Search of human proteins with 239755589

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]
         (356 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]           751   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   4e-09
gi|40353727 synaptopodin isoform A [Homo sapiens]                      60   4e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    53   5e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          52   8e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          52   8e-07
gi|157785645 SPEG complex locus [Homo sapiens]                         52   8e-07
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    51   1e-06
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    51   1e-06
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is...    51   2e-06
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       50   2e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    50   2e-06
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      50   3e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     50   4e-06
gi|156938257 leucine rich repeat containing 16B [Homo sapiens]         50   4e-06
gi|54860079 nadrin isoform 1 [Homo sapiens]                            49   5e-06
gi|54860105 nadrin isoform 2 [Homo sapiens]                            49   5e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         49   5e-06
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      49   7e-06
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      49   7e-06
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       49   7e-06
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       48   1e-05
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         48   1e-05
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    48   1e-05
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    48   1e-05
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      48   2e-05
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       47   2e-05
gi|239755304 PREDICTED: hypothetical protein XP_002344521 [Homo ...    47   3e-05

>gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 356

 Score =  751 bits (1940), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MITLSSSHVQFEEAGLRGAWLIFFFFFFFLVKRHDLIYQFLGNTLWEEGRQRPPETLQPP 60
           MITLSSSHVQFEEAGLRGAWLIFFFFFFFLVKRHDLIYQFLGNTLWEEGRQRPPETLQPP
Sbjct: 1   MITLSSSHVQFEEAGLRGAWLIFFFFFFFLVKRHDLIYQFLGNTLWEEGRQRPPETLQPP 60

Query: 61  ANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQR 120
           ANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQR
Sbjct: 61  ANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQR 120

Query: 121 RRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAE 180
           RRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAE
Sbjct: 121 RRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAE 180

Query: 181 PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSS 240
           PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSS
Sbjct: 181 PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSS 240

Query: 241 ELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMG 300
           ELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMG
Sbjct: 241 ELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMG 300

Query: 301 PWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSSRRR 356
           PWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSSRRR
Sbjct: 301 PWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSSRRR 356


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 89/329 (27%), Positives = 112/329 (34%), Gaps = 44/329 (13%)

Query: 49  GRQRPPETLQPPANR---GGGPVGAPRVSRRREGLRALKVPGSEPQVGA--EVRPSSRKS 103
           G  RPP  + P A R     G VG   ++ R  G+    +P S P+ G       SSR  
Sbjct: 31  GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNP 90

Query: 104 LSDHRGLGRGRRRRRQR-----------RRWGTQAPCGRL--------------RAKPAL 138
            S     GRG R    +           R  GT  P G L              R K   
Sbjct: 91  ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP-GPLGQKGLRISAEETVARGKATE 149

Query: 139 QTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKP 198
             +R       +R     +P   S   +  S   G   G   P    +P A P PP   P
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP----APSARPRPPTEGP 205

Query: 199 GSPTQRAREASSWKP-PGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLS 257
                 A E S+ +P P        G G QRP   R  S S++ LSS A  G     T  
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRP-ASRSLSSSATPLSSPARSGPSARGT-- 262

Query: 258 PGQRLPT-PPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGP 316
              R P  P  P P  L +   PQ       +  A AL   +  P    + S T   P P
Sbjct: 263 --PRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPSPSGTKARPVP 318

Query: 317 GPHPRSRPTPPRLPYPRRAAGTVGIGRPS 345
            P   + P P  LP     A  + +  PS
Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPS 347



 Score = 35.8 bits (81), Expect = 0.060
 Identities = 55/196 (28%), Positives = 65/196 (33%), Gaps = 23/196 (11%)

Query: 179 AEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRG---TQRPLTQRHS 235
           A PP   S   PP  PPP    P Q      +  P   S T PP         PL    S
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771

Query: 236 SESSSELSSSAWPGTIWTSTLS--PGQRLPTPPPPDPAAL---TSWGLPQQQGAC----V 286
             +S  +S  A P       L+  P Q LP+PP   P       S  LP    A      
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831

Query: 287 PEGIALALRCRAMGPWEEQNWSATSGSPGPGPH-----PR----SRPTPPRLPYPRRAAG 337
           P  +A  L      P       A    P PGP      PR      P PP  P P R+  
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP--PPPSRSPS 889

Query: 338 TVGIGRPSRGPGGSSS 353
           +   G    G   S++
Sbjct: 890 STLSGPDLAGHSSSAT 905



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 68/292 (23%), Positives = 96/292 (32%), Gaps = 19/292 (6%)

Query: 47  EEGRQRPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGS----EPQVGAEVRPSSRK 102
           E G  RP      P+ R   P   PR S       +   P       P  G  ++  + +
Sbjct: 186 EVGLPRPA-----PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 103 SLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFS 162
           SLS          R     R   +AP    + KP      + P V   R     +    S
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 163 SRHSSISEGEGDRCGFAEPPGGSSPPAPP-LPPPPKPGSPTQRAREASSWKPPGHSHTAP 221
           S   +     G +     PP  ++ P P  LPP P   +P   A  + S  P   +  +P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360

Query: 222 PGR-GTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQ 280
           P    +Q P +       +     +  P  +  S  SP  +     PP P AL+S     
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ----APPSPLALSSLQATT 416

Query: 281 QQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYP 332
             G+   +     L    M P + Q  S TS S      P S P    L  P
Sbjct: 417 SLGSPTLQATHSFL---TMSPRQTQA-SLTSPSRPASTPPDSPPLQAPLSLP 464



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 32/108 (29%), Positives = 39/108 (36%), Gaps = 8/108 (7%)

Query: 185 SSPPAPPLPPPPKPGSPTQRAREASSWKPPGH---SHTAPPGRGTQRPLTQRH--SSESS 239
           SS   PPL        P+ +   AS   PP     S   PP +    PLT  H  +    
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP 564

Query: 240 SELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVP 287
           +     A P  + T        + TPPP  P AL S   P  QG   P
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS---PPLQGLPSP 609



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 52/201 (25%), Positives = 62/201 (30%), Gaps = 33/201 (16%)

Query: 179 AEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRG---TQRPLTQRHS 235
           A PP   S   P   PP     P Q      +  P   S T PP         PL    S
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740

Query: 236 SESSSELSSSAWPGTIWTSTL-SPGQRLPTPPP----------PDPAALTSWGLPQQQGA 284
             +S  +S SA P       L +P  ++P  PP          P P A  +   P  Q  
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ-- 798

Query: 285 CVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPH---------PRSRPTPPRLPYPRRA 335
            +P   A         P      S  +  P   P          P S P  P L  PRR 
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 858

Query: 336 AGTVGIGRPSRGPGGSSSRRR 356
                   P+ GP  S S  R
Sbjct: 859 --------PTPGPDTSVSGPR 871



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 39/155 (25%), Positives = 56/155 (36%), Gaps = 12/155 (7%)

Query: 181 PPGGSSPPAPPLPPPPKP--GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSES 238
           PP  +SPP   LP PP     +P  +A    +  PP  +  +PP      PL    S ++
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLA-LPPLQAPPSPPASPPLSPLA-TPSPQA 652

Query: 239 SSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRA 298
            + L+        ++   SP  + P  PP  P    S   P Q     P  +A       
Sbjct: 653 PNALAVHLLQAP-FSPPPSPPVQAPFSPPASPPVSPSATPPSQ----APPSLAAPPLQVP 707

Query: 299 MGPWEEQNWSATSGSPGPGPHPRSRP---TPPRLP 330
             P      S ++  P   P P + P    PP  P
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 79/293 (26%), Positives = 106/293 (36%), Gaps = 46/293 (15%)

Query: 71  PRVSRRREGLR------ALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQRRRWG 124
           PR SR   GL       +L+     P  G ++ P S                    R W 
Sbjct: 614 PRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPS------------------RAW- 654

Query: 125 TQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWF--SSRHSSISEGEGDRCGFAEPP 182
             +P  +   +P+  T+        +R  L +SP W   +SR  S  +G     G  EP 
Sbjct: 655 --SPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSP-GPWEPG 711

Query: 183 GGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSEL 242
            GSS  +PP  PPP P SP+   R  S  +P   +   PP R  Q  L +   + +  + 
Sbjct: 712 RGSSMSSPPPLPPPPPMSPSWSERSVSPLRP--ETEARPPSRQLQALLARNIINAARRKS 769

Query: 243 SSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQ--QQGACVPEGIALALRCRAMG 300
           +S    G       SP  R P PPPP P        PQ  + G+    G A A   R+  
Sbjct: 770 ASPRSAGAENPRPFSP-PRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPL 828

Query: 301 PWEEQNWSATSGSPGPGPHPRS-RPTPPRLPYPRRAAGTVGIGRPSRGPGGSS 352
           P            P     PRS  P PPR    RR+     +   S   G  S
Sbjct: 829 P----------AGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAKS 871



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 50/201 (24%), Positives = 71/201 (35%), Gaps = 55/201 (27%)

Query: 182 PGGSSPPAPPLPPPPK--PG---SPTQRAREASSWKPPGHSHTAPPG-------RGTQRP 229
           P G+ PP+P LP P +  PG   SP Q + + ++  PP     +P         R  Q P
Sbjct: 603 PKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAP 662

Query: 230 ---LTQRHSSESSSELSSSAWPGTIWT-----------STLSPG---------QRLPTPP 266
               + R++   + +   S      WT             +SPG            P P 
Sbjct: 663 RPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPL 722

Query: 267 PPDPAALTSWG---------------LPQQQGACVPEGIALALRCRAMGPWEEQNWSATS 311
           PP P    SW                  +Q  A +   I  A R ++  P      SA +
Sbjct: 723 PPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASP-----RSAGA 777

Query: 312 GSPGPGPHPRSRPTPPRLPYP 332
            +P P   PR+ P PP  P P
Sbjct: 778 ENPRPFSPPRAPPPPPPPPPP 798


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 89/328 (27%), Positives = 112/328 (34%), Gaps = 55/328 (16%)

Query: 49  GRQRPPETLQPPANR---GGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLS 105
           G  RPP  + P A R     G VG   ++ R  G+    +P S P+ G     +SR   S
Sbjct: 31  GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT--RTSRPPAS 88

Query: 106 DHRGLGRGRRRRRQR-----------RRWGTQAPCGRL--------------RAKPALQT 140
                GRG R    +           R  GT  P G L              R K     
Sbjct: 89  -----GRGERAPPAKNTSPGPVSSPGRASGTTRP-GPLGQKGLRISAEETVARGKATEAP 142

Query: 141 QRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKPGS 200
           +R       +R     +P   S   +  S   G   G   P    +P A P PP   P  
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP----APSARPRPPTEGPRK 198

Query: 201 PTQRAREASSWKP-PGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPG 259
               A E S+ +P P        G G QRP   R  S S++ LSS A  G     T    
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRP-ASRSLSSSATPLSSPARSGPSARGT---- 253

Query: 260 QRLPT-PPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGP 318
            R P  P  P P  L +   PQ      P   A      A+GP      +  S S  P P
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQ---VTPPRKDA----APALGPLSSSPLATPSPSAPPSP 306

Query: 319 H-PRSRPTPPRLPYPRRAAGTVGIGRPS 345
             P S  T P  P    +  T  +G P+
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPT 334



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 48/156 (30%), Positives = 57/156 (36%), Gaps = 31/156 (19%)

Query: 179 AEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSES 238
           A PP   S   PP  PPP    P Q A      KPP     APP   T  PL    S  +
Sbjct: 448 ASPPMSPSATPPPQAPPPLAAPPLQLA------KPPPQ---APPALATP-PLQALPSPPA 497

Query: 239 SSELSSSAWPGTIWTSTLSPGQRLP-----TPPPPDPAALTSWGLPQQQGACVPEGIALA 293
           S       +PG    +  SP   LP     TPPP  P  L +  L  Q     P    L 
Sbjct: 498 S-------FPG---QAPFSPSASLPMSPLATPPPQAPPVLAAPLL--QVPPSPPASPTLQ 545

Query: 294 LRCRAMGPWEEQNWS----ATSGSPGPGPHPRSRPT 325
              R   P  + + S      + +PGP P P   P+
Sbjct: 546 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 581



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 66/278 (23%), Positives = 86/278 (30%), Gaps = 56/278 (20%)

Query: 52  RPP-----ETLQPPANRGGGPVGAP-RVSRRRE----GLRALKVPGSEPQV-GAEVRPSS 100
           RPP     E   P  N   GPV +P R S        G + L++   E    G       
Sbjct: 84  RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143

Query: 101 RKSLS-----DHRGLGRG-------RRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVF 148
           R +LS     D  G   G       RR R      G   P    R +P  +  RK     
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203

Query: 149 TQRSLLHSSP-----------------RWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPP 191
           ++ S    SP                 R  SS  + +S            P   + P+ P
Sbjct: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 263

Query: 192 LP------------PPPKPGSPTQRAREASSWKPPGHSH----TAPPGRGTQRPLTQRHS 235
            P            PP K  +P      +S    P  S     +APP   T         
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323

Query: 236 SESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAAL 273
           S++++ L S     T       P   L TPPP  P AL
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 42/157 (26%), Positives = 57/157 (36%), Gaps = 12/157 (7%)

Query: 134 AKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLP 193
           A P+LQT    P     ++          + HS +          A PP   +PPA  LP
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP--LSPLATPPP-QAPPALALP 364

Query: 194 ----PPPKPGSPTQRAREASSWKPPG----HSHTAPPGRGTQRPLTQRHSSESSSELSSS 245
               PP  P SP        S + P     H   AP       P+    S  +S  +S S
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424

Query: 246 AWPGTIWTSTL-SPGQRLPTPPPPDPAALTSWGLPQQ 281
           A P +    +L +P  ++P  PP  P    S   P Q
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 54/191 (28%), Positives = 65/191 (34%), Gaps = 40/191 (20%)

Query: 178 FAEPPGG--SSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHS 235
           F+ PP     +P +PP  PP  P           S  PP     APP      PL    S
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSP-----------SATPPSQ---APPSLAAP-PLQVPPS 445

Query: 236 SESSSELSSSAWPGTIWTSTL-SPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALAL 294
             +S  +S SA P       L +P  +L  PPP  P AL +   P  Q   +P   A   
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT---PPLQ--ALPSPPASFP 500

Query: 295 RCRAMGPWEEQNWSATSGSPGPGPH---------PRSRPTPPRLPYPRRAAGTVGIGRPS 345
                 P      S  +  P   P          P S P  P L  PRR         P+
Sbjct: 501 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--------PT 552

Query: 346 RGPGGSSSRRR 356
            GP  S S  R
Sbjct: 553 PGPDTSVSGPR 563



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 47/197 (23%), Positives = 71/197 (36%), Gaps = 29/197 (14%)

Query: 163 SRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQ-RAREASSWKPPGHSHTAP 221
           ++      G   R   A  PG  +P  P  P PP P +P   R   A+            
Sbjct: 3   NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA------------ 50

Query: 222 PGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSP-----GQRLPTPPPPDPAALTSW 276
            G   ++PL +R      + +  SA P    T T  P     G+R P      P  ++S 
Sbjct: 51  -GAVGRKPLAERAGGIGGATIPESA-PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108

Query: 277 GLPQ---QQGACVPEGIALA-----LRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPR 328
           G      + G    +G+ ++      R +A    +    SA +     GP P   P+P  
Sbjct: 109 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAM 167

Query: 329 LPYPRRAAGTVGIGRPS 345
               R A   VG+ RP+
Sbjct: 168 ARRSRAAGTEVGLPRPA 184



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 17/103 (16%)

Query: 182 PGGSSPPAPPLPPPPKP-GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSS 240
           P   +PP+PP  PP  P  +P+ +A  A +        + PP    Q P     S  +S 
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF----SPPASP 419

Query: 241 ELSSSAWPGTIWTSTLS--PGQRLPTPP----------PPDPA 271
            +S SA P +    +L+  P Q  P+PP          PP  A
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 53/193 (27%), Positives = 73/193 (37%), Gaps = 35/193 (18%)

Query: 181 PPGGSSPPAPPLPPPP------KPGSPTQRAREASSWKPPGH------SHTAPPGRGTQR 228
           P  G S P PP+PPPP      +P       ++    +PP H          PP + + +
Sbjct: 49  PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108

Query: 229 PLTQRHSSE-----SSSELSSSAWPGTIWTSTLSPGQR---LPTPPPPDPAALTSWGLPQ 280
           P+  +         S+   SSSA P T  TS   PG      PTPPP   +A      P 
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPT 168

Query: 281 QQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTP-----PRLPYPRRA 335
              + VP         +A GP         +  PGPGP P+  P P      ++P   + 
Sbjct: 169 PPSSGVP-----TTPPQAGGP-----PPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218

Query: 336 AGTVGIGRPSRGP 348
            G  G+  P   P
Sbjct: 219 GGGPGLSTPGGHP 231



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 54/207 (26%), Positives = 61/207 (29%), Gaps = 73/207 (35%)

Query: 171 GEGDRCGFAEPPGGSSPPAPP----LPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGT 226
           G     G A P   S+PPA P     PP   PG PT     A +  PPG     PP  G 
Sbjct: 116 GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG-PTPTPPPAVTSAPPGAPPPTPPSSGV 174

Query: 227 QRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACV 286
             P T   +                              PPP PAA+   G   +QG   
Sbjct: 175 --PTTPPQAG----------------------------GPPPPPAAVPGPGPGPKQGP-- 202

Query: 287 PEGIALALRCRAMGPWEEQNWSATSG-SPGPGP---HPRSRPTPPRLPYPRRAAGTVGIG 342
                        GP   +      G  PG GP    P   P P     P R  G    G
Sbjct: 203 -------------GPGGPKGGKMPGGPKPGGGPGLSTPGGHPKP-----PHRGGGEPRGG 244

Query: 343 R--------------PSRGPGGSSSRR 355
           R              P  GPGG S  +
Sbjct: 245 RQHHPPYHQQHHQGPPPGGPGGRSEEK 271


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 67/253 (26%), Positives = 107/253 (42%), Gaps = 44/253 (17%)

Query: 52  RPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLG 111
           +PP T +PPA     P+G  +   ++ G      P SE Q G        K+L+   G+G
Sbjct: 354 QPPGTTKPPAQ----PLGPAKPPAQQTGSEK---PSSE-QPGP-------KALAQPPGVG 398

Query: 112 RGRRR-----RRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHS 166
           +   +     +   ++ GT  P   L  +P LQ+  K P   T+  +    P    ++ +
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKP---LAQQPGLQSPAKAPGP-TKTPVQQPGPGKIPAQQA 454

Query: 167 SISEGEGDRCGFAEPP----GGSSPP----APPLPPPPKPGSPTQRAREASSWKP----P 214
              +    + G  +PP    G + PP     P  PPP +PGS    +++  S KP    P
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514

Query: 215 GHSHTAPPGRGTQRPLTQ-----RHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPD 269
           G +  +P   G+ +P +Q     + S++  S    SA   T   S    G+ L  PP   
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL-QPPTVS 573

Query: 270 PAAL--TSWGLPQ 280
           P+A    S GLP+
Sbjct: 574 PSAKQPPSQGLPK 586



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 66/311 (21%), Positives = 111/311 (35%), Gaps = 58/311 (18%)

Query: 50  RQRPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRG 109
           +Q+PP+ +      G  P+      +     +  K+    P  G  ++  ++   +DH  
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK 271

Query: 110 LGRGRRRRRQRRRWGTQAPCGRLRA-KPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSI 168
           L   R   R + +   QA   R  + KP+L +  K P+   Q+      P          
Sbjct: 272 LPLQRDASRPQTK---QADIVRGESVKPSLPSPSKPPI---QQPTPGKPP---------- 315

Query: 169 SEGEGDRCGFAEPPGGS-SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQ 227
                     A+ PG   S P P  PP    G     A++  + KPP      PPG  T+
Sbjct: 316 ----------AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP----VQPPGT-TK 360

Query: 228 RPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPP---PDPAALTSWGLPQQQGA 284
            P      ++  ++ + S  P     S+  PG +    PP     PA       P  Q  
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKP-----SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415

Query: 285 CVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGR- 343
             P+ +A           ++    + + +PGP   P  +P P ++P  +   G     + 
Sbjct: 416 GTPKPLA-----------QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464

Query: 344 -----PSRGPG 349
                PS+ PG
Sbjct: 465 GPTKPPSQLPG 475



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 47/146 (32%), Positives = 61/146 (41%), Gaps = 26/146 (17%)

Query: 135  KPALQTQRKEPLVFTQRSLLHSSPR-WFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLP 193
            KPA Q     P V    S L + PR +F S    IS         A+PP    PP PP P
Sbjct: 2371 KPASQLPSGSPSV----SSLPAKPRPFFRSSSLDIS---------AQPPPPPPPPPPPPP 2417

Query: 194  PPPKPGSPTQRAREASSWKP---PGHSHTAPPGRGTQRPLTQRHSS-ESSSELSSSAWPG 249
            PPP P  P       +S KP   P    T      T  PL    ++ E+++ L S+  P 
Sbjct: 2418 PPPPP--PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPV 2475

Query: 250  TIWTSTLSPGQRLPTPPPPDPAALTS 275
            T   +T       P P PP P+++ S
Sbjct: 2476 TRICTT------APPPVPPKPSSIPS 2495



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 55/255 (21%), Positives = 89/255 (34%), Gaps = 45/255 (17%)

Query: 139 QTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKP 198
           Q + K   V T  ++  SSP+    + +S  +    +   ++ P    PP P +  P   
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQ---PQQTSPKKDAAPKQDLSKAPEPKKPP-PLVKQPTLH 713

Query: 199 GSPTQRAREA----SSWKPPGHSHTAPPGRGTQRPLTQ---------RHSSESSSELSSS 245
           GSP+ +A++     S  KP      + P    + P+           + +++  S  S++
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773

Query: 246 AWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQ-------QGACVPEGIALALRCRA 298
             P    +   S  +   TPP    +A  S   P             +P   + +     
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833

Query: 299 MGPW---------------EEQNWSATSGSPGPG--PHPRSRPTPPRLPYPRRAAGTVGI 341
            GP                EE   + T  SP P   P P+  PTPP    PR  AG   +
Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG---PRPTAGQT-V 889

Query: 342 GRPSRGPGGSSSRRR 356
             P + P      RR
Sbjct: 890 PTPQQSPKPQEQSRR 904


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 67/253 (26%), Positives = 107/253 (42%), Gaps = 44/253 (17%)

Query: 52  RPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLG 111
           +PP T +PPA     P+G  +   ++ G      P SE Q G        K+L+   G+G
Sbjct: 354 QPPGTTKPPAQ----PLGPAKPPAQQTGSEK---PSSE-QPGP-------KALAQPPGVG 398

Query: 112 RGRRR-----RRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHS 166
           +   +     +   ++ GT  P   L  +P LQ+  K P   T+  +    P    ++ +
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKP---LAQQPGLQSPAKAPGP-TKTPVQQPGPGKIPAQQA 454

Query: 167 SISEGEGDRCGFAEPP----GGSSPP----APPLPPPPKPGSPTQRAREASSWKP----P 214
              +    + G  +PP    G + PP     P  PPP +PGS    +++  S KP    P
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514

Query: 215 GHSHTAPPGRGTQRPLTQ-----RHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPD 269
           G +  +P   G+ +P +Q     + S++  S    SA   T   S    G+ L  PP   
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL-QPPTVS 573

Query: 270 PAAL--TSWGLPQ 280
           P+A    S GLP+
Sbjct: 574 PSAKQPPSQGLPK 586



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 66/311 (21%), Positives = 111/311 (35%), Gaps = 58/311 (18%)

Query: 50  RQRPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRG 109
           +Q+PP+ +      G  P+      +     +  K+    P  G  ++  ++   +DH  
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK 271

Query: 110 LGRGRRRRRQRRRWGTQAPCGRLRA-KPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSI 168
           L   R   R + +   QA   R  + KP+L +  K P+   Q+      P          
Sbjct: 272 LPLQRDASRPQTK---QADIVRGESVKPSLPSPSKPPI---QQPTPGKPP---------- 315

Query: 169 SEGEGDRCGFAEPPGGS-SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQ 227
                     A+ PG   S P P  PP    G     A++  + KPP      PPG  T+
Sbjct: 316 ----------AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP----VQPPGT-TK 360

Query: 228 RPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPP---PDPAALTSWGLPQQQGA 284
            P      ++  ++ + S  P     S+  PG +    PP     PA       P  Q  
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKP-----SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415

Query: 285 CVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGR- 343
             P+ +A           ++    + + +PGP   P  +P P ++P  +   G     + 
Sbjct: 416 GTPKPLA-----------QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464

Query: 344 -----PSRGPG 349
                PS+ PG
Sbjct: 465 GPTKPPSQLPG 475



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 47/146 (32%), Positives = 61/146 (41%), Gaps = 26/146 (17%)

Query: 135  KPALQTQRKEPLVFTQRSLLHSSPR-WFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLP 193
            KPA Q     P V    S L + PR +F S    IS         A+PP    PP PP P
Sbjct: 2371 KPASQLPSGSPSV----SSLPAKPRPFFRSSSLDIS---------AQPPPPPPPPPPPPP 2417

Query: 194  PPPKPGSPTQRAREASSWKP---PGHSHTAPPGRGTQRPLTQRHSS-ESSSELSSSAWPG 249
            PPP P  P       +S KP   P    T      T  PL    ++ E+++ L S+  P 
Sbjct: 2418 PPPPP--PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPV 2475

Query: 250  TIWTSTLSPGQRLPTPPPPDPAALTS 275
            T   +T       P P PP P+++ S
Sbjct: 2476 TRICTT------APPPVPPKPSSIPS 2495



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 55/255 (21%), Positives = 89/255 (34%), Gaps = 45/255 (17%)

Query: 139 QTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPPPPKP 198
           Q + K   V T  ++  SSP+    + +S  +    +   ++ P    PP P +  P   
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQ---PQQTSPKKDAAPKQDLSKAPEPKKPP-PLVKQPTLH 713

Query: 199 GSPTQRAREA----SSWKPPGHSHTAPPGRGTQRPLTQ---------RHSSESSSELSSS 245
           GSP+ +A++     S  KP      + P    + P+           + +++  S  S++
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773

Query: 246 AWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQ-------QGACVPEGIALALRCRA 298
             P    +   S  +   TPP    +A  S   P             +P   + +     
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833

Query: 299 MGPW---------------EEQNWSATSGSPGPG--PHPRSRPTPPRLPYPRRAAGTVGI 341
            GP                EE   + T  SP P   P P+  PTPP    PR  AG   +
Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG---PRPTAGQT-V 889

Query: 342 GRPSRGPGGSSSRRR 356
             P + P      RR
Sbjct: 890 PTPQQSPKPQEQSRR 904


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 71/295 (24%), Positives = 104/295 (35%), Gaps = 38/295 (12%)

Query: 52  RPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLG 111
           R   +L+ P +  G P G P  S+       L+ PGS  +         R+ L   +   
Sbjct: 431 RKARSLEQPKSERGAPWGTPGASQEE-----LRAPGSVAE---------RRRLFQQKAAS 476

Query: 112 RGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEG 171
              R R++      +    +   +    T R+E LV +  SL  +  R  S R      G
Sbjct: 477 LDERTRQRSPASDLELRFAQELGRIRRSTSREE-LVRSHESLRATLQRAPSPREP----G 531

Query: 172 EGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQR--- 228
           E         P  S   +P    PP P S  +   E    +  G +    PG G Q+   
Sbjct: 532 EPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVR 591

Query: 229 -----PLTQ-RHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQ 282
                PLT+ R   E  S +   A       +   PG++    PP        W  P  +
Sbjct: 592 RRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRK--REPPAQAVRFLPWATPGLE 649

Query: 283 GACVPEGIAL------ALRCRAMGPWEEQNWSA--TSGSPGPGPHPRSRPTPPRL 329
           GA VP+ +        A +    GP E+  W      G+   G   R+RPT P L
Sbjct: 650 GAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPEL 704



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 52/204 (25%), Positives = 70/204 (34%), Gaps = 49/204 (24%)

Query: 179  AEPPGGSSPPAPPL-PPPPKPGS--------PTQRAREASSWKPPGHSHTAPP--GRGTQ 227
            A PP   +  APPL P  P P S        PT  ++  SS K  G     PP   RG Q
Sbjct: 2794 ARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQ 2853

Query: 228  RPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQR-------------------LPTPPPP 268
                   +  S+    S   P  + T T  P                      +  PP P
Sbjct: 2854 AARPAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAP 2913

Query: 269  DPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRS---RPT 325
            +P A      P+      P      +  +++ P +E   S+   SP   P P     R  
Sbjct: 2914 EPPA------PE------PPPEPTKVTVQSLSPAKEV-VSSPGSSPRSSPRPEGTTLRQG 2960

Query: 326  PPRLPY---PRRAAGTVGIGRPSR 346
            PP+ PY     +A G  G+ R  R
Sbjct: 2961 PPQKPYTFLEEKARGRFGVVRACR 2984



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 81/325 (24%), Positives = 111/325 (34%), Gaps = 49/325 (15%)

Query: 70   APRVSRRREGLRALKVPGSEPQVGAEV------RPSSRKSLSDHRG---LGRGRRRRR-- 118
            AP   +      AL  PG EP  GA        R SS +S     G   LGRG  +    
Sbjct: 1979 APSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASV 2038

Query: 119  ---QRRRWGTQAPCGRLRAKPAL-QTQRKEPLVFTQRSLLHSSPR--WFSSRHSSISEGE 172
               QRR   + +P     A+  L + +  + L   ++ LL   P     S     + E  
Sbjct: 2039 ELPQRR---SPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESL 2095

Query: 173  GDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSW--KPPGHSHTA------PPGR 224
            G R         +S  A P   PP      Q++   S    +P G    A      P  R
Sbjct: 2096 GGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVAR 2155

Query: 225  GTQRPLTQRHSSESSSEL--SSSAWPGTIWTSTLSPGQ-------RLPTPPPPDPA---A 272
               R L +  S  + SE   SS A P     ST    +         P PP P PA   A
Sbjct: 2156 LGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKA 2215

Query: 273  LTSWGLPQQQGACVPEGIALALRCRAMGPWEE--QNWSATSGSPGPGPHPRSRPTPPRLP 330
                  P +     P   AL      + P+ +  Q+   +  + GP   P +   PP  P
Sbjct: 2216 PEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAA---PPSEP 2272

Query: 331  YPRRAAGTVGIGRPSRGPGGSSSRR 355
             P  A       R +  P G+  +R
Sbjct: 2273 KPHAAV----FARVASPPPGAPEKR 2293



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 57/214 (26%), Positives = 74/214 (34%), Gaps = 45/214 (21%)

Query: 65   GGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQR-RRW 123
            GG    PR++R      A   P  +P       P   + L       +G    R R RR 
Sbjct: 2096 GGRARDPRMARAASSEAA---PHHQP-------PLENRGLQKSSSFSQGEAEPRGRHRRA 2145

Query: 124  GT--QAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEP 181
            G   + P  RL A+   ++     L   Q S    SP   S+   S  +        AEP
Sbjct: 2146 GAPLEIPVARLGARRLQESPSLSALSEAQPS----SPARPSAPKPSTPKS-------AEP 2194

Query: 182  PGG--SSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQR---PLTQRHSS 236
                 S  P PP P P +  +P  R     + KP      APP +  Q    PLT     
Sbjct: 2195 SATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKP------APPPQALQTLALPLTPYAQI 2248

Query: 237  ESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDP 270
              S +LS  A           P Q  P  PP +P
Sbjct: 2249 IQSLQLSGHA---------QGPSQG-PAAPPSEP 2272



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 8/70 (11%)

Query: 183 GGSSPPAPPLPPPPKPGSPTQRARE--------ASSWKPPGHSHTAPPGRGTQRPLTQRH 234
           G  SPP PP  P   P SP +R +E            +      + P   GT     Q  
Sbjct: 317 GKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAESRPQTP 376

Query: 235 SSESSSELSS 244
            SE+S  LS+
Sbjct: 377 LSEASGRLSA 386



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 48/191 (25%), Positives = 69/191 (36%), Gaps = 34/191 (17%)

Query: 179 AEPPGGSS----PPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRH 234
           A+PP   S    PP+P +     PG P Q A   +S           P R TQ P+    
Sbjct: 299 AQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTS-----------PHRRTQEPVLPED 347

Query: 235 SS--ESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIAL 292
           ++  E   + S S+ P    T+   P     TP       L++ G   +    V  G  +
Sbjct: 348 TTTEEKRGKKSKSSGPSLAGTAESRP----QTPLSEASGRLSALG---RSPRLVRAGSRI 400

Query: 293 ALRCRAMGPWEEQNWSATSGSPGPGP----HPRSRPTPPRLPYPRRAA--GTVGIGRPS- 345
             + +    +EE+  S       P P     P  +      P   R A  GT G  +   
Sbjct: 401 LDKLQF---FEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEEL 457

Query: 346 RGPGGSSSRRR 356
           R PG  + RRR
Sbjct: 458 RAPGSVAERRR 468


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 6/141 (4%)

Query: 188 PAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAW 247
           P PP  PPP+P  P       S++KP        P   +    +   SS SSS  SSS+ 
Sbjct: 62  PGPPPQPPPQPPPPQYDYPPQSTFKPKAE----VPSSSSSSSSSSSSSSSSSSSSSSSSS 117

Query: 248 PGTIWTSTLSPGQRLPTPPPPDPAALT-SWGLPQQQGACVPEGIALALRCRAMGPWEEQN 306
                   L P    P PP  D A  T  WG+    G     G  L     A GP     
Sbjct: 118 QAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFG-NLKRGGPASGPGVTPG 176

Query: 307 WSATSGSPGPGPHPRSRPTPP 327
             A +G+PGP P P   P  P
Sbjct: 177 LGAPAGAPGPLPAPSQTPPGP 197



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 15/41 (36%), Positives = 20/41 (48%)

Query: 313 SPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSS 353
           +PGP P P  +P PP+  YP ++        PS     SSS
Sbjct: 61  APGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSS 101


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 6/141 (4%)

Query: 188 PAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAW 247
           P PP  PPP+P  P       S++KP        P   +    +   SS SSS  SSS+ 
Sbjct: 62  PGPPPQPPPQPPPPQYDYPPQSTFKPKAE----VPSSSSSSSSSSSSSSSSSSSSSSSSS 117

Query: 248 PGTIWTSTLSPGQRLPTPPPPDPAALT-SWGLPQQQGACVPEGIALALRCRAMGPWEEQN 306
                   L P    P PP  D A  T  WG+    G     G  L     A GP     
Sbjct: 118 QAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFG-NLKRGGPASGPGVTPG 176

Query: 307 WSATSGSPGPGPHPRSRPTPP 327
             A +G+PGP P P   P  P
Sbjct: 177 LGAPAGAPGPLPAPSQTPPGP 197



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 15/41 (36%), Positives = 20/41 (48%)

Query: 313 SPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSS 353
           +PGP P P  +P PP+  YP ++        PS     SSS
Sbjct: 61  APGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSS 101


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 50/174 (28%), Positives = 65/174 (37%), Gaps = 66/174 (37%)

Query: 182 PGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGR----------------- 224
           PG   PP PP P PP+PG            + PG+ H  PP                   
Sbjct: 33  PGLRDPP-PPRPAPPRPG------------EEPGNRHPPPPAARTHPGSCRARCPSPAAG 79

Query: 225 GTQRPLTQRHSSESSSELSSSAWPGT--IWTSTL-------SPGQ---RLPTPPPPDPAA 272
           G + P T     + + E +++A P    +W   L       +PG+   RLP PPPP P  
Sbjct: 80  GLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPP-- 137

Query: 273 LTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTP 326
                   ++    P G+A        GP       A S  P P P PRSRP P
Sbjct: 138 --------ERPRLPPAGLA-------GGP-------ADSAPPSPAPAPRSRPAP 169


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 41/158 (25%), Positives = 62/158 (39%), Gaps = 17/158 (10%)

Query: 181 PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQ-RHSSESS 239
           PP    PP PP PPPP P  P+Q A  A S  P    ++          +T+ +++S+ S
Sbjct: 630 PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST---------ITRLQNASQHS 680

Query: 240 SELSSSAWPGTIWTSTLSP-------GQRLPTPPPPDPAALTSWGLPQQQGACVPEGIAL 292
             L     P  + + ++ P       G   P PPPP P    S     +   C P     
Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF 740

Query: 293 ALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLP 330
           +     +   + Q+ +  +    P P P   P PP+ P
Sbjct: 741 SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 39/145 (26%), Positives = 55/145 (37%), Gaps = 41/145 (28%)

Query: 181 PPGGSSPPAPPLPPPPKPGSPTQRAREA---------SSWKPPGHSH-----------TA 220
           PP G  PP PP PPPP PGS   + + A         S+  PP   H           T 
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763

Query: 221 PPGRGTQRPLTQRH------------SSESSSELSSSAWPGTIWTSTLSPGQR------- 261
           PP      PL  +             S+++ + + + A P T  T  + P ++       
Sbjct: 764 PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP-TPPVPPAKKQPAFPAS 822

Query: 262 -LPTPPPPDPAALTSWGLPQQQGAC 285
            +P  PP  P  +    LP+QQ  C
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFC 847



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 37/220 (16%)

Query: 136  PALQTQRKEPLVFT----QRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSS----- 186
            PA+++Q  +P+           + + P+W   + SSI     D   F  PP  SS     
Sbjct: 876  PAMESQPLKPVPANVAPQSPPAVKAKPKW---QPSSIPVPSPD---FPPPPPESSLVFPP 929

Query: 187  -PPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSS 245
             PP+P   PPP P        + S       S T+ PG     P  QR+SS  SS  +  
Sbjct: 930  PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH 989

Query: 246  AWPGTIWTSTL-----------SPGQRLPTPP--PPDPAALTSWG--LP--QQQGACVPE 288
              P      +L           SP +    PP  PP P  L   G  LP   QQG    +
Sbjct: 990  PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049

Query: 289  GIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSR-PTPP 327
               L+ R +       +  S  S S  P P P +  P PP
Sbjct: 1050 APVLSGRGKDS---VVEFPSPPSDSDFPPPPPETELPLPP 1086



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 40/177 (22%), Positives = 58/177 (32%), Gaps = 40/177 (22%)

Query: 182 PGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSE 241
           P    PP+PP PP P P  PT   +++   KPP    +  P       + ++ +S+    
Sbjct: 820 PASYIPPSPPTPPVPVP-PPTLPKQQSFCAKPPPSPLSPVPS------VVKQIASQ---- 868

Query: 242 LSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGP 301
                                  PPPP P A+ S  L        P+        +A   
Sbjct: 869 ----------------------FPPPPTPPAMESQPLKPVPANVAPQSPPAV---KAKPK 903

Query: 302 WEEQNWSATSGSPGPGPHPRSR---PTPPRLPYPRRAAGTVGIGRPSRGPGGSSSRR 355
           W+  +    S    P P P S    P PP  P P           P+    GS  ++
Sbjct: 904 WQPSSIPVPS-PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKK 959



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 44/177 (24%), Positives = 57/177 (32%), Gaps = 25/177 (14%)

Query: 189 APPLPPPPKPGSPTQRAREASSW--KPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSA 246
           APP P PP P +  Q A  AS     PP      PP      P   +  S  +    S  
Sbjct: 802 APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP------PTLPKQQSFCAKPPPSPL 855

Query: 247 WPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQN 306
            P       ++       PPPP P A+ S  L        P+        +A   W+  +
Sbjct: 856 SPVPSVVKQIAS----QFPPPPTPPAMESQPLKPVPANVAPQSPPAV---KAKPKWQPSS 908

Query: 307 WSATSGS-PGPGPH---------PRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSS 353
               S   P P P          P   P PP  P P  +      G P +    +SS
Sbjct: 909 IPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS 965



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 39/168 (23%), Positives = 56/168 (33%), Gaps = 52/168 (30%)

Query: 181 PPGGSSPPAPPLP------------PPPKPGSPTQRA--REASSWKPPGHSHTAPPGRGT 226
           PP   +PP P  P            PPP P SP      + AS + PP      PP   +
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP----PTPPAMES 880

Query: 227 Q--RPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGA 284
           Q  +P+    + +S   + +       W  +  P      PPPP  ++L     P    +
Sbjct: 881 QPLKPVPANVAPQSPPAVKAK----PKWQPSSIPVPSPDFPPPPPESSLV---FPPPPPS 933

Query: 285 CVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYP 332
            VP                         +P P P P + PTP +   P
Sbjct: 934 PVP-------------------------APPPPPPPTASPTPDKSGSP 956



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 43/166 (25%), Positives = 57/166 (34%), Gaps = 27/166 (16%)

Query: 181  PPGGSSPPAPPLPPPPKPGSPTQRAREASSWK--------------PPGHSHTAPPGRGT 226
            PP   S P  P+P    P SP    +    W+              PP  S   PP   +
Sbjct: 875  PPAMESQPLKPVPANVAPQSP-PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPS 933

Query: 227  QRPLTQRHSSESSSEL-SSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGAC 285
              P        ++S     S  PG   + T SPG + P P P   +++ S       GA 
Sbjct: 934  PVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS-----SSGAE 988

Query: 286  VPEGIALALRCRAMGPWEEQNWSATSGSPGPG--PHPRSRPTPPRL 329
             PE      R        +    A SGSP     P P + P P +L
Sbjct: 989  HPE----PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030



 Score = 28.5 bits (62), Expect = 9.6
 Identities = 37/157 (23%), Positives = 48/157 (30%), Gaps = 38/157 (24%)

Query: 197 KPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAWP-GTI---- 251
           K GS +    E+ S     HS+ +  G    +P     S    S + S AW  GT     
Sbjct: 535 KSGSSSSSIPESQS----NHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590

Query: 252 ----WTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNW 307
                 S   P   L  P  P P  +T +   Q      P                    
Sbjct: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPP------------------- 631

Query: 308 SATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRP 344
                 P P P P   P PP  P P ++A + G   P
Sbjct: 632 ------PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 65/233 (27%), Positives = 89/233 (38%), Gaps = 44/233 (18%)

Query: 50  RQRPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRG 109
           +QRPP   Q   +  G P G+P   R       L  P S PQ     +P+S+ +      
Sbjct: 482 QQRPPPQGQQHLSGLGPPAGSPLPQR-------LPSPTSAPQ-----QPASQAAPPTQ-- 527

Query: 110 LGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSIS 169
            G+GR+ R      G   P  R  A P+ Q Q   P    Q S+   +P   S       
Sbjct: 528 -GQGRQSRPVAGGPGA-PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKAS------- 578

Query: 170 EGEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREAS---SWKPPGHSHTAPPGRG- 225
                      PPGG     PP   PP P  PT++A +A       PP      P G G 
Sbjct: 579 ---------GAPPGGQQRQGPP-QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGP 628

Query: 226 TQRP---LTQRHSSESSSELSSSA----WPGTIWTSTLSPGQRLPTPPPPDPA 271
             RP   L Q+ S +     +++A     P    + +L+    LP P PP P+
Sbjct: 629 AGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPS 681



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 54/180 (30%), Positives = 63/180 (35%), Gaps = 14/180 (7%)

Query: 179 AEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSES 238
           A PP    PP    PP P PG   Q         P G  H +  G     PL QR  S +
Sbjct: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512

Query: 239 SS--ELSSSAWPGTIWTSTLS------PGQRLPTPPPPDPAALTSWGLPQQQGACVPEGI 290
           S+  + +S A P T      S      PG      PP  P+     G PQ        G 
Sbjct: 513 SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP 572

Query: 291 ALALRCRAMGPWEEQNWSATSGSPGP-GPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPG 349
           A   +     P  +Q        PGP GP   +R      P PR    T    RPS GPG
Sbjct: 573 A-PPKASGAPPGGQQRQGPPQKPPGPAGP---TRQASQAGPVPRTGPPTTQQPRPS-GPG 627


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 50/170 (29%), Positives = 59/170 (34%), Gaps = 25/170 (14%)

Query: 181 PPGGSSPPAPPLPPPPKP-GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESS 239
           P GG  P  PP  PP KP G P Q  +  SS  PPG     PP  G Q            
Sbjct: 184 PQGGKKPQGPP--PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ------------ 229

Query: 240 SELSSSAWPGTIWTSTLSPGQRLPTPPPP-DPAALTSWGLPQQQGACVPEGIALALRCRA 298
                   PG         G +   PPPP  P    + G  + Q A  P G       + 
Sbjct: 230 -PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG-------KP 281

Query: 299 MGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGP 348
            GP  +Q  +   G P P      +P  P    P+        GRPSR P
Sbjct: 282 QGP-PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 56/189 (29%), Positives = 66/189 (34%), Gaps = 34/189 (17%)

Query: 181 PPGGSSPPAPPLPPPPKP-GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESS 239
           P GG+ P  PP PPP KP G P Q   +     PPG     PP              +S 
Sbjct: 41  PQGGNKPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-----------QGDKSR 88

Query: 240 SELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAM 299
           S  S    P          G   P  PPP P        P  QG   P+G     + +  
Sbjct: 89  SPRSPPGKP----QGPPPQGGNQPQGPPPPPGKPQG---PPPQGGNRPQGPPPPGKPQGP 141

Query: 300 GPWEEQNWSATS--GSP-GPGP----HPRSRPTPPRLPY-PRRAAGTVGIGRPSRG---- 347
            P  +++ S  S  G P GP P     P+  P PP  P  P    G    G P  G    
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201

Query: 348 --PGGSSSR 354
             P G  SR
Sbjct: 202 PPPQGDKSR 210



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 32/122 (26%), Positives = 42/122 (34%), Gaps = 27/122 (22%)

Query: 172 EGDRCGFAE---------PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPP 222
           +GD+   ++         PP G + P  P PPP KP  P  +        PP      PP
Sbjct: 205 QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 264

Query: 223 GRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQ 282
            +G             S   S+ + PG         G     PPPP      + G PQQ 
Sbjct: 265 AQG------------GSKSQSARSPPGKPQGPPQQEGNNPQGPPPP------AGGNPQQP 306

Query: 283 GA 284
            A
Sbjct: 307 QA 308



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 13/43 (30%), Positives = 19/43 (44%)

Query: 172 EGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPP 214
           EG+      PP G +P  P  PP  +P  P +  +     +PP
Sbjct: 288 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 59/195 (30%), Positives = 70/195 (35%), Gaps = 54/195 (27%)

Query: 170 EGEGDRCGFAEPPGGSSPPAPPLPPPPK-----PGSPTQRAREASSWKPPGHSHTAPPGR 224
           +GEG   G A PPGGS P  PP P   K     PG P       ++  P       PPG 
Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP------GAAGFPGARGLPGPPG- 885

Query: 225 GTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGA 284
                              S+  PG    S  SPG+      PP PA  T  G P   G 
Sbjct: 886 -------------------SNGNPGPPGPSG-SPGK----DGPPGPAGNT--GAPGSPGV 919

Query: 285 CVPEGIALALRCRAMGPWEEQNWSATSGSPG-PGP-------HPRSRPTPPRLPYPRRAA 336
             P+G A        G   E+      G PG PGP         R    PP +P PR + 
Sbjct: 920 SGPKGDA--------GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSP 971

Query: 337 GTVGIGRPSRGPGGS 351
           G  G+   S  PG +
Sbjct: 972 GPQGVKGESGKPGAN 986



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 63/213 (29%), Positives = 81/213 (38%), Gaps = 33/213 (15%)

Query: 156 SSPRWFSSRHSSISEGEGDRCG-FAEPPGGSSPPAPPLPP-----PPKPGSPTQRAREAS 209
           + P+ +S ++ S     G   G  A  PG + PP PP PP     P  PGSP  +     
Sbjct: 146 TGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG---- 201

Query: 210 SWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQR-LPTPPP- 267
              PPG    A P  G   P      S  + +   S  PG        PG+R LP PP  
Sbjct: 202 ---PPGEPGQAGPS-GPPGPPGAIGPSGPAGKDGESGRPG-------RPGERGLPGPPGI 250

Query: 268 PDPAALTSWGLPQQQGACVPEG-IALALRCRAMGPWEEQNWSATSGSPGP-----GPHPR 321
             PA +   G P  +G    +G         A G   E      +G+PGP      P  R
Sbjct: 251 KGPAGIP--GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGER 308

Query: 322 SRPTPPRLPYPRRAAGTVGI-GRPS-RGPGGSS 352
            RP  P     R   G  G  G+P   GP G++
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA 341



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 57/203 (28%), Positives = 68/203 (33%), Gaps = 44/203 (21%)

Query: 171  GEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPP--GRGTQR 228
            G+GDR G    PG  +P AP  P PP P  P  ++ +     P G +    P   RG   
Sbjct: 1030 GKGDR-GENGSPG--APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086

Query: 229  PLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPE 288
            P   R     + E  ++   G                 P +P A  S G   QQGA    
Sbjct: 1087 PQGPRGDKGETGERGAAGIKG-------------HRGFPGNPGAPGSPGPAGQQGAIGSP 1133

Query: 289  GIALALRCRAMGPWEEQNWSATSGSPGP--GPHPRSR------------------PTPPR 328
            G A       +GP        TSG PGP   P PR                    P PP 
Sbjct: 1134 GPAGPR--GPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191

Query: 329  LPYP----RRAAGTVGIGRPSRG 347
             P P      AA   GIG    G
Sbjct: 1192 APGPCCGGVGAAAIAGIGGEKAG 1214



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 47/183 (25%), Positives = 56/183 (30%), Gaps = 36/183 (19%)

Query: 181 PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPG------RGTQRPLTQRH 234
           PP G  P  P    P  PG P +        +P       PPG       G Q    Q  
Sbjct: 98  PPNGQGPQGPK-GDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYD 156

Query: 235 SSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALAL 294
           S +  S ++     G        PG   P  PP  P      G P   G           
Sbjct: 157 SYDVKSGVAVGGLAG-------YPGPAGPPGPPGPPGTSGHPGSPGSPG----------- 198

Query: 295 RCRAMGPWEEQNWSATSGSPGP-------GPHPRSRPT-PPRLPYPRRAAGTVGIGRPSR 346
                GP  E   +  SG PGP       GP  +   +  P  P  R   G  GI  P+ 
Sbjct: 199 ---YQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG 255

Query: 347 GPG 349
            PG
Sbjct: 256 IPG 258



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 1/51 (1%)

Query: 300 GPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGG 350
           GP   Q  S   G PGP   PR +P     P P+   G  G      GPGG
Sbjct: 552 GPPGSQGESGRPGPPGPSG-PRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 52/186 (27%), Positives = 65/186 (34%), Gaps = 22/186 (11%)

Query: 179 AEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRP-------LT 231
           A P GG+ P  PP PP    G P Q   +     PP      PP +G  +P         
Sbjct: 39  APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98

Query: 232 QRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIA 291
           Q    +     S  + PG         G + P  PPP P        P  QG   P+G  
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQG---PPPQGGNKPQGPP 154

Query: 292 LALRCRAMGPWEEQNWSATSGSP-----GPGP----HPRSRPTPPRLPY-PRRAAGTVGI 341
              + +   P +  N S +S SP     GP P     P+  P PP  P  P    G    
Sbjct: 155 PPGKPQGPPP-QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 213

Query: 342 GRPSRG 347
           G P  G
Sbjct: 214 GPPPPG 219



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 57/192 (29%), Positives = 69/192 (35%), Gaps = 37/192 (19%)

Query: 181 PPGGSSPPAPPLPPPPKP-GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESS 239
           P GG+ P  PP PPP KP G P Q   +     PPG     PP          +  ++S 
Sbjct: 185 PQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP----------QGDNKSQ 233

Query: 240 SELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAM 299
           S  S    P          G   P  PPP P        P  QG   P+G     + +  
Sbjct: 234 SARSPPGKP----QGPPPQGGNQPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGP 286

Query: 300 GPWEEQNWSATSGSP-----GPGP----HPRSRPTPPRLPY-PRRAAGTVGIGRPSRG-- 347
            P +  + S +S SP     GP P     P+  P PP  P  P    G    G P  G  
Sbjct: 287 PP-QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345

Query: 348 -----PGGSSSR 354
                 GGS SR
Sbjct: 346 QGPPPQGGSKSR 357



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 47/178 (26%), Positives = 63/178 (35%), Gaps = 19/178 (10%)

Query: 181 PPGGSSPPAPPLPPPPKP-GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSE-- 237
           P GG+ P  PP PPP KP G P Q   +     PPG     PP  G++   ++    +  
Sbjct: 247 PQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ 305

Query: 238 ------SSSELSSSAWPGTIWTSTLSPGQRLPTPPPP-DPAALTSWGLPQQQGACVPEGI 290
                  +        PG         G +   PPPP  P      G  + + A  P G 
Sbjct: 306 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPG- 364

Query: 291 ALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGP 348
                 +  GP  +Q  +   G P P      +P  P    P+        GRPSR P
Sbjct: 365 ------KPQGP-PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 62/237 (26%), Positives = 75/237 (31%), Gaps = 56/237 (23%)

Query: 170 EGEGDRCGFAEPPGGSSPPAPP-------LPPPPKP-GSPTQRAREASSWKPPGHSHTAP 221
           +G     G   PPG    P P         PPP KP G P Q  +  S   PPG     P
Sbjct: 63  QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122

Query: 222 PGRGTQ---------RP------------------LTQRHSSESSSELSSSAWPGTIWTS 254
           P  G Q         +P                    Q    +  ++  SS  P      
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182

Query: 255 TLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSP 314
               G   P  PPP P        P  QG   P+G     + +   P +  N S ++ SP
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGPPP-QGDNKSQSARSP 238

Query: 315 -----GPGP----HPRSRPTPPRLPY-PRRAAGTVGIGRPSRG-------PGGSSSR 354
                GP P     P+  P PP  P  P    G    G P  G        GGS SR
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 295



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 13/43 (30%), Positives = 19/43 (44%)

Query: 172 EGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPP 214
           EG+      PP G +P  P  PP  +P  P +  +     +PP
Sbjct: 373 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415


>gi|156938257 leucine rich repeat containing 16B [Homo sapiens]
          Length = 1372

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 81/318 (25%), Positives = 102/318 (32%), Gaps = 82/318 (25%)

Query: 48   EGRQRPPETLQPPANRGGGPVGAPR-----VSRRREGL------RALKVPGSEPQVGAEV 96
            +GR RPP T  P   R   P    R      +R  EGL      R L+   S P+    V
Sbjct: 976  QGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTV 1035

Query: 97   RPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHS 156
            RP          GL              ++AP       P LQ +R+  L   +R     
Sbjct: 1036 RP----------GL--------------SEAPL------PPLQKKRRRGLFHFRR----- 1060

Query: 157  SPRWFSSRHSSISEGEGD-RCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPG 215
             PR F         G G    G   PP    PP P    PP P  P+     +  W P  
Sbjct: 1061 -PRSFKG-----DRGPGSPTTGLLLPP--PPPPPPTQESPPSPDPPSLGNNSSPCWSPEE 1112

Query: 216  HSHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTS 275
             S   P   G + P  +R      SE                PG+  P P       +  
Sbjct: 1113 ESSLLPGFGGGRGPSFRRKMGTEGSE----------------PGEGGPAPGTAQQPRVHG 1156

Query: 276  WGLPQQQGACVPEGIALALRCRAMGPWEE---QNWSATSGSPGPGPHPRSRPTPPRLPYP 332
              LP  + A   +G +   +    GP +E   Q W     S   GP     P PP+   P
Sbjct: 1157 VALPGLERA---KGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKP 1213

Query: 333  -----RRAAGTVGIGRPS 345
                 RRA  T  I   S
Sbjct: 1214 SFSAMRRAEATWHIAEES 1231


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 44/154 (28%), Positives = 54/154 (35%), Gaps = 14/154 (9%)

Query: 188 PAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAW 247
           PAPP P  P PG P  ++   +S  PP  S   PP R    P              S   
Sbjct: 638 PAPPKPGNPPPGHPGGQSSSGTSQHPPSLS-PKPPTRSPSPPTQHTGQPPGQPSAPSQLS 696

Query: 248 PGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNW 307
               ++S+LSP Q    PPP  P   T     +      P  +AL           E   
Sbjct: 697 APRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALP---------SEHGL 747

Query: 308 SATSGSPGPGPHPRSRP----TPPRLPYPRRAAG 337
              S +P   P P S P      P LP P+  AG
Sbjct: 748 EQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 781



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 13/131 (9%)

Query: 156 SSPRWFSSRHSSISEGEGDRCGFAEPPGGSSP---PAPPLPPPPKPGS-PTQRAREASSW 211
           S+PR +SS   S+S  +       +PP  ++P     P    PP P + P++   E  S 
Sbjct: 696 SAPRRYSS---SLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSH 752

Query: 212 KPPGHSHTAP--PGRGTQRP-LTQRHSSESSSELSSSAWPGTIWTS--TLSPGQRLPTPP 266
            PP  + T P  P  G Q P L    +    +  ++    GT+        P  R   PP
Sbjct: 753 TPP-QTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPP 811

Query: 267 PPDPAALTSWG 277
           PP P  + S G
Sbjct: 812 PPQPPGVHSAG 822


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 44/154 (28%), Positives = 54/154 (35%), Gaps = 14/154 (9%)

Query: 188 PAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAW 247
           PAPP P  P PG P  ++   +S  PP  S   PP R    P              S   
Sbjct: 560 PAPPKPGNPPPGHPGGQSSSGTSQHPPSLS-PKPPTRSPSPPTQHTGQPPGQPSAPSQLS 618

Query: 248 PGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNW 307
               ++S+LSP Q    PPP  P   T     +      P  +AL           E   
Sbjct: 619 APRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALP---------SEHGL 669

Query: 308 SATSGSPGPGPHPRSRP----TPPRLPYPRRAAG 337
              S +P   P P S P      P LP P+  AG
Sbjct: 670 EQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 703



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 13/131 (9%)

Query: 156 SSPRWFSSRHSSISEGEGDRCGFAEPPGGSSP---PAPPLPPPPKPGS-PTQRAREASSW 211
           S+PR +SS   S+S  +       +PP  ++P     P    PP P + P++   E  S 
Sbjct: 618 SAPRRYSS---SLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSH 674

Query: 212 KPPGHSHTAP--PGRGTQRP-LTQRHSSESSSELSSSAWPGTIWTS--TLSPGQRLPTPP 266
            PP  + T P  P  G Q P L    +    +  ++    GT+        P  R   PP
Sbjct: 675 TPP-QTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPP 733

Query: 267 PPDPAALTSWG 277
           PP P  + S G
Sbjct: 734 PPQPPGVHSAG 744


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 78/331 (23%), Positives = 113/331 (34%), Gaps = 32/331 (9%)

Query: 50  RQRPPETLQPPANRGGGPVGAPRVSRRREGL-------RALKVPGSEPQVGAEVRPSSRK 102
           R  PP T  P       P  + R  + R  +       +  K  G+E +      P  RK
Sbjct: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 459

Query: 103 -----SLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSS 157
                S  D  G        +QRR++  Q       +  +  ++ + P    +RS + + 
Sbjct: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP----KRSHVKNG 515

Query: 158 PRWFSSRHS---SISEGEGDRCGFAEPPG----GSSPPAPPLPPPPKPGSPTQRAREASS 210
                 RHS   S S     R     P G      SPP       P P  P +R R  + 
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPT- 574

Query: 211 WKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDP 270
             PP    T  P    + P  +R+S       S S  P     S   P +R  +P PP  
Sbjct: 575 --PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632

Query: 271 AALTSWGLPQQQGACVPE--GIALALRCRAMGPWEEQNWSATSGSP----GPGPHPRSRP 324
             ++    P+Q+ + V +    +L+ + R           A S  P     P P PR+  
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692

Query: 325 TPPRLPYPRRAAGTVGIGRPSRGPGGSSSRR 355
           T    P  RR A +    R S  P     RR
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTRPIRR 723



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 69/290 (23%), Positives = 99/290 (34%), Gaps = 62/290 (21%)

Query: 48  EGRQRPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDH 107
           E +++ PE  +P        V  P V         LKVP  EP +     PS  K+    
Sbjct: 215 EKKEKTPELPEPSVK-----VKEPSVQEATSTSDILKVPKPEP-IPEPKEPSPEKNSK-- 266

Query: 108 RGLGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSS 167
                 + + +++ R     P  R R+K   +T+ + P         H+ PR    RH S
Sbjct: 267 ------KEKEKEKTR-----PRSRSRSKSRSRTRSRSPS--------HTRPR---RRHRS 304

Query: 168 ISEGEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQ 227
            S     R            P+P   P P+  +P +R        PP H  +  P R  +
Sbjct: 305 RSRSYSPR----------RRPSPRRRPSPRRRTPPRRMPP-----PPRHRRSRSPVRRRR 349

Query: 228 RPLTQRHSSESSSELSSSAWP----------GTIWTSTLSPG------QRLPTPPPPDPA 271
           R       S SSS  S S  P              T  LSP       +  P+PP   P 
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPP 409

Query: 272 ALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPR 321
                  PQQ        ++++   R  G   +   +    SP P P PR
Sbjct: 410 KTRHSPTPQQSNRTRKSRVSVS-PGRTSGKVTKHKGTEKRESPSPAPKPR 458



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 36/152 (23%), Positives = 57/152 (37%), Gaps = 10/152 (6%)

Query: 193 PPPPKPGSPTQRAREASSWKPPGH--SHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGT 250
           P P +  SP +R R+ S  + P H     +P     ++  T      S      S    T
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEAT 239

Query: 251 IWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALAL---RCRAMGPWEEQ-- 305
             +  L   +  P P P +P+   +    +++    P   + +    R R+  P   +  
Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPR 299

Query: 306 ---NWSATSGSPGPGPHPRSRPTPPRLPYPRR 334
                 + S SP   P PR RP+P R   PRR
Sbjct: 300 RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRR 331



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 37/160 (23%), Positives = 54/160 (33%), Gaps = 21/160 (13%)

Query: 59  PPANRGGGPVGAPRVSRRREGLRALKVPGSEP----QVGAEVRPSSRKSLSDHRGLGRGR 114
           PP  +   PV      RR   L +    GS P    +     +P+ R S S      +  
Sbjct: 639 PPPKQRSSPV----TKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694

Query: 115 RRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHS-SPRWFSSRHSSISEGEG 173
                 RR  + +P  R    P+ +  R+       + +  + SP   S R  S S    
Sbjct: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSV- 753

Query: 174 DRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKP 213
                      S  P P    PP P SP Q    +++W P
Sbjct: 754 -----------SGSPEPAAKKPPAPPSPVQSQSPSTNWSP 782


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 67/297 (22%), Positives = 103/297 (34%), Gaps = 57/297 (19%)

Query: 75  RRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRA 134
           RR E ++AL+      Q   E +   RK L + R   R +R+ +Q   +       + + 
Sbjct: 428 RRLEDMQALRREEERRQAERE-QEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQ--QQQQ 484

Query: 135 KPALQTQRKEPLVFTQRSLLH---------SSPRWFSSRHSSISEGEGDRCGFAEPPGGS 185
           +  LQ Q+++ L+   R  L+           P W           +      A+   GS
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544

Query: 186 SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSS 245
           + P PP+P    PG             PPG     PP +    P    H S  +  +   
Sbjct: 545 TGPEPPIPQA-SPG-------------PPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLK 590

Query: 246 AWPGTIWTSTLSPGQ------RLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAM 299
            +   +  S     Q        P    PDPA       P  +GA +             
Sbjct: 591 PYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVI------------- 637

Query: 300 GPWEEQNWSATSGSPGPGPHPRS--RP---TPPRLPYPRRAAGTVGIGRPSRGPGGS 351
                QN   TS  PGP P+P +  RP    PP++P   +   ++     + G GGS
Sbjct: 638 ----RQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVP---QRTSSIATALNTSGAGGS 687


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 67/297 (22%), Positives = 103/297 (34%), Gaps = 57/297 (19%)

Query: 75  RRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRA 134
           RR E ++AL+      Q   E +   RK L + R   R +R+ +Q   +       + + 
Sbjct: 428 RRLEDMQALRREEERRQAERE-QEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQ--QQQQ 484

Query: 135 KPALQTQRKEPLVFTQRSLLH---------SSPRWFSSRHSSISEGEGDRCGFAEPPGGS 185
           +  LQ Q+++ L+   R  L+           P W           +      A+   GS
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544

Query: 186 SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSS 245
           + P PP+P    PG             PPG     PP +    P    H S  +  +   
Sbjct: 545 TGPEPPIPQA-SPG-------------PPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLK 590

Query: 246 AWPGTIWTSTLSPGQ------RLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAM 299
            +   +  S     Q        P    PDPA       P  +GA +             
Sbjct: 591 PYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVI------------- 637

Query: 300 GPWEEQNWSATSGSPGPGPHPRS--RP---TPPRLPYPRRAAGTVGIGRPSRGPGGS 351
                QN   TS  PGP P+P +  RP    PP++P   +   ++     + G GGS
Sbjct: 638 ----RQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVP---QRTSSIATALNTSGAGGS 687


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 67/297 (22%), Positives = 103/297 (34%), Gaps = 57/297 (19%)

Query: 75  RRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRA 134
           RR E ++AL+      Q   E +   RK L + R   R +R+ +Q   +       + + 
Sbjct: 428 RRLEDMQALRREEERRQAERE-QEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQ--QQQQ 484

Query: 135 KPALQTQRKEPLVFTQRSLLH---------SSPRWFSSRHSSISEGEGDRCGFAEPPGGS 185
           +  LQ Q+++ L+   R  L+           P W           +      A+   GS
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544

Query: 186 SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSS 245
           + P PP+P    PG             PPG     PP +    P    H S  +  +   
Sbjct: 545 TGPEPPIPQA-SPG-------------PPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLK 590

Query: 246 AWPGTIWTSTLSPGQ------RLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAM 299
            +   +  S     Q        P    PDPA       P  +GA +             
Sbjct: 591 PYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVI------------- 637

Query: 300 GPWEEQNWSATSGSPGPGPHPRS--RP---TPPRLPYPRRAAGTVGIGRPSRGPGGS 351
                QN   TS  PGP P+P +  RP    PP++P   +   ++     + G GGS
Sbjct: 638 ----RQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVP---QRTSSIATALNTSGAGGS 687


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 38/199 (19%)

Query: 176 CGFAEPPGGSSPPAPPL--------PPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQ 227
           C F +P  GS+P              PPP PGS    +     ++  G S   PP R   
Sbjct: 257 CSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGT 316

Query: 228 RPLTQRHSSESSSELSSSAWPGT--IWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGAC 285
            P  Q+ ++ SS        PGT   WT+ L     LP   P D  A        + G  
Sbjct: 317 PP--QQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPA----SKRPRPGGV 370

Query: 286 VPEG---------IALALRCRAMGPWEEQNWSATSG-----------SPGPGPHPRSRPT 325
            PE          +  +      GP + +   A  G           +PG G  P  RP 
Sbjct: 371 SPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSP--RPA 428

Query: 326 PPRLPYPRRAAGTVGIGRP 344
           PPRL  P R+    G+ +P
Sbjct: 429 PPRLGKPPRSRPPQGLAQP 447



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 11/129 (8%)

Query: 203 QRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLSPGQRL 262
           + AR    W PP  S T      T  PL +      + + S     G++W          
Sbjct: 169 KEARGTQGWWPP-QSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTR----- 222

Query: 263 PTPPPPDPA-ALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPR 321
           P PP P PA  LT  G  + +GA    G+    R R     +    SA S S   G   R
Sbjct: 223 PPPPRPSPAPGLTGRGQGRARGAV---GLDCGCRPRPCSFGQPDVGSAPSRSL-RGCSLR 278

Query: 322 SRPTPPRLP 330
            R TPP +P
Sbjct: 279 FRNTPPPIP 287


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 42/153 (27%), Positives = 59/153 (38%), Gaps = 25/153 (16%)

Query: 187 PPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSSA 246
           PP+ P PPPP P SP    +  +S    G  +     RGT   ++ R             
Sbjct: 786 PPSQPQPPPPPPPSPASLLKSLAS-VLEGQKYCY---RGTGAAVSTR------------- 828

Query: 247 WPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQN 306
            PG + T+  SPG     PP    A   +   P  QG+  P   + +    + GPW  + 
Sbjct: 829 -PGPLPTTQYSPG-----PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARER 882

Query: 307 WSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTV 339
                  P PGP   ++P PP    P R+   V
Sbjct: 883 --RAGEEPVPGPMTPTQPPPPLSLPPARSESEV 913



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 60/217 (27%), Positives = 77/217 (35%), Gaps = 59/217 (27%)

Query: 181 PPGGSSPPAPPLP----PPPKP----GSPTQRAREASS------WKPPGHSHTAPP---- 222
           PPG SSPP PP P    PPP P    G   + ARE         +   G    APP    
Sbjct: 462 PPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH 521

Query: 223 ------------GRGTQ---------RPLTQRHSSESSSELSSSAWPGTI-----WTSTL 256
                         GTQ          P T   +S S S  SS A P +         ++
Sbjct: 522 REGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSI 581

Query: 257 SPGQRLPTP---PPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSAT-SG 312
            P  R P+P   P   P    +  LP    +   +  + + R R   P    ++  T   
Sbjct: 582 DPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFR-RPESPRPRVSFPKTPEV 640

Query: 313 SPGPGPHPRSRPTPPRLPYPRRAAGTVGIGR-PSRGP 348
            PGP P P S+   P  P         G+G  P+RGP
Sbjct: 641 GPGPPPGPLSKAPQPVPP---------GVGELPARGP 668



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 75/286 (26%), Positives = 99/286 (34%), Gaps = 51/286 (17%)

Query: 88  SEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPL- 146
           +EP V   V P++    S   GL  G +RRR      T  P G     P L      P  
Sbjct: 201 AEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP 260

Query: 147 -------VFTQRSLLHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLP-PPPKP 198
                  + T      + P  +S+ H      E  R G A P       + P P P P P
Sbjct: 261 PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPE--RKGSAPPERQEQRHSLPHPYPYPAP 318

Query: 199 GSPTQRAREASSWKPPGHS--HTAPPGRGTQRPLTQRH-----SSESSSELSSSAWPGTI 251
                    A +  PPGH     APPG G + P  + H     +    S+L  S    + 
Sbjct: 319 ---------AYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSR 369

Query: 252 WTSTLSPGQR------LPTPPPPDPAALTS--------WGL------PQQQGACVPEGIA 291
             S++SP          P+ PP  P   TS         GL      P   GA   +  A
Sbjct: 370 MDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPA 429

Query: 292 LALRCRA-MGPWEEQNWSATSGSPGPGPH---PRSRPTPPRLPYPR 333
           L +     +GP    +     G+P   PH   P    +PP  P PR
Sbjct: 430 LEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPR 475



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 51/195 (26%), Positives = 64/195 (32%), Gaps = 37/195 (18%)

Query: 188 PAPPLPPPPKPGSPTQRAREASS------WKP----PGHSHTAPPGRGTQRPLTQRHSSE 237
           P  P  PP  PG+ T  +  +SS       +P    PG  H   P            S+ 
Sbjct: 384 PYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH 443

Query: 238 SSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCR 297
           SS +    A P      +L PG   P PPPP P  L     P    A +      A   R
Sbjct: 444 SSRKPFLGA-PAATPHLSLPPGPSSP-PPPPCPRLLR----PPPPPAWLKGPACRA--AR 495

Query: 298 AMGPWEEQNWSATSGSPGPGPHP-------------------RSRPTPPRLPYPRRAAGT 338
             G   E+ +  T G P P P P                   +   TPP  P P  ++  
Sbjct: 496 EDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSN 555

Query: 339 VGIGRPSRGPGGSSS 353
              G  S  P G  S
Sbjct: 556 SNSGSHSSSPAGPVS 570



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 48/173 (27%), Positives = 57/173 (32%), Gaps = 41/173 (23%)

Query: 181 PPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPL-TQRHSSESS 239
           PPG   PP PPLPPPP P  P            PG + T+PP + T+  L +  H     
Sbjct: 241 PPGLPLPP-PPLPPPPPPPPPPPPPL-------PGLA-TSPPFQLTKPGLWSTLHGDAWG 291

Query: 240 SELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAM 299
            E   SA P             LP P P    A T+           P G  L       
Sbjct: 292 PERKGSAPP-----ERQEQRHSLPHPYPYPAPAYTAH----------PPGHRLV------ 330

Query: 300 GPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSS 352
                      +  PGPGP P    +   LP  R     +   R  R    SS
Sbjct: 331 ----------PAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 12/128 (9%)

Query: 94   AEVRPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSL 153
            A V  S ++   +H+   R R RR  +   G +   GR +AK  +  ++   ++      
Sbjct: 966  AAVSGSCKRRQKEHQKEHR-RHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN---- 1020

Query: 154  LHSSPRWFSSRHSSISEGEGDRCGFAEPPGGSSPPAPPLPP----PPKPGSPTQRAREAS 209
            L         R  S  +  G     A+PP   +PP+ P P     PP    P ++ARE +
Sbjct: 1021 LDLQSEEIQGREKSRPDLGG--ASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEA 1078

Query: 210  SWKPPGHS 217
               PPG S
Sbjct: 1079 P-GPPGVS 1085


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 48/170 (28%), Positives = 60/170 (35%), Gaps = 15/170 (8%)

Query: 181 PPGGSSPPAPPLPPPPKP-GSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESS 239
           P GG+ P  PP PPP KP G P Q   +     PPG     PP    Q   ++   S   
Sbjct: 41  PQGGNKPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP----QGDKSRSPRSPPG 95

Query: 240 SELSSSAWPGTIWTSTLSPGQRLPTPPPP-DPAALTSWGLPQQQGACVPEGIALALRCRA 298
                    G         G +   PPPP  P    + G  + Q A  P G       + 
Sbjct: 96  KPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG-------KP 148

Query: 299 MGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGP 348
            GP  +Q  +   G P P      +P  P    P+        GRPSR P
Sbjct: 149 QGP-PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 13/43 (30%), Positives = 19/43 (44%)

Query: 172 EGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPP 214
           EG+      PP G +P  P  PP  +P  P +  +     +PP
Sbjct: 155 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 67/242 (27%), Positives = 92/242 (38%), Gaps = 53/242 (21%)

Query: 126 QAPCG----RLRAKPALQTQRKEPLVFTQR-SLLHSSPRWF---SSRHSSISEGEGDRCG 177
           Q PCG    +L A    +    +P+V  Q  S+    P      S       EGEG+   
Sbjct: 656 QHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKL 715

Query: 178 FAEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSE 237
             E   GS     P  P P PG       + ++ +P G S      +G  RP     +  
Sbjct: 716 SLEAHAGSPSLKTPDGPVPGPGP------QGAAPEPLGASVQRDSAQG--RPCPPPQAPA 767

Query: 238 SSSELSSSAWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGAC--VPEGIAL-AL 294
           +  E +SSA PG+            P P PP  A+     LP +QG    +P G+A   L
Sbjct: 768 NQPEGASSAAPGS------------PVPAPPTKAS----ALPVEQGPAEPIPPGVASGGL 811

Query: 295 RCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPGGSSSR 354
           R  A+GP        T+   GP  HP         P P R+  T   G+   GPG + + 
Sbjct: 812 RPDALGP--------TTAHHGP-RHP---------PKPPRSKATERPGQEPEGPGATPAG 853

Query: 355 RR 356
            R
Sbjct: 854 ER 855



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 42/171 (24%), Positives = 59/171 (34%), Gaps = 21/171 (12%)

Query: 171 GEGDRCGFAEPPGGS----SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGT 226
           G G +    EP G S    S    P PPP  P +  + A  A+    PG    APP + +
Sbjct: 735 GPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAA----PGSPVPAPPTKAS 790

Query: 227 QRPLTQRHSSESSSELSSSAW-PGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGAC 285
             P+ Q  +      ++S    P  +  +T   G R P  PP   A       P+  GA 
Sbjct: 791 ALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGA- 849

Query: 286 VPEGIALALRCRAMGPWEEQNWSATSGSPGPGPHPRSRPTPPRLPYPRRAA 336
                         G  ++Q+  +    P P       P     P P R A
Sbjct: 850 -----------TPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTA 889


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 66/291 (22%), Positives = 99/291 (34%), Gaps = 65/291 (22%)

Query: 75  RRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRGLGRGRRRRRQRRRWGTQAPCGRLRA 134
           RR E ++AL+      Q   E +   RK L + R   R +R+ +Q   +       + + 
Sbjct: 428 RRLEDMQALRREEERRQAERE-QEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQ--QQQQ 484

Query: 135 KPALQTQRKEPLVFTQRSLLH---------SSPRWFSSRHSSISEGEGDRCGFAEPPGGS 185
           +  LQ Q+++ L+   R  L+           P W           +      A+   GS
Sbjct: 485 QQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGS 544

Query: 186 SPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSESSSELSSS 245
           + P PP+P    PG             PPG     PP +    P    H S       + 
Sbjct: 545 TGPEPPIPQA-SPG-------------PPGPLSQTPPMQRPVEPQEGPHKSLQDQPTRNL 590

Query: 246 AWPGTIWTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQ 305
           A                P    PDPA       P  +GA +                  Q
Sbjct: 591 A--------------AFPASHDPDPAIPAPTATPSARGAVI-----------------RQ 619

Query: 306 NWSATSGSPGPGPHPRS--RP---TPPRLPYPRRAAGTVGIGRPSRGPGGS 351
           N   TS  PGP P+P +  RP    PP++P   +   ++     + G GGS
Sbjct: 620 NSDPTSEGPGPSPNPPAWVRPDNEAPPKVP---QRTSSIATALNTSGAGGS 667


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 54/180 (30%), Positives = 63/180 (35%), Gaps = 14/180 (7%)

Query: 179 AEPPGGSSPPAPPLPPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQRHSSES 238
           A PP    PP    PP P PG   Q         P G  H +  G     PL QR  S +
Sbjct: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512

Query: 239 SS--ELSSSAWPGTIWTSTLS------PGQRLPTPPPPDPAALTSWGLPQQQGACVPEGI 290
           S+  + +S A P T      S      PG      PP  P+     G PQ        G 
Sbjct: 513 SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP 572

Query: 291 ALALRCRAMGPWEEQNWSATSGSPGP-GPHPRSRPTPPRLPYPRRAAGTVGIGRPSRGPG 349
           A   +     P  +Q        PGP GP   +R      P PR    T    RPS GPG
Sbjct: 573 A-PPKASGAPPGGQQRQGPPQKPPGPAGP---TRQASQAGPVPRTGPPTTQQPRPS-GPG 627



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 61/221 (27%), Positives = 81/221 (36%), Gaps = 40/221 (18%)

Query: 50  RQRPPETLQPPANRGGGPVGAPRVSRRREGLRALKVPGSEPQVGAEVRPSSRKSLSDHRG 109
           +QRPP   Q   +  G P G+P   R       L  P S PQ     +P+S+ +      
Sbjct: 482 QQRPPPQGQQHLSGLGPPAGSPLPQR-------LPSPTSAPQ-----QPASQAAPPTQ-- 527

Query: 110 LGRGRRRRRQRRRWGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSIS 169
            G+GR+ R      G   P  R  A P+ Q Q   P    Q S+   +P   S       
Sbjct: 528 -GQGRQSRPVAGGPGA-PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKAS------- 578

Query: 170 EGEGDRCGFAEPPGGSSPPAPPLPPPPKPGSPTQRAREAS---SWKPPGHSHTAPPGRG- 225
                      PPGG     PP   PP P  PT++A +A       PP      P G G 
Sbjct: 579 ---------GAPPGGQQRQGPP-QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGP 628

Query: 226 TQRP---LTQRHSSESSSELSSSAWPGTIWTSTLSPGQRLP 263
             RP   L Q+ S +     +++A          SP Q  P
Sbjct: 629 AGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669


>gi|239755304 PREDICTED: hypothetical protein XP_002344521 [Homo
           sapiens]
          Length = 209

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 47/173 (27%), Positives = 65/173 (37%), Gaps = 16/173 (9%)

Query: 193 PPPPKPGSPTQRAREASSWKPPGHSHTAPPGRGTQRPLTQ-RHSSESSSELSSSAWPGTI 251
           PPPP PG  ++    AS+ +PPG +  A P  G    + + R       E         I
Sbjct: 36  PPPPSPGRGSELG--ASAQRPPGPAFLAAPAFGAGLAVGRLRRVGRRGPEKRQPGRKPPI 93

Query: 252 WTSTLSPGQRLPTPPPPDPAALTSWGLPQQQGACVPEGIALALRCRAMGPWEEQNWSATS 311
                    RL +P PP   +   W L      C+ EG  +  R   + P    +W+   
Sbjct: 94  DPLGGPALPRLSSPEPPPAGSDRDWRLR----LCLREGEGVLWRRFPLTPPPSGSWACRV 149

Query: 312 GSPGPG-------PHPRSRPTPPRLPYPRRAAGTVGI--GRPSRGPGGSSSRR 355
            + G G       P  R  P PP LPYP   A         P+R    +S+RR
Sbjct: 150 SAMGEGCARCLRLPPRRGPPRPPGLPYPGGLAAPRASPPQHPNRAAPPASARR 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,199,465
Number of Sequences: 37866
Number of extensions: 1631821
Number of successful extensions: 30665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 540
Number of HSP's successfully gapped in prelim test: 1532
Number of HSP's that attempted gapping in prelim test: 14243
Number of HSP's gapped (non-prelim): 11201
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.