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Search of human proteins with 11968003
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens]
(392 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens] 791 0.0
gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens] 424 e-119
gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens] 422 e-118
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 70 3e-12
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 58 1e-08
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 58 1e-08
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 57 2e-08
gi|19743569 TRAF interacting protein TANK isoform a [Homo sapiens] 57 4e-08
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 53 4e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 50 3e-06
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 48 1e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 48 1e-05
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 48 2e-05
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 48 2e-05
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 48 2e-05
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 48 2e-05
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 48 2e-05
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 48 2e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 48 2e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 48 2e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 47 2e-05
gi|224451082 cytospin A [Homo sapiens] 47 3e-05
gi|224451080 cytospin A [Homo sapiens] 47 3e-05
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 47 3e-05
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 47 3e-05
gi|38044112 restin isoform b [Homo sapiens] 47 4e-05
gi|4506751 restin isoform a [Homo sapiens] 47 4e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 46 5e-05
gi|4758648 kinesin family member 5B [Homo sapiens] 46 7e-05
gi|153945715 myosin VC [Homo sapiens] 46 7e-05
>gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens]
Length = 392
Score = 791 bits (2044), Expect = 0.0
Identities = 392/392 (100%), Positives = 392/392 (100%)
Query: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
Query: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ 240
KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ 240
Query: 241 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS 300
AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS
Sbjct: 241 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS 300
Query: 301 SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET 360
SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET
Sbjct: 301 SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET 360
Query: 361 AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN 392
AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN
Sbjct: 361 AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN 392
>gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens]
Length = 243
Score = 424 bits (1091), Expect = e-119
Identities = 216/224 (96%), Positives = 218/224 (97%)
Query: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
Query: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYW 224
KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS ++ W
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAW 224
>gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens]
Length = 232
Score = 422 bits (1085), Expect = e-118
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
Query: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS 215
KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS 215
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 70.1 bits (170), Expect = 3e-12
Identities = 82/330 (24%), Positives = 136/330 (41%), Gaps = 91/330 (27%)
Query: 1 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE 56
M+++ EDDI IL E D+ S+ GD ASHFAL+TAY DIK+RL E
Sbjct: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 59
Query: 57 KENSLLKKRIRFLEEK--LIARFEEE---------------------------------T 81
+EN+ L++R++ E K LI+ F EE
Sbjct: 60 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 119
Query: 82 SSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK-VLNEQLQSKEVELLQLRT 140
+ EQ+ + AY ++C+++ +L+++L +M L+ + + Q ++ + LQ
Sbjct: 120 NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQ--- 176
Query: 141 EVETQQVMRNLNPP------------------------SSNWEVEKLS-CDLKIHGLEQE 175
NL+PP + W S DL+ LE+
Sbjct: 177 ----DAAFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEA 232
Query: 176 LEL--------------MRKECSDLKIELQKAKQTDPYQ-EDNLKSRDL---QKLSISSD 217
LE ++ EC L+ EL++ ++T N RD+ +++
Sbjct: 233 LEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQV 292
Query: 218 NMQHAYWELKREMSNLHLVTQVQAELLRKL 247
N+ AY EL E+ L ++ +Q +LR L
Sbjct: 293 NLALAYTELTEELGRLRELSSLQGRILRTL 322
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 58.2 bits (139), Expect = 1e-08
Identities = 60/227 (26%), Positives = 113/227 (49%), Gaps = 24/227 (10%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE---EKLIARFEEETSSVGRE--QVNKAYHAYREVC 100
E+++ L EKEN LL+K+I L+ EK+ A E+E S + RE ++ K +++ +
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLT 686
Query: 101 IDRDNLK---SKLDKMNKD---NSESLKVLNEQLQSKEVELLQLRTEVETQ----QVMRN 150
++L+ S+LD+ N + N ESLK + ++ ++E +L +E E ++++
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746
Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
+ EV D++ L++ LE K+ L+ ELQ D E+ ++L+
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-----DLEMENQTLQKNLE 801
Query: 211 KLSISSDNMQHAYWE---LKREMSNLHLVTQVQAELLRKLKTSTAIK 254
+L ISS ++ E L++E S L + + ++L+ IK
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/281 (24%), Positives = 119/281 (42%), Gaps = 58/281 (20%)
Query: 6 EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
E I IL E H TV+ + S + A R+KD EKEN +L +
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEA--------------RVKDIEKENKILHES 595
Query: 66 IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNS------E 119
I+ KL ++ E E + Q+ K Y+E + L+++L + K+N
Sbjct: 596 IKETSSKL-SKIEFE-----KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 120 SLKVLNEQLQSKEVELLQLRTE----VETQQVMRNLNPPSSNWE---------------- 159
+LK+ E++++ E E +L E +T +NL + E
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709
Query: 160 VEKLSC--------DLKIHGLEQELELMRKECSDLKIELQKAKQTD-PYQEDNLKSRDLQ 210
VE L C L+ LE E E ++K LK +K ++ + YQ +++++ LQ
Sbjct: 710 VESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ 769
Query: 211 KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTST 251
K + +N +L+ E+ +L + Q + L +LK S+
Sbjct: 770 K---TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/201 (25%), Positives = 97/201 (48%), Gaps = 21/201 (10%)
Query: 53 KDSEKENSLLKKRIRFLEE---KLIARFEEETSSVGREQVNKAYHAYREVC-IDRDNLKS 108
KD KE + L+K I L E + I E+E E +N+ + R+ I +
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQEN-----EHLNQTVSSLRQRSQISAEARVK 583
Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK 168
++K NK ES+K + +L E E Q++ E+E + E+L +L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK--------EKGERAEELENEL- 634
Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKR 228
H LE+E EL++K+ ++LKI +K + + QE++ R+ +KL + D+ ++ ++L+
Sbjct: 635 -HHLEKENELLQKKITNLKITCEKIEALE--QENSELERENRKLKKTLDSFKNLTFQLES 691
Query: 229 EMSNLHLVTQVQAELLRKLKT 249
+ + EL R +++
Sbjct: 692 LEKENSQLDEENLELRRNVES 712
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 23/187 (12%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS-VGREQVNKAYHAYREVCIDRD 104
E+ ++L D ++E ++ ++ L+++ + + S+ + R++++ A RE + D
Sbjct: 268 EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVD 323
Query: 105 NLKSKLDKMNK--DNSESLKVLNEQLQSKEVELLQLRTEVETQ-QVMRNLNPPSSNWEVE 161
L+S++ + + + E K E+L+ LL+ +T +E Q + R + E E
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQH 221
L K+H +E E ++ RK+ +L E+N+ QK S+ D H
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEEL-------------MEENMTLEMAQKQSM--DESLH 428
Query: 222 AYWELKR 228
WEL++
Sbjct: 429 LGWELEQ 435
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/222 (23%), Positives = 100/222 (45%), Gaps = 37/222 (16%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQ-----VNKAYHAYREV 99
Y++ RLK+ EKEN L KR + L+ E+ S + Q + K H ++
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Query: 100 CIDRDNLKSKLDKMNKDNSESLKVLNEQLQS----------KEVELLQLRTEVET---QQ 146
++++ L D+ + D+S K+L +L+S +++ L+ R E T QQ
Sbjct: 936 GLNKERLLH--DEQSTDDSR-YKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQ 992
Query: 147 VMRNLNPPSSNWEVEKLSCDLK--------IHGLEQELELMRKECS-------DLKIELQ 191
+ + L N+E K D + I G + + E +E + D IE++
Sbjct: 993 LRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVE 1052
Query: 192 KAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNL 233
+ T ++ LK++ L++L ++N+Q L+R+ +L
Sbjct: 1053 RNNATLQAEKQALKTQ-LKQLETQNNNLQAQILALQRQTVSL 1093
Score = 38.1 bits (87), Expect = 0.014
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 38/221 (17%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE--EKLIARFEEETSSVGREQVNKAYHAYREVCIDR 103
+ ++ L+D E EN L+K + L+ K + + E+E S+ +E +++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ----------LEK 829
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKL 163
D K +L+K NK + ++ + L+ V++ L E +T S + K
Sbjct: 830 D--KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL---------SKEIGIYKE 878
Query: 164 SCDLKIHGLEQE-LELMRKECSDLK--------IELQKAKQTDPYQEDNLKSRDLQKLSI 214
SC +++ LE+E EL+++ D+K + +K K + + +L+K+ +
Sbjct: 879 SC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGL 937
Query: 215 SSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKK 255
+ + + H E + S L ++++L LK S IK+
Sbjct: 938 NKERLLHD--EQSTDDSRYKL---LESKLESTLKKSLEIKE 973
Score = 37.0 bits (84), Expect = 0.031
Identities = 51/246 (20%), Positives = 108/246 (43%), Gaps = 28/246 (11%)
Query: 8 DICILNHEKA---HKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE-KENSLLK 63
D I +HEK H+R S+ ++ H L +A+++++ +D E + N LLK
Sbjct: 1154 DSLIKDHEKLELLHERQASEYESL------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1207
Query: 64 KRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV 123
++ + + + + + E+E + + Y+++C + D L ++ K+
Sbjct: 1208 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE------- 1260
Query: 124 LNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKEC 183
E LQ+ L L + +Q L S + + D+ L + EL+
Sbjct: 1261 -TEVLQTDHKNLKSLLNNSKLEQT--RLEAEFSKLKEQYQQLDITSTKLNNQCELL---- 1313
Query: 184 SDLKIELQKAKQ--TDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQA 241
S LK L++ + D Q L++R L + ++ S ++ H E ++ + L+ + + +
Sbjct: 1314 SQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHV--EQRQYIDKLNELRRQKE 1371
Query: 242 ELLRKL 247
+L K+
Sbjct: 1372 KLEEKI 1377
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 58.2 bits (139), Expect = 1e-08
Identities = 60/227 (26%), Positives = 113/227 (49%), Gaps = 24/227 (10%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE---EKLIARFEEETSSVGRE--QVNKAYHAYREVC 100
E+++ L EKEN LL+K+I L+ EK+ A E+E S + RE ++ K +++ +
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLT 686
Query: 101 IDRDNLK---SKLDKMNKD---NSESLKVLNEQLQSKEVELLQLRTEVETQ----QVMRN 150
++L+ S+LD+ N + N ESLK + ++ ++E +L +E E ++++
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746
Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
+ EV D++ L++ LE K+ L+ ELQ D E+ ++L+
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-----DLEMENQTLQKNLE 801
Query: 211 KLSISSDNMQHAYWE---LKREMSNLHLVTQVQAELLRKLKTSTAIK 254
+L ISS ++ E L++E S L + + ++L+ IK
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/281 (24%), Positives = 119/281 (42%), Gaps = 58/281 (20%)
Query: 6 EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
E I IL E H TV+ + S + A R+KD EKEN +L +
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEA--------------RVKDIEKENKILHES 595
Query: 66 IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNS------E 119
I+ KL ++ E E + Q+ K Y+E + L+++L + K+N
Sbjct: 596 IKETSSKL-SKIEFE-----KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 120 SLKVLNEQLQSKEVELLQLRTE----VETQQVMRNLNPPSSNWE---------------- 159
+LK+ E++++ E E +L E +T +NL + E
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709
Query: 160 VEKLSC--------DLKIHGLEQELELMRKECSDLKIELQKAKQTD-PYQEDNLKSRDLQ 210
VE L C L+ LE E E ++K LK +K ++ + YQ +++++ LQ
Sbjct: 710 VESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ 769
Query: 211 KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTST 251
K + +N +L+ E+ +L + Q + L +LK S+
Sbjct: 770 K---TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/201 (25%), Positives = 97/201 (48%), Gaps = 21/201 (10%)
Query: 53 KDSEKENSLLKKRIRFLEE---KLIARFEEETSSVGREQVNKAYHAYREVC-IDRDNLKS 108
KD KE + L+K I L E + I E+E E +N+ + R+ I +
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQEN-----EHLNQTVSSLRQRSQISAEARVK 583
Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK 168
++K NK ES+K + +L E E Q++ E+E + E+L +L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK--------EKGERAEELENEL- 634
Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKR 228
H LE+E EL++K+ ++LKI +K + + QE++ R+ +KL + D+ ++ ++L+
Sbjct: 635 -HHLEKENELLQKKITNLKITCEKIEALE--QENSELERENRKLKKTLDSFKNLTFQLES 691
Query: 229 EMSNLHLVTQVQAELLRKLKT 249
+ + EL R +++
Sbjct: 692 LEKENSQLDEENLELRRNVES 712
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 23/187 (12%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS-VGREQVNKAYHAYREVCIDRD 104
E+ ++L D ++E ++ ++ L+++ + + S+ + R++++ A RE + D
Sbjct: 268 EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVD 323
Query: 105 NLKSKLDKMNK--DNSESLKVLNEQLQSKEVELLQLRTEVETQ-QVMRNLNPPSSNWEVE 161
L+S++ + + + E K E+L+ LL+ +T +E Q + R + E E
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQH 221
L K+H +E E ++ RK+ +L E+N+ QK S+ D H
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEEL-------------MEENMTLEMAQKQSM--DESLH 428
Query: 222 AYWELKR 228
WEL++
Sbjct: 429 LGWELEQ 435
Score = 40.8 bits (94), Expect = 0.002
Identities = 51/218 (23%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQ-----VNKAYHAYREV 99
Y++ RLK+ EKEN L KR + L+ E+ S + Q + K H ++
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Query: 100 CIDRDNL----KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVE-----TQQVMRN 150
++++ L +S D+ S+ L + L+ KE ++ L +E QQ+ +
Sbjct: 936 GLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995
Query: 151 LNPPSSNWEVEKLSCDLK--------IHGLEQELELMRKECS-------DLKIELQKAKQ 195
L N+E K D + I G + + E +E + D IE+++
Sbjct: 996 LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNA 1055
Query: 196 TDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNL 233
T ++ LK++ L++L ++N+Q L+R+ +L
Sbjct: 1056 TLQAEKQALKTQ-LKQLETQNNNLQAQILALQRQTVSL 1092
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/221 (21%), Positives = 98/221 (44%), Gaps = 39/221 (17%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE--EKLIARFEEETSSVGREQVNKAYHAYREVCIDR 103
+ ++ L+D E EN L+K + L+ K + + E+E S+ +E +++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ----------LEK 829
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKL 163
D K +L+K NK + ++ + L+ V++ L E +T S + K
Sbjct: 830 D--KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL---------SKEIGIYKE 878
Query: 164 SCDLKIHGLEQE-LELMRKECSDLK--------IELQKAKQTDPYQEDNLKSRDLQKLSI 214
SC +++ LE+E EL+++ D+K + +K K + + +L+K+ +
Sbjct: 879 SC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGL 937
Query: 215 SSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKK 255
+ + + H E S ++++L LK S IK+
Sbjct: 938 NKERLLH------DEQSTDDRYKLLESKLESTLKKSLEIKE 972
Score = 37.0 bits (84), Expect = 0.031
Identities = 51/246 (20%), Positives = 108/246 (43%), Gaps = 28/246 (11%)
Query: 8 DICILNHEKA---HKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE-KENSLLK 63
D I +HEK H+R S+ ++ H L +A+++++ +D E + N LLK
Sbjct: 1153 DSLIKDHEKLELLHERQASEYESL------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1206
Query: 64 KRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV 123
++ + + + + + E+E + + Y+++C + D L ++ K+
Sbjct: 1207 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE------- 1259
Query: 124 LNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKEC 183
E LQ+ L L + +Q L S + + D+ L + EL+
Sbjct: 1260 -TEVLQTDHKNLKSLLNNSKLEQT--RLEAEFSKLKEQYQQLDITSTKLNNQCELL---- 1312
Query: 184 SDLKIELQKAKQ--TDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQA 241
S LK L++ + D Q L++R L + ++ S ++ H E ++ + L+ + + +
Sbjct: 1313 SQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHV--EQRQYIDKLNELRRQKE 1370
Query: 242 ELLRKL 247
+L K+
Sbjct: 1371 KLEEKI 1376
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 57.4 bits (137), Expect = 2e-08
Identities = 63/261 (24%), Positives = 121/261 (46%), Gaps = 35/261 (13%)
Query: 13 NHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEK 72
+ +K ++ + T + + +S+ L EDIK L+ S L++ ++ +
Sbjct: 292 SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKT 351
Query: 73 LIARFEEETSSVGREQVNKAYHAY--------REVCIDRDNLKSKLDKMNKDNSESLKVL 124
+ EE+ + + E+ NKA A+ VC + L+++ ++ K N + LK+L
Sbjct: 352 ICQLTEEKETQM--EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK-NEDQLKIL 408
Query: 125 NEQLQSKEVELLQL-----RTEVETQQVMRNLNPPSS----NWEVEKLSCDLKIHGLEQE 175
+LQ K EL ++ EVE +++ + L + N + EK++ +LK G EQE
Sbjct: 409 TMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK--GTEQE 466
Query: 176 ----LELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMS 231
L+ KE DL+I+L ++ Y S++++ L +N + EL +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYY-----SKEVKDLKTELENEKLKNTELTSHCN 521
Query: 232 NLHL----VTQVQAELLRKLK 248
L L +TQ +++ +LK
Sbjct: 522 KLSLENKELTQETSDMTLELK 542
Score = 46.2 bits (108), Expect = 5e-05
Identities = 55/216 (25%), Positives = 89/216 (41%), Gaps = 42/216 (19%)
Query: 38 HFALVTAYEDI-------KKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVN 90
HF L YE I KK + D EK+ SLL +I E K+ ++ + + E +
Sbjct: 240 HFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKM-----KDLTFLLEESRD 294
Query: 91 KAYHAYREVCIDRDNLKSKLDKMNKDNSE-------------SLKVLNEQLQSKEVELLQ 137
K + + +NLK ++K + E + K L E LQ + Q
Sbjct: 295 KVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQ 354
Query: 138 LRTEVETQQVMRNLNPPSSNW---EVEKLSCDLK--IHGLEQELELMRKECSDLKIELQK 192
L E ETQ N + ++ E E C L+ + +Q LE + L +ELQK
Sbjct: 355 LTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQK 414
Query: 193 AKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKR 228
KS +L++++ ++N + ELK+
Sbjct: 415 ------------KSSELEEMTKLTNNKEVELEELKK 438
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/173 (23%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFE--EETSSVGREQVNKAYHAYREVCIDRD 104
D+ LK+ +++ + KK+ EE+++ + E +ET + R N+ + E+ RD
Sbjct: 536 DMTLELKNQQEDINNNKKQ----EERMLKQIENLQETETQLR---NELEYVREELKQKRD 588
Query: 105 NLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLS 164
+K KLDK + E+ L +Q+++K + +L QQ + L + +
Sbjct: 589 EVKCKLDK----SEENCNNLRKQVENKNKYIEEL------QQENKALKKKGTAESKQLNV 638
Query: 165 CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSD 217
++K++ LE ELE +++ ++ QK + E+NL +++K + +D
Sbjct: 639 YEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENL-LEEVEKAKVIAD 690
Score = 30.8 bits (68), Expect = 2.2
Identities = 44/194 (22%), Positives = 80/194 (41%), Gaps = 34/194 (17%)
Query: 33 ESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKA 92
ES F +T + +K ++D + L + + + K+IA +E + +E +
Sbjct: 651 ESAKQKFGEIT--DTYQKEIEDKKISEENLLEEVE--KAKVIA---DEAVKLQKEIDKRC 703
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
H E+ + K + DK+ ++ L + +SKE E LR +E +
Sbjct: 704 QHKIAEMVALMEKHKHQYDKIIEERDSELGLY----KSKEQEQSSLRASLEIEL------ 753
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
SN + E LS ++++LE+ R+E LK E ++ T LK + +K
Sbjct: 754 ---SNLKAELLS-------VKKQLEIEREEKEKLKREAKENTAT-------LKEKKDKKT 796
Query: 213 SISSDNMQHAYWEL 226
YW+L
Sbjct: 797 QTFLLETPEIYWKL 810
>gi|19743569 TRAF interacting protein TANK isoform a [Homo sapiens]
Length = 425
Score = 56.6 bits (135), Expect = 4e-08
Identities = 41/184 (22%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 87 EQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEV---- 142
EQ+NKAY A+R+ C+DRD+ +L + ++ + ++ EQL ++ + +L++++
Sbjct: 7 EQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVN 66
Query: 143 ETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQED 202
TQ P + E K + L + + +++ + ++++ + + P +E
Sbjct: 67 STQDNNYGCVPLLEDSETRKNNLTLD----QPQDKVISGIAREKLPKVRRQEVSSPRKET 122
Query: 203 NLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLK-TSTAIKKACA-PV 260
+ +S L N++ +W+LK E + ++ + Q + L KL TA + C+ P+
Sbjct: 123 SARSLG-SPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVPI 181
Query: 261 GCSE 264
C++
Sbjct: 182 QCTD 185
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 53.1 bits (126), Expect = 4e-07
Identities = 54/214 (25%), Positives = 94/214 (43%), Gaps = 19/214 (8%)
Query: 53 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
K E LLK + F E +RF +E + + N+ H L+ KL
Sbjct: 288 KSKEDRQKLLKLEVDF--EHKASRFSQEHEEMNAKLANQESH--------NRQLRLKLVG 337
Query: 113 MNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCD-LKIHG 171
+ + E L+ N+ LQ E EL +LR ++ + + S EVE L L++ G
Sbjct: 338 LTQ-RIEELEETNKNLQKAEEELQELRDKIAKGECGNS----SLMAEVENLRKRVLEMEG 392
Query: 172 LEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMS 231
++E+ +C +L+ +LQ+ + +E L+ LQK + ++ A+ + K E +
Sbjct: 393 KDEEITKTESQCRELRKKLQEEEHHS--KELRLEVEKLQKRMSELEKLEEAFSKSKSECT 450
Query: 232 NLHLVTQVQAELLRKLKTS-TAIKKACAPVGCSE 264
LHL + + L + L +K + CSE
Sbjct: 451 QLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 50.4 bits (119), Expect = 3e-06
Identities = 52/221 (23%), Positives = 102/221 (46%), Gaps = 14/221 (6%)
Query: 38 HFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
H + A+E KK + KE +R+ EK +F+E+ ++ Q + +
Sbjct: 745 HEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHH 804
Query: 98 EVCIDR--DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVE--TQQVMRNLNP 153
+DR K ++ K N E+LK L Q+ + +++ QL + +E ++++ +LN
Sbjct: 805 LESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQ 864
Query: 154 PSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRD--LQK 211
N EK LK +E+ ++KE LQ+ + + + L+ + LQ+
Sbjct: 865 LEGN--KEKFEKQLK--KKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQ 920
Query: 212 LSISSDNMQHAYWELKREMSNLHLVTQVQ----AELLRKLK 248
+I + ++ +L++++S L Q Q AE LRK++
Sbjct: 921 ETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKME 961
Score = 37.4 bits (85), Expect = 0.024
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 19/192 (9%)
Query: 54 DSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCI----DRDNLKSK 109
+ +KEN + ++ L+ ++ EET V Q++ A +E + + K K
Sbjct: 818 EMKKENMKKDEALKALQNQV----SEETIKV--RQLDSALEICKEELVLHLNQLEGNKEK 871
Query: 110 LDKMNKDNSES-------LKVLNEQLQ-SKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
+K K SE LK+ N LQ + E ++ T + QQ+++ + E
Sbjct: 872 FEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDT 931
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQH 221
+ + ++ LEQEL+ R E S K+ + K E +LK + + +L+ ++ ++
Sbjct: 932 QTKLEKQVSKLEQELQKQR-ESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKI 990
Query: 222 AYWELKREMSNL 233
+ K E+S +
Sbjct: 991 EMDQYKEELSKM 1002
Score = 34.3 bits (77), Expect = 0.20
Identities = 52/228 (22%), Positives = 88/228 (38%), Gaps = 37/228 (16%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
LVT E+++ +L E ENS LK V + +E
Sbjct: 639 LVTGIEELRTKLIQIEAENSDLK--------------------VNMAHRTSQFQLIQEEL 678
Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE--------VETQQVMRNLN 152
+++ + SKL+ L L +QL+ K V + + +E + +R+L
Sbjct: 679 LEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLE 738
Query: 153 PPSSNWEVEKLSCDL----KIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLK--S 206
+ N E EK+ KIH LEQ E M K+ L+ +L+K Q QE +
Sbjct: 739 -TNINTEHEKICLAFEKAKKIH-LEQHKE-MEKQIERLEAQLEKKDQQFKEQEKTMSMLQ 795
Query: 207 RDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK 254
+D+ +++ E K EM ++ + L+ + IK
Sbjct: 796 QDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIK 843
Score = 34.3 bits (77), Expect = 0.20
Identities = 47/209 (22%), Positives = 91/209 (43%), Gaps = 45/209 (21%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
+ + K ++ +K+ +++R +EEK + E + + R++V + R+V I+ D
Sbjct: 937 KQVSKLEQELQKQRESSAEKLRKMEEKCESAAHE--ADLKRQKVIELTGTARQVKIEMDQ 994
Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
K +L KM K+ + L ++K + L QL
Sbjct: 995 YKEELSKMEKE----IMHLKRDGENKAMHLSQL--------------------------- 1023
Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWE 225
D+ + + ELE +L+ +LQ + +T+ + LQK + +Q+A+ E
Sbjct: 1024 DMILDQTKTELEKKTNAVKELE-KLQHSTETE-------LTEALQKREVLETELQNAHGE 1075
Query: 226 LK---REMSNLHLVTQVQAELLRKLKTST 251
LK R++ L V Q +A+L + K +T
Sbjct: 1076 LKSTLRQLQELRDVLQ-KAQLSLEEKYTT 1103
Score = 31.2 bits (69), Expect = 1.7
Identities = 41/189 (21%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 75 ARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES------LKVLNEQL 128
A ++E S+ RE++NK + +L +K + ++ + ++S L+ +Q
Sbjct: 225 APVDQEIKSL-REKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQA 283
Query: 129 QSK---EVELLQLRTEVETQ-QVMR---NLNPPSSNWEVEKLSCDLKIHGLEQELELMRK 181
S E +++ L EV Q +V+R N S +EK EQ L+ ++
Sbjct: 284 ASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEK----------EQSLQESKE 333
Query: 182 ECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQA 241
EC LK++L +QT ++ R + +++ + A+ + K++++ Q +
Sbjct: 334 ECIKLKVDL--LEQT---KQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEE 388
Query: 242 ELLRKLKTS 250
E+L + T+
Sbjct: 389 EILERNLTN 397
Score = 30.8 bits (68), Expect = 2.2
Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRI---RFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
L + ED+K+ K+ + + L + + + E L AR + E + E V AY
Sbjct: 1286 LSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE-VESLKEAYH 1344
Query: 98 EVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVET--QQV 147
I +K S++ LNEQL+ ++EL + + V QQV
Sbjct: 1345 MEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQV 1396
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/216 (26%), Positives = 99/216 (45%), Gaps = 46/216 (21%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE-------------EKLIARFEEETSSVGREQVNKA 92
E+++++L+D EK+ S LK+R++ L+ E+ +A +E T +EQ ++
Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE-KERTIERLKEQRDRD 639
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
+E + DN K L KD E + +L L KE LL L+
Sbjct: 640 EREKQE---EIDNYKKDL----KDLKEKVSLLQGDLSEKEASLLDLKEH----------- 681
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
+S+ L D ++ LE LE ++EC ++ +L+KA E L++R ++
Sbjct: 682 --ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA------HEAALEARASPEM 733
Query: 213 SISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLK 248
SD +QH E+ R ++ QAE+ R L+
Sbjct: 734 ---SDRIQHLEREITRYKDE---SSKAQAEVDRLLE 763
Score = 37.4 bits (85), Expect = 0.024
Identities = 47/222 (21%), Positives = 103/222 (46%), Gaps = 25/222 (11%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
D++ +LK+ +EN LL+K + E KL +SS+ + + +E + +D
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKL-------SSSMNSIKTFWSPELKKERALRKDE- 204
Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL-NPPSSNWEVEKLSC 165
SK+ E +V+ E+ Q ++ + L+ E+ Q+ + L SS+ E
Sbjct: 205 ASKITIW----KEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVA 260
Query: 166 DL------KIHGLEQ----ELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RDLQKLS 213
+L ++H + EL L+RK ++++ ++ KQT +++++K LQ
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 320
Query: 214 ISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKK 255
+S+ + + +R V +++ L +K K ++ +++
Sbjct: 321 LSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLRE 362
Score = 36.6 bits (83), Expect = 0.040
Identities = 48/217 (22%), Positives = 91/217 (41%), Gaps = 38/217 (17%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
E +K+ L E + LKK+ L+ + I + ++E S E +
Sbjct: 441 EQLKEELSSKEAQWEELKKKAAGLQAE-IGQVKQELSRKDTELLA--------------- 484
Query: 106 LKSKLDKMNK---DNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEK 162
L++KL+ + D+ + ++VL E L +KE L+TEV+ ++ N + +
Sbjct: 485 LQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK- 543
Query: 163 LSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHA 222
+I + +E E DLK L ++K R + L +N+Q
Sbjct: 544 -----QIQDMAEEKGTQAGEIHDLKDML------------DVKERKVNVLQKKIENLQEQ 586
Query: 223 YWELKREMSNL-HLVTQVQAELLRKLKTSTAIKKACA 258
+ +++MS+L V +QA+ T +++A A
Sbjct: 587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALA 623
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/216 (26%), Positives = 99/216 (45%), Gaps = 46/216 (21%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE-------------EKLIARFEEETSSVGREQVNKA 92
E+++++L+D EK+ S LK+R++ L+ E+ +A +E T +EQ ++
Sbjct: 553 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE-KERTIERLKEQRDRD 611
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
+E + DN K L KD E + +L L KE LL L+
Sbjct: 612 EREKQE---EIDNYKKDL----KDLKEKVSLLQGDLSEKEASLLDLKEH----------- 653
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
+S+ L D ++ LE LE ++EC ++ +L+KA E L++R ++
Sbjct: 654 --ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA------HEAALEARASPEM 705
Query: 213 SISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLK 248
SD +QH E+ R ++ QAE+ R L+
Sbjct: 706 ---SDRIQHLEREITRYKDE---SSKAQAEVDRLLE 735
Score = 37.4 bits (85), Expect = 0.024
Identities = 47/222 (21%), Positives = 103/222 (46%), Gaps = 25/222 (11%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
D++ +LK+ +EN LL+K + E KL +SS+ + + +E + +D
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKL-------SSSMNSIKTFWSPELKKERALRKDE- 204
Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL-NPPSSNWEVEKLSC 165
SK+ E +V+ E+ Q ++ + L+ E+ Q+ + L SS+ E
Sbjct: 205 ASKITIW----KEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVA 260
Query: 166 DL------KIHGLEQ----ELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RDLQKLS 213
+L ++H + EL L+RK ++++ ++ KQT +++++K LQ
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 320
Query: 214 ISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKK 255
+S+ + + +R V +++ L +K K ++ +++
Sbjct: 321 LSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLRE 362
Score = 35.8 bits (81), Expect = 0.068
Identities = 54/260 (20%), Positives = 105/260 (40%), Gaps = 42/260 (16%)
Query: 15 EKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLI 74
E+ H+R P S A AL T E ++ E+ L++ I+ L+
Sbjct: 362 EEMHRRFENAPDS--------AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGA 413
Query: 75 ARFEEETSSVGREQVNKAYHAYREVCIDRDN------------LKSKLDKMNK---DNSE 119
EE + + +V +++ + + I + L++KL+ + D+ +
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQ 473
Query: 120 SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELM 179
++VL E L +KE L+TEV+ ++ N + + +I + +E
Sbjct: 474 HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK------QIQDMAEEKGTQ 527
Query: 180 RKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNL-HLVTQ 238
E DLK L ++K R + L +N+Q + +++MS+L V
Sbjct: 528 AGEIHDLKDML------------DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKS 575
Query: 239 VQAELLRKLKTSTAIKKACA 258
+QA+ T +++A A
Sbjct: 576 LQADTTNTDTALTTLEEALA 595
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/303 (25%), Positives = 140/303 (46%), Gaps = 56/303 (18%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 502 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 556
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 557 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 616
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 617 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 676
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RD 208
+ E EKL ++ E L M+ + S + EL + KQ Q++N S
Sbjct: 677 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 736
Query: 209 LQKLSISSDNMQHAYWELKREMSNL--HLVT-QVQAELLRK--LKTSTAIKKACAPVGCS 263
LQ ++ ++ A E++ ++SNL HL + +V+ L K L+ A+ A P
Sbjct: 737 LQVIT----TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSY 792
Query: 264 EDL 266
E L
Sbjct: 793 EKL 795
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/303 (25%), Positives = 140/303 (46%), Gaps = 56/303 (18%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 491 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 545
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 546 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 605
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 606 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 665
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RD 208
+ E EKL ++ E L M+ + S + EL + KQ Q++N S
Sbjct: 666 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 725
Query: 209 LQKLSISSDNMQHAYWELKREMSNL--HLVT-QVQAELLRK--LKTSTAIKKACAPVGCS 263
LQ ++ ++ A E++ ++SNL HL + +V+ L K L+ A+ A P
Sbjct: 726 LQVIT----TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSY 781
Query: 264 EDL 266
E L
Sbjct: 782 EKL 784
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/303 (25%), Positives = 140/303 (46%), Gaps = 56/303 (18%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 470 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 524
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 525 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 584
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 585 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 644
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RD 208
+ E EKL ++ E L M+ + S + EL + KQ Q++N S
Sbjct: 645 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 704
Query: 209 LQKLSISSDNMQHAYWELKREMSNL--HLVT-QVQAELLRK--LKTSTAIKKACAPVGCS 263
LQ ++ ++ A E++ ++SNL HL + +V+ L K L+ A+ A P
Sbjct: 705 LQVIT----TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSY 760
Query: 264 EDL 266
E L
Sbjct: 761 EKL 763
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/303 (25%), Positives = 140/303 (46%), Gaps = 56/303 (18%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RD 208
+ E EKL ++ E L M+ + S + EL + KQ Q++N S
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 733
Query: 209 LQKLSISSDNMQHAYWELKREMSNL--HLVT-QVQAELLRK--LKTSTAIKKACAPVGCS 263
LQ ++ ++ A E++ ++SNL HL + +V+ L K L+ A+ A P
Sbjct: 734 LQVIT----TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSY 789
Query: 264 EDL 266
E L
Sbjct: 790 EKL 792
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/303 (25%), Positives = 140/303 (46%), Gaps = 56/303 (18%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RD 208
+ E EKL ++ E L M+ + S + EL + KQ Q++N S
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 733
Query: 209 LQKLSISSDNMQHAYWELKREMSNL--HLVT-QVQAELLRK--LKTSTAIKKACAPVGCS 263
LQ ++ ++ A E++ ++SNL HL + +V+ L K L+ A+ A P
Sbjct: 734 LQVIT----TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSY 789
Query: 264 EDL 266
E L
Sbjct: 790 EKL 792
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/303 (25%), Positives = 140/303 (46%), Gaps = 56/303 (18%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RD 208
+ E EKL ++ E L M+ + S + EL + KQ Q++N S
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 733
Query: 209 LQKLSISSDNMQHAYWELKREMSNL--HLVT-QVQAELLRK--LKTSTAIKKACAPVGCS 263
LQ ++ ++ A E++ ++SNL HL + +V+ L K L+ A+ A P
Sbjct: 734 LQVIT----TLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSY 789
Query: 264 EDL 266
E L
Sbjct: 790 EKL 792
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/233 (24%), Positives = 108/233 (46%), Gaps = 27/233 (11%)
Query: 31 GDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVN 90
G ++ + L ++D++K L++ E +L+++I+ L+ L+ ++E V E++
Sbjct: 1821 GKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVR--QKEVHRVEMEELT 1878
Query: 91 KAYHAYREVC-IDRDN-----LKSKLDKMNKDNSESLKVL-NEQLQSKEVELLQLRTEVE 143
Y + + +D N L+ ++ +K + K+L N + Q ++E E E
Sbjct: 1879 SKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAERE 1938
Query: 144 TQQVMRNLNPPSSNWEVEKLSCDLKIHGLE--QELELMRKECSDLKIELQKAKQTDPYQE 201
Q++ + E+ +L DL++ E QELE+++KE + E K +Q D
Sbjct: 1939 KQKLGK---------EIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDL--- 1986
Query: 202 DNLKSRDLQKLSISSDNMQHAYWELKREMS---NLHLVTQVQAELLRKLKTST 251
LK K + N Q A E + EM+ ++ +V+AELL + T
Sbjct: 1987 -ELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 2038
Score = 42.4 bits (98), Expect = 7e-04
Identities = 32/149 (21%), Positives = 77/149 (51%), Gaps = 14/149 (9%)
Query: 48 IKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLK 107
++ ++ EK+NS ++++++ L + ++ E+ NK +++ ++++N+
Sbjct: 863 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG---------NKEQEQTKQILVEKENM- 912
Query: 108 SKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDL 167
+ +M + + +++L ++L +KE + L E ET+ + + +++ L
Sbjct: 913 --ILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETL 970
Query: 168 KIHGLEQELELMRKECSDLKIEL-QKAKQ 195
K L+QE +L +KE + +EL QK KQ
Sbjct: 971 KKKLLDQEAKL-KKELENTALELSQKEKQ 998
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/230 (24%), Positives = 100/230 (43%), Gaps = 31/230 (13%)
Query: 46 EDIKKRLKDSE-KENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC---- 100
E IK+ +D E K NS LK+ +R +L A+ E+E +E +NKA E+
Sbjct: 1977 EKIKQEQEDLELKHNSTLKQLMREFNTQL-AQKEQELEMTIKETINKAQEVEAELLESHQ 2035
Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELL----QLRTEVE------TQQVMRN 150
+ + L K+ + + D + K E L ++E E+ L+T++E Q++ +
Sbjct: 2036 EETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQE 2095
Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
NP + N + +L L Q+ L+ SD K++ Q+ ++ ED LK +
Sbjct: 2096 ENPGNDNVTIMELQTQ-----LAQKTTLI----SDSKLKEQEFREQIHNLEDRLKKYEKN 2146
Query: 211 KLSIS------SDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK 254
+ + N+ H L E + + +V E + +T T K
Sbjct: 2147 VYATTVGTPYKGGNLYHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAK 2196
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/160 (24%), Positives = 74/160 (46%), Gaps = 9/160 (5%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDRD 104
E IK K SE+E L++ + ++++++ ++ + EQ+ K + +E+
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSE----EQIAKLQKLHEKELARKEQ 494
Query: 105 NLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLS 164
L KL ++ E +KV E+ QS E L++ E E Q+ + L +
Sbjct: 495 ELTKKLQTREREFQEQMKVALEKSQS---EYLKISQEKEQQESLA-LEELELQKKAILTE 550
Query: 165 CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNL 204
+ K+ L+QE E R +L+ L+K+ Q + Q +L
Sbjct: 551 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590
Score = 36.6 bits (83), Expect = 0.040
Identities = 52/247 (21%), Positives = 107/247 (43%), Gaps = 18/247 (7%)
Query: 6 EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
E+ I +L K + V +E+V+SHF + Y++ +L+ +E + +
Sbjct: 1735 EEKISVLQRNLTEKEKLLQRVG-QEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM 1793
Query: 66 IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLN 125
I L+E+L EE+ + + A H +E + K L+ + D ++L+
Sbjct: 1794 IGHLQEEL----EEKNK---KYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKE 1846
Query: 126 EQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSD 185
Q E ++ +L + + Q+ + + + EKL ++ G + EL+ +
Sbjct: 1847 LTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTE- 1905
Query: 186 LKIELQKAKQTDPYQEDNLKSR--DLQ-KLSISSDNMQHAYWELKREMSNLHLVT---QV 239
E K+ P N++++ DL+ KL+ + Q E+ R +L ++ Q
Sbjct: 1906 ---EKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ 1962
Query: 240 QAELLRK 246
+ E+L+K
Sbjct: 1963 ELEILKK 1969
Score = 35.8 bits (81), Expect = 0.068
Identities = 46/228 (20%), Positives = 100/228 (43%), Gaps = 35/228 (15%)
Query: 49 KKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS----VGREQVNKAYHAYREVCIDRD 104
+ +L+D ++E + RI LE L +E + + K H +E+ + +
Sbjct: 552 ENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN-KEITVMVE 610
Query: 105 NLKSKLDKMNKDN----SESLKVLNEQLQSKEVELLQLRTEVETQQVMRN---------- 150
K++L+ + +E L+VL +Q Q+ E+E L+ + E E + ++++
Sbjct: 611 KHKTELESLKHQQDALWTEKLQVLKQQYQT-EMEKLREKCEQEKETLLKDKEIIFQAHIE 669
Query: 151 -LNPPS------SNWEVEKLSCDLKI-----HGLEQELELMRKECSDLKIELQKAKQTDP 198
+N + E+E LS +L H LE+EL +++ + +K EL+
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQK 729
Query: 199 YQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRK 246
+++ +S + A LK +++ L L+ + + + L++
Sbjct: 730 NHHQQQVDSIIKEHEVSIQRTEKA---LKDQINQLELLLKERDKHLKE 774
Score = 35.4 bits (80), Expect = 0.089
Identities = 40/202 (19%), Positives = 84/202 (41%), Gaps = 27/202 (13%)
Query: 56 EKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNK 115
EKEN + K ++ E L+ E G +Q + ++++ ++L K
Sbjct: 1301 EKENQI--KSMKADIESLVTEKEALQKEGGNQQ---------QAASEKESCITQLKKELS 1349
Query: 116 DNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQE 175
+N ++ ++ E+L+ K+VE+ L ++ V +L + + E
Sbjct: 1350 ENINAVTLMKEELKEKKVEISSLSKQLTDLNV--------------QLQNSISLSEKEAA 1395
Query: 176 LELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSD-NMQHAYWELKREMS-NL 233
+ +RK+ + K EL Q ++ D L + L D + + + W+ K +
Sbjct: 1396 ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQ 1455
Query: 234 HLVTQVQAELLRKLKTSTAIKK 255
H T + ++ +LK+ A +K
Sbjct: 1456 HQNTVKELQIQLELKSKEAYEK 1477
Score = 34.3 bits (77), Expect = 0.20
Identities = 33/208 (15%), Positives = 91/208 (43%), Gaps = 26/208 (12%)
Query: 49 KKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKS 108
K + + ++ +N++ + +I+ + A ++E ++ +E++++ + + + ++ KS
Sbjct: 1448 KAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1507
Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVET-QQVMRNLNPPSS----------- 156
K++K + LK ++ E + Q E+E+ +V++N N
Sbjct: 1508 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQ 1567
Query: 157 --------------NWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQED 202
E + L+ + +++ ++ ELE +KE + + ++ ++ ED
Sbjct: 1568 HFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALED 1627
Query: 203 NLKSRDLQKLSISSDNMQHAYWELKREM 230
L+S KL+ + +K+++
Sbjct: 1628 RLESESAAKLAELKRKAEQKIAAIKKQL 1655
Score = 33.5 bits (75), Expect = 0.34
Identities = 50/229 (21%), Positives = 100/229 (43%), Gaps = 39/229 (17%)
Query: 46 EDIKKRLKDSEK------ENSLLK--KRIRFLEEKLIARFEEETSSVG----------RE 87
E +KK+L D E EN+ L+ ++ + K++ + ++ + +E
Sbjct: 968 ETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE 1027
Query: 88 QVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQV 147
Q+ +R D ++ K K+N+ E ++ QLQ KE E+ +L+ ++
Sbjct: 1028 QIESLTEVHRRELNDVISIWEK--KLNQQAEELQEIHEIQLQEKEQEVAELKQKI----- 1080
Query: 148 MRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIEL-QKAKQTDPYQEDNLKS 206
L E+ K LK G++Q+ L ++L+ +L QK+ + +D K
Sbjct: 1081 ---LLFGCEKEEMNKEITWLKEEGVKQDTTL-----NELQEQLKQKSAHVNSLAQDETKL 1132
Query: 207 R-DLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ----AELLRKLKTS 250
+ L+KL + + L+ ++ L ++ + +EL KLKT+
Sbjct: 1133 KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTT 1181
Score = 33.1 bits (74), Expect = 0.44
Identities = 48/213 (22%), Positives = 92/213 (43%), Gaps = 34/213 (15%)
Query: 44 AYED----IKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREV 99
AYE+ ++++L D E E LL K++ +E + ++ V A++
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQ-------------KKDVCTELDAHK-- 860
Query: 100 CIDRDNLKSKLDKMNKDNSESLKVLNEQLQSK-------EVELLQLRTEVETQQV-MRNL 151
I +L +L+K N + + +K L + +SK + + Q+ E E + MR
Sbjct: 861 -IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREG 919
Query: 152 NPPSSNWEVEKLSC-DLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
+KLS + IH L +E E K + + +++K KQ ++ LK + L
Sbjct: 920 QKKEIEILTQKLSAKEDSIHILNEEYETKFK---NQEKKMEKVKQKAKEMQETLKKKLLD 976
Query: 211 KLSISSDNMQHAYWEL--KREMSNLHLVTQVQA 241
+ + +++ EL K + N ++ QA
Sbjct: 977 QEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1009
Score = 32.3 bits (72), Expect = 0.76
Identities = 31/163 (19%), Positives = 70/163 (42%), Gaps = 7/163 (4%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAY---HAYREVCI 101
++++ ++L+ ++ R++ EEK++ E + S+ E K H V
Sbjct: 1559 HKELVQKLQHFQELGEEKDNRVKEAEEKILT-LENQVYSMKAELETKKKELEHVNLSVKS 1617
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVEL---LQLRTEVETQQVMRNLNPPSSNW 158
+ LK+ D++ +++ L L + + K + L + E + +Q + S
Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1677
Query: 159 EVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQE 201
+ + ++H LE++L+ + S+ I + AK Y E
Sbjct: 1678 NTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTE 1720
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 47.8 bits (112), Expect = 2e-05
Identities = 52/227 (22%), Positives = 98/227 (43%), Gaps = 39/227 (17%)
Query: 33 ESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKA 92
+ + H A + ED+K+ K+ E L+ +++ LE++ + R E+E S +E +N+
Sbjct: 472 DQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERL-RTEDELSKY-KEIINR- 528
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
+ +++ LDK+ ++ L EQLQ + E+ L+ EVE
Sbjct: 529 ---------QKAEIQNLLDKV-----KTADQLQEQLQRGKQEIENLKEEVE--------- 565
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI--ELQKAKQTDPYQEDNLKSRDLQ 210
S + I+ L++++E RK S+L + E +K E N
Sbjct: 566 -----------SLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFD 614
Query: 211 KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKAC 257
K+S S +Q ++K+ NL + EL ++ + + AC
Sbjct: 615 KVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELAC 661
Score = 37.0 bits (84), Expect = 0.031
Identities = 54/245 (22%), Positives = 107/245 (43%), Gaps = 20/245 (8%)
Query: 33 ESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGR--EQVN 90
E + SH V ++ K DS KE K +++ KL + +EE + + + +
Sbjct: 383 EDINSHVIKVKWAQNKLKAEMDSHKET---KDKLKETTTKL-TQAKEEADQIRKNCQDMI 438
Query: 91 KAYHAYREVCIDRDNLK-----SKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQ 145
K Y E+ + + K +L+K ++ S+ L++ + ++ KE+E L+ RT E
Sbjct: 439 KTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKI--KELEDLK-RTFKEGM 495
Query: 146 QVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDL--KI----ELQKAKQTDPY 199
+R L E E+L + ++ ++ + + E +L K+ +LQ+ Q
Sbjct: 496 DELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQ 555
Query: 200 QEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKACAP 259
+ +NLK S+ +D + KRE L ++ ++ + S +++
Sbjct: 556 EIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDK 615
Query: 260 VGCSE 264
V CSE
Sbjct: 616 VSCSE 620
Score = 34.7 bits (78), Expect = 0.15
Identities = 31/160 (19%), Positives = 74/160 (46%), Gaps = 12/160 (7%)
Query: 91 KAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRN 150
K + ++C ++DNL+ +L K + + + + +QL+S+ EL + Q + ++
Sbjct: 218 KHQELFVDICSEKDNLREELKKRTETEKQHMNTI-KQLESRIEELNKEVKASRDQLIAQD 276
Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
+ ++ ++ K + Q +E K+C + + E K Y +S DL+
Sbjct: 277 VTAKNAVQQLHK--------EMAQRMEQANKKCEEARQE--KEAMVMKYVRGEKESLDLR 326
Query: 211 KLSISSD-NMQHAYWELKREMSNLHLVTQVQAELLRKLKT 249
K + + ++ A EL++ + + ++Q + L + +T
Sbjct: 327 KEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYET 366
Score = 28.9 bits (63), Expect = 8.4
Identities = 25/112 (22%), Positives = 48/112 (42%), Gaps = 11/112 (9%)
Query: 40 ALVTAYEDIKKRLKDSEKENS--------LLKKRIRFLEEKLIARFEEETSSVGREQVNK 91
+L + D++K ++ S K S L K + E + + + S Q+
Sbjct: 566 SLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQS 625
Query: 92 AYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVE 143
++ I NL+S+L K + E ++ L +L ++ E+ L T+VE
Sbjct: 626 QCEQMKQTNI---NLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVE 674
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 47.4 bits (111), Expect = 2e-05
Identities = 60/224 (26%), Positives = 104/224 (46%), Gaps = 23/224 (10%)
Query: 47 DIKKRLKDSEKENSLLKKRIRF---LEEKLIARFEEETSSVGREQVNKAYH-AYREVCID 102
D KR +D EK +L+++ ++ L++ LIA+ E+E RE+ A A +E
Sbjct: 715 DSAKRSEDREK-GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSS 773
Query: 103 RDNLKSKLDKMNKDNSESLKVLNEQLQ--SKEVELLQLRTEVETQ-QVMRNLNPPSSNWE 159
D ++DK+ + L+ L E ++ +K VE+L R+ Q Q + E
Sbjct: 774 HDQ---EMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEE 830
Query: 160 VEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLK--------SRDLQK 211
EKL + LE+ + ++++ DLK + KAK+T E ++ +R +K
Sbjct: 831 NEKLQG--RSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEK 888
Query: 212 LSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKK 255
++S+ EL+ NL TQ Q +L KLK + K+
Sbjct: 889 EAVSARRALEN--ELEAAQGNLSQTTQEQKQLSEKLKEESEQKE 930
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 47.0 bits (110), Expect = 3e-05
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 9/171 (5%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYRE----VCI 101
E+ KK+++D N L+K L+EK R + + + E + + A + +
Sbjct: 656 EEAKKQIEDL---NMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
D +N KL D +K L+ +L+ + E Q + +++T V+ N + E+
Sbjct: 713 DLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIG 772
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
L ++H +++ E + KE ++K Q+ ++ Y N RDL L
Sbjct: 773 DLK--RRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAAL 821
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/160 (20%), Positives = 68/160 (42%), Gaps = 9/160 (5%)
Query: 53 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
K+S L++R R + K + + + + + +++ A D KSK D
Sbjct: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATE---CDVRMSKSKSDN 173
Query: 113 MNKDNSE---SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKI 169
D + +K L ++K+VE+L LR E+ + +N S + + +
Sbjct: 174 QISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMA 233
Query: 170 H---GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
H +E L ++++ + ++ EL + K + +D L +
Sbjct: 234 HQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 47.0 bits (110), Expect = 3e-05
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 9/171 (5%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYRE----VCI 101
E+ KK+++D N L+K L+EK R + + + E + + A + +
Sbjct: 656 EEAKKQIEDL---NMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
D +N KL D +K L+ +L+ + E Q + +++T V+ N + E+
Sbjct: 713 DLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIG 772
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
L ++H +++ E + KE ++K Q+ ++ Y N RDL L
Sbjct: 773 DLK--RRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAAL 821
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/160 (20%), Positives = 68/160 (42%), Gaps = 9/160 (5%)
Query: 53 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
K+S L++R R + K + + + + + +++ A D KSK D
Sbjct: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATE---CDVRMSKSKSDN 173
Query: 113 MNKDNSE---SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKI 169
D + +K L ++K+VE+L LR E+ + +N S + + +
Sbjct: 174 QISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMA 233
Query: 170 H---GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
H +E L ++++ + ++ EL + K + +D L +
Sbjct: 234 HQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/168 (24%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDR 103
Y ++ ++D KE +L K+ + L+ +L ++E + +AY A R+ +
Sbjct: 538 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 597
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE-VETQQVMRNLNPPSSNWEVEK 162
D+L L+K+N SE+ K L + L + + QL E + ++ M+ LN
Sbjct: 598 DDLTQALEKLNHVTSET-KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFH 656
Query: 163 LSCDLKIHGLEQELELM--------RKECSDLKIELQKAKQTDPYQED 202
+L++H +++LE M ++ +DLK+ K +Q +QE+
Sbjct: 657 QESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEE 704
Score = 38.9 bits (89), Expect = 0.008
Identities = 57/216 (26%), Positives = 100/216 (46%), Gaps = 33/216 (15%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVG--REQVNKAYHAYREVCIDRD 104
D+ R+K +E +K + LEE L +E T + REQ+ K+ + + + +
Sbjct: 441 DMLDRIKHQHREQGSIKCK---LEEDL----QEATKLLEDKREQLKKSKEHEKLMEGELE 493
Query: 105 NLKS---KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
L+ K DK K+NS L+ NE L++ EL T++E+ +LN +++ +V
Sbjct: 494 ALRQEFKKKDKTLKENSRKLEEENENLRA---ELQCCSTQLES-----SLNKYNTSQQV- 544
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDP-YQEDNLKSRDLQKLSISSDNMQ 220
I L +E+ L ++ L+ +L KA Q + Y + + LS S Q
Sbjct: 545 -------IQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 597
Query: 221 HAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKA 256
+L + + L+ VT + + L++ T T KKA
Sbjct: 598 D---DLTQALEKLNHVTS-ETKSLQQSLTQTQEKKA 629
Score = 34.3 bits (77), Expect = 0.20
Identities = 61/268 (22%), Positives = 108/268 (40%), Gaps = 50/268 (18%)
Query: 42 VTAYEDIKKRLKD-----SEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY 96
V Y+++ K L+ SE++ +++K ++ LE L EE ++ + R+ +
Sbjct: 177 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMK-LELDLHGLREETSAHIERKDKDITILQC 235
Query: 97 R--EVCID---RDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVM--- 148
R E+ ++ L K DK ++ E L+ L ++L + LL+ E+E QQ M
Sbjct: 236 RLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATE 295
Query: 149 -------------RNLNPPSSNWEVEKLSCDL------------KIHGLEQELELMRKEC 183
+ + EV+KL L + ++E L
Sbjct: 296 LEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHL 355
Query: 184 SDLKIELQKAKQTDPYQEDNLK--SRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQA 241
D + +LQK D + D ++ R+LQ L S + K + SN V ++
Sbjct: 356 EDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAE------KEQTSNRKRVEELSL 409
Query: 242 EL---LRKLKTSTAIKKACAPVGCSEDL 266
EL LRKL+ S K+ +D+
Sbjct: 410 ELSEALRKLENSDKEKRQLQKTVAEQDM 437
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/168 (24%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDR 103
Y ++ ++D KE +L K+ + L+ +L ++E + +AY A R+ +
Sbjct: 683 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 742
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE-VETQQVMRNLNPPSSNWEVEK 162
D+L L+K+N SE+ K L + L + + QL E + ++ M+ LN
Sbjct: 743 DDLTQALEKLNHVTSET-KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFH 801
Query: 163 LSCDLKIHGLEQELELM--------RKECSDLKIELQKAKQTDPYQED 202
+L++H +++LE M ++ +DLK+ K +Q +QE+
Sbjct: 802 QESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEE 849
Score = 38.9 bits (89), Expect = 0.008
Identities = 57/216 (26%), Positives = 100/216 (46%), Gaps = 33/216 (15%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVG--REQVNKAYHAYREVCIDRD 104
D+ R+K +E +K + LEE L +E T + REQ+ K+ + + + +
Sbjct: 586 DMLDRIKHQHREQGSIKCK---LEEDL----QEATKLLEDKREQLKKSKEHEKLMEGELE 638
Query: 105 NLKS---KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
L+ K DK K+NS L+ NE L++ EL T++E+ +LN +++ +V
Sbjct: 639 ALRQEFKKKDKTLKENSRKLEEENENLRA---ELQCCSTQLES-----SLNKYNTSQQV- 689
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDP-YQEDNLKSRDLQKLSISSDNMQ 220
I L +E+ L ++ L+ +L KA Q + Y + + LS S Q
Sbjct: 690 -------IQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 742
Query: 221 HAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKA 256
+L + + L+ VT + + L++ T T KKA
Sbjct: 743 D---DLTQALEKLNHVTS-ETKSLQQSLTQTQEKKA 774
Score = 34.3 bits (77), Expect = 0.20
Identities = 61/268 (22%), Positives = 108/268 (40%), Gaps = 50/268 (18%)
Query: 42 VTAYEDIKKRLKD-----SEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY 96
V Y+++ K L+ SE++ +++K ++ LE L EE ++ + R+ +
Sbjct: 322 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMK-LELDLHGLREETSAHIERKDKDITILQC 380
Query: 97 R--EVCID---RDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVM--- 148
R E+ ++ L K DK ++ E L+ L ++L + LL+ E+E QQ M
Sbjct: 381 RLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATE 440
Query: 149 -------------RNLNPPSSNWEVEKLSCDL------------KIHGLEQELELMRKEC 183
+ + EV+KL L + ++E L
Sbjct: 441 LEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHL 500
Query: 184 SDLKIELQKAKQTDPYQEDNLK--SRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQA 241
D + +LQK D + D ++ R+LQ L S + K + SN V ++
Sbjct: 501 EDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAE------KEQTSNRKRVEELSL 554
Query: 242 EL---LRKLKTSTAIKKACAPVGCSEDL 266
EL LRKL+ S K+ +D+
Sbjct: 555 ELSEALRKLENSDKEKRQLQKTVAEQDM 582
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 46.6 bits (109), Expect = 4e-05
Identities = 48/193 (24%), Positives = 90/193 (46%), Gaps = 31/193 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLI---ARFEEETSSVGREQVNKAYHAYREVCID 102
++ +L E++ ++L + L E L A+F E+ EQ+ KA
Sbjct: 829 QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER--EEQLIKAKEKL------ 880
Query: 103 RDNLKSKLDKMNKDNSESLKVLNEQLQSKE--VELLQLRT--------------EVETQQ 146
+N +++ KM+ DNS L +N++L+ KE VE LQL+ E T +
Sbjct: 881 -ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939
Query: 147 VMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKA-KQTDPYQEDNLK 205
++ + E EK + K+ LE+++E +C +LK ++A +T E+ L
Sbjct: 940 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL- 998
Query: 206 SRDLQKLSISSDN 218
++LQK + +++
Sbjct: 999 -QNLQKTLLDTED 1010
Score = 40.4 bits (93), Expect = 0.003
Identities = 63/246 (25%), Positives = 115/246 (46%), Gaps = 48/246 (19%)
Query: 32 DESVASHFALVTAYEDIK----KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGRE 87
+ ++ASH A E++K K L E + LK +I EK+ ++ E ++ +
Sbjct: 582 ETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI----EKMRLDYQHEIENLQNQ 634
Query: 88 QVN-KAYHAYR---------EVCIDRDN----LKSKLDKMNKDN----SESLKVLNE-QL 128
Q + +A HA +V +++N ++SKLDK + ++L L E ++
Sbjct: 635 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 694
Query: 129 QSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI 188
+ KE+E+LQ + +T +V+ N E EKL +L+ +RK S+ K
Sbjct: 695 KVKELEVLQAKCNEQT-KVIDNFTSQLKATE-EKL----------LDLDALRKASSEGKS 742
Query: 189 ELQKAKQTDPYQEDNLKSRDLQKLSISSD------NMQHAYWELKREMSNLHLVTQVQAE 242
E++K +Q E +K +++K + SS +Q +L NL V+QV+
Sbjct: 743 EMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKET 802
Query: 243 LLRKLK 248
L ++L+
Sbjct: 803 LEKELQ 808
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)
Query: 63 KKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK 122
++ I L+E AR EET ++++ Y A ++ + ++LKSKL+ NK+NS+ +
Sbjct: 521 QREITSLKEHFGAR--EETH---QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 575
Query: 123 VLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNW-----EVEKLSCDL--KIHGLEQE 175
+ +L++ Q E++ + L ++ + ++EK+ D +I L+ +
Sbjct: 576 LWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ 634
Query: 176 LELMR----KECSDLKIELQK 192
+ R KE L+ +L K
Sbjct: 635 QDSERAAHAKEMEALRAKLMK 655
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 46.6 bits (109), Expect = 4e-05
Identities = 48/193 (24%), Positives = 90/193 (46%), Gaps = 31/193 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLI---ARFEEETSSVGREQVNKAYHAYREVCID 102
++ +L E++ ++L + L E L A+F E+ EQ+ KA
Sbjct: 864 QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER--EEQLIKAKEKL------ 915
Query: 103 RDNLKSKLDKMNKDNSESLKVLNEQLQSKE--VELLQLRT--------------EVETQQ 146
+N +++ KM+ DNS L +N++L+ KE VE LQL+ E T +
Sbjct: 916 -ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974
Query: 147 VMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKA-KQTDPYQEDNLK 205
++ + E EK + K+ LE+++E +C +LK ++A +T E+ L
Sbjct: 975 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL- 1033
Query: 206 SRDLQKLSISSDN 218
++LQK + +++
Sbjct: 1034 -QNLQKTLLDTED 1045
Score = 40.4 bits (93), Expect = 0.003
Identities = 63/246 (25%), Positives = 115/246 (46%), Gaps = 48/246 (19%)
Query: 32 DESVASHFALVTAYEDIK----KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGRE 87
+ ++ASH A E++K K L E + LK +I EK+ ++ E ++ +
Sbjct: 617 ETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI----EKMRLDYQHEIENLQNQ 669
Query: 88 QVN-KAYHAYR---------EVCIDRDN----LKSKLDKMNKDN----SESLKVLNE-QL 128
Q + +A HA +V +++N ++SKLDK + ++L L E ++
Sbjct: 670 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 729
Query: 129 QSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI 188
+ KE+E+LQ + +T +V+ N E EKL +L+ +RK S+ K
Sbjct: 730 KVKELEVLQAKCNEQT-KVIDNFTSQLKATE-EKL----------LDLDALRKASSEGKS 777
Query: 189 ELQKAKQTDPYQEDNLKSRDLQKLSISSD------NMQHAYWELKREMSNLHLVTQVQAE 242
E++K +Q E +K +++K + SS +Q +L NL V+QV+
Sbjct: 778 EMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKET 837
Query: 243 LLRKLK 248
L ++L+
Sbjct: 838 LEKELQ 843
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)
Query: 63 KKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK 122
++ I L+E AR EET ++++ Y A ++ + ++LKSKL+ NK+NS+ +
Sbjct: 556 QREITSLKEHFGAR--EETH---QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 610
Query: 123 VLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNW-----EVEKLSCDL--KIHGLEQE 175
+ +L++ Q E++ + L ++ + ++EK+ D +I L+ +
Sbjct: 611 LWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ 669
Query: 176 LELMR----KECSDLKIELQK 192
+ R KE L+ +L K
Sbjct: 670 QDSERAAHAKEMEALRAKLMK 690
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 46.2 bits (108), Expect = 5e-05
Identities = 53/285 (18%), Positives = 130/285 (45%), Gaps = 31/285 (10%)
Query: 6 EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
+ ++ +L+ + HK++ + + AL ++ ++ + SLL++
Sbjct: 1593 QQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE- 1651
Query: 66 IRFLEEKLIARFEEETSSVG--REQVNKAYH----AYREVCIDRDNLKSKLDKMNKDNSE 119
+ F + +L + E + + ++++ K R++ + LK+ LD + +N E
Sbjct: 1652 LSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHE 1711
Query: 120 --SLKVLNEQ----LQSKEVELLQLRTEVETQQVMRNLNPPSSNW----------EVEKL 163
LK+ ++Q L+ +V +L+ + E+E Q + W E+E++
Sbjct: 1712 LQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERM 1771
Query: 164 SCDLK-----IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSR--DLQKLSISS 216
+ + + + L +E E ++++C + +L + K+ E+N K +L+KL ++
Sbjct: 1772 TAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNV 1831
Query: 217 DNMQHAYWELKREMSNLHL-VTQVQAELLRKLKTSTAIKKACAPV 260
+Q +L R+ +LH ++ +Q +L K + ++++ A V
Sbjct: 1832 RKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANV 1876
Score = 40.0 bits (92), Expect = 0.004
Identities = 37/147 (25%), Positives = 69/147 (46%), Gaps = 10/147 (6%)
Query: 110 LDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQ----VMRN---LNPPSSNWEVEK 162
L+K L +QL K ELL L+ E ++ + ++RN + +V
Sbjct: 2016 LEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVAS 2075
Query: 163 LSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHA 222
L LKI + E L+ ++ + I+ + A Q+++ ++R L K + MQ+
Sbjct: 2076 LKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK---ELNQMQYE 2132
Query: 223 YWELKREMSNLHLVTQVQAELLRKLKT 249
Y ELK++M+N + + Q E+ ++T
Sbjct: 2133 YTELKKQMANQKDLERRQMEISDAMRT 2159
Score = 33.9 bits (76), Expect = 0.26
Identities = 38/180 (21%), Positives = 81/180 (45%), Gaps = 25/180 (13%)
Query: 74 IARFEEETSSVGREQVNKAYHAYREVCIDRDNL----KSKLDKMNKDNSESLK---VLNE 126
I + +E+ +G+ + + A ID K + D+ +++ +L+ L+
Sbjct: 378 IDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDT 437
Query: 127 QLQSKE-------VELLQLRTEVET--QQVMR------NLNPPSSNWEVEKLSCDLKIHG 171
QL+ KE L +L E+E QQ++R L ++ + DL
Sbjct: 438 QLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQ 497
Query: 172 LEQELEL---MRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKR 228
L L+L +R+E DL+++++K KQ ++ +K + S+ S + +H++ + ++
Sbjct: 498 LSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQK 557
Score = 32.0 bits (71), Expect = 0.99
Identities = 37/182 (20%), Positives = 78/182 (42%), Gaps = 35/182 (19%)
Query: 15 EKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLI 74
E+ +R T V++ D+ + S A D K + K+ +LK+ K++
Sbjct: 1478 EELERRAQETAVNLVKADQQLRSLQA------DAKDLEQHKIKQEEILKEI-----NKIV 1526
Query: 75 ARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQ---LQSK 131
A + + + +++ ++ + L+ ++ ++ L+VL E LQ+K
Sbjct: 1527 AAKDSDFQCLSKKK--------EKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAK 1578
Query: 132 EVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQ 191
EL +L+++V +QQ E D ++ ++EL L++ K +LQ
Sbjct: 1579 RAELEKLKSQVTSQQ-------------QEMAVLDRQLGHKKEELHLLQGSMVQAKADLQ 1625
Query: 192 KA 193
+A
Sbjct: 1626 EA 1627
Score = 31.2 bits (69), Expect = 1.7
Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 22/225 (9%)
Query: 50 KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSK 109
++L+D E L +R+ +E++ R + E ++ E + K ++ + +
Sbjct: 640 RKLRD---EKETLLQRLTEVEQE---RDQLEIVAMDAENMRKELAELESALQEQHEVNAS 693
Query: 110 LDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK- 168
L + D S L +L ++ E QL+ E+E + L + E+EK LK
Sbjct: 694 LQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKN 753
Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKR 228
G Q E +E S+L +L+ Q+DN + Q+L +++ H L R
Sbjct: 754 ALGKAQFSEEKEQENSELHAKLKH------LQDDNNLLK--QQLKDFQNHLNHVVDGLVR 805
Query: 229 EMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKL 273
V EL RKLK T +P S+ LG+ L
Sbjct: 806 PEE----VAARVDELRRKLKLGTGEMNIHSP---SDVLGKSLADL 843
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 45.8 bits (107), Expect = 7e-05
Identities = 62/250 (24%), Positives = 114/250 (45%), Gaps = 38/250 (15%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEE-ETSSVGREQVNKAYHAYREV 99
L + + K+++++EKE + + RI E K+ + E + + Q+ ++ A E
Sbjct: 611 LESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEE 670
Query: 100 CIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWE 159
+ + K+ +M K++ ++ NE Q+ E ++ Q E +Q+ S E
Sbjct: 671 LVQL-RAQEKVHEMEKEHLNKVQTANEVKQAVEQQI-QSHRETHQKQIS------SLRDE 722
Query: 160 VE---KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISS 216
VE KL DL+ + LE R L++E +K K TD QE KSR L +L++
Sbjct: 723 VEAKAKLITDLQDQNQKMMLEQER-----LRVEHEKLKATD--QE---KSRKLHELTVMQ 772
Query: 217 DNMQHAYWELK-------REMSNLHLVTQV-QAELLRKLKTSTAIKKACAPVGCSEDLGR 268
D + A +LK +E+ LH + ++ +L ++K S I S+D G
Sbjct: 773 DRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEID--------SDDTGG 824
Query: 269 DSTKLHLMNF 278
+ + ++F
Sbjct: 825 SAAQKQKISF 834
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 45.8 bits (107), Expect = 7e-05
Identities = 43/171 (25%), Positives = 82/171 (47%), Gaps = 17/171 (9%)
Query: 48 IKKRLKDSEKENSLLKKRIRFL------EEKLIARFEEETSSVGREQVNKAYHAYREVCI 101
++K+L+D KEN L +++ L + + I + E E + N R
Sbjct: 894 LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY--- 950
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSK---EVELLQLRTEVETQQVMRNLNPPSSNW 158
RD ++ KL K+ K NSE L+ EQ+Q K + E L+ + + T+Q+ ++
Sbjct: 951 -RDAVEEKLAKLQKHNSE-LETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQR 1008
Query: 159 EVEKLSCDLKIHGLEQELELMRKE---CSDLKIELQKAKQTDPYQEDNLKS 206
+ + S +LK E++++ +++E D K++LQ + + D LK+
Sbjct: 1009 MLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKA 1059
Score = 34.3 bits (77), Expect = 0.20
Identities = 28/150 (18%), Positives = 68/150 (45%), Gaps = 18/150 (12%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
D K+++ + EK+ L+ R+ EK+ + EE ++ + R Q +
Sbjct: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQE------------EEGTQ 1260
Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCD 166
+ L+ N+ +++ + L +++Q + L+ + ET+ ++ N+ E
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVK------CNFRQEASRLT 1314
Query: 167 LKIHGLEQELELMRKECSDLKIELQKAKQT 196
L+ LE+EL++ + L+ +++ +T
Sbjct: 1315 LENRDLEEELDMKDRVIKKLQDQVKTLSKT 1344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,627,000
Number of Sequences: 37866
Number of extensions: 727661
Number of successful extensions: 3448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 2669
Number of HSP's gapped (non-prelim): 1059
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.