+P
Sbjct: 879 TIPTEKPTIPIEETTISTEKLTI---------------PTEKPTISPEKPTISTEKPTIP 923
Query: 479 EEAPSNDERTPEEEAPPNEQR----PLREEVLPKEGVASKEEVTLKEELP--PKEEVAPK 532
E P+ P EE + ++ + + P++ E+ T+ E P P E++
Sbjct: 924 TEKPT----IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
Query: 533 EEVP--PIERAF--AQKTRPIKPPPDSQETLALPSLV 565
E P P E+ +K ++PP S L +LV
Sbjct: 980 TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALV 1016
Score = 44.3 bits (103), Expect = 4e-04
Identities = 53/241 (21%), Positives = 98/241 (40%), Gaps = 23/241 (9%)
Query: 352 PMDKVPN-PKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEE-ALQKVKYFVA 409
P+ +P P ++P+ P+ LT + I+ ++E+ + K K +
Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIP 594
Query: 410 KEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPAL--EK 467
E P+ E T + P PS + + K T++ + +E + P+ +P + EK
Sbjct: 595 TEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILT-EKPTIPSEKPTIPSEKPTISTEK 653
Query: 468 PH-PHEEATTLPEEAPSNDERT---PEEEAPPNEQRPLREE---VLPKEGVASKEEVTLK 520
P P EE TT EE ++ E E+ + P E+ + E + +E + S E+ T+
Sbjct: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
Query: 521 EELPP-----------KEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNY 569
E P K ++P++ P E+ +P P P++ P+
Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKL 773
Query: 570 T 570
T
Sbjct: 774 T 774
Score = 33.5 bits (75), Expect = 0.62
Identities = 46/182 (25%), Positives = 69/182 (37%), Gaps = 31/182 (17%)
Query: 422 PEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEA 481
PE PP P SS G + T G + K S +EKP E T+P+E
Sbjct: 540 PELPPVSPVSST---GPSETT---GLTENPTISTKKPTVS---IEKPSVTTEKPTVPKEK 590
Query: 482 P---------SNDERTPEEEAP--PNEQRPLREE---VLPKEGVASKEEVTLKEELP--- 524
P S ++ T E P P+E+ + E +L ++ E+ T+ E P
Sbjct: 591 PTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650
Query: 525 -PKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLR 583
K V +E P E P+ P E ++P+ P TE ++ T +
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIP----TEKPSIPTEKPSIPTEKPTISMEETIIS 706
Query: 584 GE 585
E
Sbjct: 707 TE 708
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 72.4 bits (176), Expect = 1e-12
Identities = 130/546 (23%), Positives = 186/546 (34%), Gaps = 108/546 (19%)
Query: 27 ELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVL--FDYQPE 84
E L + PP P+ +SP P+ P PP+ PE R+ F+ P
Sbjct: 559 EELPTSPP----PEASRLSPPPEESPM------SPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 85 AP--DELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLVPRKVVS 142
+P +E L LS ED ++ + PPP + +L P VVS
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPP--------EESPMSPPPEVSRLSPLPVVS 660
Query: 143 RESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQS 202
R S P +E P P T+ P +A P DS
Sbjct: 661 RLSPPPEESPLSPPPEESP--------TSPPPEASRLSPPPEDSPT-------------- 698
Query: 203 GGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPS----VKRTPMPDKTATPERP---P 255
P + S P + S+ S E S + P R+ P + PE P P
Sbjct: 699 ----SPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 256 APENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGN-STSGKIPAPDKVPTPEKM-VTPED 313
PE S + P P PE+ ++P S + P P PE++ ++P+
Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCL----CAVPEEPHLSPQAEGPHLSPQPEELHLSPQT 810
Query: 314 KASIPENSIIPEETLTVDKPSTPERVFSVEE------------SPALEAPPMDKVP---- 357
+ P S +PEE +P EE SP LE PP+ P
Sbjct: 811 EE--PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP 868
Query: 358 -NPKMAPLGDEAPTL----EKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKED 412
P P +E P E L+P L E +S + E L +
Sbjct: 869 EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS------PSGE 922
Query: 413 PSSQEEAHTPEAPPP--------QPPSSERCLGEMKCTL-VRGDSSPRQAELKSGPASRP 463
PS + P+ PP P + LGE++ +GDS P P + P
Sbjct: 923 PSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP------ESPLAAP 976
Query: 464 ALEKP--HPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKE 521
LE P P E T PE P P +P P+ E LP + + + +
Sbjct: 977 ILETPISPPPEANCTDPEPVPPM-ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQ 1035
Query: 522 ELPPKE 527
PP +
Sbjct: 1036 NSPPSQ 1041
Score = 48.5 bits (114), Expect = 2e-05
Identities = 79/341 (23%), Positives = 118/341 (34%), Gaps = 81/341 (23%)
Query: 234 VKAPSVKRTPM-PDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNST 292
++AP + P+ P +P PP PE +P+S A P PE
Sbjct: 430 LEAPLNEEMPLLPPPEESPLSPP-PEESPTSPPPEASRLSPPPE---------------- 472
Query: 293 SGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFS-VEESPALEAP 351
++PA P PE + P + E L+ S+P FS +EESP +P
Sbjct: 473 --ELPAS---PLPEALHLSRPLEESPLSPPPEESPLSPPPESSP---FSPLEESPL--SP 522
Query: 352 PMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKE 411
P + P +P LE L+P +S +E
Sbjct: 523 PEESPP----------SPALETPLSPPPEASPLSP---------------------PFEE 551
Query: 412 DPSSQEEAHTPEAPPPQ-----PPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALE 466
P S P +PPP+ PP E + S P + S P L
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPM-----------SPPPEESPMSPPPEASRLF 600
Query: 467 KPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEG-VASKEEVTLKEELPP 525
P + PEE+P + +PP E P+ P+E ++ EV+ LP
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP--PEESPMSPPPEVSRLSPLPV 658
Query: 526 KEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
++P E P+ + P PPP++ P P
Sbjct: 659 VSRLSPPPEESPLSP--PPEESPTSPPPEASRLSPPPEDSP 697
Score = 47.0 bits (110), Expect = 5e-05
Identities = 79/336 (23%), Positives = 120/336 (35%), Gaps = 22/336 (6%)
Query: 242 TPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDK 301
+P P+++ T P A +P +++PA + + L + P S P P+
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 302 ---VPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPN 358
P E ++P ++ S P ++ ET P EESP L PP + +
Sbjct: 510 SPFSPLEESPLSPPEE-SPPSPAL---ETPLSPPPEASPLSPPFEESP-LSPPPEELPTS 564
Query: 359 PKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQ--FHHFSSEEALQKVKYFVAKEDPSSQ 416
P P E ++P E +S + F F + P +
Sbjct: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624
Query: 417 EEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATT 476
+ PE P PP E + + R P + L P P P P E T+
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPP-EVSRLSPLPVVSRLSPPPEESPL--SPPPEESPTS 681
Query: 477 LPEEAPSNDERTPEEE--APPNEQRPLREEVLPKEGVAS--KEEVTLKEELPPKEEVAPK 532
P EA S PE+ +PP E P P++ + S EE L LP + ++ P+
Sbjct: 682 PPPEA-SRLSPPPEDSPTSPPPEDSPASPP--PEDSLMSLPLEESPLL-PLPEEPQLCPR 737
Query: 533 EEVPPIE-RAFAQKTRPIKPPPDSQETLALPSLVPQ 567
E P + R P P P L PQ
Sbjct: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773
Score = 45.4 bits (106), Expect = 2e-04
Identities = 70/288 (24%), Positives = 100/288 (34%), Gaps = 42/288 (14%)
Query: 297 PAPDKVPTPEKMVTPEDKASIPEN----SIIPEETLTVDKPSTPERVFSVEESPALEAP- 351
P P PT E P+ S+ P+E + + P V+ P LEAP
Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPL 434
Query: 352 --PMDKVPNPKMAPLG---DEAPTLEKVLTPELSE--EEVSTRDDIQFHHFSSEEALQKV 404
M +P P+ +PL +E+PT LS EE+ + H S
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP------ 488
Query: 405 KYFVAKEDPSSQEEAHTPEAPPPQP----PSSERCLGEMKCTLVRGDSSPRQAELKSGPA 460
+E P S +P +PPP+ P E L + SP S P
Sbjct: 489 ----LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE----ESPPSPALETPLSPPP 540
Query: 461 SRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLK 520
L P + PEE P++ +PP E+ P+ P E
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP---PPEESPMSPPPEAS 597
Query: 521 EELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQN 568
PP EE +P PP E + P+ PPP++ P P +
Sbjct: 598 RLFPPFEE-SPLS--PPPEES------PLSPPPEASRLSPPPEDSPMS 636
Score = 42.4 bits (98), Expect = 0.001
Identities = 84/398 (21%), Positives = 146/398 (36%), Gaps = 56/398 (14%)
Query: 174 SKAKTSRTPSRDSQKLTSRDSG----PNGGFQSGGSYHPGRKRS-KTQTPQQRSVSSQEE 228
++++T +P + Q+ + G P F S G+ P + K Q +VSS+
Sbjct: 3979 NQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEAT 4038
Query: 229 EHSSPVKAPSVKRTPMPDKTATPE---RP------------PAPENAPSSKKIPAPDKVP 273
E S + + P+ AT +P P P+ PSS ++ P ++P
Sbjct: 4039 EGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLP 4098
Query: 274 SPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKP 333
++ G + G++ + + +S+P P +L D+P
Sbjct: 4099 GQQQQQV--SLLHTAGGGSHGQLGSGSS----------SEASSVPHLLAQPSVSLG-DQP 4145
Query: 334 STPERVFSVEESPALEAPPMDKV--PNPKMAPLGDEAPTLEKV-LTPELSEEEVSTRDDI 390
+ + + P LE P + PK P+ L V + P + + + +
Sbjct: 4146 GSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVL 4205
Query: 391 ----QFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRG 446
Q H S ++ Q + ++ SQ TP P +S G + C G
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP-LQGLLGCQPQLG 4264
Query: 447 -----DSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPL 501
+ P Q EL +GP + P P +T P P + TP +P Q P
Sbjct: 4265 GFPGPQTGPLQ-ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP--TPPPSSP---QEPK 4318
Query: 502 REEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIE 539
R LP + ++ + +LPP PK + P +E
Sbjct: 4319 RPSQLP----SPSSQLPTEAQLPPTHPGTPKPQGPTLE 4352
Score = 33.5 bits (75), Expect = 0.62
Identities = 61/257 (23%), Positives = 93/257 (36%), Gaps = 42/257 (16%)
Query: 250 TPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMV 309
TP P+ + + P+ D + PE G KAS P + P + + +
Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEP------LLSPPPFGESRKALE 2286
Query: 310 TPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVP-NPKMAPLGDEA 368
+++ S P VD PS+ + +E L+ P + K P P+ + + ++
Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE----LKTPDVFKAPLTPRASQVEPQS 2342
Query: 369 PTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQ 428
P L L +E + S + + Y DP +Q P P PQ
Sbjct: 2343 PGLG------LRPQEPPPAQALAPSPPSHPDIFRPGSY----TDPYAQP----PLTPRPQ 2388
Query: 429 PPSSERCLGEMKCTLVRGDSSPRQAELKSGPASR-PALEKPHPHEEATTLPE----EAPS 483
PP E C C L PR L S P SR PA + ++ P EA
Sbjct: 2389 PPPPESC-----CAL-----PPR--SLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC 2436
Query: 484 NDERTPEEEAPPNEQRP 500
TP ++P RP
Sbjct: 2437 PSPVTPRFQSPDPYSRP 2453
Score = 31.2 bits (69), Expect = 3.1
Identities = 42/160 (26%), Positives = 64/160 (40%), Gaps = 20/160 (12%)
Query: 442 TLVRGDSSPRQAELKS----GPASRPALEK--------PHPHEEATTLPEEAPSND-ERT 488
T +GD P A+ +S G A P E P E+ T E S+D +R
Sbjct: 1819 TSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRI 1878
Query: 489 PEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRP 548
EE P E + L++ L K+ + S+ E L P E P++R F Q P
Sbjct: 1879 STEELPKMESKDLQQ--LFKDVLGSEREQHLGCGTPGLEGSRT-----PLQRPFLQGGLP 1931
Query: 549 IKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVES 588
+ P S + P L + +++ G + GE +S
Sbjct: 1932 LGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDS 1971
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 72.0 bits (175), Expect = 2e-12
Identities = 97/386 (25%), Positives = 143/386 (37%), Gaps = 63/386 (16%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 127
+ L+D E+PDEL+ R+GD++ VL + T+ GWW GR+G+ P N +
Sbjct: 9 KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYD 68
Query: 128 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180
P PP P+ + + P + ++P T P P
Sbjct: 69 KKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
Query: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240
TPS+ Q L + GP+ FQS P K++ T S Q H P A +
Sbjct: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTST-------FSKQTPHHPFPSPATDLY 165
Query: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 300
+ P + P +A I +VP D S G K+ P
Sbjct: 166 QVPPGPGGPAQDIYQVPPSAGMGHDI---YQVPPSM------DTRSWEGTKPPAKVVVPT 216
Query: 301 KVP---TPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMD-KV 356
+V E +D+ IP + + P D P + S + PPM K
Sbjct: 217 RVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG 276
Query: 357 PNPK--MAPLGDEAPTLEKVLTPE----LSEEEVSTRDDIQFHHFSSEEALQKVKYFVAK 410
PN + + + D P++EK L P + + S D+ EE F AK
Sbjct: 277 PNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAF-AK 335
Query: 411 EDPSSQEEAHTP---EAPPPQPPSSE 433
P + A TP APPP P +E
Sbjct: 336 AKPF--DPARTPLVLAAPPPDSPPAE 359
Score = 33.9 bits (76), Expect = 0.48
Identities = 90/405 (22%), Positives = 137/405 (33%), Gaps = 74/405 (18%)
Query: 7 DGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLS----SLAYDSP 62
DGWWL +G+ G P N +++L +G D PGP P + L +P
Sbjct: 41 DGWWLCSLHGRQGIVPGNRLKIL------VGMYDKKPAGPGPGPPATPAQPQPGLHAPAP 94
Query: 63 PDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFP 122
P T P YQP+ PD + L V + + +G ++
Sbjct: 95 PASQYTPMLPNT------YQPQ-PDSVYL-------VPTPSKAQQGLYQ----------- 129
Query: 123 DNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTP 182
V P P + P K S S P T L ++ GP++ P
Sbjct: 130 ---VPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDL---YQVPPGPGGPAQDIYQVPP 183
Query: 183 SRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQ---QRSVSSQEEEHSSP--VKAP 237
S + G+ P + T+ Q + +++E+ P + AP
Sbjct: 184 SAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAP 243
Query: 238 SVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIP 297
P P R P P V P L + +P + G P
Sbjct: 244 G----PQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPP 299
Query: 298 APDKVPTPEKMVTPEDKASIPENSIIPEETLTVD------KPSTPERVFSVEESPALEAP 351
+ V P +P+ ++ EET V KP P R V +P ++P
Sbjct: 300 SNHHAVYD---VPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSP 356
Query: 352 PMDKVPN-PKMAP-LGDEAPTL-------------EKVLTPELSE 381
P + V + P AP L D P L E+VL PE+++
Sbjct: 357 PAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVAD 401
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 70.1 bits (170), Expect = 6e-12
Identities = 123/542 (22%), Positives = 178/542 (32%), Gaps = 101/542 (18%)
Query: 31 SGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEA-PDEL 89
S PPSL P +P Q PP +++ +PP LQT+ +V L +A P L
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS-LQTIPPIQVPHSLTSPSLQAPPSPL 407
Query: 90 ALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLVPRKVVSRESAPIK 149
AL L T + + PR+ + ++P +
Sbjct: 408 ALSSLQATTSLGSPT---------------------LQATHSFLTMSPRQTQASLTSPSR 446
Query: 150 EPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPG 209
P S P L+ + P + S S S LT P S S+ P
Sbjct: 447 PAS--TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH---PLQALSSLASHSP- 500
Query: 210 RKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAP 269
+AP P +T + PP+ + P+S P
Sbjct: 501 -------------------------QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
Query: 270 DKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLT 329
+ +PS A P + S + P + TP A P + P LT
Sbjct: 536 ENLPS---------LAPPPLQTASAPLTTP-------HLETPPCPAPCPLQA--PPSPLT 577
Query: 330 VDKPSTPERVFS--VEESPALEAPPMDKVPNPKMAPLGDEAPTLEK--VLTPELSEEEVS 385
P TP + + + PAL +PP+ +P+P ++PL P L P +
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637
Query: 386 TRDDIQFHHFSSEEA--LQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTL 443
+ S +A V A P P +PP PP S
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-------- 689
Query: 444 VRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPN-EQRPLR 502
+ P QA P+L P P + + P P + TP +APP PL+
Sbjct: 690 ----TPPSQAP--------PSLAAP-PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 503 EEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALP 562
P T +PP AP +VPP A + KPPP + LA P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPL-LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
Query: 563 SL 564
L
Sbjct: 796 PL 797
Score = 66.2 bits (160), Expect = 9e-11
Identities = 102/420 (24%), Positives = 148/420 (35%), Gaps = 58/420 (13%)
Query: 170 TTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEE 229
T GP K+ +S + ++ + P+ G GG Q P RS+SS
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAG---GG----------LQRPASRSLSSSATP 248
Query: 230 HSSPVKA-PSVKRTPMPDKTATPERPPAPENAPSSKKIPA--PDKVPSPEKTLT--LGDK 284
SSP ++ PS + TP R PA + P K + A P +V P K LG
Sbjct: 249 LSSPARSGPSARGTP---------RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 285 ASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEE 344
+S P + S VP P+ TP P + L PS P + ++
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 345 SPAL---EAPPMDKVPNPKMAPLGDEAPTLE---KVLTPEL-SEEEVSTRDDIQFHHFSS 397
PA +APP P + P P ++ + +P L + +Q
Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
Query: 398 EEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKS 457
LQ F+ +Q +P P PP S ++ L S P Q L
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP----PLQAPLSLPASPPLQTSL-- 473
Query: 458 GPASRPALEKP---HPHEEATTLPEEAPS--------NDERTPEEEAPPNEQRPLREEVL 506
PA P L P HP + ++L +P T APP+ Q P
Sbjct: 474 SPAVSP-LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 507 PK-EGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRP---IKPPPDSQETLALP 562
P E + S L+ P P E PP + P PPP++ ++A P
Sbjct: 533 PPLENLPSLAPPPLQTASAPL--TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Score = 43.9 bits (102), Expect = 5e-04
Identities = 85/365 (23%), Positives = 124/365 (33%), Gaps = 69/365 (18%)
Query: 33 PPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALR 92
PP L P +P + PP + +PP L T PE + P+AP LA
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL-TTPPPETPSSIATPPPQAPPALA-- 599
Query: 93 RGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLV---PRKVVSRESAPIK 149
QG LP PP+ L P+ P++
Sbjct: 600 ------------------SPPLQG----------LPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 150 EPKKLMPKTSLPTVKKLATATTGPS-------KAKTSRTPSRDSQKLTSRDSGPNGGFQS 202
P P S P + P+ +A S PS Q S + P S
Sbjct: 632 APPS--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP---VS 686
Query: 203 GGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPM-PDKTATP--ERPPAPE- 258
+ P + P + S +SP +PS P P A P + PP+P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPP---ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 259 NAPSSKKIPAPDKVP----SPEKTLTLGDKASIPGNSTSGKIP-APDKVPTPEKMVTPED 313
+ P S P +VP +P + AS+P + + P AP + TP P
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 314 KASIPENS-IIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLE 372
AS P + P +L + +TP +APP+ P ++ P +PTL+
Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPP----------QAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 373 KVLTP 377
P
Sbjct: 854 APRRP 858
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 67.8 bits (164), Expect = 3e-11
Identities = 111/441 (25%), Positives = 159/441 (36%), Gaps = 84/441 (19%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATA-TTGPSK-AKTSRTPSRD 185
PPPP ++ + R A P L PK +L TTG S+ A + P
Sbjct: 497 PPPPPRRT--HSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNP 554
Query: 186 SQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVK-------APS 238
+ G GGS P R +T +P SSQ + P K +P
Sbjct: 555 ANSWVP-------GLSPGGSRRPPRSPERTLSPSS-GYSSQSGTPTLPPKGLAGPPASPG 606
Query: 239 VKRTPMPDKTATPERPPAPENAP-----SSKKIPAPDKVPSPEKTLTLGDKASIPGNSTS 293
+ P P++ + P A ++ SS PAP P+ LGD+ IP +
Sbjct: 607 KAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP-- 664
Query: 294 GKIPAPDKVPTPEKMVTPEDKA-SIPENSIIPEETLTVD----KPSTPERVFSVEESPAL 348
K+PAP P P K +P A ++ +++P T D P TP+ + P
Sbjct: 665 -KVPAPFS-PPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT----PLQ 718
Query: 349 EAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFV 408
E+P + K +P +P P PE+ E S + ++EE LQ
Sbjct: 719 ESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE-------TAEEPLQD----- 766
Query: 409 AKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKS-------GPAS 461
P PPP PP+ E + L D P + S GP+
Sbjct: 767 -------------PNWPPPPPPAPE------EQDLSMADFPPPEEAFFSVASPEPAGPSG 807
Query: 462 RPAL--EKPHPHEEATTLPEEAPSNDERTPEEEAP-PNEQRPLREEVLPKEGVASKEEV- 517
P L AT L + P + + P AP P P LP+ KE V
Sbjct: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQ-----KEPVG 862
Query: 518 TLKEELPPKEEVAPKEEVPPI 538
K PP+E+V P +
Sbjct: 863 CSKGGGPPREDVGAPLVTPSL 883
Score = 58.9 bits (141), Expect = 1e-08
Identities = 132/541 (24%), Positives = 190/541 (35%), Gaps = 78/541 (14%)
Query: 33 PPSLGNPDMPSVSPG-PQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLF--------DYQP 83
PP+ N +P +SPG +RPP+ Y P + QP
Sbjct: 551 PPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP 610
Query: 84 EAPDELALRRGDVVKVLSKTT----EDKGWWEGECQGRRGVFP--DNFVLPPPPIKKLVP 137
P+ + R V S T + G + + P D FV+PP P VP
Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP---KVP 667
Query: 138 RKVVSRESAPIKEPKKLMPKTSLPTVKKLATATT-----GPSKAKTSRTPSRDSQKLTSR 192
S P + P P + P V +TT P +T+ TP ++S ++
Sbjct: 668 APFSPPPSKP-RSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726
Query: 193 DSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRT---PMPDKTA 249
S P SYHP +K + V+APS T P+ D
Sbjct: 727 QSPPP---SPPPSYHPPPPPTK--------------KPEVVVEAPSASETAEEPLQDPNW 769
Query: 250 TPERPPAPENAP-SSKKIPAPDK----VPSPEKTLTLG------DKASIPGNSTSGKIPA 298
P PPAPE S P P++ V SPE G A+ ++T+ +I
Sbjct: 770 PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQP 829
Query: 299 PDKVPTPEKMVTPEDKASIPEN--SIIPEETLTVDKPSTPER--VFSVEESPA-LEAPPM 353
P P P +S P + + +E + K P R V + +P+ L+ +
Sbjct: 830 PGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRL 889
Query: 354 DKVPNPKMAP---LGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAK 410
V P AP LG AP +K L LS H + K A
Sbjct: 890 RSVGAPGGAPTPALGPSAP--QKPLRRALSGRASPVPAPSSGLHAA---VRLKACSLAAS 944
Query: 411 EDPSSQEEAHTPEAP--PPQPPSSERCL----GEMKCTLVRGDSSPRQAELKSG-PASRP 463
E SS + PEA PPQ P+S G K L R S QA+L+ A
Sbjct: 945 EGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELR 1004
Query: 464 ALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVL---PKEGVASKEEVTLK 520
++ + P + P+ P + PP R E L P G+ ++ T +
Sbjct: 1005 SISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKR 1064
Query: 521 E 521
E
Sbjct: 1065 E 1065
>gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Homo
sapiens]
Length = 847
Score = 66.2 bits (160), Expect = 9e-11
Identities = 32/64 (50%), Positives = 43/64 (67%), Gaps = 7/64 (10%)
Query: 74 VYRVLFDYQPEAPDELALRRGDVVKVLSK---TTEDKGWWEGECQGRRGVFPDNFVL--- 127
V+ LFDY+P DELALR+GD V+VLS+ + D+GWW G+ G+ G+FP N+V
Sbjct: 45 VWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGG 104
Query: 128 -PPP 130
PPP
Sbjct: 105 GPPP 108
Score = 38.5 bits (88), Expect = 0.019
Identities = 15/29 (51%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Query: 6 EDGWWLGKKNGQLGAFPSNFVELLDSGPP 34
++GWW G+ GQ+G FPSN+V GPP
Sbjct: 80 DEGWWAGQVGGQVGIFPSNYVS-RGGGPP 107
Score = 33.1 bits (74), Expect = 0.81
Identities = 39/150 (26%), Positives = 52/150 (34%), Gaps = 31/150 (20%)
Query: 204 GSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSS 263
G GR+RS+ + + + SSP+ +PS TP A PP P P
Sbjct: 574 GEAQNGRRRSR----MDEATWYLDSDDSSPLGSPS---TP----PALNGNPPRPSLEPEE 622
Query: 264 KKIPAPDKVPSPEKT-----------------LTLGDKASIPGNSTSGKIPAPDKVPTPE 306
K P P + S T L LG PG + +P PTP
Sbjct: 623 PKRPVPAERGSSSGTPKLIQRALLRGTALLASLGLGRDLQPPGGPGRERGESPTTPPTPT 682
Query: 307 KMVTPEDKASIPENSIIPEETLTVDKPSTP 336
P + P + +I T D P TP
Sbjct: 683 PAPCPTEP---PPSPLICFSLKTPDSPPTP 709
Score = 29.6 bits (65), Expect = 9.0
Identities = 30/136 (22%), Positives = 43/136 (31%), Gaps = 30/136 (22%)
Query: 233 PVKAPSVKRTPMPDKTATPERPPAPENAPSSK----KIPAPDKVPSPEKTLTLGDKASIP 288
P P +R P TP P P P S + PD P+P L IP
Sbjct: 663 PPGGPGRERGESPTTPPTPTPAPCPTEPPPSPLICFSLKTPDSPPTPAPLLL---DLGIP 719
Query: 289 GNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPAL 348
S K P ++ P ++ P + P TP
Sbjct: 720 VGQRSAKSPRREEEPR--------------GGTVSPPPGTSRSAPGTP---------GTP 756
Query: 349 EAPPMDKVPNPKMAPL 364
+PP+ + P+ +PL
Sbjct: 757 RSPPLGLISRPRPSPL 772
>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
Length = 1036
Score = 65.9 bits (159), Expect = 1e-10
Identities = 33/78 (42%), Positives = 48/78 (61%), Gaps = 5/78 (6%)
Query: 74 VYRVLFDYQPEAPDELALRRGDVVKVLSK---TTEDKGWWEGECQGRRGVFPDNFVLPPP 130
++ L+DY+ DEL+LRRG +V+VLS+ + D+GWW G+ Q R G+FP N+V P
Sbjct: 42 LWAALYDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAGQVQRRLGIFPANYVAPCR 101
Query: 131 PIKKLVPRKVVSRESAPI 148
P P SR S+P+
Sbjct: 102 PAAS--PAPPPSRPSSPV 117
Score = 35.0 bits (79), Expect = 0.21
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 13/51 (25%)
Query: 6 EDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSS 56
++GWW G+ +LG FP+N+V P P+ SP P PP S
Sbjct: 77 DEGWWAGQVQRRLGIFPANYVA-----------PCRPAASPAP--PPSRPS 114
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 65.5 bits (158), Expect = 1e-10
Identities = 98/405 (24%), Positives = 137/405 (33%), Gaps = 54/405 (13%)
Query: 170 TTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEE 229
T GP K+ +S + ++ + P+ G GG Q P RS+SS
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAG---GG----------LQRPASRSLSSSATP 239
Query: 230 HSSPVKA-PSVKRTPMPDKTATPERPPAPENAPSSKKIPA--PDKVPSPEKTLT--LGDK 284
SSP ++ PS + TP R PA + P K + A P +V P K LG
Sbjct: 240 LSSPARSGPSARGTP---------RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 290
Query: 285 ASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSI--IPEETLTVDKPSTPERVFSV 342
+S P + S P P P P A+ P + + TL P S
Sbjct: 291 SSSPLATPSPSAPPSPSAP-PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 343 EESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQ 402
+P +APP +P + P +P L + TP + AL
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP----------------QAPNAL- 392
Query: 403 KVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASR 462
V A P P +PP PP S + ++P S PAS
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLAAPPLQVPPSPPASP 450
Query: 463 PALEKPHPHEEATTLPEEAPSNDERTPEEEAPPN-EQRPLREEVLPKEGVASKEEVTLKE 521
P P +A P AP P +APP PL+ P + +
Sbjct: 451 PMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 522 ELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVP 566
LP P + PP+ A + P P + TL P P
Sbjct: 510 SLPMSPLATPPPQAPPV---LAAPLLQVPPSPPASPTLQAPRRPP 551
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 64.7 bits (156), Expect = 3e-10
Identities = 92/462 (19%), Positives = 163/462 (35%), Gaps = 72/462 (15%)
Query: 142 SRESAPIKEPKKLMPKTSLPTVK-KLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGF 200
SR +P E K+ P+ P+VK K + S + + P + ++ P
Sbjct: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIP-EPKEPSPEKNS 265
Query: 201 QSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENA 260
+ R RS++++ + S+ H+ P + R ++ +P R P+P
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR-----RHRSRSRSYSPRRRPSPRRR 320
Query: 261 PSSKKIPAPDKVPSPEK--------TLTLGDKASIPG---NSTSGKIPAPDKVPTPEKMV 309
PS ++ P ++P P + AS+ G +S+S + +P K P
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
Query: 310 TPEDKASIPENSIIPEETLTVDKPSTP---------------ERVFSVEESPALEAPPMD 354
P + ++ P P+TP R V SP + +
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
Query: 355 KVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPS 414
K + AP KV ELSE E + + ++ +++Q+ + + + S
Sbjct: 441 KHKGTEKRESPSPAPKPRKV---ELSESE-----EDKGGKMAAADSVQQRRQYRRQNQQS 492
Query: 415 SQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEA 474
S + + + +P S GE+ G + P+ R ++ P
Sbjct: 493 SSDSGSSSSSEDERPKRSHVKNGEV------GRRRRHSPSRSASPSPRKRQKETSPRGRR 546
Query: 475 TTLPEEAPSNDERTPEEEAPPNEQR-----PLREEVLPKEGVASKEEVTLKEELPPKEEV 529
P P+ R+P PP +R P R P P +
Sbjct: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP---------------PRRRSP 591
Query: 530 APKEEVPPIERAFA----QKTRPIKPPPDSQETLALPSLVPQ 567
+P+ PPI+R ++ K R PPP + A PS P+
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR-ASPSPPPK 632
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/361 (21%), Positives = 125/361 (34%), Gaps = 57/361 (15%)
Query: 210 RKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAP 269
++ K + +Q ++S +++ K ++ +K ER +P S + P+P
Sbjct: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKR---ERSRSPRRRKS--RSPSP 182
Query: 270 DKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLT 329
+ SP + + P + T + P+P PE K PE +PE ++
Sbjct: 183 RRRSSPVRRERKRSHSRSPRHRTKSRSPSP----------APEKKEKTPE---LPEPSVK 229
Query: 330 VDKPSTPERVFSVEESPALEAPPMDKVPNPK-MAPLGDEAPTLEKVLT----PELSEEEV 384
V +PS E + S L+ P + +P PK +P + EK T S+
Sbjct: 230 VKEPSVQE---ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
Query: 385 STRDDIQFHHFSSEEALQKVKYFVAKEDPSSQE----EAHTPEAPPPQPPSSERCLGEMK 440
TR H + + + + PS + TP P PP R ++
Sbjct: 287 RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVR 346
Query: 441 ------CTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAP 494
+L SS + +S P P P + P +P P A
Sbjct: 347 RRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406
Query: 495 P-------------NEQRPLREEVLP--KEGVASKEEVTLKEELPP------KEEVAPKE 533
P N R R V P G +K + T K E P K E++ E
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466
Query: 534 E 534
E
Sbjct: 467 E 467
Score = 50.8 bits (120), Expect = 4e-06
Identities = 102/467 (21%), Positives = 159/467 (34%), Gaps = 78/467 (16%)
Query: 137 PRKVVSRESAPIKEPKKLMPKTSLPTVK-KLATATTGPSKAKTSRTPSRDSQKLTSRDSG 195
P+K R S+P ++ ++L P S P + + + T P K + S TP + ++ SR S
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430
Query: 196 PNGGFQSGGSYHPG--RKRSKTQTPQQRSV---SSQEEEHSSPVKAPSVKRTPM------ 244
G + H G ++ S + P+ R V S+E++ A SV++
Sbjct: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490
Query: 245 -------PDKTATPERPPAP-----------ENAPSSKKIPAPDKVPSPEKTLTLGDKAS 286
++ ERP ++PS P+P K ++T G +
Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK--RQKETSPRGRRRR 548
Query: 287 IPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESP 346
P + + +P P P + TP P T PS P R S SP
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTP----------PPRRRT---PSPPPRRRS--PSP 593
Query: 347 ALEAPPMDK----VPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQ 402
+PP+ + P PK P + + VS + SS +
Sbjct: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK--QRSSPVTKR 651
Query: 403 KVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASR 462
+ +K S T EA PQP + P + S P R
Sbjct: 652 RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRR 711
Query: 463 PALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEE 522
+ P P +T P S RTPE + P + V V+S V+ E
Sbjct: 712 ---QSPSP----STRPIRRVS---RTPEPKKIKKAASPSPQSV---RRVSSSRSVSGSPE 758
Query: 523 LPPKEEVAPKEEVP------------PIERAFAQKTRPIKPPPDSQE 557
K+ AP V P+++A + P P QE
Sbjct: 759 PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQE 805
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/247 (23%), Positives = 97/247 (39%), Gaps = 31/247 (12%)
Query: 129 PPPIKKLVPRKVVSRES-APIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
PPP ++ P R + +P + P+ P +++ + + P + S P
Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP---- 620
Query: 188 KLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRS--VSSQEEEHSSPVKAPSVKRTPMP 245
R + P+ + S+ P K+ + ++RS +SS+ + SSP ++ R+P P
Sbjct: 621 --PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQP 678
Query: 246 DKTATPE-RPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPT 304
+K +P RP AP+ + S P P + +S P S P+P P
Sbjct: 679 NKRHSPSPRPRAPQTSSS----------PPPVRR----GASSSPQRRQS---PSPSTRPI 721
Query: 305 PEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPL 364
TPE K S P+ V + R S PA + PP P +P
Sbjct: 722 RRVSRTPEPKKIKKAASPSPQSVRRV----SSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
Query: 365 GDEAPTL 371
+ +P +
Sbjct: 778 TNWSPAV 784
Score = 44.3 bits (103), Expect = 4e-04
Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 27/191 (14%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQ 187
PPPP ++ P R + PK + S P K+ + + + SK + +PSR ++
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPK----QRSSPVTKRRSPSLS--SKHRKGSSPSRSTR 671
Query: 188 KLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQR---SVSSQEEEHSSPVKAP--SVKRT 242
+ S P + S P ++ + P R S S Q + SP P V RT
Sbjct: 672 EARS----PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT 727
Query: 243 PMPD--KTATPERPPAPENAPSSKKI-----PAPDKVPSPEKTLTLGDKASIPGNSTSGK 295
P P K A P + SS+ + PA K P+P + ++ P + S
Sbjct: 728 PEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV----QSQSPSTNWSPA 783
Query: 296 IPAPD-KVPTP 305
+P K PTP
Sbjct: 784 VPVKKAKSPTP 794
Score = 41.6 bits (96), Expect = 0.002
Identities = 100/473 (21%), Positives = 167/473 (35%), Gaps = 72/473 (15%)
Query: 129 PPPIKKLVPRKVVSRESAPIKEPK-----KLMPKTSLPTVKKLATATTGPSKAKTSRTPS 183
P P K PRKV ES K K + + + +++ +G S + P
Sbjct: 451 PSPAPK--PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508
Query: 184 RDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKR-T 242
R K NG + P R S + +Q+ S + SP P+ +R +
Sbjct: 509 RSHVK--------NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
Query: 243 PMPDKTATPERPPAPENAPSSKKIPAPD---KVPSPEK---TLTLGDKASIPGNSTSGKI 296
P P R P P P ++ P+P + PSP + + S P +
Sbjct: 561 PSPAPPPRRRRTPTP---PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617
Query: 297 PAPDK-----VPTPEKMVT----PEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPA 347
P P K P P++ V+ P+ ++S P + K S+P R SP
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP- 676
Query: 348 LEAPPMDKVPNPK-MAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKY 406
P P+P+ AP +P P + S+ Q S + + ++
Sbjct: 677 --QPNKRHSPSPRPRAPQTSSSP-------PPVRRGASSSPQRRQ----SPSPSTRPIRR 723
Query: 407 FVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALE 466
+P ++A +P PQ VR SS R PA++
Sbjct: 724 VSRTPEPKKIKKA---ASPSPQS--------------VRRVSSSRSVSGSPEPAAKKPPA 766
Query: 467 KPHPHEEATTLPEEAPSNDERTPEEEAP-PNEQRPLREEVLPKEGVASKEEVTLKEELPP 525
P P + + +P+ + + P P+ R +E K+ K++ K++
Sbjct: 767 PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHK 826
Query: 526 KEEVAPKEEVPPIERAFAQKTRPIKPPPDS---QETLALPSLVPQNYTENKNE 575
K + KE+ A A I + +E +A P P+ TE++ E
Sbjct: 827 KHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPE--PKKETESEAE 877
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 63.9 bits (154), Expect = 4e-10
Identities = 92/369 (24%), Positives = 128/369 (34%), Gaps = 50/369 (13%)
Query: 225 SQEEEHSSPVKAPSVK------RTPMPDKTATPERPPAPENAPSSKKIPAPD------KV 272
SQ E P KAP + + P P+ T P++PP PE KK P P+ K
Sbjct: 48 SQPELSEHPKKAPLPEFGAVSLKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKP 107
Query: 273 PSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPED-----KASIPENSIIPEET 327
P PE T + + + S K P P P K + PE KAS+PE +
Sbjct: 108 PPPEVTDLPKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVGEAPLKASLPEPGAPARKP 167
Query: 328 LTVDKPSTPERVFSVEESPAL----------EAPPMDKVPNPKMAPLGDEAPTLEKVLTP 377
L D+ S P R S +S A EA P P P P V
Sbjct: 168 LQPDELSHPARPPSEPKSGAFPRKLWQPEAGEATPRSPQPELSTFPKKPAQPEF-NVYPK 226
Query: 378 ELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAP-------PPQPP 430
+ + +V EA Q + +P A +A P +PP
Sbjct: 227 KPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPP 286
Query: 431 SSERCLGEMKCTLVRGDSSPRQAEL--KSGPASRPALEKPHPHEEATTLPEEAPSND-ER 487
E LG+ L R S P + L + PA AL K P E LP + +
Sbjct: 287 QPE--LGD----LTRTSSEPEVSVLPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNS 340
Query: 488 TPEEEAPPNEQRPLREEVLPKEGVASKEEVTLK-----EELPPKEEVAPKEEVPPIERAF 542
P + P + P R+ P+ K + PP A + +P F
Sbjct: 341 LPRKLLQPERRGPPRKFSQPEPSAVLKRHPQPEFFGDLPRKPPLPSSASESSLPAAVAGF 400
Query: 543 AQKTRPIKP 551
+ + P+ P
Sbjct: 401 SSR-HPLSP 408
Score = 51.6 bits (122), Expect = 2e-06
Identities = 89/382 (23%), Positives = 137/382 (35%), Gaps = 72/382 (18%)
Query: 224 SSQEEEHSSPVKAPS-----VKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKT 278
+SQ E P K P +K+ P+ + P++ P PE S K P P+ P+K
Sbjct: 24 ASQPEPSDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFGAVSLKPPPPEVTDLPKK- 82
Query: 279 LTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPER 338
P P +V K P + +P+ PE T KPS E
Sbjct: 83 ------------------PPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLEL 124
Query: 339 VFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSE 398
++ P L A P + P + P EAP L L E R +Q
Sbjct: 125 SDLSKKFPQLGATPFPRKP---LQPEVGEAP-----LKASLPEPGAPARKPLQ------- 169
Query: 399 EALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSS--ERCLGEMKCTLVRGDSSPR--QAE 454
+E P PP +P S R L + + G+++PR Q E
Sbjct: 170 -----------------PDELSHPARPPSEPKSGAFPRKLWQPEA----GEATPRSPQPE 208
Query: 455 LKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPL--REEVLPKEGVA 512
L + P +PA + + + + P+ + P+ E Q PL + PK +
Sbjct: 209 LSTFP-KKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSS 267
Query: 513 SKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPP-PDSQETLALPSLVPQNYTE 571
+ + + L + P+ E+ + R ++ + P P E AL PQ
Sbjct: 268 AFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKPPQ---- 323
Query: 572 NKNEGVDVTSLRGEVESLRRAL 593
+ G+ TS E SL R L
Sbjct: 324 PELGGLPRTSSEPEFNSLPRKL 345
Score = 45.8 bits (107), Expect = 1e-04
Identities = 99/494 (20%), Positives = 158/494 (31%), Gaps = 76/494 (15%)
Query: 128 PPPPIKKLVPRKVVSRESAPIKEPKKLMPK--TSLPTV-KKLATATTGPSKAKTSRTP-- 182
PPPP +P+K E + PKK P T LP KL + + TP
Sbjct: 83 PPPPEVTDLPKKPPPPEVTDL--PKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPFP 140
Query: 183 ----SRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPS 238
+ + + S P G + P + P + + + P +
Sbjct: 141 RKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSGAFPRKLWQPEAGEA 200
Query: 239 VKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTL---TLGDKASIPGNSTSGK 295
R+P P+ + P++P PE KK P P P+K++ + A P
Sbjct: 201 TPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSS 260
Query: 296 IPAPDKVPTPEKMVTP--EDKASIPENSIIPEETLTVDKPST---PERVFSVEESPALEA 350
P D P+K P D P + + T T +P P+R E +
Sbjct: 261 EPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKK 320
Query: 351 PPMDK---VPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYF 407
PP + +P P + P K+L PE FS E
Sbjct: 321 PPQPELGGLPRTSSEPEFNSLP--RKLLQPERRGPP---------RKFSQPEPSA----- 364
Query: 408 VAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTL-----------VRGDSSPRQAELK 456
V K P + P PP +SE L G R L
Sbjct: 365 VLKRHPQPEFFGDLPRKPPLPSSASESSLPAAVAGFSSRHPLSPGFGAAGTPRWRSGGLV 424
Query: 457 SGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLR-------------- 502
+RP L HP P + + P P + + R
Sbjct: 425 HSGGARPGLRPSHPPRRRPLPPASSLGHPPAKPPLPPGPVDMQSFRRPSAASIDLRRTRS 484
Query: 503 ------EEVLPKEGVASKEEVTLKEELPPKEEVAP----KEEVPPIERAFAQKTRPIKPP 552
++ P++ E L +++ P+++ +P ++E P +++A RP + P
Sbjct: 485 AAGLHFQDRQPEDIPVPDEIYELYDDVEPRDDSSPSPKGRDEAPSVQQA---ARRPPQDP 541
Query: 553 PDSQETLALPSLVP 566
+E P +P
Sbjct: 542 ALRKEKDPQPQQLP 555
Score = 32.0 bits (71), Expect = 1.8
Identities = 47/224 (20%), Positives = 75/224 (33%), Gaps = 24/224 (10%)
Query: 180 RTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPS- 238
R P S S GF S PG TP+ RS + P PS
Sbjct: 380 RKPPLPSSASESSLPAAVAGFSSRHPLSPGF--GAAGTPRWRSGGLVHSGGARPGLRPSH 437
Query: 239 -VKRTPMPDKTAT---PERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSG 294
+R P+P ++ P +PP P + P ++ L S G
Sbjct: 438 PPRRRPLPPASSLGHPPAKPPLPPGPVDMQSFRRPSAA-----SIDLRRTRSAAGLHFQD 492
Query: 295 KIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMD 354
+ P+ +P P+++ D ++S PS R + A PP D
Sbjct: 493 R--QPEDIPVPDEIYELYDDVEPRDDS----------SPSPKGRDEAPSVQQAARRPPQD 540
Query: 355 KVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSE 398
+ P + P ++ L +L + E + R+ + F E
Sbjct: 541 PALRKEKDPQPQQLPPMDPKLLKQLRKAEKAEREFRKKFKFEGE 584
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 62.8 bits (151), Expect = 1e-09
Identities = 98/447 (21%), Positives = 147/447 (32%), Gaps = 49/447 (10%)
Query: 155 MPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNG-----GFQSGGSYHPG 209
+P +LP ++ P+ + T S+D KL P+G G + G P
Sbjct: 902 VPGHTLPWRTTRRPGSSSPAIRRLPDTGSKDGYKLPWTWDTPSGRGLAEGTPTAGKLGPT 961
Query: 210 RKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPS-SKKIPA 268
T++P + SP K +R P P AT PP P PS S P
Sbjct: 962 LGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRP--AATRTAPPTPSPGPSASPGPPG 1019
Query: 269 PDKVPSPEKTLT----LGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKA-SIPENSII 323
P + LT L +A+ TS P P P+ ++T D A S P++S++
Sbjct: 1020 PALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVV 1079
Query: 324 PEET--------------LTVDKPSTPERVFSVEESPALE-APPMDKVPNPKMAPLGDEA 368
P T LT D PSTP V S+ SP E P D P+ P
Sbjct: 1080 PALTPEPSPTPLPTLPKELTSD-PSTPSEVTSL--SPTSEQVPESDTTPDLDTTPYSSTV 1136
Query: 369 PTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPP-- 426
+ P S +T D + + + + V P++ TP
Sbjct: 1137 SEYSRSPDPSPSPHPTTTPDPTM-----APDPITTLNPTVTPHFPTTPHPTTTPHPTTIT 1191
Query: 427 -----PQPPSSERCLGEM-KCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEE 480
P P ++ + + T++ ++ Q P + P PHP TT P
Sbjct: 1192 HSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHP----TTTPHP 1247
Query: 481 AP-SNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIE 539
++ P+ P ++ +P T P P + P
Sbjct: 1248 TTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDP 1307
Query: 540 RAFAQKTRPIKPPPDSQETLALPSLVP 566
T P T PS P
Sbjct: 1308 TTTPYPTTTPDPTTTPHPTTPDPSSTP 1334
Score = 50.1 bits (118), Expect = 6e-06
Identities = 93/462 (20%), Positives = 148/462 (32%), Gaps = 61/462 (13%)
Query: 137 PRKVVSRESAPIKEP----------KKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDS 186
PR +R + P P L +S A + S A + P+ D
Sbjct: 995 PRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDP 1054
Query: 187 QKLTSRD---SGPNGGFQS-GGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRT 242
T+ D + P+ + S P + TP + S+P + S+ T
Sbjct: 1055 ASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPT 1114
Query: 243 P--MPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 300
+P+ TP+ P ++ S+ +PD PSP T T + +T P
Sbjct: 1115 SEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPH 1174
Query: 301 KVPTPEKMVTPEDKASIPENSIIPEETLT------------VDKPSTPERVFSVEE---S 345
TP TP +I +++IP+ T T + P+T + F+ + +
Sbjct: 1175 FPTTPHPTTTPH-PTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTT 1233
Query: 346 PALEAPPMDKVPNP------KMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSSEE 399
P P P+P M P P + P +T H ++
Sbjct: 1234 PHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTP 1293
Query: 400 ALQKVKYFVAKEDPSSQEEAHTPEAPPPQP------PSSERCLGEMKCTLVRGD--SSPR 451
+ DP++ T P P PSS + + G SSP
Sbjct: 1294 HPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPT 1353
Query: 452 QAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGV 511
A P +P+L HP T AP T + P E P E +
Sbjct: 1354 LA-----PTVKPSL---HPQ---LTFTAPAP----HTSTSQIPTLEPSPALESSPSRSST 1398
Query: 512 ASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPP 553
A+ + E+ P +P PP + + P P
Sbjct: 1399 ATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDP 1440
>gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo
sapiens]
Length = 740
Score = 62.8 bits (151), Expect = 1e-09
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 22/143 (15%)
Query: 1 MIKEIEDGWWLGKKNG--QLGAFPSNFVELLDSGPPSLGNP----DMP-------SVSPG 47
+++++++ W+ G+ G + G FP +V+++ P + NP D+P S +
Sbjct: 602 LLRQVDENWYEGRIPGTSRQGIFPITYVDVIKR--PLVKNPVDYMDLPFSSSPSRSATAS 659
Query: 48 PQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDK 107
PQ+P PD QT Y+ L+ Y P+ DEL LR GD+V V+ K D
Sbjct: 660 PQQPQAQQRRV---TPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKC--DD 714
Query: 108 GWWEGECQGRR--GVFPDNFVLP 128
GW+ G + + G FP N+V P
Sbjct: 715 GWFVGTSRRTKQFGTFPGNYVKP 737
Score = 53.1 bits (126), Expect = 8e-07
Identities = 24/65 (36%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Query: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKL 135
R FD++ + EL L++GD+V + + D+ W+EGE GR G+FP ++ PP +K
Sbjct: 505 RAKFDFKAQTLKELPLQKGDIVYIYKQI--DQNWYEGEHHGRVGIFPRTYIELLPPAEKA 562
Query: 136 VPRKV 140
P+K+
Sbjct: 563 QPKKL 567
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/182 (23%), Positives = 84/182 (46%), Gaps = 36/182 (19%)
Query: 3 KEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSP 62
K+I+ W+ G+ +G++G FP ++ELL PP+ +P KL+
Sbjct: 530 KQIDQNWYEGEHHGRVGIFPRTYIELL---PPA-----------EKAQPKKLTP------ 569
Query: 63 PDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQG--RRGV 120
+Q + + E F++ + E++ R+G+ + +L + D+ W+EG G R+G+
Sbjct: 570 ---VQVLEYGEAI-AKFNFNGDTQVEMSFRKGERITLLRQV--DENWYEGRIPGTSRQGI 623
Query: 121 FPDNF--VLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKT 178
FP + V+ P +K V + S+P + T+ P + P +++T
Sbjct: 624 FPITYVDVIKRPLVKNPVDYMDLPFSSSPSRS------ATASPQQPQAQQRRVTPDRSQT 677
Query: 179 SR 180
S+
Sbjct: 678 SQ 679
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.127 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,716,679
Number of Sequences: 37866
Number of extensions: 2152643
Number of successful extensions: 19215
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 357
Number of HSP's successfully gapped in prelim test: 1480
Number of HSP's that attempted gapping in prelim test: 10791
Number of HSP's gapped (non-prelim): 6457
length of query: 645
length of database: 18,247,518
effective HSP length: 109
effective length of query: 536
effective length of database: 14,120,124
effective search space: 7568386464
effective search space used: 7568386464
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.