BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] (917 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 1808 0.0 gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 1808 0.0 gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 1800 0.0 gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 605 e-173 gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 548 e-155 gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 546 e-155 gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 535 e-152 gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 528 e-150 gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 472 e-133 gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 471 e-132 gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 470 e-132 gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 470 e-132 gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 458 e-128 gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 458 e-128 gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 450 e-126 gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 442 e-124 gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 383 e-106 gi|113413200 PREDICTED: similar to protein expressed in prostate... 353 4e-97 gi|88953571 PREDICTED: similar to protein expressed in prostate,... 351 2e-96 gi|153791352 prostate, ovary, testis expressed protein on chromo... 348 1e-95 gi|134133226 protein expressed in prostate, ovary, testis, and p... 348 1e-95 gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 330 5e-90 gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 314 2e-85 gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo... 310 3e-84 gi|52856430 protein expressed in prostate, ovary, testis, and pl... 303 4e-82 gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ... 301 1e-81 gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor... 299 7e-81 gi|239747114 PREDICTED: hypothetical protein XP_002343914 isofor... 299 7e-81 gi|153792284 pote protein [Homo sapiens] 299 9e-81 gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens] 295 2e-79 >gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] Length = 917 Score = 1808 bits (4683), Expect = 0.0 Identities = 917/917 (100%), Positives = 917/917 (100%) Query: 1 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL 60 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL Sbjct: 1 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL 60 Query: 61 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC 120 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC Sbjct: 61 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC 120 Query: 121 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN 180 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN Sbjct: 121 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN 180 Query: 181 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA 240 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA Sbjct: 181 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA 240 Query: 241 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE 300 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE Sbjct: 241 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE 300 Query: 301 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT 360 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT Sbjct: 301 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT 360 Query: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK 420 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK Sbjct: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK 420 Query: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480 Query: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540 Query: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600 Query: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL Sbjct: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660 Query: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL 720 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL 720 Query: 721 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ 780 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ Sbjct: 721 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ 780 Query: 781 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK 840 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK Sbjct: 781 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK 840 Query: 841 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG 900 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG Sbjct: 841 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG 900 Query: 901 QMRSQVCMKLSMSTVTL 917 QMRSQVCMKLSMSTVTL Sbjct: 901 QMRSQVCMKLSMSTVTL 917 >gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo sapiens] Length = 917 Score = 1808 bits (4683), Expect = 0.0 Identities = 917/917 (100%), Positives = 917/917 (100%) Query: 1 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL 60 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL Sbjct: 1 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL 60 Query: 61 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC 120 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC Sbjct: 61 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC 120 Query: 121 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN 180 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN Sbjct: 121 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN 180 Query: 181 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA 240 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA Sbjct: 181 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA 240 Query: 241 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE 300 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE Sbjct: 241 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE 300 Query: 301 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT 360 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT Sbjct: 301 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT 360 Query: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK 420 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK Sbjct: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK 420 Query: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480 Query: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540 Query: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600 Query: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL Sbjct: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660 Query: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL 720 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL 720 Query: 721 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ 780 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ Sbjct: 721 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ 780 Query: 781 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK 840 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK Sbjct: 781 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK 840 Query: 841 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG 900 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG Sbjct: 841 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG 900 Query: 901 QMRSQVCMKLSMSTVTL 917 QMRSQVCMKLSMSTVTL Sbjct: 901 QMRSQVCMKLSMSTVTL 917 >gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo sapiens] Length = 917 Score = 1800 bits (4663), Expect = 0.0 Identities = 913/917 (99%), Positives = 915/917 (99%) Query: 1 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL 60 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL Sbjct: 1 MEVRGSFLAACRRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILL 60 Query: 61 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC 120 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC Sbjct: 61 RLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVC 120 Query: 121 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN 180 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN Sbjct: 121 ASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVN 180 Query: 181 RKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA 240 RKKEQMV+FLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA Sbjct: 181 RKKEQMVAFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTA 240 Query: 241 EDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE 300 EDYAVASKFQAIRGMISEYKANKR KSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE Sbjct: 241 EDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEE 300 Query: 301 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT 360 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT Sbjct: 301 KMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKT 360 Query: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSK 420 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLI+QSGMECKDFVSLSK Sbjct: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSK 420 Query: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480 Query: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540 Query: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600 Query: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660 EDLEKTLKRNEE LTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL Sbjct: 601 EDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660 Query: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL 720 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETEL 720 Query: 721 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ 780 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ Sbjct: 721 HYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQ 780 Query: 781 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK 840 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK Sbjct: 781 SQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLK 840 Query: 841 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG 900 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG Sbjct: 841 ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLG 900 Query: 901 QMRSQVCMKLSMSTVTL 917 QMRSQVCMKLSMSTVTL Sbjct: 901 QMRSQVCMKLSMSTVTL 917 >gi|154354990 ankyrin repeat domain 26 [Homo sapiens] Length = 1710 Score = 605 bits (1561), Expect = e-173 Identities = 358/758 (47%), Positives = 480/758 (63%), Gaps = 118/758 (15%) Query: 266 KSLQNSNS-EQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVH--ADDSD 322 K +Q S + E DLE+ SE EQER EG E++QPQVEE+ KK RN +MEVS N+H A D Sbjct: 514 KDVQTSKAAEHDLEVASEEEQER-EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDA 572 Query: 323 NYNDDVDELIHKIKNRKPDNHQSPGKENGEFD------RLARKTSNEKSK---------- 366 +DD D LI K K+ + D+ Q P KEN E+ ++ S EK K Sbjct: 573 EDDDDDDGLIQKRKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSP 632 Query: 367 -----------------------------------------VKSQIYFTDDLNDISGSSE 385 VK+QI DD++D++ SSE Sbjct: 633 VFGKASLLTGGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSE 692 Query: 386 KTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVK 445 SED ELP+S +NFMLLI+Q GMECKD VSL K ++A +C R +E +K +CE L VK Sbjct: 693 TASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVK 752 Query: 446 FQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKD 505 +KM++ ++VLQ+ LSET + KSQ EHQ ++ +++LC+LRF L Q+EE+R A+ LYEK Sbjct: 753 IKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKI 812 Query: 506 IEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQ------------------- 546 E+L+ EEQYR + EVK+Q +L+L++LE+EL+TV+SN NQ Sbjct: 813 REQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNAR 872 Query: 547 ---------------------------NFHTHERERDLWQENHLMRDEIARLRLEIDTIK 579 N H+HE E+DL +N ++++EIA LRLEIDTIK Sbjct: 873 MLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIK 932 Query: 580 HQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSEL 639 +QNQE E K F+D++I+KE NEDL+KT+K+NEETLT+TI++Y+ L+VL EN MLNS+L Sbjct: 933 NQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKL 992 Query: 640 QKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHI 699 + EKQS RLE E+ESY RLAAA+ D DQ ++SKR+L+LAFQ +E LQ+ N + Sbjct: 993 ENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDV 1052 Query: 700 -------QILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIE 752 +ILSQQL K ES + LE E H+ R+AL+EKTL +E +Q LS+TQ +++++E Sbjct: 1053 SNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEME 1112 Query: 753 HMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCE 812 YQN+Q + KY+ KQ+SVE+ L QLQS+N+L +QQ +DA KADN+EKT+INIQ + Sbjct: 1113 QKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFH 1172 Query: 813 DTVEKLQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDAL 868 V+KLQAE K LEE NK L+ EC LKERQ QYE EK EREVV RQLQ+E+ D L Sbjct: 1173 AIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTL 1232 Query: 869 NKQLLLEAMLEISSERRINLEDEAQSLKKKLGQMRSQV 906 KQ + EA LE++S RINLEDE Q LKKKLGQ+R+Q+ Sbjct: 1233 KKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQL 1270 Score = 251 bits (641), Expect = 2e-66 Identities = 261/1009 (25%), Positives = 443/1009 (43%), Gaps = 189/1009 (18%) Query: 5 GSFLAACRRRMATWRKNRDKDG-FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLN 63 GSF A R+R + +G +S PGY VR +DLG IHKAA AG+V KV + +LLR N Sbjct: 14 GSF--ARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKN 71 Query: 64 DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASI 123 LNDRDK NRTAL LACA+G P VV LV RKCQLN+ D+ENRTAL+KAVQCQEE CA+I Sbjct: 72 GLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATI 131 Query: 124 LLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKK 183 LLEHGA+PN+ D++GNTALHYA+ NE+IS+A KLL Y A+IEA+++D T LLLAV+ KK Sbjct: 132 LLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKK 191 Query: 184 EQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDY 243 +QMV FL+KKK ++ A+D Sbjct: 192 QQMVEFLIKKKANVNAVD------------------------------------------ 209 Query: 244 AVASKFQAIRGMISEYKANKRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEK- 301 K ++ +ISEYK + K S QNSNS + S G + S P +++ Sbjct: 210 ----KLESSHQLISEYKEERIPKHSSQNSNSVDESSEDSLSRLSGKPGVDDSWPTSDDED 265 Query: 302 ------------MKKCRNKKMEVSRNVHAD---------------DSDNYNDDVDELIH- 333 + K + +N+ A DSD+ ++ V E + Sbjct: 266 LNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVESLPT 325 Query: 334 ---KIKNRKPDNHQSPG---------------------------KENGEFDRL----ARK 359 K++ +QSP KENG D + + Sbjct: 326 TSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEEPTKPGIAKKENG-IDIIESAPLEQ 384 Query: 360 TSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLS 419 T+N+ +++ + + +S ED E P+ D E+ Q ++ + Sbjct: 385 TNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW-DSESISENFPQKYVDPLAGAADG 443 Query: 420 KSKNATAACGRSIED----QKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNL 475 K KN ED C K K+++ +V V ++ Sbjct: 444 KEKNIG---NEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVGMPV-------------AHM 487 Query: 476 QGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQ---SKLTLKS 532 + ++ +L+ ++ ++ KA + KD++ K E +E +++ S+ Sbjct: 488 ESPERYLHLKPTIEMKDSVPNKAGGM--KDVQTSKAAEHDLEVASEEEQEREGSENNQPQ 545 Query: 533 LEVELKTVRSNSNQ-NFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFK 591 +E E K R+N + + + H+ D +++ D + + R +T Q ENK + Sbjct: 546 VEEERKKHRNNEMEVSANIHDGATDDAEDDD-DDDGLIQKRKSGETDHQQFPRKENKEYA 604 Query: 592 DIEIIKENNE--DLEKTLKRNEETLTKTITRYSKELN---VLMDENTMLNSELQKEKQSM 646 + E EK + ++E++ + + L + +D+++ L+ + E + Sbjct: 605 SSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGRPT 664 Query: 647 SRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQL 706 + E + ++ + D QSS+ T +E C L + + +L +QL Sbjct: 665 KKTSNEKNKVKNQIQSMDDVDDLTQSSE---------TASEDCELPHSSYKNFMLLIEQL 715 Query: 707 S----------KAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQ 756 K + + E L ++ + T+ I+ M+ ++ QR L + + + Sbjct: 716 GMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKS 775 Query: 757 NDQPILEKYVRKQQSVEDGLFQLQSQ----NLLYQQQCNDARKKADNQEKTIINIQVKCE 812 + ++ R+ S+ L Q + + + LY++ R+K + K + ++ + E Sbjct: 776 QLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKE-VEVKQQLE 834 Query: 813 DTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDA----- 867 +++ L+ E R ++ N Q E+ +R++ R Q R + D Sbjct: 835 LSLQTLEMELRTVKSN------------LNQVVQERNDAQRQLSREQNARMLQDGILTNH 882 Query: 868 LNKQLLLEAMLEISSERRINLEDEAQSLKKKLGQMRSQVCM-KLSMSTV 915 L+KQ +E + + + +E + L K ++ ++ M +L + T+ Sbjct: 883 LSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTI 931 Score = 68.2 bits (165), Expect = 3e-11 Identities = 98/509 (19%), Positives = 211/509 (41%), Gaps = 72/509 (14%) Query: 450 KNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAE--ELYEKDIE 507 + I + QK ++ ++ + S E ++L K + + + E + IK + E +K E Sbjct: 886 QKEIEMAQKKMN-SENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFE 944 Query: 508 ELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDE 567 +LKI++E+ + + T+K E L S N E + L ++ Sbjct: 945 DLKIVKEK-------NEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSK-LENEK 996 Query: 568 IARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNV 627 ++ RLE + + ++ + +D + + +LE +R + ++ + + +++ Sbjct: 997 QSKERLEAEVESYHSRLAAAIHDRDQS--ETSKRELELAFQRARDECSRLQDKMNFDVSN 1054 Query: 628 LMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALC-------DHDQRQSSKRDLQLA 680 L D N +L+ +L K + ++ LE E R L D Q Q ++++ Sbjct: 1055 LKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQK 1114 Query: 681 FQST---VNEWCHLQEDTNSHIQ-------ILSQQLSKA-------ESTSSGLETELH-- 721 +Q+ VN++ QE + +L QQL A E T ++ + H Sbjct: 1115 YQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAI 1174 Query: 722 ---YEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVR----------K 768 + E+ K+ L E + ++S L++ ++ Y+N++ E VR K Sbjct: 1175 VQKLQAESEKQSLLLEERNKELISECNH-LKERQYQYENEKAEREVVVRQLQQELADTLK 1233 Query: 769 QQSVEDGLFQLQSQ-NLLYQQQCNDARKK----------ADNQEKTIINIQVKCEDTVEK 817 +QS+ + ++ S+ + + + D +KK A ++ + K +D +K Sbjct: 1234 KQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQK 1293 Query: 818 LQAECRKLEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAM 877 L+ + KL+ K M + L++ ++E+E +++ ++ + LE Sbjct: 1294 LEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQS--------LECN 1345 Query: 878 LEISSERRINLEDEAQSLKKKLGQMRSQV 906 L+ ++ + LE E K L R ++ Sbjct: 1346 LDQEMKKNVELEREITGFKNLLKMTRKKL 1374 Score = 67.8 bits (164), Expect = 4e-11 Identities = 129/694 (18%), Positives = 288/694 (41%), Gaps = 92/694 (13%) Query: 258 EYKANKRRKSLQNSNS---EQDLEMTSEGEQE-----RLEGCESSQPQVEEKMKKC---- 305 E + +++ + +NS+S E+DL + QE RLE ++ + Q +EK KKC Sbjct: 888 EIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLE-IDTIKNQNQEKEKKCFEDL 946 Query: 306 ---RNKKMEVSRNVHADDS------DNYNDDVDELI--HKIKNRKPDNHQSPGKENGEFD 354 + K ++ + + ++ YN + L + + N K +N E + Sbjct: 947 KIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLEN------EKQSKE 1000 Query: 355 RLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKD 414 RL + + S++ + I+ D SE + + EL + + + S ++ K Sbjct: 1001 RLEAEVESYHSRLAAAIHDRDQ-------SETSKRELELAFQRARD-----ECSRLQDKM 1048 Query: 415 FVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQN 474 +S K+ + + + L+++F ++ + L K SQ++ Sbjct: 1049 NFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQ--- 1105 Query: 475 LQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLE 534 C ++ + Q+ + E++K + K + + + +++Q + Sbjct: 1106 -------CQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKAD 1158 Query: 535 VELKTVRSNSNQNFHT--HERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKD 592 + KTV N FH + + + +++ L+ + L E + +K + + EN+ + Sbjct: 1159 NKEKTV-INIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAER 1217 Query: 593 IEIIKENNEDLEKTLKRNE--ETLTKTITRYSKELNVLMDENTMLNSEL-QKEKQSMSRL 649 ++++ ++L TLK+ E + +RY L DE L +L Q Q Sbjct: 1218 EVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLE---DETQDLKKKLGQIRNQLQEAQ 1274 Query: 650 ETEMESYRCRLAAALCDHDQR-QSSKRDLQLAFQSTVNEWCHLQEDT-NSHI-QILSQQL 706 + E+ RC A + DH Q+ + L++ + +++ LQ++ N+++ + +QL Sbjct: 1275 DRHTEAVRC--AEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQL 1332 Query: 707 SKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYV 766 K LE L E + E I + +L T+++L + Y+N + + Sbjct: 1333 KKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNE----YENGEFSFHGDL 1388 Query: 767 RKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKL------QA 820 + Q F++ Q + + +D + + +++ K + E+L Q Sbjct: 1389 KTSQ------FEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQK 1442 Query: 821 ECRKLEENNKGLMKECTLLK----ERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEA 876 +C KL++N K L +E L+ + + K+ ++ + + ++E+ + L + + Sbjct: 1443 KCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKE---VNL 1499 Query: 877 MLEISSERRINLEDEAQSLKKKLGQMRSQVCMKL 910 L+ + + NLE Q + M+SQ+ +++ Sbjct: 1500 FLQAQAASQENLE---QFRENNFASMKSQMELRI 1530 >gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH polyclonal antibodies [Homo sapiens] Length = 1430 Score = 548 bits (1411), Expect = e-155 Identities = 329/692 (47%), Positives = 440/692 (63%), Gaps = 37/692 (5%) Query: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298 + + A K IRG +S ++R+ +L+ + E+D E + E + PQ Sbjct: 689 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 744 Query: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343 + K KK + ++ + Y +++ L I+N+ K Sbjct: 745 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 804 Query: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397 +P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + + Sbjct: 805 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 863 Query: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457 +N +LLI Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ Sbjct: 864 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 923 Query: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517 K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR Sbjct: 924 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 983 Query: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577 + +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT Sbjct: 984 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 1042 Query: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637 IK+QN E KY KD EI+K +EDL+K LKRNEETL +TI YS +L L DENT L S Sbjct: 1043 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 1100 Query: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697 +L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS Sbjct: 1101 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 1160 Query: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757 H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++ Sbjct: 1161 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 1220 Query: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817 +EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE Sbjct: 1221 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 1276 Query: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873 LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK+ Sbjct: 1277 LQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSA 1336 Query: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905 +A+L+ SS I LE+ Q +KKL QMRSQ Sbjct: 1337 TKALLDASSRHCIYLENGMQDSRKKLDQMRSQ 1368 >gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH polyclonal antibodies [Homo sapiens] Length = 868 Score = 546 bits (1408), Expect = e-155 Identities = 329/692 (47%), Positives = 439/692 (63%), Gaps = 37/692 (5%) Query: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298 + + A K IRG +S ++R+ +L+ + E+D E + E + PQ Sbjct: 127 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182 Query: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343 + K KK + ++ + Y +++ L I+N+ K Sbjct: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242 Query: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397 +P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + + Sbjct: 243 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 301 Query: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457 +N +LLI Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ Sbjct: 302 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 361 Query: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517 K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR Sbjct: 362 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 421 Query: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577 + +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT Sbjct: 422 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 480 Query: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637 IK+QN E KY KD EI+K +EDL+K LKRNEETL +TI YS +L L DENT L S Sbjct: 481 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 538 Query: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697 +L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS Sbjct: 539 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 598 Query: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757 H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++ Sbjct: 599 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 658 Query: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817 +EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE Sbjct: 659 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 714 Query: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873 LQAECRK LEE+NK L+ E T KE++CQYEKEK EREV RQLQ++ DD LNK Sbjct: 715 LQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 774 Query: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905 +A+L+ SS LE+ Q +KKL QMRSQ Sbjct: 775 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 806 >gi|124517695 ankyrin repeat domain 36B [Homo sapiens] Length = 1121 Score = 535 bits (1379), Expect = e-152 Identities = 325/692 (46%), Positives = 435/692 (62%), Gaps = 37/692 (5%) Query: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298 + + A K IRG +S ++RR +L+ + E+D E + E + PQ Sbjct: 380 SVSNIATEIKDGQIRGTVS----SQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQK 435 Query: 299 EEKMKKCRNKKMEVSRNVH-----ADDSDNYNDDVDELIHKIKNR----------KPDNH 343 + K KK+ + Y +++ L I+N+ K Sbjct: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQT 495 Query: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397 +P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + + Sbjct: 496 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 554 Query: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457 +N +LLI Q M+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQ Sbjct: 555 CKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQ 614 Query: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517 K +SE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR Sbjct: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674 Query: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577 + +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT Sbjct: 675 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 733 Query: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637 IK+QN E KY KD EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S Sbjct: 734 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRS 791 Query: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697 +L+K+++S RLETEM+SYRCRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NS Sbjct: 792 KLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNS 851 Query: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757 H+ ILS QLSKAES S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++ Sbjct: 852 HVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 911 Query: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817 +EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+ Sbjct: 912 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQN 967 Query: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873 LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK Sbjct: 968 LQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 1027 Query: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905 +A+L+ SS LE+ Q +KKL QMRSQ Sbjct: 1028 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 1059 >gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] Length = 1524 Score = 528 bits (1361), Expect = e-150 Identities = 299/559 (53%), Positives = 387/559 (69%), Gaps = 12/559 (2%) Query: 351 GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGM 410 GE RL + N + +VK+QI+ DDL+DI SS+ SED + + +N +LLI Q M Sbjct: 912 GEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEM 970 Query: 411 ECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQS 470 +CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQK +SE ++ KSQ Sbjct: 971 KCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 1030 Query: 471 EHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTL 530 +H+ L+ +K+LC+LRF +QQ++++R EE+++K E+L+I EEQYR + +V K K L Sbjct: 1031 KHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090 Query: 531 KSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYF 590 KS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DTIK+QN E KY Sbjct: 1091 KSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYL 1147 Query: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLE 650 KD EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S+L+K+++S RLE Sbjct: 1148 KDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLE 1207 Query: 651 TEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAE 710 TEM+SY CRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NSH+ ILS QLSKAE Sbjct: 1208 TEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAE 1267 Query: 711 STSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQ 770 S S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++ +EK + KQ+ Sbjct: 1268 SKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE 1327 Query: 771 SVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK----LE 826 QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+ LQAECRK LE Sbjct: 1328 R----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLE 1383 Query: 827 ENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRI 886 E+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK +A+L+ SS Sbjct: 1384 EDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT 1443 Query: 887 NLEDEAQSLKKKLGQMRSQ 905 LE+ Q +KKL QMRSQ Sbjct: 1444 YLENGMQDSRKKLDQMRSQ 1462 >gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens] Length = 823 Score = 472 bits (1215), Expect = e-133 Identities = 312/839 (37%), Positives = 472/839 (56%), Gaps = 68/839 (8%) Query: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 ++ GYR+R +L IH+AA+ GD +V + R DL+ DK++RTAL LACA G Sbjct: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQ 81 Query: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 Query: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLK+K A+D R+ Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRS 201 Query: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 Query: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 Query: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 N +++ P H S K + E + A K + ++ V++ + Sbjct: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364 Query: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440 SE+++ + E +K+ K + + LS++ ++AA GR + +K Sbjct: 365 PVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 + K + K + EH R L+Q+ EE+ Sbjct: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N++FH HE + L E Sbjct: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE 513 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 574 YQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 Query: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733 + T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L Sbjct: 634 LERTRD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691 Query: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793 +E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D Sbjct: 692 LETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751 Query: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 +K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 752 HQKEDHKE-IVTNIQRGFIESGKKDLV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 >gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens] Length = 823 Score = 471 bits (1213), Expect = e-132 Identities = 312/839 (37%), Positives = 472/839 (56%), Gaps = 68/839 (8%) Query: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 ++ GYR+R +L IH+AA+ GD +V + R DL+ DK++RTAL LACA G Sbjct: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQ 81 Query: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 Query: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLK+K A+D R+ Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRS 201 Query: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 Query: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 Query: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 N +++ P H S K + E + A K + ++ V++ + Sbjct: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364 Query: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440 SE+++ + E +K+ K + + LS++ ++AA GR + +K Sbjct: 365 PVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 + K + K + EH R L+Q+ EE+ Sbjct: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N++FH HE + L E Sbjct: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE 513 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 574 YQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 Query: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733 + T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L Sbjct: 634 LERTRD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691 Query: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793 +E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D Sbjct: 692 LETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751 Query: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 +K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 752 HQKEDHKE-IVTNIQRGFIESGKKDLV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 >gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sapiens] Length = 823 Score = 470 bits (1210), Expect = e-132 Identities = 312/839 (37%), Positives = 471/839 (56%), Gaps = 68/839 (8%) Query: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 ++ GYR+R +L IH+AA+ GD +V + R +L+ DK++RTAL LACA G Sbjct: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQ 81 Query: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 Query: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLKKK A+D R+ Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRS 201 Query: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 Query: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 Query: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 N +++ P H S K + E + A K + ++ V++ + Sbjct: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364 Query: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440 SE+++ + E +K+ K + + LS++ ++AA GR + +K Sbjct: 365 PVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 + K + K + EH R L+Q+ EE+ Sbjct: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N +FH HE + L E Sbjct: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDE 513 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 574 YQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 Query: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733 + T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L Sbjct: 634 LERTQD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691 Query: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793 +E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D Sbjct: 692 LETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751 Query: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 +K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 752 HQKEDHKE-IVTNIQRGFIESGKKDFV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 >gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sapiens] Length = 823 Score = 470 bits (1209), Expect = e-132 Identities = 310/837 (37%), Positives = 466/837 (55%), Gaps = 64/837 (7%) Query: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 ++ GYR+R +L IH+AA+ GD +V + R DL+ DK++RTAL LAC G Sbjct: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACTSGHVQ 81 Query: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 Query: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLKKK A+D R+ Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRS 201 Query: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 Query: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 Query: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 N +++ P H S K + E + A K + ++ V++ + Sbjct: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364 Query: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440 SE+++ + E +K+ K + + LS++ ++AA GR + +K Sbjct: 365 PVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 + K + K + EH R L+Q+ EE+ Sbjct: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N +FH HE + L E Sbjct: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDE 513 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 574 YQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 Query: 681 FQSTVN-----EWCHLQEDTNSHIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIE 735 + T + E + + L++QLS+ + + L+ + R++L++K+L +E Sbjct: 634 LERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALE 693 Query: 736 HMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARK 795 +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D + Sbjct: 694 TVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQ 753 Query: 796 KADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 754 KEDHKE-IVTNIQRGFIESGKKDLV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 >gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5 [Homo sapiens] Length = 823 Score = 458 bits (1178), Expect = e-128 Identities = 309/841 (36%), Positives = 464/841 (55%), Gaps = 66/841 (7%) Query: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 ++ GYR+R +L IHKAA+ GD ++ + R DL+ DK++RTAL LACA G Sbjct: 22 YTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVK 81 Query: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 82 VVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 Query: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 +E+ S+A KLL +G +IEA +D +T LL A+ KKE+MV FLLK K A+D T Sbjct: 142 YSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRLRXT 201 Query: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266 AL+LA S +V LL+ +I+VF QD+ G AEDYA++ + I+ I E+ K Sbjct: 202 ALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEH------K 255 Query: 267 SLQNSNSEQDLEMTSEGEQERL-EGCESSQPQVEEKM-----KKCRNKKMEVSRNVHADD 320 + N + D+ + E E C S +++++ K+C +K VS + Sbjct: 256 KMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEK--VSEPLRGPS 313 Query: 321 SDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDI 380 N +++ P H S L T E VK + + Sbjct: 314 HGKGN----RIVNGKGEGPPAKHPS----------LKPSTEMEDPAVKGAVQXKN----- 354 Query: 381 SGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCE 440 + + LP + +E + K + + N + + + C+ Sbjct: 355 ---VQTLRAEQALPVASEEEQQRRERSE----KKQPQVIEGNNTYKSEKIQLSENICHST 407 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 F + ++ +K+ KT Q + L+ + C L+ Q+ EE+ Sbjct: 408 -----FSAAADRLTQQRKI----GKTYPQQFPKKLKEEHDRCTLK----QENEEKTNVNM 454 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 L++K+ EEL+ E+QY+ + E K Q + T++SLE++ KT R+ NQ+FH HE +DL E Sbjct: 455 LHKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDE 513 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ +IA LR EI T+K+ N E ENKY KDI+I KE N LEK +K NEE +TKT Sbjct: 514 NCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFW 573 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y +ELN L ENT LNSEL KEK+S +LE E+ESY+ RLAAA+ H + ++R+L+LA Sbjct: 574 YQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLA 633 Query: 681 FQST--VNEWCHLQEDTNSHIQ----ILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734 + T ++E + D S I+ L++QLSK + + L+ + R+ L++K+L + Sbjct: 634 LERTQDISEQVKMSSDI-SEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLAL 692 Query: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794 E +Q LS+TQ+++++++ MYQ+ + + K K VE+ + QLQ +N +QQ D Sbjct: 693 ETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVH 752 Query: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEERE 854 +K D++E +INIQ +E + + LEE NK LM E LKE QYE++K E Sbjct: 753 QKEDHKE-IVINIQ---RGFIESRKKDL-MLEEKNKKLMNEYDHLKESLFQYERQKAETV 807 Query: 855 V 855 V Sbjct: 808 V 808 >gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5 [Homo sapiens] Length = 823 Score = 458 bits (1178), Expect = e-128 Identities = 309/841 (36%), Positives = 464/841 (55%), Gaps = 66/841 (7%) Query: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 ++ GYR+R +L IHKAA+ GD ++ + R DL+ DK++RTAL LACA G Sbjct: 22 YTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVK 81 Query: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 82 VVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 Query: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 +E+ S+A KLL +G +IEA +D +T LL A+ KKE+MV FLLK K A+D T Sbjct: 142 YSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRLRXT 201 Query: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266 AL+LA S +V LL+ +I+VF QD+ G AEDYA++ + I+ I E+ K Sbjct: 202 ALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEH------K 255 Query: 267 SLQNSNSEQDLEMTSEGEQERL-EGCESSQPQVEEKM-----KKCRNKKMEVSRNVHADD 320 + N + D+ + E E C S +++++ K+C +K VS + Sbjct: 256 KMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEK--VSEPLRGPS 313 Query: 321 SDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDI 380 N +++ P H S L T E VK + + Sbjct: 314 HGKGN----RIVNGKGEGPPAKHPS----------LKPSTEMEDPAVKGAVQXKN----- 354 Query: 381 SGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCE 440 + + LP + +E + K + + N + + + C+ Sbjct: 355 ---VQTLRAEQALPVASEEEQQRRERSE----KKQPQVIEGNNTYKSEKIQLSENICHST 407 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 F + ++ +K+ KT Q + L+ + C L+ Q+ EE+ Sbjct: 408 -----FSAAADRLTQQRKI----GKTYPQQFPKKLKEEHDRCTLK----QENEEKTNVNM 454 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 L++K+ EEL+ E+QY+ + E K Q + T++SLE++ KT R+ NQ+FH HE +DL E Sbjct: 455 LHKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDE 513 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ +IA LR EI T+K+ N E ENKY KDI+I KE N LEK +K NEE +TKT Sbjct: 514 NCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFW 573 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y +ELN L ENT LNSEL KEK+S +LE E+ESY+ RLAAA+ H + ++R+L+LA Sbjct: 574 YQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLA 633 Query: 681 FQST--VNEWCHLQEDTNSHIQ----ILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734 + T ++E + D S I+ L++QLSK + + L+ + R+ L++K+L + Sbjct: 634 LERTQDISEQVKMSSDI-SEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLAL 692 Query: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794 E +Q LS+TQ+++++++ MYQ+ + + K K VE+ + QLQ +N +QQ D Sbjct: 693 ETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVH 752 Query: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEERE 854 +K D++E +INIQ +E + + LEE NK LM E LKE QYE++K E Sbjct: 753 QKEDHKE-IVINIQ---RGFIESRKKDL-MLEEKNKKLMNEYDHLKESLFQYERQKAETV 807 Query: 855 V 855 V Sbjct: 808 V 808 >gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo sapiens] Length = 475 Score = 450 bits (1158), Expect = e-126 Identities = 248/446 (55%), Positives = 317/446 (71%), Gaps = 11/446 (2%) Query: 414 DFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQ 473 D V L K KN R I+ + +CE+L+VK +K+KN SVLQK +SE ++ KSQ +H+ Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83 Query: 474 NLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSL 533 L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR + +V K K LKS Sbjct: 84 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 143 Query: 534 EVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDI 593 EVELKT +NSNQ T E+E DL EN LM+DEIARLRL+ DTIK+QN E KY KD Sbjct: 144 EVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLDTDTIKNQN--LEKKYLKDF 200 Query: 594 EIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEM 653 EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S+L+K+++S RLETEM Sbjct: 201 EIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEM 260 Query: 654 ESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTS 713 +SY CRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NSH+ ILS QLSKAES S Sbjct: 261 QSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKS 320 Query: 714 SGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVE 773 L+TELHY EALKEK L EH+Q L + Q +++DIE MY++ +EK + KQ+ Sbjct: 321 RVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQER-- 378 Query: 774 DGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK----LEENN 829 QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+ LQAECRK LEE+N Sbjct: 379 --FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDN 436 Query: 830 KGLMKECTLLKERQCQYEKEKEEREV 855 K L+ E KE++CQYEKEK EREV Sbjct: 437 KMLVNELNHSKEKECQYEKEKAEREV 462 Score = 31.6 bits (70), Expect = 3.5 Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 824 KLEENN-KGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISS 882 KL++N+ + L + LK + +K E+E ++ QL+ E+ + + L ++ Sbjct: 43 KLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEK 102 Query: 883 ERRINLEDEAQSLKKKL 899 ++R N+E+ Q +++KL Sbjct: 103 KKRRNVEELHQKVREKL 119 >gi|149363642 coiled-coil domain containing 144A [Homo sapiens] Length = 1427 Score = 442 bits (1138), Expect = e-124 Identities = 281/669 (42%), Positives = 397/669 (59%), Gaps = 77/669 (11%) Query: 298 VEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLA 357 VEE+M+K R+ E+S + D +D D L N Q P KENGE DR A Sbjct: 527 VEEEMEKHRSNSTELSGTL--TDGTTVGNDDDGL----------NQQIPRKENGEHDRPA 574 Query: 358 RKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVS 417 KTSNEK++VK+QIY D D SE SED EL +S ENFMLLI+Q ME KD S Sbjct: 575 DKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSAS 634 Query: 418 LSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQG 477 L + ++ C ++ + +C++L VK ++M+N +SVLQ LSET KTK Q E Q ++ Sbjct: 635 LPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEW 694 Query: 478 KKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVEL 537 +K+L +LR L+Q+ EE+ A+ LY KD E+L+I EE+ E K+Q K L+ L EL Sbjct: 695 EKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKEL 754 Query: 538 KTVRSN-------------------------------------------SNQNFHTHERE 554 +TVR+N +++ H H++E Sbjct: 755 RTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKE 814 Query: 555 RDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETL 614 +DL+ E+ ++++EIA LRLEIDTIK+QN++ E KYF+DIE +KE N++L+K +K NEETL Sbjct: 815 KDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETL 874 Query: 615 TKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSK 674 T+TI +YS +LN L EN +LNSEL+ KQ+ RLE EMESYRCRLAAA+ D DQ Q++ Sbjct: 875 TETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTA- 933 Query: 675 RDLQLAFQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREAL 727 RDL+L FQ T EW L + + +ILS++LS AES + L+ +LH R+AL Sbjct: 934 RDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDAL 993 Query: 728 KEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQ 787 ++L +E +Q LS+TQ + ++ E MYQ +Q L+KY+ KQ+SVE+ L QLQS+N+L + Sbjct: 994 GRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLR 1053 Query: 788 QQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK----LEENNKGLMKECTLLKERQ 843 QQ +DA KKA++QEKT IQ + + LQAE K L+E NK LM E LKER Sbjct: 1054 QQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERM 1113 Query: 844 CQYEKEKEEREVVRRQLQREVD------DALNKQLLLEAMLEISSERRINLEDEAQSLKK 897 Q EKEK R++ + Q V DA N+ L L+ L ++ + ++L+K Sbjct: 1114 DQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKA----IQKQCETLQK 1169 Query: 898 KLGQMRSQV 906 Q++ +V Sbjct: 1170 NKKQLKQEV 1178 Score = 62.0 bits (149), Expect = 2e-09 Identities = 145/717 (20%), Positives = 282/717 (39%), Gaps = 121/717 (16%) Query: 269 QNSNSEQDLEMTSEGEQERLEGCESSQP----QVEEKMKKCRNKKMEVSRNV-HADDSD- 322 ++ +EQD E+TSE EQERL+GCE+ QP Q E K C + + + + H S+ Sbjct: 218 ESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277 Query: 323 --------NYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFT 374 + + + +I+++K R + ++ + S + VK + Sbjct: 278 MWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPF-- 335 Query: 375 DDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFV-------SLSKSKNATAA 427 + N+I G E+D S F +Q K+ + S S+ ++ Sbjct: 336 NLTNNIPG----CEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391 Query: 428 CGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFI 487 + + K C+ +N + + S TDK N KK N + Sbjct: 392 SKFHLHENKLDCD---------NDNKPGIGHIFS-TDK-----NFHNDASTKKARNPEVV 436 Query: 488 LQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQN 547 + + +E++ E D++ K M + S KSL+ +L+ + S + Sbjct: 437 MVEMKEDQ-------EFDLQMTKNMNQ------NSDSGSTNNYKSLKPKLENLSSLPPDS 483 Query: 548 FHTHE--RERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEK 605 T E +L Q+ ++E+ L E +K ++ + +++E + N+ +L Sbjct: 484 DRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSG 543 Query: 606 TLK------RNEETLTKTITR-----YSKELNVLMDENTMLNSELQKEKQSMSRLE-TEM 653 TL +++ L + I R + + + +E + +++ E +E +E+ Sbjct: 544 TLTDGTTVGNDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEI 603 Query: 654 ESYRCRLAAALCDH------DQRQSSKRDLQL-AFQSTVNEWCHLQEDTNSHIQILSQQL 706 S C L+ ++ ++ R K L Q T HL + N+H L+ +L Sbjct: 604 ASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKL 663 Query: 707 SKAESTSSGLETELHYEREALKEKTL-------HIEHMQGVLSRTQRRLEDIEHMYQNDQ 759 + E+ S L+ EL ++ + L + ++ L + + + +Y D Sbjct: 664 KQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDS 723 Query: 760 PILE-------KYVRKQQSVEDGLFQLQSQ------NL-LYQQQCNDARKKADN------ 799 L K V +Q ++ L +L + NL L Q+ NDA+K+ Sbjct: 724 EQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARI 783 Query: 800 -QEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQC----------QYEK 848 Q++ + + Q + E +K+ +E + K L E +L+E K Sbjct: 784 LQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNK 843 Query: 849 EKEEREVVRRQLQREVDD------ALNKQLLLEAMLEISSERRINLEDEAQSLKKKL 899 +KE++ + +E +D LN++ L E +L+ S + NL E + L +L Sbjct: 844 QKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLN-NLTAENKILNSEL 899 Score = 35.0 bits (79), Expect = 0.32 Identities = 106/581 (18%), Positives = 237/581 (40%), Gaps = 108/581 (18%) Query: 258 EYKANKRR--KSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRN 315 + K N RR K L+ + DL + + ++ E +++++ + K++E++R Sbjct: 742 QLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARK 801 Query: 316 V--------HADDSDNYNDD------VDELIHKIKNRKPDNHQSPGKENGEFDRLARKTS 361 H + D +++D + L +I K N Q K + + + K Sbjct: 802 KMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKND 861 Query: 362 NEKSKVK-SQIYFTDDLNDISGSSEKTSEDDELPYSDDENFM-----LLIKQSGMECKDF 415 N + +K ++ T+ + SG + ++++ S+ EN L I+ C+ Sbjct: 862 NLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLA 921 Query: 416 VSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ---KVLSETDKTKSQSEH 472 ++ + A ++ Q+ E +++ KMK ++S LQ ++LSE + ++S+ Sbjct: 922 AAVRDCDQSQTARDLKLDFQRTRQEWVRLH-DKMKVDMSGLQAKNEILSEK-LSNAESKI 979 Query: 473 QNLQ----------GKKKLC--NLRFILQQQEEERIKAEELYEKDIEELK--IMEEQYRT 518 +LQ G++ L ++ L Q + ++ + E++Y+ + +LK I +++ Sbjct: 980 NSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVE 1039 Query: 519 QTEVKKQSKLTLKSLEVELKTVRSNSNQN--------FHTH------ERERD---LWQEN 561 + + QS+ L +++ ++NS + FH+ E E+ L ++N Sbjct: 1040 ERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKN 1099 Query: 562 HLMRDEIARLRLEIDTIKHQN----------QET----------ENKYFK------DIEI 595 + DE L+ +D + + QET EN+ + ++ Sbjct: 1100 KELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKA 1159 Query: 596 IKENNEDLEKTLKRNEETLTKTITRYSKEL---------NVLMDENTMLNSE-------- 638 I++ E L+K K+ ++ + + + + +L++E E Sbjct: 1160 IQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAIL 1219 Query: 639 -LQKE-----KQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQST-VNEWCHL 691 LQK+ +Q + E S + ++ + D + S + Q F T + + L Sbjct: 1220 TLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKEL 1279 Query: 692 QEDTNSHIQILSQQLSKAESTSSGLETELHYEREALKEKTL 732 + + LS +LS+ + + T+L E+E + ++L Sbjct: 1280 YLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTRSRSL 1320 Score = 30.8 bits (68), Expect = 6.0 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 7/62 (11%) Query: 17 TWRKN-------RDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRD 69 +W KN + P + VR +DLG +H+AA +GDV V + ++ RD Sbjct: 52 SWWKNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRD 111 Query: 70 KK 71 +K Sbjct: 112 RK 113 >gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo sapiens] Length = 498 Score = 383 bits (983), Expect = e-106 Identities = 224/463 (48%), Positives = 309/463 (66%), Gaps = 20/463 (4%) Query: 12 RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71 + M WR + D F+ P Y VR++DLG +H+AA G+V + ++LR +N RDKK Sbjct: 40 KNNMGAWR-DHDDSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKK 98 Query: 72 NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131 RTAL LACA+G VV+ L+ R+CQL++ DS+ RTALIKAVQCQE+ CA +LL+HG +P Sbjct: 99 KRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDP 158 Query: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191 N+ DMYGNTALHYA+ NE+ MA+ LL YGADIE++++ G T LLLAV+ +K++MV FL+ Sbjct: 159 NLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLI 218 Query: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251 KKK +L A+D FGRTALILA R GS S+V LLQ NIDVF QD+ G TAEDYAV+S Sbjct: 219 KKKANLNALDRFGRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSI 278 Query: 252 IRGMISEYKANKR-RKSLQNSNSEQDLEMTSEGEQERLEGCESSQ--------------- 295 I ++S+YK N+ S NSN EQDL++TSE E +RL+G E+SQ Sbjct: 279 ICQLLSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCD 338 Query: 296 PQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355 +VEE+M+K + + +S N+ D + N D L+ + K+RK +N Q P E E+ R Sbjct: 339 REVEEEMQKHGSNNVGLSENL-TDGAAAGNGD-GGLVPQRKSRKHENQQFPNTEIEEYHR 396 Query: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDF 415 K SNEK+KVKSQI+ D+L+DI+ SE SED +L +S+ E F LLI+Q M+ D Sbjct: 397 -PEKKSNEKNKVKSQIHSVDNLDDITWPSEIASEDYDLLFSNYETFTLLIEQLKMDFNDS 455 Query: 416 VSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQK 458 SLSK ++A + +E + + E+L V+ ++M+N + VLQK Sbjct: 456 ASLSKIQDAVISEEHLLELKNSHYEQLTVEVEQMENMVHVLQK 498 >gi|113413200 PREDICTED: similar to protein expressed in prostate, ovary, testis, and placenta 2 [Homo sapiens] Length = 1038 Score = 353 bits (906), Expect = 4e-97 Identities = 238/630 (37%), Positives = 351/630 (55%), Gaps = 90/630 (14%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR++DL +H+AA G V + ++LR D+N +DK+ RTAL LA A+ Sbjct: 87 DDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASAN 146 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G GVV L+ R+CQLN+ D++ RTAL KAVQCQE+ CA +LLEHG +PN+ D YGNT L Sbjct: 147 GNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTL 206 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L A+D Sbjct: 207 HYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDR 266 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ NIDV QD+SG TA +YAV+S I ++S+YK Sbjct: 267 YGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEK 326 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +R +G E+SQP +VEE+MKK Sbjct: 327 QMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHE 386 Query: 307 NKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLAR-------- 358 + + + N+ + D D LI + K+R P+N Q P E+ E+ R+ Sbjct: 387 SNNVGLLENLSNGVTAGNGD--DGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEK 444 Query: 359 ---KTSNEKSKVKSQIYFTDD------LNDISGSSEKTSEDDELPYSDD---ENFMLL-- 404 K S+E S + + T + +G EK S++ E+ D ENFM + Sbjct: 445 QMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEE 504 Query: 405 IKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETD 464 +K+ G F + + ATA G D R K+ Q+ +T+ Sbjct: 505 MKKHGSTHVGFPE-NLTNGATAGNG----DDGLIPPR--------KSRTPESQQ-FPDTE 550 Query: 465 KTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKK 524 + S+ QN +K+ C +++ I +E+ + ++++++E K Sbjct: 551 NEEYHSDEQN-DTQKQFC-------EEQNTGILHDEILIHEEKQIEVVE---------KM 593 Query: 525 QSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQE 584 S+L+L ++ERD EN ++R+EIA LRLE+DT+KHQ+Q Sbjct: 594 NSELSLSC-------------------KKERDFLHENSMLREEIAMLRLELDTMKHQSQL 634 Query: 585 TENKYFKDIEIIKENNEDLEKTLKRNEETL 614 + KY +DIE +K+ N++L K L+ NE T+ Sbjct: 635 RKKKYLEDIESVKKKNDNLLKALQLNELTM 664 >gi|88953571 PREDICTED: similar to protein expressed in prostate, ovary, testis, and placenta 2 isoform 2 [Homo sapiens] Length = 1075 Score = 351 bits (900), Expect = 2e-96 Identities = 237/630 (37%), Positives = 350/630 (55%), Gaps = 90/630 (14%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR++DL +H+AA G V + ++LR D+N +DK+ RTAL LA A+ Sbjct: 124 DDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASAN 183 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G GVV L+ R+CQLN+ D++ RTAL KAVQCQE+ CA +LLEHG +PN+ D YGNT L Sbjct: 184 GNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTL 243 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L A+D Sbjct: 244 HYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDR 303 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ NIDV QD+SG TA +YAV+S I ++S+YK Sbjct: 304 YGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEK 363 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +R +G E+SQP +VEE+MKK Sbjct: 364 QMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHE 423 Query: 307 NKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLAR-------- 358 + + + N+ + D D LI + K+R P+N Q P E+ E+ R+ Sbjct: 424 SNNVGLLENLSNGVTAGNGD--DGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEK 481 Query: 359 ---KTSNEKSKVKSQIYFTDD------LNDISGSSEKTSEDDELPYSDD---ENFMLL-- 404 K S+E S + + T + +G EK S++ E+ D ENFM + Sbjct: 482 QMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEE 541 Query: 405 IKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETD 464 +K+ G F + + ATA G D R K+ Q+ +T+ Sbjct: 542 MKKHGSTHVGFPE-NLTNGATAGNG----DDGLIPPR--------KSRTPESQQ-FPDTE 587 Query: 465 KTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKK 524 + S+ QN +K+ C +++ I +E+ + ++++++E K Sbjct: 588 NEEYHSDEQN-DTQKQFC-------EEQNTGILHDEILIHEEKQIEVVE---------KM 630 Query: 525 QSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQE 584 S+L+L ++E+D EN +R+EIA LRLE+DT+KHQ+Q Sbjct: 631 NSELSLSC-------------------KKEKDFLHENSTLREEIAMLRLELDTMKHQSQL 671 Query: 585 TENKYFKDIEIIKENNEDLEKTLKRNEETL 614 + KY +DIE +K+ N++L K L+ NE T+ Sbjct: 672 RKKKYLEDIESVKKKNDNLLKALQLNELTM 701 >gi|153791352 prostate, ovary, testis expressed protein on chromosome 2 [Homo sapiens] Length = 1075 Score = 348 bits (894), Expect = 1e-95 Identities = 235/632 (37%), Positives = 348/632 (55%), Gaps = 94/632 (14%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR +DL +H+AA G V + ++LR D+N +DK+ RTAL LA A+ Sbjct: 124 DDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASAN 183 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G VV L+ R+CQLN+ D++ RTALIKAVQCQE+ CA +LLEHG +PN+ D YGNT L Sbjct: 184 GNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTL 243 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L A+D Sbjct: 244 HYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDR 303 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ NIDV QD+SG TA +YAV+S I ++S+YK Sbjct: 304 YGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEK 363 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +R +G E+SQP +VEE+MKK Sbjct: 364 QMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHE 423 Query: 307 NKKMEVSRN----VHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLAR---- 358 + + + N V A + DN LI + K+R P+N Q P E+ E+ R+ Sbjct: 424 SNNVGLLENLTNGVTAGNGDN------GLIPQRKSRTPENQQFPDNESEEYHRICELLSD 477 Query: 359 -------KTSNEKSKVKSQIYFTDD------LNDISGSSEKTSEDDELPYSDD---ENFM 402 K S+E S + + T + +G EK S++ E+ D ENFM Sbjct: 478 YKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM 537 Query: 403 LLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSE 462 I++ V ++ A G + + +K + S + + Sbjct: 538 -AIEEMKKHRSTHVGFPENLTNGATAGNGDDG--------LIPPRKSRTPES---QQFPD 585 Query: 463 TDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEV 522 T+ + S+ QN +K+ C +++ I +E+ + ++++++E Sbjct: 586 TENEEYHSDEQN-DTQKQFC-------EEQNTGILHDEILIHEEKQIEVVE--------- 628 Query: 523 KKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQN 582 K S+L+L ++E+D+ EN +R+EIA LRLE+DT+KHQ+ Sbjct: 629 KMNSELSLSC-------------------KKEKDILHENSTLREEIAMLRLELDTMKHQS 669 Query: 583 QETENKYFKDIEIIKENNEDLEKTLKRNEETL 614 Q E KY +DIE +K+ N++L K L+ NE T+ Sbjct: 670 QLREKKYLEDIESVKKRNDNLLKALQLNELTM 701 >gi|134133226 protein expressed in prostate, ovary, testis, and placenta 2 [Homo sapiens] Length = 1075 Score = 348 bits (893), Expect = 1e-95 Identities = 239/634 (37%), Positives = 351/634 (55%), Gaps = 98/634 (15%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR +DL +H+AA G V + ++LR D+N +DK+ RTAL LA A+ Sbjct: 124 DDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASAN 183 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G VV L+ R+CQLN+ D++ RTALIKAVQCQE+ CA +LLEHG +PN+ D YGNT L Sbjct: 184 GNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTL 243 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L A+D Sbjct: 244 HYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDR 303 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ NIDV QD+SG TA +YAV+S I ++S+YK Sbjct: 304 YGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEK 363 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQ+L++TSE E +R +G E+SQP +VEE+MKK Sbjct: 364 QMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHE 423 Query: 307 NKKMEVSRN----VHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLAR---- 358 + + + N V A + DN LI + K+R P+N Q P E+ E+ R+ Sbjct: 424 SNNVGLLENLTNGVTAGNGDN------GLIPQRKSRTPENQQFPDNESEEYHRICELLSD 477 Query: 359 -------KTSNEKSKVKSQIYFTDD------LNDISGSSEKTSEDDELPYSDD---ENFM 402 K S+E S + + T + +G EK S++ E+ D ENFM Sbjct: 478 YKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM 537 Query: 403 LL--IKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVL 460 + +K+ G F + + ATA G D R K+ Q+ Sbjct: 538 AIEEMKKHGSTHVGFPE-NLTNGATAGNG----DDGLIPPR--------KSRTPESQQ-F 583 Query: 461 SETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQT 520 +T+ + S+ QN +K+ C +++ I +E+ + ++++++E Sbjct: 584 PDTENEEYHSDEQN-DTQKQFC-------EEQNTGILHDEILIHEEKQIEVVE------- 628 Query: 521 EVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKH 580 K S+L+L ++E+D+ EN +R+EIA LRLE+DT+KH Sbjct: 629 --KMNSELSLSC-------------------KKEKDVLHENSTLREEIAMLRLELDTMKH 667 Query: 581 QNQETENKYFKDIEIIKENNEDLEKTLKRNEETL 614 Q+Q E KY +DIE +K+ N++L K L+ NE T+ Sbjct: 668 QSQLREKKYLEDIESVKKKNDNLLKALQLNELTM 701 >gi|115495445 ankyrin repeat domain 30A [Homo sapiens] Length = 1341 Score = 330 bits (845), Expect = 5e-90 Identities = 199/448 (44%), Positives = 283/448 (63%), Gaps = 14/448 (3%) Query: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEH 472 +D SLSK + +C R+ E QK +CE+ K ++MK VL+K LSE + KSQ E+ Sbjct: 900 EDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLEN 959 Query: 473 QNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKS 532 Q ++ +++LC++R L Q+EE+R A+ L EK EEL +EEQ+R + EVK+Q + L+ Sbjct: 960 QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRI 1019 Query: 533 LEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKD 592 ++ELK+V SN NQ HTHE E L EN +++ EIA L+LEI T+KHQ QE ENKYF+D Sbjct: 1020 QDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFED 1079 Query: 593 IEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETE 652 I+I+KE N +L+ TLK EE+LTK ++YS +L VL+ ENTML S+L KEKQ LE E Sbjct: 1080 IKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAE 1138 Query: 653 MESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWC---HLQEDTNSHI---QILSQQL 706 +ES+ RLA+A+ DHDQ +S++ + AF + C + D +S I ++L Q L Sbjct: 1139 IESHHPRLASAVQDHDQIVTSRKSQEPAFH-IAGDACLQRKMNVDVSSTIYNNEVLHQPL 1197 Query: 707 SKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYV 766 S+A+ S L+ L+Y +AL+E TL EH Q TQ ++++ EHMYQN+Q + K+ Sbjct: 1198 SEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHT 1257 Query: 767 RKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLE 826 +Q+S++ LFQLQS+N+ QQQ A KKADN+ K I+I K+Q L+ Sbjct: 1258 EQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF----LERKMQHHL--LK 1311 Query: 827 ENNKGLMKECTLLKERQCQYEKEKEERE 854 E N+ + LK R QYEKEK E E Sbjct: 1312 EKNEEIFNYNNHLKNRIYQYEKEKAETE 1339 Score = 189 bits (481), Expect = 8e-48 Identities = 107/239 (44%), Positives = 149/239 (62%), Gaps = 5/239 (2%) Query: 64 DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASI 123 +LN +D + RTAL AC +G VV LV RKCQL++ D E+RT L+KA+QC +E CA+I Sbjct: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68 Query: 124 LLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKK 183 L++ GA+ N+ D+YGNTALHYA+ +E +S+ KLL++GA IE ++ T LLL++ ++ Sbjct: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128 Query: 184 EQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDY 243 EQ+V FLL K + A++ + TAL+LA +GS+ +V LLQ N+DVF DI G TAE Y Sbjct: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188 Query: 244 AVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKM 302 AV F I I EY K K+ QN+N E TS G + P E + Sbjct: 189 AVTCGFHHIHEQIMEY-IRKLSKNHQNTNPEG----TSAGTPDEAAPLAERTPDTAESL 242 >gi|222537750 ankyrin repeat domain 30B [Homo sapiens] Length = 1392 Score = 314 bits (805), Expect = 2e-85 Identities = 222/600 (37%), Positives = 334/600 (55%), Gaps = 55/600 (9%) Query: 269 QNSNSEQDLEMTS-EGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDD 327 Q++ E+D +T+ EG + + G + + E+ + + KM S +D+ + +D Sbjct: 817 QSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDS 876 Query: 328 VDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKT 387 + +N + + KE KT+N K I S EK Sbjct: 877 EIISVSDTQNYECLPEATYQKEI--------KTTNGK---------------IEESPEKP 913 Query: 388 SEDDELPYSDDENFMLLIKQSGMECK-------DFVSLSKSKNATAACGRSIEDQKCYCE 440 S + P ++ +N + G+E K D +LSK +A +C R E +K CE Sbjct: 914 SHFE--PATEMQNS---VPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCE 968 Query: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 ++ K ++ KN VLQK LSE + KSQ E+Q + +++LC++R L Q+EE+R + Sbjct: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028 Query: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 L EK E EQ R + EVK+Q + TL+ ++ELK+V SN NQ HTHE E DL+ E Sbjct: 1029 LKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083 Query: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 N +++ EIA L+LE+ T+KHQ+Q ENKYF+DI+I++E N +L+ TLK ++T+TK ++ Sbjct: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143 Query: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Y ++L VL ENTML S+L KEKQ LETE+ES+ RLA+AL DHDQ +S+++ +LA Sbjct: 1144 YREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202 Query: 681 FQSTVNEWCH--LQEDTNSHI---QILSQQLSKAESTSSGLETELHYEREALKEKTLHIE 735 F S + + D ++ I ++L Q L +A+ S + L+Y + L+E L E Sbjct: 1203 FHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSE 1262 Query: 736 HMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARK 795 H Q TQ +++ EHMYQN+Q ++K+ +Q+S+E LFQL+S+N +QQ A K Sbjct: 1263 HAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHK 1322 Query: 796 KADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEEREV 855 K N+ K INIQ K+Q R L E N+ + LKER QYEKEK EREV Sbjct: 1323 KV-NKSKVTINIQF----PEMKMQ---RHLNEKNEEVFNYGNHLKERIDQYEKEKAEREV 1374 Score = 197 bits (502), Expect = 3e-50 Identities = 118/266 (44%), Positives = 158/266 (59%), Gaps = 6/266 (2%) Query: 38 DLGMIHKAAIAGDVNKVME-SILLRLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKC 96 DLG IH AA G V K+ + ++ + +LN RD K RTAL AC +G VV LV RKC Sbjct: 38 DLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKC 97 Query: 97 QLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARK 156 QLN+ D E RT L+KA+QC+ E CA+IL++ GA+ N D+YGNTALHYA+ +EN+ M Sbjct: 98 QLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVAT 157 Query: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGS 216 LL+YGA IE +++ T LLLA+ ++ +Q V FLL K + A + TAL+LA GS Sbjct: 158 LLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGS 217 Query: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQD 276 + +V LLQ N+DVF +DI G TAE YA A I + E+ K K+ QN+N E Sbjct: 218 SEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEH-IRKLPKNPQNTNPEG- 275 Query: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302 TS G + P E + Sbjct: 276 ---TSTGTPDEAAPLAERTPDTAESL 298 >gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo sapiens] Length = 452 Score = 310 bits (795), Expect = 3e-84 Identities = 195/463 (42%), Positives = 277/463 (59%), Gaps = 66/463 (14%) Query: 12 RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71 + M WR + D F+ P Y VR++DLG +H+AA G+V + ++LR +N RDKK Sbjct: 40 KNNMGAWR-DHDDSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKK 98 Query: 72 NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131 RTAL LACA+G VV+ L+ R+CQL++ DS+ RTALIKAVQCQE+ CA +LL+HG +P Sbjct: 99 KRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDP 158 Query: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191 N+ DMYGNTALHYA+ NE+ MA+ LL YGADIE++++ G T LLLAV+ +K++MV FL+ Sbjct: 159 NLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLI 218 Query: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251 KKK +L A+D FGR CQ Sbjct: 219 KKKANLNALDRFGR-------------------------ICQ------------------ 235 Query: 252 IRGMISEYKANKR-RKSLQNSNSEQDLEMTSEGEQERLEGCESSQ--------------- 295 ++S+YK N+ S NSN EQDL++TSE E +RL+G E+SQ Sbjct: 236 ---LLSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCD 292 Query: 296 PQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355 +VEE+M+K + + +S N+ D + N D L+ + K+RK +N Q P E E+ R Sbjct: 293 REVEEEMQKHGSNNVGLSENL-TDGAAAGNGD-GGLVPQRKSRKHENQQFPNTEIEEYHR 350 Query: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDF 415 K SNEK+KVKSQI+ D+L+DI+ SE SED +L +S+ E F LLI+Q M+ D Sbjct: 351 -PEKKSNEKNKVKSQIHSVDNLDDITWPSEIASEDYDLLFSNYETFTLLIEQLKMDFNDS 409 Query: 416 VSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQK 458 SLSK ++A + +E + + E+L V+ ++M+N + VLQK Sbjct: 410 ASLSKIQDAVISEEHLLELKNSHYEQLTVEVEQMENMVHVLQK 452 >gi|52856430 protein expressed in prostate, ovary, testis, and placenta 15 [Homo sapiens] Length = 581 Score = 303 bits (777), Expect = 4e-82 Identities = 195/477 (40%), Positives = 277/477 (58%), Gaps = 45/477 (9%) Query: 12 RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71 + + TW + D F P Y VR++DL +H+AA G V + ++LR D+N RDK+ Sbjct: 114 KSNVGTWG-DYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQ 172 Query: 72 NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131 RTAL LA A+G VV L+ R+CQLN+ D++ RTALIKAVQCQE+ C +LLEHGA+ Sbjct: 173 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADG 232 Query: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191 N++D YGNTALHYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+ Sbjct: 233 NIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLI 292 Query: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251 KKK +L A+D +GRTALILA GS S+V LL+ N+DV QD+SG TA +YAV+S Sbjct: 293 KKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHV 352 Query: 252 IRGMISEYKANKRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP-------------- 296 I ++S+YK + K S +NSN EQDL++TSE E +RL+ E+SQP Sbjct: 353 ICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCD 412 Query: 297 -QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355 +VEE++KK + + + N+ S D D LI + K+RKP+N Q P EN E Sbjct: 413 REVEEEIKKHGSNPVGLPENLTNGASAGNGD--DGLIPQRKSRKPENQQFPDTENEE--- 467 Query: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMEC 412 Y +D+ ND + ++ SE+ S DE N I+ + E Sbjct: 468 ----------------YHSDEQND---TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEM 508 Query: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQ 469 +SLS K S+ ++ RL++ K +N + K+L E + K + Sbjct: 509 NSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRE-NKILEEIESVKEK 564 Score = 101 bits (251), Expect = 4e-21 Identities = 119/464 (25%), Positives = 200/464 (43%), Gaps = 58/464 (12%) Query: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222 D+ R + T+L LA ++V LL ++ L +DN RTALI A + V Sbjct: 165 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 224 Query: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282 LL+H D QD G TA YA+ ++ + + + Y A D+E ++ Sbjct: 225 LLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 270 Query: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341 G L G + QV K + + + + D Y L + Sbjct: 271 CGLTPLLLGVHEQKQQVV---------KFLIKKKANLNALDRYGRTALILAVCCGSASIV 321 Query: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395 N + L+ +T+ E + + L+D + SSE ++ + +L Sbjct: 322 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 381 Query: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454 S++E+ L + ++ K +S+ C R +E++ +K +N Sbjct: 382 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 427 Query: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513 L + L+ + + Q K +K N +F + EE E++ + ++ E Sbjct: 428 GLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSD-----EQNDTQKQLSE 482 Query: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573 EQ T + + LT K ++E+ NS + +H++E DL +EN ++R+EIA LRL Sbjct: 483 EQ---NTGISQDEILTNKQKQIEVAEKEMNSKLSL-SHKKEEDLLRENSMLREEIAMLRL 538 Query: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617 E+D KHQNQ ENK ++IE +KE L K ++ NEE LTKT Sbjct: 539 ELDETKHQNQLRENKILEEIESVKEK---LLKAIQLNEEALTKT 579 >gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo sapiens] Length = 544 Score = 301 bits (772), Expect = 1e-81 Identities = 194/477 (40%), Positives = 277/477 (58%), Gaps = 45/477 (9%) Query: 12 RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71 + + TW + D F P Y VR++DL +H+AA G V + ++LR D+N RDK+ Sbjct: 77 KSNVGTWG-DYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQ 135 Query: 72 NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131 RTAL LA A+G VV L+ R+CQLN+ D++ RTALIKAVQCQE+ C +LLEHGA+ Sbjct: 136 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADG 195 Query: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191 N++D YGNTALHYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+++V FL+ Sbjct: 196 NIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLI 255 Query: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251 KKK +L A+D +GRTALILA GS S+V LL+ N+DV QD+SG TA +YAV+S Sbjct: 256 KKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHV 315 Query: 252 IRGMISEYKANKRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP-------------- 296 I ++S+YK + K S +NSN EQDL++TSE E +RL+ E+SQP Sbjct: 316 ICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCD 375 Query: 297 -QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355 +VEE++KK + + + N+ S D D LI + K+RKP+N Q P EN E Sbjct: 376 REVEEEIKKHGSNPVGLPENLTNGASAGNGD--DGLIPQRKSRKPENQQFPDTENEE--- 430 Query: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMEC 412 Y +D+ ND + ++ SE+ S DE N I+ + E Sbjct: 431 ----------------YHSDEQND---TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEM 471 Query: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQ 469 +SLS K S+ ++ RL++ K +N + K+L E + K + Sbjct: 472 NSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRE-NKILEEIESVKEK 527 Score = 103 bits (256), Expect = 1e-21 Identities = 119/464 (25%), Positives = 202/464 (43%), Gaps = 58/464 (12%) Query: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222 D+ R + T+L LA ++V LL ++ L +DN RTALI A + V Sbjct: 128 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 187 Query: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282 LL+H D QD G TA YA+ ++ + + + Y A D+E ++ Sbjct: 188 LLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 233 Query: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341 G L G + +V K + + + + D Y L + Sbjct: 234 CGLTPLLLGVHEQKQEVV---------KFLIKKKANLNALDRYGRTALILAVCCGSASIV 284 Query: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395 N + L+ +T+ E + + L+D + SSE ++ + +L Sbjct: 285 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 344 Query: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454 S++E+ L + ++ K +S+ C R +E++ +K +N Sbjct: 345 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 390 Query: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513 L + L+ + + Q K +K N +F + EE E++ + ++ E Sbjct: 391 GLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSD-----EQNDTQKQLSE 445 Query: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573 EQ T + + LT K ++E+ NS + +H++E DL +EN ++R+EIA+LRL Sbjct: 446 EQ---NTGISQDEILTNKQKQIEVAEKEMNSELSL-SHKKEEDLLRENSMLREEIAKLRL 501 Query: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617 E+D KHQNQ ENK ++IE +KE L KT++ NEE LTKT Sbjct: 502 ELDETKHQNQLRENKILEEIESVKEK---LLKTIQLNEEALTKT 542 >gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2 [Homo sapiens] Length = 551 Score = 299 bits (766), Expect = 7e-81 Identities = 189/468 (40%), Positives = 272/468 (58%), Gaps = 44/468 (9%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR++DL +H+AA G V + ++LR D+N RDK+ RTAL LA A+ Sbjct: 91 DHSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASAN 150 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G VV L+ R+CQLN+ D++ RTALIKA+QCQE+ C +LLEHGA+ N+ D YGNTAL Sbjct: 151 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTAL 210 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L +D Sbjct: 211 HYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDR 270 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ N+DV QD+SG TA +YAV+S I ++S+YK Sbjct: 271 YGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEK 330 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +RL+ E+SQP +VEE++KK Sbjct: 331 QMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHG 390 Query: 307 NKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSK 366 + + + N+ S D D LI + ++RKP+N Q P EN E Sbjct: 391 SNPVGLPENLTNGASAGNGD--DGLIPQRRSRKPENQQFPDTENEE-------------- 434 Query: 367 VKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMECKDFVSLSKSKN 423 Y +D+ ND + ++ SE+ S DE N I+ + + +SLS K Sbjct: 435 -----YHSDEQND---TRKQLSEEQNTGISQDEILTNKQKQIEVAEQKMNSELSLSHKKE 486 Query: 424 ATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSE 471 S+ ++ RL++ K +N + K+L E + K +++ Sbjct: 487 EDLLRENSVLQEEIAVLRLELDETKHQNQLRE-NKILEEIESVKEKTD 533 Score = 99.8 bits (247), Expect = 1e-20 Identities = 115/464 (24%), Positives = 201/464 (43%), Gaps = 55/464 (11%) Query: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222 D+ R ++ T+L LA ++V LL ++ L +DN RTALI A + V Sbjct: 132 DMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLM 191 Query: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282 LL+H D D G TA YA+ ++ + + + Y A D+E ++ Sbjct: 192 LLEHGADRNIPDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 237 Query: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341 G L G + QV K + + + + D Y L + Sbjct: 238 CGLTPLLLGVHEQKQQVV---------KFLIKKKANLNVLDRYGRTALILAVCCGSASIV 288 Query: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395 N + L+ +T+ E + + L+D + SSE ++ + +L Sbjct: 289 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 348 Query: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454 S++E+ L + ++ K +S+ C R +E++ +K +N Sbjct: 349 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 394 Query: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513 L + L+ + + Q + +K N +F + EE E++ ++ E Sbjct: 395 GLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSD-----EQNDTRKQLSE 449 Query: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573 EQ T + + LT K ++E+ + NS + +H++E DL +EN ++++EIA LRL Sbjct: 450 EQ---NTGISQDEILTNKQKQIEVAEQKMNSELSL-SHKKEEDLLRENSVLQEEIAVLRL 505 Query: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617 E+D KHQNQ ENK ++IE +KE + L + ++ NEE LTKT Sbjct: 506 ELDETKHQNQLRENKILEEIESVKEKTDKLLRAMQLNEEALTKT 549 >gi|239747114 PREDICTED: hypothetical protein XP_002343914 isoform 1 [Homo sapiens] Length = 584 Score = 299 bits (766), Expect = 7e-81 Identities = 189/468 (40%), Positives = 272/468 (58%), Gaps = 44/468 (9%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR++DL +H+AA G V + ++LR D+N RDK+ RTAL LA A+ Sbjct: 124 DHSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASAN 183 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G VV L+ R+CQLN+ D++ RTALIKA+QCQE+ C +LLEHGA+ N+ D YGNTAL Sbjct: 184 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTAL 243 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L +D Sbjct: 244 HYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDR 303 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ N+DV QD+SG TA +YAV+S I ++S+YK Sbjct: 304 YGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEK 363 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +RL+ E+SQP +VEE++KK Sbjct: 364 QMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHG 423 Query: 307 NKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSK 366 + + + N+ S D D LI + ++RKP+N Q P EN E Sbjct: 424 SNPVGLPENLTNGASAGNGD--DGLIPQRRSRKPENQQFPDTENEE-------------- 467 Query: 367 VKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMECKDFVSLSKSKN 423 Y +D+ ND + ++ SE+ S DE N I+ + + +SLS K Sbjct: 468 -----YHSDEQND---TRKQLSEEQNTGISQDEILTNKQKQIEVAEQKMNSELSLSHKKE 519 Query: 424 ATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSE 471 S+ ++ RL++ K +N + K+L E + K +++ Sbjct: 520 EDLLRENSVLQEEIAVLRLELDETKHQNQLRE-NKILEEIESVKEKTD 566 Score = 99.8 bits (247), Expect = 1e-20 Identities = 115/464 (24%), Positives = 201/464 (43%), Gaps = 55/464 (11%) Query: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222 D+ R ++ T+L LA ++V LL ++ L +DN RTALI A + V Sbjct: 165 DMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLM 224 Query: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282 LL+H D D G TA YA+ ++ + + + Y A D+E ++ Sbjct: 225 LLEHGADRNIPDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 270 Query: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341 G L G + QV K + + + + D Y L + Sbjct: 271 CGLTPLLLGVHEQKQQVV---------KFLIKKKANLNVLDRYGRTALILAVCCGSASIV 321 Query: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395 N + L+ +T+ E + + L+D + SSE ++ + +L Sbjct: 322 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 381 Query: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454 S++E+ L + ++ K +S+ C R +E++ +K +N Sbjct: 382 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 427 Query: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513 L + L+ + + Q + +K N +F + EE E++ ++ E Sbjct: 428 GLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSD-----EQNDTRKQLSE 482 Query: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573 EQ T + + LT K ++E+ + NS + +H++E DL +EN ++++EIA LRL Sbjct: 483 EQ---NTGISQDEILTNKQKQIEVAEQKMNSELSL-SHKKEEDLLRENSVLQEEIAVLRL 538 Query: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617 E+D KHQNQ ENK ++IE +KE + L + ++ NEE LTKT Sbjct: 539 ELDETKHQNQLRENKILEEIESVKEKTDKLLRAMQLNEEALTKT 582 >gi|153792284 pote protein [Homo sapiens] Length = 584 Score = 299 bits (765), Expect = 9e-81 Identities = 188/468 (40%), Positives = 272/468 (58%), Gaps = 44/468 (9%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y +R++DL +H+AA G V + ++LR D+N RDK+ RTAL LA A+ Sbjct: 124 DHSAFMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASAN 183 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G VV L+ R+CQLN+ D++ RTALIKA+QCQE+ C +LLEHGA+ N+ D YGNTAL Sbjct: 184 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTAL 243 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYAI NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L +D Sbjct: 244 HYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDR 303 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ N+DV QD+SG TA +YAV+S I ++S+YK Sbjct: 304 YGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEK 363 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +RL+ E+SQP +VEE++KK Sbjct: 364 QMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHG 423 Query: 307 NKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSK 366 + + + N+ S D D LI + ++RKP+N Q P EN E Sbjct: 424 SNPVGLPENLTNGASAGNGD--DGLIPQRRSRKPENQQFPDTENEE-------------- 467 Query: 367 VKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMECKDFVSLSKSKN 423 Y +D+ ND + ++ SE+ S DE N I+ + + +SLS K Sbjct: 468 -----YHSDEQND---TRKQLSEEQNTGISQDEILTNKQKQIEVAEQKMNSELSLSHKKE 519 Query: 424 ATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSE 471 S+ ++ RL++ K +N + K+L E + K +++ Sbjct: 520 EDLLRENSVLQEEIAMLRLELDETKHQNQLRE-NKILEEIESVKEKTD 566 Score = 100 bits (249), Expect = 6e-21 Identities = 115/464 (24%), Positives = 201/464 (43%), Gaps = 55/464 (11%) Query: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222 D+ R ++ T+L LA ++V LL ++ L +DN RTALI A + V Sbjct: 165 DMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLM 224 Query: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282 LL+H D D G TA YA+ ++ + + + Y A D+E ++ Sbjct: 225 LLEHGADRNIPDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 270 Query: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341 G L G + QV K + + + + D Y L + Sbjct: 271 CGLTPLLLGVHEQKQQVV---------KFLIKKKANLNVLDRYGRTALILAVCCGSASIV 321 Query: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395 N + L+ +T+ E + + L+D + SSE ++ + +L Sbjct: 322 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 381 Query: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454 S++E+ L + ++ K +S+ C R +E++ +K +N Sbjct: 382 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 427 Query: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513 L + L+ + + Q + +K N +F + EE E++ ++ E Sbjct: 428 GLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSD-----EQNDTRKQLSE 482 Query: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573 EQ T + + LT K ++E+ + NS + +H++E DL +EN ++++EIA LRL Sbjct: 483 EQ---NTGISQDEILTNKQKQIEVAEQKMNSELSL-SHKKEEDLLRENSVLQEEIAMLRL 538 Query: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617 E+D KHQNQ ENK ++IE +KE + L + ++ NEE LTKT Sbjct: 539 ELDETKHQNQLRENKILEEIESVKEKTDKLLRAMQLNEEALTKT 582 >gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens] Length = 542 Score = 295 bits (754), Expect = 2e-79 Identities = 171/402 (42%), Positives = 247/402 (61%), Gaps = 24/402 (5%) Query: 23 DKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAH 82 D F P Y VR++DL +H+AA G V + ++LR D+N RDK+ RTAL LA A+ Sbjct: 124 DDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASAN 183 Query: 83 GRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTAL 142 G VV L+ R+CQLN+ D++ RTALIKAVQCQE+ C +LLEHGA+ N+ D YGNT L Sbjct: 184 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADQNIPDEYGNTTL 243 Query: 143 HYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDN 202 HYA+ NE+ MA+ LL YGADIE++++ G T LLL V+ +K+Q+V FL+KKK +L A+D Sbjct: 244 HYAVHNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDR 303 Query: 203 FGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN 262 +GRTALILA GS S+V LL+ N+DV QD+SG TA +YAV+S I ++S+YK Sbjct: 304 YGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEK 363 Query: 263 KRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP---------------QVEEKMKKCR 306 + K S +NSN EQDL++TSE E +RL+ E+SQP +VEE++KK Sbjct: 364 QMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHG 423 Query: 307 NKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEF------DRLARKT 360 + + + N+ S D D LI + ++RKP+N Q P EN E+ D + + Sbjct: 424 SNPVGLPENLTNGASAGNGD--DGLIPQRRSRKPENQQFPDTENEEYHSDEQNDTRKQLS 481 Query: 361 SNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFM 402 + + + T+ I + +K + + L + +E+ + Sbjct: 482 EEQNTGISQDEILTNKQKQIEVAEKKMNSELSLSHKKEEDLL 523 Score = 52.8 bits (125), Expect = 1e-06 Identities = 91/418 (21%), Positives = 167/418 (39%), Gaps = 55/418 (13%) Query: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222 D+ R + T+L LA ++V LL ++ L +DN RTALI A + V Sbjct: 165 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 224 Query: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282 LL+H D D G T YAV ++ + + + Y A D+E ++ Sbjct: 225 LLEHGADQNIPDEYGNTTLHYAVHNEDKLMAKALLLYGA--------------DIESKNK 270 Query: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341 G L G + QV K + + + + D Y L + Sbjct: 271 CGLTPLLLGVHEQKQQVV---------KFLIKKKANLNALDRYGRTALILAVCCGSASIV 321 Query: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395 N + L+ +T+ E + + L+D + SSE ++ + +L Sbjct: 322 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 381 Query: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454 S++E+ L + ++ K +S+ C R +E++ +K +N Sbjct: 382 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 427 Query: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513 L + L+ + + Q + +K N +F + EE E++ ++ E Sbjct: 428 GLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSD-----EQNDTRKQLSE 482 Query: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARL 571 EQ T + + LT K ++E+ + NS + +H++E DL +EN ++++EIA L Sbjct: 483 EQ---NTGISQDEILTNKQKQIEVAEKKMNSELSL-SHKKEEDLLRENSMLQEEIAML 536 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.127 0.347 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,185,845 Number of Sequences: 37866 Number of extensions: 1383497 Number of successful extensions: 17059 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 548 Number of HSP's successfully gapped in prelim test: 1000 Number of HSP's that attempted gapping in prelim test: 6773 Number of HSP's gapped (non-prelim): 6003 length of query: 917 length of database: 18,247,518 effective HSP length: 111 effective length of query: 806 effective length of database: 14,044,392 effective search space: 11319779952 effective search space used: 11319779952 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.