Search of human proteins with 239756750

Search of human proteins with 239756750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756750 PREDICTED: similar to TBC1 domain family, member
28 [Homo sapiens]
         (234 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756750 PREDICTED: similar to TBC1 domain family, member 28...   479   e-136
gi|151108489 TBC1 domain family, member 28 [Homo sapiens]             420   e-118
gi|148235002 TBC1 domain family, member 26 [Homo sapiens]             359   1e-99
gi|109638751 ubiquitin specific protease 6 [Homo sapiens]             172   2e-43
gi|149999613 TBC1 domain family, member 3B [Homo sapiens]             171   6e-43
gi|90577185 TBC1 domain family member 3C [Homo sapiens]               171   6e-43
gi|157502205 TBC1 domain family, member 3G [Homo sapiens]             171   6e-43
gi|183583565 TBC1 domain family, member 3 [Homo sapiens]              169   1e-42
gi|183583567 TBC1 domain family, member 3E [Homo sapiens]             169   1e-42
gi|183583563 TBC1 domain family, member 3D [Homo sapiens]             169   1e-42
gi|226693407 TBC1 domain family, member 3H [Homo sapiens]             169   2e-42
gi|14149985 TBC1 domain family, member 3F [Homo sapiens]              166   1e-41
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...   140   7e-34
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]              126   1e-29
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]            126   1e-29
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             60   1e-09
gi|13994322 TBC1 domain family, member 10A [Homo sapiens]              60   2e-09
gi|38348348 TBC1 domain family, member 10C [Homo sapiens]              52   4e-07
gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapi...    51   1e-06
gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapi...    49   5e-06
gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapi...    49   5e-06
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]     42   5e-04
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member...    40   0.002
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    39   0.004
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               35   0.072
gi|219555700 leucine rich repeat containing 27 isoform a [Homo s...    34   0.095
gi|55741567 leucine rich repeat containing 27 isoform a [Homo sa...    34   0.095
gi|148806902 TBC1 domain family, member 12 [Homo sapiens]              34   0.12 
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    33   0.16 
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    33   0.16 

>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
           [Homo sapiens]
          Length = 234

 Score =  479 bits (1234), Expect = e-136
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MCPEQPIVGTSPSASGRRLSCQGRMEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLG 60
           MCPEQPIVGTSPSASGRRLSCQGRMEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLG
Sbjct: 1   MCPEQPIVGTSPSASGRRLSCQGRMEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLG 60

Query: 61  HEQVDVRKYTNNLGIVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQ 120
           HEQVDVRKYTNNLGIVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQ
Sbjct: 61  HEQVDVRKYTNNLGIVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQ 120

Query: 121 RVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKH 180
           RVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKH
Sbjct: 121 RVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKH 180

Query: 181 MMFIQRFGVKQQELCDILVAYSAYNPVSIPGQRYSWYLCPYSQAWVSLGGVATS 234
           MMFIQRFGVKQQELCDILVAYSAYNPVSIPGQRYSWYLCPYSQAWVSLGGVATS
Sbjct: 181 MMFIQRFGVKQQELCDILVAYSAYNPVSIPGQRYSWYLCPYSQAWVSLGGVATS 234


>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
          Length = 210

 Score =  420 bits (1079), Expect = e-118
 Identities = 207/210 (98%), Positives = 207/210 (98%)

Query: 25  MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
           MEMD DP NLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELP V
Sbjct: 1   MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60

Query: 85  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 144
           SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI
Sbjct: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120

Query: 145 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 204
           KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180

Query: 205 NPVSIPGQRYSWYLCPYSQAWVSLGGVATS 234
           NPVSIPGQRYSWYLCPYSQAWVSLGGVATS
Sbjct: 181 NPVSIPGQRYSWYLCPYSQAWVSLGGVATS 210


>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
          Length = 250

 Score =  359 bits (921), Expect = 1e-99
 Identities = 178/182 (97%), Positives = 179/182 (98%)

Query: 25  MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
           MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELP V
Sbjct: 1   MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60

Query: 85  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 144
           SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRV KVIPLAVRGRA SLLLDID+I
Sbjct: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120

Query: 145 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 204
           KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180

Query: 205 NP 206
           NP
Sbjct: 181 NP 182


>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
          Length = 1406

 Score =  172 bits (437), Expect = 2e-43
 Identities = 89/182 (48%), Positives = 124/182 (68%), Gaps = 1/182 (0%)

Query: 25  MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
           M+M  +  +L AQ + +I++ KY++GHRAG   D G E V +    +  GI+HE ELP V
Sbjct: 1   MDMVENADSLQAQERKDILM-KYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPV 59

Query: 85  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 144
           +A E K+ R+E  RT+KW +ML +W  Y+ + KL  RV K IP+ +RG   S+LL+I +I
Sbjct: 60  TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119

Query: 145 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 204
           K +NPG+Y++MKE+GKRSS  IH I LDV  TL+ H+ F  R+G KQ+EL  IL+AYS Y
Sbjct: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179

Query: 205 NP 206
           NP
Sbjct: 180 NP 181


>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
          Length = 549

 Score =  171 bits (432), Expect = 6e-43
 Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
          Length = 549

 Score =  171 bits (432), Expect = 6e-43
 Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
          Length = 549

 Score =  171 bits (432), Expect = 6e-43
 Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
          Length = 549

 Score =  169 bits (429), Expect = 1e-42
 Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
          Length = 549

 Score =  169 bits (429), Expect = 1e-42
 Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
          Length = 549

 Score =  169 bits (429), Expect = 1e-42
 Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
          Length = 549

 Score =  169 bits (428), Expect = 2e-42
 Identities = 88/167 (52%), Positives = 115/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GH+AG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHQAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
          Length = 549

 Score =  166 bits (421), Expect = 1e-41
 Identities = 87/167 (52%), Positives = 114/167 (68%), Gaps = 5/167 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW  ML DW KY+S++KL  R  K +P+ +RG   S+LL+ +++K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           K+SS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNP
Sbjct: 136 KKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNP 182


>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score =  140 bits (354), Expect = 7e-34
 Identities = 73/149 (48%), Positives = 102/149 (68%), Gaps = 5/149 (3%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNNL---GIVHEMELPHVSALEVKQRRKESKRT 99
           II KYE+GHRAG   D G +      Y NN+   G+ HE ELP ++A EVKQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPFG--SYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75

Query: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
           +KW KML +W  Y++++KL  R  + IP+ +RG   S+LL+I++IK +NPG+Y++MKEKG
Sbjct: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135

Query: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFG 188
           KRSS  I  + LDVS TL++H+ F  R+G
Sbjct: 136 KRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164


>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
          Length = 828

 Score =  126 bits (317), Expect = 1e-29
 Identities = 70/165 (42%), Positives = 99/165 (60%), Gaps = 4/165 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVD--VRKYTNNLGIVHEMELPHVSALEVKQRRKESKRTN 100
           I+ KY++G R GA ++   E  D  V K T+  G +HE ELP  +    +Q+  E +RT 
Sbjct: 18  IVAKYDRG-REGAEIE-PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTT 75

Query: 101 KWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKGK 160
           KW KML  W KY++T+K  +R+ K IPL +RG   +LLL+I K+K +    Y  +K + +
Sbjct: 76  KWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRAR 135

Query: 161 RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYN 205
             S  I  I LDV+ T + H+MF  R+GVKQQ L  +L AYS YN
Sbjct: 136 GCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN 180


>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
          Length = 845

 Score =  126 bits (317), Expect = 1e-29
 Identities = 70/165 (42%), Positives = 99/165 (60%), Gaps = 4/165 (2%)

Query: 43  IITKYEQGHRAGAAVDLGHEQVD--VRKYTNNLGIVHEMELPHVSALEVKQRRKESKRTN 100
           I+ KY++G R GA ++   E  D  V K T+  G +HE ELP  +    +Q+  E +RT 
Sbjct: 35  IVAKYDRG-REGAEIE-PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTT 92

Query: 101 KWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKGK 160
           KW KML  W KY++T+K  +R+ K IPL +RG   +LLL+I K+K +    Y  +K + +
Sbjct: 93  KWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRAR 152

Query: 161 RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYN 205
             S  I  I LDV+ T + H+MF  R+GVKQQ L  +L AYS YN
Sbjct: 153 GCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN 197


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 3/112 (2%)

Query: 97  KRTNKWQKMLADWTKYRSTK--KLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKV 154
           +R  KW  M ++W K+ S +  K+  R  K IP ++R +A   L +  ++  QNPGK++ 
Sbjct: 330 QRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEE 389

Query: 155 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           + E+     + +  I+ D+      H MF  R G  QQ+L  IL AY+ Y P
Sbjct: 390 L-ERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRP 440


>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
          Length = 508

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 3/112 (2%)

Query: 97  KRTNKWQKMLADWTKY--RSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKV 154
           +R +KW  ML +W K+  +  KK+  R  K IP ++RGRA   L        QNPGK+  
Sbjct: 81  QRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDE 140

Query: 155 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           + +      + +  I+ D+      H MF+ R G  QQ+L  +L AY+ Y P
Sbjct: 141 L-DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRP 191


>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
          Length = 446

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 3/112 (2%)

Query: 97  KRTNKWQKMLADWTKYRST--KKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKV 154
           +R  KW +M + W K  S   KK+  +  K IP A+R R   LL      +  +PG Y+ 
Sbjct: 62  QREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQE 121

Query: 155 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           + E      + +  I  D+      H MF+   G  QQ L  +L AY+ Y P
Sbjct: 122 LAE-APGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRP 172


>gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 617

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 20/87 (22%)

Query: 19  LSCQGRMEMDGDPYNLPAQGQGNIIITKYEQGHRAGAA-----------------VDLGH 61
           LSC  RMEMD  P  LP QGQGNIIITKYEQ HR                       LGH
Sbjct: 33  LSC--RMEMDEHPDILPTQGQGNIIITKYEQDHRVKTGSPCRQDPKPFTLPLSPWPSLGH 90

Query: 62  EQVDV-RKYTNNLGIVHEMELPHVSAL 87
              ++ +++T ++ ++     P VS L
Sbjct: 91  RDAELGQQWTQSMSVLTSGNSPVVSGL 117


>gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo
          sapiens]
          Length = 339

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 31/75 (41%), Positives = 37/75 (49%), Gaps = 8/75 (10%)

Query: 25 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
          MEMD  P  LP QGQGNIIITKYEQG +A     +G             G      + H+
Sbjct: 1  MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGR--------CRRPGSSANSIMAHL 52

Query: 85 SALEVKQRRKESKRT 99
          +A EV   R  S+ T
Sbjct: 53 TAKEVGYHRDLSRNT 67


>gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo
          sapiens]
          Length = 339

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 31/75 (41%), Positives = 37/75 (49%), Gaps = 8/75 (10%)

Query: 25 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
          MEMD  P  LP QGQGNIIITKYEQG +A     +G             G      + H+
Sbjct: 1  MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGR--------CRRPGSSANSIMAHL 52

Query: 85 SALEVKQRRKESKRT 99
          +A EV   R  S+ T
Sbjct: 53 TAKEVGYHRDLSRNT 67


>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
          Length = 336

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 3/111 (2%)

Query: 96  SKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVM 155
           ++R  KW ++L      RS + + + V K +PL  R R   +L        QNPG Y  +
Sbjct: 40  TRRAIKWSRLLQGGGVPRS-RTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQL 98

Query: 156 KEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFG-VKQQELCDILVAYSAYN 205
            + G+R+ R+   I+ D++ T   ++ F +      Q+ L ++L+AY  +N
Sbjct: 99  LQ-GERNPRLEDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHN 148


>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
           [Homo sapiens]
          Length = 1168

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 99  TNKWQKMLADWTKYR---STKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVM 155
           T  W+KML+   + +     +K+   V + +P   RG     L +   +K Q P K +  
Sbjct: 771 TTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPK 830

Query: 156 ----KEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYS 202
               KE  K+ +   H I +D+  T   H  F  + G  Q  L +IL AYS
Sbjct: 831 DVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYS 881


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 94  KESKRTNKWQKMLADWTK----YRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNP 149
           KE  +   W+   A++ +    YR T+K  + V K IP ++RG    LL      K+ +P
Sbjct: 481 KEFLKEQAWKIHFAEYGQGICMYR-TEKTRELVLKGIPESMRGELWLLLSGAINEKATHP 539

Query: 150 GKYKVMKEKGK-RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           G Y+ + EK   + +     I+ D+  +L +H  F    G+    L  +L AY+  NP
Sbjct: 540 GYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGI--AALRRVLTAYAFRNP 595


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 34.7 bits (78), Expect = 0.072
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 115 TKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKY-KVMKEKGKRSSRIIHCIQLDV 173
           T+K+ + V   IP ++RGR   L  D     + +PG Y  +++E   +   +   I+ D+
Sbjct: 495 TEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDL 554

Query: 174 SHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
             +L +H  F    G+    L  +L AY+  NP
Sbjct: 555 HRSLPEHPAFQNETGI--AALRRVLTAYAHRNP 585


>gi|219555700 leucine rich repeat containing 27 isoform a [Homo
           sapiens]
          Length = 530

 Score = 34.3 bits (77), Expect = 0.095
 Identities = 25/109 (22%), Positives = 58/109 (53%), Gaps = 13/109 (11%)

Query: 80  ELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIP-----LAVRGRA 134
           EL    AL ++Q+R+E +   +W++      + +  +K  + + K++P     +A +  +
Sbjct: 345 ELQEKQAL-MEQQRREKRALQEWRE------RAQRMRKRKEELSKLLPPRRSMVASKIPS 397

Query: 135 LSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQ-LDVSHTLQKHMM 182
            + L+D  K+    PGK K  KEK  ++S+ +  +Q  ++   +++H++
Sbjct: 398 ATDLIDNRKVPLNPPGKMKPSKEKSPQASKEMSALQERNLEEKIKQHVL 446


>gi|55741567 leucine rich repeat containing 27 isoform a [Homo
           sapiens]
          Length = 530

 Score = 34.3 bits (77), Expect = 0.095
 Identities = 25/109 (22%), Positives = 58/109 (53%), Gaps = 13/109 (11%)

Query: 80  ELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIP-----LAVRGRA 134
           EL    AL ++Q+R+E +   +W++      + +  +K  + + K++P     +A +  +
Sbjct: 345 ELQEKQAL-MEQQRREKRALQEWRE------RAQRMRKRKEELSKLLPPRRSMVASKIPS 397

Query: 135 LSLLLDIDKIKSQNPGKYKVMKEKGKRSSRIIHCIQ-LDVSHTLQKHMM 182
            + L+D  K+    PGK K  KEK  ++S+ +  +Q  ++   +++H++
Sbjct: 398 ATDLIDNRKVPLNPPGKMKPSKEKSPQASKEMSALQERNLEEKIKQHVL 446


>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
          Length = 775

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 29/155 (18%)

Query: 78  EMELPHVSALEVKQRRKESKRTNK----W-QKMLADWTKYRSTKKLSQRVCKVIPLAVRG 132
           E++  H     +K+R K+ +        W  ++L +W   RST+++ +   + +P +VRG
Sbjct: 432 EIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRG 491

Query: 133 RALSLLLDIDKIKSQNPGKYKVM----KEKGKRSSRI-----------------IHCIQL 171
           +  SL   +    +  P  Y++     KE+ K  S                   +  I+L
Sbjct: 492 KVWSLA--VGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIKL 549

Query: 172 DVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
           D+S T     +F Q+ G     L  IL AY+ Y P
Sbjct: 550 DISRTFPSLYIF-QKGGPYHDVLHSILGAYTCYRP 583


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 10/136 (7%)

Query: 75  IVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRS---TKKLSQRVCKVIPLAVR 131
           + H   L  +++  +K++ KE      W+ + A+  +  S   TKK    V + IP  +R
Sbjct: 438 VFHPQNLETLNSKMLKEKMKEQS----WKILFAECGRGVSMFRTKKTRDLVVRGIPETLR 493

Query: 132 GRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRI-IHCIQLDVSHTLQKHMMFIQRFGVK 190
           G    L        + NP  Y  + E+   +  +    I+ D+  +L +H  F    G+ 
Sbjct: 494 GELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGI- 552

Query: 191 QQELCDILVAYSAYNP 206
              L  +L AY+  NP
Sbjct: 553 -SALRRVLTAYAYRNP 567


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 10/136 (7%)

Query: 75  IVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRS---TKKLSQRVCKVIPLAVR 131
           + H   L  +++  +K++ KE      W+ + A+  +  S   TKK    V + IP  +R
Sbjct: 438 VFHPQNLETLNSKMLKEKMKEQS----WKILFAECGRGVSMFRTKKTRDLVVRGIPETLR 493

Query: 132 GRALSLLLDIDKIKSQNPGKYKVMKEKGKRSSRI-IHCIQLDVSHTLQKHMMFIQRFGVK 190
           G    L        + NP  Y  + E+   +  +    I+ D+  +L +H  F    G+ 
Sbjct: 494 GELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGI- 552

Query: 191 QQELCDILVAYSAYNP 206
              L  +L AY+  NP
Sbjct: 553 -SALRRVLTAYAYRNP 567


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,277,443
Number of Sequences: 37866
Number of extensions: 385459
Number of successful extensions: 912
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 864
Number of HSP's gapped (non-prelim): 52
length of query: 234
length of database: 18,247,518
effective HSP length: 99
effective length of query: 135
effective length of database: 14,498,784
effective search space: 1957335840
effective search space used: 1957335840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.