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Search of human proteins with 118498359
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
(490 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens] 961 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 68 2e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 60 4e-09
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 60 4e-09
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 59 1e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 58 2e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 58 2e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 58 2e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 58 2e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 58 2e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|104526627 triadin [Homo sapiens] 54 2e-07
gi|4557509 cylicin 2 [Homo sapiens] 53 7e-07
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 52 9e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 52 1e-06
gi|15431288 ribosomal protein L10a [Homo sapiens] 52 2e-06
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 51 2e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 51 3e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 51 3e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 50 4e-06
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 50 4e-06
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 50 4e-06
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 50 4e-06
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 50 4e-06
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 50 4e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 4e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 50 4e-06
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 50 5e-06
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 50 5e-06
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 50 5e-06
>gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
Length = 490
Score = 961 bits (2485), Expect = 0.0
Identities = 490/490 (100%), Positives = 490/490 (100%)
Query: 1 MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLNE 60
MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLNE
Sbjct: 1 MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLNE 60
Query: 61 NESLFLMVVLWKIPSKELRVRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNK 120
NESLFLMVVLWKIPSKELRVRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNK
Sbjct: 61 NESLFLMVVLWKIPSKELRVRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNK 120
Query: 121 HGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVP 180
HGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVP
Sbjct: 121 HGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVP 180
Query: 181 VSVNLLSKNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEK 240
VSVNLLSKNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEK
Sbjct: 181 VSVNLLSKNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEK 240
Query: 241 LPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQK 300
LPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQK
Sbjct: 241 LPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQK 300
Query: 301 ERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNE 360
ERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNE
Sbjct: 301 ERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNE 360
Query: 361 SEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAE 420
SEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAE
Sbjct: 361 SEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAE 420
Query: 421 SETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKW 480
SETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKW
Sbjct: 421 SETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKW 480
Query: 481 PKKPKVPQST 490
PKKPKVPQST
Sbjct: 481 PKKPKVPQST 490
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 68.2 bits (165), Expect = 2e-11
Identities = 67/249 (26%), Positives = 104/249 (41%), Gaps = 23/249 (9%)
Query: 238 SEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFE 297
++K PEK +S VK+ + A P+ + E K+ + KE + + +
Sbjct: 778 ADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK--V 835
Query: 298 KQKERKKKRQQARKTASVLSKDDVAPESG---DTTVKKPESKKEQTPEHGKKKRGRGKAQ 354
K+ +K + ++A T K D E + K E KKE E K+ + K +
Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895
Query: 355 V----KATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKAL 410
K E E P V + + EK E+ K + AK+ PS P KK A
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK---EPDDAKAKEPSKPAEKKEAAP 952
Query: 411 PASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSV 470
+T E K PE+KPK + +A KE +L K+ P KP+A+ S +
Sbjct: 953 EKKDT-----KEEKAKKPEEKPKTEAKA-KEDDKTLSKE-----PSKPKAEKAEKSSSTD 1001
Query: 471 RKASHTPKK 479
+K S P+K
Sbjct: 1002 QKDSKPPEK 1010
Score = 65.9 bits (159), Expect = 8e-11
Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 29/260 (11%)
Query: 240 KLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQ 299
K PEK +S + K+ + A P+ K + +K ++ K ++ EK
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPV------------KAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 300 KER-KKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKK-RGRGKAQVKA 357
K K++ + K S + ++ +PE K P ++ +TPE K + K+ KA
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKA----KSPVKEEAKTPEKAKSPVKEEAKSPEKA 750
Query: 358 TNESEDEIPQLVPIGKKTPANEKVEI------QKHATGKKSPAKSPNPSTPRGKKRKALP 411
+ + + + KTPA E+ +K + K KSP + K+ P
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810
Query: 412 ASETPKAAESETPGKSPEKKPKIK-----EEAVKEKSPSLGKKDARQTPKKPEAKFFTTP 466
E PK E ++P K EK ++K ++A +EK+P+ K + ++ KK EA P
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP 870
Query: 467 SKSVRKASHTPKKWPKKPKV 486
V + + PK+ KV
Sbjct: 871 KPKVEEKKEPAVEKPKESKV 890
Score = 65.5 bits (158), Expect = 1e-10
Identities = 70/267 (26%), Positives = 116/267 (43%), Gaps = 31/267 (11%)
Query: 240 KLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQ 299
K PEK E+ VK+ + A P S + + + K+EA+ ++ K+
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 300 KERKKKRQQARKTASVLSKDDV-APESGDTTVKKPESKKEQTPEHGK-------KKRGRG 351
+ + ++ + A +K++ +PE K PE ++ ++PE K K +
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKA----KSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 352 KAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNP-----STPRGKK 406
K+ VKA +S ++ V K+P K +++ A KSP K+ +P TP K
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA---KSPEKAKSPVKEEAKTPEKAK 737
Query: 407 RKALPASETPKAAESETPG-----KSPEKKPKIKEEA--VKEKSPSLGKKDARQTPKKPE 459
+++P+ A+S KSPE K KEEA +K P K ++ K PE
Sbjct: 738 SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 460 AKFFTTPSKSVRKASHTPKKWPKKPKV 486
+P K KA K+ PKK +V
Sbjct: 798 KA--KSPLKEDAKAPE--KEIPKKEEV 820
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/243 (25%), Positives = 107/243 (44%), Gaps = 34/243 (13%)
Query: 272 DEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVK 331
+++ K +++ +++ E + E E++KE K++ + + ++ E G+ K
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGG-----EEEEAEGGEEETK 502
Query: 332 KPESKKEQTPEHGK----KKRGRGKAQVKATNESEDEIPQLV--PIGKKTPANEKVEIQK 385
P +++ +PE K+ + A+ K+ + E + P V P K+PA E+ +
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562
Query: 386 HA-TGKKSPAKSP-NPSTPRGKKRKALPASETPKAAESETPGKSP---------EKKPKI 434
A + +K AKSP +P K A +++P A+S KSP E K +
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV 622
Query: 435 KEEA---VKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPK-------KWPKKP 484
KEEA + KSP K ++ K PE +P K K+ K K P+K
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKA--KSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 485 KVP 487
K P
Sbjct: 681 KSP 683
Score = 60.1 bits (144), Expect = 4e-09
Identities = 80/303 (26%), Positives = 122/303 (40%), Gaps = 64/303 (21%)
Query: 240 KLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQ 299
K PEK +S K+ + A P+ + T + K+EA+ + ++ EK
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKE------EAKTPEKAKSPVKEEAKSPEKAKSPEKA 756
Query: 300 KERKKKRQQARKTAS--VLSKDDVAPESGDTTVKK----PESKKEQTPEHGK--KKRGRG 351
K K +A+ A S D PE + VK+ PE K E K +K
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816
Query: 352 KAQVKATNESEDEIPQLVPIGK--------KTPANEKVEIQKHATGKKSPAK-SPNPSTP 402
K +VK+ + E+E PQ V + + K PA K E +K + +++P K +P P
Sbjct: 817 KEEVKSPVK-EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 403 RGKKRKALPASETPKAAESE-------------TPGKSPEKKPKIKEEAVKEKSPSLGKK 449
K+ PA E PK ++ E TP K K ++KE+A ++ + KK
Sbjct: 876 EKKE----PAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 450 ---DAR-QTPKKPEAKFFTTPSKS------VRKASHTPK-------------KWPKKPKV 486
DA+ + P KP K P K +K PK K P KPK
Sbjct: 932 EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Query: 487 PQS 489
++
Sbjct: 992 EKA 994
Score = 59.3 bits (142), Expect = 8e-09
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 17/208 (8%)
Query: 283 KKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE 342
+K+EA+ ++ EK K K+ ++ A K++ VK PE K E
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA---KSPAEVKSPEKAKSPAKE 590
Query: 343 HGK-----KKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSP 397
K K + K+ VK +S E V K+PA K +K + K AKSP
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP-EKAKSPTKEEAKSP 649
Query: 398 NPS-TPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDAR---- 452
+ +P ++ K+ +++P AE+++P K+ K P E EK+ S K++A+
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA--KSPVKAEAKSPEKAKSPVKEEAKSPEK 707
Query: 453 -QTPKKPEAKFFTTPSKSVRKASHTPKK 479
++P K EAK V++ + TP+K
Sbjct: 708 AKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Score = 59.3 bits (142), Expect = 8e-09
Identities = 55/217 (25%), Positives = 105/217 (48%), Gaps = 17/217 (7%)
Query: 282 KKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTP 341
K ++A+ +E + + ++++A+ A V S + + + E+K +
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604
Query: 342 EHGKKKRGRGKAQVKATNESEDEIPQLV--PIGKKTPANEKVEI-QKHATGKKSPAKSPN 398
+ K+ + A+ K+ + E + P V P K+P E+ + +K + +K AKSP
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE 664
Query: 399 PS-TPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVK-EKSPSLGKKDAR---- 452
+ +P + K+ +++P AE+++P K+ K +KEEA EK+ S K++A+
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKA---KSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 453 -QTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQ 488
++P K EAK TP K+ K P+K K P+
Sbjct: 722 AKSPVKEEAK---TPEKAKSPVKEEAKS-PEKAKSPE 754
Score = 56.2 bits (134), Expect = 6e-08
Identities = 65/259 (25%), Positives = 94/259 (36%), Gaps = 17/259 (6%)
Query: 240 KLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQ 299
K PEK +S K+ + A P+ S E K + + K + K + K
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKS--PEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 300 KERKKKRQQARKTASVLSKDDVAP---ESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVK 356
E+ K ++A KT V S + P E+ K PE K E K +
Sbjct: 747 PEKAKSPEKA-KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 357 ATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPR-----GKKRKALP 411
E EIP+ + EK + K K + P+TP+ K++ P
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 412 ASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK--KDARQTPKKPEAKFFTTPSKS 469
E PK E + EK + K EA KE++ K ++ P K E K P +
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK 925
Query: 470 VRKASHTP----KKWPKKP 484
A P K P KP
Sbjct: 926 TEVAKKEPDDAKAKEPSKP 944
Score = 50.4 bits (119), Expect = 4e-06
Identities = 56/215 (26%), Positives = 92/215 (42%), Gaps = 37/215 (17%)
Query: 298 KQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKA 357
K +E+ K +++ K ++ ++ E+ T E +KE E GK++ G G+ +
Sbjct: 439 KSEEKIKVVEKSEKETVIV--EEQTEETQVTEEVTEEEEKEAKEEEGKEEEG-GEEEEAE 495
Query: 358 TNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-----KSPAKSPNPSTPRGKKRKALPA 412
E E + P PA E +K A KSPA++ +P K + +
Sbjct: 496 GGEEETKSP---------PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 413 SETPKA-----AESETPGKSPEKKPKIKEEAVK--EKSPSLGKKDAR-----------QT 454
E K+ A+S KSPEK+ VK EK+ S K++A+ ++
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 455 PKKPEAKFFTTPSKSVRKASHTPK--KWPKKPKVP 487
P K EAK V++ + +P K P+K K P
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Score = 42.7 bits (99), Expect = 7e-04
Identities = 53/188 (28%), Positives = 78/188 (41%), Gaps = 24/188 (12%)
Query: 311 KTASVLSKDDVAPESGDTTVKKPESK----KEQTPEHGKKKRGRGKAQVKATNESEDEIP 366
K SV + V E V+K E + +EQT E + + T E E E
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET--------QVTEEVTEEEEKEAK 479
Query: 367 QLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKA-AESETPG 425
+ GK+ E+ E + KSP P +K P E K+ AE+++P
Sbjct: 480 E--EEGKEEEGGEEEEAEGGEEETKSP---PAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534
Query: 426 KSPEKKPKIKEEAVKEKSPSLGKKDARQTP--KKPEAKFFTTPS--KSVRKASHTPKKWP 481
K K P + K KSP+ K++A+ P K PE + +P+ KS KA K+
Sbjct: 535 KEEAKSPAEVKSPEKAKSPA--KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 482 KKPKVPQS 489
K P +S
Sbjct: 593 KSPAEAKS 600
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 60.1 bits (144), Expect = 4e-09
Identities = 54/209 (25%), Positives = 99/209 (47%), Gaps = 37/209 (17%)
Query: 281 NKKKKEARRKRRERNFE---KQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKK 337
+ +K+E ++ E E ++ E K++++ K+ V +K+++ D V+KPE K
Sbjct: 558 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV---ADAKVEKPEKAK 614
Query: 338 EQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSP 397
P+ +++G+ K+ E + + P VP K+P EK KSP
Sbjct: 615 SPVPKSPVEEKGKSPVP-KSPVEEKGKSP--VP---KSPVEEK-------------GKSP 655
Query: 398 NPSTPRGKKRKALPASETPKAAESETP-GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPK 456
P +P +K K+ P S++P ++++P KSP ++ K K E K + +K+ ++ PK
Sbjct: 656 VPKSPVEEKGKS-PVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 714
Query: 457 KPEAKFFTTPSKSVRKASHTPKKWPKKPK 485
+ + V K PK P+K K
Sbjct: 715 E----------EKVEKKEEKPKDVPEKKK 733
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 27/233 (11%)
Query: 280 LNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE----S 335
+ ++KKEA ++ E +++E K+ + TA + +++ E + ++ E +
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 543
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHA-------- 387
K +Q E G +K G + K E E+ + G++ A E+ ++++ +
Sbjct: 544 KSDQAEEGGSEKEGSSE---KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600
Query: 388 ------TGKKSPAKSPNPSTPRGKKRKA----LPASETPKAAESETPGKSPEKKPKIKEE 437
K AKSP P +P +K K+ P E K+ ++P + K P + +
Sbjct: 601 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP-VPKS 659
Query: 438 AVKEKSPS-LGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQS 489
V+EK S + K + K P K +KS + +K ++ +V ++
Sbjct: 660 PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 712
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/276 (23%), Positives = 104/276 (37%), Gaps = 53/276 (19%)
Query: 261 LPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDD 320
L + FV E TK + +EA E KE KK+ + ++ +++
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 321 VAPESGDTTVKKPESKKE-----------------------QTPEHGKKKRGRGKAQVKA 357
VA + PE K+E Q E G +K G + K
Sbjct: 506 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE---KE 562
Query: 358 TNESEDEIPQLVPIGKKTPANEKVEIQKHA--------------TGKKSPAKSPNPSTPR 403
E E+ + G++ A E+ ++++ + K AKSP P +P
Sbjct: 563 EGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 622
Query: 404 GKKRKA-LPASETPKAAESETP-------GKSPEKKPKIKEEAVKEKSPSLGKKDARQ-T 454
+K K+ +P S + +S P GKSP K ++E+ S S ++ A+
Sbjct: 623 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 682
Query: 455 PKKP--EAKFFTTPSKSVRKASHTP--KKWPKKPKV 486
PK P EAK K +K K+ PK+ KV
Sbjct: 683 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 718
Score = 34.3 bits (77), Expect = 0.26
Identities = 35/164 (21%), Positives = 69/164 (42%), Gaps = 13/164 (7%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDT-TVK 331
E K +++KE + +E EK++E+ K + +K S + ++ VA T +VK
Sbjct: 695 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754
Query: 332 ---KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHAT 388
+ E+K+E P +K++ + + + E D+ G K E + +
Sbjct: 755 VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK-------GAKGSRKEDIAVNGEVE 807
Query: 389 GKKSPAKSPNPSTPRGKKRKALPAS--ETPKAAESETPGKSPEK 430
GK+ + ++ K + + + A E + KS EK
Sbjct: 808 GKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 851
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 60.1 bits (144), Expect = 4e-09
Identities = 54/209 (25%), Positives = 99/209 (47%), Gaps = 37/209 (17%)
Query: 281 NKKKKEARRKRRERNFE---KQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKK 337
+ +K+E ++ E E ++ E K++++ K+ V +K+++ D V+KPE K
Sbjct: 182 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV---ADAKVEKPEKAK 238
Query: 338 EQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSP 397
P+ +++G+ K+ E + + P VP K+P EK KSP
Sbjct: 239 SPVPKSPVEEKGKSPVP-KSPVEEKGKSP--VP---KSPVEEK-------------GKSP 279
Query: 398 NPSTPRGKKRKALPASETPKAAESETP-GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPK 456
P +P +K K+ P S++P ++++P KSP ++ K K E K + +K+ ++ PK
Sbjct: 280 VPKSPVEEKGKS-PVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 338
Query: 457 KPEAKFFTTPSKSVRKASHTPKKWPKKPK 485
+ + V K PK P+K K
Sbjct: 339 E----------EKVEKKEEKPKDVPEKKK 357
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 27/233 (11%)
Query: 280 LNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE----S 335
+ ++KKEA ++ E +++E K+ + TA + +++ E + ++ E +
Sbjct: 108 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 167
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHA-------- 387
K +Q E G +K G + K E E+ + G++ A E+ ++++ +
Sbjct: 168 KSDQAEEGGSEKEGSSE---KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 224
Query: 388 ------TGKKSPAKSPNPSTPRGKKRKA----LPASETPKAAESETPGKSPEKKPKIKEE 437
K AKSP P +P +K K+ P E K+ ++P + K P + +
Sbjct: 225 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP-VPKS 283
Query: 438 AVKEKSPS-LGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQS 489
V+EK S + K + K P K +KS + +K ++ +V ++
Sbjct: 284 PVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 336
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/276 (23%), Positives = 104/276 (37%), Gaps = 53/276 (19%)
Query: 261 LPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDD 320
L + FV E TK + +EA E KE KK+ + ++ +++
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 321 VAPESGDTTVKKPESKKE-----------------------QTPEHGKKKRGRGKAQVKA 357
VA + PE K+E Q E G +K G + K
Sbjct: 130 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE---KE 186
Query: 358 TNESEDEIPQLVPIGKKTPANEKVEIQKHA--------------TGKKSPAKSPNPSTPR 403
E E+ + G++ A E+ ++++ + K AKSP P +P
Sbjct: 187 EGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 246
Query: 404 GKKRKA-LPASETPKAAESETP-------GKSPEKKPKIKEEAVKEKSPSLGKKDARQ-T 454
+K K+ +P S + +S P GKSP K ++E+ S S ++ A+
Sbjct: 247 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 455 PKKP--EAKFFTTPSKSVRKASHTP--KKWPKKPKV 486
PK P EAK K +K K+ PK+ KV
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 342
Score = 34.3 bits (77), Expect = 0.26
Identities = 35/164 (21%), Positives = 69/164 (42%), Gaps = 13/164 (7%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDT-TVK 331
E K +++KE + +E EK++E+ K + +K S + ++ VA T +VK
Sbjct: 319 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378
Query: 332 ---KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHAT 388
+ E+K+E P +K++ + + + E D+ G K E + +
Sbjct: 379 VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK-------GAKGSRKEDIAVNGEVE 431
Query: 389 GKKSPAKSPNPSTPRGKKRKALPAS--ETPKAAESETPGKSPEK 430
GK+ + ++ K + + + A E + KS EK
Sbjct: 432 GKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 475
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 58.5 bits (140), Expect = 1e-08
Identities = 52/213 (24%), Positives = 98/213 (46%), Gaps = 13/213 (6%)
Query: 245 WESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKK 304
WE VK K + F +E K+ L +K +E E + +K++ +KK
Sbjct: 41 WEEVKKQL--ENKKTGSKALAEFEEKMNENWKKEL--EKSREKLLSGNESSSKKRERKKK 96
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
+++++ +++S S D + S D+ + +K+Q KKK K+ +T+ESE E
Sbjct: 97 RKKKSCRSSSSSSSSDSSSSSSDSE----DEEKKQGKRRKKKKNRSYKSSQSSTHESESE 152
Query: 365 IPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETP 424
+ V KK + ++ E +K +S +K S P K + +SE+ + +
Sbjct: 153 SKESVK--KKKKSKDETEKEKDV---RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
Query: 425 GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKK 457
K ++ + +E VK+K KK +++ KK
Sbjct: 208 KKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 58.2 bits (139), Expect = 2e-08
Identities = 69/269 (25%), Positives = 98/269 (36%), Gaps = 50/269 (18%)
Query: 266 SFVSNWDEATKRSL-LNKKKKEARRKRRERNFEKQKERKKKRQQARKTASV--LSKDDVA 322
S N D + + SL +NK+ ++ N + + K+K A++T S+ S D+A
Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 323 PES---------GDTTVKKPE------------------SKKEQTPEHGKKKRGRGKAQV 355
P S +TT K P + KE TP K K
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 356 KATNESEDEIP---------QLVPIGKKTPANEKVEIQKHATGKKSPA--KSPNPSTPRG 404
T +S P + P K PA + T K +P K P P+TP+
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 405 KKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFT 464
PA TPK TP + PK KE +P+ K+ A PKKP
Sbjct: 309 ------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 362
Query: 465 TPSKSVRK---ASHTPKKWPKKPKVPQST 490
P+ + K + T + P PK P T
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391
Score = 46.6 bits (109), Expect = 5e-05
Identities = 64/233 (27%), Positives = 85/233 (36%), Gaps = 23/233 (9%)
Query: 275 TKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE 334
T +S K+ A +E KE + + S E TT KKP
Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 335 --SKKEQTPEHGKKKRGRG-KAQVKATNESEDEIP-QLVPIGKKTPANEKVEIQKHATGK 390
+ KE P K+ K T E P + P K PA + + T
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTP 369
Query: 391 KSPA----KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPK------IKEEAV- 439
K PA K P+P+TP+ ++ T + T KS PK KE A
Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429
Query: 440 --KEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
KE +P+ KK A TPK+P TTP + + T K P PK P T
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAP---TTPKEPA--PTTTKKPAPTTPKEPAPT 477
Score = 43.9 bits (102), Expect = 3e-04
Identities = 49/175 (28%), Positives = 66/175 (37%), Gaps = 20/175 (11%)
Query: 324 ESGDTTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIP-QLVPIGKKTPANEK 380
E TT K+P + KE P K K T +S P + P K PA
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430
Query: 381 VEIQKHATGKK---SPAKSPNPSTPR--GKKRKALPASETPKAAESETPGKSPEKKPKIK 435
+ T KK + K P P+TP+ PA TPK TP ++ PK
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-- 488
Query: 436 EEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
+ +P+ +K A TP+KP TTP + P P P+ P T
Sbjct: 489 -----KLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPT--PTTPEEPAPT 533
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 6/157 (3%)
Query: 328 TTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQK 385
TT K+P + KE P K + T + +L P K P + +
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 685
Query: 386 HATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPS 445
T K++ +P P K+ A ETP SE + K+P ++ E +P
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745
Query: 446 LG----KKDARQTPKKPEAKFFTTPSKSVRKASHTPK 478
L K +PK+P TP+ + + + T K
Sbjct: 746 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/185 (26%), Positives = 63/185 (34%), Gaps = 27/185 (14%)
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-- 390
PE TPE + A + + P K PA + T K
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578
Query: 391 -KSPAKSPNPSTPRGKKRKAL---------------PASETPKAAESETPGKSPEKKPKI 434
+ K P P+TP+ K L PA TPK TP + PK
Sbjct: 579 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 638
Query: 435 KEEAV-KEKSPSLGKKDARQTPKKPEAKFFT-------TPSKSVRKASHTPKKW-PKKPK 485
K +P+ K+ A TPKKP K T + S + A TPK+ P PK
Sbjct: 639 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 698
Query: 486 VPQST 490
P T
Sbjct: 699 EPAPT 703
Score = 38.5 bits (88), Expect = 0.014
Identities = 36/183 (19%), Positives = 61/183 (33%), Gaps = 9/183 (4%)
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
K+ ++ A +K+ + P+ TP+ + A +
Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651
Query: 365 IPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETP 424
+ + P K PA +++ + + P P+TP+ A TPK TP
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE------TAPTTPKEPAPTTP 705
Query: 425 GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKP 484
K P+ E S K+ K P+ +TP S + PK+P
Sbjct: 706 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPELSAEPTPKALENSPKEP 762
Query: 485 KVP 487
VP
Sbjct: 763 GVP 765
Score = 37.4 bits (85), Expect = 0.031
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 23/165 (13%)
Query: 324 ESGDTTVK--KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKV 381
E+ TT K P + KE P KK + A + + P K A
Sbjct: 569 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628
Query: 382 EIQKHATGKKSPA------------KSPNPSTPRGKKRKALPASETPKAAESETPGKSPE 429
+ + T K PA K P P+TP+ K L A T K S T K
Sbjct: 629 K-EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAP 686
Query: 430 KKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKAS 474
P KE +P+ K+ A TPKKP TP + + S
Sbjct: 687 TTP-------KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Score = 33.1 bits (74), Expect = 0.59
Identities = 39/195 (20%), Positives = 71/195 (36%), Gaps = 14/195 (7%)
Query: 284 KKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEH 343
K A K K K ++ + +T + K + E+ TT K ESK T
Sbjct: 768 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITATTTQ 825
Query: 344 GKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-KSPAKSPNPSTP 402
+ K T + V KKT ++ + T K K A + +TP
Sbjct: 826 VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 885
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKF 462
+ +K KA + T K P+ P++++ + +P+ K + P ++
Sbjct: 886 KPQK--------PTKAPKKPTSTKKPKTMPRVRK---PKTTPTPRKMTSTMPELNPTSRI 934
Query: 463 FTTPSKSVRKASHTP 477
++ + + TP
Sbjct: 935 AEAMLQTTTRPNQTP 949
Score = 32.7 bits (73), Expect = 0.77
Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 8/162 (4%)
Query: 324 ESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP----IGKKTPANE 379
E G T K P + K + K K + ++ T E+ P++ +KT ++
Sbjct: 761 EPGVPTTKTPAATKPEMTTTAKDKTT--ERDLRTTPETTTAAPKMTKETATTTEKTTESK 818
Query: 380 KVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAV 439
T + +P T A + T K + PE+ K K+ A
Sbjct: 819 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 878
Query: 440 KEKSPSLGKKDARQTPKKPEA--KFFTTPSKSVRKASHTPKK 479
K+ + + + PKKP + K T P K + TP+K
Sbjct: 879 NSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 920
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 58.2 bits (139), Expect = 2e-08
Identities = 69/269 (25%), Positives = 98/269 (36%), Gaps = 50/269 (18%)
Query: 266 SFVSNWDEATKRSL-LNKKKKEARRKRRERNFEKQKERKKKRQQARKTASV--LSKDDVA 322
S N D + + SL +NK+ ++ N + + K+K A++T S+ S D+A
Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 323 PES---------GDTTVKKPE------------------SKKEQTPEHGKKKRGRGKAQV 355
P S +TT K P + KE TP K K
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 356 KATNESEDEIP---------QLVPIGKKTPANEKVEIQKHATGKKSPA--KSPNPSTPRG 404
T +S P + P K PA + T K +P K P P+TP+
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 405 KKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFT 464
PA TPK TP + PK KE +P+ K+ A PKKP
Sbjct: 350 ------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 403
Query: 465 TPSKSVRK---ASHTPKKWPKKPKVPQST 490
P+ + K + T + P PK P T
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432
Score = 46.6 bits (109), Expect = 5e-05
Identities = 64/233 (27%), Positives = 85/233 (36%), Gaps = 23/233 (9%)
Query: 275 TKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE 334
T +S K+ A +E KE + + S E TT KKP
Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 335 --SKKEQTPEHGKKKRGRG-KAQVKATNESEDEIP-QLVPIGKKTPANEKVEIQKHATGK 390
+ KE P K+ K T E P + P K PA + + T
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTP 410
Query: 391 KSPA----KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPK------IKEEAV- 439
K PA K P+P+TP+ ++ T + T KS PK KE A
Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470
Query: 440 --KEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
KE +P+ KK A TPK+P TTP + + T K P PK P T
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAP---TTPKEPA--PTTTKKPAPTTPKEPAPT 518
Score = 43.9 bits (102), Expect = 3e-04
Identities = 49/175 (28%), Positives = 66/175 (37%), Gaps = 20/175 (11%)
Query: 324 ESGDTTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIP-QLVPIGKKTPANEK 380
E TT K+P + KE P K K T +S P + P K PA
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471
Query: 381 VEIQKHATGKK---SPAKSPNPSTPR--GKKRKALPASETPKAAESETPGKSPEKKPKIK 435
+ T KK + K P P+TP+ PA TPK TP ++ PK
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-- 529
Query: 436 EEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
+ +P+ +K A TP+KP TTP + P P P+ P T
Sbjct: 530 -----KLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPT--PTTPEEPAPT 574
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 6/157 (3%)
Query: 328 TTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQK 385
TT K+P + KE P K + T + +L P K P + +
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 726
Query: 386 HATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPS 445
T K++ +P P K+ A ETP SE + K+P ++ E +P
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786
Query: 446 LG----KKDARQTPKKPEAKFFTTPSKSVRKASHTPK 478
L K +PK+P TP+ + + + T K
Sbjct: 787 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/185 (26%), Positives = 63/185 (34%), Gaps = 27/185 (14%)
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-- 390
PE TPE + A + + P K PA + T K
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619
Query: 391 -KSPAKSPNPSTPRGKKRKAL---------------PASETPKAAESETPGKSPEKKPKI 434
+ K P P+TP+ K L PA TPK TP + PK
Sbjct: 620 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 679
Query: 435 KEEAV-KEKSPSLGKKDARQTPKKPEAKFFT-------TPSKSVRKASHTPKKW-PKKPK 485
K +P+ K+ A TPKKP K T + S + A TPK+ P PK
Sbjct: 680 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 739
Query: 486 VPQST 490
P T
Sbjct: 740 EPAPT 744
Score = 38.5 bits (88), Expect = 0.014
Identities = 36/183 (19%), Positives = 61/183 (33%), Gaps = 9/183 (4%)
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
K+ ++ A +K+ + P+ TP+ + A +
Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692
Query: 365 IPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETP 424
+ + P K PA +++ + + P P+TP+ A TPK TP
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE------TAPTTPKEPAPTTP 746
Query: 425 GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKP 484
K P+ E S K+ K P+ +TP S + PK+P
Sbjct: 747 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPELSAEPTPKALENSPKEP 803
Query: 485 KVP 487
VP
Sbjct: 804 GVP 806
Score = 37.4 bits (85), Expect = 0.031
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 23/165 (13%)
Query: 324 ESGDTTVK--KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKV 381
E+ TT K P + KE P KK + A + + P K A
Sbjct: 610 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669
Query: 382 EIQKHATGKKSPA------------KSPNPSTPRGKKRKALPASETPKAAESETPGKSPE 429
+ + T K PA K P P+TP+ K L A T K S T K
Sbjct: 670 K-EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAP 727
Query: 430 KKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKAS 474
P KE +P+ K+ A TPKKP TP + + S
Sbjct: 728 TTP-------KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Score = 33.1 bits (74), Expect = 0.59
Identities = 39/195 (20%), Positives = 71/195 (36%), Gaps = 14/195 (7%)
Query: 284 KKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEH 343
K A K K K ++ + +T + K + E+ TT K ESK T
Sbjct: 809 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITATTTQ 866
Query: 344 GKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-KSPAKSPNPSTP 402
+ K T + V KKT ++ + T K K A + +TP
Sbjct: 867 VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 926
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKF 462
+ +K KA + T K P+ P++++ + +P+ K + P ++
Sbjct: 927 KPQK--------PTKAPKKPTSTKKPKTMPRVRK---PKTTPTPRKMTSTMPELNPTSRI 975
Query: 463 FTTPSKSVRKASHTP 477
++ + + TP
Sbjct: 976 AEAMLQTTTRPNQTP 990
Score = 32.7 bits (73), Expect = 0.77
Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 8/162 (4%)
Query: 324 ESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP----IGKKTPANE 379
E G T K P + K + K K + ++ T E+ P++ +KT ++
Sbjct: 802 EPGVPTTKTPAATKPEMTTTAKDKTT--ERDLRTTPETTTAAPKMTKETATTTEKTTESK 859
Query: 380 KVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAV 439
T + +P T A + T K + PE+ K K+ A
Sbjct: 860 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 919
Query: 440 KEKSPSLGKKDARQTPKKPEA--KFFTTPSKSVRKASHTPKK 479
K+ + + + PKKP + K T P K + TP+K
Sbjct: 920 NSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 961
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 58.2 bits (139), Expect = 2e-08
Identities = 69/269 (25%), Positives = 98/269 (36%), Gaps = 50/269 (18%)
Query: 266 SFVSNWDEATKRSL-LNKKKKEARRKRRERNFEKQKERKKKRQQARKTASV--LSKDDVA 322
S N D + + SL +NK+ ++ N + + K+K A++T S+ S D+A
Sbjct: 222 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 281
Query: 323 PES---------GDTTVKKPE------------------SKKEQTPEHGKKKRGRGKAQV 355
P S +TT K P + KE TP K K
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 356 KATNESEDEIP---------QLVPIGKKTPANEKVEIQKHATGKKSPA--KSPNPSTPRG 404
T +S P + P K PA + T K +P K P P+TP+
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 405 KKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFT 464
PA TPK TP + PK KE +P+ K+ A PKKP
Sbjct: 402 ------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 455
Query: 465 TPSKSVRK---ASHTPKKWPKKPKVPQST 490
P+ + K + T + P PK P T
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPKEPAPT 484
Score = 46.6 bits (109), Expect = 5e-05
Identities = 64/233 (27%), Positives = 85/233 (36%), Gaps = 23/233 (9%)
Query: 275 TKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE 334
T +S K+ A +E KE + + S E TT KKP
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 335 --SKKEQTPEHGKKKRGRG-KAQVKATNESEDEIP-QLVPIGKKTPANEKVEIQKHATGK 390
+ KE P K+ K T E P + P K PA + + T
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTP 462
Query: 391 KSPA----KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPK------IKEEAV- 439
K PA K P+P+TP+ ++ T + T KS PK KE A
Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522
Query: 440 --KEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
KE +P+ KK A TPK+P TTP + + T K P PK P T
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEPAP---TTPKEPA--PTTTKKPAPTTPKEPAPT 570
Score = 43.9 bits (102), Expect = 3e-04
Identities = 49/175 (28%), Positives = 66/175 (37%), Gaps = 20/175 (11%)
Query: 324 ESGDTTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIP-QLVPIGKKTPANEK 380
E TT K+P + KE P K K T +S P + P K PA
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523
Query: 381 VEIQKHATGKK---SPAKSPNPSTPR--GKKRKALPASETPKAAESETPGKSPEKKPKIK 435
+ T KK + K P P+TP+ PA TPK TP ++ PK
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-- 581
Query: 436 EEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
+ +P+ +K A TP+KP TTP + P P P+ P T
Sbjct: 582 -----KLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPT--PTTPEEPAPT 626
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 6/157 (3%)
Query: 328 TTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQK 385
TT K+P + KE P K + T + +L P K P + +
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778
Query: 386 HATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPS 445
T K++ +P P K+ A ETP SE + K+P ++ E +P
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838
Query: 446 LG----KKDARQTPKKPEAKFFTTPSKSVRKASHTPK 478
L K +PK+P TP+ + + + T K
Sbjct: 839 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 875
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/185 (26%), Positives = 63/185 (34%), Gaps = 27/185 (14%)
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-- 390
PE TPE + A + + P K PA + T K
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671
Query: 391 -KSPAKSPNPSTPRGKKRKAL---------------PASETPKAAESETPGKSPEKKPKI 434
+ K P P+TP+ K L PA TPK TP + PK
Sbjct: 672 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 731
Query: 435 KEEAV-KEKSPSLGKKDARQTPKKPEAKFFT-------TPSKSVRKASHTPKKW-PKKPK 485
K +P+ K+ A TPKKP K T + S + A TPK+ P PK
Sbjct: 732 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 791
Query: 486 VPQST 490
P T
Sbjct: 792 EPAPT 796
Score = 38.5 bits (88), Expect = 0.014
Identities = 36/183 (19%), Positives = 61/183 (33%), Gaps = 9/183 (4%)
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
K+ ++ A +K+ + P+ TP+ + A +
Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 744
Query: 365 IPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETP 424
+ + P K PA +++ + + P P+TP+ A TPK TP
Sbjct: 745 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE------TAPTTPKEPAPTTP 798
Query: 425 GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKP 484
K P+ E S K+ K P+ +TP S + PK+P
Sbjct: 799 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPELSAEPTPKALENSPKEP 855
Query: 485 KVP 487
VP
Sbjct: 856 GVP 858
Score = 37.4 bits (85), Expect = 0.031
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 23/165 (13%)
Query: 324 ESGDTTVK--KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKV 381
E+ TT K P + KE P KK + A + + P K A
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721
Query: 382 EIQKHATGKKSPA------------KSPNPSTPRGKKRKALPASETPKAAESETPGKSPE 429
+ + T K PA K P P+TP+ K L A T K S T K
Sbjct: 722 K-EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAP 779
Query: 430 KKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKAS 474
P KE +P+ K+ A TPKKP TP + + S
Sbjct: 780 TTP-------KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 817
Score = 33.1 bits (74), Expect = 0.59
Identities = 39/195 (20%), Positives = 71/195 (36%), Gaps = 14/195 (7%)
Query: 284 KKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEH 343
K A K K K ++ + +T + K + E+ TT K ESK T
Sbjct: 861 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITATTTQ 918
Query: 344 GKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-KSPAKSPNPSTP 402
+ K T + V KKT ++ + T K K A + +TP
Sbjct: 919 VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 978
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKF 462
+ +K KA + T K P+ P++++ + +P+ K + P ++
Sbjct: 979 KPQK--------PTKAPKKPTSTKKPKTMPRVRK---PKTTPTPRKMTSTMPELNPTSRI 1027
Query: 463 FTTPSKSVRKASHTP 477
++ + + TP
Sbjct: 1028 AEAMLQTTTRPNQTP 1042
Score = 32.7 bits (73), Expect = 0.77
Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 8/162 (4%)
Query: 324 ESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP----IGKKTPANE 379
E G T K P + K + K K + ++ T E+ P++ +KT ++
Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDKTT--ERDLRTTPETTTAAPKMTKETATTTEKTTESK 911
Query: 380 KVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAV 439
T + +P T A + T K + PE+ K K+ A
Sbjct: 912 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 971
Query: 440 KEKSPSLGKKDARQTPKKPEA--KFFTTPSKSVRKASHTPKK 479
K+ + + + PKKP + K T P K + TP+K
Sbjct: 972 NSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1013
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 58.2 bits (139), Expect = 2e-08
Identities = 69/269 (25%), Positives = 98/269 (36%), Gaps = 50/269 (18%)
Query: 266 SFVSNWDEATKRSL-LNKKKKEARRKRRERNFEKQKERKKKRQQARKTASV--LSKDDVA 322
S N D + + SL +NK+ ++ N + + K+K A++T S+ S D+A
Sbjct: 263 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 322
Query: 323 PES---------GDTTVKKPE------------------SKKEQTPEHGKKKRGRGKAQV 355
P S +TT K P + KE TP K K
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 356 KATNESEDEIP---------QLVPIGKKTPANEKVEIQKHATGKKSPA--KSPNPSTPRG 404
T +S P + P K PA + T K +P K P P+TP+
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 405 KKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFT 464
PA TPK TP + PK KE +P+ K+ A PKKP
Sbjct: 443 ------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496
Query: 465 TPSKSVRK---ASHTPKKWPKKPKVPQST 490
P+ + K + T + P PK P T
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPT 525
Score = 46.6 bits (109), Expect = 5e-05
Identities = 64/233 (27%), Positives = 85/233 (36%), Gaps = 23/233 (9%)
Query: 275 TKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE 334
T +S K+ A +E KE + + S E TT KKP
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 335 --SKKEQTPEHGKKKRGRG-KAQVKATNESEDEIP-QLVPIGKKTPANEKVEIQKHATGK 390
+ KE P K+ K T E P + P K PA + + T
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTP 503
Query: 391 KSPA----KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPK------IKEEAV- 439
K PA K P+P+TP+ ++ T + T KS PK KE A
Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563
Query: 440 --KEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
KE +P+ KK A TPK+P TTP + + T K P PK P T
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEPAP---TTPKEPA--PTTTKKPAPTTPKEPAPT 611
Score = 43.9 bits (102), Expect = 3e-04
Identities = 49/175 (28%), Positives = 66/175 (37%), Gaps = 20/175 (11%)
Query: 324 ESGDTTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIP-QLVPIGKKTPANEK 380
E TT K+P + KE P K K T +S P + P K PA
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564
Query: 381 VEIQKHATGKK---SPAKSPNPSTPR--GKKRKALPASETPKAAESETPGKSPEKKPKIK 435
+ T KK + K P P+TP+ PA TPK TP ++ PK
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-- 622
Query: 436 EEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
+ +P+ +K A TP+KP TTP + P P P+ P T
Sbjct: 623 -----KLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPT--PTTPEEPAPT 667
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 6/157 (3%)
Query: 328 TTVKKPE--SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQK 385
TT K+P + KE P K + T + +L P K P + +
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819
Query: 386 HATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPS 445
T K++ +P P K+ A ETP SE + K+P ++ E +P
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879
Query: 446 LG----KKDARQTPKKPEAKFFTTPSKSVRKASHTPK 478
L K +PK+P TP+ + + + T K
Sbjct: 880 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 916
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/185 (26%), Positives = 63/185 (34%), Gaps = 27/185 (14%)
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-- 390
PE TPE + A + + P K PA + T K
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712
Query: 391 -KSPAKSPNPSTPRGKKRKAL---------------PASETPKAAESETPGKSPEKKPKI 434
+ K P P+TP+ K L PA TPK TP + PK
Sbjct: 713 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 772
Query: 435 KEEAV-KEKSPSLGKKDARQTPKKPEAKFFT-------TPSKSVRKASHTPKKW-PKKPK 485
K +P+ K+ A TPKKP K T + S + A TPK+ P PK
Sbjct: 773 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 832
Query: 486 VPQST 490
P T
Sbjct: 833 EPAPT 837
Score = 38.5 bits (88), Expect = 0.014
Identities = 36/183 (19%), Positives = 61/183 (33%), Gaps = 9/183 (4%)
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
K+ ++ A +K+ + P+ TP+ + A +
Sbjct: 726 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 785
Query: 365 IPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETP 424
+ + P K PA +++ + + P P+TP+ A TPK TP
Sbjct: 786 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE------TAPTTPKEPAPTTP 839
Query: 425 GKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKP 484
K P+ E S K+ K P+ +TP S + PK+P
Sbjct: 840 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPELSAEPTPKALENSPKEP 896
Query: 485 KVP 487
VP
Sbjct: 897 GVP 899
Score = 37.4 bits (85), Expect = 0.031
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 23/165 (13%)
Query: 324 ESGDTTVK--KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKV 381
E+ TT K P + KE P KK + A + + P K A
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762
Query: 382 EIQKHATGKKSPA------------KSPNPSTPRGKKRKALPASETPKAAESETPGKSPE 429
+ + T K PA K P P+TP+ K L A T K S T K
Sbjct: 763 K-EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAP 820
Query: 430 KKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKAS 474
P KE +P+ K+ A TPKKP TP + + S
Sbjct: 821 TTP-------KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 858
Score = 33.1 bits (74), Expect = 0.59
Identities = 39/195 (20%), Positives = 71/195 (36%), Gaps = 14/195 (7%)
Query: 284 KKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEH 343
K A K K K ++ + +T + K + E+ TT K ESK T
Sbjct: 902 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITATTTQ 959
Query: 344 GKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK-KSPAKSPNPSTP 402
+ K T + V KKT ++ + T K K A + +TP
Sbjct: 960 VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 1019
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKF 462
+ +K KA + T K P+ P++++ + +P+ K + P ++
Sbjct: 1020 KPQK--------PTKAPKKPTSTKKPKTMPRVRK---PKTTPTPRKMTSTMPELNPTSRI 1068
Query: 463 FTTPSKSVRKASHTP 477
++ + + TP
Sbjct: 1069 AEAMLQTTTRPNQTP 1083
Score = 32.7 bits (73), Expect = 0.77
Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 8/162 (4%)
Query: 324 ESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP----IGKKTPANE 379
E G T K P + K + K K + ++ T E+ P++ +KT ++
Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDKTT--ERDLRTTPETTTAAPKMTKETATTTEKTTESK 952
Query: 380 KVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAV 439
T + +P T A + T K + PE+ K K+ A
Sbjct: 953 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 1012
Query: 440 KEKSPSLGKKDARQTPKKPEA--KFFTTPSKSVRKASHTPKK 479
K+ + + + PKKP + K T P K + TP+K
Sbjct: 1013 NSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1054
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 58.2 bits (139), Expect = 2e-08
Identities = 61/232 (26%), Positives = 92/232 (39%), Gaps = 30/232 (12%)
Query: 228 ENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNW-----------DEATK 276
E VTK + P K ES + + VK +K S E +
Sbjct: 563 EETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAE 622
Query: 277 RSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESK 336
+ + K K A+ K ++ K K KK ++ + V K+D P + KK E K
Sbjct: 623 KQATDVKPKAAKEKTVKKE-TKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVK 681
Query: 337 KEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKS 396
KE E K+++ K +VK ++ + K+ EK E++K K K
Sbjct: 682 KEVKKEIKKEEKKEPKKEVKKETPPKE-------VKKEVKKEEKKEVKKEEKEPKKEIK- 733
Query: 397 PNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK 448
P+ K+ + P SE K P K PK KEE+VK+ S + GK
Sbjct: 734 ---KLPKDAKKSSTPLSEAKK------PAALKPKVPK-KEESVKKDSVAAGK 775
Score = 57.8 bits (138), Expect = 2e-08
Identities = 58/235 (24%), Positives = 108/235 (45%), Gaps = 22/235 (9%)
Query: 257 KSAALPIFSSFV--SNWDEATKRSLLNKKKKEARRKRRERNF-EKQKERKKKRQQARKTA 313
K AA P+ S V + +E + + +N +K + + +E+ +K K K + + +
Sbjct: 546 KPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEK 605
Query: 314 SVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGK 373
V SK++ +P + K+ K P+ K+K + + +VK ++ E++ + K
Sbjct: 606 EVPSKEEPSPVKAEVAEKQATDVK---PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAK 662
Query: 374 KTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPK 433
K +K I+K KK K + +++K E K + ETP K +K+ K
Sbjct: 663 K---EDKTPIKKEEKPKKEEVKKEVKKEIKKEEKK-----EPKKEVKKETPPKEVKKEVK 714
Query: 434 IKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQ 488
+E+ +K KK+ ++ PK +AK +TP +K + KPKVP+
Sbjct: 715 KEEKKEVKKEEKEPKKEIKKLPK--DAKKSSTPLSEAKKPAAL------KPKVPK 761
Score = 55.5 bits (132), Expect = 1e-07
Identities = 53/209 (25%), Positives = 93/209 (44%), Gaps = 28/209 (13%)
Query: 275 TKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE 334
+K ++ KK K + + + EK+ K++ + + DV P++ K E
Sbjct: 582 SKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKE 641
Query: 335 SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPA 394
+K + PE K+++ + K +V + ED+ P KK +K E++K K
Sbjct: 642 TKVK--PEDKKEEKEKPKKEVA---KKEDKTPI-----KKEEKPKKEEVKKEV---KKEI 688
Query: 395 KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQT 454
K P+ + +K P E K + E+K ++K+E EK P KK+ ++
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKK-------EEKKEVKKE---EKEP---KKEIKKL 735
Query: 455 PKKPEAKFFTTPSKSVRKASHTPKKWPKK 483
PK +AK +TP +K + K PKK
Sbjct: 736 PK--DAKKSSTPLSEAKKPAALKPKVPKK 762
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 22/193 (11%)
Query: 298 KQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKA 357
K K+R R+ + A L V ES + T PE K E K + K VK
Sbjct: 534 KLKQRADSRESLKPAAKPLPSKSVRKESKEET---PEVTKVNHVEKPPKVESKEKVMVKK 590
Query: 358 TNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPK 417
PI K E + T K+ P+K PS + + + PK
Sbjct: 591 DK----------PI--------KTETKPSVTEKEVPSKE-EPSPVKAEVAEKQATDVKPK 631
Query: 418 AAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTP 477
AA+ +T K + KP+ K+E ++ + KK+ + KK E K V+K
Sbjct: 632 AAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKE 691
Query: 478 KKWPKKPKVPQST 490
+K K +V + T
Sbjct: 692 EKKEPKKEVKKET 704
Score = 35.4 bits (80), Expect = 0.12
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 23/140 (16%)
Query: 359 NESEDEIPQLVPIGKKTPAN--EKVEIQKH--------ATGKKSPAKSPNPSTPRGKKRK 408
N +E I L P G T N E +E KH AT K + P P + K ++
Sbjct: 479 NPAEKIIRVLFP-GNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQ 537
Query: 409 ALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFT---- 464
+ E+ K A P KS K+ KE++P + K + + P K E+K
Sbjct: 538 RADSRESLKPAAKPLPSKSVRKES-------KEETPEVTKVNHVEKPPKVESKEKVMVKK 590
Query: 465 -TPSKSVRKASHTPKKWPKK 483
P K+ K S T K+ P K
Sbjct: 591 DKPIKTETKPSVTEKEVPSK 610
Score = 33.5 bits (75), Expect = 0.45
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 12/104 (11%)
Query: 391 KSPAKSPNP-----STPRGKK--RKALPASETPKAAESETPGKSPEKKPKIKEE---AVK 440
KSP+ SP+P TP G++ +L +E +AE+E SPE ++ EE + +
Sbjct: 1255 KSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPE 1314
Query: 441 EKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKP 484
+K+ + T ++ +P+ K+SH P + +KP
Sbjct: 1315 DKTLEVVSPSQSVTGSAGHTPYYQSPTD--EKSSHLPTEVIEKP 1356
Score = 32.0 bits (71), Expect = 1.3
Identities = 30/130 (23%), Positives = 56/130 (43%), Gaps = 8/130 (6%)
Query: 366 PQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPK-AAESETP 424
P+ + I + K ++++ KK K+ + S + K+ P + +PK A E+
Sbjct: 2222 PEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESS 2281
Query: 425 GK-----SPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTP-- 477
K SP+KK +++ A +P + + K+ + + SKS + A+ P
Sbjct: 2282 DKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGT 2341
Query: 478 KKWPKKPKVP 487
K K VP
Sbjct: 2342 TKTTKSSAVP 2351
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/207 (24%), Positives = 91/207 (43%), Gaps = 16/207 (7%)
Query: 275 TKRSLLNKKKKEARRKR-RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKP 333
T+R KK++ R KR RER E+++ER KK ++ RK + + + + K+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 334 ESKKEQTPEHGKKKR---GRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK 390
K+ + + KKKR RG+ + K E ++ ++ ++ E ++ K
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKE---------RERENKQRRERKRKKRRK 140
Query: 391 KSPAKSPNPSTPRGK---KRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLG 447
K K RGK KRK E K E + E++ K + E KE+
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
Query: 448 KKDARQTPKKPEAKFFTTPSKSVRKAS 474
KK R+ +K + + + + +R+++
Sbjct: 201 KKKERKKDRKTDRQTDSQVFRPLRESA 227
Score = 50.4 bits (119), Expect = 4e-06
Identities = 48/210 (22%), Positives = 90/210 (42%), Gaps = 32/210 (15%)
Query: 276 KRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPES 335
+ S K+++E +++RER E+++ER KK ++ RK E G +K +
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKR----------ERGKERERKRKE 81
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAK 395
+++Q E +K+R + K + K + G++ +K ++ K+ +
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQR--------GRRERKKKKERKERERENKQRRER 133
Query: 396 SPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTP 455
R K+RK E + E GK K+ K K+E +EK +K+ ++
Sbjct: 134 K------RKKRRKKKRRKERKREKER---GKRERKRKKRKKEE-REKKRERNRKERKKER 183
Query: 456 KKPEAKFFTTPSKSVRKASHTPKKWPKKPK 485
++ E + K RK KK KK +
Sbjct: 184 ERKERR----ERKKERKKERRKKKERKKDR 209
Score = 36.6 bits (83), Expect = 0.053
Identities = 18/43 (41%), Positives = 31/43 (72%), Gaps = 2/43 (4%)
Query: 272 DEATKRSLLNKKKKEARRKRRERNFEKQKERKKK--RQQARKT 312
++ +R+ +KK+ R++RRER E++KER+KK R++ RKT
Sbjct: 169 EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 54.3 bits (129), Expect = 2e-07
Identities = 52/240 (21%), Positives = 96/240 (40%), Gaps = 24/240 (10%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK 332
+ T++ ++K + + +E+ K+K R+K++ + + T + PE+ ++
Sbjct: 146 DKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQ 205
Query: 333 PESKKEQTPEHGKKKRGRGKAQ--VKATNESEDEIPQLVPIGKKTPANEKVEIQKH---- 386
++K + E KK +G Q VK T E+ + K+ EK + KH
Sbjct: 206 KKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKD 265
Query: 387 ------------ATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKI 434
G P +SP P ++ + P +P E E K EK K+
Sbjct: 266 QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEK--KV 323
Query: 435 KEEAVKEKSPSLGKKDARQT----PKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
E K++ + KK ++T KK K T +V+ A+ K +K + + T
Sbjct: 324 TSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKT 383
Score = 47.0 bits (110), Expect = 4e-05
Identities = 44/172 (25%), Positives = 76/172 (44%), Gaps = 8/172 (4%)
Query: 285 KEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHG 344
K+A ++E K E++ +++++ KT+S+L D P G K P S KE+ PE
Sbjct: 439 KKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILK--DKEPIKGKEE-KVPASLKEKEPETK 495
Query: 345 KKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRG 404
K ++ KA E + + PQL ++ P + + K A +K + P
Sbjct: 496 KDEK-----MSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEK 550
Query: 405 KKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPK 456
P + K ++ T K+ + KP K E + + PS+ + TPK
Sbjct: 551 TVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPK 602
Score = 46.6 bits (109), Expect = 5e-05
Identities = 62/273 (22%), Positives = 110/273 (40%), Gaps = 28/273 (10%)
Query: 240 KLPEKWESV---KLLFVKTEKS----AALPIFSSFVSNWDEATKRSLLNKKKKEARRKR- 291
K P+K SV K + KTE++ A+ I + +E T +++ + +KE K
Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTS 467
Query: 292 ---RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKP---ESKKEQTPEHGK 345
+++ K KE K K KD+ ++G KP + KKE+ PE
Sbjct: 468 SILKDKEPIKGKEEKVPASLKEKEPET-KKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQI 526
Query: 346 KKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGK 405
KK + K +D + + P + ++ K T +K+ P T + +
Sbjct: 527 KKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKP---TKKAE 583
Query: 406 KRKALPAS-------ETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKP 458
R+ P S TPK T +S +KK +I E+ KEK+ ++ + + +K
Sbjct: 584 HREREPPSIKTDKPKPTPKGTSEVT--ESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
Query: 459 EAKFF-TTPSKSVRKASHTPKKWPKKPKVPQST 490
+ T ++ + S + P K + T
Sbjct: 642 SLQLHNVTKAEKPARVSKDVEDVPASKKAKEGT 674
Score = 42.7 bits (99), Expect = 7e-04
Identities = 73/311 (23%), Positives = 119/311 (38%), Gaps = 72/311 (23%)
Query: 239 EKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARR-----KRRE 293
EK+ +K + K +K A S +E TK+ + K+++ ++ K +
Sbjct: 188 EKIEKKEKPETKTLAKEQKKAKTAEKS------EEKTKKEVKGGKQEKVKQTAAKVKEVQ 241
Query: 294 RNFEKQKERKKKRQQA-------------RKTASVLSKDDVAPESGDTTVKKPESKKEQ- 339
+ K KE++ K + A R + D+ P G + P EQ
Sbjct: 242 KTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKP--GQSPAIPPPLPTEQA 299
Query: 340 ------TPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSP 393
+P +K+ + KA+ K T+E++ + + I KK+ ++++K GK S
Sbjct: 300 SRPTPASPALEEKEGEKKKAEKKVTSETKKKEKE--DIKKKSEKETAIDVEKKEPGKASE 357
Query: 394 AKS------------PNPSTPRGKKRKALPASETPKAAESET------PGKSPE------ 429
K + KK K E PK + E P KSP+
Sbjct: 358 TKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVP 417
Query: 430 --KKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRK------ASHTPKKWP 481
K+ K K E KE+ ++ K A P K E K T + +RK +S K P
Sbjct: 418 SDKQVKAKTERAKEEIGAVSIKKA--VPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEP 475
Query: 482 ---KKPKVPQS 489
K+ KVP S
Sbjct: 476 IKGKEEKVPAS 486
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 52.8 bits (125), Expect = 7e-07
Identities = 55/221 (24%), Positives = 94/221 (42%), Gaps = 36/221 (16%)
Query: 272 DEATKRSLLNKKKKEARR-----KRRERNFEKQKERKKKRQQARK--TASVLSKDDVAPE 324
D S L + KK++++ K +E + +K+ KK ++ A K ++ S+D+
Sbjct: 126 DTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGA 185
Query: 325 SGDTTVKKPESKK---------------EQTPEHGKKKRGRGKAQ------VKATNESED 363
D K +S K E+ + GKK +GK VKA + ++
Sbjct: 186 KKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDE 245
Query: 364 EIPQLVPIG--KKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPAS-ETPKAAE 420
+ + G K + EI+K KK P+ + + S KK A+ + K A+
Sbjct: 246 DGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAK 305
Query: 421 SETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAK 461
+T +S + K K+ A K+ KKDA++ KK E K
Sbjct: 306 KDTEKESADSKKDAKKNAKKD-----AKKDAKKNAKKDEKK 341
Score = 47.4 bits (111), Expect = 3e-05
Identities = 56/196 (28%), Positives = 74/196 (37%), Gaps = 20/196 (10%)
Query: 306 RQQARKTASVLSKDDVAPESG----DTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNES 361
R+Q K + D A E G D T +K + E + GKK +GK K E
Sbjct: 95 RRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEK 154
Query: 362 EDEIPQLVPIGKKTPANEK---VEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKA 418
D GKK K E + G K K + +GK E
Sbjct: 155 LDAKKDSKK-GKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGT 213
Query: 419 AESETPGKSPEKKPK---IKEEAVK--EKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKA 473
+ GK KK K I+ +AVK EK GKKDA + + +AK +K ++K
Sbjct: 214 EKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAK---KDAKEIKKG 270
Query: 474 SHTPKKWPKKPKVPQS 489
KK KKP S
Sbjct: 271 ----KKDKKKPSSTDS 282
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 52.4 bits (124), Expect = 9e-07
Identities = 54/211 (25%), Positives = 87/211 (41%), Gaps = 33/211 (15%)
Query: 257 KSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVL 316
K LP+ +V +E R L K K RRK+R KE++KK ++ +
Sbjct: 714 KVPGLPMSDQYVKLEEERRHRQKLEKDK---RRKKR-------KEKEKKGKRRHSSLPTE 763
Query: 317 SKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQL-VPIGKKT 375
S +D+AP ++ + E+ PE+ K + D L + + K
Sbjct: 764 SDEDIAP------AQQVDIVTEEMPENALPSDEDDK-------DPNDPYRALDIDLDKPL 810
Query: 376 PANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESE-------TPGKSP 428
+EK+ IQKH + S KSP P +K+ P + K E E K
Sbjct: 811 ADSEKLPIQKHRNTETS--KSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKK 868
Query: 429 EKKPKIKEEAVKEKSPSLGKKDARQTPKKPE 459
KPK K+ +++ + GKK +++ P E
Sbjct: 869 SPKPKKKKHRKEKEERTKGKKKSKKQPPGSE 899
Score = 35.8 bits (81), Expect = 0.091
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 27/99 (27%)
Query: 283 KKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE 342
KKKE + K +ER+ EK+KE++KK+ K KK K+++
Sbjct: 845 KKKEKKHKEKERDKEKKKEKEKKKSPKPK-------------------KKKHRKEKEERT 885
Query: 343 HGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKV 381
GKKK K Q + E+ E P+ P E++
Sbjct: 886 KGKKK---SKKQPPGSEEAAGE-----PVQNGAPEEEQL 916
Score = 30.0 bits (66), Expect = 5.0
Identities = 17/78 (21%), Positives = 36/78 (46%)
Query: 281 NKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQT 340
+K+KK+ + K++ +K+K RK+K ++ + + + E+ V+ ++EQ
Sbjct: 857 DKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQL 916
Query: 341 PEHGKKKRGRGKAQVKAT 358
P + VK T
Sbjct: 917 PPESSYSLLAENSYVKMT 934
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/197 (27%), Positives = 78/197 (39%), Gaps = 21/197 (10%)
Query: 297 EKQKERKKKRQQARKTASVLSKDDVAPESGDTT--VKKPESKKEQTPEHGKKKRGRGKAQ 354
EK + ++ R K VL +V PE KKPE+ + PE K+ K
Sbjct: 10480 EKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVP 10539
Query: 355 VKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAK--SPNPSTPRGKKRKALPA 412
V + P++ P K P K + + + P K SP P P K + +P
Sbjct: 10540 VPPPKK-----PEVPPT--KVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPK-EVVPE 10591
Query: 413 SETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTP--KKPEAKFFTTPSKSV 470
+ P AA + P +P K P+ +E V EK + + P K PE P K V
Sbjct: 10592 KKVP-AAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKV 10650
Query: 471 RKASHTPKKWPKKPKVP 487
P+ P KP+ P
Sbjct: 10651 ------PEAIPPKPESP 10661
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 15/173 (8%)
Query: 320 DVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANE 379
+V PE KKPE + PE KK K V +E P++ ++ E
Sbjct: 10755 EVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEE 10814
Query: 380 KVEIQKHA---TGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPG-KSPEKKPKIK 435
++ ++ ++ + P P+ P K K +P + P + E P K PE + I+
Sbjct: 10815 EIAPEEEKPVPVAEEEEPEVPPPAVPEEPK-KIIPEKKVPVIKKPEAPPPKEPEPEKVIE 10873
Query: 436 EEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQ 488
+ +K + P P K + K K++ K KK P+KP+VP+
Sbjct: 10874 KPKLKPRPPP-----PPPAPPKEDVKEKIFQLKAIPK-----KKVPEKPQVPE 10916
Score = 47.0 bits (110), Expect = 4e-05
Identities = 60/219 (27%), Positives = 81/219 (36%), Gaps = 32/219 (14%)
Query: 276 KRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPES 335
K+ + KK K+ E K E K+ +K V+ K AP + K PE
Sbjct: 10698 KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPA-----KVPEV 10752
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAK 395
KE PE KK K +V P VP K P E +K A A+
Sbjct: 10753 PKEVVPE--KKVAVPKKPEVP---------PAKVPEVPKKPVLE----EKPAVPVPERAE 10797
Query: 396 SPNPSTPR-----GKKRKALPASETP-KAAESETPGKSPEKKPKIKEEAVKEKSPSLGKK 449
SP P + + P E P AE E P P P+ ++ + EK + KK
Sbjct: 10798 SPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKK 10857
Query: 450 DARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQ 488
PK+PE P K + K P+ P P P+
Sbjct: 10858 PEAPPPKEPE------PEKVIEKPKLKPRPPPPPPAPPK 10890
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/237 (25%), Positives = 89/237 (37%), Gaps = 42/237 (17%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKT-ASVLSKDDVAPESGDTTVK 331
E K ++ KK EA + E + E K+ +K A+ K +V P VK
Sbjct: 10555 EVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP------VK 10608
Query: 332 KPESKKEQTPEHGKKKRGRGKAQVKATNESE--------DEIPQLVPIGKKTPANEKVEI 383
PE+ KE PE K +V T E ++P+ +P ++P E E
Sbjct: 10609 VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE 10668
Query: 384 QKHATGKKSPAK---SPNPSTPRG----------KKRKALPASETPKAAESETPGKSPEK 430
+ ++ PA+ P P+ P +K+ A ++ P P K
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKK--------APAVVAKKPELPPVK 10720
Query: 431 KPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVP 487
P++ +E V EK L PKKPEA P PKKP+VP
Sbjct: 10721 VPEVPKEVVPEKKVPL------VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP 10771
Score = 43.9 bits (102), Expect = 3e-04
Identities = 52/181 (28%), Positives = 68/181 (37%), Gaps = 25/181 (13%)
Query: 321 VAPESGDTTVKKPESKKEQTPEHGK-------KKRGRGKAQVKATNESEDEIPQLVPIGK 373
+ PE +KKPE+ + PE K K R + +++I QL I K
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905
Query: 374 KTPAN-----EKVEIQ--KHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGK 426
K EKVE+ K G+K K P K+ L S K E E P
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLK-SVLRKRPEEEEPKV 10964
Query: 427 SPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKV 486
P+K K+K+ AV E P PK E T +K RK K KP +
Sbjct: 10965 EPKKLEKVKKPAVPEPPP----------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAI 11014
Query: 487 P 487
P
Sbjct: 11015 P 11015
Score = 40.4 bits (93), Expect = 0.004
Identities = 59/224 (26%), Positives = 85/224 (37%), Gaps = 44/224 (19%)
Query: 303 KKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE----------HGKKKRGRGK 352
K KR A + V K+ P V+ PE KE PE H ++ +
Sbjct: 9873 KPKRVVAEEKVPVPRKEVAPP------VRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEE 9926
Query: 353 AQVKATNE---SEDEIPQLVPIG-----KKTPANEKVEIQKHATGKKSPAKSPN-PSTPR 403
+ E +E+E+ ++P+ +K EK + + PAK P P P
Sbjct: 9927 EEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPE 9986
Query: 404 GKKRKALPASETPKAAESETPGKSPEKKPKI------KEEAVKEKSPSLGKKDARQ---- 453
K +P E P A+ K P + K+ K EA K P + KK +
Sbjct: 9987 EKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVP 10046
Query: 454 --TPKK---PEAKFFTTPSKSV---RKASHTPKK-WPKKPKVPQ 488
PKK P AK P K + +K + PKK PKVP+
Sbjct: 10047 VPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPK 10090
Score = 40.4 bits (93), Expect = 0.004
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 6/203 (2%)
Query: 292 RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK--PESKKEQTPEHGKKKRG 349
+E+ F+ + KKK + + + + G+ V+K PE K E E K
Sbjct: 10894 KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953
Query: 350 RGKAQVKATNESEDEIPQLV-PIGKKTPANEKVEIQKHATGKKSPAKSPNPS-TPRGKKR 407
R + + + ++ ++ P + P + VE + T K K P P+ P K
Sbjct: 10954 RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA 11013
Query: 408 KALPASETPKAAESETPG-KSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTP 466
LPA E E+E K P +P+ A P +GKK + PK+ AK P
Sbjct: 11014 IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAK-PKGP 11072
Query: 467 SKSVRKASHTPKKWPKKPKVPQS 489
K V K + +P + ++ P S
Sbjct: 11073 IKGVPKKTPSPIEAERRKLRPGS 11095
Score = 39.3 bits (90), Expect = 0.008
Identities = 54/218 (24%), Positives = 87/218 (39%), Gaps = 30/218 (13%)
Query: 276 KRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPES 335
K+ ++ K +K +RR E+ Q K V K + P+ T + E
Sbjct: 9182 KKPVIEKIEKTSRRMEEEK------------VQVTKVPEVSKK--IVPQKPSRTPVQEEV 9227
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP-IGKKTPANEKVEIQKHATGKKSPA 394
+ + P KK + ++ + +E+E+ VP + K+ EK+ + + P
Sbjct: 9228 IEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPK 9287
Query: 395 KSPNPSTPRGKKRKALPASETPKAAESETPGKSPE--KKPKIKEEA---VKEKSPSLGKK 449
P P ++ +P PK E P K PE KKP +E+ V +K P+ K
Sbjct: 9288 VPELPEKPAPEEVAPVPI---PKKVEPPAP-KVPEVPKKPVPEEKKPVPVPKKEPAAPPK 9343
Query: 450 DARQTPKK--PEAKFFTTPSKSVRKASHTPKKWPKKPK 485
+ PKK PE K P +K P K P+ K
Sbjct: 9344 -VPEVPKKPVPEEKI---PVPVAKKKEAPPAKVPEVQK 9377
Score = 37.7 bits (86), Expect = 0.024
Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 33/183 (18%)
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
K++ K + K++ P KK E K+ P+ + V+ T E E+E
Sbjct: 10191 KKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV------LPVEVTEEPEEE 10244
Query: 365 IPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETP 424
I ++ P+ E+VE + +P + P +KA+P + TP + E P
Sbjct: 10245 PISEEEIPEEPPSIEEVE-------EVAPPRVPEVI------KKAVPEAPTPVPKKVEAP 10291
Query: 425 -----GKSPEKK---PKIKEEAVKEKSPSLGKKDARQ---TPKK---PEAKFFTTPSKSV 470
K PE+K P K+EA K P + KK + PKK P AK T + V
Sbjct: 10292 PAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKV 10351
Query: 471 RKA 473
A
Sbjct: 10352 SVA 10354
Score = 36.2 bits (82), Expect = 0.070
Identities = 58/243 (23%), Positives = 92/243 (37%), Gaps = 17/243 (6%)
Query: 248 VKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQ 307
VK+ V T+K F S+ +E ++ +K+ ++ K+ E K
Sbjct: 9230 VKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVP 9289
Query: 308 QARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQ 367
+ + + ++VAP V+ P K PE KK K V + P+
Sbjct: 9290 ELPEKPA---PEEVAPVPIPKKVEPPAPK---VPEVPKKPVPEEKKPVPVPKKEPAAPPK 9343
Query: 368 LVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRK---ALPASETPKAAESETP 424
+ + KK EK+ + + PAK P + K E+P A E P
Sbjct: 9344 VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIP 9403
Query: 425 GKS-PEKKPKI--KEEAV--KEKSPSLGKK---DARQTPKKPEAKFFTTPSKSVRKASHT 476
K PE++ + KEE V K P+L KK + + P AK P V K +
Sbjct: 9404 KKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVV 9463
Query: 477 PKK 479
+K
Sbjct: 9464 EEK 9466
Score = 35.4 bits (80), Expect = 0.12
Identities = 52/251 (20%), Positives = 98/251 (39%), Gaps = 15/251 (5%)
Query: 236 GLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERN 295
G E+ + + + L + K K + + + ++ L+++ ++ KR +
Sbjct: 582 GAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQ 641
Query: 296 FEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTP-EHGKKKRGRGKAQ 354
++K RK+ + A T +V + E+ T + +++EQ HGK G+
Sbjct: 642 ITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEA 701
Query: 355 VKATNESEDEIPQLVPIGKKTPANEKVEIQKHAT---GKK---SPAKSPNPSTPRGKKRK 408
V + D+ P + P + + + T G K S AK P +
Sbjct: 702 VATVVAAVDQARVREP---REPGHLEESYAQQTTLEYGYKERISAAKVAEPPQRPASEPH 758
Query: 409 ALPASETPKA--AESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPE--AKFFT 464
+P + P+ A SET K+ ++K +K K+ L + K+P + FT
Sbjct: 759 VVPKAVKPRVIQAPSETHIKTTDQKGMHISSQIK-KTTDLTTERLVHVDKRPRTASPHFT 817
Query: 465 TPSKSVRKASH 475
SV K H
Sbjct: 818 VSKISVPKTEH 828
Score = 34.3 bits (77), Expect = 0.26
Identities = 53/238 (22%), Positives = 84/238 (35%), Gaps = 27/238 (11%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK 332
E KR++ +K + + KR E K E +K+ + K + K + P T ++
Sbjct: 9666 EEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIME- 9724
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVE-----IQKHA 387
E ++ T E R + + E + P + E E ++H
Sbjct: 9725 -EKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHE 9783
Query: 388 TGKKSPAK----SPNPSTPRGKKRKALPASETPKAAESE------------TPGKSPEKK 431
P K P P P K KA PA KA E P K PE+
Sbjct: 9784 EYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEP 9843
Query: 432 PKIKEEAVK----EKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPK 485
K+ EE ++ ++ + A + P KP+ RK P + P+ PK
Sbjct: 9844 KKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPK 9901
Score = 34.3 bits (77), Expect = 0.26
Identities = 40/182 (21%), Positives = 78/182 (42%), Gaps = 23/182 (12%)
Query: 311 KTASVLSKDDVAPESGDTTVKKPESK--KEQTPEHGKKKRGRGKAQVKATNESED--EIP 366
K V K+ V P G T +++ S +++ + + +A+V+ E E+ E+
Sbjct: 10328 KKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387
Query: 367 QLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGK 426
+ G+ E +++++H ++ + K + + E + E P K
Sbjct: 10388 EYFEEGEFHEVEEFIKLEQHRVEEEHRVE---------KVHRVIEVFEAEEVEVFEKP-K 10437
Query: 427 SPEKKPKIKEEAVKEKSPSLGKKDARQTPKK-PEAKFFTTPSKSVRKASHTPKKWPKKPK 485
+P K P+I E+ + K P + P+K P AK P K V + + P++P+
Sbjct: 10438 APPKGPEISEKIIPPKKP-----PTKVVPRKEPPAKVPEVPKKIVVEEK---VRVPEEPR 10489
Query: 486 VP 487
VP
Sbjct: 10490 VP 10491
Score = 33.1 bits (74), Expect = 0.59
Identities = 48/222 (21%), Positives = 84/222 (37%), Gaps = 28/222 (12%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK 332
E K+ + KK K E K ER + Q K ++K + P++ +
Sbjct: 9610 EEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKA-----RV 9664
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIP-QLVPIGKKTPANEKVEIQKHATGKK 391
PE K PE + +K + E+E P ++ K+ EKV I+
Sbjct: 9665 PEEPKRAVPE---------EKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIE------- 9708
Query: 392 SPAKSPNP---STPRGKKRKALPASETPKAAESETPGKSPEK--KPKIKEEAVKEKSPSL 446
+P + P P T +K +A E + + E + E+ + +E E+
Sbjct: 9709 APKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQY 9768
Query: 447 GKKDARQTPKKPE-AKFFTTPSKSVRKASHTPKKWPKKPKVP 487
+ + R+ + E ++ T P K + + P KPK P
Sbjct: 9769 EEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAP 9810
Score = 30.0 bits (66), Expect = 5.0
Identities = 42/187 (22%), Positives = 67/187 (35%), Gaps = 32/187 (17%)
Query: 330 VKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIG-KKTPANEKVEIQKHAT 388
V + E E+ + +++ G + + E+E ++ + P VE + H
Sbjct: 9484 VTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHII 9543
Query: 389 GKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK 448
K+ A+ P T R +K+ L + P E P K PE KI E K+ + K
Sbjct: 9544 SKRVEAE-PAEVTERQEKKIVLKP-KIPAKIEEPPPAKVPEAPKKIVPE--KKVPAPVPK 9599
Query: 449 KDARQTPKKPEAKFFTTPSKSVRK---------------------------ASHTPKKWP 481
K+ PK PE P K V + T K+ P
Sbjct: 9600 KEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAP 9659
Query: 482 KKPKVPQ 488
K +VP+
Sbjct: 9660 PKARVPE 9666
>gi|15431288 ribosomal protein L10a [Homo sapiens]
Length = 217
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 2/126 (1%)
Query: 130 ISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVPVSVNLLSKN 189
+ ++ LKK K+ + +L +D FL + + +P ++G + K P S+ ++N
Sbjct: 85 MDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFP-SLLTHNEN 143
Query: 190 LSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEKLPEKWESVK 249
+ ++++ + T+ K C A+ +GHV M + ++ NI L L + W++V+
Sbjct: 144 MVAKVDE-VKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVR 202
Query: 250 LLFVKT 255
L++K+
Sbjct: 203 ALYIKS 208
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/283 (19%), Positives = 108/283 (38%), Gaps = 57/283 (20%)
Query: 214 IRIGHVGMQIEHIIENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDE 273
+ + H+ + ++H+ +N A + VK L +E + S VS+W
Sbjct: 96 LTLQHLPLTVDHLKQNNTA-------------KLVKQLSKSSEDEELRKLASVLVSDWMA 142
Query: 274 ATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKP 333
+ + ++ ++KR++ E K + + + + + A E+ + +KP
Sbjct: 143 VIRSQSSTQPAEKDKKKRKD-------EGKSRTTLPERPLTEVKAETRAEEAPEKKREKP 195
Query: 334 ESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPA---NEKVEIQKHATGK 390
+S + P H K + + E E P LVP+ K ++K ++ +
Sbjct: 196 KSLRTTAPSHAKFR----------STGLELETPSLVPVKKNASTVVVSDKYNLKPIPLKR 245
Query: 391 KSPAKSPNPSTPRGKKRKALPASETPKAAE-----------------------SETPGKS 427
+S +P +TP +K K P + TP A + + PG
Sbjct: 246 QSNVAAPGDATPPAEK-KYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPVPGIK 304
Query: 428 PEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSV 470
+KK K+ + SP GK + KP + PS+++
Sbjct: 305 IKKKKKVLSPTAAKPSPFEGKTSTEPSTAKPSSPEPAPPSEAM 347
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/206 (21%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK 332
++ RS K+K+ R K +E+ K+K+R+K+R++ ++ + E G +
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER-------EKEKERGKNKDRD 418
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKS 392
E +K++ + K + + + + + E E Q K EK ++ +K
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ-----DKEKEREKDRSKEIDEKRKK 473
Query: 393 PAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSP-SLGKKDA 451
KS P R++ +S + S + +SP IK ++ + SP S KKD
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 452 RQTPKKP--EAKFFTTPSKSVRKASH 475
++ ++ + S S+RK+S+
Sbjct: 534 KREKERDHISERRERERSTSMRKSSN 559
Score = 42.7 bits (99), Expect = 7e-04
Identities = 45/201 (22%), Positives = 80/201 (39%), Gaps = 29/201 (14%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEK------QKERKKKRQQARKTASVLSKDDVAPESG 326
E K NK + + R K RE++ EK +KE +K R + ++ K+ S
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Query: 327 DTTVKKPESKKEQTP--EHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQ 384
+ K+ + KK +TP + +R R ++ + S ++P K
Sbjct: 466 EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS--------SSRSPRTSK---- 513
Query: 385 KHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEK-- 442
T K+ ++SP+P + K +K E +E +S + + KEK
Sbjct: 514 ---TIKRKSSRSPSPRSRNKKDKKR--EKERDHISERRERERSTSMRKSSNDRDGKEKLE 568
Query: 443 --SPSLGKKDARQTPKKPEAK 461
S SL +K+ + P +K
Sbjct: 569 KNSTSLKEKEHNKEPDSSVSK 589
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/206 (21%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK 332
++ RS K+K+ R K +E+ K+K+R+K+R++ ++ + E G +
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER-------EKEKERGKNKDRD 302
Query: 333 PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKS 392
E +K++ + K + + + + + E E Q K EK ++ +K
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ-----DKEKEREKDRSKEIDEKRKK 357
Query: 393 PAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSP-SLGKKDA 451
KS P R++ +S + S + +SP IK ++ + SP S KKD
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 452 RQTPKKP--EAKFFTTPSKSVRKASH 475
++ ++ + S S+RK+S+
Sbjct: 418 KREKERDHISERRERERSTSMRKSSN 443
Score = 42.7 bits (99), Expect = 7e-04
Identities = 45/201 (22%), Positives = 80/201 (39%), Gaps = 29/201 (14%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEK------QKERKKKRQQARKTASVLSKDDVAPESG 326
E K NK + + R K RE++ EK +KE +K R + ++ K+ S
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Query: 327 DTTVKKPESKKEQTP--EHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQ 384
+ K+ + KK +TP + +R R ++ + S ++P K
Sbjct: 350 EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS--------SSRSPRTSK---- 397
Query: 385 KHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEK-- 442
T K+ ++SP+P + K +K E +E +S + + KEK
Sbjct: 398 ---TIKRKSSRSPSPRSRNKKDKKR--EKERDHISERRERERSTSMRKSSNDRDGKEKLE 452
Query: 443 --SPSLGKKDARQTPKKPEAK 461
S SL +K+ + P +K
Sbjct: 453 KNSTSLKEKEHNKEPDSSVSK 473
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 21/181 (11%)
Query: 276 KRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPES 335
K+ K+++E +++RRE+ ++ +E++K++++ +K SK+ G +K E
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE------GKERERKEER 139
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAK 395
K+E+ E +KK R K + + + + + EK E +K K+ +
Sbjct: 140 KREERKERERKKEEREKERERKERKKRE----------RKQVGEKEEERKEKERKERKKR 189
Query: 396 SPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTP 455
N K+RK + + + E K KK + K+ + GK++ ++
Sbjct: 190 ERN-----RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Query: 456 K 456
K
Sbjct: 245 K 245
Score = 49.7 bits (117), Expect = 6e-06
Identities = 47/233 (20%), Positives = 100/233 (42%), Gaps = 20/233 (8%)
Query: 230 IVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARR 289
+ A++ + KL + + V + K P + S + + + KK++E+ R
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHIS--KPCTQPGWQSEIREREREIETRKEGKKERESER 59
Query: 290 KRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRG 349
K+ R EK+K R++++++ R+ K + E + ++ E + ++ E K+K+
Sbjct: 60 KKERREREKRK-REREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKK 118
Query: 350 RGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKA 409
K + + + E ++ ++ K E +K KK + + ++RK
Sbjct: 119 EKKERGRTSKEGKE---------RERKEERKREERKERERKKEERE-------KERERKE 162
Query: 410 LPASETPKAAESETPGKSPEKKPKIKEEA-VKEKSPSLGKKDARQTPKKPEAK 461
E + E E K E+K + K E KE+ +K+ R+ K+ + K
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/181 (20%), Positives = 82/181 (45%), Gaps = 6/181 (3%)
Query: 282 KKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTP 341
K+++E RKR EK+ ERKK+ ++ +K K++ E + KK + ++ +T
Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRR--EKENKEGEEKEKRKKKEKKERGRTS 127
Query: 342 EHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPST 401
+ GK++ + + + + E E + + K+ E+ + ++ G+K +
Sbjct: 128 KEGKERERKEERKREERKERERKKEERE---KERERKERKKRERKQVGEKEEERKEKERK 184
Query: 402 PRGKK-RKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEA 460
R K+ R + + E K +KK + K+E K++ + +K+ + +K
Sbjct: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Query: 461 K 461
K
Sbjct: 245 K 245
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/182 (21%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 276 KRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPES 335
+ S K+++E +++RER E+++ER KK ++ + + E + K
Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN----KEGE 110
Query: 336 KKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAK 395
+KE+ + KK+RGR + K E+ + +K +K E +K K+ +
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKRE----ERKERERKKEEREKERERKERKKR 166
Query: 396 SPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTP 455
+ ++RK E K E + E++ K + E KE+ +K RQ
Sbjct: 167 ERKQVGEKEEERKEKERKER-KKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Query: 456 KK 457
++
Sbjct: 226 RQ 227
Score = 47.0 bits (110), Expect = 4e-05
Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 273 EATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKK 332
E +R ++K+E R++R + E++KER++K ++ R+ V K++ E KK
Sbjct: 129 EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188
Query: 333 PE-SKKEQTPEHGKKKRGRGKAQVKATNESEDE 364
E ++KE+ E +K+R K + K E + E
Sbjct: 189 RERNRKERKKERERKERRERKKERKKKEERKKE 221
Score = 30.4 bits (67), Expect = 3.8
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKF 462
R ++R+ E K ESE K ++ K K E KE+ GKK+ + KK E +
Sbjct: 39 REREREIETRKEGKKERESERK-KERREREKRKREREKERKRERGKKEKKGERKKEERER 97
Query: 463 FTTPSKSVRKASHTPKKWPKKPK 485
+ K +K KK K
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEK 120
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 50.4 bits (119), Expect = 4e-06
Identities = 42/175 (24%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Query: 283 KKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE 342
KK+E RR R R+ ++ R + R++ S + + K P ++ + E
Sbjct: 241 KKEEKRRHSRSRS-RSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299
Query: 343 HGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTP 402
G++ R K + K + E + + P T A + ++S + + +P P
Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYST-ARRSRSASRERRRRRSRSGTRSPKKP 358
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKK 457
R KRK L S +P+ + E +KK K KE + E+ S KK + +K
Sbjct: 359 RSPKRK-LSRSPSPRRHKKE------KKKDKDKERSRDERERSTSKKKKSKDKEK 406
Score = 45.8 bits (107), Expect = 9e-05
Identities = 37/189 (19%), Positives = 82/189 (43%), Gaps = 11/189 (5%)
Query: 300 KERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATN 359
+E K+ ++A+ S + D E + + S++ +TP + +R R +++ ++ +
Sbjct: 220 EEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHS 279
Query: 360 ESEDEIPQLVPI---------GKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKAL 410
+S P G+++ + K +K +K +K+P S ++ ++
Sbjct: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS- 338
Query: 411 PASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSV 470
AS + S + +SP+K K + + SP KK+ ++ K ++ S S
Sbjct: 339 -ASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSK 397
Query: 471 RKASHTPKK 479
+K S +K
Sbjct: 398 KKKSKDKEK 406
Score = 34.7 bits (78), Expect = 0.20
Identities = 36/182 (19%), Positives = 71/182 (39%), Gaps = 37/182 (20%)
Query: 276 KRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVA--------PESGD 327
+RS ++ + +R + R+ +K+ + KK+ + K+ S + A SG
Sbjct: 293 RRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT 352
Query: 328 TTVKKPESKKEQ-----TPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVE 382
+ KKP S K + +P KK++ + K + ++ +E E
Sbjct: 353 RSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERE-------------------- 392
Query: 383 IQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEK 442
+T KK +K R K + + + E G EK+ K +++ ++
Sbjct: 393 ---RSTSKKKKSKDKEKDRER-KSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETG 448
Query: 443 SP 444
SP
Sbjct: 449 SP 450
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.4 bits (119), Expect = 4e-06
Identities = 53/226 (23%), Positives = 96/226 (42%), Gaps = 19/226 (8%)
Query: 238 SEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRS------LLNKKKKEARRKR 291
SE + +S + V ++S +FS + DE R L+ K K+E +
Sbjct: 425 SESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRE 484
Query: 292 RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKK---KR 348
R++ +K+K RK++++Q K ++++ + + + + EQ + K+ KR
Sbjct: 485 RQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKR 544
Query: 349 GRG----KAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRG 404
G+ K Q K+ +E+ D + GK+ P EIQK +TG P S + G
Sbjct: 545 GKEITGVKRQSKSEHETSDAKKSVEDRGKRCPT---PEIQKKSTG-DVPHTSVTGDSGSG 600
Query: 405 K--KRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK 448
K K K P S + E+ +E + +S +G+
Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGR 646
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.4 bits (119), Expect = 4e-06
Identities = 53/226 (23%), Positives = 96/226 (42%), Gaps = 19/226 (8%)
Query: 238 SEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRS------LLNKKKKEARRKR 291
SE + +S + V ++S +FS + DE R L+ K K+E +
Sbjct: 425 SESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRE 484
Query: 292 RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKK---KR 348
R++ +K+K RK++++Q K ++++ + + + + EQ + K+ KR
Sbjct: 485 RQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKR 544
Query: 349 GRG----KAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRG 404
G+ K Q K+ +E+ D + GK+ P EIQK +TG P S + G
Sbjct: 545 GKEITGVKRQSKSEHETSDAKKSVEDRGKRCPT---PEIQKKSTG-DVPHTSVTGDSGSG 600
Query: 405 K--KRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK 448
K K K P S + E+ +E + +S +G+
Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGR 646
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.4 bits (119), Expect = 4e-06
Identities = 53/226 (23%), Positives = 96/226 (42%), Gaps = 19/226 (8%)
Query: 238 SEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRS------LLNKKKKEARRKR 291
SE + +S + V ++S +FS + DE R L+ K K+E +
Sbjct: 425 SESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRE 484
Query: 292 RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKK---KR 348
R++ +K+K RK++++Q K ++++ + + + + EQ + K+ KR
Sbjct: 485 RQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKR 544
Query: 349 GRG----KAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRG 404
G+ K Q K+ +E+ D + GK+ P EIQK +TG P S + G
Sbjct: 545 GKEITGVKRQSKSEHETSDAKKSVEDRGKRCPT---PEIQKKSTG-DVPHTSVTGDSGSG 600
Query: 405 K--KRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK 448
K K K P S + E+ +E + +S +G+
Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGR 646
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 50.4 bits (119), Expect = 4e-06
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 18/146 (12%)
Query: 318 KDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKT-P 376
+ D ES DT +KK E+ ++QT E KK++ + + E E P+ + KK P
Sbjct: 6 RSDAGLES-DTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEP 64
Query: 377 ANEKVEIQKHATGKKSPAKSPNPSTPRGK----------------KRKALPASETPKAAE 420
+ + K KK S N +P+ K K K + +E P E
Sbjct: 65 SEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEE 124
Query: 421 SETPGKSPEKKPKIKEEAVKEKSPSL 446
+ P KK K +EKSP L
Sbjct: 125 IDAPKPKKMKKEKEMNGETREKSPKL 150
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 31/159 (19%)
Query: 283 KKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE 342
KK E RK+ E EK+K+ K K + +++A E K + KK+ P
Sbjct: 18 KKGETLRKQTE---EKEKKEKPKSDKT---------EEIAEEEETVFPKAKQVKKKAEPS 65
Query: 343 HGKKKRGRGKAQVKATNESEDEI-PQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPS- 400
+ K K S+++I P+ + KK E +E + ++ K K+ PS
Sbjct: 66 EVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKK---KEPIEKKVVSSKTKKVTKNEEPSE 122
Query: 401 ----TPRGKKRKALPASETPKAAESETPGKSPEKKPKIK 435
P+ KK K E E G++ EK PK+K
Sbjct: 123 EEIDAPKPKKMK----------KEKEMNGETREKSPKLK 151
Score = 36.2 bits (82), Expect = 0.070
Identities = 40/177 (22%), Positives = 63/177 (35%), Gaps = 13/177 (7%)
Query: 272 DEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQAR----KTASVLSKDDVAPESGD 327
+E K+ K E + E F K K+ KKK + + S +K P D
Sbjct: 28 EEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAKKKEEPSQND 87
Query: 328 TTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEI----PQLVPIGKKTPANEKVEI 383
+ K +K++ P K + K K SE+EI P+ + K+ + +
Sbjct: 88 ISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMNGETREKS 147
Query: 384 QKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVK 440
K G P NPS ++ + E P + P I EE +K
Sbjct: 148 PKLKNGFPHPEPDCNPSEAASEESNSEIEQEIPVEQKEGAFSNFP-----ISEETIK 199
Score = 32.0 bits (71), Expect = 1.3
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 8/135 (5%)
Query: 351 GKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKAL 410
GK + A ES+ + + + K+T EK E K + + A+ P+ K+ K
Sbjct: 3 GKLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPK-SDKTEEIAEEEETVFPKAKQVKK- 60
Query: 411 PASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSV 470
KA SE SP+ K K+E + S K R+ + E K ++ +K V
Sbjct: 61 ------KAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKV 114
Query: 471 RKASHTPKKWPKKPK 485
K ++ PK
Sbjct: 115 TKNEEPSEEEIDAPK 129
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/225 (24%), Positives = 85/225 (37%), Gaps = 17/225 (7%)
Query: 277 RSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESK 336
RS K K++++ K+R+R+ K +R +A S D + + K +
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
Query: 337 K--EQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPA 394
++P +RG G A + + P K P++ + K K+ A
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK--KEKSA 347
Query: 395 KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQT 454
P+PS R PA TP AE P + +E V S + +D R
Sbjct: 348 TRPSPSPERSSTGPEPPAP-TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD-RSP 405
Query: 455 PKKPEAKFFTT----------PSKSVRKASHTPKKWPKKPKVPQS 489
PK PE ++ P+K R AS +P+ PK P S
Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES-PKPAPAPGS 449
Score = 42.7 bits (99), Expect = 7e-04
Identities = 56/215 (26%), Positives = 94/215 (43%), Gaps = 19/215 (8%)
Query: 282 KKKKEARRKRRERNFEKQ--KERKKKRQQARKTASVLSKDDVAPESGDTTVKKPE-SKKE 338
K++ E R E E+Q +E++ + + A +L KD +T ++P ++
Sbjct: 63 KRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETH 122
Query: 339 QTPEHGKKKRGRGKAQVKATNESEDEI---PQLVPIGKKTPANEKVEIQKHATGKKSPAK 395
Q E +KK R +A ++ D PQ K PA E + + S ++
Sbjct: 123 QLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYS-LVRESSSSR 181
Query: 396 SPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTP 455
SP P + KK+K + + +ES +P + +K K K K +S S KK ++P
Sbjct: 182 SPTPKQKKKKKKK-----DRGRRSESSSPRRERKKSSKKK----KHRSESESKKRKHRSP 232
Query: 456 KKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
P++K + K R S TP PK + +ST
Sbjct: 233 -TPKSKRKSKDKKRKRSRSTTPA--PKSRRAHRST 264
Score = 42.7 bits (99), Expect = 7e-04
Identities = 61/261 (23%), Positives = 86/261 (32%), Gaps = 55/261 (21%)
Query: 276 KRSLLNKKKKEARRK-----RRERN------------------------FEKQKERKKKR 306
K+ KKK RR RRER K+K + KKR
Sbjct: 186 KQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR 245
Query: 307 QQARKTASV-------LSKDDVAPESGDTTVKKPESKKEQT---------PEHGKKKRGR 350
+++R T S + S DT+ + S +T P +RG
Sbjct: 246 KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
Query: 351 GKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKAL 410
G A + + P K P++ + K K+ A P+PS R
Sbjct: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYED--KDKDKKEKSATRPSPSPERSSTGPEP 363
Query: 411 PASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPE------AKFFT 464
PA TP AE P + +E V S + +D R PK PE + +
Sbjct: 364 PA-PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD-RSPPKSPEKLPQSSSSESS 421
Query: 465 TPSKSVRKASHTPKKWPKKPK 485
PS K S P+ PK
Sbjct: 422 PPSPQPTKVSRHASSSPESPK 442
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/235 (20%), Positives = 92/235 (39%), Gaps = 54/235 (22%)
Query: 280 LNKKKKEARRKR--------RERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVK 331
LN+KK E R +F+ Q+ ++ +Q A + P + V+
Sbjct: 127 LNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPE-----------PPKPYSLVR 175
Query: 332 KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKK 391
+ S + TP+ KKK+ + + + SE P+ ++ +++K + + + KK
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGR-----RSESSSPR----RERKKSSKKKKHRSESESKK 226
Query: 392 SPAKSPNP----------------STPRGKKRKALPASETPKAAESETP---GKSPEKKP 432
+SP P +TP K R+A ++ A+ S+T +S K
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
Query: 433 KIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVP 487
A + SP+ G++ P F+ P + + +P+ K+P P
Sbjct: 287 HTTALAGRSPSPASGRRGEGDAP-------FSEPGTTSTQRPSSPETATKQPSSP 334
Score = 39.7 bits (91), Expect = 0.006
Identities = 49/233 (21%), Positives = 84/233 (36%), Gaps = 30/233 (12%)
Query: 277 RSLLNKKKKEARRKRRERNFE------KQKERKKKRQQARKTASVLSKDDVAPESGDTTV 330
RSL + + K R R+ KQK + R+ ++ +K P ++
Sbjct: 760 RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS 819
Query: 331 KKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGK 390
P +K +TP +VK+ P+ I + V Q+ + +
Sbjct: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTP-----PRQGSITSPQANEQSVTPQRRSCFE 874
Query: 391 KSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEK----KPKIK-------EEAV 439
SP TP R + S P+ S P +SP + +PK+K
Sbjct: 875 SSPDPELKSRTP---SRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS 931
Query: 440 KEKSPSLGKKDARQTPKKPE--AKFFTTPSKSVRKASHTPKKWPK---KPKVP 487
SPS + +R TP++ + S+ + + SH+ P KP+ P
Sbjct: 932 GSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP 984
Score = 38.5 bits (88), Expect = 0.014
Identities = 42/218 (19%), Positives = 86/218 (39%), Gaps = 23/218 (10%)
Query: 277 RSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESK 336
RSL+ + + +R +R ERK K + +++ S+ + +PE + + S+
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRR----SRSNSSPEMKKSRISSRRSR 760
Query: 337 KEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKS 396
+P K R + + ++ + Q P ++ ++ Q A + P +S
Sbjct: 761 SLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS-----QPKAKSRTPPRRS 815
Query: 397 PNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPK 456
+ S+P K++ P+ ++ ++ SP PK+K + S+ A +
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSS-------SP--HPKVK-SGTPPRQGSITSPQANEQSV 865
Query: 457 KPEAKFFTTPSKSVRKASHTPKK----WPKKPKVPQST 490
P+ + S S TP + P+V ST
Sbjct: 866 TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST 903
Score = 37.7 bits (86), Expect = 0.024
Identities = 40/223 (17%), Positives = 86/223 (38%), Gaps = 21/223 (9%)
Query: 275 TKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDT-TVKKP 333
TKR + + RR R + + + + +++ + S+ G + + ++
Sbjct: 501 TKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG 560
Query: 334 ESKKEQTPEHGKKK------RGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHA 387
S G+ + RGR +++ A S P +TPA +
Sbjct: 561 RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 388 TGKKSPAKSP--------NPSTPRGKKRKALPASETPKAAESETP---GKSPEKKPKIKE 436
++S +SP +P+ G+ R PA + S TP G+S + P +
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR--GRSRSRTPARRGRSRSRTPARRS 678
Query: 437 EAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKK 479
+ ++P+ + +TP++ ++ + + R S TP++
Sbjct: 679 GRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRG-RSHSRTPQR 720
Score = 37.0 bits (84), Expect = 0.041
Identities = 35/201 (17%), Positives = 75/201 (37%), Gaps = 2/201 (0%)
Query: 283 KKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE 342
K + ARR R K K R R+++ +++ L++ + PE++ P
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 343 HGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTP 402
H + + + S P K T + K ++S ++S T
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783
Query: 403 RGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKF 462
++R +S++ + +S + + +SP+ ++ +R + ++ +
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA-RQESSRTSSRRRRGRS 1842
Query: 463 FTTPSKSVRKASHT-PKKWPK 482
T P+ R S T P W +
Sbjct: 1843 RTPPTSRKRSRSRTSPAPWKR 1863
Score = 36.2 bits (82), Expect = 0.070
Identities = 40/191 (20%), Positives = 72/191 (37%), Gaps = 15/191 (7%)
Query: 305 KRQQARKTASVLSKDDVAPESGDTTVKKPESK-KEQTPEHGKKKRGRGKAQVKATNESED 363
+R ++ + + K +P+ + P+SK K +TP ++R R + + ++S
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP---LRQRSRSGSSPEVDSKSRL 1591
Query: 364 EIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASET----PKAA 419
P+ G +K A + P PR R++ S + P
Sbjct: 1592 S-PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 420 ESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKK------PEAKFFTTPSKSVRKA 473
S + SPE PK + +S K +R P++ PE S+ R A
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Query: 474 SHTPKKWPKKP 484
S +P+ + P
Sbjct: 1711 SSSPETRSRTP 1721
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/157 (17%), Positives = 59/157 (37%), Gaps = 18/157 (11%)
Query: 338 EQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKS- 396
E TP +K+R + +++ S + ++ ++ SPAK
Sbjct: 2597 EPTPAK-RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Query: 397 ----PNPSTPR----GKKRKALPASETPKAAES--------ETPGKSPEKKPKIKEEAVK 440
P P++P+ G++R P +S E SP+ P+ ++ +
Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Query: 441 EKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTP 477
E+ G++ ++P + +P ++S +P
Sbjct: 2716 ERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 30.0 bits (66), Expect = 5.0
Identities = 26/154 (16%), Positives = 61/154 (39%), Gaps = 6/154 (3%)
Query: 335 SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPA 394
S+ + E K + + ++ + + + P+ +++ + E+ + + SP
Sbjct: 1537 SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS--RLSPR 1594
Query: 395 KSPNPSTPRGK-KRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQ 453
+S + S+P K K +A P +++ + E +P P+ K + +
Sbjct: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 454 TPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVP 487
T PE S++ R+ S + + K + P
Sbjct: 1655 TESSPE---HPPKSRTARRGSRSSPEPKTKSRTP 1685
Score = 30.0 bits (66), Expect = 5.0
Identities = 29/178 (16%), Positives = 62/178 (34%), Gaps = 20/178 (11%)
Query: 320 DVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANE 379
DV T ++P + P ++ + +++ S G + +E
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 380 --KVEIQKHATGKKSPAKSPNPS-----------TPRGKKRKALPASETPKAAESETPGK 426
+ +Q K+ P+ +P P TP +KR++ +S + ++ S +
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS--SSSSSSSSSSSSSSS 2622
Query: 427 SPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVR-----KASHTPKK 479
S + S S + +P KP + P+ + + S +P+K
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRK 2680
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/299 (21%), Positives = 113/299 (37%), Gaps = 47/299 (15%)
Query: 228 ENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEA 287
ENI + E K E +K ++ EK A++ D+ K S K+++
Sbjct: 114 ENIAGIPSAFLEL---KKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSR 170
Query: 288 RRKRRE--------RNFEKQKERKKK-------RQQARKTASVLSKDDVAPESGDTTVK- 331
+RR+ R+ ++ERK+ R ++R + K + PE + +VK
Sbjct: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKV 230
Query: 332 ------------------KPE---SKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP 370
KPE KE +PE KK K + K S
Sbjct: 231 KEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKE---KEKEKTRPRSRSRSKSRSR 287
Query: 371 IGKKTPANEKVEIQKHATGKK-SPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPE 429
++P++ + + + + SP + P+P +R+ P P + +SP
Sbjct: 288 TRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS--RSPV 345
Query: 430 KKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVR-KASHTPKKWPKKPKVP 487
++ + ++ S S +R PKKP + + P K+ R S +P + +P P
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404
Score = 42.7 bits (99), Expect = 7e-04
Identities = 45/204 (22%), Positives = 77/204 (37%), Gaps = 15/204 (7%)
Query: 275 TKR---SLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVK 331
TKR SL +K +K + R R + K+ R A S G ++
Sbjct: 649 TKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS-- 706
Query: 332 KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVP--------IGKKTPANEKVEI 383
P+ ++ +P +R + K ++ PQ V G PA +K
Sbjct: 707 SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766
Query: 384 QKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKS 443
+SP+ + +P+ P K + P+ P+ ++ E GK +KK K + K+K
Sbjct: 767 PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK--KDKK 824
Query: 444 PSLGKKDARQTPKKPEAKFFTTPS 467
KK ++ A TP+
Sbjct: 825 HKKHKKHKKEKAVAAAAAAAVTPA 848
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/226 (21%), Positives = 87/226 (38%), Gaps = 41/226 (18%)
Query: 281 NKKKKEARRKRRERNFEKQKERKK-----------KRQQARKTASVLSKDDVAPESGDTT 329
N KK++ + K R R+ + K R + +R+ ++ S + +P +
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP 323
Query: 330 VKK-PESKKEQTPEHGK-----KKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEI 383
++ P + P H + ++R R A + ++ S P KK P
Sbjct: 324 RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP-PKKPPKRTS--- 379
Query: 384 QKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKS 443
+ +K+ SP+ S PR + R + PA+ PK S TP +S + S
Sbjct: 380 ---SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRK-------SRVS 429
Query: 444 PSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQS 489
S G+ + T K K + S +P P+K ++ +S
Sbjct: 430 VSPGRTSGKVTKHKGTEK----------RESPSPAPKPRKVELSES 465
Score = 37.0 bits (84), Expect = 0.041
Identities = 40/210 (19%), Positives = 84/210 (40%), Gaps = 25/210 (11%)
Query: 300 KERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATN 359
K + +++++ A K +++ D K + Q +++ + + +++
Sbjct: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
Query: 360 ESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASET---- 415
SEDE P+ + K + + SP K ++PRG++R++ T
Sbjct: 501 SSEDERPKRSHV-KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR 559
Query: 416 -------PKAAESETPG---KSPEKKPKIKEEAVKEKSPSLGKKDARQTPKK-------P 458
P+ + TP ++P P+ + + + SP + ++ + P K P
Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
Query: 459 EAKFFTTPSKSV-RKASHTPKKWPKKPKVP 487
K +PS R+ SH+P PK+ P
Sbjct: 620 PPKRRASPSPPPKRRVSHSPP--PKQRSSP 647
Score = 35.4 bits (80), Expect = 0.12
Identities = 53/246 (21%), Positives = 94/246 (38%), Gaps = 41/246 (16%)
Query: 269 SNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDT 328
S+ DE KRS + K E R+RR +KRQ K S + +P T
Sbjct: 501 SSEDERPKRS--HVKNGEVGRRRRHSPSRSASPSPRKRQ---KETSPRGRRRRSPSPPPT 555
Query: 329 TVKK-----PESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLV-------------- 369
++ P ++ +TP ++R + + P +
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615
Query: 370 --PIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPR------GKKRKALPASETPKAAES 421
P K A+ ++ + P + +P T R K RK S + + A S
Sbjct: 616 SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675
Query: 422 ETPGK--SPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKK 479
P K SP +P+ + + SP ++ A +P++ ++ + ++ +R+ S TP+
Sbjct: 676 PQPNKRHSPSPRPRAPQTS---SSPPPVRRGASSSPQRRQSP--SPSTRPIRRVSRTPE- 729
Query: 480 WPKKPK 485
PKK K
Sbjct: 730 -PKKIK 734
Score = 33.1 bits (74), Expect = 0.59
Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 282 KKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPE----SGDTTVKKPESKK 337
KKKK+ ++ ++++ +K K+ KK++ A A+ ++ +A + + V PE KK
Sbjct: 811 KKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKK 870
Query: 338 EQTPE 342
E E
Sbjct: 871 ETESE 875
Score = 32.3 bits (72), Expect = 1.0
Identities = 44/204 (21%), Positives = 71/204 (34%), Gaps = 16/204 (7%)
Query: 282 KKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTP 341
K++ KRR + + +K +R T S S + P++ P
Sbjct: 642 KQRSSPVTKRRSPSLSSK--HRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP 699
Query: 342 EHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPST 401
+RG + + + S P PI + + E +I+K A+ SP S+
Sbjct: 700 V----RRGASSSPQRRQSPS----PSTRPIRRVSRTPEPKKIKKAAS--PSPQSVRRVSS 749
Query: 402 PRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAK 461
R PA++ P A S +SP K KSP+ R + ++ K
Sbjct: 750 SRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGK 809
Query: 462 FFTTPSKSVRKASHTPKKWPKKPK 485
K + H K KK K
Sbjct: 810 ----KKKKKKDKKHKKDKKHKKHK 829
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 50.1 bits (118), Expect = 5e-06
Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 33/242 (13%)
Query: 270 NWDEATKRSLLNKKKKEARRKR---RERNFEKQKERKKKRQQARKTASVLSKDDVAPESG 326
N + ++ RS K K E + ++R+ + KER + R +K+ + ++ E
Sbjct: 156 NGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGI---EIVKEK- 211
Query: 327 DTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGK-KTPANEKVEIQ- 384
T K E KK ++P KR + + Q + + IGK ++P ++KV+I+
Sbjct: 212 TTRSKSKERKKSKSPS----KRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIED 267
Query: 385 --KHATGKKSPA-----------KSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKK 431
K KKSP KS +P RGK + S+ K+ SET EKK
Sbjct: 268 KSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSET---DKEKK 324
Query: 432 PKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTP---KKWPKKPKVPQ 488
P IK + S + +R+ + P+ + + + + S +P + K+ K P
Sbjct: 325 P-IKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPS 383
Query: 489 ST 490
T
Sbjct: 384 RT 385
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/221 (22%), Positives = 93/221 (42%), Gaps = 36/221 (16%)
Query: 272 DEATKRSLLNKKKKEARR---KRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDT 328
D++ + +KKKK R K+ + + E+ K++K K + K D + + G +
Sbjct: 34 DQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMS 93
Query: 329 TVKKPESKKEQTPEHGKKKRGRGKAQV--------------------KATNESEDEIPQL 368
K+ + E +K+R KA++ ++ +E E EI +
Sbjct: 94 PAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEK 153
Query: 369 VPIGKKTPANE-----KVEI--QKHATGKKSPAKSPNPSTPRGKKRKALPASE------T 415
G ++ K+E+ K T K+S ++S + R K+K+ E T
Sbjct: 154 ARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTT 213
Query: 416 PKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPK 456
++ KSP K+ K +++A K KSP+L ++ + K
Sbjct: 214 RSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGK 254
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 23/222 (10%)
Query: 245 WESVKLLFVKTEK-SAALPIFSSFVS-NWDEATKRSLLNKKKKEARRKRRERNFEKQKER 302
WE VK K +K S AL F ++ NW K+ ++ R K + K+R
Sbjct: 31 WEEVKEQLEKKKKGSKALAEFEEKMNENW---------KKELEKHREKLLSGSESSSKKR 81
Query: 303 KKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESE 362
++K+++ +K+ S + +S ++ + K+Q KKK K+ + +E+E
Sbjct: 82 QRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETE 141
Query: 363 DEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASE------TP 416
+ + KK + + E +K G K + P ++L SE
Sbjct: 142 SDSKD--SLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSS--ESLSESEYIEEVRAK 197
Query: 417 KAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKP 458
K SE K+ EK K K+ K+ S KK A +P P
Sbjct: 198 KKKSSEEREKATEKTKKKKKH--KKHSKKKKKKAASSSPDSP 237
Score = 43.5 bits (101), Expect = 4e-04
Identities = 51/225 (22%), Positives = 90/225 (40%), Gaps = 27/225 (12%)
Query: 271 WDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTV 330
W+E ++ L KKKK ++ FE++ K++ + +LS + +
Sbjct: 31 WEEVKEQ--LEKKKKGSKALAE---FEEKMNENWKKELEKHREKLLSGSESS-------- 77
Query: 331 KKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKT-PANEKVEIQKHATG 389
SKK Q + KKK GR + ++++S KK +K + + H +
Sbjct: 78 ----SKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSS 133
Query: 390 KKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK- 448
+ S +++ + S KK+K ++ E E K KK K+ E S SL +
Sbjct: 134 ESSMSETESDSKDSLKKKK-----KSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSES 188
Query: 449 ---KDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
++ R KK + K+ +K H KK K S+
Sbjct: 189 EYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSS 233
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 23/222 (10%)
Query: 245 WESVKLLFVKTEK-SAALPIFSSFVS-NWDEATKRSLLNKKKKEARRKRRERNFEKQKER 302
WE VK K +K S AL F ++ NW K+ ++ R K + K+R
Sbjct: 41 WEEVKEQLEKKKKGSKALAEFEEKMNENW---------KKELEKHREKLLSGSESSSKKR 91
Query: 303 KKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESE 362
++K+++ +K+ S + +S ++ + K+Q KKK K+ + +E+E
Sbjct: 92 QRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETE 151
Query: 363 DEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASE------TP 416
+ + KK + + E +K G K + P ++L SE
Sbjct: 152 SDSKD--SLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSS--ESLSESEYIEEVRAK 207
Query: 417 KAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKP 458
K SE K+ EK K K+ K+ S KK A +P P
Sbjct: 208 KKKSSEEREKATEKTKKKKKH--KKHSKKKKKKAASSSPDSP 247
Score = 43.5 bits (101), Expect = 4e-04
Identities = 51/225 (22%), Positives = 90/225 (40%), Gaps = 27/225 (12%)
Query: 271 WDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTV 330
W+E ++ L KKKK ++ FE++ K++ + +LS + +
Sbjct: 41 WEEVKEQ--LEKKKKGSKALAE---FEEKMNENWKKELEKHREKLLSGSESS-------- 87
Query: 331 KKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKT-PANEKVEIQKHATG 389
SKK Q + KKK GR + ++++S KK +K + + H +
Sbjct: 88 ----SKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSS 143
Query: 390 KKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGK- 448
+ S +++ + S KK+K ++ E E K KK K+ E S SL +
Sbjct: 144 ESSMSETESDSKDSLKKKK-----KSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSES 198
Query: 449 ---KDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST 490
++ R KK + K+ +K H KK K S+
Sbjct: 199 EYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSS 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,616,997
Number of Sequences: 37866
Number of extensions: 997559
Number of successful extensions: 14421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 268
Number of HSP's successfully gapped in prelim test: 944
Number of HSP's that attempted gapping in prelim test: 7656
Number of HSP's gapped (non-prelim): 4474
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.