BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] (389 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] 806 0.0 gi|239742481 PREDICTED: hypothetical protein XP_002342546 [Homo ... 714 0.0 gi|239748510 PREDICTED: hypothetical protein XP_002346712 [Homo ... 660 0.0 gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 8e-11 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 2e-10 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 61 2e-09 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 61 2e-09 gi|153792074 proline rich 12 [Homo sapiens] 61 2e-09 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 60 3e-09 gi|19924099 synapsin I isoform Ia [Homo sapiens] 59 7e-09 gi|19924097 synapsin I isoform Ib [Homo sapiens] 59 7e-09 gi|236459851 ubinuclein 2 [Homo sapiens] 58 1e-08 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 58 1e-08 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 58 2e-08 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 57 2e-08 gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] 57 2e-08 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 57 3e-08 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 57 4e-08 gi|150417989 cyclin K isoform 1 [Homo sapiens] 57 4e-08 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 57 4e-08 gi|7706501 WW domain binding protein 11 [Homo sapiens] 57 4e-08 gi|33356148 formin-like 1 [Homo sapiens] 57 4e-08 gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 56 5e-08 gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 56 5e-08 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 55 8e-08 gi|41281808 harmonin isoform b3 [Homo sapiens] 55 1e-07 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 55 1e-07 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 55 1e-07 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 55 1e-07 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 55 1e-07 >gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] Length = 389 Score = 806 bits (2082), Expect = 0.0 Identities = 389/389 (100%), Positives = 389/389 (100%) Query: 1 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP 60 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP Sbjct: 1 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP 60 Query: 61 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR 120 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR Sbjct: 61 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR 120 Query: 121 PPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQ 180 PPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQ Sbjct: 121 PPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQ 180 Query: 181 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA 240 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA Sbjct: 181 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA 240 Query: 241 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR 300 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR Sbjct: 241 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR 300 Query: 301 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA 360 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA Sbjct: 301 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA 360 Query: 361 AAPASLTDHSFARPLVTEHLAHGVSGAGD 389 AAPASLTDHSFARPLVTEHLAHGVSGAGD Sbjct: 361 AAPASLTDHSFARPLVTEHLAHGVSGAGD 389 >gi|239742481 PREDICTED: hypothetical protein XP_002342546 [Homo sapiens] Length = 359 Score = 714 bits (1842), Expect = 0.0 Identities = 356/389 (91%), Positives = 356/389 (91%), Gaps = 30/389 (7%) Query: 1 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP 60 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP Sbjct: 1 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP 60 Query: 61 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR 120 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR Sbjct: 61 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR 120 Query: 121 PPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQ 180 PPPQAVQPRPSEPTPGSEALPPGSL P Q Sbjct: 121 PPPQAVQPRPSEPTPGSEALPPGSL------------------------------PEAAQ 150 Query: 181 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA 240 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA Sbjct: 151 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA 210 Query: 241 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR 300 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR Sbjct: 211 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR 270 Query: 301 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA 360 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA Sbjct: 271 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA 330 Query: 361 AAPASLTDHSFARPLVTEHLAHGVSGAGD 389 AAPASLTDHSFARPLVTEHLAHGVSGAGD Sbjct: 331 AAPASLTDHSFARPLVTEHLAHGVSGAGD 359 >gi|239748510 PREDICTED: hypothetical protein XP_002346712 [Homo sapiens] Length = 336 Score = 660 bits (1703), Expect = 0.0 Identities = 335/389 (86%), Positives = 335/389 (86%), Gaps = 53/389 (13%) Query: 1 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP 60 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP Sbjct: 1 MTPLPLHLEQDKPGTFRNNGEKKGVDDPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIP 60 Query: 61 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR 120 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR Sbjct: 61 GNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTR 120 Query: 121 PPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQ 180 PPPQAVQPRPSEPTPGSEALPPGSLPE Sbjct: 121 PPPQAVQPRPSEPTPGSEALPPGSLPE--------------------------------- 147 Query: 181 PPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA 240 VRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA Sbjct: 148 --------------------VRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLA 187 Query: 241 PQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNR 300 PQRGRGGLLLVVLHAATVQRPRLGRGPSR PRGPVGVCRPQVAQRQRLARVCVRSLPGNR Sbjct: 188 PQRGRGGLLLVVLHAATVQRPRLGRGPSRQPRGPVGVCRPQVAQRQRLARVCVRSLPGNR 247 Query: 301 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA 360 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA Sbjct: 248 RLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQPAHLSHA 307 Query: 361 AAPASLTDHSFARPLVTEHLAHGVSGAGD 389 AAPASLTDHSFARPLVTEHLAHGVSGAGD Sbjct: 308 AAPASLTDHSFARPLVTEHLAHGVSGAGD 336 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 65.5 bits (158), Expect = 8e-11 Identities = 71/256 (27%), Positives = 91/256 (35%), Gaps = 28/256 (10%) Query: 104 SPADPAAPPSSPH-APTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYAL---PPRE 159 +P PAA P SP P P P+ P+ P + P P+G P P A+ P+ Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021 Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQP-----PSRPAFRSPRPVRGP--HPRRAVVV 212 SPA PF G PA P P PAA P P+ PA P P GP + Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081 Query: 213 AVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLL------LVVLHAATVQRPRLGRG 266 +P+ A + P P +GGL AAT P+ G Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141 Query: 267 PSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFP--LQGGATLPSSLP 324 P P + + LA + P + PAA P +GG PS Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAP--------TTPAATPPSPKGGLATPSPKG 1193 Query: 325 APRLHLGSLLPSSSGG 340 AP + PS GG Sbjct: 1194 APTTP-AATPPSPKGG 1208 Score = 54.3 bits (129), Expect = 2e-07 Identities = 65/249 (26%), Positives = 88/249 (35%), Gaps = 35/249 (14%) Query: 100 TLPVSPADPAAPPSSPHAPTRPPPQAVQPR--PSEPTPGSEALPPGSLPEGEPRPYALPP 157 TLP SP A PS APT P P+ P+ P+P +PP + P A PP Sbjct: 1063 TLP-SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121 Query: 158 RESPAPRPFRWGDPFSPAPPRPQPPSRPAAQP----PSRPAFRSPRPVRG---PHPRRAV 210 + G P +PA P P A P P+ PA P P G P P+ A Sbjct: 1122 HK---------GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172 Query: 211 VVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRP 270 +P+ +A + P P +GGL A P Sbjct: 1173 TTPAA-TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA----PTTPAATPPS 1227 Query: 271 PRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPRLHL 330 P+G + P+ A + P + + PA P +G T P++ P P L Sbjct: 1228 PKGGLATPSPKGAP----------TTPAATPPSPKGGPATPPPKGAPTPPAATP-PSLKG 1276 Query: 331 GSLLPSSSG 339 G P G Sbjct: 1277 GLATPPHKG 1285 Score = 53.9 bits (128), Expect = 2e-07 Identities = 53/203 (26%), Positives = 72/203 (35%), Gaps = 21/203 (10%) Query: 56 ADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSP 115 A P P A A + ++++P + + + AP P SP A PS Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960 Query: 116 HAPTRPPPQAVQPR--PSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFS 173 APT P P+ P+ P+P PP + P P P P SP G P Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATP---PSPKGGPATPSPK------GAPTP 1011 Query: 174 PAPPRPQPPSRPAAQPPSRPAFRSP---------RPVRGPHPRRAVVVAVLFGVQAPRRD 224 PA P P PAA P + A P P P P+ A + +P+ Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA-TLPSPKGG 1070 Query: 225 VAEGGLRRDGRRPGLAPQRGRGG 247 A L+ P P +GG Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGG 1093 Score = 53.5 bits (127), Expect = 3e-07 Identities = 74/301 (24%), Positives = 108/301 (35%), Gaps = 39/301 (12%) Query: 49 PSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSP--- 105 PS LA P P A A T + P + A ++ P + L P Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG 1285 Query: 106 -ADPAA--PPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRES-- 160 +PA PPS P PP+ P+ P + P P+G P P A+ P Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345 Query: 161 ----PAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSR--PAFRSPRPVRG---PHPR---R 208 PA P G P +P+ + P+ PAA P + PA P P RG P P+ Sbjct: 1346 TPTLPATTPSSKGGPTTPSSK--EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403 Query: 209 AVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPS 268 + V L +AP V G A +G L + ++++ P Sbjct: 1404 SPAVIPLSPKKAPATPVTREG----------AATPSKGDLTPPAVTPVSLKKAPATSAPK 1453 Query: 269 RPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPL----QGGATLPSSLP 324 P P P + + + P +++AT S P P G TLP+ +P Sbjct: 1454 GGPATPSSKGDPTL---PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510 Query: 325 A 325 + Sbjct: 1511 S 1511 Score = 48.5 bits (114), Expect = 1e-05 Identities = 81/302 (26%), Positives = 100/302 (33%), Gaps = 64/302 (21%) Query: 49 PSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADP 108 PS LA P P A A T + P + AP P SP Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK--------GAPTTPAATPPSPKGG 1185 Query: 109 AAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP-RPYALPPR-----ESPA 162 A PS APT P P+ TP P+G P P A PP +P+ Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPS---------PKGAPTTPAATPPSPKGGLATPS 1236 Query: 163 PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPR 222 P+ G P +PA P P PA PP +P P P +A AP Sbjct: 1237 PK----GAPTTPAATPPSPKGGPATPPPK----GAPTPPAATPPSLKGGLATPPHKGAPN 1288 Query: 223 RDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRG---PVGVCR 279 V + G P +P +G AAT P+ G + PP+G P V Sbjct: 1289 PAVVTPPSPKGG--PATSPPKG-----APTPPAATPPSPK-GSPGTPPPKGAPTPPAVTP 1340 Query: 280 PQVAQRQRLARVCVRSLPGNRRLATRSCPAAFP-LQGGATLPSSLPAPRLHLGSLLPSSS 338 P T + PA P +GG T PSS P + PS Sbjct: 1341 PSPK-------------------GTPTLPATTPSSKGGPTTPSSKEGPTPPAAT--PSHK 1379 Query: 339 GG 340 GG Sbjct: 1380 GG 1381 Score = 47.4 bits (111), Expect = 2e-05 Identities = 81/311 (26%), Positives = 99/311 (31%), Gaps = 69/311 (22%) Query: 94 APWRELTLPVSPADPAAPPSSPHAPT--------------RPPPQAVQPRPSEPTP---G 136 AP P SP A P APT PPP+ P+ P G Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161 Query: 137 SEALPPGSLPEGEP-RPYALPPR-----ESPAPRPFRWGDPFSPAPPRPQP--------- 181 A PP P+G P P A PP +P+P+ G P +PA P P Sbjct: 1162 GLATPP---PKGAPTTPAATPPSPKGGLATPSPK----GAPTTPAATPPSPKGGLATPSP 1214 Query: 182 ---PSRPAAQPPS-RPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRP 237 P+ PAA PPS + +P P P A + G P A P Sbjct: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP-------TPP 1267 Query: 238 GLAPQRGRGGLLLV----VLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCV 293 P +GGL + A V P GP+ P P G P A Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPTPPAA---------- 1315 Query: 294 RSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAGTTHFQ 353 + P + P P T PS P L + PSS GG + Sbjct: 1316 -TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT--LPATTPSSKGGPTTPSSKEGPTPP 1372 Query: 354 PAHLSHAAAPA 364 A SH PA Sbjct: 1373 AATPSHKGGPA 1383 Score = 45.4 bits (106), Expect = 9e-05 Identities = 67/271 (24%), Positives = 95/271 (35%), Gaps = 42/271 (15%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYA------- 154 P +P + P SP + P ++ + S+ +P + P P+G P P A Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876 Query: 155 ---LPPRESPAPR----PFRWGDPFSPAPPR-------PQPPSRPAAQPPSRPAFRSPRP 200 LPP+E+P P PF P +PAP + P + A P + SP P Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936 Query: 201 VRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLL------LVVLH 254 P P A + G P A P P +GG Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAP-------TPPAATPPSPKGGPATPSPKGAPTPP 989 Query: 255 AATVQRPRLGRGPSRPPRGP----VGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAA 310 AAT P+ G P P V P+ + + P + + PAA Sbjct: 990 AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049 Query: 311 FPLQGGA--TLPSSLPAPRLHLGSLLPSSSG 339 PL GA T ++LP+P+ G PS G Sbjct: 1050 TPLPKGAPTTPAATLPSPK--GGPATPSLKG 1078 Score = 42.7 bits (99), Expect = 6e-04 Identities = 33/119 (27%), Positives = 47/119 (39%), Gaps = 10/119 (8%) Query: 94 APWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPR-PSEPTPGSEALPPG-SLPEGEPR 151 AP +P SP + A PSS P P + + P+ P +PP ++P + Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561 Query: 152 PYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSR----PAFRSPRPVRGPHP 206 P P+E+PA + +PP P + A P PA SP P P P Sbjct: 1562 PAIPTPKEAPATP----SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616 Score = 40.4 bits (93), Expect = 0.003 Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 5/120 (4%) Query: 97 RELTLPVSPADPAAPPSSPHAPTRPP--PQAVQPRPSEPTPGSEALPPGSLPEGEPRPYA 154 +++ SP A P+ APT P P + + P+ P+ + + P + + P Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPAT 1541 Query: 155 LPPRESPAPRPFRWGDP-FSPAPPRP-QPPSRPAAQPPSRPAFRSPRPVRG-PHPRRAVV 211 L P+E+ P P +PA P P + P+ P+++ S P +P +G P P+ ++ Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601 Score = 39.7 bits (91), Expect = 0.005 Identities = 67/260 (25%), Positives = 87/260 (33%), Gaps = 44/260 (16%) Query: 48 VPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVS--- 104 VPS + A P P A A + E SSPP ++Y S +EL +P + Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEA-----SSPPAVTPSTYKGAPSP--KELLIPPAVTS 1607 Query: 105 ------PADPAAPPSSPH----------APTRPPPQAVQPRPSEPTPGSEALPPG-SLPE 147 P PA P SP PT PP + S +P S G ++P+ Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667 Query: 148 GEPRPYALPPRESP--------APRPFRWGDPFSPAPPR--PQPPSRPAAQPPSRPAFRS 197 LP ++ P AP P P AP R PQ A PP P + Sbjct: 1668 ASK---GLPAKKGPTALKEVLVAPAP--ESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722 Query: 198 PRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAAT 257 +G P V A L VQ A+G + LAP + L Sbjct: 1723 KNGSKG--PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780 Query: 258 VQRPRLGRGPSRPPRGPVGV 277 V S P PV + Sbjct: 1781 VLPKPESASVSAAPSPPVSL 1800 Score = 38.5 bits (88), Expect = 0.010 Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 19/116 (16%) Query: 104 SPADPAAPPSSPHAP--TRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESP 161 SP P APP S + T + V P+P + + PP SLP LPP++ Sbjct: 1757 SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ- 1815 Query: 162 APRPFRWGDPFSPAPP-----RPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVV 212 F P+ P P P PA + P P P+ G P ++V+V Sbjct: 1816 ----------FLPSSPGLVLESPSKPLAPADEDELLPLI-PPEPISGGVPFQSVLV 1860 Score = 32.7 bits (73), Expect = 0.57 Identities = 37/138 (26%), Positives = 49/138 (35%), Gaps = 13/138 (9%) Query: 68 ARTEQRDHSQSSP--PCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQA 125 A+ + HS P P AS ++A + L P S + AAP P P P Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVP 1808 Query: 126 VQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESP-----APRPFRWGDPFSPAPPRPQ 180 P + P S PG + E +P A P E P P G PF Sbjct: 1809 TLPPKQQFLPSS----PGLVLESPSKPLA-PADEDELLPLIPPEPISGGVPFQSVLVN-M 1862 Query: 181 PPSRPAAQPPSRPAFRSP 198 P + A P P+ + P Sbjct: 1863 PTPKSAGIPVPTPSAKQP 1880 Score = 32.3 bits (72), Expect = 0.75 Identities = 35/122 (28%), Positives = 45/122 (36%), Gaps = 13/122 (10%) Query: 59 IPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAP 118 +PG A V TEQ P + + SSA +T + P PP AP Sbjct: 1 MPGEATETVPATEQE-----LPQPQAETAVLPMSSA--LSVTAALGQPGPTLPPPCSPAP 53 Query: 119 TRPPPQAVQPRPSEPTPGSEALPPGSLP-----EGEPRPYALPPRESPAPRPFRWGDPFS 173 + P A P+P + A P +P G P P E+P P G P S Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP-EAPTFLPNLIGPPIS 112 Query: 174 PA 175 PA Sbjct: 113 PA 114 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 63.9 bits (154), Expect = 2e-10 Identities = 93/356 (26%), Positives = 122/356 (34%), Gaps = 56/356 (15%) Query: 78 SSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHA--PTRPPPQAVQPRPSEPTP 135 +SPP A+ + P L V P+ PA+PP SP A P R PP P P Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771 Query: 136 GSEALPPGSL---PEGEPRPYALPPRES--PAPRPFRWGDPFSP---------APPRPQP 181 +LP L P P A PP ++ P F PFSP A P PQ Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831 Query: 182 PSRPAA-------QPPSRPAFRSPRPVRGPHPRRAV-----VVAVLFG-----VQAPRRD 224 P AA PP+ P ++PR P P +V +A+ G ++P Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891 Query: 225 VAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQ 284 ++ L P+ RG P G S PP + C P Sbjct: 892 LSGPDLAGHSSSATSTPEELRG----------YDSGPEGGAAASPPPDAELAACHPAAWS 941 Query: 285 RQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATL------PSSLPAPRLHLGSLLPSSS 338 R + R PG L G T+ S+ PAP P +S Sbjct: 942 RGPAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 1000 Query: 339 GG-ARLGDAAGTTHFQP-----AHLSHAAAPASLTDHSFARPLVTEHLAHGVSGAG 388 GG A G AG + P L A AS+ H +R L+ G+G Sbjct: 1001 GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 1056 Score = 57.0 bits (136), Expect = 3e-08 Identities = 47/126 (37%), Positives = 56/126 (44%), Gaps = 11/126 (8%) Query: 78 SSPPCRRLASYSFWSSAP----WRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEP 133 +SPP LA+ S AP L P SP P+ P +P +P PP + P Sbjct: 638 ASPPLSPLATPS--PQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQ 694 Query: 134 TPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRP 193 P S A PP +P P P A PP SP+ P P APP PPS PA+ P S Sbjct: 695 APPSLAAPPLQVP---PSPPASPPM-SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750 Query: 194 AFRSPR 199 A PR Sbjct: 751 ATPPPR 756 Score = 55.5 bits (132), Expect = 8e-08 Identities = 97/363 (26%), Positives = 129/363 (35%), Gaps = 53/363 (14%) Query: 39 PLAAGGRCRVPS-GLRRLADPIPGNARAGV-ARTEQRDHSQSSPPCRRLASYSFWSSAPW 96 P A GG R S L A P+ AR+G AR R + S P + + P Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK----GLQALRP- 282 Query: 97 RELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALP 156 ++T P A PA P S P P + RP P + P +LP P LP Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342 Query: 157 -PRESPAPRPFRWGDPFSPA-PPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAV 214 SP+ P P PA PP PPS + P+ ++ P++ PH + Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP---- 398 Query: 215 LFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGR----GPSRP 270 +QAP +A L+ G L H+ PR + PSRP Sbjct: 399 --SLQAPPSPLALSSLQ---------ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447 Query: 271 PRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLP-----SSLP- 324 P P Q SLP + L T PA PL T+ SSL Sbjct: 448 ASTP-----PDSPPLQ-----APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497 Query: 325 -APRLHLGSLL------PSSSGGARLGDAAGTTHFQPAHLSHAAAPASLTDHSFARPLVT 377 +P+ L SL+ SS L + P + AP L + + PL T Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--QTASAPLTT 555 Query: 378 EHL 380 HL Sbjct: 556 PHL 558 Score = 53.9 bits (128), Expect = 2e-07 Identities = 74/280 (26%), Positives = 101/280 (36%), Gaps = 51/280 (18%) Query: 76 SQSSPPCRRLASYS----FWSSAPWRELTLPVSPADPAAPPSSPHAP-TRPPPQ---AVQ 127 S ++PP L S + +SAP L P P +P +P T PPP+ ++ Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588 Query: 128 PRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAA 187 P + P + P LP P A PP ++P P PP PPS PA+ Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP---------PXLALPPLQAPPSPPAS 639 Query: 188 QPPSRPAFRSPRPVRGPHPRRAVVVAVLFG------VQAPRRDVAEGGLRRDGRRPGLAP 241 P S A SP + P+ ++ F VQAP A + P AP Sbjct: 640 PPLSPLATPSP---QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696 Query: 242 QRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRR 301 L A +Q P P+ PP P PQ + V P Sbjct: 697 PS---------LAAPPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP---- 741 Query: 302 LATRSCPAAFPLQGGATLPSSLP----APRLHLGSLLPSS 337 PA+ P+ AT P +P AP L + P+S Sbjct: 742 ------PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS 775 Score = 52.8 bits (125), Expect = 5e-07 Identities = 80/325 (24%), Positives = 116/325 (35%), Gaps = 61/325 (18%) Query: 27 DPQLALNLLLFLPLAAGGRCRVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLA 86 D AL L PLA PSG + P P NA + T PP LA Sbjct: 291 DAAPALGPLSSSPLATPS----PSGTKARPVPPPDNAATPLPAT--------LPPSPPLA 338 Query: 87 SYSFWSSAPWRELTLPVSPADPAAPPS---SPHAPTRPPPQA---VQPRPSEPTPGSEAL 140 + LP++P P+APPS P P PP QA + P + P + + Sbjct: 339 T------------PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386 Query: 141 PPGSLP--------EGEPRPYALPPRE------SPAPRPFRWGDPFSPAPPRPQ--PPSR 184 PP +P + P P AL + SP + SP + PSR Sbjct: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446 Query: 185 PAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRG 244 PA+ PP P ++P + P + + + + +P + L+ +PQ Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP---LTIHPLQALSSLASHSPQAP 503 Query: 245 RGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPG---NRR 301 L++ L + P + P P + P + LA +++ Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTP------PASLTTPPLENLPSLAPPPLQTASAPLTTPH 557 Query: 302 LATRSCPAAFPLQGGATLPSSLPAP 326 L T CPA PLQ PS L P Sbjct: 558 LETPPCPAPCPLQAP---PSPLTTP 579 Score = 40.0 bits (92), Expect = 0.004 Identities = 60/243 (24%), Positives = 86/243 (35%), Gaps = 51/243 (20%) Query: 111 PPSSPHA-PTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWG 169 P S+P A PTR + G+ + P S P R PP ++ +P P Sbjct: 71 PESAPRAGPTR-------------SAGTSSRNPASRPPASGRGERAPPAKNTSPGPV--- 114 Query: 170 DPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGG 229 +P R +RP P +G VA +AP+R G Sbjct: 115 ----SSPGRASGTTRP-----------GPLGQKGLRISAEETVARGKATEAPKRSALSAG 159 Query: 230 LRRD--GRRPG-----LAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPV------G 276 RRD G PG +A + G + + A RP R P+ PR V Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSSASEHS 216 Query: 277 VCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPS 336 P A R+R + P +R L++ + P + P + G PS+ PR P Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQPK 273 Query: 337 SSG 339 G Sbjct: 274 PKG 276 Score = 35.0 bits (79), Expect = 0.12 Identities = 59/240 (24%), Positives = 77/240 (32%), Gaps = 48/240 (20%) Query: 13 PGTFRNNGEKKGVDDP----QLALNLLLFLPLAAGGRCRVP------SGLRR-LADPIPG 61 PG + G G P Q L + +A G P +G RR + P PG Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170 Query: 62 NARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRP 121 +AR + ++ P ++ + R+ S P SP A RP Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRP 228 Query: 122 PPQAVQPRP------SEPTPGSEALPPGSLPEGEPR------------------PYALPP 157 RP S TP S G G PR P PP Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288 Query: 158 RESPAPR--PFRWGDPFSPAP----PRPQPPSRPAAQP-----PSRPAFRSPRPVRGPHP 206 R+ AP P +P+P RP PP AA P P P +P P+ P P Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348 Score = 28.9 bits (63), Expect = 8.3 Identities = 54/196 (27%), Positives = 69/196 (35%), Gaps = 32/196 (16%) Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQ 219 +PA R P P PRP PP PAA R + R P RA + G Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAA---LRVLGAAGAVGRKPLAERAGGIG---GAT 69 Query: 220 APRRDVAEGGLRRDG---RRP-GLAPQRGRGGLLLVVLHAA--TVQRPRLGRGPSRPPRG 273 P G R G R P P GRG + + V P G +RP G Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP--G 127 Query: 274 PVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPRLHLGSL 333 P+G +++ + +AR P L GA +S P P G+ Sbjct: 128 PLGQKGLRISAEETVARG-----------KATEAPKRSALSAGARRDTSGPTP----GTP 172 Query: 334 LPSSSGGARLGDAAGT 349 P+ AR AAGT Sbjct: 173 SPAM---ARRSRAAGT 185 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 61.2 bits (147), Expect = 2e-09 Identities = 89/332 (26%), Positives = 110/332 (33%), Gaps = 67/332 (20%) Query: 101 LPVSPADPAAPPSSPHA---PTRPPP------QAVQPRPSEP----TPGSEALP--PGSL 145 L V P+ PA+PP SP A P PPP Q +P P P TP +ALP P S Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538 Query: 146 PEGEP---------RPYALPPRESPA--PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPA 194 P P P A PP ++P P P PA P Q P RP P + Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD-TS 597 Query: 195 FRSPR------PVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGL 248 PR P P P R +P ++ L P+ RG Sbjct: 598 VSGPRLTLALAPGPPPPPSR-----------SPSSTLSGPDLAGHSSSATSTPEELRG-- 644 Query: 249 LLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCP 308 P G S PP + C P R + R PG L Sbjct: 645 --------YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG-APLPWPPAT 695 Query: 309 AAFPLQGGATL------PSSLPAPRLHLGSLLPSSSGG-ARLGDAAGTTHFQP-----AH 356 G T+ S+ PAP P +SGG A G AG + P Sbjct: 696 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 755 Query: 357 LSHAAAPASLTDHSFARPLVTEHLAHGVSGAG 388 L A AS+ H +R L+ G+G Sbjct: 756 LPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 787 Score = 55.8 bits (133), Expect = 6e-08 Identities = 68/237 (28%), Positives = 91/237 (38%), Gaps = 36/237 (15%) Query: 101 LPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPP--GSLPEGEPRPYALPPR 158 LP++P P+APPS T P P A P + + GS L LP P A PP Sbjct: 338 LPLAPPSPSAPPS---LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394 Query: 159 ESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFG- 217 ++P P PP PPS PA+ P S A SP + P+ ++ F Sbjct: 395 QAP---------PALALPPLQAPPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFSP 442 Query: 218 -----VQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLH--AATVQRPRLGRGPSRP 270 VQAP A + P AP L V A+ P P P Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502 Query: 271 P---RGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLP 324 P P+ + +P LA +++LP S PA+FP Q + +SLP Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALP--------SPPASFPGQAPFSPSASLP 551 Score = 41.6 bits (96), Expect = 0.001 Identities = 78/288 (27%), Positives = 99/288 (34%), Gaps = 40/288 (13%) Query: 62 NARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRP 121 +A G+ R R S S+ P A S P T P +PA P+ P RP Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPAR-----SGPSARGT-PRAPAHPSQPKPKGLQALRP 282 Query: 122 PPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSP------A 175 P + + P G P S P P P A ++P P P S A Sbjct: 283 PQVTPPRKDAAPALG----PLSSSPLATPSPSAALQSQAPPTLP---ATPHSSSLTCQLA 335 Query: 176 PPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGR 235 P P P P+A PPS SP P +A +QA + L Sbjct: 336 TPLPLAPPSPSA-PPSLQTLPSP---PATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391 Query: 236 RPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQV--AQRQRLARVCV 293 P AP L +Q P P+ PP P+ PQ A L + Sbjct: 392 PPPQAPP---------ALALPPLQAP--PSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440 Query: 294 RSLPGNRRLATRSCPAAFPLQGGATLPS----SLPAPRLHLGSLLPSS 337 P A S PA+ P+ AT PS SL AP L + P+S Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488 Score = 40.0 bits (92), Expect = 0.004 Identities = 60/243 (24%), Positives = 86/243 (35%), Gaps = 51/243 (20%) Query: 111 PPSSPHA-PTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWG 169 P S+P A PTR + G+ + P S P R PP ++ +P P Sbjct: 71 PESAPRAGPTR-------------SAGTSSRNPASRPPASGRGERAPPAKNTSPGPV--- 114 Query: 170 DPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGG 229 +P R +RP P +G VA +AP+R G Sbjct: 115 ----SSPGRASGTTRP-----------GPLGQKGLRISAEETVARGKATEAPKRSALSAG 159 Query: 230 LRRD--GRRPG-----LAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPV------G 276 RRD G PG +A + G + + A RP R P+ PR V Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSSASEHS 216 Query: 277 VCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPS 336 P A R+R + P +R L++ + P + P + G PS+ PR P Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQPK 273 Query: 337 SSG 339 G Sbjct: 274 PKG 276 Score = 34.7 bits (78), Expect = 0.15 Identities = 51/205 (24%), Positives = 72/205 (35%), Gaps = 30/205 (14%) Query: 13 PGTFRNNGEKKGVDDP----QLALNLLLFLPLAAGGRCRVP------SGLRR-LADPIPG 61 PG + G G P Q L + +A G P +G RR + P PG Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170 Query: 62 NARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRP 121 +AR + ++ P ++ + R+ S P SP A RP Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRP 228 Query: 122 PPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPA-PPRPQ 180 RP+ + S A P S P R P+ R G P +PA P +P+ Sbjct: 229 SAGGGLQRPASRSLSSSATPLSS-----------PARSGPSAR----GTPRAPAHPSQPK 273 Query: 181 PPSRPAAQPPS-RPAFRSPRPVRGP 204 P A +PP P + P GP Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGP 298 Score = 28.9 bits (63), Expect = 8.3 Identities = 54/196 (27%), Positives = 69/196 (35%), Gaps = 32/196 (16%) Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQ 219 +PA R P P PRP PP PAA R + R P RA + G Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAA---LRVLGAAGAVGRKPLAERAGGIG---GAT 69 Query: 220 APRRDVAEGGLRRDG---RRP-GLAPQRGRGGLLLVVLHAA--TVQRPRLGRGPSRPPRG 273 P G R G R P P GRG + + V P G +RP G Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP--G 127 Query: 274 PVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPRLHLGSL 333 P+G +++ + +AR P L GA +S P P G+ Sbjct: 128 PLGQKGLRISAEETVARG-----------KATEAPKRSALSAGARRDTSGPTP----GTP 172 Query: 334 LPSSSGGARLGDAAGT 349 P+ AR AAGT Sbjct: 173 SPAM---ARRSRAAGT 185 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 61.2 bits (147), Expect = 2e-09 Identities = 89/332 (26%), Positives = 110/332 (33%), Gaps = 67/332 (20%) Query: 101 LPVSPADPAAPPSSPHA---PTRPPP------QAVQPRPSEP----TPGSEALP--PGSL 145 L V P+ PA+PP SP A P PPP Q +P P P TP +ALP P S Sbjct: 440 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499 Query: 146 PEGEP---------RPYALPPRESPA--PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPA 194 P P P A PP ++P P P PA P Q P RP P + Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD-TS 558 Query: 195 FRSPR------PVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGL 248 PR P P P R +P ++ L P+ RG Sbjct: 559 VSGPRLTLALAPGPPPPPSR-----------SPSSTLSGPDLAGHSSSATSTPEELRG-- 605 Query: 249 LLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCP 308 P G S PP + C P R + R PG L Sbjct: 606 --------YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG-APLPWPPAT 656 Query: 309 AAFPLQGGATL------PSSLPAPRLHLGSLLPSSSGG-ARLGDAAGTTHFQP-----AH 356 G T+ S+ PAP P +SGG A G AG + P Sbjct: 657 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 716 Query: 357 LSHAAAPASLTDHSFARPLVTEHLAHGVSGAG 388 L A AS+ H +R L+ G+G Sbjct: 717 LPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 748 Score = 55.5 bits (132), Expect = 8e-08 Identities = 88/307 (28%), Positives = 120/307 (39%), Gaps = 34/307 (11%) Query: 39 PLAAGGRCRVPS-GLRRLADPIPGNARAGVAR--TEQRDHSQSSPPCRRLASYSFWSSAP 95 P A GG R S L A P+ AR+G + T + S P + L + P Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278 Query: 96 WRELTLP----VSPADPAAP-PSSPHAPTRPPPQAVQPRPSEP-TPGSEALPPGSLPEGE 149 R+ P +S + A P PS+P +P+ PP ++Q PS P TP S+A P + Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP--SLQTLPSPPATPPSQATTSLGSPTLQ 336 Query: 150 PRPYALP-PRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRR 208 LP P SP P P PP PPS PA+ P S A SP + P+ Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP---QAPNALA 393 Query: 209 AVVVAVLFG------VQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLH--AATVQR 260 ++ F VQAP A + P AP L V A+ Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453 Query: 261 PRLGRGPSRPP---RGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGA 317 P P PP P+ + +P LA +++LP S PA+FP Q Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--------SPPASFPGQAPF 505 Query: 318 TLPSSLP 324 + +SLP Sbjct: 506 SPSASLP 512 Score = 38.5 bits (88), Expect = 0.010 Identities = 88/356 (24%), Positives = 116/356 (32%), Gaps = 39/356 (10%) Query: 13 PGTFRNNGEKKGVDDP----QLALNLLLFLPLAAGGRCRVP------SGLRR-LADPIPG 61 PG + G G P Q L + +A G P +G RR + P PG Sbjct: 102 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161 Query: 62 NARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRP 121 +AR + ++ P ++ + R+ S P SP A RP Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRP 219 Query: 122 PPQAVQPRP------SEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPA 175 RP S TP S G G PR A P P P+ + P Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVT 277 Query: 176 PPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGR 235 PPR + PA P S +P P P P + L A A L Sbjct: 278 PPRKD--AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335 Query: 236 R--------PGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQV--AQR 285 + P L+P L +Q P P+ PP P+ PQ A Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAP--PSPPASPPLSPLATPSPQAPNALA 393 Query: 286 QRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPS----SLPAPRLHLGSLLPSS 337 L + P A S PA+ P+ AT PS SL AP L + P+S Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 Score = 32.7 bits (73), Expect = 0.57 Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 38/179 (21%) Query: 59 IPGNA-RAGVARTEQRDHS---QSSPPCRRLASYSFWSSA---------PWRELTLPVSP 105 IP +A RAG RT + S + +PP + + S P + L +S Sbjct: 70 IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129 Query: 106 ADPAAPPSSPHAPTRPPPQAVQ------PRPSEPTP---------GSEALPPGSLPEGEP 150 + A + AP R A P P P+P G+E P P P Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189 Query: 151 RPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAA-----QPPSRPAFRSPRPVRGP 204 RP PR+S + S P P RP+A +P SR S P+ P Sbjct: 190 RPPTEGPRKSVSS-----ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 Score = 32.3 bits (72), Expect = 0.75 Identities = 72/258 (27%), Positives = 84/258 (32%), Gaps = 71/258 (27%) Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQ--------------------------PPSRP 193 +PA R P P PRP PP PAA P S P Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75 Query: 194 AFRSPRPVRGPHPRRAVVVAVLFGVQA-PRRDVAEGGLRRDGR-----RPGLAPQRG-RG 246 R R P R G +A P ++ + G + GR RPG Q+G R Sbjct: 76 RAGPTRTSRPPASGR--------GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127 Query: 247 GLLLVVLHAATVQRPR---LGRGPSRPPRGPV-GVCRPQVAQRQRLARVCV---RSLPGN 299 V + P+ L G R GP G P +A+R R A V R P Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187 Query: 300 R-----------------RLATRSCPAA--FPLQGGATLPSSLPAPRLHLGSLLPSSSGG 340 R T PAA P GG PA R S P SS Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---QRPASRSLSSSATPLSS-P 243 Query: 341 ARLGDAAGTTHFQPAHLS 358 AR G +A T PAH S Sbjct: 244 ARSGPSARGTPRAPAHPS 261 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 60.8 bits (146), Expect = 2e-09 Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 8/105 (7%) Query: 104 SPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAP 163 +P P P PT PP QP+P P P + P P P P + PP P P Sbjct: 1447 TPEPPLLEEKPP--PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504 Query: 164 RPFRWGDPFSPAPPRPQPP-SRPAAQPPSRPAFRSPRPVRGPHPR 207 P P P+PP P PP + P A PP PA SP P R Sbjct: 1505 PP-----PAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTR 1544 Score = 56.2 bits (134), Expect = 5e-08 Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 5/94 (5%) Query: 108 PAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFR 167 P PP +P +PPP P+P+ P+P P S P P P PP P+P P Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP-PPPAMPSPPP-- 1514 Query: 168 WGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPV 201 P A P PP PAA P P RP+ Sbjct: 1515 --PPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 18/105 (17%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESP 161 P + P PP +P A PP P P P+ S P L E +P PP P Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPP----PLPGLPSANSNGTPEPPLLEEKP-----PPTPPP 1463 Query: 162 APRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 AP P P PP P PP +PA PS P +P P P P Sbjct: 1464 APTP-------QPQPPPPPPPPQPAL--PSPPPLVAPTPSSPPPP 1499 Score = 52.4 bits (124), Expect = 7e-07 Identities = 36/103 (34%), Positives = 49/103 (47%), Gaps = 16/103 (15%) Query: 102 PVSPADPA-APPSSPHAPTR-----PPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYAL 155 P++PA PP P P+ P P ++ +P PTP PP P+ +P P Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP-PTP-----PPAPTPQPQPPPPPP 1476 Query: 156 PPRES-PAPRPFRWGDPFSPAPPR---PQPPSRPAAQPPSRPA 194 PP+ + P+P P P SP PP P PP+ P+ PP PA Sbjct: 1477 PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPA 1519 Score = 48.9 bits (115), Expect = 8e-06 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 21/132 (15%) Query: 58 PIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHA 117 P+PG A T + + PP + P P P P PP P Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPP----------PTPPPAPTPQPQPPPPP--PPPQPAL 1482 Query: 118 PTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPP 177 P+ PP V P PS P P PP P P P PP PA P P PA P Sbjct: 1483 PS--PPPLVAPTPSSPPPPPLPPPP---PPAMPSP---PPPPPPAAAPLA-APPEEPAAP 1533 Query: 178 RPQPPSRPAAQP 189 P+ P P +P Sbjct: 1534 SPEDPELPDTRP 1545 Score = 42.7 bits (99), Expect = 6e-04 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 24/112 (21%) Query: 95 PWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYA 154 PW +PV + A P S + PPP+A P P TP E Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETP-------------EKTTSE 1712 Query: 155 LPPRESPAPRPFRWGDPFSPAPPRPQPPS--RPAAQPPSR-PAFRSPRPVRG 203 PP ++P + P PP P+ PS RP + + R RP+RG Sbjct: 1713 KPPEQTP--------ETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRG 1756 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/106 (34%), Positives = 40/106 (37%), Gaps = 28/106 (26%) Query: 108 PAAPPSSPHAPTRPP--PQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRP 165 P A P P PP P A P P P PG P + G P P P E P Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPP-PLPGL----PSANSNGTPEP---PLLEEKPP-- 1458 Query: 166 FRWGDPFSPAPPR-----PQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 P PP PQPP P PP +PA SP P+ P P Sbjct: 1459 --------PTPPPAPTPQPQPPPPP---PPPQPALPSPPPLVAPTP 1493 Score = 36.6 bits (83), Expect = 0.040 Identities = 33/116 (28%), Positives = 41/116 (35%), Gaps = 12/116 (10%) Query: 107 DPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPF 166 +PA +P P PPP P P P L L P P L P ES P P Sbjct: 825 EPATRDGAPQPPPPPPP----PPPPMPLQLEAHLRSHGLEPAAPSP-RLRPEESLDP-PG 878 Query: 167 RWGDPFSPAPPRPQPPSRPAAQPPSRP------AFRSPRPVRGPHPRRAVVVAVLF 216 + P P P PP+ A+RSP P PR + ++ F Sbjct: 879 AMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICF 934 Score = 35.0 bits (79), Expect = 0.12 Identities = 69/281 (24%), Positives = 95/281 (33%), Gaps = 58/281 (20%) Query: 76 SQSSPPCRRLASYSFWSSAPWRELTLPVSPA---DPAAPPS----SPHAPTRPPPQAVQP 128 S + P L++Y +S R +P S + P +PP+ SPH P Sbjct: 139 SSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPT 198 Query: 129 RPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQ 188 PS + G E L G G P L P ++P P+ P PP P PP R Sbjct: 199 VPS--SLGFERLAGG----GVLGPAGLGPAQTP---------PYRPGPPDPPPPPRHL-- 241 Query: 189 PPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPG-LAPQRGRGG 247 P + ++A A + G PG P+R Sbjct: 242 -----------------PTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPR 284 Query: 248 LLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSC 307 V+ H QRP + P PP P A + L+ C S P A +C Sbjct: 285 QDTVIKH---YQRPASAQPPPPPP--------PAHALQHYLS--CGGSYPSMGHRANLAC 331 Query: 308 PAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLGDAAG 348 PL GG P + + +SG A +AAG Sbjct: 332 S---PLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAG 369 Score = 33.9 bits (76), Expect = 0.26 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 19/84 (22%) Query: 121 PPPQAVQPRPSEPTPGSEALPPGS----LPEGEPRPYALPPRESPAPRPF---------- 166 PPP + ++PTP L G L P P LP S AP P Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823 Query: 167 -----RWGDPFSPAPPRPQPPSRP 185 R G P P PP P PP P Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMP 847 Score = 31.2 bits (69), Expect = 1.7 Identities = 28/103 (27%), Positives = 33/103 (32%), Gaps = 22/103 (21%) Query: 105 PADPAAPPSSPHAPTRP-------PPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPP 157 P PA P P+ P R P + P P + P L + P A PP Sbjct: 982 PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPP 1041 Query: 158 RESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRP 200 P PP P P S P S P F S +P Sbjct: 1042 PPPP--------------PPPPAPASEPKGGLTS-PIFCSTKP 1069 Score = 30.0 bits (66), Expect = 3.7 Identities = 31/125 (24%), Positives = 41/125 (32%), Gaps = 13/125 (10%) Query: 81 PCRRLASYSFWSSAPWRELTLPVSPADPAAP----PSSPHAPTRPPPQAVQPRPSEPTPG 136 P RR SA P +PA P P ++ P P+ P P P Sbjct: 1673 PVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732 Query: 137 SEALPPGSLPEGE-----PRPY----ALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAA 187 S P E E RP A R++ R G P + P+ +P A Sbjct: 1733 SLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAE 1792 Query: 188 QPPSR 192 PP + Sbjct: 1793 PPPKK 1797 Score = 29.6 bits (65), Expect = 4.9 Identities = 104/384 (27%), Positives = 121/384 (31%), Gaps = 99/384 (25%) Query: 48 VPS--GLRRLADP-IPGNARAGVARTEQ-RDHSQSSPPCRRLASYSFWSSAPWRELTLPV 103 VPS G RLA + G A G A+T R PP R F L Sbjct: 199 VPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQF-------NLLASS 251 Query: 104 SPADPAAPPSSPH-------APTRPPPQAVQPR---------------PSEPTPGSEALP 141 S A AA SSP AP PPP+ PR P P P + AL Sbjct: 252 SAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQ 311 Query: 142 P-----GSLPE-GEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPS---- 191 GS P G A P P P G+P P + A P Sbjct: 312 HYLSCGGSYPSMGHRANLACSPLGGGEPSPGA-GEPSKAGPSGATAGASGRATGPEAAGG 370 Query: 192 ----------RPAFRSPRPVRG-------------PHPRRAVVVAVLFGVQAPRRDVAEG 228 RP +SP G P P R+ + P A G Sbjct: 371 GGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATG 430 Query: 229 ------GLRRDGRRPG-----LAPQ---RGRGGLLLVVLHAATVQRPRLGRGPSRPPRGP 274 G PG L PQ +G GG L A P GP +PP GP Sbjct: 431 KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKA----PSYSGGPPQPPSGP 486 Query: 275 ----VGVCR---PQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAPR 327 + C+ P Q Q L V PG ++ P A P +T S PA Sbjct: 487 PPPGLATCQSYSPDQLQGQ-LYGVQGEPYPG-PAAHSQGLPTASPSLSYSTGHS--PALS 542 Query: 328 LHLGSLLPSSSGGARLGDAAGTTH 351 H G PSS GG G A +H Sbjct: 543 GHGGGWGPSSLGG---GGEASPSH 563 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 60.1 bits (144), Expect = 3e-09 Identities = 56/158 (35%), Positives = 66/158 (41%), Gaps = 25/158 (15%) Query: 58 PIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHA 117 P P A A A T++R S+ P R AS S P E PV +P Sbjct: 519 PAPAPALASAA-TKERTESEVPP---RPASPKVTRSPP--ETAAPVEDMARRTKRPAPAR 572 Query: 118 PTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPR------ESPAPRPFRWGDP 171 PT PPPQ R S P P LPPGS G P+ ALP R +P P P Sbjct: 573 PTMPPPQVSGSRSSPPAP---PLPPGSGSPGTPQ--ALPRRLVGSSLRAPTVPP-----P 622 Query: 172 FSPAPPRP---QPPSRPAAQPPSRPAFRSPRPVRGPHP 206 P PP+P Q PA+ P+ P SP PV +P Sbjct: 623 LPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNP 660 Score = 33.5 bits (75), Expect = 0.34 Identities = 35/135 (25%), Positives = 39/135 (28%), Gaps = 24/135 (17%) Query: 98 ELTLPVSPADPAAPPSSPHAPTRPPP------------QAVQPRPSEP----TPGSEALP 141 EL P P +P P P V PRP+ P +P A P Sbjct: 498 ELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAP 557 Query: 142 PGSLPEGEPRPY-ALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPP-------SRP 193 + RP A P P R P P PP P P A P P Sbjct: 558 VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAP 617 Query: 194 AFRSPRPVRGPHPRR 208 P P P P R Sbjct: 618 TVPPPLPPTPPQPAR 632 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 58.9 bits (141), Expect = 7e-09 Identities = 60/196 (30%), Positives = 76/196 (38%), Gaps = 30/196 (15%) Query: 112 PSSPHAPTRPPPQAVQPRPSE-------------PTPGSEALPPGSLPEGEPRPYALPPR 158 P+ P A RPPPQ P+P P G + L P G P P LP Sbjct: 452 PAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511 Query: 159 ESPAPRPFRWGDPFSPAPPRPQPP--SRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLF 216 S +P P + R P P A P +RP SP P R P +A + Sbjct: 512 TSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP-ASPSPQRQAGPPQATRQTSVS 570 Query: 217 GVQAPRRDVA-EGGLRRDGRRPGLAPQR--GRGGLLLVVLHAATVQRPRLGRGPSRPPR- 272 G P+ A GG +R G PQ+ G G A V PR G ++ PR Sbjct: 571 GPAPPKASGAPPGGQQRQG-----PPQKPPGPAGPTRQASQAGPV--PRTGPPTTQQPRP 623 Query: 273 ---GPVGVCRPQVAQR 285 GP G +PQ+AQ+ Sbjct: 624 SGPGPAGRPKPQLAQK 639 Score = 41.2 bits (95), Expect = 0.002 Identities = 44/157 (28%), Positives = 59/157 (37%), Gaps = 34/157 (21%) Query: 72 QRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPS 131 Q+ SQ++PP + S PV+ A P + P A P QA P+ + Sbjct: 516 QQPASQAAPPTQGQGRQS-----------RPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564 Query: 132 EPTPGSEALPP---GSLPEGEPRPYALPPRESPAPR-PFRWGDPFSPAP----PR----- 178 T S PP G+ P G+ R PP++ P P P R P P P Sbjct: 565 RQTSVSGPAPPKASGAPPGGQQRQG--PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPR 622 Query: 179 ---PQPPSRPAAQPPSRPAFRSPRPVRG-----PHPR 207 P P RP Q +P+ P P PHP+ Sbjct: 623 PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659 Score = 35.4 bits (80), Expect = 0.088 Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 8/96 (8%) Query: 108 PAAPPSSPHAPTRPPPQA-VQPRPSEPTPGSEALPPGSLPEGEPRPYAL--PPRESPAPR 164 P P P PTR QA PR PT + P G P G P+P P ++ P P Sbjct: 590 PPQKPPGPAGPTRQASQAGPVPRTGPPTT-QQPRPSGPGPAGRPKPQLAQKPSQDVPPPA 648 Query: 165 PFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRP 200 G P P + Q + P P PRP Sbjct: 649 TAAAGGPPHPQLNKSQSLTNAFNLPEPAP----PRP 680 Score = 35.0 bits (79), Expect = 0.12 Identities = 43/160 (26%), Positives = 51/160 (31%), Gaps = 33/160 (20%) Query: 39 PLAAGGRCRVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAP--- 95 P+A G P R A P P T Q S +PP S AP Sbjct: 535 PVAGGPGA--PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKA--------SGAPPGG 584 Query: 96 WRELTLPVSPADPAAPPSSPH----APTRPPPQAVQPRPSEP------------TPGSEA 139 + P P PA P P PP QPRPS P P + Sbjct: 585 QQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDV 644 Query: 140 LPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRP 179 PP + G P P+ + F +P APPRP Sbjct: 645 PPPATAAAGGP-PHPQLNKSQSLTNAFNLPEP---APPRP 680 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 58.9 bits (141), Expect = 7e-09 Identities = 60/196 (30%), Positives = 76/196 (38%), Gaps = 30/196 (15%) Query: 112 PSSPHAPTRPPPQAVQPRPSE-------------PTPGSEALPPGSLPEGEPRPYALPPR 158 P+ P A RPPPQ P+P P G + L P G P P LP Sbjct: 452 PAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511 Query: 159 ESPAPRPFRWGDPFSPAPPRPQPP--SRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLF 216 S +P P + R P P A P +RP SP P R P +A + Sbjct: 512 TSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP-ASPSPQRQAGPPQATRQTSVS 570 Query: 217 GVQAPRRDVA-EGGLRRDGRRPGLAPQR--GRGGLLLVVLHAATVQRPRLGRGPSRPPR- 272 G P+ A GG +R G PQ+ G G A V PR G ++ PR Sbjct: 571 GPAPPKASGAPPGGQQRQG-----PPQKPPGPAGPTRQASQAGPV--PRTGPPTTQQPRP 623 Query: 273 ---GPVGVCRPQVAQR 285 GP G +PQ+AQ+ Sbjct: 624 SGPGPAGRPKPQLAQK 639 Score = 41.2 bits (95), Expect = 0.002 Identities = 44/157 (28%), Positives = 59/157 (37%), Gaps = 34/157 (21%) Query: 72 QRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPS 131 Q+ SQ++PP + S PV+ A P + P A P QA P+ + Sbjct: 516 QQPASQAAPPTQGQGRQS-----------RPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564 Query: 132 EPTPGSEALPP---GSLPEGEPRPYALPPRESPAPR-PFRWGDPFSPAP----PR----- 178 T S PP G+ P G+ R PP++ P P P R P P P Sbjct: 565 RQTSVSGPAPPKASGAPPGGQQRQG--PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPR 622 Query: 179 ---PQPPSRPAAQPPSRPAFRSPRPVRG-----PHPR 207 P P RP Q +P+ P P PHP+ Sbjct: 623 PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659 Score = 38.5 bits (88), Expect = 0.010 Identities = 31/86 (36%), Positives = 36/86 (41%), Gaps = 10/86 (11%) Query: 108 PAAPPSSPHAPTRPPPQA-VQPRPSEPTPGSEALPPGSLPEGEPRPYAL--PPRESPAPR 164 P P P PTR QA PR PT + P G P G P+P P ++ P P Sbjct: 590 PPQKPPGPAGPTRQASQAGPVPRTGPPTT-QQPRPSGPGPAGRPKPQLAQKPSQDVPPPA 648 Query: 165 PFRWGDPFSPAPPRPQPPSRPA-AQP 189 G PP PQ + PA AQP Sbjct: 649 TAAAG-----GPPHPQLKASPAQAQP 669 Score = 38.1 bits (87), Expect = 0.014 Identities = 40/126 (31%), Positives = 47/126 (37%), Gaps = 22/126 (17%) Query: 106 ADPAAPPSSPHAPTRP--PPQAV-QPRPSEPTP--GSEALPPGSLPEGEPRPYALP---- 156 A PAA P + +P R PPQA Q S P P S A P G +G P+ P Sbjct: 542 APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT 601 Query: 157 ---------PRESPA----PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRG 203 PR P PRP G P P Q PS+ P + A P P Sbjct: 602 RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLK 661 Query: 204 PHPRRA 209 P +A Sbjct: 662 ASPAQA 667 >gi|236459851 ubinuclein 2 [Homo sapiens] Length = 1347 Score = 58.2 bits (139), Expect = 1e-08 Identities = 49/124 (39%), Positives = 54/124 (43%), Gaps = 23/124 (18%) Query: 79 SPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSE 138 SP RR A Y P RE P P PP P R P +A P P EP P S+ Sbjct: 13 SPVRRREAEYP----GPERE------PEYPREPPRLEPQPYREPARAEPPAPREPAPRSD 62 Query: 139 ALPPG---SLPEGEPRPYALPP----RESPAPRPFRWGDPFSPAPPRPQPPSRPA--AQP 189 A PP LP+ E A PP RE P P P PF P P +P PP A A+ Sbjct: 63 AQPPSREKPLPQREV-SRAEPPMSLQREPPRPEP---PPPFPPLPLQPPPPRESASRAEQ 118 Query: 190 PSRP 193 P RP Sbjct: 119 PPRP 122 Score = 38.9 bits (89), Expect = 0.008 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 9/90 (10%) Query: 73 RDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSS-PHAPTRP-PPQAVQPRP 130 R+ +++ PP R + + P RE LP A PP S P RP PP P P Sbjct: 44 REPARAEPPAPREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQREPPRPEPPPPFPPLP 103 Query: 131 SEPTPGSEALPPGSLPEGEPRPYALPPRES 160 +P P E+ S E PR PPRE+ Sbjct: 104 LQPPPPRES---ASRAEQPPR----PPRET 126 Score = 30.0 bits (66), Expect = 3.7 Identities = 34/133 (25%), Positives = 49/133 (36%), Gaps = 8/133 (6%) Query: 55 LADPIPGNARAG----VARTEQRDHSQSSPPCRRLASYSFWSS--APWRELTLPVSPADP 108 L+ P PGN G V+RT + S+ + + S +P+ P A P Sbjct: 984 LSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASP 1043 Query: 109 AAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRW 168 P +SP P P A P+PS S + S P+P P SP + Sbjct: 1044 K-PATSPKPLPSPKPSA-SPKPSLSAKPSVSTKLISKSNPTPKPTVSPSSSSPNALVAQG 1101 Query: 169 GDPFSPAPPRPQP 181 + +P QP Sbjct: 1102 SHSSTNSPVHKQP 1114 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 58.2 bits (139), Expect = 1e-08 Identities = 95/347 (27%), Positives = 121/347 (34%), Gaps = 76/347 (21%) Query: 49 PSGL--RRLADPIPGNARAG---VARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPV 103 P GL RLADP+P + + R + PP L + S+ A R +P Sbjct: 181 PGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240 Query: 104 SPADPAAPPSSPHAPTRPP----PQAVQPRPSEPT------PGSEALPPGS-----LPEG 148 P AP +S P+ PP A+ P P P+ PG + PP S LP Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300 Query: 149 EPRPYALPPRESPAPRPFRWGDPFSPA-----PPRPQPPS----RPAAQPPS-------R 192 P E P PF S A PP P P + RP AQ PS R Sbjct: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360 Query: 193 PAFRSPR---------PVRGP------HPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRP 237 P+ R PR RGP PR V F + P + + L G P Sbjct: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLG-LP 419 Query: 238 GLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLP 297 P G L+ A P L G PR P+ +P SLP Sbjct: 420 TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI---QP--------------SLP 462 Query: 298 GNRRLATRSCPAAFPLQGGATLPSSLPAPRLHLGSLLPSSSGGARLG 344 G + S P A P A+ +P+P +L S S G +G Sbjct: 463 GTTSGSLSSVPGA-PAPPAASKAPVVPSP------VLQSPSEGLGMG 502 Score = 38.1 bits (87), Expect = 0.014 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 103 VSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEG--EPR-PYALPPRE 159 VSP P+A P PT P P EP S+A P + P G PR +P Sbjct: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGG 197 Query: 160 SPAPRPFRWGDPFSPAPPRP 179 S +PR G+ SPAPP P Sbjct: 198 SSSPRFLPRGNAPSPAPPPP 217 Score = 33.5 bits (75), Expect = 0.34 Identities = 54/180 (30%), Positives = 69/180 (38%), Gaps = 23/180 (12%) Query: 55 LADPIPGNARAGVARTEQRDHSQSSPPCRR-LASYSFWSSAPWRELTLPVSPADPAAPPS 113 LA PG A GV + D ++ R+ +A + + S E T S A P Sbjct: 79 LAPVTPGGA--GVGPASEEDMTKLCNHRRKAVAMATLYRSM---ETTCSHSSPGEGASPQ 133 Query: 114 SPHAPTRPPPQAVQP---RPSEPTPGSEALPPGSLPEGEPR-PYALPPRESPAPR-PFRW 168 H + PP A P P+ P G PGSLP P A P P P R Sbjct: 134 MFHTVSPGPPSARPPCRVPPTTPLNGG----PGSLPPEPPSVSQAFPTLAGPGGLFPPRL 189 Query: 169 GDPF----SPAP---PRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAP 221 DP S +P PR PS PA PP + +P G R ++V + L AP Sbjct: 190 ADPVPSGGSSSPRFLPRGNAPS-PAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAP 248 Score = 33.1 bits (74), Expect = 0.44 Identities = 52/208 (25%), Positives = 67/208 (32%), Gaps = 38/208 (18%) Query: 39 PLAAGGRCRVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRE 98 PLA G PS + LA + G G+ S PP L ++S + Sbjct: 511 PLAGGEAFPFPSPEQGLA--LSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGG 568 Query: 99 LTLPVSPA-DPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALP- 156 P P P P P AP P ++ P P S+ LPP S P LP Sbjct: 569 GQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPL 628 Query: 157 ---------------PRESPAPRPFRWGDPFSPA--PPRPQPPS--------------RP 185 P+ PF SP PP PP+ P Sbjct: 629 LALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPP 688 Query: 186 AAQPPSRPAFRSPRPVRGPHPRRAVVVA 213 + PP +P+P GP P +V A Sbjct: 689 SGTPPQPCVLSAPQP--GP-PTSSVTTA 713 Score = 32.0 bits (71), Expect = 0.98 Identities = 34/126 (26%), Positives = 41/126 (32%), Gaps = 28/126 (22%) Query: 94 APWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPY 153 +P L + PA P P + A P P+ PG P L G+P P Sbjct: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553 Query: 154 AL---------------PPRESPAPRPFRWGDPFSPAPPR----------PQPPS---RP 185 L PP E P P G P +P P P PPS P Sbjct: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPP 613 Query: 186 AAQPPS 191 + PPS Sbjct: 614 PSAPPS 619 Score = 32.0 bits (71), Expect = 0.98 Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 5/53 (9%) Query: 111 PPSSPHAPTRPPPQ---AVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRES 160 PP P AP PP A++P P+ P P S PP P+ P P L R S Sbjct: 804 PPEQPEAPCLPPESPASALEPEPARP-PLSALAPPHGSPD-PPVPELLTGRGS 854 Score = 30.4 bits (67), Expect = 2.8 Identities = 53/203 (26%), Positives = 65/203 (32%), Gaps = 31/203 (15%) Query: 101 LPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRES 160 LP P + P P P +P PG+ A P S P P P E Sbjct: 439 LPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498 Query: 161 ---------PAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPV---RGPHPRR 208 P P P G+ F P P P A P P+ G P Sbjct: 499 LGMGAGPACPLP-PLAGGEAF----PFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553 Query: 209 AVVVAVLFGV------QAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRP- 261 ++ LFGV Q P + G P LAP G LLV A+ + P Sbjct: 554 PLLNHSLFGVLTGGGGQPPPEPLLP---PPGGPGPPLAPGEPEGPSLLV---ASLLPPPP 607 Query: 262 -RLGRGPSRPPRGPVGVCRPQVA 283 L PS PP + P +A Sbjct: 608 SDLLPPPSAPPSNLLASFLPLLA 630 Score = 30.0 bits (66), Expect = 3.7 Identities = 15/39 (38%), Positives = 17/39 (43%), Gaps = 5/39 (12%) Query: 102 PVSPADPAAPPSSPHA-----PTRPPPQAVQPRPSEPTP 135 P P P PP SP + P RPP A+ P P P Sbjct: 805 PEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDP 843 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/123 (36%), Positives = 55/123 (44%), Gaps = 16/123 (13%) Query: 99 LTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPR 158 ++ P PA PAA +P PT P A P P EPT + A+PP PE P A P Sbjct: 994 VSTPEEPASPAAAVPTPEEPT--SPAAAVPTPEEPTSPAAAVPP---PEEPTSPAAAVPT 1048 Query: 159 ----ESPAPRPFRWGDPFSPAP--PRPQPPSRPAA-----QPPSRPAFRSPRPVRGPHPR 207 SPA +P SPA P P+ P+ PAA + P+ PA P P P Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108 Query: 208 RAV 210 AV Sbjct: 1109 AAV 1111 Score = 53.1 bits (126), Expect = 4e-07 Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 20/131 (15%) Query: 93 SAPWRELTLPVSPADPAAP------PSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLP 146 ++P + P P PAA P+SP A PP + P + PTP P ++P Sbjct: 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP 1060 Query: 147 EGEPRPYALPPRESPAPRPFRWGDPFSPAP--PRPQPPSRPAA-----QPPSRPAFRSPR 199 P P P P +P SPA P P+ P+ PAA + P+ PA P Sbjct: 1061 --TPEEPTSPAAAVPTPE-----EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1113 Query: 200 PVRGPHPRRAV 210 P P AV Sbjct: 1114 PEEPASPAAAV 1124 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/146 (28%), Positives = 53/146 (36%), Gaps = 22/146 (15%) Query: 93 SAPWRELTLPVSPADPAAP------PSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLP 146 ++P + P P PAA P+SP A P + P + PTP A P ++P Sbjct: 1066 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVP 1125 Query: 147 EGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSR-------PAAQPPSRPAFRSPR 199 P A P P P +P PAP P P P + + PA P Sbjct: 1126 --TPEEPASPAAAVPTPE-----EPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT 1178 Query: 200 PVRGPHPRRAVVVAVLFGVQAPRRDV 225 P A VVA L +P V Sbjct: 1179 PAES--ASFAAVVATLEEPTSPAASV 1202 Score = 42.7 bits (99), Expect = 6e-04 Identities = 41/152 (26%), Positives = 56/152 (36%), Gaps = 27/152 (17%) Query: 93 SAPWRELTLPVSPADPAAP------PSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLP 146 ++P + P P PAA P+SP A P + P + PTP A P ++P Sbjct: 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138 Query: 147 EGE----PRPYALPPRESPA-----PRPFRWGDPFSPAPPRPQPPSRPAA----QPPSRP 193 E P P P ES + P P P + P + S A + P+ P Sbjct: 1139 TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198 Query: 194 AFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDV 225 A P P A +VA L +P V Sbjct: 1199 AASVPTP--------AAMVATLEEFTSPAASV 1222 Score = 36.6 bits (83), Expect = 0.040 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 60 PGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPT 119 P + A V+ E+ ++ P + S + EL+ P + P+SP A Sbjct: 1228 PASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAV 1287 Query: 120 RPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPY---ALPPRESPAP 163 + P + PTP A+P S+P E A+PP E +P Sbjct: 1288 SNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334 Score = 30.8 bits (68), Expect = 2.2 Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 8/123 (6%) Query: 92 SSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPR 151 S++P + P A AA ++ PT P P T P S+P E Sbjct: 1169 SASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSE-E 1227 Query: 152 PYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAA----QPPSRPAFRSPRPVRGPHPR 207 P +L S P P + P +P S AA + S PA P P P Sbjct: 1228 PASLAAAVSNPEEP---TSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPA 1284 Query: 208 RAV 210 AV Sbjct: 1285 AAV 1287 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 57.4 bits (137), Expect = 2e-08 Identities = 41/124 (33%), Positives = 43/124 (34%), Gaps = 27/124 (21%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRP--SEPTPGSEALPP-------------GSLPEGE 149 P P PP P P PPP V P P P G PP G LP G Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296 Query: 150 PRPYA--------LPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPV 201 P P PP++ P P P PF P PP P P A PP P P Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPPP----GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 Query: 202 RGPH 205 PH Sbjct: 353 PAPH 356 Score = 53.5 bits (127), Expect = 3e-07 Identities = 40/106 (37%), Positives = 42/106 (39%), Gaps = 11/106 (10%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGE--PRPYALPPRESPA 162 PA P PP P P P PRP PG PPG P G+ P P A PP Sbjct: 220 PAGPGGPP--PPFPAGQTP----PRPPLGPPGPPG-PPGPPPPGQVLPPPLAGPPNRGDR 272 Query: 163 PRP--FRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 P P G PF P P PP P P P P P +GP P Sbjct: 273 PPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP 318 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/107 (34%), Positives = 40/107 (37%), Gaps = 16/107 (14%) Query: 102 PVSPADPAAPPSSPH--APTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRE 159 P+ P P PP P P PPP P P PPG P P P L P Sbjct: 288 PLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP----------PPGPFPPRPPGP--LGPPL 335 Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 + AP P G P P P P P PA PP + RGP P Sbjct: 336 TLAPPPHLPGPP--PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380 Score = 43.5 bits (101), Expect = 3e-04 Identities = 35/99 (35%), Positives = 40/99 (40%), Gaps = 11/99 (11%) Query: 101 LPVSPADPA---APPSSPHAPTR---PPPQAVQPRPSEPT-PGSEALPPGSLPEGEPRPY 153 LP P P PP P P + PPP PRP P P PP LP P Sbjct: 292 LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAP 351 Query: 154 ALPPRESPA--PRPFRWGDPFSPAPPRPQPPSRPAAQPP 190 P +PA P P G P S + R PP+ P +PP Sbjct: 352 PPAPHVNPAFFPPPTNSGMPTSDS--RGPPPTDPYGRPP 388 Score = 37.7 bits (86), Expect = 0.018 Identities = 33/100 (33%), Positives = 38/100 (38%), Gaps = 9/100 (9%) Query: 109 AAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYAL---PPRESPAPRP 165 A PP P + R PG + P + P G P P+ PPR P Sbjct: 186 AGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPP- 244 Query: 166 FRWGDPFSPAPPRP-QPPSRPAAQPPSRPAFRSPRPVRGP 204 G P P PP P Q P A PP+R R P PV P Sbjct: 245 ---GPPGPPGPPPPGQVLPPPLAGPPNR-GDRPPPPVLFP 280 Score = 31.6 bits (70), Expect = 1.3 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 99 LTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEAL-PPGSLPEGEPRPY 153 LTL P P PP +P P P + P S++ PP + P G P PY Sbjct: 335 LTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPY 390 >gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 57.4 bits (137), Expect = 2e-08 Identities = 62/182 (34%), Positives = 73/182 (40%), Gaps = 41/182 (22%) Query: 106 ADPAAPPSSPHAPTRPPPQAVQPRPSEPTPG-------SEALPPGSLPEGEPRPYALPPR 158 A P AP P A A QPR P P + LPP P G P A+P Sbjct: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP---AVPAA 111 Query: 159 ESPAPRPFRWGDPFSPAPPRPQPPSRP--AAQPPSRPAFRSPR-PVRGPHPRRAVVVAVL 215 SP P P R P SP PPRP PS P PPS A +PR P+ P P+ +V Sbjct: 112 PSPGPLPAR---PSSP-PPRPSLPSGPHRPVLPPS--ALAAPRPPLARPLPQGSVT---- 161 Query: 216 FGVQAPRRDVAEGGLRRDGRRPGLAPQRGR--------------GGLLLVVLHAATVQRP 261 A ++ RR G L P R GLLL++L AA V+ P Sbjct: 162 ----AREQEQRPRSRRRAGAPEALGPALTRIHNVEGSKDSWNCGQGLLLLMLSAAPVRTP 217 Query: 262 RL 263 L Sbjct: 218 GL 219 Score = 36.6 bits (83), Expect = 0.040 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 4/62 (6%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESP 161 P SP + PS PH P PP PRP P + LP GS+ E R + Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRP----PLARPLPQGSVTAREQEQRPRSRRRAG 176 Query: 162 AP 163 AP Sbjct: 177 AP 178 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 57.0 bits (136), Expect = 3e-08 Identities = 60/206 (29%), Positives = 69/206 (33%), Gaps = 56/206 (27%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGS----------EALPPGSL------ 145 P P PP+ P P PP A PS TPG+ PPG + Sbjct: 249 PPGALPPGIPPAMP-PPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMS 307 Query: 146 --------PEGEPRPYALPPRE--SPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAF 195 P G P+A PP P PRP P P P PP P PP P F Sbjct: 308 QMQLAHHGPHGLGHPHAGPPGSGGQPPPRP-------PPGMPHPGPP--PMGMPPRGPPF 358 Query: 196 RSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHA 255 SP GP P G++ P + G R P QRG Sbjct: 359 GSPMGHPGPMPPH--------GMRGPPPLMPPHGYTGPPRPPPYGYQRG----------- 399 Query: 256 ATVQRPRLGRGPSRPPRGPVGVCRPQ 281 + PR P PPRGP+ PQ Sbjct: 400 -PLPPPRPTPRPPVPPRGPLRGPLPQ 424 Score = 49.7 bits (117), Expect = 5e-06 Identities = 39/111 (35%), Positives = 41/111 (36%), Gaps = 22/111 (19%) Query: 104 SPADPAAPPSSPHAPTRPPPQAVQPRPSE-----PTPGSEALPPGSLPEGEPRPYALPPR 158 +P A P A PPP A P S P PG PPGS P P P ALPP Sbjct: 199 NPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMP--PPGSFPPPVPPPGALPPG 256 Query: 159 ESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRG---PHP 206 PA PP P PP PPS + P G PHP Sbjct: 257 IPPA------------MPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHP 295 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 56.6 bits (135), Expect = 4e-08 Identities = 36/109 (33%), Positives = 43/109 (39%), Gaps = 6/109 (5%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEG--EPRPYALPPRE 159 P P PP P P PPPQ P PG PP P+G + R PP + Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---PQGGSKSRSARSPPGK 365 Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRR 208 P +P P PP P +P A P +P PRP +G P R Sbjct: 366 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ-GPPRPPQGGRPSR 413 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 14/111 (12%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPP---GSLPEGEP---RPYALPPR 158 P P +PP P P PP QP+ P PG PP G+ P+G P +P PP+ Sbjct: 47 PQGPPSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 104 Query: 159 --ESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPR 207 +S +PR P P P PQ ++P PP + P P G P+ Sbjct: 105 GDKSRSPR----SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151 Score = 53.5 bits (127), Expect = 3e-07 Identities = 60/223 (26%), Positives = 79/223 (35%), Gaps = 30/223 (13%) Query: 58 PIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHA 117 P PG + + + + S SPP + P P P PP P Sbjct: 216 PPPGKPQGPPPQGDNKSQSARSPPGKP-------QGPP------PQGGNQPQGPPPPPGK 262 Query: 118 PTRPPPQAVQPRPSEPTPGSEALPPGSLPEG--EPRPYALPPRESPAPRPFRWGDPFSPA 175 P PPPQ P PG PP P+G + R PP + P P P P Sbjct: 263 PQGPPPQGGNKPQGPPPPGKPQGPP---PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319 Query: 176 PP--RPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRD 233 PP +PQ P P P P +GP P+ + ++P +G +++ Sbjct: 320 PPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQGG---SKSRSARSPPGK-PQGPPQQE 373 Query: 234 GRRP-GLAPQRGRGGLLLVVLHAATVQ---RPRLGRGPSRPPR 272 G P G P G A Q RP G PSRPP+ Sbjct: 374 GNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416 Score = 52.4 bits (124), Expect = 7e-07 Identities = 66/250 (26%), Positives = 85/250 (34%), Gaps = 49/250 (19%) Query: 49 PSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADP 108 P G + P P G + S SPP + + P P P P Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---PPPPGKP 139 Query: 109 AAPPSS----------PHAPTRPPPQA-VQPRPSEPTPGSEALPP---GSLPEGEPRPYA 154 PP P P PPPQ + R S PG PP G+ P+G P Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP--- 196 Query: 155 LPPRESPAPRPFRWGDPFSPAPP-RPQPP-------SRPAAQPPSRPAFRSPRPVRGPHP 206 PP + P P P P PP +PQ P S+ A PP +P + P P G P Sbjct: 197 -PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP--QGPPPQGGNQP 253 Query: 207 RRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQ--RGRGGLLLVVLHAATVQRPRLG 264 + P+ +GG + G P PQ +GG + R Sbjct: 254 QGPPPPP-----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG-----------SKSRSS 297 Query: 265 RGPSRPPRGP 274 R P P+GP Sbjct: 298 RSPPGKPQGP 307 Score = 52.0 bits (123), Expect = 9e-07 Identities = 61/239 (25%), Positives = 84/239 (35%), Gaps = 45/239 (18%) Query: 58 PIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSS--- 114 P PG + + + + S SPP + + P P P P PP Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP---PPPPGKPQGPPPQGGN 210 Query: 115 -------PHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEG--EPRPYALPPRESPAPRP 165 P P PPPQ S +P + P G P+G +P+ PP + P P Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPPP 268 Query: 166 FRWGDPFSPAPP-RPQPP-------SRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFG 217 P P PP +PQ P SR + PP +P + P P G P+ Sbjct: 269 QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP--QGPPPQGGNQPQGPPPPP---- 322 Query: 218 VQAPRRDVAEGGLRRDGRRPGLAPQ--RGRGGLLLVVLHAATVQRPRLGRGPSRPPRGP 274 P+ +GG + G P PQ +GG + R R P P+GP Sbjct: 323 -GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG-----------SKSRSARSPPGKPQGP 369 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/136 (27%), Positives = 49/136 (36%), Gaps = 30/136 (22%) Query: 102 PVSPADPAAPP-SSPHAPTRPPPQAVQPRPSEPTPGS--EALPPGSLPEGEP------RP 152 P P P PP + P PPP +P+ P G+ + PP P+G P R Sbjct: 51 PSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 110 Query: 153 YALPPRESPAPRPFRWGDPFSPAPP----------------RPQPPSRPAAQPP-----S 191 PP + P P P P PP P PP +P PP S Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 170 Query: 192 RPAFRSPRPVRGPHPR 207 R + P +GP P+ Sbjct: 171 RSSRSPPGKPQGPPPQ 186 Score = 37.4 bits (85), Expect = 0.023 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 24/99 (24%) Query: 130 PSEPTPGSEALPP--GSLPEGEP----RPYALPPR-----ESPAPRPFRWGDPFSP---- 174 PS + PP G+ P+G P +P PP+ + P P P G P P Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQG 85 Query: 175 --APPRPQPPSRPAAQPPSRPAFRSPR----PVRGPHPR 207 P P PP +P PP RSPR +GP P+ Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 124 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 56.6 bits (135), Expect = 4e-08 Identities = 41/115 (35%), Positives = 45/115 (39%), Gaps = 15/115 (13%) Query: 101 LPVSPADPAAPPSSPHA-PTRPPPQAVQPRPSE--------PTPGSEALPPGSLPEGEPR 151 LP + PA P PH P PPP V P P+ PTPG PP P P Sbjct: 461 LPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520 Query: 152 PYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 P LPP + P P P PP PP PA P +P P P G P Sbjct: 521 PPRLPPTHAVPPHP----PPGLGLPPASYPP--PAVPPGGQPPVPPPIPPPGMPP 569 Score = 50.4 bits (119), Expect = 3e-06 Identities = 40/121 (33%), Positives = 50/121 (41%), Gaps = 11/121 (9%) Query: 95 PWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPT-----PGSEALPPGSLPEGE 149 P ++ P PA PP PH P PPP + S + G ++L EG Sbjct: 397 PKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEG- 455 Query: 150 PRPYALPPRES-PAPRPF--RWGDPFSPAPPRPQPPSR--PAAQPPSRPAFRSPRPVRGP 204 P ALPP PA P+ P P PP P PP+ P A PP P + P P P Sbjct: 456 PSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP 515 Query: 205 H 205 + Sbjct: 516 N 516 Score = 42.4 bits (98), Expect = 7e-04 Identities = 46/157 (29%), Positives = 58/157 (36%), Gaps = 40/157 (25%) Query: 67 VARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAV 126 V + +Q SQSS P S P ++ P PA P +P PQ Sbjct: 285 VPQVQQSQPSQSSEP-----------SQPQQK-----DPQQPAQQQQPAQQPKKPSPQPS 328 Query: 127 QPR---------PSEPTPGSEALPPGSLPEGE----PRPYALPPRESPAPRPFRWGDPFS 173 PR P E +E PP +P+ E P P A PP + P G+ Sbjct: 329 SPRQVKRAVVVSPKEENKAAEP-PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEP 387 Query: 174 PAP------PRPQ--PPSRPAA--QPPSRPAFRSPRP 200 P P P+ Q PP+ PA QPP P P P Sbjct: 388 PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPP 424 Score = 38.1 bits (87), Expect = 0.014 Identities = 34/113 (30%), Positives = 45/113 (39%), Gaps = 21/113 (18%) Query: 111 PPSSPHAPTRPP-----PQAVQPRPSEPTPGSEALPP----GSLPEGEPRPYALPPRESP 161 P +PH +PP PQ Q + S+P+ SE P P + +P P + SP Sbjct: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP 325 Query: 162 ---APRPFRWGDPFSP-------APPRPQPPSRPAAQPPSRPAFRSPRPVRGP 204 +PR + SP PP P+ P PP PA P P R P Sbjct: 326 QPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA--HPPPDRKP 376 Score = 37.0 bits (84), Expect = 0.030 Identities = 34/101 (33%), Positives = 40/101 (39%), Gaps = 25/101 (24%) Query: 103 VSPADP--AAPPSSPHAP----TRPPPQAVQPRPSEPTPGSEAL----PPGSLPEGEPRP 152 VSP + AA P P P T PP P P P + AL PPG + + Sbjct: 339 VSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPK 398 Query: 153 YALPPRESPAP--RPFRWGDPFSPAPPRPQPPSRPAAQPPS 191 +PP PAP +P P P RP PP PPS Sbjct: 399 VQIPPPAHPAPVHQP-------PPLPHRPPPP------PPS 426 Score = 33.1 bits (74), Expect = 0.44 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 7/76 (9%) Query: 145 LPEGEPRPYALPPRESPAPR-----PFRWGDPFSPAPPRPQPPSRPA--AQPPSRPAFRS 197 +P P PP P P+ + P+ P+ + P +PA QP +P S Sbjct: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPS 324 Query: 198 PRPVRGPHPRRAVVVA 213 P+P +RAVVV+ Sbjct: 325 PQPSSPRQVKRAVVVS 340 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 56.6 bits (135), Expect = 4e-08 Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 15/109 (13%) Query: 111 PPSSPHAPTRPPPQ-AVQPRPSEPTPGSEALPP---GSLPEGEP----RPYALPPRESPA 162 PP P P PPPQ Q + P PG PP G+ P+G P +P PP+E Sbjct: 197 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNK 256 Query: 163 P-RPFRWGDPFSPAPP--RPQPPSRPAAQPPSRPAFRSPRPVRGPHPRR 208 P RP G P P PP PQ P P A P P P P +G P R Sbjct: 257 PQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGP----PPPPQGGRPHR 301 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 5/92 (5%) Query: 102 PVSPADPAAPPSSP-HAPTRPPPQAVQPRPSEPTPGSEAL--PPGSLPEGEPRPYALPPR 158 P P P PPS + P PPP +P+ P G++ PP P+G P P P + Sbjct: 219 PPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQ 278 Query: 159 ESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPP 190 P P G P P RP P P QPP Sbjct: 279 PLPPPAGKPQGPPPPPQGGRPHRP--PQGQPP 308 Score = 48.9 bits (115), Expect = 8e-06 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 13/111 (11%) Query: 111 PPSSPHAPTRPPPQAV-QPRPSEPTPGSEALPP---GSLPEGEP----RPYALPPR---- 158 PP P P PPPQ Q + P PG PP G+ +G P +P PP+ Sbjct: 155 PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214 Query: 159 -ESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRR 208 + P PRP + P S +PQ P +P P +P R P P R Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR 265 Score = 45.8 bits (107), Expect = 7e-05 Identities = 45/151 (29%), Positives = 56/151 (37%), Gaps = 26/151 (17%) Query: 111 PPSSPHAPTRPPPQAV-QPRPSEPTPGSEALPPGSLPEGEPRPYALPPR----ESPAPRP 165 PP P P PPPQ Q + P PG P G P+G + PPR E P P+ Sbjct: 71 PPPRPGKPEGPPPQGGNQSQGPPPRPGK---PEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127 Query: 166 FRW--GDPFSPAPPRPQPP--SRPAAQPPSRPAFRSPRPVRG--------PHPRRAVVVA 213 G P P P PP + PP RP P +G PHP + Sbjct: 128 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPE--- 184 Query: 214 VLFGVQAPRRDVAEGGLRRDGRRPGLAPQRG 244 G + ++G R G+ G PQ G Sbjct: 185 ---GPPPQGGNQSQGPPPRPGKPEGPPPQGG 212 Score = 45.8 bits (107), Expect = 7e-05 Identities = 57/210 (27%), Positives = 75/210 (35%), Gaps = 44/210 (20%) Query: 102 PVSPADPAAPPSSPHAPTR-PPPQAVQPRPSEPTPGSEA--------LPPGSLPEGEPRP 152 P P P PP ++ PPP+ +P P G+++ P G P+G + Sbjct: 72 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 131 Query: 153 YALPPRE-SPAPRPFRWGDPFSPAPPRPQPPSRPAAQ-------PPSRPAFRSPRPVRG- 203 PPR P P + G+ PPRP P P Q PP P P +G Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG 191 Query: 204 -------PHPRRAVVVAVLFGVQA----PRRDVAEGGLRRDGRRP-GLAPQRGRGGLLLV 251 P P + G Q+ PR EG + G +P G P G+ Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGK------ 245 Query: 252 VLHAATVQRPRLGRGPSRPPRGPVGVCRPQ 281 P+ G P RPP P G RPQ Sbjct: 246 ----PQGPPPQEGNKPQRPP--PPG--RPQ 267 Score = 45.1 bits (105), Expect = 1e-04 Identities = 43/173 (24%), Positives = 65/173 (37%), Gaps = 34/173 (19%) Query: 112 PSSPHAPTRPPPQAVQPRPSEPTPGSEA--------LPPGSLPEGEPRPYALPPRE-SPA 162 P + P R PP +P P G+++ P G P+G + PPR P Sbjct: 41 PQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 100 Query: 163 PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVR--GPHPRRAVVVAVLFGVQA 220 +P + G+ PPRP P P Q ++ PRP + GP P+ Sbjct: 101 GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG----------- 149 Query: 221 PRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRG 273 + ++G R G+ G PQ G + + P G+ PP+G Sbjct: 150 ---NQSQGPPPRPGKPEGPPPQGG---------NQSQGPPPHPGKPEGPPPQG 190 Score = 41.6 bits (96), Expect = 0.001 Identities = 41/147 (27%), Positives = 55/147 (37%), Gaps = 27/147 (18%) Query: 141 PPGSLPEGEPRPYALPPRES-PAPRPFRWGDPFSPAPPRPQPPSRPAAQ-------PPSR 192 P G P+G +P PP P RP + G+ PPRP P P Q PP R Sbjct: 36 PEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 95 Query: 193 PAFRSPRP------VRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRG 246 P +P +GP PR G + ++G R G+ G PQ G Sbjct: 96 PGKPEGQPPQGGNQSQGPPPRPGKPE----GPPPQGGNQSQGPPPRPGKPEGPPPQGG-- 149 Query: 247 GLLLVVLHAATVQRPRLGRGPSRPPRG 273 + + PR G+ PP+G Sbjct: 150 -------NQSQGPPPRPGKPEGPPPQG 169 Score = 40.0 bits (92), Expect = 0.004 Identities = 48/186 (25%), Positives = 60/186 (32%), Gaps = 38/186 (20%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPP---GSLPEGEPRPYALPPRESP 161 P PP P RPP Q + P PG PP G+ +G P P + P Sbjct: 47 PQRTPPPPGKPEG--RPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPP 104 Query: 162 APRPFRWGDPFSPAPPRPQPP--SRPAAQPPSRPAFRSPRP------VRGPHPRRAVVVA 213 G P P P PP + PP RP P +GP PR Sbjct: 105 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG---- 160 Query: 214 VLFGVQAPRRDVAEGGLRRDGRRP------GLAPQRGRGGLLLVVLHAATVQRPRLGRGP 267 P +GG + G P G PQ G + + PR G+ Sbjct: 161 ------KPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG---------NQSQGPPPRPGKPE 205 Query: 268 SRPPRG 273 PP+G Sbjct: 206 GPPPQG 211 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 56.6 bits (135), Expect = 4e-08 Identities = 39/104 (37%), Positives = 44/104 (42%), Gaps = 14/104 (13%) Query: 109 AAPPSSPHAPTRPPPQAVQPRPSEPT--PGSEA-LPPGSLPEGEP--RPYALPPRESPAP 163 + PPS AP P P + P P+ P PG LPPG P P RP +P P P Sbjct: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP 455 Query: 164 RPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPR 207 R P PP +PP P PP P PR GP PR Sbjct: 456 RLL------PPGPPPGRPPGPPPGPPPGLPPGPPPR---GPPPR 490 Score = 49.7 bits (117), Expect = 5e-06 Identities = 45/149 (30%), Positives = 49/149 (32%), Gaps = 24/149 (16%) Query: 70 TEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPR 129 T Q +PP S P ++ P P P P P AP PP Sbjct: 383 TSTASSQQQAPP----------QSVPPSQIQAPPMPGPPPLGP--PPAPPLRPPGPPTGL 430 Query: 130 PSEPTPGSEAL--PPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQ------- 180 P P PG+ PPG P P LPP P P P PP P Sbjct: 431 PPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPR 490 Query: 181 -PPSRPAAQPPSRPAFRSPR--PVRGPHP 206 PP P PP RP P P GP P Sbjct: 491 LPPPAPPGIPPPRPGMMRPPLVPPLGPAP 519 Score = 40.8 bits (94), Expect = 0.002 Identities = 45/165 (27%), Positives = 53/165 (32%), Gaps = 64/165 (38%) Query: 113 SSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPF 172 S+ + + PPQ+V P + P PG P G P PAP P R P Sbjct: 384 STASSQQQAPPQSVPPSQIQAPP-----MPGPPPLGPP----------PAP-PLRPPGPP 427 Query: 173 SPAPPRPQPPSRPAAQPPSRPAFRSPRP---VRGPHPRRAVVVAVLFGVQAPRRDVAEGG 229 + PP P P + P +PP P R P P GP P Sbjct: 428 TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP----------------------- 464 Query: 230 LRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGP 274 GR PG P P G P PPRGP Sbjct: 465 ----GRPPGPPPG------------------PPPGLPPGPPPRGP 487 Score = 32.0 bits (71), Expect = 0.98 Identities = 22/59 (37%), Positives = 23/59 (38%), Gaps = 6/59 (10%) Query: 108 PAAPPSSPHAPTRPPPQAVQPRP---SEPTPGSEALPPGSLPEGEPRPYALPPRESPAP 163 P PP P P PPP+ P P P PG PP P G P PP P P Sbjct: 476 PGLPPGPP--PRGPPPRLPPPAPPGIPPPRPGM-MRPPLVPPLGPAPPGLFPPAPLPNP 531 Score = 30.8 bits (68), Expect = 2.2 Identities = 25/79 (31%), Positives = 28/79 (35%), Gaps = 24/79 (30%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPR 164 P P P P P R PP P P P +PP PRP + P P Sbjct: 472 PGPPPGLPPGP--PPRGPP------PRLPPPAPPGIPP-------PRPGMMRPPLVP--- 513 Query: 165 PFRWGDPFSPAPPRPQPPS 183 P PAPP PP+ Sbjct: 514 ------PLGPAPPGLFPPA 526 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 56.6 bits (135), Expect = 4e-08 Identities = 35/94 (37%), Positives = 39/94 (41%), Gaps = 8/94 (8%) Query: 92 SSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPR---PSEPTPGSEALPPGSLPEG 148 + +P +L PA AAPP P P P PQ P + P PGS PP Sbjct: 523 TGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP-----A 577 Query: 149 EPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPP 182 P P LPP P P P P P PP P PP Sbjct: 578 PPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPP 611 Score = 56.2 bits (134), Expect = 5e-08 Identities = 38/107 (35%), Positives = 45/107 (42%), Gaps = 3/107 (2%) Query: 101 LPVSPADPAAPPS-SPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRE 159 LPV+ A P+ + +P PT P + P +EP PG+ PP LP G P P PP Sbjct: 504 LPVAVATPSGGDAPTPGVPTGSPSPDLAPA-AEPAPGAAPPPPPPLP-GLPSPQEAPPSA 561 Query: 160 SPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 P P PAPP P P PP P P P P P Sbjct: 562 PPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP 608 Score = 53.1 bits (126), Expect = 4e-07 Identities = 36/97 (37%), Positives = 39/97 (40%), Gaps = 13/97 (13%) Query: 108 PAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFR 167 PAA P+ AP PPP P P E PP + P+ P LP P P P Sbjct: 532 PAAEPAPGAAPPPPPPLPGLPSPQE-------APPSAPPQAPP----LPGSPEPPPAPPL 580 Query: 168 WGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGP 204 GD P PP P PP PP P P P GP Sbjct: 581 PGDLPPPPPPPPPPPGTDGPVPPPPPP--PPPPPGGP 615 Score = 43.1 bits (100), Expect = 4e-04 Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 25/85 (29%) Query: 106 ADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRP 165 A P+APP +P P P + +P P+ P PG LP PP P P P Sbjct: 557 APPSAPPQAP-----PLPGSPEPPPAPPLPGD--LP--------------PPPPPPPPPP 595 Query: 166 FRWGDPFSPAPPRPQPPSRPAAQPP 190 G P PP P PP P PP Sbjct: 596 GTDG----PVPPPPPPPPPPPGGPP 616 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/108 (32%), Positives = 40/108 (37%), Gaps = 19/108 (17%) Query: 48 VPSG-----LRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLP 102 VP+G L A+P PG A Q +PP SAP + LP Sbjct: 521 VPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPP-----------SAPPQAPPLP 569 Query: 103 VSPADPAAPP---SSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPE 147 SP P APP P P PPP P P P PPG P+ Sbjct: 570 GSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPD 617 >gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sapiens] Length = 1038 Score = 56.2 bits (134), Expect = 5e-08 Identities = 38/124 (30%), Positives = 50/124 (40%), Gaps = 13/124 (10%) Query: 97 RELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPG----SLPEGEPRP 152 R+L P P+ P P PP + PRP+ P PPG S G P Sbjct: 716 RQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASP 775 Query: 153 YALPPRESPAPRPFRWGDPFSPAPPRPQPP---SRPAAQPP------SRPAFRSPRPVRG 203 +PPRE +P+ R P P P PP S P P S P + +P+ ++ Sbjct: 776 PRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQA 835 Query: 204 PHPR 207 P PR Sbjct: 836 PGPR 839 Score = 43.1 bits (100), Expect = 4e-04 Identities = 43/121 (35%), Positives = 52/121 (42%), Gaps = 16/121 (13%) Query: 95 PWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQP---RPSEPTPGSEALPPGSLPEGEPR 151 P E L + P PPSS A T QA+Q R + GS A P P G+ + Sbjct: 681 PPLEDNLFLPPQGGGKPPSS--AQTAEIFQALQQECMRQLQAPAGSPA--PSPSPGGDDK 736 Query: 152 PYALPPRESPAPRPFRWGDPFSPAPPRPQP------PSRPAAQPPSRPAFRSPRPVRGPH 205 P +PPR PRP R SPAPP + P+ P PP P SP+ R P Sbjct: 737 PQ-VPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPL--SPQGSRTPS 793 Query: 206 P 206 P Sbjct: 794 P 794 Score = 31.2 bits (69), Expect = 1.7 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Query: 99 LTLPVSPADPAAP-PSSPHAPTRPPPQ-AVQPRPSEPTPGSEALPPGSLPEGEPRPYALP 156 L +P+ P+ P P++P A RP PQ A+ P+ + T S PG+ P LP Sbjct: 888 LPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSN---PGARPPPPRATARLP 944 Query: 157 PRESPAPRP 165 R P P Sbjct: 945 QRGCPGDGP 953 Score = 30.4 bits (67), Expect = 2.8 Identities = 28/110 (25%), Positives = 40/110 (36%), Gaps = 25/110 (22%) Query: 114 SPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEG--EPRPYALPPRESPAPRPFRWGDP 171 SP PT P + P PS P P + +P+ +P+ +P RP Sbjct: 881 SPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARP------ 934 Query: 172 FSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGP---HPRRAVVVAVLFGV 218 PP R A+ P R P GP P + +A++ GV Sbjct: 935 ---------PPPRATARLPQRGC-----PGDGPEAGRPADKIQMAMVHGV 970 Score = 29.6 bits (65), Expect = 4.9 Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 24/110 (21%) Query: 156 PPRESPAPRPFRWGDPFSPAPPRPQPPSRP----AAQPPSRPAFRSPRPVRGPHPRRAVV 211 P +P P P P +PAP P RP A P + + + P P P RA Sbjct: 882 PEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRAT- 940 Query: 212 VAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGG--LLLVVLHAATVQ 259 + P+R PG P+ GR + + ++H T + Sbjct: 941 ------ARLPQRGC-----------PGDGPEAGRPADKIQMAMVHGVTTE 973 >gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens] Length = 1086 Score = 56.2 bits (134), Expect = 5e-08 Identities = 38/124 (30%), Positives = 50/124 (40%), Gaps = 13/124 (10%) Query: 97 RELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPG----SLPEGEPRP 152 R+L P P+ P P PP + PRP+ P PPG S G P Sbjct: 794 RQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASP 853 Query: 153 YALPPRESPAPRPFRWGDPFSPAPPRPQPP---SRPAAQPP------SRPAFRSPRPVRG 203 +PPRE +P+ R P P P PP S P P S P + +P+ ++ Sbjct: 854 PRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQA 913 Query: 204 PHPR 207 P PR Sbjct: 914 PGPR 917 Score = 43.1 bits (100), Expect = 4e-04 Identities = 43/121 (35%), Positives = 52/121 (42%), Gaps = 16/121 (13%) Query: 95 PWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQP---RPSEPTPGSEALPPGSLPEGEPR 151 P E L + P PPSS A T QA+Q R + GS A P P G+ + Sbjct: 759 PPLEDNLFLPPQGGGKPPSS--AQTAEIFQALQQECMRQLQAPAGSPA--PSPSPGGDDK 814 Query: 152 PYALPPRESPAPRPFRWGDPFSPAPPRPQP------PSRPAAQPPSRPAFRSPRPVRGPH 205 P +PPR PRP R SPAPP + P+ P PP P SP+ R P Sbjct: 815 PQ-VPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPL--SPQGSRTPS 871 Query: 206 P 206 P Sbjct: 872 P 872 Score = 31.2 bits (69), Expect = 1.7 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Query: 99 LTLPVSPADPAAP-PSSPHAPTRPPPQ-AVQPRPSEPTPGSEALPPGSLPEGEPRPYALP 156 L +P+ P+ P P++P A RP PQ A+ P+ + T S PG+ P LP Sbjct: 966 LPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSN---PGARPPPPRATARLP 1022 Query: 157 PRESPAPRP 165 R P P Sbjct: 1023 QRGCPGDGP 1031 Score = 30.0 bits (66), Expect = 3.7 Identities = 27/107 (25%), Positives = 38/107 (35%), Gaps = 18/107 (16%) Query: 114 SPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEG--EPRPYALPPRESPAPRPFRWGDP 171 SP PT P + P PS P P + +P+ +P+ +P RP Sbjct: 959 SPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARP------ 1012 Query: 172 FSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGV 218 PP R A+ P R P G + +V LFG+ Sbjct: 1013 ---------PPPRATARLPQR-GCPGDGPEAGRPADKIQMVEQLFGL 1049 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 55.5 bits (132), Expect = 8e-08 Identities = 65/245 (26%), Positives = 83/245 (33%), Gaps = 57/245 (23%) Query: 49 PSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADP 108 P G R P P G + S SPP + + P P P P Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---PPPPGKP 179 Query: 109 AAPPSS----------PHAPTRPPPQAVQPRPSEPTPGSEALPP---GSLPEGEPRPYAL 155 PP P P PPPQ + R S+ PG PP G+ P+G P P Sbjct: 180 QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP--- 236 Query: 156 PPRESPAPRPFRWGDPFSPAPP-RPQPP-------SRPAAQPPSRPAFRSPRPVRGPHPR 207 P + P P P P PP +PQ P S+ A PP +P + P G +P+ Sbjct: 237 -PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP--QGPPQQEGNNPQ 293 Query: 208 RAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGP 267 G P GG + + P +G RP G P Sbjct: 294 ---------GPPPPA-----GGNPQQPQAPPAGQPQGP-------------PRPPQGGRP 326 Query: 268 SRPPR 272 SRPP+ Sbjct: 327 SRPPQ 331 Score = 52.4 bits (124), Expect = 7e-07 Identities = 39/123 (31%), Positives = 47/123 (38%), Gaps = 26/123 (21%) Query: 102 PVSPADPAAPPSS----------PHAPTRPPPQAVQPRPSEPTPGSEALPP---GSLPEG 148 P P P PP P P PPPQ + R PG PP G+ P+G Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 110 Query: 149 EPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPR----PVRGP 204 P PP P P + G+ P P PP +P PP RSPR +GP Sbjct: 111 PP-----PPPGKPQGPPPQGGN----RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161 Query: 205 HPR 207 P+ Sbjct: 162 PPQ 164 Score = 52.0 bits (123), Expect = 9e-07 Identities = 63/223 (28%), Positives = 79/223 (35%), Gaps = 37/223 (16%) Query: 108 PAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP-RPYALPPRESPAPRPF 166 P PP P P PPPQ P PG PP P+G+ R PP + P P Sbjct: 47 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---PQGDKSRSPRSPPGKPQGPPPQ 103 Query: 167 RWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRP---VRGPHPRRAVVVAVLFGVQAPRR 223 P P PP P P P Q +RP + P P +GP P+ + P+ Sbjct: 104 GGNQPQGPPPP-PGKPQGPPPQGGNRP--QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 160 Query: 224 DVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVA 283 +GG + G P +G P+ G+ P PP P G +PQ Sbjct: 161 PPPQGGNQPQGPPPPPGKPQG--------------PPPQGGKKPQGPP--PPG--KPQGP 202 Query: 284 QRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAP 326 Q +S PG P P QGG P P P Sbjct: 203 PPQGDKSRSSQSPPGK--------PQGPPPQGG-NQPQGPPPP 236 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/134 (28%), Positives = 49/134 (36%), Gaps = 30/134 (22%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGS--EALPPGSLPEGEP------RPY 153 P P P PP + P PPP +P+ P G+ + PP P+G P R Sbjct: 94 PGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151 Query: 154 ALPPRESPAPRPFRWGDPFSPAPP----------------RPQPPSRPAAQPP----SRP 193 PP + P P P P PP P PP +P PP SR Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRS 211 Query: 194 AFRSPRPVRGPHPR 207 + P +GP P+ Sbjct: 212 SQSPPGKPQGPPPQ 225 >gi|41281808 harmonin isoform b3 [Homo sapiens] Length = 899 Score = 55.1 bits (131), Expect = 1e-07 Identities = 57/197 (28%), Positives = 75/197 (38%), Gaps = 27/197 (13%) Query: 47 RVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPA 106 + PS L + P P N H +PP L+ + SS+PW + T P P Sbjct: 556 KTPSALPVMPHPPPSNP----------PHKVPAPPVLPLSGHVSASSSPWVQRTPPPIPI 605 Query: 107 DPAAPPSSPH---APTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAP 163 P PPS P PTRP P A++ S P + + E + ++ P SP P Sbjct: 606 PP--PPSVPTQDLTPTRPLPSALEEALSN-HPFRTGDTGNPVEDWEAKNHSGKPTNSPVP 662 Query: 164 RPFRWGDPFSPAP----PRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQ 219 F P P P PQPP P S+P P P AV VL Sbjct: 663 E-----QSFPPTPKTFCPSPQPPRGPGVSTISKPVMVHQEPNFIYRP--AVKSEVLPQEM 715 Query: 220 APRRDVAEGGLRRDGRR 236 R V + R+D R+ Sbjct: 716 LKRMVVYQTAFRQDFRK 732 Score = 45.8 bits (107), Expect = 7e-05 Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 32/161 (19%) Query: 76 SQSSPPCRRLASYSFWSSAPWRELTLPV---SPADPAAPPSSPHAPTRPPPQAVQPRPSE 132 S +PP RR A + ++ L + P P+A P PH P PP V P Sbjct: 523 SPLAPPLRRFAGGLHLHTTDLDDIPLDMFYYPPKTPSALPVMPHPPPSNPPHKVPAPPVL 582 Query: 133 PTPGSEALPPGSLPEGEPRPYALPPRES----------PAP---------RPFRWGDPFS 173 P G + + P P +PP S P P PFR GD + Sbjct: 583 PLSGHVSASSSPWVQRTPPPIPIPPPPSVPTQDLTPTRPLPSALEEALSNHPFRTGDTGN 642 Query: 174 P----------APPRPQPPSRPAAQPPSRPAFRSPRPVRGP 204 P P P + P + SP+P RGP Sbjct: 643 PVEDWEAKNHSGKPTNSPVPEQSFPPTPKTFCPSPQPPRGP 683 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 54.7 bits (130), Expect = 1e-07 Identities = 75/229 (32%), Positives = 91/229 (39%), Gaps = 33/229 (14%) Query: 110 APPSSPH-APTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRW 168 +P SSP +P + P + P PS P S A P P G P + P PA P Sbjct: 1041 SPSSSPRTSPCQSPTISEGPVPSLPIRPSRA--PSRTP-GPPSAQSSPIDAQPAT-PLPQ 1096 Query: 169 GDPFSPAPPRPQPPSRPAAQPPSRPA--FRSPRP--VRGPHPRRAVVVAVLFGVQAPRRD 224 DP P P+ PP RP A PP+RPA R P P R P P R FG AP+ Sbjct: 1097 KDPAQPLEPKRPPPPRPVA-PPTRPAPPQRPPPPSGARSPAPTRKE-----FG--APK-- 1146 Query: 225 VAEGGLRRDG-RRPGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRGPVGVCRPQVA 283 + G R+D R +PQ G G A P+ PPR V + PQ Sbjct: 1147 -SPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR---------PTIPPRAGV-ISAPQSH 1195 Query: 284 QRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLP--SSLPAPRLHL 330 R R+ S + S PL+ A P SSLP P L Sbjct: 1196 ARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1244 Score = 40.8 bits (94), Expect = 0.002 Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 25/118 (21%) Query: 106 ADPAAP-----PSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRES 160 A PA P P+ P P RPPP P+ P P PP S Sbjct: 1088 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGA-------------RS 1134 Query: 161 PAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRP-----VRGPHPRRAVVVA 213 PAP +G P SP R R +QP + P P R P RA V++ Sbjct: 1135 PAPTRKEFGAPKSPGTTRKDNIGR--SQPSPQAGLAGPGPAGYSTARPTIPPRAGVIS 1190 Score = 39.7 bits (91), Expect = 0.005 Identities = 53/219 (24%), Positives = 70/219 (31%), Gaps = 65/219 (29%) Query: 46 CRVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSP 105 C+ P+ +P +RT +QSSP + A+ P ++ P+ P Sbjct: 1051 CQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPAT-----PLPQKDPAQPLEP 1105 Query: 106 ADP-----AAPPSSPHAPTRPPPQ--AVQPRP---------------------SEPTPGS 137 P APP+ P P RPPP A P P S+P+P + Sbjct: 1106 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQA 1165 Query: 138 EALPPGSLPEGEPRPYALPPRESPAPRP---------------------FRWGDPFSPAP 176 PG RP +PPR P G F P P Sbjct: 1166 GLAGPGPAGYSTARP-TIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1224 Query: 177 PRPQ---------PPSRPAAQPPSRPAFRSPRPVRGPHP 206 +PQ PP Q P P +P P GP P Sbjct: 1225 LKPQAAFPPQSSLPPPAQRLQEPLVPV-AAPMPQSGPQP 1262 Score = 35.4 bits (80), Expect = 0.088 Identities = 44/157 (28%), Positives = 58/157 (36%), Gaps = 24/157 (15%) Query: 58 PIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLP----VSPADPAAPP- 112 P P AR+ A T + + SP R + +P L P S A P PP Sbjct: 1127 PPPSGARSP-APTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPR 1185 Query: 113 ----SSPHAPTRPPPQAVQP----RPSEPTPGSEALPPGSLPEGE-PRPYALPPRES--- 160 S+P + R + P + SE + GS LP P+ P +LPP Sbjct: 1186 AGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1245 Query: 161 ------PAPRPFRWGDPFSPAPPRPQPPSRPAAQPPS 191 AP P P PP+P P SR + PS Sbjct: 1246 EPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPS 1282 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 54.7 bits (130), Expect = 1e-07 Identities = 41/111 (36%), Positives = 47/111 (42%), Gaps = 20/111 (18%) Query: 101 LPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEG-------EPRPY 153 LP P +PP +PT PPP+A S +P E LP LPE E P Sbjct: 441 LPPPEESPLSPPPE-ESPTSPPPEA-----SRLSPPPEELPASPLPEALHLSRPLEESPL 494 Query: 154 ALPPRESPAPRPFRWGDPFSP------APPRPQPPSRPAAQPPSRPAFRSP 198 + PP ESP P PFSP +PP PPS P S P SP Sbjct: 495 SPPPEESPLSPPPE-SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544 Score = 54.7 bits (130), Expect = 1e-07 Identities = 40/117 (34%), Positives = 50/117 (42%), Gaps = 13/117 (11%) Query: 93 SAPWRELTLPVSPADPAAPPSSP--HAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP 150 S P L P+SP A+P S P +P PPP+ + P+ P P + L P E Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL---PTSPPPEASRLSPPP----EE 578 Query: 151 RPYALPPRESPA---PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGP 204 P + PP ESP P R PF +P P P P + PP SP P P Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL-SPPPEDSP 634 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/118 (34%), Positives = 54/118 (45%), Gaps = 23/118 (19%) Query: 103 VSPADPAAP----PSSPHAPTRPPPQAVQPRPSEPTPGSE-ALPPGSLPEGE-----PRP 152 ++P+ P+ P P S P PP + PRP P P S ALPP SLP P Sbjct: 2358 LAPSPPSHPDIFRPGSYTDPYAQPP--LTPRPQPPPPESCCALPPRSLPSDPFSRVPASP 2415 Query: 153 YALPPRESP-APRPFRWGDPFSPAPPRPQ---------PPSRPAAQPPSRPAFRSPRP 200 + +SP PRP + F P+P P+ PPSRP ++ P P + PRP Sbjct: 2416 QSQSSSQSPLTPRPLS-AEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP 2472 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 12/128 (9%) Query: 49 PSGLRRLADPIPG---NARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSP 105 P L++ +PG ++ + +++ PP + +Y+ S+ R+L+ P P Sbjct: 4854 PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNV-SNLDVRQLSAP--P 4910 Query: 106 ADPAAPPSSPHAPT--RPPPQAVQPRPSEPT---PGSEALPPGSLPEG-EPRPYALPPRE 159 + +PP SP AP+ PP + + P+EP P LP S PE P+P A PP E Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970 Query: 160 SPAPRPFR 167 RP R Sbjct: 4971 GEDSRPPR 4978 Score = 45.8 bits (107), Expect = 7e-05 Identities = 37/111 (33%), Positives = 41/111 (36%), Gaps = 11/111 (9%) Query: 101 LPVSPADPAAPPSSP--HAPTRPPPQAVQPRPSEPTPGSEALPPG-----SLPEGEPRPY 153 LP SP A S P +P PPP+ P P P S P S PE P Sbjct: 474 LPASPLPEALHLSRPLEESPLSPPPEE---SPLSPPPESSPFSPLEESPLSPPEESPPSP 530 Query: 154 ALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGP 204 AL SP P PF +P P P P + PP SP P P Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL-SPPPEESP 580 Score = 45.4 bits (106), Expect = 9e-05 Identities = 35/105 (33%), Positives = 44/105 (41%), Gaps = 16/105 (15%) Query: 102 PVSPADPAAPPSSPHAPTR--PPPQ--AVQPRPSE----PTPGSEALPPGSL-----PEG 148 P+SP +P S P +R PPP+ + P P E P P L P + P Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666 Query: 149 EPRPYALPPRESPA---PRPFRWGDPFSPAPPRPQPPSRPAAQPP 190 E P + PP ESP P R P +P P P PA+ PP Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711 Score = 45.1 bits (105), Expect = 1e-04 Identities = 49/154 (31%), Positives = 60/154 (38%), Gaps = 27/154 (17%) Query: 76 SQSSPPCRRLASY----SFWSSAPWRELTLPVSPAD-PAAPP--SSPHAPTRP----PPQ 124 S+ SPP L + + S P E L P + P +PP SSP +P PP+ Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524 Query: 125 AVQPRPSEPTPGSEALPPGSLPEGEP---RPYALPPRE---SPAPRPFRWG-----DPFS 173 P P+ TP S PP + P P P + PP E SP P R P S Sbjct: 525 ESPPSPALETPLSP--PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582 Query: 174 PAP---PRPQPPSRPAAQPPSRPAFRSPRPVRGP 204 P P P PP PP + SP P P Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEESP 616 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 20/134 (14%) Query: 108 PAAPPSSPHAPT------------RPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYAL 155 PA P + H+ T PPP+ P PS P + P L E P A Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943 Query: 156 PPRESPAPRPFRWGDPFSPAPPRPQPPSRP--AAQPPSRPAFRSPRPVRGPHPRRAVVVA 213 PP SP P SP RP+P +RP + P + + VR R + + Sbjct: 4944 PPVPSPLPL------ASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQ 4997 Query: 214 VLFGVQAPRRDVAE 227 G Q R+VAE Sbjct: 4998 KGSGRQEDEREVAE 5011 Score = 44.3 bits (103), Expect = 2e-04 Identities = 46/160 (28%), Positives = 57/160 (35%), Gaps = 13/160 (8%) Query: 44 GRCRVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPV 103 G+C P L P PG E PP L S + L+ + Sbjct: 872 GQCPAPEELPLF--PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929 Query: 104 SPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPR-PYALPPRESP- 161 P DP PP SP PP A+ P G P G+ + +P P A P E+P Sbjct: 930 MPPDPLPPPLSPIITAAAPP-ALSPL------GELEYPFGAKGDSDPESPLAAPILETPI 982 Query: 162 -APRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRP 200 P DP P PP PPS + P+ P P P Sbjct: 983 SPPPEANCTDP-EPVPPMILPPSPGSPVGPASPILMEPLP 1021 Score = 42.0 bits (97), Expect = 0.001 Identities = 50/192 (26%), Positives = 63/192 (32%), Gaps = 40/192 (20%) Query: 93 SAPWRELTLPVSPADPAAPPSS--PHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP 150 S P E L P +P P S PH RP + PRP EP +A P P+ E Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE- 775 Query: 151 RPYALPPRESPAPRPFRWGDPFSPAPPR----PQPPSRPAAQPPSRPAFRSPRPVRGPHP 206 P E P P G SP P PQ + P P SP+P Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL-SPQP------ 828 Query: 207 RRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGRG 266 E L P L+P+ L + +++P L Sbjct: 829 -------------------EESHLSPQSEEPCLSPRPEESHL------SPELEKPPLSPR 863 Query: 267 PSRPPRGPVGVC 278 P +PP P G C Sbjct: 864 PEKPPEEP-GQC 874 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/122 (30%), Positives = 45/122 (36%), Gaps = 23/122 (18%) Query: 102 PVSPADPAAPPSSP-----------HAPTRPPPQAVQPRPSEPTPGSEAL--PPGSLPEG 148 P+SP +P S P +P PPP + P P P + L PP P Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPP---EESPLSPPPEASRLSPPPEDSPMS 636 Query: 149 EP---RPYALPP---RESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVR 202 P P + PP R SP P R P +P P P P + PP SP P Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL-SPPPED 695 Query: 203 GP 204 P Sbjct: 696 SP 697 Score = 39.7 bits (91), Expect = 0.005 Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 13/113 (11%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYAL----PP 157 P+SP +P S P +R P V R S P S PP P P A PP Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693 Query: 158 RESPAPRPFRWGDPFSPAPPRPQPP--SRPAAQPPSRPAFRSPR---PVRGPH 205 +SP P SPA P P+ S P + P P P+ GPH Sbjct: 694 EDSPTSPP----PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPH 742 Score = 36.6 bits (83), Expect = 0.040 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPT----PGSEALPPGSLPEGEPRPYALPP 157 P+SP P PP P P + P P EP+ G AL P P P LP Sbjct: 859 PLSPR-PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917 Query: 158 RESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPS 191 S P P P PP P P AA PP+ Sbjct: 918 SPSGEPSLSPQLMPPDPLPP-PLSPIITAAAPPA 950 Score = 35.8 bits (81), Expect = 0.068 Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 19/101 (18%) Query: 112 PSSPHAPTRPPPQAVQP----RPSEPTPGSEAL------PPGSLPEGEPRP----YALPP 157 P P A PPP A P+ P S + P GS+P G P LPP Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVP-GPDSPGELFLKLPP 2165 Query: 158 RESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSP 198 + PA P + DPF AP P P P A PP+ P + SP Sbjct: 2166 -QVPAQVPSQ--DPFGLAPAYPLEPRFPTA-PPTYPPYPSP 2202 Score = 35.8 bits (81), Expect = 0.068 Identities = 71/253 (28%), Positives = 87/253 (34%), Gaps = 34/253 (13%) Query: 128 PRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWG---DPFSPAP----PRPQ 180 PR S+ P S L G P+ P AL P P FR G DP++ P P+P Sbjct: 2333 PRASQVEPQSPGL--GLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390 Query: 181 PPSRPAAQP----PSRPAFRSPRPVRGPH-------PRRAVVVAVLFGVQAPRRDVAEGG 229 PP A P PS P R P + PR A PR + Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450 Query: 230 LRRDGR---RPGLAP--QRGRGGLLLVVLHAATVQRPRLGRG--PSRPPRGPVGVCRPQV 282 R R R AP + R V A ++ LG G P+ P GP G +V Sbjct: 2451 SRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510 Query: 283 AQRQRLARVCVRSLPGNRRLATRSCPAAFPLQ---GGATLPSSLPAPRLHLGSLLPSSSG 339 Q VRS PG P F G +L +P P L + S G Sbjct: 2511 PSGQ--PPNFVRS-PGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567 Query: 340 -GARLGDAAGTTH 351 G LG T + Sbjct: 2568 PGPTLGKPQSTNY 2580 Score = 35.4 bits (80), Expect = 0.088 Identities = 32/116 (27%), Positives = 42/116 (36%), Gaps = 33/116 (28%) Query: 102 PVSPADPAAPPSSPH------APTRPPPQAVQPRPSEPTPGS-EALPPGSLPEGEPRPYA 154 P+ P P APP+ P AP +PP RP PG PPG+ Sbjct: 2184 PLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGT---------- 2233 Query: 155 LPPRESPA-PRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAF---RSPRPVRGPHP 206 PR P+ P PF +P+ PS P P ++ P+ P P Sbjct: 2234 --PRHQPSTPDPFL----------KPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277 Score = 34.7 bits (78), Expect = 0.15 Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 25/133 (18%) Query: 101 LPVSPADPAAPPSSPHAPTRPPPQAVQPRPSE-------------PTPGSEALPPGSLPE 147 +P P P S +P P + PRP E P P PG P Sbjct: 818 VPEEPCLSPQPEESHLSPQSEEP-CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPA 876 Query: 148 GEPRPYALPPRESPAPRPFRWGDPFSPAPPRP-------QPPSRPAAQPPSRPAFRSPRP 200 E P PP E P+ P G+P P P + P P+ +P P P P Sbjct: 877 PEELPLFPPPGE-PSLSPL-LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934 Query: 201 VRGPHPRRAVVVA 213 + P P ++ A Sbjct: 935 L--PPPLSPIITA 945 Score = 34.3 bits (77), Expect = 0.20 Identities = 42/147 (28%), Positives = 49/147 (33%), Gaps = 32/147 (21%) Query: 74 DHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRP--- 130 + S SPP S S P P P +PP +PT PPP+A + P Sbjct: 640 EESPMSPP----PEVSRLSPLPVVSRLSPPPEESPLSPPPE-ESPTSPPPEASRLSPPPE 694 Query: 131 ----SEPTPGSEALPPG-----SLPEGEP-------RPYALPPRESPAPRPFRWGDPFSP 174 S P S A PP SLP E P P E P P P Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP-------RP 747 Query: 175 APPRPQP-PSRPAAQPPSRPAFRSPRP 200 P P P P P + SP+P Sbjct: 748 EEPHLSPRPEEPHLSPQAEEPHLSPQP 774 Score = 33.5 bits (75), Expect = 0.34 Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 103 VSPADPAAPPSSPHAPTRPP----PQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPP 157 + P P PPSSP P RP P + P ++ P P P EP P + P Sbjct: 4302 LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360 Score = 33.1 bits (74), Expect = 0.44 Identities = 41/160 (25%), Positives = 57/160 (35%), Gaps = 31/160 (19%) Query: 59 IPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADP-AAPPSSP-- 115 +P + + V + Q S SP R S + +P +T DP + PPS P Sbjct: 2403 LPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP---VTPRFQSPDPYSRPPSRPQS 2459 Query: 116 -------HAPTRPPPQAVQPRPSEPTPGS-------EALPPG-------SLPEGEPRPYA 154 H P RP P V + S ALP G +P G+P + Sbjct: 2460 RDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFV 2519 Query: 155 LPPRESP---APRPFRWGDPFSPAPPRPQPP-SRPAAQPP 190 P P P R+ P + P +PP +P PP Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPP 2559 Score = 32.3 bits (72), Expect = 0.75 Identities = 35/121 (28%), Positives = 42/121 (34%), Gaps = 25/121 (20%) Query: 102 PVSPAD-PAAPPSSPHAPTRPPPQA---VQPRPSEPTP-----------GSEALPPGSLP 146 P P D P P + + + P+ +P EP P G + P P Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433 Query: 147 EGEPRPYALPPRESPAPRPFRWGDPFSPAPP----RPQPPSRPAAQPP-----SRPAFRS 197 E P PP ESP P P SP P P P PA+ P SRP S Sbjct: 434 LNEEMPLLPPPEESPLSPPPE-ESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492 Query: 198 P 198 P Sbjct: 493 P 493 Score = 32.0 bits (71), Expect = 0.98 Identities = 39/131 (29%), Positives = 45/131 (34%), Gaps = 27/131 (20%) Query: 101 LPVSPADPAAPPSSPHAPTRPPPQAV---QPR----PSEPTPGSEALPPGSLPEGEPRPY 153 L S A PP P Q + QP+ P T + L G P+G PR Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290 Query: 154 ALPPRESPAPRPFRWGDPFSPAPP--RPQPPSRP-------------AAQPPSRPAFRSP 198 A P S P P P PP PQ P RP A PP+ P P Sbjct: 4291 APPGALSTGPVL----GPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346 Query: 199 R-PVRGPHPRR 208 + P P P R Sbjct: 4347 QGPTLEPPPGR 4357 Score = 31.6 bits (70), Expect = 1.3 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 134 TPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRP 193 TP + + P S P RP PP ++ AP P P P RP + P AQPP P Sbjct: 2332 TPRASQVEPQS-PGLGLRPQEPPPAQALAPSP-----PSHPDIFRPGSYTDPYAQPPLTP 2385 Query: 194 AFRSPRP 200 + P P Sbjct: 2386 RPQPPPP 2392 Score = 29.6 bits (65), Expect = 4.9 Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 7/62 (11%) Query: 111 PPSSPHAPTRPP-PQAVQPRPSEPTP----GSEAL--PPGSLPEGEPRPYALPPRESPAP 163 PP P AP P ++ P P P G E + PP S G P P AL + P Sbjct: 2930 PPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCE 2989 Query: 164 RP 165 P Sbjct: 2990 DP 2991 Score = 29.3 bits (64), Expect = 6.3 Identities = 49/192 (25%), Positives = 65/192 (33%), Gaps = 36/192 (18%) Query: 71 EQRDHSQSSPPCRRLA-SYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPR 129 E S P C L S + +P +L+ P PA S P + Sbjct: 1072 EMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAP 1131 Query: 130 PSEPTPGSEALPPGSL-PEGEPRPYALPPRESPAPRPFR----------WGDPFSP---- 174 S+P PG PGSL E + P L P E P G P Sbjct: 1132 GSQPEPGQ---TPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEP 1188 Query: 175 -APPRPQPPS----------RPAAQPPSRPAFRSPRPVRG-PHPRRAVVVAVLFGVQ--- 219 AP P PP+ +Q + +F P+ G P P +++ GV Sbjct: 1189 RAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDV 1248 Query: 220 APRRDVAEGGLR 231 +P RD EG LR Sbjct: 1249 SPARD--EGSLR 1258 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 54.7 bits (130), Expect = 1e-07 Identities = 60/234 (25%), Positives = 82/234 (35%), Gaps = 38/234 (16%) Query: 106 ADPAAPPSSPHAPTRPPPQAVQPRPSEPTP--GSEALPPGSLPEGEPRPYALPPRESPAP 163 A+ P + PPP P PS P P PP L P P + PP SP P Sbjct: 387 AEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPP 446 Query: 164 RPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRR 223 P + SP P P SR +PP P+ R+ R P P Sbjct: 447 PPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT-------SPPTPTP 499 Query: 224 DVAEGGLRRDGRRPGLAPQ-----RGRGGLLLVVLHAAT---VQRPR--LGRGPSRPPRG 273 A GG D P +AP+ + ++ V+ A + ++ PR + P +PP+ Sbjct: 500 STATGGPPEDS--PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV 557 Query: 274 PVG-VCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQGGATLPSSLPAP 326 V V RP + + + PA P A P S P P Sbjct: 558 EVSPVLRPPITTSPPVPQE----------------PAPVPSPPRAPTPPSTPVP 595 Score = 51.2 bits (121), Expect = 2e-06 Identities = 36/99 (36%), Positives = 38/99 (38%), Gaps = 7/99 (7%) Query: 107 DPAAPPSSPHAPT-RPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRP 165 DP PP +P RPP P P EP P P P P P R Sbjct: 550 DPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSP-PRAPTPPSTPVPLPEKRRSILREPT 608 Query: 166 FRWGD---PFSPAPPRPQPPSRPAAQPPSRPAFRSPRPV 201 FRW P PP P PP PA PP PA S RP+ Sbjct: 609 FRWTSLTRELPPPPPAPPPP--PAPSPPPAPATSSRRPL 645 Score = 44.3 bits (103), Expect = 2e-04 Identities = 38/120 (31%), Positives = 52/120 (43%), Gaps = 24/120 (20%) Query: 94 APWRELTLPVSPADPAAPPSSP------------HAPTRPPPQAVQPRPSEPTPGSEALP 141 +P + L P+ P +APP +P ++P+R P V P P+PGS + Sbjct: 1836 SPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL-PSPGSPSSL 1894 Query: 142 PGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQP-PSRPAFRSPRP 200 +P + PPR S P SP PRP PPSR A+ P + P R P P Sbjct: 1895 THHIPTVGDPDFPAPPRRSRRP---------SPLAPRP-PPSRWASPPLKTSPQLRVPPP 1944 Score = 35.4 bits (80), Expect = 0.088 Identities = 42/147 (28%), Positives = 54/147 (36%), Gaps = 38/147 (25%) Query: 100 TLPVSPADPAAPPSSPHAPTRPPP------------------------QAVQPRPSEPTP 135 T P P +PA PS P APT P + P P+ P P Sbjct: 569 TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPP 628 Query: 136 GSEALPPGSLPEGEPRPYAL-PPRESPAPRPFRWGD-----PFSPAPPRPQPPSRPAAQP 189 + + PP RP L P+ +P+ + + P AP P+P PA Sbjct: 629 PAPSPPPAPATSSR-RPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS 687 Query: 190 PSRPAFRSPRPV-RGPH---PRRAVVV 212 P+ P PR V R H PR A VV Sbjct: 688 PAEP---EPRAVGRTNHLSLPRFAPVV 711 Score = 35.4 bits (80), Expect = 0.088 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 9/93 (9%) Query: 96 WRELTLPVSPADPAAPP----SSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPR 151 W LT + P PA PP S P AP + + R + TP L + E Sbjct: 611 WTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL---KIYESVLT 667 Query: 152 PYALPPRESPAPRPFRWGDPFSPAPPRPQPPSR 184 P L E+P P P D SPA P P+ R Sbjct: 668 PPPLGAPEAPEPEPPPADD--SPAEPEPRAVGR 698 Score = 35.4 bits (80), Expect = 0.088 Identities = 40/169 (23%), Positives = 53/169 (31%), Gaps = 74/169 (43%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRPSEPT---------PGSEALPPGSLPE-------- 147 P + + PP+ P A P Q + P++PT PG L G PE Sbjct: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSK 2190 Query: 148 ---------------GEPRPYALPPRESPAP------RPFRWGDP-------------FS 173 GE P P ++ P P P W P Sbjct: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250 Query: 174 PAPPRPQPP------SRPAA-----------------QPPSRPAFRSPR 199 PAPP P PP S PA+ PP+ P +++PR Sbjct: 2251 PAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPR 2299 Score = 31.2 bits (69), Expect = 1.7 Identities = 44/174 (25%), Positives = 61/174 (35%), Gaps = 46/174 (26%) Query: 121 PPPQAVQPRPSEP-TPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRP 179 PPP+ P+ P TP + G+ + L ++P R +P +P R Sbjct: 162 PPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRG 221 Query: 180 QPPSRPAAQPPSR---------------PAFRSPRPV-------------RGPHPRRAVV 211 +PP RPA P R P P PV GP P Sbjct: 222 RPPGRPAG--PCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGP----- 274 Query: 212 VAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATVQRPRLGR 265 G PRR GG G R G RG GGL V+ + ++ ++G+ Sbjct: 275 -----GPGTPRR----GGQSSRGGRGGRGRGRG-GGLPFVIKFVSRAKKVKMGQ 318 Score = 28.9 bits (63), Expect = 8.3 Identities = 27/95 (28%), Positives = 33/95 (34%), Gaps = 11/95 (11%) Query: 111 PPSSPHAPTRPPPQAVQ-------PR--PSEPTPGSEALPPGSLPEGEPRPYALPPRESP 161 PP + +P P P+AV PR P TP + P P P P Sbjct: 681 PPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQP 740 Query: 162 APRPFRWGDPFSPAPPRPQ--PPSRPAAQPPSRPA 194 P + PP+PQ PP P PP A Sbjct: 741 LQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKA 775 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 54.7 bits (130), Expect = 1e-07 Identities = 96/356 (26%), Positives = 120/356 (33%), Gaps = 61/356 (17%) Query: 38 LPLAAGGRCRVPSGLRRLADPIPGNARAGVARTEQRDHSQSSPPCRRLASYSFWSSAPWR 97 LP +A P GL + A P A T Q + +PP S P Sbjct: 588 LPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQP--APQAPPA---------VSTP-- 634 Query: 98 ELTLPVSPADPAA--PPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP---RP 152 LP+ P A PP +P PPQA P+PS PG A P + G+P P Sbjct: 635 ---LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS---PGL-ASSPEKIVLGQPPSATP 687 Query: 153 YALPPRESPAPRPFRWGDPFSPAPPRPQPPSR--PAAQPPSRPAFRSPRPVRGPHPRRAV 210 A+ ++S F P QP S P P+ +P P + P P V Sbjct: 688 TAILTQDSL--------QMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV 739 Query: 211 VVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVL-HAAT------VQRPRL 263 G QAP + + P AP +G G L H A + P Sbjct: 740 AKGAGLGPQAPDSQASPAPA---PQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHP 796 Query: 264 GRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQG--GATLPS 321 R PSRPP P V RP P A + P F +Q G P+ Sbjct: 797 TRPPSRPPSRPQSVSRPPSEPPLH---------PCPPPQAPPTLPGIFVIQNQLGVPPPA 847 Query: 322 SLPAPRL---HLGSLLPSSSGGARLGDAAGTTHFQPAHLSHAAAPASLTDHSFARP 374 S PAP L P S G H P+ S A A +S T P Sbjct: 848 SNPAPTAPGPPQPPLRPQSQPPE--GPLPPAPHLPPSSTSSAVASSSETSSRLPAP 901 Score = 50.1 bits (118), Expect = 3e-06 Identities = 67/255 (26%), Positives = 87/255 (34%), Gaps = 53/255 (20%) Query: 93 SAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP-- 150 SA L++P S A PP+ AP P + P P + P +P P Sbjct: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769 Query: 151 ---------RPYALPPRES---PAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSP 198 P+ P +S P+P P R P S P RPQ SRP ++PP P P Sbjct: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTR---PPSRPPSRPQSVSRPPSEPPLHPC---P 823 Query: 199 RPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRRPGLAPQRGRGGLLLVVLHAATV 258 P P V+ GV P + A +P L PQ Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPAP--TAPGPPQPPLRPQ---------------- 865 Query: 259 QRPRLGRGPSRPPRGPVGVCRPQVAQRQRLARVCVRSLPGNRRLATRSCPAAFPLQ---G 315 S+PP GP+ P + + V S +R A P+ F LQ Sbjct: 866 ---------SQPPEGPLPPA-PHLPPSSTSSAVASSSETSSRLPA--PTPSDFQLQFPPS 913 Query: 316 GATLPSSLPAPRLHL 330 S P P LHL Sbjct: 914 QGPHKSPTPPPTLHL 928 Score = 41.2 bits (95), Expect = 0.002 Identities = 38/109 (34%), Positives = 46/109 (42%), Gaps = 15/109 (13%) Query: 111 PPSSPHAPTRP----PPQAVQPRPSE-PTPGSEALPPGSLPEGEPRPYALPPR-ESPAPR 164 PP+S APT P PP Q +P E P P + LPP S R +P P Sbjct: 845 PPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904 Query: 165 PFRWGDPFSPAPPR-PQPP------SRPAAQPPSRPAFRSPRPVRGPHP 206 F+ P S P + P PP PAA PP P R+ + V P P Sbjct: 905 DFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP--RTFQMVTTPFP 951 Score = 39.3 bits (90), Expect = 0.006 Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 7/106 (6%) Query: 100 TLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALP--- 156 T P P P P S P PP + P + S + LP P + L Sbjct: 853 TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP 912 Query: 157 ---PRESPAPRPFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPR 199 P +SP P P P APP P P + P PA P+ Sbjct: 913 SQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF-PALPQPK 957 Score = 33.1 bits (74), Expect = 0.44 Identities = 37/147 (25%), Positives = 49/147 (33%), Gaps = 10/147 (6%) Query: 105 PADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPR 164 P P A P RPPP P P+ G+ PP + PE +P A P + Sbjct: 1333 PPPPPATLKVAEPPPRPPPP---PPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRK 1389 Query: 165 PFRWGDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLF------GV 218 +R + P P P R P+ + G A V L+ Sbjct: 1390 TYR-ENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPP 1448 Query: 219 QAPRRDVAEGGLRRDGRRPGLAPQRGR 245 P A+G D PGL P + R Sbjct: 1449 PEPAASAAQGTGDPDWEAPGLPPAKRR 1475 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.137 0.435 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,166,933 Number of Sequences: 37866 Number of extensions: 1799836 Number of successful extensions: 38609 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 713 Number of HSP's successfully gapped in prelim test: 2056 Number of HSP's that attempted gapping in prelim test: 13046 Number of HSP's gapped (non-prelim): 13913 length of query: 389 length of database: 18,247,518 effective HSP length: 104 effective length of query: 285 effective length of database: 14,309,454 effective search space: 4078194390 effective search space used: 4078194390 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.