Guide to the Human Genome
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Search of human proteins with 119120915

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119120915 rhophilin 1 [Homo sapiens]
         (670 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119120915 rhophilin 1 [Homo sapiens]                              1347   0.0  
gi|228008333 rhophilin, Rho GTPase binding protein 2 [Homo sapiens]   484   e-137
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...   134   4e-31
gi|241982780 programmed cell death 6 interacting protein isoform...    96   8e-20
gi|22027538 programmed cell death 6 interacting protein isoform ...    96   8e-20
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int...    57   7e-08
gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isof...    55   2e-07
gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isofo...    55   2e-07
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo...    53   8e-07
gi|71897229 solute carrier family 9 isoform 3 regulator 2 isofor...    53   8e-07
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    52   1e-06
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo...    52   1e-06
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    52   2e-06
gi|62865654 regulator of G-protein signalling 3 isoform 3 [Homo ...    52   2e-06
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]     51   4e-06
gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo sapi...    49   2e-05
gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ...    49   2e-05
gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo...    49   2e-05
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s...    47   4e-05
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]     47   7e-05
gi|8922944 lin-7 homolog C [Homo sapiens]                              44   4e-04
gi|11545920 lin-7 homolog B [Homo sapiens]                             44   4e-04
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi...    44   5e-04
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]             44   5e-04
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              44   5e-04
gi|112382257 InaD-like [Homo sapiens]                                  44   5e-04
gi|4759306 lin-7 homolog A [Homo sapiens]                              44   5e-04
gi|21361142 PDZ domain containing 1 [Homo sapiens]                     43   8e-04
gi|193083191 synaptopodin 2 isoform c [Homo sapiens]                   43   8e-04
gi|193083185 synaptopodin 2 isoform b [Homo sapiens]                   43   8e-04

>gi|119120915 rhophilin 1 [Homo sapiens]
          Length = 670

 Score = 1347 bits (3486), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 1   MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRA 60
           MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRA
Sbjct: 1   MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRA 60

Query: 61  TSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKEL 120
           TSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKEL
Sbjct: 61  TSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKEL 120

Query: 121 DWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDA 180
           DWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDA
Sbjct: 121 DWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDA 180

Query: 181 RFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGAR 240
           RFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGAR
Sbjct: 181 RFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGAR 240

Query: 241 RAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAP 300
           RAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAP
Sbjct: 241 RAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAP 300

Query: 301 QDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVA 360
           QDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVA
Sbjct: 301 QDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVA 360

Query: 361 MALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEA 420
           MALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEA
Sbjct: 361 MALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEA 420

Query: 421 LRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEAR 480
           LRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEAR
Sbjct: 421 LRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEAR 480

Query: 481 MPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIP 540
           MPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIP
Sbjct: 481 MPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIP 540

Query: 541 GSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLG 600
           GSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLG
Sbjct: 541 GSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLG 600

Query: 601 DRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAP 660
           DRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAP
Sbjct: 601 DRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAP 660

Query: 661 PSSLKHPGWP 670
           PSSLKHPGWP
Sbjct: 661 PSSLKHPGWP 670


>gi|228008333 rhophilin, Rho GTPase binding protein 2 [Homo sapiens]
          Length = 686

 Score =  484 bits (1247), Expect = e-137
 Identities = 265/578 (45%), Positives = 370/578 (64%), Gaps = 6/578 (1%)

Query: 20  QGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNS 79
           +GC+ L Q    +LQ++RA ++QQI K ++MRTGAENL +  +N++VRE V LELS+VNS
Sbjct: 23  KGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNSKVREQVRLELSFVNS 82

Query: 80  NLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGA 139
           +LQ+LKEELE L+  V   ++  EA T+P+IPLGLKETK++D++  LK+ I  H+ EDG 
Sbjct: 83  DLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKETKDVDFAVVLKDFILEHYSEDGY 142

Query: 140 SYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSL 199
            YE EI +L  LRQA RTPSR+E+G+ELL  Y+ QL F+++RF  P R +GL F WYDSL
Sbjct: 143 LYEDEIADLMDLRQACRTPSRDEAGVELLMTYFIQLGFVESRFFPPTRQMGLLFTWYDSL 202

Query: 200 TGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLREN 259
           TGVP  Q+ L  EK SVLFN GAL+TQIG R DR    G   A++AFQRAAG  + L++ 
Sbjct: 203 TGVPVSQQNLLLEKASVLFNTGALYTQIGTRCDRQTQAGLESAIDAFQRAAGVLNYLKDT 262

Query: 260 FSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAE 319
           F+H PS DMS A L  L ++M+AQAQE VFE +S P      +    +++AQEAA+V   
Sbjct: 263 FTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKISLPG--IRNEFFMLVKVAQEAAKVGEV 320

Query: 320 YRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQ 379
           Y+ +H  M+Q PV + +P SW +L  VKA ++ +LAHY  A+ L D       +L  H++
Sbjct: 321 YQQLHAAMSQAPVKENIPYSWASLACVKAHHYAALAHYFTAILLIDHQVKPGTDL-DHQE 379

Query: 380 VFLQPPTSSKPRGPVLPQEL---EERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLL 436
             L       P G      L   ++RRQLGK+HL+RA+   EE++R  +LC+ LR +++L
Sbjct: 380 KCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLRRAMAHHEESVREASLCKKLRSIEVL 439

Query: 437 RAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRL 496
           + V+    +RS   YA+   EDD     +AP +  KT Q+ +  +P+ S+    D F +L
Sbjct: 440 QKVLCAAQERSRLTYAQHQEEDDLLNLIDAPSVVAKTEQEVDIILPQFSKLTVTDFFQKL 499

Query: 497 GPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIV 556
           GPLSVFSA  RW     +  T  EG  G TLRG++PV +  + P   A+ AG +EGDYIV
Sbjct: 500 GPLSVFSANKRWTPPRSIRFTAEEGDLGFTLRGNAPVQVHFLDPYCSASVAGAREGDYIV 559

Query: 557 SVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSS 594
           S+    C+W   +EV+  LK+ GE    ++VVSLL S+
Sbjct: 560 SIQLVDCKWLTLSEVMKLLKSFGEDEIEMKVVSLLDST 597


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23
           [Homo sapiens]
          Length = 1636

 Score =  134 bits (336), Expect = 4e-31
 Identities = 115/413 (27%), Positives = 187/413 (45%), Gaps = 62/413 (15%)

Query: 107 VPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQ-AMRTPSRNESGL 165
           +PMI L LKE  +  +   +K+ +  ++GE+  +Y  E+++LE LRQ A+R P R+  G 
Sbjct: 7   MPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVP-RDFEGC 65

Query: 166 ELLTAYYNQLCFLDARF-LTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALH 224
            +L  Y  QL +L +R  +   +   +   W +  +G       + +E+  +L+N+GALH
Sbjct: 66  SVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALH 125

Query: 225 TQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQA 284
           + +GA   R   EG + +   FQ AAGAF+ LRE+F  A S DMS   L     LM+ QA
Sbjct: 126 SMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQA 185

Query: 285 QECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDY---VPVSWT 341
           QEC+ E        +  D      +A+ +AQV   Y+   R +  P        +   W 
Sbjct: 186 QECLLE-------KSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWK 238

Query: 342 ALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEE 401
            LV +K  YF ++AH H+                                     ++ EE
Sbjct: 239 KLVQMKIYYFAAVAHLHMG------------------------------------KQAEE 262

Query: 402 RRQLGK--AHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDD 459
           +++ G+  A+ + A+    EA++L        + D ++  +  T+     KY    +++D
Sbjct: 263 QQKFGERVAYFQSALDKLNEAIKL-----AKGQPDTVQDALRFTMDVIGGKYNSAKKDND 317

Query: 460 FC--EAAEAPD-IQPKTHQ---KPEARMPRLSQGKGPDIFHRLGPLSVFSAKN 506
           F   EA  A D +QP       KP    P      GPDIF +L P++   A +
Sbjct: 318 FIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASS 370


>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 70/196 (35%), Positives = 102/196 (52%), Gaps = 16/196 (8%)

Query: 110 IPLGLKETKELDWSTPLKELISVHF---GEDGASYEAEIRELEALRQAM--RTPSRNESG 164
           I + LK+T E+D + PL + I   +   GE+ A Y     EL  LR+A   R   ++E  
Sbjct: 5   ISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGA 64

Query: 165 LELLTAYYNQLCFLDARFLTPARSLGLFFHWYD-----SLTG--VPAQQRALAFEKGSVL 217
           LE L  YY+Q+C ++ +F      + L F W D     SL G  V     +L +EK  VL
Sbjct: 65  LETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVL 124

Query: 218 FNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLREN----FSHAPSPDMSAASL 273
           FN  AL +QI A Q+    EG + A + +Q A+GAF  ++E      S  P+ D+S  ++
Sbjct: 125 FNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTV 184

Query: 274 CALEQLMMAQAQECVF 289
             L  +M+AQAQE  F
Sbjct: 185 GTLSLIMLAQAQEVFF 200


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 70/196 (35%), Positives = 102/196 (52%), Gaps = 16/196 (8%)

Query: 110 IPLGLKETKELDWSTPLKELISVHF---GEDGASYEAEIRELEALRQAM--RTPSRNESG 164
           I + LK+T E+D + PL + I   +   GE+ A Y     EL  LR+A   R   ++E  
Sbjct: 5   ISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGA 64

Query: 165 LELLTAYYNQLCFLDARFLTPARSLGLFFHWYD-----SLTG--VPAQQRALAFEKGSVL 217
           LE L  YY+Q+C ++ +F      + L F W D     SL G  V     +L +EK  VL
Sbjct: 65  LETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVL 124

Query: 218 FNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLREN----FSHAPSPDMSAASL 273
           FN  AL +QI A Q+    EG + A + +Q A+GAF  ++E      S  P+ D+S  ++
Sbjct: 125 FNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTV 184

Query: 274 CALEQLMMAQAQECVF 289
             L  +M+AQAQE  F
Sbjct: 185 GTLSLIMLAQAQEVFF 200


>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
           interacting protein [Homo sapiens]
          Length = 1211

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 32/79 (40%), Positives = 44/79 (55%)

Query: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
           V + +G   FG TLRG  PV I +V+PGS A  A LK GD I+ +NG   R   H +VV+
Sbjct: 280 VRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNAALKSGDRILFLNGLDMRNCSHDKVVS 339

Query: 574 ELKAAGEAGASLQVVSLLP 592
            L+ +G     +    L+P
Sbjct: 340 MLQGSGAMPTLVVEEGLVP 358



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 2/90 (2%)

Query: 523 FGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAG 582
           FG  L G  P  +  V  GS A A GL+ GD I+ V G          +V   +      
Sbjct: 17  FGFRLGGSGPCFVLEVAKGSSAHAGGLRPGDQILEVEGLAVGGLSRERLVRLARRCPRVP 76

Query: 583 ASLQVVSLLPSSRLPSLGDRRP--VLLGPR 610
            SL V+        P  G   P  VL  PR
Sbjct: 77  PSLGVLPAPDGGPGPGSGPAAPTTVLRAPR 106


>gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isoform
           2 [Homo sapiens]
          Length = 1562

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 14/120 (11%)

Query: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
           V + + + GFG T+ GD  VL+ +V PG  A  AG+KEGD I+ VNG       H EVV 
Sbjct: 48  VIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVK 107

Query: 574 ELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRP 633
            +K+   A  +L ++   PSS            +G  GL +     G     S   SP P
Sbjct: 108 LIKSG--AYVALTLLGSSPSS------------MGISGLQQDPSPAGAPRITSVIPSPPP 153


>gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isoform
           1 [Homo sapiens]
          Length = 1522

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 14/120 (11%)

Query: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
           V + + + GFG T+ GD  VL+ +V PG  A  AG+KEGD I+ VNG       H EVV 
Sbjct: 48  VIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVK 107

Query: 574 ELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRP 633
            +K+   A  +L ++   PSS            +G  GL +     G     S   SP P
Sbjct: 108 LIKSG--AYVALTLLGSSPSS------------MGISGLQQDPSPAGAPRITSVIPSPPP 153


>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
           a [Homo sapiens]
          Length = 337

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 31/76 (40%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 515 HLTRGEGGFGLTLRGDSP---VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEV 571
           HL +G  G+G  L  D       I +V PGS AA +GL+  D ++ VNGQ     RHAEV
Sbjct: 153 HLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEV 212

Query: 572 VTELKAAGEAGASLQV 587
           V  +KA  +    L V
Sbjct: 213 VASIKAREDEARLLVV 228



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 28/65 (43%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 516 LTRGEGGFGLTLRGDSP---VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVV 572
           L RGE G+G  L G+       I  V PGS A AA L+ GD +V VNG       H +VV
Sbjct: 14  LVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVV 73

Query: 573 TELKA 577
             +KA
Sbjct: 74  QRIKA 78


>gi|71897229 solute carrier family 9 isoform 3 regulator 2 isoform b
           [Homo sapiens]
          Length = 326

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 31/76 (40%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 515 HLTRGEGGFGLTLRGDSP---VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEV 571
           HL +G  G+G  L  D       I +V PGS AA +GL+  D ++ VNGQ     RHAEV
Sbjct: 153 HLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEV 212

Query: 572 VTELKAAGEAGASLQV 587
           V  +KA  +    L V
Sbjct: 213 VASIKAREDEARLLVV 228



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 28/65 (43%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 516 LTRGEGGFGLTLRGDSP---VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVV 572
           L RGE G+G  L G+       I  V PGS A AA L+ GD +V VNG       H +VV
Sbjct: 14  LVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVV 73

Query: 573 TELKA 577
             +KA
Sbjct: 74  QRIKA 78


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 43/172 (25%), Positives = 72/172 (41%), Gaps = 21/172 (12%)

Query: 494 HRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGD 553
           +R   L    ++ R+R    + + RG+ GFG T+  DSPV + AV  G  A  AGL++ D
Sbjct: 2   NRFNGLCKVCSERRYR---QITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLD 58

Query: 554 YIVSVNGQPCRWWRHAEVVTELKAA-----------------GEAGASLQVVSLLPSSRL 596
            ++ +N +P   W+  E+  E+++                  G  G  L+  S   +  L
Sbjct: 59  TVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDL 118

Query: 597 PSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGG 648
            S  ++R          R ++ H C     + +    L  W R  +  K GG
Sbjct: 119 QSPPNKREKNCTHGVQARPEQRHSCHLVCDS-SDGLLLGGWERYTEVAKRGG 169


>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
           sapiens]
          Length = 1544

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 8/104 (7%)

Query: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
           V + + + GFGLT+ GD+PV + +V     A  AG++ GD I+ VNG       H EVV 
Sbjct: 73  VIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVK 132

Query: 574 ELKAAGEAGASLQ-------VVSLLPSSRLPS-LGDRRPVLLGP 609
            +K+      ++Q        + L  S   PS +G   P++  P
Sbjct: 133 LIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSP 176


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
           sapiens]
          Length = 1198

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 18/152 (11%)

Query: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
           + + RG+ GFG T+  DSPV + AV  G  A  AGL++ D ++ +N +P   W+  E+  
Sbjct: 300 ITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAH 359

Query: 574 ELKAA-----------------GEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQ 616
           E+++                  G  G  L+  S   +  L S  ++R          R +
Sbjct: 360 EIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPE 419

Query: 617 REHGCKTPASTWASPRPLLNWSRKAQQGKTGG 648
           + H C     + +    L  W R  +  K GG
Sbjct: 420 QRHSCHLVCDS-SDGLLLGGWERYTEVAKRGG 450


>gi|62865654 regulator of G-protein signalling 3 isoform 3 [Homo
           sapiens]
          Length = 602

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 18/152 (11%)

Query: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
           + + RG+ GFG T+  DSPV + AV  G  A  AGL++ D ++ +N +P   W+  E+  
Sbjct: 188 ITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAH 247

Query: 574 ELKAA-----------------GEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQ 616
           E+++                  G  G  L+  S   +  L S  ++R          R +
Sbjct: 248 EIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPE 307

Query: 617 REHGCKTPASTWASPRPLLNWSRKAQQGKTGG 648
           + H C     + +    L  W R  +  K GG
Sbjct: 308 QRHSCHLVCDS-SDGLLLGGWERYTEVAKRGG 338


>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
          Length = 262

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 43/146 (29%), Positives = 66/146 (45%), Gaps = 12/146 (8%)

Query: 514 VHLTRGEGGFGLTL------RGDSPVLIAAVIPGSQAAAAG-LKEGDYIVSVNGQPCRWW 566
           V L RG  GFGLTL       GD+P+ +  ++    A   G L+ GD ++ +NG+  +  
Sbjct: 59  VELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGL 118

Query: 567 RHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPAS 626
            HA+ V  ++A    G  L +V   P    P  G  R V    +G+ RS    G +   S
Sbjct: 119 THAQAVERIRA---GGPQLHLVIRRPLETHP--GKPRGVGEPRKGVDRSPDPGGPEVTGS 173

Query: 627 TWASPRPLLNWSRKAQQGKTGGCPQP 652
             +S   + +   +    KT G P+P
Sbjct: 174 RSSSTSLVQHPPSRTTLKKTRGSPEP 199


>gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo
           sapiens]
          Length = 907

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 5/87 (5%)

Query: 514 VHLTRGEG-GFGLTLRGDSP----VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRH 568
           V+L  G+G   GLT+RG +     + I  V PGS+A  +GLK GD I+ VNG+      H
Sbjct: 280 VNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNILH 339

Query: 569 AEVVTELKAAGEAGASLQVVSLLPSSR 595
            E V  LK++     +++ V  LP +R
Sbjct: 340 DEAVRLLKSSRHLILTVKDVGRLPHAR 366



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 9/80 (11%)

Query: 522 GFGLTLRGDSP----VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKA 577
           G G ++RG S     + ++ V PGS A   GL+ GD I+ VN +      HAE V  LK 
Sbjct: 151 GLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALK- 209

Query: 578 AGEAGASLQVVSLLPSSRLP 597
               G+   V+S+  + R+P
Sbjct: 210 ----GSKKLVLSVYSAGRIP 225


>gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo
           sapiens]
          Length = 1376

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 511 VGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAE 570
           V  V + RG  G+G TL G +P +++ V+ GS A   GL+ GD I++VN    +   H +
Sbjct: 20  VRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRAGDQILAVNEINVKKASHED 79

Query: 571 VVTELKAAGEAGASLQVV 588
           VV   K  G+    L +V
Sbjct: 80  VV---KLIGKCSGVLHMV 94


>gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo
           sapiens]
          Length = 1447

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 511 VGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAE 570
           V  V + RG  G+G TL G +P +++ V+ GS A   GL+ GD I++VN    +   H +
Sbjct: 20  VRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRAGDQILAVNEINVKKASHED 79

Query: 571 VVTELKAAGEAGASLQVV 588
           VV   K  G+    L +V
Sbjct: 80  VV---KLIGKCSGVLHMV 94


>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
           sapiens]
          Length = 358

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 516 LTRGEGGFGLTLRGDSPVL---IAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVV 572
           L +G  G+G  L G+   L   I  V PGS A  AGL  GD +V VNG+      H +VV
Sbjct: 17  LEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVV 76

Query: 573 TELKAAGEAGASLQVVSLLPSSRLPSLG 600
           + ++AA  A   L VV      +L  LG
Sbjct: 77  SRIRAALNA-VRLLVVDPETDEQLQKLG 103



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 516 LTRGEGGFGLTLRGDSPV---LIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVV 572
           + +G  G+G  L  D       I +V P S A A+GL+  D IV VNG      +H +VV
Sbjct: 157 MKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVV 216

Query: 573 TELKAAGE 580
           + ++A G+
Sbjct: 217 SAIRAGGD 224


>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
          Length = 334

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 15/150 (10%)

Query: 514 VHLTRGEGGFGLTL------RGDSPVLIAAVIPGSQAAAAG-LKEGDYIVSVNGQPCRWW 566
           V L RG  GFGLTL       GD+P+ +  ++    A   G L+ GD ++ +NG+  +  
Sbjct: 126 VELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGL 185

Query: 567 RHAEVVTELKAAGEAGASLQVVSLLPSSRLP----SLGDRRPVLLGPRGLLRSQREHGCK 622
            HA+ V  ++A    G  L +V   P    P     +G+ R  ++ P    RS    G +
Sbjct: 186 THAQAVERIRA---GGPQLHLVIRRPLETHPGKPRGVGEPRKGVV-PSWPDRSPDPGGPE 241

Query: 623 TPASTWASPRPLLNWSRKAQQGKTGGCPQP 652
              S  +S   + +   +    KT G P+P
Sbjct: 242 VTGSRSSSTSLVQHPPSRTTLKKTRGSPEP 271


>gi|8922944 lin-7 homolog C [Homo sapiens]
          Length = 197

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 514 VHLTRGEGGFGLTLRG----DSPVLIAAVIPGSQAAA-AGLKEGDYIVSVNGQPCRWWRH 568
           V L + E G G  + G    +SP+ I+ +IPG  A    GLK GD ++SVNG       H
Sbjct: 94  VELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHH 153

Query: 569 AEVVTELKAA 578
            + V  LKAA
Sbjct: 154 EKAVELLKAA 163


>gi|11545920 lin-7 homolog B [Homo sapiens]
          Length = 207

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 5/70 (7%)

Query: 514 VHLTRGEGGFGLTLRG----DSPVLIAAVIPGSQAAA-AGLKEGDYIVSVNGQPCRWWRH 568
           V L + + G G  + G    +SP+ I+ VIPG  A    GLK GD ++SVNG      +H
Sbjct: 94  VELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQH 153

Query: 569 AEVVTELKAA 578
            + V  LKAA
Sbjct: 154 EKAVELLKAA 163


>gi|223890252 glutamate receptor interacting protein 1 [Homo
           sapiens]
          Length = 1076

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 40/155 (25%), Positives = 70/155 (45%), Gaps = 10/155 (6%)

Query: 440 ISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPL 499
           +S   Q  +A  ++     D+ +A    ++    H +  + +  + +    ++ + L P+
Sbjct: 80  VSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEVEYELPPV 139

Query: 500 SVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDS--------PVLIAAVIPGSQAAAAG-LK 550
           SV  +   +R V  V L +    FG  +RG +        PV+I  V PG  A   G +K
Sbjct: 140 SVQGSSVIFRTV-EVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIK 198

Query: 551 EGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASL 585
            GD ++SV+G       HAE ++ LK  G+  A L
Sbjct: 199 PGDRLLSVDGIRLLGTTHAEAMSILKQCGQEAALL 233



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 6/73 (8%)

Query: 514 VHLTRGEGG-FGLTLRG----DSPVLIAAVIPGSQAAAAG-LKEGDYIVSVNGQPCRWWR 567
           V L + EG   GLT+ G    D    ++ +  G  AA +  L  GDYI +VNG     +R
Sbjct: 54  VELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFR 113

Query: 568 HAEVVTELKAAGE 580
           H E+++ LK  GE
Sbjct: 114 HDEIISLLKNVGE 126


>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
          Length = 330

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 16/147 (10%)

Query: 519 GEGGFGLTLRG----DSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTE 574
           G G +G  L+G    + P+ I+ + PGS+AA + L +GD +V+++G       H E   +
Sbjct: 9   GPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNK 68

Query: 575 LKAAGEAGASLQVVSLLPSSRLP-SLGDRRPVLLGPRGLLRSQREHGCKTPASTWA-SPR 632
           +K+     AS  +   L  S+ P  +    P +  P  ++  Q++    T  S  A SP 
Sbjct: 69  IKS-----ASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPS 123

Query: 633 PLLNWSRKAQQGKTGGCPQPCAPVKPA 659
           P      +A  G T G P+      PA
Sbjct: 124 P----EARASPG-TPGTPELRPTFSPA 145


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 16/147 (10%)

Query: 519 GEGGFGLTLRG----DSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTE 574
           G G +G  L+G    + P+ I+ + PGS+AA + L +GD +V+++G       H E   +
Sbjct: 9   GPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNK 68

Query: 575 LKAAGEAGASLQVVSLLPSSRLP-SLGDRRPVLLGPRGLLRSQREHGCKTPASTWA-SPR 632
           +K+     AS  +   L  S+ P  +    P +  P  ++  Q++    T  S  A SP 
Sbjct: 69  IKS-----ASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPS 123

Query: 633 PLLNWSRKAQQGKTGGCPQPCAPVKPA 659
           P      +A  G T G P+      PA
Sbjct: 124 P----EARASPG-TPGTPELRPTFSPA 145


>gi|112382257 InaD-like [Homo sapiens]
          Length = 1801

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 30/59 (50%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 521  GGFGLTLRGDSPVLIAAV-IPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAA 578
            GG G  L GD PV IA +   G  A    LK GD IVS+NGQP     HA+VV  LK A
Sbjct: 1693 GGRGSPL-GDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNA 1750



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 28/71 (39%), Positives = 37/71 (52%), Gaps = 5/71 (7%)

Query: 513  PVHLTRGEG-GFGLTL---RGDSPVLIAAVIPGSQAAAAG-LKEGDYIVSVNGQPCRWWR 567
            PV L +  G G GL++   R  S V I+ ++ G  A   G L +GD I+SVNG+  R   
Sbjct: 1533 PVDLQKKAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNAS 1592

Query: 568  HAEVVTELKAA 578
               V T LK A
Sbjct: 1593 QETVATILKCA 1603



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 6/69 (8%)

Query: 514  VHLTRGEGGFGLTLRGDSPVLIAAVI------PGSQAAAAGLKEGDYIVSVNGQPCRWWR 567
            + +++G  G GL++ G     + A++       G+ A    L  GD I+ VNG   R   
Sbjct: 1438 IEISKGRSGLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSS 1497

Query: 568  HAEVVTELK 576
            H E +T L+
Sbjct: 1498 HEEAITALR 1506



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 3/77 (3%)

Query: 508 WRLVGPVHLTR-GEG-GFGLTLRGDSPVLIAAVIPGSQAAAAG-LKEGDYIVSVNGQPCR 564
           W  V  V L   G G GFG+     S V++  ++PG  A   G L+ GD+I+ + G   +
Sbjct: 243 WGHVEEVELINDGSGLGFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQ 302

Query: 565 WWRHAEVVTELKAAGEA 581
                +V   L+  G +
Sbjct: 303 GMTSEQVAQVLRNCGNS 319


>gi|4759306 lin-7 homolog A [Homo sapiens]
          Length = 233

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 5/73 (6%)

Query: 514 VHLTRGEGGFGLTLRG----DSPVLIAAVIPGSQAAA-AGLKEGDYIVSVNGQPCRWWRH 568
           V L + + G G  + G    +SP+ I+ +IPG  A    GLK GD ++SVNG       H
Sbjct: 109 VELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHH 168

Query: 569 AEVVTELKAAGEA 581
            + V  LKAA ++
Sbjct: 169 EKAVELLKAAKDS 181


>gi|21361142 PDZ domain containing 1 [Homo sapiens]
          Length = 519

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 514 VHLTRGEGGFGLTLRGDSPV---LIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAE 570
           V + +G  G+G  LR  S     +I  +  GS A  AGLK  D +V+VNG+      H  
Sbjct: 244 VEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDS 303

Query: 571 VVTELKAAGEAGASLQV 587
           VV  ++  G+  + L V
Sbjct: 304 VVEMIRKGGDQTSLLVV 320



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 519 GEGGFGL-TLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKA 577
           G  GF L T++G   V +  + P   A  AG+   D+++ VNG+      H EVV ++K 
Sbjct: 143 GSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKK 202

Query: 578 AG 579
           +G
Sbjct: 203 SG 204



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 3/68 (4%)

Query: 516 LTRGEGGFGLTL---RGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVV 572
           L +GE G+G  L   RG     I  V  G  A  AGL++ D I+ VNG       + +VV
Sbjct: 381 LAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVV 440

Query: 573 TELKAAGE 580
             ++++G+
Sbjct: 441 DRIQSSGK 448



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 28/153 (18%)

Query: 516 LTRGEG---GFGLTLRGDSPV-LIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEV 571
           L++ EG   GF L +  D+   L+  V   S A  AGL++GD ++ +NG       H +V
Sbjct: 12  LSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQV 71

Query: 572 VTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKT-------- 623
           V  ++   ++G S+ ++ L   S   ++  R    +  + L +SQ+E G           
Sbjct: 72  VDLVR---KSGNSVTLLVLDGDSYEKAVKTR----VDLKELGQSQKEQGLSDNILSPVMN 124

Query: 624 -PASTWASPR--------PLLNWSRKAQQGKTG 647
               TW  PR            +S K  QGK G
Sbjct: 125 GGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKG 157


>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
          Length = 1109

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 7/80 (8%)

Query: 519 GEGGFGLTLRGDS----PVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTE 574
           G   +G  L+G      P+ +A +   S+A+ +GL EGD +VS+NG PC    + EV+  
Sbjct: 13  GGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKL 72

Query: 575 LKAAGEAGASLQVVSLLPSS 594
           +++  +   SLQ++   PSS
Sbjct: 73  MESITD---SLQMLIKRPSS 89


>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
          Length = 1093

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 7/80 (8%)

Query: 519 GEGGFGLTLRGDS----PVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTE 574
           G   +G  L+G      P+ +A +   S+A+ +GL EGD +VS+NG PC    + EV+  
Sbjct: 13  GGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKL 72

Query: 575 LKAAGEAGASLQVVSLLPSS 594
           +++  +   SLQ++   PSS
Sbjct: 73  MESITD---SLQMLIKRPSS 89


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,359,573
Number of Sequences: 37866
Number of extensions: 1413565
Number of successful extensions: 5600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 5330
Number of HSP's gapped (non-prelim): 328
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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