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Search of human proteins with 118498345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
(3703 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 7509 0.0
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 3643 0.0
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 532 e-150
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 531 e-150
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 531 e-150
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 86 5e-16
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 82 8e-15
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 80 5e-14
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 71 2e-11
gi|226246533 TOX high mobility group box family member 3 isoform... 70 3e-11
gi|226054295 TOX high mobility group box family member 3 isoform... 70 3e-11
gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 70 3e-11
gi|150170670 piccolo isoform 2 [Homo sapiens] 70 4e-11
gi|150378539 piccolo isoform 1 [Homo sapiens] 70 4e-11
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 70 4e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 69 1e-10
gi|169881277 PROP paired-like homeobox 1 [Homo sapiens] 67 3e-10
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 67 3e-10
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 67 3e-10
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 67 3e-10
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 67 3e-10
gi|226371655 zinc finger family member 674 isoform 2 [Homo sapiens] 67 4e-10
gi|89994742 zinc finger family member 674 isoform 1 [Homo sapiens] 67 4e-10
gi|33286444 mastermind-like 2 [Homo sapiens] 66 6e-10
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 66 6e-10
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 66 7e-10
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 66 7e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 66 7e-10
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 65 1e-09
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 65 1e-09
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 7509 bits (19482), Expect = 0.0
Identities = 3703/3703 (100%), Positives = 3703/3703 (100%)
Query: 1 MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNER 60
MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNER
Sbjct: 1 MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNER 60
Query: 61 LAESTASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPSARPPPPLREESASDTGEEG 120
LAESTASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPSARPPPPLREESASDTGEEG
Sbjct: 61 LAESTASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPSARPPPPLREESASDTGEEG 120
Query: 121 DEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSLPGAGGK 180
DEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSLPGAGGK
Sbjct: 121 DEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSLPGAGGK 180
Query: 181 QGDPSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKS 240
QGDPSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKS
Sbjct: 181 QGDPSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKS 240
Query: 241 NKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTH 300
NKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTH
Sbjct: 241 NKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTH 300
Query: 301 AVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGP 360
AVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGP
Sbjct: 301 AVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGP 360
Query: 361 GHSFYGKFSGIRMEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPL 420
GHSFYGKFSGIRMEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPL
Sbjct: 361 GHSFYGKFSGIRMEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPL 420
Query: 421 GPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEE 480
GPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEE
Sbjct: 421 GPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEE 480
Query: 481 EEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVL 540
EEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVL
Sbjct: 481 EEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVL 540
Query: 541 QTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESANKDNA 600
QTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESANKDNA
Sbjct: 541 QTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESANKDNA 600
Query: 601 TAPEPNESTEGDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSRSLGGHMT 660
TAPEPNESTEGDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSRSLGGHMT
Sbjct: 601 TAPEPNESTEGDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSRSLGGHMT 660
Query: 661 MMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARGESYT 720
MMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARGESYT
Sbjct: 661 MMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARGESYT 720
Query: 721 CGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAA 780
CGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAA
Sbjct: 721 CGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAA 780
Query: 781 AAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMT 840
AAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMT
Sbjct: 781 AAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMT 840
Query: 841 QIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMDSAASDAQFMMSGFQLDPAGPMA 900
QIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMDSAASDAQFMMSGFQLDPAGPMA
Sbjct: 841 QIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMDSAASDAQFMMSGFQLDPAGPMA 900
Query: 901 AMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDM 960
AMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDM
Sbjct: 901 AMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDM 960
Query: 961 LGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKE 1020
LGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKE
Sbjct: 961 LGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKE 1020
Query: 1021 GGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESG 1080
GGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESG
Sbjct: 1021 GGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESG 1080
Query: 1081 VEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFT 1140
VEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFT
Sbjct: 1081 VEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFT 1140
Query: 1141 IRRCPSTDPEEAIEDVEGPSETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISFPG 1200
IRRCPSTDPEEAIEDVEGPSETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISFPG
Sbjct: 1141 IRRCPSTDPEEAIEDVEGPSETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISFPG 1200
Query: 1201 SSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDM 1260
SSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDM
Sbjct: 1201 SSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDM 1260
Query: 1261 LNNKIHLQLHLTHLHSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGK 1320
LNNKIHLQLHLTHLHSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGK
Sbjct: 1261 LNNKIHLQLHLTHLHSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGK 1320
Query: 1321 QPETSEDLGKNILPSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTH 1380
QPETSEDLGKNILPSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTH
Sbjct: 1321 QPETSEDLGKNILPSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTH 1380
Query: 1381 FNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRT 1440
FNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRT
Sbjct: 1381 FNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRT 1440
Query: 1441 FQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLE 1500
FQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLE
Sbjct: 1441 FQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLE 1500
Query: 1501 DKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNIL 1560
DKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNIL
Sbjct: 1501 DKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNIL 1560
Query: 1561 LVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRSVLH 1620
LVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRSVLH
Sbjct: 1561 LVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRSVLH 1620
Query: 1621 QTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLL 1680
QTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLL
Sbjct: 1621 QTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLL 1680
Query: 1681 SQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQ 1740
SQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQ
Sbjct: 1681 SQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQ 1740
Query: 1741 QAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPF 1800
QAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPF
Sbjct: 1741 QAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPF 1800
Query: 1801 YIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSI 1860
YIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSI
Sbjct: 1801 YIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSI 1860
Query: 1861 AQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKE 1920
AQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKE
Sbjct: 1861 AQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKE 1920
Query: 1921 LAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENL 1980
LAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENL
Sbjct: 1921 LAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENL 1980
Query: 1981 EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP 2040
EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP
Sbjct: 1981 EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP 2040
Query: 2041 PPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPL 2100
PPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPL
Sbjct: 2041 PPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPL 2100
Query: 2101 MMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVL 2160
MMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVL
Sbjct: 2101 MMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVL 2160
Query: 2161 RQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLE 2220
RQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLE
Sbjct: 2161 RQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLE 2220
Query: 2221 ELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLN 2280
ELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLN
Sbjct: 2221 ELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLN 2280
Query: 2281 LPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRI 2340
LPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRI
Sbjct: 2281 LPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRI 2340
Query: 2341 FDLIKHQKKLCYKDEDEEGQDDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANN 2400
FDLIKHQKKLCYKDEDEEGQDDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANN
Sbjct: 2341 FDLIKHQKKLCYKDEDEEGQDDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANN 2400
Query: 2401 TASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQP 2460
TASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQP
Sbjct: 2401 TASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQP 2460
Query: 2461 EQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQL 2520
EQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQL
Sbjct: 2461 EQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQL 2520
Query: 2521 ANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPS 2580
ANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPS
Sbjct: 2521 ANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPS 2580
Query: 2581 NPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQR 2640
NPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQR
Sbjct: 2581 NPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQR 2640
Query: 2641 DKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQ 2700
DKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQ
Sbjct: 2641 DKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQ 2700
Query: 2701 FRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQM 2760
FRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQM
Sbjct: 2701 FRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQM 2760
Query: 2761 KGDIFDGTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSS 2820
KGDIFDGTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSS
Sbjct: 2761 KGDIFDGTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSS 2820
Query: 2821 VNLNFDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAM 2880
VNLNFDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAM
Sbjct: 2821 VNLNFDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAM 2880
Query: 2881 MAMSEYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDS 2940
MAMSEYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDS
Sbjct: 2881 MAMSEYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDS 2940
Query: 2941 GDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAK 3000
GDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAK
Sbjct: 2941 GDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAK 3000
Query: 3001 EKKSKLSMAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQL 3060
EKKSKLSMAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQL
Sbjct: 3001 EKKSKLSMAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQL 3060
Query: 3061 DKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQG 3120
DKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQG
Sbjct: 3061 DKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQG 3120
Query: 3121 IPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSS 3180
IPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSS
Sbjct: 3121 IPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSS 3180
Query: 3181 PTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKV 3240
PTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKV
Sbjct: 3181 PTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKV 3240
Query: 3241 KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPT 3300
KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPT
Sbjct: 3241 KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPT 3300
Query: 3301 ALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSL 3360
ALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSL
Sbjct: 3301 ALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSL 3360
Query: 3361 LQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPK 3420
LQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPK
Sbjct: 3361 LQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPK 3420
Query: 3421 PEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAA 3480
PEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAA
Sbjct: 3421 PEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAA 3480
Query: 3481 RSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCG 3540
RSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCG
Sbjct: 3481 RSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCG 3540
Query: 3541 EEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPP 3600
EEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPP
Sbjct: 3541 EEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPP 3600
Query: 3601 SAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDY 3660
SAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDY
Sbjct: 3601 SAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDY 3660
Query: 3661 SEESDTDLSQKSDGPASPVEGPKDPSCPKDSGLTSVGTDTFRL 3703
SEESDTDLSQKSDGPASPVEGPKDPSCPKDSGLTSVGTDTFRL
Sbjct: 3661 SEESDTDLSQKSDGPASPVEGPKDPSCPKDSGLTSVGTDTFRL 3703
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 3643 bits (9446), Expect = 0.0
Identities = 2019/3826 (52%), Positives = 2508/3826 (65%), Gaps = 382/3826 (9%)
Query: 1 MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNER 60
ME CDSP +S ++NG + T+L++ +P+K + ME E+ D+L+ +ER
Sbjct: 1 METCDSPPISRQENGQSTSKLCGTTQLDN-EVPEKVAGMEPDR-ENSSTDDNLKT--DER 56
Query: 61 LAE-----STASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPSARPPPPLREESASD 115
+E S +A ++KE+ CNEC+ SF SLQ YMEHHCP+AR P L++++ S+
Sbjct: 57 KSEALLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPV-LKDDNESE 115
Query: 116 TGEEGDEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPS-LFLNSL 174
E E+SDVENL GEIVYQPDGSAYI+E + G +G+ S + +FL+SL
Sbjct: 116 ISEL--EDSDVENLTGEIVYQPDGSAYIIEDSKE---SGQNAQTGANSKLFSTAMFLDSL 170
Query: 175 PGAGGKQGDPSCAAPV--YPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFR 232
AG K D S +AP+ YPQIINTFHIASS GK F DQAFPNTSALAG+ PVLHSFR
Sbjct: 171 ASAGEKS-DQSASAPMSFYPQIINTFHIASSLGKPFTA-DQAFPNTSALAGVGPVLHSFR 228
Query: 233 VFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFG 292
V+D+RHK KDYL SDGSAK+SCVSKDVPNNVDLSKFDG V GKRKP+LMCFLCKLSFG
Sbjct: 229 VYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFG 288
Query: 293 YVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLV 352
Y+RSFVTHAVHDHRMTL+++E+K+LSNK +SAIIQGIGKDKEPL+SFLEPK +P
Sbjct: 289 YIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHF 348
Query: 353 STANLIGPGHSFYGKFSGIRMEGEEALPAGSA---------AGPEQPQAGLLTPSTLLNL 403
ST NLIGP +F G +S +E ++LPAG A + EQP P +NL
Sbjct: 349 STTNLIGPDPTFRGLWSAFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNL 408
Query: 404 GGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEA 463
GGL+S V+ TPITSV L +S +K SE KD + +C K E+
Sbjct: 409 GGLSSLVVNTPITSVSLSHSSSESSKMSESKDQ-----------ENNCERPK------ES 451
Query: 464 EEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDL 523
E + E E +E+EED + +ELD+E E G S KD
Sbjct: 452 NVLHPNGECPVKSEPTEPGDEDEEDA-----YSNELDDE------EVLGELTDSIGNKDF 500
Query: 524 ALSNQSISNSPLMPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEG-VRANVA 582
L NQSIS PL +VL+ + +GT+S+S+ + D ++ + + G V +N
Sbjct: 501 PLLNQSIS--PLSSSVLKFIEKGTSSSSATVSD-----DTEKKKQTAAVRASGSVASNYG 553
Query: 583 EGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAGSLCELGV----GECPSGS 638
G+ DFAD SA+KD+ATA P+E GD+ HQH + G G+ GS
Sbjct: 554 ISGK--DFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPSTPGTPGPGGDGSPGS 611
Query: 639 GVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPG 698
G+ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPG
Sbjct: 612 GIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPG 671
Query: 699 GSCVYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQ 758
GSCVYCK+GQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNN+QNLQ
Sbjct: 672 GSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQ 731
Query: 759 NGGGEQVFSHTAGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARN 818
NG GEQVF H+A A ++ S CG PSP+KPK KPTWRCEVCDYETNVARN
Sbjct: 732 NGNGEQVFGHSAPAPNTSL----------SGCGTPSPSKPKQKPTWRCEVCDYETNVARN 781
Query: 819 LRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMD 878
LRIHMTSEKHMHNMMLLQQNM QIQHN HLGL +PAEAELYQYYLAQN+ L +K++
Sbjct: 782 LRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGL----APAEAELYQYYLAQNIGLTGMKLE 837
Query: 879 SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938
+ A D Q M++ FQLDPA AA+ P L GE +
Sbjct: 838 NPA-DPQLMINPFQLDPA-TAAALAPGL------------------------GELSPYIS 871
Query: 939 DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998
DP+LKLFQCAVCNKFT+D+L+ L +H++ ERSL E+EW+AV+GD YQCKLC YNTQLKAN
Sbjct: 872 DPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNYNTQLKAN 931
Query: 999 FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLH 1058
FQLHCKTDKH+QKYQLVAHIKEGGK+NEWRLKC+AIGNPVHLKCNACDYYTNS++KLRLH
Sbjct: 932 FQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIGNPVHLKCNACDYYTNSVDKLRLH 991
Query: 1059 TVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESL 1118
T N RHEA+LKLYKHLQ+ E V ESCYY+C +C+Y+TK KLNL+QHVRS+KHQ++E L
Sbjct: 992 TTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNLVQHVRSVKHQQTEGL 1051
Query: 1119 RKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEA----------IEDVEGPSETAADPEE 1168
RKLQ Q+GL E+++L +IF ++ CP + E A + + +E A P
Sbjct: 1052 RKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDLTEQHEEAEGAIKPTA 1111
Query: 1169 LAKDQEGGASSSQAEKELTDSPATSK-RISFPGSS-------ESPLSSKRPKTAEEIK-- 1218
+A+D E S E++ ++ ++K +S G + E +++KR K E+ K
Sbjct: 1112 VAEDDEKDTS----ERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATKRSKPTEDNKFC 1167
Query: 1219 PEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVA 1278
EQ YQCPYC Y++ D +R+++H ++QHSVQP++ CPLCQD+L+NK+HLQLHLTHLHSV+
Sbjct: 1168 HEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVS 1227
Query: 1279 PDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSN-----LEEAGKQPETSEDLGKNIL 1333
PDCVEKL+MTV P+++MP+SM LPAA ++ E +GK S K++
Sbjct: 1228 PDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGESPMDDKSMA 1287
Query: 1334 PSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTHFNEVHAKRPQLPV 1393
++ + ++K P +E W K ++ K LQ NE ++P L V
Sbjct: 1288 GLEDSKANVEVKNEEQKP--TKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKRQP-LSV 1344
Query: 1394 SDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHL 1453
SDRHVYKYRCN CSLAFKT++KLQ+HSQYH IRAATMC LCQRSFRTFQALKKHLE H
Sbjct: 1345 SDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHP 1404
Query: 1454 ELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLEDKQSPTGSDSGSV 1513
ELSEA++QQLY L NG+L A + +DH + E ++E E D E K SP GSDS S+
Sbjct: 1405 ELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSI 1464
Query: 1514 QEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKL 1573
+D GSEPKR LPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKL
Sbjct: 1465 PDDMGSEPKRTLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKL 1524
Query: 1574 KRALQESATGQPEPTSS-PDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAA 1632
K+ LQE+++ P+ T+S DNKP+KC+ CNVAYSQSSTLEIHMRSVLHQTKARAAKLE +
Sbjct: 1525 KKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPS 1584
Query: 1633 SGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPP 1692
+ G +++++ +P +L + +V
Sbjct: 1585 GHVAGGHSIAANVN---------------------------SPGQGMLDSMSLAAVNSKD 1617
Query: 1693 LGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQV 1752
+ + KE N+K+ D+I++ Q A Q+ AQ+
Sbjct: 1618 ----------THLDAKELNKKQTPDLISA------------------QPAHHPPQSPAQI 1649
Query: 1753 QAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPE 1812
Q LQ ELQQQAA Q Q NP LPHFPMT E LLQ QQ Q LFPFYIP EF L P+
Sbjct: 1650 QMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQ-FLFPFYIPGTEFSLGPD 1708
Query: 1813 VSLP--VTSGALTLTGTGPGLLEDLKAQVQVPQ---QSHQQILPQQQQN------QLSIA 1861
+ LP T G +TG LLEDLK Q+Q Q+ QIL QQ Q QL
Sbjct: 1709 LGLPGSATFGMPGMTGMAGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQ 1768
Query: 1862 QSHSALLQPSQHPEKKNKLVIKEKE-----------KESQRERDSAEGGEGNTGPK-ETL 1909
+ P Q +++ ++K+++ K+ +++ + E PK E +
Sbjct: 1769 KQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPEKPKQEFI 1828
Query: 1910 PDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQK 1969
+ KE K+ EPS+ PPRIAS ARGNA KALLENFGFELVIQYNEN+QKVQK
Sbjct: 1829 SEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQK 1888
Query: 1970 KNGKTDQGENLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKL 2029
K GK+ +GEN +KLEC +CGKLFSN+LILKSHQEHVH +FP+ LE+FA+QYR+ YDKL
Sbjct: 1889 K-GKSGEGENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKFARQYREAYDKL 1947
Query: 2030 YPLRPQTPEPPPPPPPPPPPPLPAAPPQPAS--------TPAIPASAPPITSPTIAPAQP 2081
YP+ P +PE PPPPPPPPP LP APPQP+S T + P APP T P P P
Sbjct: 1948 YPISPSSPETPPPPPPPPP--LPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005
Query: 2082 ------------SVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA 2129
+ P QL + ++LP+F +MMQ + LP QL QL ++ L ADL
Sbjct: 2006 PPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLT 2065
Query: 2130 QLYQHQL--NPTLLQQ-QNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQ 2186
QL Q QL +P L+ Q KRPRTRITDDQL++LR YFDINNSPSEEQI+EMA+KSGL Q
Sbjct: 2066 QLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQ 2125
Query: 2187 KVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPPKQEYWGSKRSSR 2246
KVIKHWFRNTLFKERQRNKDSPYNFSNPPIT LE+++ID +P S E K + SKRSSR
Sbjct: 2126 KVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFSKRSSR 2185
Query: 2247 TRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGE 2306
TRFTDYQLRVLQDFFD NAYPKDDE EQLS +LNLPTRVIVVWFQNARQKARK+YENQ E
Sbjct: 2186 TRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAE 2245
Query: 2307 GKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEDEEGQDDSQNE 2366
KD E+RELTN+RYIRTSN+ YQCKKC++VF RIFDLI HQKK CYKDED++ QD+SQ E
Sbjct: 2246 TKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTE 2305
Query: 2367 DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAG 2426
DSMDA + + + S A +A AP+A++ + ++ + + E + K E
Sbjct: 2306 DSMDATDQVVYKHCTVS-GQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364
Query: 2427 DEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQ 2486
EKP KQ P P Q +P + PQ S QP PQ
Sbjct: 2365 AEKP---------------KQSDPSPP-SQGTKPALPLASTSSDPPQ----ASTAQPQPQ 2404
Query: 2487 APPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQ 2546
PP+ P P + + +P PL S +LPPQL+ YQCDQC +AFP+ E WQ
Sbjct: 2405 PQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQ 2464
Query: 2547 EHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPST 2606
EHQ +HFL+AQNQF+H FL+R +DMP+M+FDP+NPL+ QLL ++ Q+P +++S +T
Sbjct: 2465 EHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTT 2524
Query: 2607 -PTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSN 2665
PT+ +LKRKL++K + E + G GE+ RDKRLRTTITPEQLEILY+KYLLDSN
Sbjct: 2525 APTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSN 2584
Query: 2666 PTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTA 2725
PTRKMLDHIA EVGLKKRVVQVWFQNTRARERKGQFRAVGPAQ+H+RCPFCRALFKAK+A
Sbjct: 2585 PTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSA 2644
Query: 2726 LEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFDGTSFSHLP------PSSSD 2779
LE+HIRSRHW+E K+AGY+L S ++ DGG + I+ + LP S ++
Sbjct: 2645 LESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIY--FDYPSLPLTKIDLSSENE 2702
Query: 2780 GQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDDCSSVN 2839
+PVSKT ELSP+ LLSPSS K E ED E+ + +DQ K D D+ SS+N
Sbjct: 2703 LASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSSIN 2762
Query: 2840 TAITDTTTGDEGNADNDSATGIATETKSSSAPNE-----GLTKAAMMAMSEY-EDRLSSG 2893
TAI+D TTGDEGN + +S TG + + K + +P E L K A +E +D+
Sbjct: 2763 TAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFLFS 2822
Query: 2894 LVSPAPSFYSKEYDN----------EGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDR 2943
L SP+ F K+ D+ + D SETSS+ADP SP+P S + KS S DR
Sbjct: 2823 LTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKS-KSNDR 2881
Query: 2944 PGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3003
PG KRFRTQM+NLQLKVLK+CF+DYRTPTM ECE+LGN+IGLPKRVVQVWFQNARAKEKK
Sbjct: 2882 PGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKK 2941
Query: 3004 SKLSMAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKE 3063
K+++ K F INQ EG K ECTLCG+KYSARLS+RDHIFS+QHISKV++T+GSQLD+E
Sbjct: 2942 FKINIGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDRE 3001
Query: 3064 KEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPP 3123
K+Y P TVRQLMAQQELDRIKKA++VLGL QQ GM D++ L ++LPTAYP L G+PP
Sbjct: 3002 KDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPP 3061
Query: 3124 VLLPGLNSP-SLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPT 3182
VLLPG+N P SLPGF ++ LT P ++G P++ SP L S P KP L +P
Sbjct: 3062 VLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKP---LLQTP- 3117
Query: 3183 PAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKE 3242
PPPPP PPP+ L QQ +Q+ + +K +
Sbjct: 3118 ---------------------------PPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTK 3150
Query: 3243 KEKAHKGKGEPLPVPKKE---KGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDP 3299
K K K E L K E K E ++A ++ + E VDP QLQALQ A+ DP
Sbjct: 3151 PNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKV-VGETHVDPIQLQALQNAIAGDP 3209
Query: 3300 TALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGS 3359
+ + QFLPYF+PGF+ Y+ PQ+PG +Q GY P+ GME LFPY P + Q L GLSPG+
Sbjct: 3210 ASFIGGQFLPYFIPGFASYFTPQLPGTVQGGYFPPVCGMESLFPYGPTMPQTLAGLSPGA 3269
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
LLQQYQQYQQ+LQE++Q+QQ++Q Q+QQQ+ VQ + K S + ++
Sbjct: 3270 LLQQYQQYQQNLQESLQKQQKQQ-QEQQQKPVQAKTSKVE---------SDQPQNSNDAS 3319
Query: 3420 KPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEA 3479
+ +E K+T E EEP+ ESKSAD D ++VP V+Y+ +CRKCQ F+DE+A
Sbjct: 3320 ETKEDKSTATE------STKEEPQLESKSAD-FSDTYVVPFVKYEFICRKCQMMFTDEDA 3372
Query: 3480 ARSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALC 3539
A +H KS C+FGQ +++ QE VL VP Y CLAC+ A+
Sbjct: 3373 AVNHQKSFCYFGQPLIDPQETVLRVPV--------------------SKYQCLACDVAIS 3412
Query: 3540 GEEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPP 3599
G EALSQHL+S+LHK +TI +A RNAKEH LLPHS C P+P+T STSQSAA SN++ P
Sbjct: 3413 GNEALSQHLQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPNPNTTSTSQSAASSNNTYPH 3472
Query: 3600 PSAAAPSSASPHASRKSWPQVVSRAS---AAKPPSFPP-LSSSSTVTSSSCSTSGVQPSM 3655
S S KSWP ++ +AS AA PPS PP LS STVTSS CSTSGVQ S+
Sbjct: 3473 LSC---------FSMKSWPNILFQASARRAASPPSSPPSLSLPSTVTSSLCSTSGVQTSL 3523
Query: 3656 PTDDYSEESDTDLSQKSDGPASPVEGPKDPSCPKDSGLTSVGTDTF 3701
PT+ S+ESD++LSQK + + +E P+ D S+ D F
Sbjct: 3524 PTESCSDESDSELSQKLEDLDNSLEVKAKPASGLDGNFNSIRMDMF 3569
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 532 bits (1370), Expect = e-150
Identities = 325/851 (38%), Positives = 455/851 (53%), Gaps = 103/851 (12%)
Query: 485 EEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSP---------L 535
+E DEGCK L S L+ +L RP + +SS ++ + + P L
Sbjct: 363 QEGDEGCKALI-SFLEPKLPARPSSD--IPLDNSSTVNMEANVAQTEDGPPEAEVQALIL 419
Query: 536 MPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESA 595
+ + LS + T++ S ++ + VA G D+ E
Sbjct: 420 LDEEVMALSPPSPPTATWDPSP----------------TQAKESPVAAGEAGPDWFPEGQ 463
Query: 596 NKDNATAPEPNESTE-GDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSR- 653
+D P N+S+ +GG +P +G E PS D +
Sbjct: 464 EEDGGLCPPLNQSSPTSKEGGTLP--------APVGSPEDPSDPPQPYRLADDYTPAPAA 515
Query: 654 ----SLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQP 709
SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE C YC +G
Sbjct: 516 FQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGA 575
Query: 710 HPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHT 769
HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q Q G G Q
Sbjct: 576 HPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQ----- 630
Query: 770 AGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHM 829
+ A++ S G +PKTK +W+C+VC YETN++RNLRIHMTSEKHM
Sbjct: 631 ---------GSPTEASLPPSAG---DKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHM 678
Query: 830 HNMMLLQQNMTQIQHNRHLGLGSLPSP-----AEAELYQYYLAQNMNLPNLKM------D 878
N+++L Q + +G G P P + EL+QY+ Q + P +
Sbjct: 679 QNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP 738
Query: 879 SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938
+AQ +++GF G A P G + D L QL+ +L S +
Sbjct: 739 DKPLEAQLLLNGFH--HVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 796
Query: 939 DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998
SLK+F+C VC F+TD+L++L H ++ RSL E EWK V GD+++CKLC Y TQLKAN
Sbjct: 797 SLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKAN 856
Query: 999 FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIG--------NPVHLKCNACDYYTN 1050
FQLH KTDKH QKYQL AH++EGG A ++G +P+HL+CN CD+ +N
Sbjct: 857 FQLHLKTDKHAQKYQLAAHLREGGGA-MGTPSPASLGDGAPYGSVSPLHLRCNICDFESN 915
Query: 1051 SLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSM 1110
S EK++LH + HE + ++YK E G+ YHC+LC + T ++L ++QH+R+
Sbjct: 916 SKEKMQLHARGAAHEENSQIYKVRLGAELGL------YHCLLCAWETPSRLAVLQHLRTP 969
Query: 1111 KHQRSESLRKLQRLQKGLPEEDEDLG---QIFTIRRCPSTDPEEAIEDVEGPSETAA-DP 1166
H+ +++ R+LQ LQ G P +E L I + P E + G S+ DP
Sbjct: 970 AHRDAQAQRRLQLLQNG-PTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDP 1028
Query: 1167 EELAKDQEGGA------SSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPE 1220
E ++ G + +KE + A SK + GS P + RP I
Sbjct: 1029 EGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGS--HPSLTLRPL---PICSL 1083
Query: 1221 QMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPD 1280
Q+Y CPYC + + + +++R H ++QH+VQP RCPLCQ+ L + L HL+HLH+V P+
Sbjct: 1084 QVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPE 1143
Query: 1281 CVEKLIMTVTT 1291
CVEKL++ V+T
Sbjct: 1144 CVEKLLLVVST 1154
Score = 256 bits (655), Expect = 2e-67
Identities = 214/705 (30%), Positives = 297/705 (42%), Gaps = 192/705 (27%)
Query: 2910 GTVDYSETSSLADPCSPSPGASGSAGKSGDSG--DRPGQKRFRTQMTNLQLKVLKSCFND 2967
G + S SSLA+P SP G + S G G +G D GQ+R+RTQM++LQLK++K+C+
Sbjct: 2246 GDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2304
Query: 2968 YRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKL---SMAKHFGINQTSYEGPKT 3024
YRTPTM ECEVLG +IGLPKRV+QVWFQNARAKEKK+KL + G ++ +T
Sbjct: 2305 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2364
Query: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRI 3084
+C C +KY +S R H+FS+QH++K+K+ + +QL E + +D L E
Sbjct: 2365 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYD------LAPAPEAPPA 2418
Query: 3085 KKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLL--PGLNSPSLPGFTPSNT 3142
KA A+ G A P L + PVLL P L P L P N+
Sbjct: 2419 LKAPPATTPASMPLG--------------AAPTLPRLAPVLLSGPALAQPPLGNLAPFNS 2464
Query: 3143 ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQ 3202
+ L+GL ++ +P+ + + P +P PQ+P Q
Sbjct: 2465 G-PAASSGLLGLATSVLPTTTVVQTAGPGRPL-----------------PQRPMPDQTNT 2506
Query: 3203 QQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKG 3262
P P P +P +KV + K P+ P
Sbjct: 2507 STAGTTDPVPGPPTEPL-----------------GDKVSSERK-------PVAGPTSSSN 2542
Query: 3263 EAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQ 3322
+A L+ L+A T+ P ALL QFLP+ +P P
Sbjct: 2543 DA-----------------------LKNLKALKTTVP-ALLGGQFLPFPLPPAGGTAPPA 2578
Query: 3323 IPG-ALQSGYLQPMYGM-EGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQ 3380
+ G LQ Y Q +YGM +GLFP +P + Q L+GL P +LLQ
Sbjct: 2579 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ------------------ 2620
Query: 3381 RQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPE 3440
PP P P + A PKP P+LP
Sbjct: 2621 -----------------------PP--PQPPEPTATAPPKP--------------PELPA 2641
Query: 3441 EPEAESKSADSLY---DPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNL 3497
E E+ D L V ++ +CR+C+ F E A +H +S CFFG+
Sbjct: 2642 PGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGS 2701
Query: 3498 QEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHR- 3556
L VP +YHCLACE L G EAL+ HL S+ H+ +
Sbjct: 2702 MPPPLRVPI--------------------CTYHCLACEVLLSGREALASHLRSSAHRRKA 2741
Query: 3557 ---------TITRAARNAK------EHPSLLPHSACFPDPSTAST 3586
+IT AA A + + LPH+ P +T ST
Sbjct: 2742 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2786
Score = 169 bits (427), Expect = 6e-41
Identities = 111/264 (42%), Positives = 150/264 (56%), Gaps = 40/264 (15%)
Query: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500
+QT E++ + +++E+ E++ +Q L +PP P+ PLP+ P
Sbjct: 1913 DQTLEEEEEEAERGEEEEEVEEEEVEEEQGL----------EPPAG---PEGPLPEP-PD 1958
Query: 2501 PSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQF 2560
+LS P++ A P + CDQC ++F S + H++LHFL +
Sbjct: 1959 GEELSQAEATKAGGKEPEEKATPSPSPA-HTCDQCAISFSSQDLLTSHRRLHFLPSLQPS 2017
Query: 2561 IHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEE 2620
PQ LD +P ++F NPL+A+ ++ P P LKRK E+
Sbjct: 2018 APPQLLD----LPLLVFGERNPLVAA-------------TSPMPGPP------LKRKHED 2054
Query: 2621 KASASPGENDSGTGGE-EPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVG 2679
S SP +++G GGE EP RDKRLRTTI PEQLEILY+ Y+ DSNPTRKMLD I+ EVG
Sbjct: 2055 -GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVG 2113
Query: 2680 LKKRVVQVWFQNTRARERKGQFRA 2703
LKKRVVQVWFQNTRARERKGQFR+
Sbjct: 2114 LKKRVVQVWFQNTRARERKGQFRS 2137
Score = 164 bits (414), Expect = 2e-39
Identities = 176/722 (24%), Positives = 273/722 (37%), Gaps = 207/722 (28%)
Query: 1489 VEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRA-----LPFRKGPNFTMEKFLDPSR 1543
V E + D+ + + G+ E +EP A L +RK NF ++KFLDP+R
Sbjct: 1348 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPAR 1407
Query: 1544 PYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNV 1603
P+KC C
Sbjct: 1408 ---------------------------------------------------PYKCTVCKE 1416
Query: 1604 AYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTF 1663
+++Q + L +H SV H K + A ++ ++ + G + + ++ P +
Sbjct: 1417 SFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCR---- 1472
Query: 1664 TTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQ 1723
+ N SS ++L Q + G + I P R
Sbjct: 1473 VSYNQSSTLEIHMRSVLHQTRSR-------GTKTDSKIEGPE----------------RS 1509
Query: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMT 1783
Q++ ++ + + + +++ + + + + LF P +LP FP+
Sbjct: 1510 QEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLV 1569
Query: 1784 TETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQ 1843
E+LL+LQQQQ LL PFY+ + ++ P+ LTL G P L L A P
Sbjct: 1570 PESLLKLQQQQ-LLLPFYLH--DLKVGPK---------LTLAGPAPVL--SLPAATPPPP 1615
Query: 1844 QSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNT 1903
PQ + +L+ E+E +R + EG E
Sbjct: 1616 -------PQPPKAELA--------------------------EREWERPPMAKEGNEAG- 1641
Query: 1904 GPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNEN 1963
PS P + ++A A KALLENFGFELVIQYNE
Sbjct: 1642 -------------------------PSSPPDPLPNEAARTAAKALLENFGFELVIQYNEG 1676
Query: 1964 KQKVQKKNGKTDQGENL---EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAK 2020
KQ V E L +KL C +CGKLFSN+LILK+H+EHVH+ + PF+ L R+A
Sbjct: 1677 KQAVPPPPTPPPP-EALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAA 1735
Query: 2021 QYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ 2080
Q+R YD LY P EPP PP P+P P P P P T AP +
Sbjct: 1736 QFRKSYDSLY---PPLAEPPKPPDGSLDSPVPHLGP-PFLVP------EPEAGGTRAPEE 1785
Query: 2081 PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTL 2140
S + E ++ LPP L
Sbjct: 1786 RSRAGGHWPIEEE--------------ESSRGNLPP-----------------------L 1808
Query: 2141 LQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKE 2200
+ + RT+ T+ Q + L+ +F+ + P + +++ +A GL +V+ WF+N K
Sbjct: 1809 VPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKA 1868
Query: 2201 RQ 2202
R+
Sbjct: 1869 RK 1870
Score = 114 bits (284), Expect = 2e-24
Identities = 129/504 (25%), Positives = 189/504 (37%), Gaps = 100/504 (19%)
Query: 2042 PPPPPPPPPLPAA------PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095
PPPPP PP A PP S+PP P A + L + + EL
Sbjct: 1612 PPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE-NFGFELV 1670
Query: 2096 IFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA-QLYQHQLNPTLLQQQNKRPRTRITD 2154
I Q +P P P LG + L +L+ + L +L+ + R
Sbjct: 1671 IQYNEGKQAVPPPPTPPP-PEALGGGDKLACGACGKLFSNML---ILKTHEEHVHRRFLP 1726
Query: 2155 DQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNP 2214
L +Y + +A+ P + DSP P
Sbjct: 1727 --FEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSL----------------DSPVPHLGP 1768
Query: 2215 PITSLEELKIDSRPPSPEPPKQEYW-----------------GSKRSSRTRFTDYQLRVL 2257
P E +R P +W +R SRT+FT++Q + L
Sbjct: 1769 PFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQAL 1828
Query: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTN 2317
Q FF+ +AYPKD E E+L++LL L +RV+VVWFQNARQKARKN G G +
Sbjct: 1829 QSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGAS 1888
Query: 2318 DRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD----EDEEGQDDSQNEDSMDAME 2373
C++C F +F+L++H KK CY D E+EE + + E+ ++ E
Sbjct: 1889 G-----------CRRCHATFSCVFELVRHLKK-CYDDQTLEEEEEEAERGEEEEEVEEEE 1936
Query: 2374 ILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLA 2433
+ P P P + EEL+ + T+AG ++P+
Sbjct: 1937 VEEEQGLE-----PPAGPEGPLPE------------PPDGEELSQAEA-TKAGGKEPEEK 1978
Query: 2434 EAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP 2493
PS P T ++ + + Q L L LP P APP
Sbjct: 1979 ATPSPSPAHTCDQCA--------------ISFSSQDLLTSHRRLHFLPSLQPSAPPQLLD 2024
Query: 2494 LP-----QSSPSPSQLSHLPLKPL 2512
LP + +P + S +P PL
Sbjct: 2025 LPLLVFGERNPLVAATSPMPGPPL 2048
Score = 76.6 bits (187), Expect = 4e-13
Identities = 138/601 (22%), Positives = 205/601 (34%), Gaps = 139/601 (23%)
Query: 2474 LVSLPSL-PQPPPQAP-----------PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLA 2521
++SLP+ P PPPQ P PP + S LP + T+ L
Sbjct: 1604 VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE 1663
Query: 2522 N---------------LPPQLIP-----------YQCDQCKLAFPSFEHWQEHQQLHFLS 2555
N +PP P C C F + + H++
Sbjct: 1664 NFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEE----H 1719
Query: 2556 AQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLK 2615
+F+ + L R +D P LA P+ P S SP P L
Sbjct: 1720 VHRRFLPFEALSRYAAQFRKSYDSLYPPLAEP------PKPPDGSLDSP-VPHLGPPFLV 1772
Query: 2616 RKLEEKASASPGENDSGTGGEEPQRDKRL----------------RTTITPEQLEILYQK 2659
+ E + +P E S GG P ++ RT T Q + L
Sbjct: 1773 PEPEAGGTRAPEER-SRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSF 1831
Query: 2660 YLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK-----GQFRAVGPAQAHRRCP 2714
+ + P ++ +A +GL RVV VWFQN R + RK G G C
Sbjct: 1832 FETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCR 1891
Query: 2715 FCRALFKAKTALEAHIR--------SRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFD 2766
C A F L H++ EA+R + ++ + GL+
Sbjct: 1892 RCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE------- 1944
Query: 2767 GTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFE--SPSMSSVNLN 2824
PP+ +G PL ELS + K G E E +PS S +
Sbjct: 1945 -------PPAGPEG---PLPEPPDGEELS-----QAEATKAGGKEPEEKATPSPSPAH-- 1987
Query: 2825 FDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMS 2884
D C +++ + D T + + S+ P L ++
Sbjct: 1988 ------TCDQC-AISFSSQDLLT-------SHRRLHFLPSLQPSAPPQ--LLDLPLLVFG 2031
Query: 2885 EYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRP 2944
E +++ P P K D S SP +GS G G+ P
Sbjct: 2032 ERNPLVAATSPMPGPPLKRKHEDG----------------SLSP--TGSEAGGGGEGEPP 2073
Query: 2945 GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKS 3004
KR RT + QL++L + PT + + ++GL KRVVQVWFQN RA+E+K
Sbjct: 2074 RDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKG 2133
Query: 3005 K 3005
+
Sbjct: 2134 Q 2134
Score = 71.2 bits (173), Expect = 2e-11
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 12/159 (7%)
Query: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPE 2651
A P+ A S ++ S+ ++L A + G GTG + +R RT ++
Sbjct: 2234 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSL 2293
Query: 2652 QLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGP----- 2706
QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2294 QLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGG 2353
Query: 2707 ------AQAHRRCPFCRALFKAKTALEAHIRSRHWHEAK 2739
A CP+C + + H+ SR H AK
Sbjct: 2354 SSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ-HLAK 2391
Score = 58.2 bits (139), Expect = 2e-07
Identities = 104/406 (25%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 2242 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK-N 2300
+R RT+ + QL++++ ++A P E E L + LP RVI VWFQNAR K +K
Sbjct: 2283 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2342
Query: 2301 YENQGEGKDGERRE--LTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKH---QKKLCYKDE 2355
+ G G E L R C C + + H ++ L E
Sbjct: 2343 LQGTAAGSTGGSSEGLLAAQR--------TDCPYCDVKYDFYVSCRGHLFSRQHLAKLKE 2394
Query: 2356 DEEGQDDSQNE--DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEA 2413
Q S+++ D A E + P + S P +A A + L+ A
Sbjct: 2395 AVRAQLKSESKCYDLAPAPE----APPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPA 2450
Query: 2414 ------EELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTP 2467
LA FNS A L A S P T + P L Q+ P+Q TNT
Sbjct: 2451 LAQPPLGNLAPFNSGPAA--SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ-TNTS 2507
Query: 2468 QQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLP-LKPLHTSTPQQLANLPPQ 2526
V P P P P + P+ S L LK L T+ P A L Q
Sbjct: 2508 TAGTTDPV--PGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVP---ALLGGQ 2562
Query: 2527 LIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLAS 2586
+P+ P + Q +F + M LF P NP++
Sbjct: 2563 FLPFPLPPAGGTAPPAVFGPQLQGAYF-------------QQLYGMKKGLF-PMNPMI-P 2607
Query: 2587 QLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSG 2632
Q L G +P P PT+T +L +PGE ++G
Sbjct: 2608 QTLIGLLPNALLQPPPQPPEPTATAPPKPPEL-----PAPGEGEAG 2648
Score = 53.5 bits (127), Expect = 4e-06
Identities = 52/210 (24%), Positives = 97/210 (46%), Gaps = 35/210 (16%)
Query: 2034 PQTPEPPPPPPPP--------------PPPPLPAAP-PQPASTP---AIPASAPPITSPT 2075
P PE P P PP P A P P PA T AI S+ + +
Sbjct: 1946 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 2005
Query: 2076 -----IAPAQPSVPLTQLSMPMELPIF---SPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127
+ QPS P L +P L +F +PL+ T P+ P + + G + P ++
Sbjct: 2006 RRLHFLPSLQPSAPPQLLDLP--LLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSE 2063
Query: 2128 LAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQK 2187
+ + ++KR RT I +QL +L +++ +++P+ + + ++++ GL ++
Sbjct: 2064 AGGGGEGE------PPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2117
Query: 2188 VIKHWFRNTLFKERQ-RNKDSPYNFSNPPI 2216
V++ WF+NT +ER+ + + +P +P +
Sbjct: 2118 VVQVWFQNTRARERKGQFRSTPGGVPSPAV 2147
Score = 50.4 bits (119), Expect = 3e-05
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 30/171 (17%)
Query: 2037 PEPPPPP-----PPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091
P+P PP P P PPLP PP P S P P + + A + + L+ S
Sbjct: 2195 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSAS 2254
Query: 2092 MELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTR 2151
SP T +P +G +R RT+
Sbjct: 2255 SLAEPESPGAGGTSGGPGGGTGVPDGMG-------------------------QRRYRTQ 2289
Query: 2152 ITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQ 2202
++ QL++++ ++ +P+ ++ + + ++ GLP++VI+ WF+N KE++
Sbjct: 2290 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2340
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 21/105 (20%)
Query: 724 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAA 783
+P++C VC S T K L +H S HL+ M+ AA +
Sbjct: 1407 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKK---------------------AAIDPS 1445
Query: 784 ANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKH 828
A GAP T T ++C VC N + L IHM S H
Sbjct: 1446 APARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLH 1490
Score = 48.1 bits (113), Expect = 2e-04
Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPT------SSPDNKP- 1595
+PY+C VC S T K L +H S HL L + Q GQ PT S+ D +P
Sbjct: 590 KPYRCDVCNYSTTTKGNLSIHMQSDKHLANL-QGFQAGPGGQGSPTEASLPPSAGDKEPK 648
Query: 1596 ----FKCNTCNVAYSQSSTLEIHMRSVLH 1620
++C C+ + S L IHM S H
Sbjct: 649 TKSSWQCKVCSYETNISRNLRIHMTSEKH 677
Score = 45.1 bits (105), Expect = 0.001
Identities = 81/389 (20%), Positives = 127/389 (32%), Gaps = 104/389 (26%)
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256
+++ ++++ + +Q PPA P P+ P D E++ + E G E P
Sbjct: 1929 EEEVEEEEVEEEQGLEPPAGPEGPLPEPP----------DGEELSQAEATKAGGKE--PE 1976
Query: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPY-----F 3311
K +P T + + + +L L + S P LL L +
Sbjct: 1977 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 2036
Query: 3312 VPGFSPYYAPQIPGALQSGYLQPM-----YGMEGLFPYSPALSQALMGLSPGSLLQQYQQ 3366
V SP P + + G L P G EG P L ++ P L Y+
Sbjct: 2037 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTIL---PEQLEILYRW 2093
Query: 3367 YQQ------SLQEAIQQQ--QQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP-------- 3410
Y Q + + I ++ ++++ Q Q + ++ K P G PSP
Sbjct: 2094 YMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATA 2153
Query: 3411 ---------------DKDPAKESPK----------------------PEEQKNTPREVSP 3433
D +E+PK P ++ TP P
Sbjct: 2154 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTP-EP 2212
Query: 3434 LLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQS 3493
LP LP P +E + P PK + AG + +A S
Sbjct: 2213 PLPLLPPPPPSEEEG------PEEPPKASPESEACSLSAGDLSDSSASS----------- 2255
Query: 3494 VVNLQEMVLHVPTGGGGGGSGGGGGGGGG 3522
L P G GG+ GG GGG G
Sbjct: 2256 --------LAEPESPGAGGTSGGPGGGTG 2276
Score = 43.5 bits (101), Expect = 0.004
Identities = 73/323 (22%), Positives = 117/323 (36%), Gaps = 57/323 (17%)
Query: 42 STGESHGPLDSLRAPFNERLAESTASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPS 101
+TG + P + + ++ + ST S +P + T +S Q +E C
Sbjct: 93 TTGTTPSPGHNAPSLPSDTFSSSTPSDSVTKDPPAASSTSENMRSSEPGGQL-LESGCGL 151
Query: 102 ARPP--------PPLREESASDTGEEGDEESDVE-------NLAGEIVYQPDGSAYIVES 146
P P +D G E D+E + E +L+ + + G AY+V
Sbjct: 152 VPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAK 211
Query: 147 LSQLTQGGGACGSGSGSGPLPSLFLNSLP-GAGGKQGDPSCAAPVYP--QIINTFHIASS 203
LS G LP F P G G + +PS YP + HI
Sbjct: 212 LSL---------PGGSELLLPKGF----PWGEAGIKEEPSLPFLAYPPPSHLTALHIQHG 258
Query: 204 FGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKSNKDYL---NSDGSAKSSCVSKDV 260
F P Q F ++ + S + RH + Y N G K +
Sbjct: 259 FD-----PIQGFSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSG 313
Query: 261 PNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNK 320
N+V + +C LC+L F ++F+ H H + L+ + + LS
Sbjct: 314 GNHVAV--------------FWLCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS 358
Query: 321 NISAIIQGIGKDKEPLVSFLEPK 343
A++Q + + L+SFLEPK
Sbjct: 359 --PAVLQEGDEGCKALISFLEPK 379
Score = 40.4 bits (93), Expect = 0.033
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 26/115 (22%)
Query: 3119 QGIPPVLLPGLNSPSLPGFTPSNTALTSPK-------PNLMGLPSTTVPSPGLPTSGLPN 3171
QG+P L PGL P P P TSP P +G P T + PGL P+
Sbjct: 686 QGLPLGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR----PD 739
Query: 3172 KPSSASL-------------SSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPP 3213
KP A L PT A +++ PP Q + PPP
Sbjct: 740 KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPP 794
Score = 40.4 bits (93), Expect = 0.033
Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 433 GKDSGAAEGEKQEVGDGDCFSEKVEPA----EEEAEEEEEEEEAEEEEEEEEEEEEEEED 488
G +G A G ++ C E V +++ EEEEEE EEEEE EEEE EE+
Sbjct: 1881 GGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEE 1940
Query: 489 EG 490
+G
Sbjct: 1941 QG 1942
Score = 40.0 bits (92), Expect = 0.043
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 451 CFSEK-VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
C+ ++ +E EEEAE EEEEE EEEE EEE+ E G +G P D E
Sbjct: 1910 CYDDQTLEEEEEEAERGEEEEEVEEEE--VEEEQGLEPPAGPEGPLPEPPDGE 1960
Score = 38.5 bits (88), Expect = 0.13
Identities = 37/167 (22%), Positives = 56/167 (33%), Gaps = 14/167 (8%)
Query: 3396 PKASQTPVPPGAPSPDKDPAKESPKP---EEQKNTPREVSPLLPKLPEE--PEAESKSAD 3450
P +P P P PD +P P EE++ T E+ P + P K+ +
Sbjct: 1337 PGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1396
Query: 3451 SLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510
D F+ P YK C C+ F+ + H S V +L +M
Sbjct: 1397 FALDKFLDPARPYK--CTVCKESFTQKNILLVHYNS-------VSHLHKMKKAAIDPSAP 1447
Query: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRT 3557
G + C C + L H+ S LH+ R+
Sbjct: 1448 ARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRS 1494
Score = 37.4 bits (85), Expect = 0.28
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 12/97 (12%)
Query: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRA--LQES--ATGQPEPTSSPDNKPF---- 1596
++C +C K +H + H K + A L+E A G P P S D P+
Sbjct: 842 HRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVS 901
Query: 1597 ----KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629
+CN C+ + +++H R H+ ++ K+
Sbjct: 902 PLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKV 938
Score = 37.0 bits (84), Expect = 0.36
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 2232 EPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQ 2291
EPP+ + RT QL +L ++ ++ P + +S + L RV+ VWFQ
Sbjct: 2071 EPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2124
Query: 2292 NARQKARK 2299
N R + RK
Sbjct: 2125 NTRARERK 2132
Score = 35.0 bits (79), Expect = 1.4
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 23/135 (17%)
Query: 3111 LPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLP 3170
LP A P+ PP + LNS S G TP SP N LPS T S P+ +
Sbjct: 73 LPGAAPST---PPSTMATLNSASTTGTTP------SPGHNAPSLPSDTF-SSSTPSDSVT 122
Query: 3171 NKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQP---PPTPQLPLQ 3227
P +AS +S M +P Q + V PP +P P P
Sbjct: 123 KDPPAASSTSEN-------MRSSEPGGQLLESGCGLV---PPKEIGEPQEGPDCGHFPPN 172
Query: 3228 QQQQRKDKDSEKVKE 3242
KDK+ E+ +E
Sbjct: 173 DPGVEKDKEQEEEEE 187
Score = 35.0 bits (79), Expect = 1.4
Identities = 123/613 (20%), Positives = 197/613 (32%), Gaps = 136/613 (22%)
Query: 1572 KLKRALQESATG-QPEPTSSPDNKP-FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629
+L +A A G +PE ++P P C+ C +++S L H R LH
Sbjct: 1961 ELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRR--LHFLP------ 2012
Query: 1630 EAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVG 1689
SL S P + F NP A +P + E
Sbjct: 2013 ----------------SLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGS 2056
Query: 1690 MPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQ 1749
+ P G+ G E + K+L I Q + + Q ++ +++
Sbjct: 2057 LSPTGSEAGGG----GEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2112
Query: 1750 AQVQAHLQQELQQQAALIQSQLFN------------------PTLLPHFPMTTE-----T 1786
+ +Q Q A + F P LP F + T
Sbjct: 2113 GLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGT 2172
Query: 1787 LLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGP-GLLEDLKAQVQVPQQS 1845
+ +++ FP+ P+A P+ LP A T T P LL + +
Sbjct: 2173 GREAPKREAPAFPY--PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEE 2230
Query: 1846 HQQILPQQQQNQLSIAQ----SHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEG 1901
+ P+ + LS S S+L +P E A G G
Sbjct: 2231 PPKASPESEACSLSAGDLSDSSASSLAEP---------------------ESPGAGGTSG 2269
Query: 1902 NTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIAS---DARGNATKALLENFGFEL-- 1956
G +PD + + + ++ S L +I +A T E G E+
Sbjct: 2270 GPGGGTGVPDGMGQRRYR-------TQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2322
Query: 1957 ---VIQY-------NENKQKVQKKNGKTDQGEN-----LEKLECDSCGKLFSNILILKSH 2001
VIQ E K K+Q + G + ++ +C C + + + H
Sbjct: 2323 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2382
Query: 2002 ---QEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP----PPPPPPPPPPLPAA 2054
++H+ +L+ + K Y L P PP PP P PL AA
Sbjct: 2383 LFSRQHL-------AKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAA 2435
Query: 2055 PPQPASTPAIPASAPPITSPTIAPAQP--SVPLTQLSMPMELPIFSPLMMQTMPLQTLPA 2112
P P P + S P + P + P S P + L + + ++ T +QT
Sbjct: 2436 PTLPRLAPVL-LSGPALAQPPLGNLAPFNSGPAASSGL---LGLATSVLPTTTVVQT--- 2488
Query: 2113 QLPPQLGPVEPLP 2125
GP PLP
Sbjct: 2489 -----AGPGRPLP 2496
Score = 35.0 bits (79), Expect = 1.4
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 2031 PLRPQT-----PEPPPPPPPPPPPPLPAAPPQPASTPA 2063
P+ PQT P PPP PP P APP+P PA
Sbjct: 2604 PMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPA 2641
Score = 34.7 bits (78), Expect = 1.8
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 9/103 (8%)
Query: 1483 EDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFL-DP 1541
E+ + EE+ EEE LE P G + + G E +A + G EK P
Sbjct: 1927 EEEEEVEEEEVEEEQGLE---PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSP 1983
Query: 1542 SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ 1584
S + C C SF+ +++L H LH L +LQ SA Q
Sbjct: 1984 SPAHTCDQCAISFSSQDLLTSH----RRLHFLP-SLQPSAPPQ 2021
Score = 33.9 bits (76), Expect = 3.1
Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 47/233 (20%)
Query: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDT-IGSQLD-KEKEYFDPATVRQLMAQQELD 3082
+CT+C + Y+ ++ H+ S H ++ + T S+++ E+ +P ++ + E+
Sbjct: 1467 KCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP---KEGETEGEVG 1523
Query: 3083 RIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPS--------- 3133
KK + G + F + P L+L +PA PPVL P P
Sbjct: 1524 TEKKGPDTSGFISGLP--FLSPPPPPLDLHR-FPAPLFTPPVLPPFPLVPESLLKLQQQQ 1580
Query: 3134 --LPGFTPS-----NTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQA 3186
LP + L P P ++ LP+ T P P P + + P A+
Sbjct: 1581 LLLPFYLHDLKVGPKLTLAGPAP-VLSLPAATPPPPPQPPKA---ELAEREWERPPMAKE 1636
Query: 3187 TMAMGPQQPPQQQQQQ-------------------QQPQVQQPPPPPAAQPPP 3220
GP PP + Q + +Q PPP PPP
Sbjct: 1637 GNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPP 1689
Score = 33.5 bits (75), Expect = 4.0
Identities = 42/141 (29%), Positives = 57/141 (40%), Gaps = 23/141 (16%)
Query: 375 GEEALPAGSAAGPEQPQAGL-------LTPSTLLNLGGLTSSVLK--TPITSVPLGPLAS 425
G LP + + P A L TPS N L S TP SV P A+
Sbjct: 69 GPARLPGAAPSTPPSTMATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDSVTKDPPAA 128
Query: 426 SPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEE---EEEE 482
S T SE S G+ E G G + P +E E +E + + E+++
Sbjct: 129 SST--SENMRSSEPGGQLLESGCG------LVPPKEIGEPQEGPDCGHFPPNDPGVEKDK 180
Query: 483 EEEEEDEGCKGLFPSELDEEL 503
E+EEE+E GL P +L L
Sbjct: 181 EQEEEEE---GLPPMDLSNHL 198
Score = 33.5 bits (75), Expect = 4.0
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 13/92 (14%)
Query: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFS 2098
PP P PPPP P +TP P P A QP PL + + P+ +
Sbjct: 693 PPGLMGPGPPPP-------PGATPTSPPELFQYFGPQ-ALGQPQTPLAGPGLRPDKPLEA 744
Query: 2099 PLMMQTM-----PLQTLPAQLPPQLGPVEPLP 2125
L++ P + P P L P LP
Sbjct: 745 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLP 776
Score = 33.1 bits (74), Expect = 5.3
Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 22/141 (15%)
Query: 2383 STP--MPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQP 2440
STP +PS A PA +A + F L + ++ G E PK EAP A P
Sbjct: 2137 STPGGVPSPAVKPPA-TATPASLPKFNLLLGKVDD--------GTGREAPK-REAP-AFP 2185
Query: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500
T P+P L P ++ TP + P LP LP PPP P++SP
Sbjct: 2186 YPTATLASGPQPFLP----PGKEATTPTPEPP----LPLLPPPPPSEEEGPEEPPKASPE 2237
Query: 2501 PSQLSHLPLKPLHTSTPQQLA 2521
S+ L L S+ LA
Sbjct: 2238 -SEACSLSAGDLSDSSASSLA 2257
Score = 32.7 bits (73), Expect = 6.9
Identities = 53/242 (21%), Positives = 79/242 (32%), Gaps = 38/242 (15%)
Query: 1247 SVQPM-LRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEK------------LIMTVTTPE 1293
SV P+ LRC +C N+K +QLH + K L+ TP
Sbjct: 899 SVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPS 958
Query: 1294 MVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLG--KNILPSASTE----------QS 1341
+ A D L+ P T E L ++IL + + ++
Sbjct: 959 RLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEA 1018
Query: 1342 GDLKPSPADPGSVREDSGFICW----------KKGCNQVFKTSAALQTHFNEVHAKRPQL 1391
G+ +P DP E+ C KK + S L + L
Sbjct: 1019 GNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPL 1078
Query: 1392 PVSDRHVYKYRCNQCSLAFKTIEKLQLHS-QYHVIRAATMCCLCQRSFRTFQALKKHLET 1450
P+ VY C CS +++ H+ H ++ C LCQ AL HL
Sbjct: 1079 PICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSH 1136
Query: 1451 SH 1452
H
Sbjct: 1137 LH 1138
Score = 32.7 bits (73), Expect = 6.9
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSP 2074
TPE P P P PP P +P+ +P P S P P
Sbjct: 1311 TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVP 1349
Score = 32.3 bits (72), Expect = 9.0
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Query: 2479 SLPQPPPQAPPPQC---PLPQSSPSPSQLSHLPLKPLHT-STPQQLANLPPQLIPYQCDQ 2534
+L QPPPQ P P P P P+P + + L T ST ++ + Y C Q
Sbjct: 2617 ALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHR---YLCRQ 2673
Query: 2535 CKLAFPSFEHWQEHQQ 2550
CK+AF HQ+
Sbjct: 2674 CKMAFDGEAPATAHQR 2689
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 531 bits (1369), Expect = e-150
Identities = 325/851 (38%), Positives = 455/851 (53%), Gaps = 103/851 (12%)
Query: 485 EEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSP---------L 535
+E DEGCK L S L+ +L RP + +SS ++ + + P L
Sbjct: 279 QEGDEGCKALI-SFLEPKLPARPSSD--IPLDNSSTVNMEANVAQTEDGPPEAEVQALIL 335
Query: 536 MPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESA 595
+ + LS + T++ S ++ + VA G D+ E
Sbjct: 336 LDEEVMALSPPSPPTATWDPSP----------------TQAKESPVAAGEAGPDWFPEGQ 379
Query: 596 NKDNATAPEPNESTE-GDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSR- 653
+D P N+S+ +GG +P +G E PS D +
Sbjct: 380 EEDGGLCPPLNQSSPTSKEGGTLP--------APVGSPEDPSDPPQPYRLADDYTPAPAA 431
Query: 654 ----SLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQP 709
SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE C YC +G
Sbjct: 432 FQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGA 491
Query: 710 HPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHT 769
HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q Q G G Q
Sbjct: 492 HPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQ----- 546
Query: 770 AGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHM 829
+ A++ S G +PKTK +W+C+VC YETN++RNLRIHMTSEKHM
Sbjct: 547 ---------GSPPEASLPPSAG---DKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHM 594
Query: 830 HNMMLLQQNMTQIQHNRHLGLGSLPSP-----AEAELYQYYLAQNMNLPNLKM------D 878
N+++L Q + +G G P P + EL+QY+ Q + P +
Sbjct: 595 QNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP 654
Query: 879 SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938
+AQ +++GF G A P G + D L QL+ +L S +
Sbjct: 655 DKPLEAQLLLNGFH--HVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 712
Query: 939 DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998
SLK+F+C VC F+TD+L++L H ++ RSL E EWK V GD+++CKLC Y TQLKAN
Sbjct: 713 SLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKAN 772
Query: 999 FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIG--------NPVHLKCNACDYYTN 1050
FQLH KTDKH QKYQL AH++EGG A ++G +P+HL+CN CD+ +N
Sbjct: 773 FQLHLKTDKHAQKYQLAAHLREGGGA-MGTPSPASLGDGAPYGSVSPLHLRCNICDFESN 831
Query: 1051 SLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSM 1110
S EK++LH + HE + ++YK E G+ YHC+LC + T ++L ++QH+R+
Sbjct: 832 SKEKMQLHARGAAHEENSQIYKVRLGAELGL------YHCLLCAWETPSRLAVLQHLRTP 885
Query: 1111 KHQRSESLRKLQRLQKGLPEEDEDLG---QIFTIRRCPSTDPEEAIEDVEGPSETAA-DP 1166
H+ +++ R+LQ LQ G P +E L I + P E + G S+ DP
Sbjct: 886 AHRDAQAQRRLQLLQNG-PTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDP 944
Query: 1167 EELAKDQEGGA------SSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPE 1220
E ++ G + +KE + A SK + GS P + RP I
Sbjct: 945 EGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGS--HPSLTLRPL---PICSL 999
Query: 1221 QMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPD 1280
Q+Y CPYC + + + +++R H ++QH+VQP RCPLCQ+ L + L HL+HLH+V P+
Sbjct: 1000 QVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPE 1059
Query: 1281 CVEKLIMTVTT 1291
CVEKL++ V+T
Sbjct: 1060 CVEKLLLVVST 1070
Score = 256 bits (655), Expect = 2e-67
Identities = 214/705 (30%), Positives = 297/705 (42%), Gaps = 192/705 (27%)
Query: 2910 GTVDYSETSSLADPCSPSPGASGSAGKSGDSG--DRPGQKRFRTQMTNLQLKVLKSCFND 2967
G + S SSLA+P SP G + S G G +G D GQ+R+RTQM++LQLK++K+C+
Sbjct: 2162 GDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220
Query: 2968 YRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKL---SMAKHFGINQTSYEGPKT 3024
YRTPTM ECEVLG +IGLPKRV+QVWFQNARAKEKK+KL + G ++ +T
Sbjct: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280
Query: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRI 3084
+C C +KY +S R H+FS+QH++K+K+ + +QL E + +D L E
Sbjct: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYD------LAPAPEAPPA 2334
Query: 3085 KKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLL--PGLNSPSLPGFTPSNT 3142
KA A+ G A P L + PVLL P L P L P N+
Sbjct: 2335 LKAPPATTPASMPLG--------------AAPTLPRLAPVLLSGPALAQPPLGNLAPFNS 2380
Query: 3143 ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQ 3202
+ L+GL ++ +P+ + + P +P PQ+P Q
Sbjct: 2381 G-PAASSGLLGLATSVLPTTTVVQTAGPGRPL-----------------PQRPMPDQTNT 2422
Query: 3203 QQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKG 3262
P P P +P +KV + K P+ P
Sbjct: 2423 STAGTTDPVPGPPTEPL-----------------GDKVSSERK-------PVAGPTSSSN 2458
Query: 3263 EAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQ 3322
+A L+ L+A T+ P ALL QFLP+ +P P
Sbjct: 2459 DA-----------------------LKNLKALKTTVP-ALLGGQFLPFPLPPAGGTAPPA 2494
Query: 3323 IPG-ALQSGYLQPMYGM-EGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQ 3380
+ G LQ Y Q +YGM +GLFP +P + Q L+GL P +LLQ
Sbjct: 2495 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ------------------ 2536
Query: 3381 RQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPE 3440
PP P P + A PKP P+LP
Sbjct: 2537 -----------------------PP--PQPPEPTATAPPKP--------------PELPA 2557
Query: 3441 EPEAESKSADSLY---DPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNL 3497
E E+ D L V ++ +CR+C+ F E A +H +S CFFG+
Sbjct: 2558 PGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGS 2617
Query: 3498 QEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHR- 3556
L VP +YHCLACE L G EAL+ HL S+ H+ +
Sbjct: 2618 MPPPLRVPI--------------------CTYHCLACEVLLSGREALASHLRSSAHRRKA 2657
Query: 3557 ---------TITRAARNAK------EHPSLLPHSACFPDPSTAST 3586
+IT AA A + + LPH+ P +T ST
Sbjct: 2658 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702
Score = 169 bits (427), Expect = 6e-41
Identities = 111/264 (42%), Positives = 150/264 (56%), Gaps = 40/264 (15%)
Query: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500
+QT E++ + +++E+ E++ +Q L +PP P+ PLP+ P
Sbjct: 1829 DQTLEEEEEEAERGEEEEEVEEEEVEEEQGL----------EPPAG---PEGPLPEP-PD 1874
Query: 2501 PSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQF 2560
+LS P++ A P + CDQC ++F S + H++LHFL +
Sbjct: 1875 GEELSQAEATKAGGKEPEEKATPSPSPA-HTCDQCAISFSSQDLLTSHRRLHFLPSLQPS 1933
Query: 2561 IHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEE 2620
PQ LD +P ++F NPL+A+ ++ P P LKRK E+
Sbjct: 1934 APPQLLD----LPLLVFGERNPLVAA-------------TSPMPGPP------LKRKHED 1970
Query: 2621 KASASPGENDSGTGGE-EPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVG 2679
S SP +++G GGE EP RDKRLRTTI PEQLEILY+ Y+ DSNPTRKMLD I+ EVG
Sbjct: 1971 -GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVG 2029
Query: 2680 LKKRVVQVWFQNTRARERKGQFRA 2703
LKKRVVQVWFQNTRARERKGQFR+
Sbjct: 2030 LKKRVVQVWFQNTRARERKGQFRS 2053
Score = 164 bits (414), Expect = 2e-39
Identities = 176/722 (24%), Positives = 273/722 (37%), Gaps = 207/722 (28%)
Query: 1489 VEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRA-----LPFRKGPNFTMEKFLDPSR 1543
V E + D+ + + G+ E +EP A L +RK NF ++KFLDP+R
Sbjct: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPAR 1323
Query: 1544 PYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNV 1603
P+KC C
Sbjct: 1324 ---------------------------------------------------PYKCTVCKE 1332
Query: 1604 AYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTF 1663
+++Q + L +H SV H K + A ++ ++ + G + + ++ P +
Sbjct: 1333 SFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCR---- 1388
Query: 1664 TTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQ 1723
+ N SS ++L Q + G + I P R
Sbjct: 1389 VSYNQSSTLEIHMRSVLHQTRSR-------GTKTDSKIEGPE----------------RS 1425
Query: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMT 1783
Q++ ++ + + + +++ + + + + LF P +LP FP+
Sbjct: 1426 QEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLV 1485
Query: 1784 TETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQ 1843
E+LL+LQQQQ LL PFY+ + ++ P+ LTL G P L L A P
Sbjct: 1486 PESLLKLQQQQ-LLLPFYLH--DLKVGPK---------LTLAGPAPVL--SLPAATPPPP 1531
Query: 1844 QSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNT 1903
PQ + +L+ E+E +R + EG E
Sbjct: 1532 -------PQPPKAELA--------------------------EREWERPPMAKEGNEAG- 1557
Query: 1904 GPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNEN 1963
PS P + ++A A KALLENFGFELVIQYNE
Sbjct: 1558 -------------------------PSSPPDPLPNEAARTAAKALLENFGFELVIQYNEG 1592
Query: 1964 KQKVQKKNGKTDQGENL---EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAK 2020
KQ V E L +KL C +CGKLFSN+LILK+H+EHVH+ + PF+ L R+A
Sbjct: 1593 KQAVPPPPTPPPP-EALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAA 1651
Query: 2021 QYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ 2080
Q+R YD LY P EPP PP P+P P P P P T AP +
Sbjct: 1652 QFRKSYDSLY---PPLAEPPKPPDGSLDSPVPHLGP-PFLVP------EPEAGGTRAPEE 1701
Query: 2081 PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTL 2140
S + E ++ LPP L
Sbjct: 1702 RSRAGGHWPIEEE--------------ESSRGNLPP-----------------------L 1724
Query: 2141 LQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKE 2200
+ + RT+ T+ Q + L+ +F+ + P + +++ +A GL +V+ WF+N K
Sbjct: 1725 VPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKA 1784
Query: 2201 RQ 2202
R+
Sbjct: 1785 RK 1786
Score = 114 bits (284), Expect = 2e-24
Identities = 129/504 (25%), Positives = 189/504 (37%), Gaps = 100/504 (19%)
Query: 2042 PPPPPPPPPLPAA------PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095
PPPPP PP A PP S+PP P A + L + + EL
Sbjct: 1528 PPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE-NFGFELV 1586
Query: 2096 IFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA-QLYQHQLNPTLLQQQNKRPRTRITD 2154
I Q +P P P LG + L +L+ + L +L+ + R
Sbjct: 1587 IQYNEGKQAVPPPPTPPP-PEALGGGDKLACGACGKLFSNML---ILKTHEEHVHRRFLP 1642
Query: 2155 DQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNP 2214
L +Y + +A+ P + DSP P
Sbjct: 1643 --FEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSL----------------DSPVPHLGP 1684
Query: 2215 PITSLEELKIDSRPPSPEPPKQEYW-----------------GSKRSSRTRFTDYQLRVL 2257
P E +R P +W +R SRT+FT++Q + L
Sbjct: 1685 PFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQAL 1744
Query: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTN 2317
Q FF+ +AYPKD E E+L++LL L +RV+VVWFQNARQKARKN G G +
Sbjct: 1745 QSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGAS 1804
Query: 2318 DRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD----EDEEGQDDSQNEDSMDAME 2373
C++C F +F+L++H KK CY D E+EE + + E+ ++ E
Sbjct: 1805 G-----------CRRCHATFSCVFELVRHLKK-CYDDQTLEEEEEEAERGEEEEEVEEEE 1852
Query: 2374 ILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLA 2433
+ P P P + EEL+ + T+AG ++P+
Sbjct: 1853 VEEEQGLE-----PPAGPEGPLPE------------PPDGEELSQAEA-TKAGGKEPEEK 1894
Query: 2434 EAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP 2493
PS P T ++ + + Q L L LP P APP
Sbjct: 1895 ATPSPSPAHTCDQCA--------------ISFSSQDLLTSHRRLHFLPSLQPSAPPQLLD 1940
Query: 2494 LP-----QSSPSPSQLSHLPLKPL 2512
LP + +P + S +P PL
Sbjct: 1941 LPLLVFGERNPLVAATSPMPGPPL 1964
Score = 76.6 bits (187), Expect = 4e-13
Identities = 138/601 (22%), Positives = 205/601 (34%), Gaps = 139/601 (23%)
Query: 2474 LVSLPSL-PQPPPQAP-----------PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLA 2521
++SLP+ P PPPQ P PP + S LP + T+ L
Sbjct: 1520 VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE 1579
Query: 2522 N---------------LPPQLIP-----------YQCDQCKLAFPSFEHWQEHQQLHFLS 2555
N +PP P C C F + + H++
Sbjct: 1580 NFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEE----H 1635
Query: 2556 AQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLK 2615
+F+ + L R +D P LA P+ P S SP P L
Sbjct: 1636 VHRRFLPFEALSRYAAQFRKSYDSLYPPLAEP------PKPPDGSLDSP-VPHLGPPFLV 1688
Query: 2616 RKLEEKASASPGENDSGTGGEEPQRDKRL----------------RTTITPEQLEILYQK 2659
+ E + +P E S GG P ++ RT T Q + L
Sbjct: 1689 PEPEAGGTRAPEER-SRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSF 1747
Query: 2660 YLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK-----GQFRAVGPAQAHRRCP 2714
+ + P ++ +A +GL RVV VWFQN R + RK G G C
Sbjct: 1748 FETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCR 1807
Query: 2715 FCRALFKAKTALEAHIR--------SRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFD 2766
C A F L H++ EA+R + ++ + GL+
Sbjct: 1808 RCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE------- 1860
Query: 2767 GTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFE--SPSMSSVNLN 2824
PP+ +G PL ELS + K G E E +PS S +
Sbjct: 1861 -------PPAGPEG---PLPEPPDGEELS-----QAEATKAGGKEPEEKATPSPSPAH-- 1903
Query: 2825 FDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMS 2884
D C +++ + D T + + S+ P L ++
Sbjct: 1904 ------TCDQC-AISFSSQDLLT-------SHRRLHFLPSLQPSAPPQ--LLDLPLLVFG 1947
Query: 2885 EYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRP 2944
E +++ P P K D S SP +GS G G+ P
Sbjct: 1948 ERNPLVAATSPMPGPPLKRKHEDG----------------SLSP--TGSEAGGGGEGEPP 1989
Query: 2945 GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKS 3004
KR RT + QL++L + PT + + ++GL KRVVQVWFQN RA+E+K
Sbjct: 1990 RDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKG 2049
Query: 3005 K 3005
+
Sbjct: 2050 Q 2050
Score = 71.2 bits (173), Expect = 2e-11
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 12/159 (7%)
Query: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPE 2651
A P+ A S ++ S+ ++L A + G GTG + +R RT ++
Sbjct: 2150 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSL 2209
Query: 2652 QLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGP----- 2706
QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2210 QLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGG 2269
Query: 2707 ------AQAHRRCPFCRALFKAKTALEAHIRSRHWHEAK 2739
A CP+C + + H+ SR H AK
Sbjct: 2270 SSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ-HLAK 2307
Score = 58.2 bits (139), Expect = 2e-07
Identities = 104/406 (25%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 2242 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK-N 2300
+R RT+ + QL++++ ++A P E E L + LP RVI VWFQNAR K +K
Sbjct: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2258
Query: 2301 YENQGEGKDGERRE--LTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKH---QKKLCYKDE 2355
+ G G E L R C C + + H ++ L E
Sbjct: 2259 LQGTAAGSTGGSSEGLLAAQR--------TDCPYCDVKYDFYVSCRGHLFSRQHLAKLKE 2310
Query: 2356 DEEGQDDSQNE--DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEA 2413
Q S+++ D A E + P + S P +A A + L+ A
Sbjct: 2311 AVRAQLKSESKCYDLAPAPE----APPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPA 2366
Query: 2414 ------EELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTP 2467
LA FNS A L A S P T + P L Q+ P+Q TNT
Sbjct: 2367 LAQPPLGNLAPFNSGPAA--SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ-TNTS 2423
Query: 2468 QQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLP-LKPLHTSTPQQLANLPPQ 2526
V P P P P + P+ S L LK L T+ P A L Q
Sbjct: 2424 TAGTTDPV--PGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVP---ALLGGQ 2478
Query: 2527 LIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLAS 2586
+P+ P + Q +F + M LF P NP++
Sbjct: 2479 FLPFPLPPAGGTAPPAVFGPQLQGAYF-------------QQLYGMKKGLF-PMNPMI-P 2523
Query: 2587 QLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSG 2632
Q L G +P P PT+T +L +PGE ++G
Sbjct: 2524 QTLIGLLPNALLQPPPQPPEPTATAPPKPPEL-----PAPGEGEAG 2564
Score = 53.5 bits (127), Expect = 4e-06
Identities = 52/210 (24%), Positives = 97/210 (46%), Gaps = 35/210 (16%)
Query: 2034 PQTPEPPPPPPPP--------------PPPPLPAAP-PQPASTP---AIPASAPPITSPT 2075
P PE P P PP P A P P PA T AI S+ + +
Sbjct: 1862 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 1921
Query: 2076 -----IAPAQPSVPLTQLSMPMELPIF---SPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127
+ QPS P L +P L +F +PL+ T P+ P + + G + P ++
Sbjct: 1922 RRLHFLPSLQPSAPPQLLDLP--LLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSE 1979
Query: 2128 LAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQK 2187
+ + ++KR RT I +QL +L +++ +++P+ + + ++++ GL ++
Sbjct: 1980 AGGGGEGE------PPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033
Query: 2188 VIKHWFRNTLFKERQ-RNKDSPYNFSNPPI 2216
V++ WF+NT +ER+ + + +P +P +
Sbjct: 2034 VVQVWFQNTRARERKGQFRSTPGGVPSPAV 2063
Score = 50.4 bits (119), Expect = 3e-05
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 30/171 (17%)
Query: 2037 PEPPPPP-----PPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091
P+P PP P P PPLP PP P S P P + + A + + L+ S
Sbjct: 2111 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSAS 2170
Query: 2092 MELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTR 2151
SP T +P +G +R RT+
Sbjct: 2171 SLAEPESPGAGGTSGGPGGGTGVPDGMG-------------------------QRRYRTQ 2205
Query: 2152 ITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQ 2202
++ QL++++ ++ +P+ ++ + + ++ GLP++VI+ WF+N KE++
Sbjct: 2206 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 21/105 (20%)
Query: 724 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAA 783
+P++C VC S T K L +H S HL+ M+ AA +
Sbjct: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKK---------------------AAIDPS 1361
Query: 784 ANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKH 828
A GAP T T ++C VC N + L IHM S H
Sbjct: 1362 APARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLH 1406
Score = 47.0 bits (110), Expect = 4e-04
Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ---PE---PTSSPDNKP- 1595
+PY+C VC S T K L +H S HL L + Q GQ PE P S+ D +P
Sbjct: 506 KPYRCDVCNYSTTTKGNLSIHMQSDKHLANL-QGFQAGPGGQGSPPEASLPPSAGDKEPK 564
Query: 1596 ----FKCNTCNVAYSQSSTLEIHMRSVLH 1620
++C C+ + S L IHM S H
Sbjct: 565 TKSSWQCKVCSYETNISRNLRIHMTSEKH 593
Score = 45.1 bits (105), Expect = 0.001
Identities = 72/308 (23%), Positives = 113/308 (36%), Gaps = 60/308 (19%)
Query: 61 LAESTASAGPPSEPASKEV-TCNECSASFASLQT---YMEHHCPSARPP--------PPL 108
L T S+ PS+P +K+ + S + S + +E C P P
Sbjct: 23 LPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEIGEPQEGPDC 82
Query: 109 REESASDTGEEGDEESDVE-------NLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGS 161
+D G E D+E + E +L+ + + G AY+V LS G
Sbjct: 83 GHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSL---------PGG 133
Query: 162 GSGPLPSLFLNSLP-GAGGKQGDPSCAAPVYP--QIINTFHIASSFGKWFEGPDQAFPNT 218
LP F P G G + +PS YP + HI F P Q F ++
Sbjct: 134 SELLLPKGF----PWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFD-----PIQGFSSS 184
Query: 219 SALAGLSPVLHSFRVFDVRHKSNKDYL---NSDGSAKSSCVSKDVPNNVDLSKFDGFVLY 275
+ S + RH + Y N G K + N+V +
Sbjct: 185 DQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAV--------- 235
Query: 276 GKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEP 335
+C LC+L F ++F+ H H + L+ + + LS A++Q + +
Sbjct: 236 -----FWLCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKA 287
Query: 336 LVSFLEPK 343
L+SFLEPK
Sbjct: 288 LISFLEPK 295
Score = 45.1 bits (105), Expect = 0.001
Identities = 81/389 (20%), Positives = 127/389 (32%), Gaps = 104/389 (26%)
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256
+++ ++++ + +Q PPA P P+ P D E++ + E G E P
Sbjct: 1845 EEEVEEEEVEEEQGLEPPAGPEGPLPEPP----------DGEELSQAEATKAGGKE--PE 1892
Query: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPY-----F 3311
K +P T + + + +L L + S P LL L +
Sbjct: 1893 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 1952
Query: 3312 VPGFSPYYAPQIPGALQSGYLQPM-----YGMEGLFPYSPALSQALMGLSPGSLLQQYQQ 3366
V SP P + + G L P G EG P L ++ P L Y+
Sbjct: 1953 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTIL---PEQLEILYRW 2009
Query: 3367 YQQ------SLQEAIQQQ--QQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP-------- 3410
Y Q + + I ++ ++++ Q Q + ++ K P G PSP
Sbjct: 2010 YMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATA 2069
Query: 3411 ---------------DKDPAKESPK----------------------PEEQKNTPREVSP 3433
D +E+PK P ++ TP P
Sbjct: 2070 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTP-EP 2128
Query: 3434 LLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQS 3493
LP LP P +E + P PK + AG + +A S
Sbjct: 2129 PLPLLPPPPPSEEEG------PEEPPKASPESEACSLSAGDLSDSSASS----------- 2171
Query: 3494 VVNLQEMVLHVPTGGGGGGSGGGGGGGGG 3522
L P G GG+ GG GGG G
Sbjct: 2172 --------LAEPESPGAGGTSGGPGGGTG 2192
Score = 40.4 bits (93), Expect = 0.033
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 26/115 (22%)
Query: 3119 QGIPPVLLPGLNSPSLPGFTPSNTALTSPK-------PNLMGLPSTTVPSPGLPTSGLPN 3171
QG+P L PGL P P P TSP P +G P T + PGL P+
Sbjct: 602 QGLPLGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR----PD 655
Query: 3172 KPSSASL-------------SSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPP 3213
KP A L PT A +++ PP Q + PPP
Sbjct: 656 KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPP 710
Score = 40.4 bits (93), Expect = 0.033
Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 433 GKDSGAAEGEKQEVGDGDCFSEKVEPA----EEEAEEEEEEEEAEEEEEEEEEEEEEEED 488
G +G A G ++ C E V +++ EEEEEE EEEEE EEEE EE+
Sbjct: 1797 GGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEE 1856
Query: 489 EG 490
+G
Sbjct: 1857 QG 1858
Score = 40.0 bits (92), Expect = 0.043
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 451 CFSEK-VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
C+ ++ +E EEEAE EEEEE EEEE EEE+ E G +G P D E
Sbjct: 1826 CYDDQTLEEEEEEAERGEEEEEVEEEE--VEEEQGLEPPAGPEGPLPEPPDGE 1876
Score = 38.5 bits (88), Expect = 0.13
Identities = 37/167 (22%), Positives = 56/167 (33%), Gaps = 14/167 (8%)
Query: 3396 PKASQTPVPPGAPSPDKDPAKESPKP---EEQKNTPREVSPLLPKLPEE--PEAESKSAD 3450
P +P P P PD +P P EE++ T E+ P + P K+ +
Sbjct: 1253 PGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1312
Query: 3451 SLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510
D F+ P YK C C+ F+ + H S V +L +M
Sbjct: 1313 FALDKFLDPARPYK--CTVCKESFTQKNILLVHYNS-------VSHLHKMKKAAIDPSAP 1363
Query: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRT 3557
G + C C + L H+ S LH+ R+
Sbjct: 1364 ARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRS 1410
Score = 37.4 bits (85), Expect = 0.28
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 12/97 (12%)
Query: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRA--LQES--ATGQPEPTSSPDNKPF---- 1596
++C +C K +H + H K + A L+E A G P P S D P+
Sbjct: 758 HRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVS 817
Query: 1597 ----KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629
+CN C+ + +++H R H+ ++ K+
Sbjct: 818 PLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKV 854
Score = 37.0 bits (84), Expect = 0.36
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 2232 EPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQ 2291
EPP+ + RT QL +L ++ ++ P + +S + L RV+ VWFQ
Sbjct: 1987 EPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
Query: 2292 NARQKARK 2299
N R + RK
Sbjct: 2041 NTRARERK 2048
Score = 35.0 bits (79), Expect = 1.4
Identities = 123/613 (20%), Positives = 197/613 (32%), Gaps = 136/613 (22%)
Query: 1572 KLKRALQESATG-QPEPTSSPDNKP-FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629
+L +A A G +PE ++P P C+ C +++S L H R LH
Sbjct: 1877 ELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRR--LHFLP------ 1928
Query: 1630 EAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVG 1689
SL S P + F NP A +P + E
Sbjct: 1929 ----------------SLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGS 1972
Query: 1690 MPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQ 1749
+ P G+ G E + K+L I Q + + Q ++ +++
Sbjct: 1973 LSPTGSEAGGG----GEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2028
Query: 1750 AQVQAHLQQELQQQAALIQSQLFN------------------PTLLPHFPMTTE-----T 1786
+ +Q Q A + F P LP F + T
Sbjct: 2029 GLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGT 2088
Query: 1787 LLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGP-GLLEDLKAQVQVPQQS 1845
+ +++ FP+ P+A P+ LP A T T P LL + +
Sbjct: 2089 GREAPKREAPAFPY--PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEE 2146
Query: 1846 HQQILPQQQQNQLSIAQ----SHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEG 1901
+ P+ + LS S S+L +P E A G G
Sbjct: 2147 PPKASPESEACSLSAGDLSDSSASSLAEP---------------------ESPGAGGTSG 2185
Query: 1902 NTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIAS---DARGNATKALLENFGFEL-- 1956
G +PD + + + ++ S L +I +A T E G E+
Sbjct: 2186 GPGGGTGVPDGMGQRRYR-------TQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2238
Query: 1957 ---VIQY-------NENKQKVQKKNGKTDQGEN-----LEKLECDSCGKLFSNILILKSH 2001
VIQ E K K+Q + G + ++ +C C + + + H
Sbjct: 2239 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298
Query: 2002 ---QEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP----PPPPPPPPPPLPAA 2054
++H+ +L+ + K Y L P PP PP P PL AA
Sbjct: 2299 LFSRQHL-------AKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAA 2351
Query: 2055 PPQPASTPAIPASAPPITSPTIAPAQP--SVPLTQLSMPMELPIFSPLMMQTMPLQTLPA 2112
P P P + S P + P + P S P + L + + ++ T +QT
Sbjct: 2352 PTLPRLAPVL-LSGPALAQPPLGNLAPFNSGPAASSGL---LGLATSVLPTTTVVQT--- 2404
Query: 2113 QLPPQLGPVEPLP 2125
GP PLP
Sbjct: 2405 -----AGPGRPLP 2412
Score = 35.0 bits (79), Expect = 1.4
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 2031 PLRPQT-----PEPPPPPPPPPPPPLPAAPPQPASTPA 2063
P+ PQT P PPP PP P APP+P PA
Sbjct: 2520 PMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPA 2557
Score = 34.7 bits (78), Expect = 1.8
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 9/103 (8%)
Query: 1483 EDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFL-DP 1541
E+ + EE+ EEE LE P G + + G E +A + G EK P
Sbjct: 1843 EEEEEVEEEEVEEEQGLE---PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSP 1899
Query: 1542 SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ 1584
S + C C SF+ +++L H LH L +LQ SA Q
Sbjct: 1900 SPAHTCDQCAISFSSQDLLTSH----RRLHFLP-SLQPSAPPQ 1937
Score = 33.9 bits (76), Expect = 3.1
Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 47/233 (20%)
Query: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDT-IGSQLD-KEKEYFDPATVRQLMAQQELD 3082
+CT+C + Y+ ++ H+ S H ++ + T S+++ E+ +P ++ + E+
Sbjct: 1383 KCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP---KEGETEGEVG 1439
Query: 3083 RIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPS--------- 3133
KK + G + F + P L+L +PA PPVL P P
Sbjct: 1440 TEKKGPDTSGFISGLP--FLSPPPPPLDLHR-FPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496
Query: 3134 --LPGFTPS-----NTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQA 3186
LP + L P P ++ LP+ T P P P + + P A+
Sbjct: 1497 LLLPFYLHDLKVGPKLTLAGPAP-VLSLPAATPPPPPQPPKA---ELAEREWERPPMAKE 1552
Query: 3187 TMAMGPQQPPQQQQQQ-------------------QQPQVQQPPPPPAAQPPP 3220
GP PP + Q + +Q PPP PPP
Sbjct: 1553 GNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPP 1605
Score = 33.5 bits (75), Expect = 4.0
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 13/92 (14%)
Query: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFS 2098
PP P PPPP P +TP P P A QP PL + + P+ +
Sbjct: 609 PPGLMGPGPPPP-------PGATPTSPPELFQYFGPQ-ALGQPQTPLAGPGLRPDKPLEA 660
Query: 2099 PLMMQTM-----PLQTLPAQLPPQLGPVEPLP 2125
L++ P + P P L P LP
Sbjct: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLP 692
Score = 33.1 bits (74), Expect = 5.3
Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 22/141 (15%)
Query: 2383 STP--MPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQP 2440
STP +PS A PA +A + F L + ++ G E PK EAP A P
Sbjct: 2053 STPGGVPSPAVKPPA-TATPASLPKFNLLLGKVDD--------GTGREAPK-REAP-AFP 2101
Query: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500
T P+P L P ++ TP + P LP LP PPP P++SP
Sbjct: 2102 YPTATLASGPQPFLP----PGKEATTPTPEPP----LPLLPPPPPSEEEGPEEPPKASPE 2153
Query: 2501 PSQLSHLPLKPLHTSTPQQLA 2521
S+ L L S+ LA
Sbjct: 2154 -SEACSLSAGDLSDSSASSLA 2173
Score = 32.7 bits (73), Expect = 6.9
Identities = 53/242 (21%), Positives = 79/242 (32%), Gaps = 38/242 (15%)
Query: 1247 SVQPM-LRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEK------------LIMTVTTPE 1293
SV P+ LRC +C N+K +QLH + K L+ TP
Sbjct: 815 SVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPS 874
Query: 1294 MVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLG--KNILPSASTE----------QS 1341
+ A D L+ P T E L ++IL + + ++
Sbjct: 875 RLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEA 934
Query: 1342 GDLKPSPADPGSVREDSGFICW----------KKGCNQVFKTSAALQTHFNEVHAKRPQL 1391
G+ +P DP E+ C KK + S L + L
Sbjct: 935 GNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPL 994
Query: 1392 PVSDRHVYKYRCNQCSLAFKTIEKLQLHS-QYHVIRAATMCCLCQRSFRTFQALKKHLET 1450
P+ VY C CS +++ H+ H ++ C LCQ AL HL
Sbjct: 995 PICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSH 1052
Query: 1451 SH 1452
H
Sbjct: 1053 LH 1054
Score = 32.7 bits (73), Expect = 6.9
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSP 2074
TPE P P P PP P +P+ +P P S P P
Sbjct: 1227 TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVP 1265
Score = 32.3 bits (72), Expect = 9.0
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Query: 2479 SLPQPPPQAPPPQC---PLPQSSPSPSQLSHLPLKPLHT-STPQQLANLPPQLIPYQCDQ 2534
+L QPPPQ P P P P P+P + + L T ST ++ + Y C Q
Sbjct: 2533 ALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHR---YLCRQ 2589
Query: 2535 CKLAFPSFEHWQEHQQ 2550
CK+AF HQ+
Sbjct: 2590 CKMAFDGEAPATAHQR 2605
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 531 bits (1369), Expect = e-150
Identities = 325/851 (38%), Positives = 455/851 (53%), Gaps = 103/851 (12%)
Query: 485 EEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSP---------L 535
+E DEGCK L S L+ +L RP + +SS ++ + + P L
Sbjct: 279 QEGDEGCKALI-SFLEPKLPARPSSD--IPLDNSSTVNMEANVAQTEDGPPEAEVQALIL 335
Query: 536 MPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESA 595
+ + LS + T++ S ++ + VA G D+ E
Sbjct: 336 LDEEVMALSPPSPPTATWDPSP----------------TQAKESPVAAGEAGPDWFPEGQ 379
Query: 596 NKDNATAPEPNESTE-GDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSR- 653
+D P N+S+ +GG +P +G E PS D +
Sbjct: 380 EEDGGLCPPLNQSSPTSKEGGTLP--------APVGSPEDPSDPPQPYRLADDYTPAPAA 431
Query: 654 ----SLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQP 709
SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE C YC +G
Sbjct: 432 FQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGA 491
Query: 710 HPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHT 769
HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q Q G G Q
Sbjct: 492 HPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQ----- 546
Query: 770 AGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHM 829
+ A++ S G +PKTK +W+C+VC YETN++RNLRIHMTSEKHM
Sbjct: 547 ---------GSPPEASLPPSAG---DKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHM 594
Query: 830 HNMMLLQQNMTQIQHNRHLGLGSLPSP-----AEAELYQYYLAQNMNLPNLKM------D 878
N+++L Q + +G G P P + EL+QY+ Q + P +
Sbjct: 595 QNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP 654
Query: 879 SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938
+AQ +++GF G A P G + D L QL+ +L S +
Sbjct: 655 DKPLEAQLLLNGFH--HVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 712
Query: 939 DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998
SLK+F+C VC F+TD+L++L H ++ RSL E EWK V GD+++CKLC Y TQLKAN
Sbjct: 713 SLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKAN 772
Query: 999 FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIG--------NPVHLKCNACDYYTN 1050
FQLH KTDKH QKYQL AH++EGG A ++G +P+HL+CN CD+ +N
Sbjct: 773 FQLHLKTDKHAQKYQLAAHLREGGGA-MGTPSPASLGDGAPYGSVSPLHLRCNICDFESN 831
Query: 1051 SLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSM 1110
S EK++LH + HE + ++YK E G+ YHC+LC + T ++L ++QH+R+
Sbjct: 832 SKEKMQLHARGAAHEENSQIYKVRLGAELGL------YHCLLCAWETPSRLAVLQHLRTP 885
Query: 1111 KHQRSESLRKLQRLQKGLPEEDEDLG---QIFTIRRCPSTDPEEAIEDVEGPSETAA-DP 1166
H+ +++ R+LQ LQ G P +E L I + P E + G S+ DP
Sbjct: 886 AHRDAQAQRRLQLLQNG-PTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDP 944
Query: 1167 EELAKDQEGGA------SSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPE 1220
E ++ G + +KE + A SK + GS P + RP I
Sbjct: 945 EGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGS--HPSLTLRPL---PICSL 999
Query: 1221 QMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPD 1280
Q+Y CPYC + + + +++R H ++QH+VQP RCPLCQ+ L + L HL+HLH+V P+
Sbjct: 1000 QVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPE 1059
Query: 1281 CVEKLIMTVTT 1291
CVEKL++ V+T
Sbjct: 1060 CVEKLLLVVST 1070
Score = 256 bits (655), Expect = 2e-67
Identities = 214/705 (30%), Positives = 297/705 (42%), Gaps = 192/705 (27%)
Query: 2910 GTVDYSETSSLADPCSPSPGASGSAGKSGDSG--DRPGQKRFRTQMTNLQLKVLKSCFND 2967
G + S SSLA+P SP G + S G G +G D GQ+R+RTQM++LQLK++K+C+
Sbjct: 2162 GDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220
Query: 2968 YRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKL---SMAKHFGINQTSYEGPKT 3024
YRTPTM ECEVLG +IGLPKRV+QVWFQNARAKEKK+KL + G ++ +T
Sbjct: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280
Query: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRI 3084
+C C +KY +S R H+FS+QH++K+K+ + +QL E + +D L E
Sbjct: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYD------LAPAPEAPPA 2334
Query: 3085 KKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLL--PGLNSPSLPGFTPSNT 3142
KA A+ G A P L + PVLL P L P L P N+
Sbjct: 2335 LKAPPATTPASMPLG--------------AAPTLPRLAPVLLSGPALAQPPLGNLAPFNS 2380
Query: 3143 ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQ 3202
+ L+GL ++ +P+ + + P +P PQ+P Q
Sbjct: 2381 G-PAASSGLLGLATSVLPTTTVVQTAGPGRPL-----------------PQRPMPDQTNT 2422
Query: 3203 QQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKG 3262
P P P +P +KV + K P+ P
Sbjct: 2423 STAGTTDPVPGPPTEPL-----------------GDKVSSERK-------PVAGPTSSSN 2458
Query: 3263 EAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQ 3322
+A L+ L+A T+ P ALL QFLP+ +P P
Sbjct: 2459 DA-----------------------LKNLKALKTTVP-ALLGGQFLPFPLPPAGGTAPPA 2494
Query: 3323 IPG-ALQSGYLQPMYGM-EGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQ 3380
+ G LQ Y Q +YGM +GLFP +P + Q L+GL P +LLQ
Sbjct: 2495 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ------------------ 2536
Query: 3381 RQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPE 3440
PP P P + A PKP P+LP
Sbjct: 2537 -----------------------PP--PQPPEPTATAPPKP--------------PELPA 2557
Query: 3441 EPEAESKSADSLY---DPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNL 3497
E E+ D L V ++ +CR+C+ F E A +H +S CFFG+
Sbjct: 2558 PGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGS 2617
Query: 3498 QEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHR- 3556
L VP +YHCLACE L G EAL+ HL S+ H+ +
Sbjct: 2618 MPPPLRVPI--------------------CTYHCLACEVLLSGREALASHLRSSAHRRKA 2657
Query: 3557 ---------TITRAARNAK------EHPSLLPHSACFPDPSTAST 3586
+IT AA A + + LPH+ P +T ST
Sbjct: 2658 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702
Score = 169 bits (427), Expect = 6e-41
Identities = 111/264 (42%), Positives = 150/264 (56%), Gaps = 40/264 (15%)
Query: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500
+QT E++ + +++E+ E++ +Q L +PP P+ PLP+ P
Sbjct: 1829 DQTLEEEEEEAERGEEEEEVEEEEVEEEQGL----------EPPAG---PEGPLPEP-PD 1874
Query: 2501 PSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQF 2560
+LS P++ A P + CDQC ++F S + H++LHFL +
Sbjct: 1875 GEELSQAEATKAGGKEPEEKATPSPSPA-HTCDQCAISFSSQDLLTSHRRLHFLPSLQPS 1933
Query: 2561 IHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEE 2620
PQ LD +P ++F NPL+A+ ++ P P LKRK E+
Sbjct: 1934 APPQLLD----LPLLVFGERNPLVAA-------------TSPMPGPP------LKRKHED 1970
Query: 2621 KASASPGENDSGTGGE-EPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVG 2679
S SP +++G GGE EP RDKRLRTTI PEQLEILY+ Y+ DSNPTRKMLD I+ EVG
Sbjct: 1971 -GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVG 2029
Query: 2680 LKKRVVQVWFQNTRARERKGQFRA 2703
LKKRVVQVWFQNTRARERKGQFR+
Sbjct: 2030 LKKRVVQVWFQNTRARERKGQFRS 2053
Score = 164 bits (414), Expect = 2e-39
Identities = 176/722 (24%), Positives = 273/722 (37%), Gaps = 207/722 (28%)
Query: 1489 VEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRA-----LPFRKGPNFTMEKFLDPSR 1543
V E + D+ + + G+ E +EP A L +RK NF ++KFLDP+R
Sbjct: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPAR 1323
Query: 1544 PYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNV 1603
P+KC C
Sbjct: 1324 ---------------------------------------------------PYKCTVCKE 1332
Query: 1604 AYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTF 1663
+++Q + L +H SV H K + A ++ ++ + G + + ++ P +
Sbjct: 1333 SFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCR---- 1388
Query: 1664 TTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQ 1723
+ N SS ++L Q + G + I P R
Sbjct: 1389 VSYNQSSTLEIHMRSVLHQTRSR-------GTKTDSKIEGPE----------------RS 1425
Query: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMT 1783
Q++ ++ + + + +++ + + + + LF P +LP FP+
Sbjct: 1426 QEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLV 1485
Query: 1784 TETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQ 1843
E+LL+LQQQQ LL PFY+ + ++ P+ LTL G P L L A P
Sbjct: 1486 PESLLKLQQQQ-LLLPFYLH--DLKVGPK---------LTLAGPAPVL--SLPAATPPPP 1531
Query: 1844 QSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNT 1903
PQ + +L+ E+E +R + EG E
Sbjct: 1532 -------PQPPKAELA--------------------------EREWERPPMAKEGNEAG- 1557
Query: 1904 GPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNEN 1963
PS P + ++A A KALLENFGFELVIQYNE
Sbjct: 1558 -------------------------PSSPPDPLPNEAARTAAKALLENFGFELVIQYNEG 1592
Query: 1964 KQKVQKKNGKTDQGENL---EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAK 2020
KQ V E L +KL C +CGKLFSN+LILK+H+EHVH+ + PF+ L R+A
Sbjct: 1593 KQAVPPPPTPPPP-EALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAA 1651
Query: 2021 QYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ 2080
Q+R YD LY P EPP PP P+P P P P P T AP +
Sbjct: 1652 QFRKSYDSLY---PPLAEPPKPPDGSLDSPVPHLGP-PFLVP------EPEAGGTRAPEE 1701
Query: 2081 PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTL 2140
S + E ++ LPP L
Sbjct: 1702 RSRAGGHWPIEEE--------------ESSRGNLPP-----------------------L 1724
Query: 2141 LQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKE 2200
+ + RT+ T+ Q + L+ +F+ + P + +++ +A GL +V+ WF+N K
Sbjct: 1725 VPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKA 1784
Query: 2201 RQ 2202
R+
Sbjct: 1785 RK 1786
Score = 114 bits (284), Expect = 2e-24
Identities = 129/504 (25%), Positives = 189/504 (37%), Gaps = 100/504 (19%)
Query: 2042 PPPPPPPPPLPAA------PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095
PPPPP PP A PP S+PP P A + L + + EL
Sbjct: 1528 PPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE-NFGFELV 1586
Query: 2096 IFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA-QLYQHQLNPTLLQQQNKRPRTRITD 2154
I Q +P P P LG + L +L+ + L +L+ + R
Sbjct: 1587 IQYNEGKQAVPPPPTPPP-PEALGGGDKLACGACGKLFSNML---ILKTHEEHVHRRFLP 1642
Query: 2155 DQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNP 2214
L +Y + +A+ P + DSP P
Sbjct: 1643 --FEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSL----------------DSPVPHLGP 1684
Query: 2215 PITSLEELKIDSRPPSPEPPKQEYW-----------------GSKRSSRTRFTDYQLRVL 2257
P E +R P +W +R SRT+FT++Q + L
Sbjct: 1685 PFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQAL 1744
Query: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTN 2317
Q FF+ +AYPKD E E+L++LL L +RV+VVWFQNARQKARKN G G +
Sbjct: 1745 QSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGAS 1804
Query: 2318 DRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD----EDEEGQDDSQNEDSMDAME 2373
C++C F +F+L++H KK CY D E+EE + + E+ ++ E
Sbjct: 1805 G-----------CRRCHATFSCVFELVRHLKK-CYDDQTLEEEEEEAERGEEEEEVEEEE 1852
Query: 2374 ILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLA 2433
+ P P P + EEL+ + T+AG ++P+
Sbjct: 1853 VEEEQGLE-----PPAGPEGPLPE------------PPDGEELSQAEA-TKAGGKEPEEK 1894
Query: 2434 EAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP 2493
PS P T ++ + + Q L L LP P APP
Sbjct: 1895 ATPSPSPAHTCDQCA--------------ISFSSQDLLTSHRRLHFLPSLQPSAPPQLLD 1940
Query: 2494 LP-----QSSPSPSQLSHLPLKPL 2512
LP + +P + S +P PL
Sbjct: 1941 LPLLVFGERNPLVAATSPMPGPPL 1964
Score = 76.6 bits (187), Expect = 4e-13
Identities = 138/601 (22%), Positives = 205/601 (34%), Gaps = 139/601 (23%)
Query: 2474 LVSLPSL-PQPPPQAP-----------PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLA 2521
++SLP+ P PPPQ P PP + S LP + T+ L
Sbjct: 1520 VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE 1579
Query: 2522 N---------------LPPQLIP-----------YQCDQCKLAFPSFEHWQEHQQLHFLS 2555
N +PP P C C F + + H++
Sbjct: 1580 NFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEE----H 1635
Query: 2556 AQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLK 2615
+F+ + L R +D P LA P+ P S SP P L
Sbjct: 1636 VHRRFLPFEALSRYAAQFRKSYDSLYPPLAEP------PKPPDGSLDSP-VPHLGPPFLV 1688
Query: 2616 RKLEEKASASPGENDSGTGGEEPQRDKRL----------------RTTITPEQLEILYQK 2659
+ E + +P E S GG P ++ RT T Q + L
Sbjct: 1689 PEPEAGGTRAPEER-SRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSF 1747
Query: 2660 YLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK-----GQFRAVGPAQAHRRCP 2714
+ + P ++ +A +GL RVV VWFQN R + RK G G C
Sbjct: 1748 FETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCR 1807
Query: 2715 FCRALFKAKTALEAHIR--------SRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFD 2766
C A F L H++ EA+R + ++ + GL+
Sbjct: 1808 RCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE------- 1860
Query: 2767 GTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFE--SPSMSSVNLN 2824
PP+ +G PL ELS + K G E E +PS S +
Sbjct: 1861 -------PPAGPEG---PLPEPPDGEELS-----QAEATKAGGKEPEEKATPSPSPAH-- 1903
Query: 2825 FDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMS 2884
D C +++ + D T + + S+ P L ++
Sbjct: 1904 ------TCDQC-AISFSSQDLLT-------SHRRLHFLPSLQPSAPPQ--LLDLPLLVFG 1947
Query: 2885 EYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRP 2944
E +++ P P K D S SP +GS G G+ P
Sbjct: 1948 ERNPLVAATSPMPGPPLKRKHEDG----------------SLSP--TGSEAGGGGEGEPP 1989
Query: 2945 GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKS 3004
KR RT + QL++L + PT + + ++GL KRVVQVWFQN RA+E+K
Sbjct: 1990 RDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKG 2049
Query: 3005 K 3005
+
Sbjct: 2050 Q 2050
Score = 71.2 bits (173), Expect = 2e-11
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 12/159 (7%)
Query: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPE 2651
A P+ A S ++ S+ ++L A + G GTG + +R RT ++
Sbjct: 2150 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSL 2209
Query: 2652 QLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGP----- 2706
QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2210 QLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGG 2269
Query: 2707 ------AQAHRRCPFCRALFKAKTALEAHIRSRHWHEAK 2739
A CP+C + + H+ SR H AK
Sbjct: 2270 SSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ-HLAK 2307
Score = 58.2 bits (139), Expect = 2e-07
Identities = 104/406 (25%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 2242 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK-N 2300
+R RT+ + QL++++ ++A P E E L + LP RVI VWFQNAR K +K
Sbjct: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2258
Query: 2301 YENQGEGKDGERRE--LTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKH---QKKLCYKDE 2355
+ G G E L R C C + + H ++ L E
Sbjct: 2259 LQGTAAGSTGGSSEGLLAAQR--------TDCPYCDVKYDFYVSCRGHLFSRQHLAKLKE 2310
Query: 2356 DEEGQDDSQNE--DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEA 2413
Q S+++ D A E + P + S P +A A + L+ A
Sbjct: 2311 AVRAQLKSESKCYDLAPAPE----APPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPA 2366
Query: 2414 ------EELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTP 2467
LA FNS A L A S P T + P L Q+ P+Q TNT
Sbjct: 2367 LAQPPLGNLAPFNSGPAA--SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ-TNTS 2423
Query: 2468 QQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLP-LKPLHTSTPQQLANLPPQ 2526
V P P P P + P+ S L LK L T+ P A L Q
Sbjct: 2424 TAGTTDPV--PGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVP---ALLGGQ 2478
Query: 2527 LIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLAS 2586
+P+ P + Q +F + M LF P NP++
Sbjct: 2479 FLPFPLPPAGGTAPPAVFGPQLQGAYF-------------QQLYGMKKGLF-PMNPMI-P 2523
Query: 2587 QLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSG 2632
Q L G +P P PT+T +L +PGE ++G
Sbjct: 2524 QTLIGLLPNALLQPPPQPPEPTATAPPKPPEL-----PAPGEGEAG 2564
Score = 53.5 bits (127), Expect = 4e-06
Identities = 52/210 (24%), Positives = 97/210 (46%), Gaps = 35/210 (16%)
Query: 2034 PQTPEPPPPPPPP--------------PPPPLPAAP-PQPASTP---AIPASAPPITSPT 2075
P PE P P PP P A P P PA T AI S+ + +
Sbjct: 1862 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 1921
Query: 2076 -----IAPAQPSVPLTQLSMPMELPIF---SPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127
+ QPS P L +P L +F +PL+ T P+ P + + G + P ++
Sbjct: 1922 RRLHFLPSLQPSAPPQLLDLP--LLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSE 1979
Query: 2128 LAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQK 2187
+ + ++KR RT I +QL +L +++ +++P+ + + ++++ GL ++
Sbjct: 1980 AGGGGEGE------PPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033
Query: 2188 VIKHWFRNTLFKERQ-RNKDSPYNFSNPPI 2216
V++ WF+NT +ER+ + + +P +P +
Sbjct: 2034 VVQVWFQNTRARERKGQFRSTPGGVPSPAV 2063
Score = 50.4 bits (119), Expect = 3e-05
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 30/171 (17%)
Query: 2037 PEPPPPP-----PPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091
P+P PP P P PPLP PP P S P P + + A + + L+ S
Sbjct: 2111 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSAS 2170
Query: 2092 MELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTR 2151
SP T +P +G +R RT+
Sbjct: 2171 SLAEPESPGAGGTSGGPGGGTGVPDGMG-------------------------QRRYRTQ 2205
Query: 2152 ITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQ 2202
++ QL++++ ++ +P+ ++ + + ++ GLP++VI+ WF+N KE++
Sbjct: 2206 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 21/105 (20%)
Query: 724 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAA 783
+P++C VC S T K L +H S HL+ M+ AA +
Sbjct: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKK---------------------AAIDPS 1361
Query: 784 ANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKH 828
A GAP T T ++C VC N + L IHM S H
Sbjct: 1362 APARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLH 1406
Score = 47.0 bits (110), Expect = 4e-04
Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ---PE---PTSSPDNKP- 1595
+PY+C VC S T K L +H S HL L + Q GQ PE P S+ D +P
Sbjct: 506 KPYRCDVCNYSTTTKGNLSIHMQSDKHLANL-QGFQAGPGGQGSPPEASLPPSAGDKEPK 564
Query: 1596 ----FKCNTCNVAYSQSSTLEIHMRSVLH 1620
++C C+ + S L IHM S H
Sbjct: 565 TKSSWQCKVCSYETNISRNLRIHMTSEKH 593
Score = 45.1 bits (105), Expect = 0.001
Identities = 72/308 (23%), Positives = 113/308 (36%), Gaps = 60/308 (19%)
Query: 61 LAESTASAGPPSEPASKEV-TCNECSASFASLQT---YMEHHCPSARPP--------PPL 108
L T S+ PS+P +K+ + S + S + +E C P P
Sbjct: 23 LPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEIGEPQEGPDC 82
Query: 109 REESASDTGEEGDEESDVE-------NLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGS 161
+D G E D+E + E +L+ + + G AY+V LS G
Sbjct: 83 GHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSL---------PGG 133
Query: 162 GSGPLPSLFLNSLP-GAGGKQGDPSCAAPVYP--QIINTFHIASSFGKWFEGPDQAFPNT 218
LP F P G G + +PS YP + HI F P Q F ++
Sbjct: 134 SELLLPKGF----PWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFD-----PIQGFSSS 184
Query: 219 SALAGLSPVLHSFRVFDVRHKSNKDYL---NSDGSAKSSCVSKDVPNNVDLSKFDGFVLY 275
+ S + RH + Y N G K + N+V +
Sbjct: 185 DQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAV--------- 235
Query: 276 GKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEP 335
+C LC+L F ++F+ H H + L+ + + LS A++Q + +
Sbjct: 236 -----FWLCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKA 287
Query: 336 LVSFLEPK 343
L+SFLEPK
Sbjct: 288 LISFLEPK 295
Score = 45.1 bits (105), Expect = 0.001
Identities = 81/389 (20%), Positives = 127/389 (32%), Gaps = 104/389 (26%)
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256
+++ ++++ + +Q PPA P P+ P D E++ + E G E P
Sbjct: 1845 EEEVEEEEVEEEQGLEPPAGPEGPLPEPP----------DGEELSQAEATKAGGKE--PE 1892
Query: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPY-----F 3311
K +P T + + + +L L + S P LL L +
Sbjct: 1893 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 1952
Query: 3312 VPGFSPYYAPQIPGALQSGYLQPM-----YGMEGLFPYSPALSQALMGLSPGSLLQQYQQ 3366
V SP P + + G L P G EG P L ++ P L Y+
Sbjct: 1953 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTIL---PEQLEILYRW 2009
Query: 3367 YQQ------SLQEAIQQQ--QQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP-------- 3410
Y Q + + I ++ ++++ Q Q + ++ K P G PSP
Sbjct: 2010 YMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATA 2069
Query: 3411 ---------------DKDPAKESPK----------------------PEEQKNTPREVSP 3433
D +E+PK P ++ TP P
Sbjct: 2070 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTP-EP 2128
Query: 3434 LLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQS 3493
LP LP P +E + P PK + AG + +A S
Sbjct: 2129 PLPLLPPPPPSEEEG------PEEPPKASPESEACSLSAGDLSDSSASS----------- 2171
Query: 3494 VVNLQEMVLHVPTGGGGGGSGGGGGGGGG 3522
L P G GG+ GG GGG G
Sbjct: 2172 --------LAEPESPGAGGTSGGPGGGTG 2192
Score = 40.4 bits (93), Expect = 0.033
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 26/115 (22%)
Query: 3119 QGIPPVLLPGLNSPSLPGFTPSNTALTSPK-------PNLMGLPSTTVPSPGLPTSGLPN 3171
QG+P L PGL P P P TSP P +G P T + PGL P+
Sbjct: 602 QGLPLGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR----PD 655
Query: 3172 KPSSASL-------------SSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPP 3213
KP A L PT A +++ PP Q + PPP
Sbjct: 656 KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPP 710
Score = 40.4 bits (93), Expect = 0.033
Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 433 GKDSGAAEGEKQEVGDGDCFSEKVEPA----EEEAEEEEEEEEAEEEEEEEEEEEEEEED 488
G +G A G ++ C E V +++ EEEEEE EEEEE EEEE EE+
Sbjct: 1797 GGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEE 1856
Query: 489 EG 490
+G
Sbjct: 1857 QG 1858
Score = 40.0 bits (92), Expect = 0.043
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 451 CFSEK-VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
C+ ++ +E EEEAE EEEEE EEEE EEE+ E G +G P D E
Sbjct: 1826 CYDDQTLEEEEEEAERGEEEEEVEEEE--VEEEQGLEPPAGPEGPLPEPPDGE 1876
Score = 38.5 bits (88), Expect = 0.13
Identities = 37/167 (22%), Positives = 56/167 (33%), Gaps = 14/167 (8%)
Query: 3396 PKASQTPVPPGAPSPDKDPAKESPKP---EEQKNTPREVSPLLPKLPEE--PEAESKSAD 3450
P +P P P PD +P P EE++ T E+ P + P K+ +
Sbjct: 1253 PGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1312
Query: 3451 SLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510
D F+ P YK C C+ F+ + H S V +L +M
Sbjct: 1313 FALDKFLDPARPYK--CTVCKESFTQKNILLVHYNS-------VSHLHKMKKAAIDPSAP 1363
Query: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRT 3557
G + C C + L H+ S LH+ R+
Sbjct: 1364 ARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRS 1410
Score = 37.4 bits (85), Expect = 0.28
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 12/97 (12%)
Query: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRA--LQES--ATGQPEPTSSPDNKPF---- 1596
++C +C K +H + H K + A L+E A G P P S D P+
Sbjct: 758 HRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVS 817
Query: 1597 ----KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629
+CN C+ + +++H R H+ ++ K+
Sbjct: 818 PLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKV 854
Score = 37.0 bits (84), Expect = 0.36
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 2232 EPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQ 2291
EPP+ + RT QL +L ++ ++ P + +S + L RV+ VWFQ
Sbjct: 1987 EPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
Query: 2292 NARQKARK 2299
N R + RK
Sbjct: 2041 NTRARERK 2048
Score = 35.0 bits (79), Expect = 1.4
Identities = 123/613 (20%), Positives = 197/613 (32%), Gaps = 136/613 (22%)
Query: 1572 KLKRALQESATG-QPEPTSSPDNKP-FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629
+L +A A G +PE ++P P C+ C +++S L H R LH
Sbjct: 1877 ELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRR--LHFLP------ 1928
Query: 1630 EAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVG 1689
SL S P + F NP A +P + E
Sbjct: 1929 ----------------SLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGS 1972
Query: 1690 MPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQ 1749
+ P G+ G E + K+L I Q + + Q ++ +++
Sbjct: 1973 LSPTGSEAGGG----GEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2028
Query: 1750 AQVQAHLQQELQQQAALIQSQLFN------------------PTLLPHFPMTTE-----T 1786
+ +Q Q A + F P LP F + T
Sbjct: 2029 GLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGT 2088
Query: 1787 LLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGP-GLLEDLKAQVQVPQQS 1845
+ +++ FP+ P+A P+ LP A T T P LL + +
Sbjct: 2089 GREAPKREAPAFPY--PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEE 2146
Query: 1846 HQQILPQQQQNQLSIAQ----SHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEG 1901
+ P+ + LS S S+L +P E A G G
Sbjct: 2147 PPKASPESEACSLSAGDLSDSSASSLAEP---------------------ESPGAGGTSG 2185
Query: 1902 NTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIAS---DARGNATKALLENFGFEL-- 1956
G +PD + + + ++ S L +I +A T E G E+
Sbjct: 2186 GPGGGTGVPDGMGQRRYR-------TQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2238
Query: 1957 ---VIQY-------NENKQKVQKKNGKTDQGEN-----LEKLECDSCGKLFSNILILKSH 2001
VIQ E K K+Q + G + ++ +C C + + + H
Sbjct: 2239 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298
Query: 2002 ---QEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP----PPPPPPPPPPLPAA 2054
++H+ +L+ + K Y L P PP PP P PL AA
Sbjct: 2299 LFSRQHL-------AKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAA 2351
Query: 2055 PPQPASTPAIPASAPPITSPTIAPAQP--SVPLTQLSMPMELPIFSPLMMQTMPLQTLPA 2112
P P P + S P + P + P S P + L + + ++ T +QT
Sbjct: 2352 PTLPRLAPVL-LSGPALAQPPLGNLAPFNSGPAASSGL---LGLATSVLPTTTVVQT--- 2404
Query: 2113 QLPPQLGPVEPLP 2125
GP PLP
Sbjct: 2405 -----AGPGRPLP 2412
Score = 35.0 bits (79), Expect = 1.4
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 2031 PLRPQT-----PEPPPPPPPPPPPPLPAAPPQPASTPA 2063
P+ PQT P PPP PP P APP+P PA
Sbjct: 2520 PMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPA 2557
Score = 34.7 bits (78), Expect = 1.8
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 9/103 (8%)
Query: 1483 EDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFL-DP 1541
E+ + EE+ EEE LE P G + + G E +A + G EK P
Sbjct: 1843 EEEEEVEEEEVEEEQGLE---PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSP 1899
Query: 1542 SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ 1584
S + C C SF+ +++L H LH L +LQ SA Q
Sbjct: 1900 SPAHTCDQCAISFSSQDLLTSH----RRLHFLP-SLQPSAPPQ 1937
Score = 33.9 bits (76), Expect = 3.1
Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 47/233 (20%)
Query: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDT-IGSQLD-KEKEYFDPATVRQLMAQQELD 3082
+CT+C + Y+ ++ H+ S H ++ + T S+++ E+ +P ++ + E+
Sbjct: 1383 KCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP---KEGETEGEVG 1439
Query: 3083 RIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPS--------- 3133
KK + G + F + P L+L +PA PPVL P P
Sbjct: 1440 TEKKGPDTSGFISGLP--FLSPPPPPLDLHR-FPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496
Query: 3134 --LPGFTPS-----NTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQA 3186
LP + L P P ++ LP+ T P P P + + P A+
Sbjct: 1497 LLLPFYLHDLKVGPKLTLAGPAP-VLSLPAATPPPPPQPPKA---ELAEREWERPPMAKE 1552
Query: 3187 TMAMGPQQPPQQQQQQ-------------------QQPQVQQPPPPPAAQPPP 3220
GP PP + Q + +Q PPP PPP
Sbjct: 1553 GNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPP 1605
Score = 33.5 bits (75), Expect = 4.0
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 13/92 (14%)
Query: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFS 2098
PP P PPPP P +TP P P A QP PL + + P+ +
Sbjct: 609 PPGLMGPGPPPP-------PGATPTSPPELFQYFGPQ-ALGQPQTPLAGPGLRPDKPLEA 660
Query: 2099 PLMMQTM-----PLQTLPAQLPPQLGPVEPLP 2125
L++ P + P P L P LP
Sbjct: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLP 692
Score = 33.1 bits (74), Expect = 5.3
Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 22/141 (15%)
Query: 2383 STP--MPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQP 2440
STP +PS A PA +A + F L + ++ G E PK EAP A P
Sbjct: 2053 STPGGVPSPAVKPPA-TATPASLPKFNLLLGKVDD--------GTGREAPK-REAP-AFP 2101
Query: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500
T P+P L P ++ TP + P LP LP PPP P++SP
Sbjct: 2102 YPTATLASGPQPFLP----PGKEATTPTPEPP----LPLLPPPPPSEEEGPEEPPKASPE 2153
Query: 2501 PSQLSHLPLKPLHTSTPQQLA 2521
S+ L L S+ LA
Sbjct: 2154 -SEACSLSAGDLSDSSASSLA 2173
Score = 32.7 bits (73), Expect = 6.9
Identities = 53/242 (21%), Positives = 79/242 (32%), Gaps = 38/242 (15%)
Query: 1247 SVQPM-LRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEK------------LIMTVTTPE 1293
SV P+ LRC +C N+K +QLH + K L+ TP
Sbjct: 815 SVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPS 874
Query: 1294 MVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLG--KNILPSASTE----------QS 1341
+ A D L+ P T E L ++IL + + ++
Sbjct: 875 RLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEA 934
Query: 1342 GDLKPSPADPGSVREDSGFICW----------KKGCNQVFKTSAALQTHFNEVHAKRPQL 1391
G+ +P DP E+ C KK + S L + L
Sbjct: 935 GNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPL 994
Query: 1392 PVSDRHVYKYRCNQCSLAFKTIEKLQLHS-QYHVIRAATMCCLCQRSFRTFQALKKHLET 1450
P+ VY C CS +++ H+ H ++ C LCQ AL HL
Sbjct: 995 PICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSH 1052
Query: 1451 SH 1452
H
Sbjct: 1053 LH 1054
Score = 32.7 bits (73), Expect = 6.9
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSP 2074
TPE P P P PP P +P+ +P P S P P
Sbjct: 1227 TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVP 1265
Score = 32.3 bits (72), Expect = 9.0
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Query: 2479 SLPQPPPQAPPPQC---PLPQSSPSPSQLSHLPLKPLHT-STPQQLANLPPQLIPYQCDQ 2534
+L QPPPQ P P P P P+P + + L T ST ++ + Y C Q
Sbjct: 2533 ALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHR---YLCRQ 2589
Query: 2535 CKLAFPSFEHWQEHQQ 2550
CK+AF HQ+
Sbjct: 2590 CKMAFDGEAPATAHQR 2605
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 86.3 bits (212), Expect = 5e-16
Identities = 104/409 (25%), Positives = 152/409 (37%), Gaps = 48/409 (11%)
Query: 1723 QQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPM 1782
QQQQQ QQ+ Q+ Q Q Q + +Q Q QQ Q Q Q + P PM
Sbjct: 273 QQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPM 332
Query: 1783 TTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVP 1842
Q QQQ HL P Y +P P + + L G +
Sbjct: 333 MQHLQEQQQQQMHLQPPSY------HRDPHQYTPEQAHTVQLIPLG-----------SMS 375
Query: 1843 QQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGN 1902
Q +Q+ PQQ + QSH SQH ++++ + K S R+ + G+
Sbjct: 376 QYYYQE--PQQPYSHPLYQQSHL-----SQHQQREDSQL---KTYSSDRQAQAMLSSHGD 425
Query: 1903 TGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELV----- 1957
GP +T + + ++ P + P I + G + L + + +
Sbjct: 426 LGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDG 485
Query: 1958 -IQYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSNILILKSH-QEHVHQNYFPFKQL 2015
Q + Q K +Q + KL C C K F N+ L H + H P +
Sbjct: 486 RAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQ 545
Query: 2016 ERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPAS-TPAI-PASAPPITS 2073
E K + P P+PP PPPPPPPPP P PP+ S TP + P S P
Sbjct: 546 EEGEK-----------VLPPQPQPPLPPPPPPPPP-PQLPPEAESLTPMVMPVSVPVKLL 593
Query: 2074 PTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVE 2122
P +Q T + S + MP+ +P + P + E
Sbjct: 594 PPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAE 642
Score = 41.2 bits (95), Expect = 0.019
Identities = 81/340 (23%), Positives = 120/340 (35%), Gaps = 52/340 (15%)
Query: 2427 DEKPKLAEAP--SAQPNQTQEKQGQPKPELQQQEQ--PEQKTNTPQQKL--------PQL 2474
D + LA+ P QP Q + Q ++QQ + P+Q+ QQ++ PQ
Sbjct: 235 DYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294
Query: 2475 VSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQ 2534
+ PS PQPPPQ PQ Q Q+ P + + +L Q Q Q
Sbjct: 295 IR-PSQPQPPPQQQQPQQLQLQQRQGSMQI------PQYYQPQPMMQHLQEQ----QQQQ 343
Query: 2535 CKLAFPSFE---HWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSG 2591
L PS+ H +Q H + Q+ + P+ S+PL LS
Sbjct: 344 MHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPY-----SHPLYQQSHLS- 397
Query: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASP----GENDSGTGGEEPQRDKRLRTT 2647
S + T + +A S G D+G G R+ +T
Sbjct: 398 ----------QHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSST 447
Query: 2648 ITPEQLEILYQKYLLDSNPTRKMLDHIA--HEVGLKKRVVQVWFQNTRARERKGQFRAVG 2705
+ L +L + P + L A ++ L Q + + + KG F
Sbjct: 448 LPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPES-SGQPKGAFGEQF 506
Query: 2706 PAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNL 2745
A+ C C FK AL H+RS H RA NL
Sbjct: 507 DAKNKLTCSICLKEFKNLPALNGHMRS---HGGMRASPNL 543
Score = 40.0 bits (92), Expect = 0.043
Identities = 81/379 (21%), Positives = 129/379 (34%), Gaps = 65/379 (17%)
Query: 3144 LTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQ 3203
L S KP M P+ +PS P+ + LS P + +G Q P Q
Sbjct: 184 LLSQKP--MEPPAPAIPSRYQQVPQQPHPGFTGGLSKPA-----LQVG-QHPTQGHLYYD 235
Query: 3204 QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGE 3263
Q P QP PQ+ Q QQ + +++++A + + + +E
Sbjct: 236 YQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQR-----ISMQEIQT 290
Query: 3264 APTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQI 3323
P + P P + P QLQ Q + Q Y+ P P
Sbjct: 291 QPQQIRPSQPQPPPQQQ---QPQQLQLQQRQGSM--------QIPQYYQP--QPMMQHLQ 337
Query: 3324 PGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQ----------YQQSLQE 3373
Q +LQP Y+P + + + GS+ Q Y Q YQQS
Sbjct: 338 EQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLS 397
Query: 3374 AIQQQQQRQLQQQQQQKVQQQQPKASQTPVPP----GAPSPDKDPAKESPKPEEQKNTP- 3428
QQ++ QL+ + Q + PP G P+ S P +P
Sbjct: 398 QHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPS 457
Query: 3429 -----------REVSP--LLPKL--------PEEPEAESKSADSLYDPFIVPKVQYKLVC 3467
+++SP + P++ P PE+ + + + F + KL C
Sbjct: 458 GIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQF---DAKNKLTC 514
Query: 3468 RKCQAGFSDEEAARSHLKS 3486
C F + A H++S
Sbjct: 515 SICLKEFKNLPALNGHMRS 533
Score = 35.8 bits (81), Expect = 0.81
Identities = 18/45 (40%), Positives = 24/45 (53%)
Query: 441 GEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEE 485
G K + + V EEE EEEEEE+ EE+ + +EEE E
Sbjct: 938 GRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESE 982
Score = 35.0 bits (79), Expect = 1.4
Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 15/66 (22%)
Query: 2452 PELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP------LPQSSPSPSQLS 2505
P L+Q+E +K PQ PQ P LP PPP PPPQ P P P +
Sbjct: 541 PNLKQEEG--EKVLPPQ---PQ----PPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVK 591
Query: 2506 HLPLKP 2511
LP KP
Sbjct: 592 LLPPKP 597
Score = 35.0 bits (79), Expect = 1.4
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLP 3225
Q++ ++ P QPP PP PPP PQLP
Sbjct: 545 QEEGEKVLPPQPQPPLPPPPPPPPPPQLP 573
Score = 35.0 bits (79), Expect = 1.4
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 453 SEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELD--EELEDRPHEE 510
+E ++ EEEE EEE EE+ EE+ + +EEE E K P + E P +
Sbjct: 946 AEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQA 1005
Query: 511 PGAAAGS 517
G +GS
Sbjct: 1006 LGQPSGS 1012
Score = 35.0 bits (79), Expect = 1.4
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 450 DCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSE 498
DC + + E EE EEE+ EE+ + +EEE E + E L P+E
Sbjct: 951 DCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTE 999
Score = 33.9 bits (76), Expect = 3.1
Identities = 33/166 (19%), Positives = 64/166 (38%), Gaps = 24/166 (14%)
Query: 1490 EEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTV 1549
E ++EEE D E+ + T + V + P L +GP ++ PS + C +
Sbjct: 960 ELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGP--PLQALGQPSGSFICEM 1017
Query: 1550 --CKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEP-----------------TSS 1590
C F+ + L H +++ +A +G+ +P T+S
Sbjct: 1018 PNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTS 1077
Query: 1591 PDNKP---FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAAS 1633
+ P F C C + + + HM++ Q + + K + A+
Sbjct: 1078 GETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAA 1123
Score = 33.1 bits (74), Expect = 5.3
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 24/88 (27%)
Query: 3383 LQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKES----------------PKPEEQKN 3426
L+Q++ +KV QP+ P PP P P P ES PKP Q
Sbjct: 543 LKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGF 602
Query: 3427 TPREVSPLLPKLPEEPEAESKSADSLYD 3454
T V+ P A K A S+ D
Sbjct: 603 TNSTVA--------APSARDKPASSMSD 622
Score = 32.7 bits (73), Expect = 6.9
Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 21/125 (16%)
Query: 3112 PTAYPALQGIPPVLLPGLNSPSLPGFTPS------NTALTSPKPNLMGLPSTTVPSPGLP 3165
P P L PP P P TP L PKP+ G ++TV +P
Sbjct: 554 PQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSAR 613
Query: 3166 TSGLPNKPSSASLSSPTPA---------QATMAMGPQQPPQQQQQ-QQQPQVQQPPPPPA 3215
+KP+S+ P A P + Q++++ + +P+ PPPP+
Sbjct: 614 -----DKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPS 668
Query: 3216 AQPPP 3220
P P
Sbjct: 669 YNPNP 673
Score = 32.3 bits (72), Expect = 9.0
Identities = 17/42 (40%), Positives = 23/42 (54%)
Query: 445 EVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEE 486
E+ D SE+ E EEE EE+ EE+ +EEE E + E
Sbjct: 947 EIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPE 988
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 82.4 bits (202), Expect = 8e-15
Identities = 149/688 (21%), Positives = 249/688 (36%), Gaps = 154/688 (22%)
Query: 1572 KLKRALQESATGQPEPTSSPDNKPF-KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLE 1630
+++ A++++ + + ++ F K T + S + L IH R + H K++A+ +
Sbjct: 22 QIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDI-HNKKSQASVSD 80
Query: 1631 AASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGM 1690
+ + TG ++ + P G S + +L Q P + GM
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPP----RGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM 136
Query: 1691 PPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQA 1750
P + + A+P + + L +Q QQQQQ QQQQQQQQQ Q AQ Q+
Sbjct: 137 APHSMAV-VSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ-QS 194
Query: 1751 QVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLN 1810
+Q Q +QQQ L Q Q QQQQHL+ + + Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQ--------------------QQQQHLIKLHHQNQQQIQQQ 234
Query: 1811 PEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQP 1870
+ + AQ+Q+ QQ QQ QQQQ Q Q+ + QP
Sbjct: 235 QQQLQRI-------------------AQLQLQQQQQQQ--QQQQQQQQQALQAQPPIQQP 273
Query: 1871 S-QHPEKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEP 1929
Q P+ + ++ ++ + + + + P ++P
Sbjct: 274 PMQQPQPPPSQALPQQLQQMHHTQHH------------------QPPPQPQQPPVAQNQP 315
Query: 1930 SMLPPRIASDARGNATKAL----------LENFGFELVIQYNENKQKVQKKNGKTDQGEN 1979
S LPP+ + + +AL L+ +V+Q + +VQ++ +
Sbjct: 316 SQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
Query: 1980 LEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEP 2039
+ + + V Q+ P +Q QTP+
Sbjct: 376 AQMV----------------APGVQVSQSSLPMLSSPSPGQQV------------QTPQS 407
Query: 2040 PPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSP 2099
PPPP P P P QP+S P S+ P SP+ + L P P SP
Sbjct: 408 MPPPPQPSPQP-----GQPSSQPNSNVSSGPAPSPS----------SFLPSPSPQPSQSP 452
Query: 2100 LMMQTMPLQTLPAQLPPQLGPVEPL----PADLAQLYQHQLNPTLLQQQNKRPRTRITDD 2155
+ +T ++P+ P PV P PA +Q + Q D
Sbjct: 453 VTARTPQNFSVPSPGPLNT-PVNPSSVMSPAGSSQAEEQQYL-----------------D 494
Query: 2156 QLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPP 2215
+L+ L +Y + P I ++ + + K ++ L +K P
Sbjct: 495 KLKQLSKYIE----PLRRMINKIDKNEDRKKDLSK--MKSLLDILTDPSKRCPLKTLQKC 548
Query: 2216 ITSLEELKIDSRPPSPEPP-----KQEY 2238
+LE+LK D P+P PP KQ+Y
Sbjct: 549 EIALEKLKNDMAVPTPPPPPVPPTKQQY 576
Score = 57.8 bits (138), Expect = 2e-07
Identities = 76/316 (24%), Positives = 117/316 (37%), Gaps = 36/316 (11%)
Query: 3184 AQATMAMGPQQPPQQQQQQQQPQVQQPP----PPPAAQPPPTPQLPLQQQQQRKDKDSEK 3239
AQ + QQ QQQQQQQQ QPP P QPPP+ LP Q QQ + +
Sbjct: 242 AQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP 301
Query: 3240 VKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPL----PTMEYAVDPAQLQ--ALQA 3293
+ ++ + +P +P + + + + A + + P +++ P +Q +Q
Sbjct: 302 PPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQP 361
Query: 3294 ALTSDPTALLTSQFLPYFVPGFS------PYYAPQIPG-ALQSGYLQPMYGMEGLFPYSP 3346
+ TA+ T+Q PG P + PG +Q+ P P P
Sbjct: 362 QVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQP 421
Query: 3347 ALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG 3406
+ SQ +S G L Q Q + + Q P TPV
Sbjct: 422 S-SQPNSNVSSGPA----PSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPV--- 473
Query: 3407 APSPDKDPAKESPKPEEQ-----KNTPREVSPLLPKLPEEPEAESKSAD-----SLYDPF 3456
PS PA S E+Q K + + PL + + + E + D SL D
Sbjct: 474 NPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDIL 533
Query: 3457 IVPKVQYKL-VCRKCQ 3471
P + L +KC+
Sbjct: 534 TDPSKRCPLKTLQKCE 549
Score = 57.0 bits (136), Expect = 3e-07
Identities = 90/367 (24%), Positives = 135/367 (36%), Gaps = 47/367 (12%)
Query: 3105 PLQALNLPTAYPALQ----GIPP----VLLPGLNS-------PSLPGFTPSNTALTSPKP 3149
P+ AL T PA G+PP L G+ S SL G P T+ P
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTS--GMAP 138
Query: 3150 NLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQ 3209
+ M + ST P L + + QA + Q QQQQQQQQ Q QQ
Sbjct: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-----QQQQQQQQQQQFQAQQ 193
Query: 3210 PPPPPAAQPPPTPQLPLQQQQQRKD-------KDSEKVKEKEKAHKGKGE-PLPVPKKEK 3261
Q Q LQQQQQ++ ++ ++++++++ + + L ++++
Sbjct: 194 SAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
Query: 3262 GEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAP 3321
+ + A P + + Q QA P L + P P P
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQAL----PQQLQQMHHTQHHQPPPQPQQPP 309
Query: 3322 QIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQR 3381
Q L P + L + AL PG +L Y Q A QQ
Sbjct: 310 VAQN--QPSQLPPQSQTQPLVSQAQAL--------PGQML--YTQPPLKFVRAPMVVQQP 357
Query: 3382 QLQQQ-QQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPE 3440
+Q Q QQQ+ Q +A+Q P S P SP P +Q TP+ + P P+
Sbjct: 358 PVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417
Query: 3441 EPEAESK 3447
+ S+
Sbjct: 418 PGQPSSQ 424
Score = 56.2 bits (134), Expect = 6e-07
Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPV-PPGAPSPDKDPAKESPK 3420
QQ QQ QQ LQ Q Q Q+Q QQQQQQ+ QQQQ +Q P+ P P P++ P+
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288
Query: 3421 PEEQKNTPREVSPLLPKLPEEPEAESKSADSL 3452
+Q + + P P P++P L
Sbjct: 289 QLQQMHHTQHHQP--PPQPQQPPVAQNQPSQL 318
Score = 47.0 bits (110), Expect = 4e-04
Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query: 2439 QPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSS 2498
Q Q Q++Q Q +LQ Q+Q +Q+ QQ+ L + P + QPP Q P P P S
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQP----PPSQ 284
Query: 2499 PSPSQLSHLPLKPLHTSTPQ---------QLANLPPQ 2526
P QL + H PQ Q + LPPQ
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
Score = 43.5 bits (101), Expect = 0.004
Identities = 40/161 (24%), Positives = 60/161 (37%), Gaps = 33/161 (20%)
Query: 2430 PKLAEAPSAQPNQTQEKQG----------QPKPELQQQEQPEQKTNTPQQKLPQLVSLPS 2479
P + + P QP Q++ P ++ Q P + +P Q++ S+P
Sbjct: 351 PMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPP 410
Query: 2480 LPQPPPQ----------------APPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANL 2523
PQP PQ AP P LP SP PSQ P+ TPQ +
Sbjct: 411 PPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ------SPVTARTPQNFSVP 464
Query: 2524 PPQLIPYQCDQCKLAFPSFEHWQEHQQ-LHFLSAQNQFIHP 2563
P + + + P+ E QQ L L +++I P
Sbjct: 465 SPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEP 505
Score = 42.0 bits (97), Expect = 0.011
Identities = 59/278 (21%), Positives = 95/278 (34%), Gaps = 47/278 (16%)
Query: 3046 QQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTP 3105
QQH+ K+ Q+ ++++ + QL QQ+ + ++ + A Q Q P
Sbjct: 217 QQHLIKLHHQNQQQIQQQQQQLQ--RIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP 274
Query: 3106 LQALNLPTAYPALQGIPPVLLPGLNSP-SLPGFTPSNTALTSPKPNLMGLPSTTVP---- 3160
+Q P + Q +P L ++ P P + +P+ + S T P
Sbjct: 275 MQQPQPPPS----QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQ 330
Query: 3161 SPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQ---------------- 3204
+ LP L +P + +P M QQPP Q Q QQQ
Sbjct: 331 AQALPGQMLYTQPPLKFVRAP--------MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPG 382
Query: 3205 --------PQVQQPPPPPAAQPP---PTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEP 3253
P + P P Q P P P P Q Q + + V P
Sbjct: 383 VQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLP 442
Query: 3254 LPVPKKEKGEAPTATAATISAPLP-TMEYAVDPAQLQA 3290
P P+ + T S P P + V+P+ + +
Sbjct: 443 SPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 480
Score = 42.0 bits (97), Expect = 0.011
Identities = 51/235 (21%), Positives = 81/235 (34%), Gaps = 21/235 (8%)
Query: 2431 KLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSL---------P 2481
++A+ Q Q Q++Q Q + + Q + P Q+ Q + P +LP
Sbjct: 240 RIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH 299
Query: 2482 QPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPS 2541
QPPPQ P Q S P Q PL + P Q+ P L + P
Sbjct: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV 359
Query: 2542 FEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSA 2601
Q+ Q + Q + P +P + S+P Q+ + P +
Sbjct: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPML----SSPSPGQQVQTPQSMPPPPQPS 415
Query: 2602 TSPSTPTSTMNTLKRKLEEKASASPGENDSG-TGGEEPQRDKRLRTTITPEQLEI 2655
P P+S N+ S+ P + S PQ + T TP+ +
Sbjct: 416 PQPGQPSSQPNS-------NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSV 463
Score = 41.2 bits (95), Expect = 0.019
Identities = 41/157 (26%), Positives = 60/157 (38%), Gaps = 11/157 (7%)
Query: 3093 LAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKPNLM 3152
+ QQ + Q + TA A P V + + P L +P T P M
Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQT---PQSM 408
Query: 3153 GLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQ-QPPQQQQQQQQPQ-VQQP 3210
P P PG P+S +P+S S P P+ ++ P QP Q + PQ P
Sbjct: 409 PPPPQPSPQPGQPSS----QPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVP 464
Query: 3211 PPPPAAQP--PPTPQLPLQQQQQRKDKDSEKVKEKEK 3245
P P P P + P Q + + +K+K+ K
Sbjct: 465 SPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSK 501
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 79.7 bits (195), Expect = 5e-14
Identities = 153/712 (21%), Positives = 257/712 (36%), Gaps = 162/712 (22%)
Query: 1572 KLKRALQESATGQPEPTSSPDNKPF-KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLE 1630
+++ A++++ + + ++ F K T + S + L IH R + H K++A+ +
Sbjct: 22 QIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDI-HNKKSQASVSD 80
Query: 1631 AASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGM 1690
+ + TG ++ + P G S + +L Q P + GM
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPP----RGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM 136
Query: 1691 PPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQA 1750
P + + A+P + + L +Q QQQQQ QQQQQQQQQ Q AQ Q+
Sbjct: 137 APHSMAV-VSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ-QS 194
Query: 1751 QVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLN 1810
+Q Q +QQQ L Q Q QQQQHL+ + + Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQ--------------------QQQQHLIKLHHQNQQQIQQQ 234
Query: 1811 PEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQP 1870
+ + AQ+Q+ QQ QQ QQQQ Q Q+ + QP
Sbjct: 235 QQQLQRI-------------------AQLQLQQQQQQQ--QQQQQQQQQALQAQPPIQQP 273
Query: 1871 S-QHPEKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEP 1929
Q P+ + ++ ++ + + + + P ++P
Sbjct: 274 PMQQPQPPPSQALPQQLQQMHHTQHH------------------QPPPQPQQPPVAQNQP 315
Query: 1930 SMLPPRIASDARGNATKAL----------LENFGFELVIQYNENKQKVQKKNGKTDQGEN 1979
S LPP+ + + +AL L+ +V+Q + +VQ++ +
Sbjct: 316 SQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
Query: 1980 LEKL--------ECDSCGKLF----------------SNILILKSHQEHVHQNYFPFKQL 2015
+ + E + G + S+I + + V Q+ P
Sbjct: 376 AQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSS 435
Query: 2016 ERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPT 2075
+Q QTP+ PPPP P P P QP+S P S+ P SP+
Sbjct: 436 PSPGQQV------------QTPQSMPPPPQPSPQP-----GQPSSQPNSNVSSGPAPSPS 478
Query: 2076 IAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPL----PADLAQL 2131
+ L P P SP+ +T ++P+ P PV P PA +Q
Sbjct: 479 ----------SFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNT-PVNPSSVMSPAGSSQA 527
Query: 2132 YQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKH 2191
+ Q D+L+ L +Y + P I ++ + + K
Sbjct: 528 EEQQYL-----------------DKLKQLSKYIE----PLRRMINKIDKNEDRKKDLSK- 565
Query: 2192 WFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPP-----KQEY 2238
++ L +K P +LE+LK D P+P PP KQ+Y
Sbjct: 566 -MKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQY 616
Score = 65.1 bits (157), Expect = 1e-09
Identities = 71/300 (23%), Positives = 111/300 (37%), Gaps = 39/300 (13%)
Query: 3184 AQATMAMGPQQPPQQQQQQQQPQVQQPP----PPPAAQPPPTPQLPLQQQQQRKDKDSEK 3239
AQ + QQ QQQQQQQQ QPP P QPPP+ LP Q QQ + +
Sbjct: 242 AQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP 301
Query: 3240 VKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPL----PTMEYAVDPAQLQ--ALQA 3293
+ ++ + +P +P + + + + A + + P +++ P +Q +Q
Sbjct: 302 PPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQP 361
Query: 3294 ALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALM 3353
+ TA+ T+Q PG I AL G + + FP + A+S
Sbjct: 362 QVQQQQTAVQTAQAAQMVAPG-----VQMITEALAQGGMH----IRARFPPTTAVSAIPS 412
Query: 3354 GLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQ------QQKVQQQQPKASQTPVPPGA 3407
P Q Q SL +Q+Q Q Q Q QP +
Sbjct: 413 SSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472
Query: 3408 PSPDKDPAKESPKPEEQKN-----TPREVS---------PLLPKLPEEPEAESKSADSLY 3453
P+P SP P+ ++ TP+ S P+ P P S++ + Y
Sbjct: 473 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY 532
Score = 56.2 bits (134), Expect = 6e-07
Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPV-PPGAPSPDKDPAKESPK 3420
QQ QQ QQ LQ Q Q Q+Q QQQQQQ+ QQQQ +Q P+ P P P++ P+
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288
Query: 3421 PEEQKNTPREVSPLLPKLPEEPEAESKSADSL 3452
+Q + + P P P++P L
Sbjct: 289 QLQQMHHTQHHQP--PPQPQQPPVAQNQPSQL 318
Score = 47.0 bits (110), Expect = 4e-04
Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query: 2439 QPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSS 2498
Q Q Q++Q Q +LQ Q+Q +Q+ QQ+ L + P + QPP Q P P P S
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQP----PPSQ 284
Query: 2499 PSPSQLSHLPLKPLHTSTPQ---------QLANLPPQ 2526
P QL + H PQ Q + LPPQ
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
Score = 45.4 bits (106), Expect = 0.001
Identities = 33/75 (44%), Positives = 42/75 (56%), Gaps = 9/75 (12%)
Query: 3333 QPMYGMEGLFPYSPAL-----SQALMGLSPGSLLQQYQQ--YQQSLQEAIQQQQQRQLQQ 3385
QP G G+ P+S A+ Q + L +L QQ QQ +QQ Q A+QQQQQ+Q QQ
Sbjct: 128 QPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQ 187
Query: 3386 --QQQQKVQQQQPKA 3398
Q QQ QQQ +A
Sbjct: 188 QFQAQQSAMQQQFQA 202
Score = 45.4 bits (106), Expect = 0.001
Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 23/146 (15%)
Query: 2435 APSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQ-------- 2486
A SA P+ + QP ++ Q P + +P Q++ S+P PQP PQ
Sbjct: 406 AVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQP 465
Query: 2487 --------APPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLA 2538
AP P LP SP PSQ P+ TPQ + P + + +
Sbjct: 466 NSNVSSGPAPSPSSFLPSPSPQPSQ------SPVTARTPQNFSVPSPGPLNTPVNPSSVM 519
Query: 2539 FPSFEHWQEHQQ-LHFLSAQNQFIHP 2563
P+ E QQ L L +++I P
Sbjct: 520 SPAGSSQAEEQQYLDKLKQLSKYIEP 545
Score = 42.4 bits (98), Expect = 0.009
Identities = 79/324 (24%), Positives = 118/324 (36%), Gaps = 47/324 (14%)
Query: 3105 PLQALNLPTAYPALQ----GIPP----VLLPGLNS-------PSLPGFTPSNTALTSPKP 3149
P+ AL T PA G+PP L G+ S SL G P T+ P
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTS--GMAP 138
Query: 3150 NLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQ 3209
+ M + ST P L + + QA + Q QQQQQQQQ Q QQ
Sbjct: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-----QQQQQQQQQQQFQAQQ 193
Query: 3210 PPPPPAAQPPPTPQLPLQQQQQRKD-------KDSEKVKEKEKAHKGKGE-PLPVPKKEK 3261
Q Q LQQQQQ++ ++ ++++++++ + + L ++++
Sbjct: 194 SAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
Query: 3262 GEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAP 3321
+ + A P + + Q QA P L + P P P
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQAL----PQQLQQMHHTQHHQPPPQPQQPP 309
Query: 3322 QIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQR 3381
Q L P + L + AL PG +L Y Q A QQ
Sbjct: 310 VAQN--QPSQLPPQSQTQPLVSQAQAL--------PGQML--YTQPPLKFVRAPMVVQQP 357
Query: 3382 QLQQQ-QQQKVQQQQPKASQTPVP 3404
+Q Q QQQ+ Q +A+Q P
Sbjct: 358 PVQPQVQQQQTAVQTAQAAQMVAP 381
Score = 40.4 bits (93), Expect = 0.033
Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 18/186 (9%)
Query: 3074 QLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYP---ALQGIPPVLLPGLN 3130
Q QQ+ ++ A +A Q + + +++ +P A+ IP +P
Sbjct: 360 QPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGR 419
Query: 3131 SPSLPGFTPSNTALTSPKPNL-------MGLPSTTVPSPGLPTSGLPNKPSSASLSSPTP 3183
P S L+SP P M P P PG P+S +P+S S P P
Sbjct: 420 QPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS----QPNSNVSSGPAP 475
Query: 3184 AQATMAMGPQ-QPPQQQQQQQQPQ-VQQPPPPPAAQP--PPTPQLPLQQQQQRKDKDSEK 3239
+ ++ P QP Q + PQ P P P P P + P Q + + +K
Sbjct: 476 SPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDK 535
Query: 3240 VKEKEK 3245
+K+ K
Sbjct: 536 LKQLSK 541
Score = 38.9 bits (89), Expect = 0.096
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 18/112 (16%)
Query: 2431 KLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSL---------P 2481
++A+ Q Q Q++Q Q + + Q + P Q+ Q + P +LP
Sbjct: 240 RIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH 299
Query: 2482 QPPPQAPPPQC---------PLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
QPPPQ P P Q+ P SQ LP + L+T P + P
Sbjct: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAP 351
Score = 33.1 bits (74), Expect = 5.3
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 9/94 (9%)
Query: 2430 PKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPP 2489
P L+ Q QT + P Q QP + N+ P LP P PQ P
Sbjct: 431 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ--P 488
Query: 2490 PQCPL----PQ--SSPSPSQLSHLPLKPLHTSTP 2517
Q P+ PQ S PSP L + P+ P +P
Sbjct: 489 SQSPVTARTPQNFSVPSPGPL-NTPVNPSSVMSP 521
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 71.2 bits (173), Expect = 2e-11
Identities = 135/486 (27%), Positives = 178/486 (36%), Gaps = 110/486 (22%)
Query: 1722 RQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFP 1781
+QQQQQQQ QQQQQQQ QQQ Q L Q Q Q Q QQ+ QQQ Q L N +
Sbjct: 3932 QQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQ----QMGLLNQS------ 3981
Query: 1782 MTTETLLQLQQQQHLLFP---------FYIPSA-----------EFQLNPEVSLPVTSGA 1821
T + Q QQQQ L P F P A + ++P VS T G
Sbjct: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041
Query: 1822 LT------LTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPE 1875
T GT P + +V+ Q+L Q Q Q Q S LQP
Sbjct: 4042 STHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQ---PQPSSLQLQP----- 4093
Query: 1876 KKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEPSMLPPR 1935
L + ++++ +A GG +L G SE S +P
Sbjct: 4094 ---PLRLPGQQQQQVSLLHTAGGGSHG-----------------QLGSGSSSEASSVPHL 4133
Query: 1936 IA------SDARGNATKALL--ENFGFELVIQYNENKQK------VQKKNGKTDQG--EN 1979
+A D G+ T+ LL + E +Q N Q +Q G G
Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193
Query: 1980 LEKLECDSCGKLFSN--ILILKSHQEHVHQNYFPFKQLE-----RFAKQYRDHYDKLYPL 2032
+ +L G L N + L Q+ Q +QL+ R Y++ + PL
Sbjct: 4194 VGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPL 4253
Query: 2033 ------RPQTPEPPPP-----------PPPPPPPPLPAAPPQPASTPAIPASAPPITSPT 2075
+PQ P P P P PP LPA P ++ P + P T P
Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP--TPPP 4311
Query: 2076 IAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLP--AQLPPQLGPVEPLPADLAQ-LY 2132
+P +P P S +LP + L T P P L P G V P A LA L+
Sbjct: 4312 SSPQEPKRPSQLPSPSSQLPTEAQL-PPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLF 4370
Query: 2133 QHQLNP 2138
L P
Sbjct: 4371 SKGLGP 4376
Score = 60.5 bits (145), Expect = 3e-08
Identities = 84/341 (24%), Positives = 132/341 (38%), Gaps = 66/341 (19%)
Query: 3123 PVLLPGLNSPSLPGFTPSNTALTSPKPNLMGL--PSTTVPSPGLPTSGLPNKPSSASLSS 3180
P+L P SP P P + TSP P L P +P+ LP + ++P S S
Sbjct: 439 PLLPPPEESPLSP---PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS 495
Query: 3181 PTPAQATMAMGPQQPP--QQQQQQQQPQVQQPP---------PPPAAQP--PPTPQLPLQ 3227
P P ++ ++ P+ P ++ P + PP PPP A P PP + PL
Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555
Query: 3228 QQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQ 3287
+ S + + + P+ P +E +P A+ + P + P
Sbjct: 556 PPPEEL-PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE- 613
Query: 3288 LQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPA 3347
++ L+ P A S+ P P +P P +S P P
Sbjct: 614 ----ESPLSPPPEA---SRLSP------PPEDSPMSPPPEESPMSPP-----------PE 649
Query: 3348 LSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVP--- 3404
+S+ LSP ++ + ++ L ++ P+AS+ P
Sbjct: 650 VSR----LSPLPVVSRLS----------PPPEESPLSPPPEESPTSPPPEASRLSPPPED 695
Query: 3405 -PGAPSPDKDPAKESPKPEEQ-KNTPREVSPLLPKLPEEPE 3443
P +P P+ PA SP PE+ + P E SPLLP LPEEP+
Sbjct: 696 SPTSPPPEDSPA--SPPPEDSLMSLPLEESPLLP-LPEEPQ 733
Score = 59.7 bits (143), Expect = 5e-08
Identities = 73/250 (29%), Positives = 100/250 (40%), Gaps = 52/250 (20%)
Query: 1694 GNPIGANIASPSEPKEANRKKL-ADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQV 1752
G+ G + S + + KL A + S QQ QQQQQ QQQQQ QQQQ Q L Q Q
Sbjct: 3868 GSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQ 3927
Query: 1753 QAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPE 1812
Q LQQ+ QQQ Q Q + L Q QQQQ +FQ +
Sbjct: 3928 QQQLQQQQQQQQLQQQQQ-------QQLQQQQQQLQQQQQQQ---------QQQFQQQQQ 3971
Query: 1813 VSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ 1872
+ Q+ + QS + PQQQQ Q +A +P Q
Sbjct: 3972 -----------------------QQQMGLLNQSRTLLSPQQQQQQ-QVALGPGMPAKPLQ 4007
Query: 1873 HPEKKN----KLVIKEKEKESQRERDSAEGGEGNT----GPKE--TLPDALKAKEKKELA 1922
H L++ KE+ + S+E EG + GP T P+++ A E E+
Sbjct: 4008 HFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM-ATEPGEVK 4066
Query: 1923 PGGGSEPSML 1932
P + +L
Sbjct: 4067 PSLSGDSQLL 4076
Score = 55.5 bits (132), Expect = 1e-06
Identities = 103/409 (25%), Positives = 152/409 (37%), Gaps = 70/409 (17%)
Query: 3061 DKEKEYFDPATVRQLMAQQELDRIKKAN-EVLGLAA------------QQQGMFDNTPLQ 3107
+ + E T +Q Q++LD+++K E L A QQQ ++ +
Sbjct: 3558 EADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVL 3617
Query: 3108 ALNLPTAYPALQGIPPVLLPG--LNSPS-LPGFTPSNTALTSPKPNLMGLPSTTVPSPGL 3164
AL+ + L +P LLPG L P PG LT L G P + L
Sbjct: 3618 ALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTAL 3677
Query: 3165 PTSGLPNKPSSA-SLSSPTPA-----QATMAMGP--------QQPPQQQQQQQQPQVQQP 3210
A SL+ P+ A ++GP Q QQQ+ Q ++QQ
Sbjct: 3678 AQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQ 3737
Query: 3211 PPPPAAQPPPTPQLPLQQQQQRKD--KDSEKVKEKEK------AHKG----KGEPLPVPK 3258
Q Q+ +QQQQQ+ + ++ + K + +H+G + P P P+
Sbjct: 3738 QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP-PQ 3796
Query: 3259 KEKGEAPTATAATISAPLPTMEYAVDP-AQLQALQAALTSDPTA-----------LLTSQ 3306
+G A A + P P Q+ Q+ + S P L+T+Q
Sbjct: 3797 GPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQ 3856
Query: 3307 F---------------LPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQA 3351
L + + A G LQ + + L Q
Sbjct: 3857 QQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQ 3916
Query: 3352 LMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQ 3400
L LQQ Q QQ Q+ +QQQQQ+QLQQQQQQ QQQQ + Q
Sbjct: 3917 QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQ 3965
Score = 52.0 bits (123), Expect = 1e-05
Identities = 82/357 (22%), Positives = 128/357 (35%), Gaps = 41/357 (11%)
Query: 3122 PPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSP 3181
PP P P F+P + SP P + PSP L T P P AS SP
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSP-------PEESPPSPALETPLSP--PPEASPLSP 547
Query: 3182 TPAQATMAMGPQQ----PPQQQQQQQQPQVQQP--PPP---PAAQPPPTPQL--PLQQQQ 3230
++ ++ P++ PP + + P + P PPP P + PP +L P ++
Sbjct: 548 PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP 607
Query: 3231 QRKDKDSEKVKEKEKAHK----GKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPA 3286
+ + +A + + P+ P +E +P + +S PLP + P
Sbjct: 608 LSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS-PLPVVSRLSPPP 666
Query: 3287 QLQALQAALTSDPTALLTSQFLPYFVPGFSPYY-----APQIPGALQSGYLQPMYGMEGL 3341
+ L PT+ P SP +P P S P+ L
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726
Query: 3342 -FPYSPALSQALMG--LSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKA 3398
P P L G LSP + + L ++ ++ Q ++P
Sbjct: 727 PLPEEPQLCPRSEGPHLSP-------RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL 779
Query: 3399 SQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDP 3455
P P SP + SP+PEE +P+ P L +PEEP + +S P
Sbjct: 780 CAVPEEPHL-SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Score = 50.1 bits (118), Expect = 4e-05
Identities = 43/156 (27%), Positives = 68/156 (43%), Gaps = 17/156 (10%)
Query: 2370 DAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEK 2429
+ M +L P S +P P ++ ++P P A+ +L+ EEL + EA
Sbjct: 436 EEMPLLPPPEESPLSPPPEESPTSPPPEAS--------RLSPPPEELPA-SPLPEALHLS 486
Query: 2430 PKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPP 2489
L E+P + P +E P PE E+ +P ++ P +L + PPP+A P
Sbjct: 487 RPLEESPLSPP--PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544
Query: 2490 PQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPP 2525
P +S SP P + L TS P + + L P
Sbjct: 545 LSPPFEESPLSP------PPEELPTSPPPEASRLSP 574
Score = 50.1 bits (118), Expect = 4e-05
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 36/132 (27%)
Query: 2031 PLRPQTPEPPPPPPP------PPPPPLPAAP--------------------------PQP 2058
PL P E P PPP PPP LPA+P P P
Sbjct: 448 PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPP 507
Query: 2059 ASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQ---TMPLQTLPAQLP 2115
S+P P P++ P +P P++ T LS P E SP + + P + LP P
Sbjct: 508 ESSPFSPLEESPLSPPEESPPSPALE-TPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566
Query: 2116 PQLGPVEPLPAD 2127
P+ + P P +
Sbjct: 567 PEASRLSPPPEE 578
Score = 50.1 bits (118), Expect = 4e-05
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 2032 LRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091
L P+ +PP P P PP P P P P P P SP + +P+ LS P
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL--GEPA-----LSEP 903
Query: 2092 MELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTL 2140
E P+ SPL + + L PQL P +PLP L+ + P L
Sbjct: 904 GEPPL-SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951
Score = 45.4 bits (106), Expect = 0.001
Identities = 97/393 (24%), Positives = 138/393 (35%), Gaps = 93/393 (23%)
Query: 3117 ALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSA 3176
AL+GI V+ G + PG +L + + L G PS+ + + SG + S+
Sbjct: 3431 ALKGIKKVMAQGSIGVA-PGMNRQQVSLLAQR--LSGGPSSDLQNHVAAGSG--QERSAG 3485
Query: 3177 SLSSPTPAQATMAMGPQQPPQQQQQQQ-----QPQVQQPPPPPAAQPPPTPQLPLQQQQQ 3231
S P P T A G Q+Q ++ Q +Q QL + ++Q
Sbjct: 3486 DPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQM-------------QLKVLEEQI 3532
Query: 3232 RKDKDSEKVK-EKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTM----------- 3279
+ S K K++ K G P EK + T + I L +
Sbjct: 3533 GVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLM 3592
Query: 3280 -EYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGY-LQPMYG 3337
EY Q Q Q +A+L P SP ++PG L G+ LQP G
Sbjct: 3593 AEYRNKQQQQQQQQQQQQQQHSAVLALS------PSQSPRLLTKLPGQLLPGHGLQPPQG 3646
Query: 3338 MEG-------------LFPYSP-------ALSQ-------------------------AL 3352
G P P AL+Q AL
Sbjct: 3647 PPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLAL 3706
Query: 3353 MGLSPGS-LLQQYQ-QYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
L P S LLQ+ Q Q QQ + Q+ QQ+Q QQQQQQ + Q Q PG +
Sbjct: 3707 RSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTN 3766
Query: 3411 D---KDPAKESPKPEEQKNTPREVSPLLPKLPE 3440
P P Q +++SP P+ P+
Sbjct: 3767 QALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQ 3799
Score = 45.4 bits (106), Expect = 0.001
Identities = 63/231 (27%), Positives = 96/231 (41%), Gaps = 15/231 (6%)
Query: 3167 SGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPL 3226
SG P K S+ + S Q + QQ QQQQQQQ Q QQ Q QL
Sbjct: 3884 SGQP-KLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQ 3942
Query: 3227 QQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVD-- 3284
QQQQQ + + + +++++ + + ++++ + T+ +P + V
Sbjct: 3943 QQQQQLQQQQQQLQQQQQQ----QQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALG 3998
Query: 3285 ---PAQ-LQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEG 3340
PA+ LQ + PT LLT + P S A + P Q G L E
Sbjct: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSS-EATEGPSTHQGGPLAIGTTPES 4057
Query: 3341 LFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKV 3391
+ + +L G S L+Q Q Q S ++Q Q +L QQQQ+V
Sbjct: 4058 MATEPGEVKPSLSGDSQLLLVQPQPQPQPS---SLQLQPPLRLPGQQQQQV 4105
Score = 45.1 bits (105), Expect = 0.001
Identities = 72/323 (22%), Positives = 112/323 (34%), Gaps = 45/323 (13%)
Query: 2370 DAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEK 2429
+A + P S +P P + ++P P A+ + + E + + EA
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 2430 PKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKT-------NTPQQKLPQLVSLPSLPQ 2482
P E+P + P +E P PE + P + + +P P++ L LP
Sbjct: 601 PPFEESPLSPP--PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
Query: 2483 PPPQAPPPQ----CPLPQSSPS--PSQLSHL--PLKPLHTSTPQQ-----------LANL 2523
+PPP+ P P+ SP+ P + S L P + TS P + L +L
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 2524 P------------PQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLD 2571
P PQL P P H + LS Q + H L +
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH---LSPQPE 775
Query: 2572 MPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDS 2631
P + P P L+ Q + P SP T ++ + E S P E+
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPE--EPCLSPQPEESHL 833
Query: 2632 GTGGEEPQRDKRLRTTITPEQLE 2654
EEP R + +LE
Sbjct: 834 SPQSEEPCLSPRPEESHLSPELE 856
Score = 45.1 bits (105), Expect = 0.001
Identities = 133/595 (22%), Positives = 195/595 (32%), Gaps = 114/595 (19%)
Query: 2875 LTKAAMMAMSEYEDRLSSGLVSPAPSFY---------------SKEYDNEGTVDYSETSS 2919
+ KA M+A+ + ++ G + AP S + N + S
Sbjct: 3424 IAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERS 3483
Query: 2920 LADPCSPSPGASGSA-GKSGDSGDRPGQK-RFRTQ-MTNLQLKVLKSCFNDYRTPTMLEC 2976
DP P P A G ++ R ++ F TQ + +QLKVL+ +R C
Sbjct: 3484 AGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALC 3543
Query: 2977 EVLGNDIGLPKRVVQVWFQNARAKEKKSKLSMAKHFGINQTSYEGPKTECTLCGIKYSAR 3036
AK++ +K + E P+ + +
Sbjct: 3544 ----------------------AKQRTAK----------KAGREFPEADAE------KLK 3565
Query: 3037 LSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQ 3096
L Q+ + +V+ + EY + +Q QQ+ + ++ + VL L+
Sbjct: 3566 LVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNK---QQQQQQQQQQQQQQHSAVLALSPS 3622
Query: 3097 QQGMF------DNTPLQALNLPTAYPALQGIPPVLLPG-LNSPSLPGFTPSNTALTSPKP 3149
Q P L P P Q L PG + P PG NTAL +
Sbjct: 3623 QSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQ 3682
Query: 3150 NLM--GLPSTTVPSPGLPTSGLPNK---PSSASLSSPTPAQATMAMGPQQPPQQQQQQQQ 3204
G S PS G L + P S L M Q QQQQQQQQ
Sbjct: 3683 QQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQ 3742
Query: 3205 PQ--------VQQP--------------PPPPAAQPPPTPQLPLQQQQQRKDKDSEK--- 3239
Q +QQ P P PP + Q L QQ + +
Sbjct: 3743 QQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGML 3802
Query: 3240 ----VKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTME-------YAVDPAQL 3288
V ++ H G P + + + +S+P + V Q
Sbjct: 3803 GPAQVAVLQQQHPGALGP----QGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ 3858
Query: 3289 QALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQS-GYLQPMYGMEGLFPYSPA 3347
Q Q A L+ P + Q G+LQ Q + + L
Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ 3918
Query: 3348 LSQALMGLSPGSLLQQYQQYQ--QSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQ 3400
Q L L QQ QQ Q Q Q+ +QQQQQ+ QQQQQQ+ Q QQ + Q
Sbjct: 3919 QLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQ 3973
Score = 44.7 bits (104), Expect = 0.002
Identities = 103/452 (22%), Positives = 150/452 (33%), Gaps = 104/452 (23%)
Query: 3105 PLQALNLPTAYPALQGIPPVLLP----GLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVP 3160
PL + A PAL + + P G + P P P SP P VP
Sbjct: 938 PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVP 997
Query: 3161 SPGLPTS-GLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPP 3219
LP S G P P+S L P P Q + + PQ Q P P+ P
Sbjct: 998 PMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP 1057
Query: 3220 PTPQLPLQQQQQRKDKDSEKVKEKE--KAHKGKGEPLPVPKKEKGEAPTATAATISAPLP 3277
+ + + + + ++EKV E E PLP P + +S P P
Sbjct: 1058 IGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGD-----------LSCPAP 1106
Query: 3278 TMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYG 3337
+ A+D + L D T+ PG P Q PG+L S
Sbjct: 1107 SPAPALDDF------SGLGED-----TAPLDGIDAPGSQP-EPGQTPGSLAS-------E 1147
Query: 3338 MEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPK 3397
++G SP L L+P + ++ Y + +Q+ + + +Q++P+
Sbjct: 1148 LKG----SPVLLDP-EELAPVTPMEVYPECKQTAGQGSPCE-------------EQEEPR 1189
Query: 3398 ASQTPVPP-------------------GAPSPDKDPAKESPKPEEQKNTPREVSPLLPKL 3438
A P PP A P +P SP PE + E+
Sbjct: 1190 APVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVS 1249
Query: 3439 PEEPEAESK-SADSLYDPFIVPKVQYKLVC----------RKCQAGFSDEEAARSHLK-- 3485
P E + DSL P+ L+C + + G ARS +K
Sbjct: 1250 PARDEGSLRLCTDSL------PETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQG 1303
Query: 3486 -SLCFFGQSVVNLQEMVLHVPTGGGGGGSGGG 3516
S F G+ P GG GG G G
Sbjct: 1304 RSSSFPGR----------RRPRGGAHGGRGRG 1325
Score = 44.7 bits (104), Expect = 0.002
Identities = 101/437 (23%), Positives = 151/437 (34%), Gaps = 66/437 (15%)
Query: 3046 QQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTP 3105
QQ + + + QL ++++ +Q QQ+ ++++ + QQQ
Sbjct: 3917 QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976
Query: 3106 LQALNLPTAYPALQGIPPVLL-PGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTV-PSPG 3163
L + P Q V L PG+ + L F S+ P L G TV P+
Sbjct: 3977 LLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHF--SSPGALGPTLLLTGKEQNTVDPAVS 4034
Query: 3164 LPTSGLPNKPSSASLS-SPTPAQATMAMGPQQPPQQQQQQQ---QPQVQQPPPPPAAQPP 3219
+ P+ L+ TP G +P Q QPQ Q P P + Q
Sbjct: 4035 SEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQ--PQPSSLQLQ 4092
Query: 3220 PTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTM 3279
P +LP QQQQQ V A G L G + A++ P++
Sbjct: 4093 PPLRLPGQQQQQ--------VSLLHTAGGGSHGQLG-----SGSSSEASSVPHLLAQPSV 4139
Query: 3280 EYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPG---ALQSGYLQPMY 3336
P + T L P PQ P LQSG Q +
Sbjct: 4140 SLGDQPGSM-----------TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSG--QGLP 4186
Query: 3337 GMEGLFPYSPALSQALMG-LSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQ 3395
G+ G+ P L L G L+ L+ QQ +A+ Q+Q Q Q +Q Q+
Sbjct: 4187 GV-GIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
Query: 3396 PKASQTPVP---------PGAPSPDKDPAKE---SPKPEEQKNTPR-----EVSPLL--- 3435
P +P+ G P P P +E P+P+ P P+L
Sbjct: 4246 PGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
Query: 3436 -----PKLPEEPEAESK 3447
P P+EP+ S+
Sbjct: 4306 HPTPPPSSPQEPKRPSQ 4322
Score = 43.5 bits (101), Expect = 0.004
Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 16/107 (14%)
Query: 2031 PLRPQTPEPPPP----PPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQP---SV 2083
PL P PP P P PPP P +PP S P S PP PT P + S
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEES----PLSPPPEELPTSPPPEASRLSP 574
Query: 2084 PLTQLSM---PMELPIFSPLMMQTM--PLQTLPAQLPPQLGPVEPLP 2125
P + M P E P+ P + P + P PP+ P+ P P
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
Score = 43.5 bits (101), Expect = 0.004
Identities = 58/239 (24%), Positives = 97/239 (40%), Gaps = 39/239 (16%)
Query: 1692 PLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQ 1751
P G N+A S ++ + + +Q+ Q Q+ QQQQQQQQQQ L Q
Sbjct: 3695 PSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVA-- 3752
Query: 1752 VQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQ--------QQHLLFPFYI- 1802
+QQ+ QQ + +Q P P ++ L +QQ Q +L P +
Sbjct: 3753 ----IQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVA 3808
Query: 1803 ------PSAEFQLNPEVSLPVTSGAL----TLTGTGPGLLED--LKAQVQVPQQSHQQI- 1849
P A P + +T + L G GL+ + AQ Q QQ HQQ
Sbjct: 3809 VLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQG 3868
Query: 1850 ----LPQQQQNQLS-------IAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAE 1897
L QQ+ +S AQ +L Q Q + + + +++++++ +++ +
Sbjct: 3869 SMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQ 3927
Score = 43.1 bits (100), Expect = 0.005
Identities = 66/275 (24%), Positives = 99/275 (36%), Gaps = 52/275 (18%)
Query: 2361 DDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFN 2420
++S +A + P S ++P P + ++P P + + L E L
Sbjct: 676 EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE------DSLMSLPLEESPLLPL- 728
Query: 2421 SKTEAGDEKPKL---AEAPSAQPNQTQEKQGQPKPELQQ-QEQPEQKTNTPQQKLPQLVS 2476
E+P+L +E P P + +E P+PE Q E+ +PQ + P L +
Sbjct: 729 ------PEEPQLCPRSEGPHLSP-RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCA 781
Query: 2477 LPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCK 2536
+P P PQA P SP P +L HL +PQ P L P + C
Sbjct: 782 VPEEPHLSPQAEGPHL-----SPQPEEL-HL--------SPQ---TEEPHLSPVPEEPCL 824
Query: 2537 LAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQI 2596
P H + LS + + H L L+ P + P P P+
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEESH---LSPELEKPPLSPRPEKP-----------PEE 870
Query: 2597 PASSATS---PSTPTSTMNTLKRKLEEKASASPGE 2628
P P P +L L E A + PGE
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
Score = 43.1 bits (100), Expect = 0.005
Identities = 51/164 (31%), Positives = 69/164 (42%), Gaps = 25/164 (15%)
Query: 1712 RKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQ------------VQAHLQQE 1759
+K+ +++A + +QQQQQQQQQQQQQQ A LA + +Q + H Q
Sbjct: 3585 QKEHTNLMAEYRNKQQQQQQQQQQQQQQHSA-VLALSPSQSPRLLTKLPGQLLPGHGLQP 3643
Query: 1760 LQ----QQAALIQSQLFNPTL--LPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEV 1813
Q QA ++ L P P L Q QQQQH A P
Sbjct: 3644 PQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQH------SGGAGSLAGPSG 3697
Query: 1814 SLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQ 1857
+ AL G LL++ + Q+Q + Q L QQQQ Q
Sbjct: 3698 GFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQ 3741
Score = 42.7 bits (99), Expect = 0.007
Identities = 88/370 (23%), Positives = 128/370 (34%), Gaps = 34/370 (9%)
Query: 3102 DNTPLQALNLPTAYP--ALQGIPPVLLPGLNSP--SLPGFTPSNTALTSPKP--NLMGLP 3155
++ P AL P + P A PP L+ P LP P + SP P + M P
Sbjct: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584
Query: 3156 STTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQ----QPPQQQQQQQQPQVQQP- 3210
P P + P S SP P ++ ++ P+ PP + P + P
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPM 644
Query: 3211 -PPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATA 3269
PPP ++ P P + + S +E + + L P ++ +P
Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPED 704
Query: 3270 ATISAP-------LPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPG-FSPYYAP 3321
+ S P LP E + P + Q S+ L P+ P P+ +P
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEP-QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763
Query: 3322 QIPGALQSGYLQPMYGMEGLFPYSPALSQALMG--LSPGS----LLQQYQQYQQSL--QE 3373
Q S QP P P LS G LSP L Q ++ S +E
Sbjct: 764 QAEEPHLSP--QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 3374 AIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPR-EVS 3432
Q + Q + P+ ++ + P P P E P PEE P E
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP-PEEPGQCPAPEEL 880
Query: 3433 PLLPKLPEEP 3442
PL P P EP
Sbjct: 881 PLFPP-PGEP 889
Score = 42.7 bits (99), Expect = 0.007
Identities = 36/114 (31%), Positives = 48/114 (42%), Gaps = 16/114 (14%)
Query: 2028 KLYPLRPQTPEPPPPPPPPPPPPLPAA---PP---QPASTP--AIPASAPPITS-----P 2074
+L P ++P PPP P PP A+ PP P S P P S PP S P
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP 630
Query: 2075 TIAPAQPSVPLTQLSMPMELPIFSPLMMQTM---PLQTLPAQLPPQLGPVEPLP 2125
+P P + +S P E+ SPL + + P + P PP+ P P P
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
Score = 42.4 bits (98), Expect = 0.009
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 10/104 (9%)
Query: 2028 KLYPLRPQTPEPPPP----PPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSV 2083
+L+P ++P PPP PPP + PP+ + P +P P ++ P
Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657
Query: 2084 PLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127
+++LS P E SP P + P PP+ + P P D
Sbjct: 658 VVSRLSPPPEESPLSP------PPEESPTSPPPEASRLSPPPED 695
Score = 42.4 bits (98), Expect = 0.009
Identities = 35/108 (32%), Positives = 45/108 (41%), Gaps = 13/108 (12%)
Query: 2040 PPPPPPPPPPPLPAAPPQPASTP----AIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095
PP P PPP P+ A PA +P P A + P A P + T +S P E
Sbjct: 931 PPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILE-TPISPPPEAN 989
Query: 2096 IFSPLMMQTMPLQTLPAQLPPQLGP-----VEPLPADLAQLYQHQLNP 2138
P + +P LP +GP +EPLP + L QH L P
Sbjct: 990 CTDP---EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP 1034
Score = 42.4 bits (98), Expect = 0.009
Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 13/105 (12%)
Query: 2026 YDKLYPLRPQTPEPPPPPPPP----PPPPLPAAP-------PQPASTPAIPASAPPITSP 2074
Y Y P TP P PPPP PP LP+ P PQ S+ P + P+++
Sbjct: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
Query: 2075 TIAPAQPSVPLTQLSMPMELPIFSPLMMQTM-PLQTLPAQLPPQL 2118
P+ P P Q P P P PL P PP++
Sbjct: 2434 AFCPS-PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEV 2477
Score = 42.0 bits (97), Expect = 0.011
Identities = 33/112 (29%), Positives = 41/112 (36%), Gaps = 21/112 (18%)
Query: 2029 LYPLRPQTPEPPPPPPPP--PPPPLPAAPPQPASTPA---------------IPASAPPI 2071
L P ++P PPP P PPP P P PA P S PP
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
Query: 2072 TSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEP 2123
SP ++P S P + L E P+ P P P PP+ P+ P
Sbjct: 500 ESP-LSPPPESSPFSPLE---ESPLSPPEESPPSPALETPLSPPPEASPLSP 547
Score = 42.0 bits (97), Expect = 0.011
Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 10/158 (6%)
Query: 2375 LTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAE 2434
L+P S +P S P ++ + L+ EEL T + EA P E
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT-SPPPEASRLSPPPEE 578
Query: 2435 APSAQPNQTQEKQGQPKPELQQQEQPEQKT-------NTPQQKLPQLVSLPSLPQPPPQA 2487
+P + P +E P PE + P +++ +P P+ L P+ P +
Sbjct: 579 SPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Query: 2488 PPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPP 2525
PPP+ P S+LS LP+ + P++ PP
Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Score = 42.0 bits (97), Expect = 0.011
Identities = 35/111 (31%), Positives = 45/111 (40%), Gaps = 22/111 (19%)
Query: 2031 PLRPQTPEPPPPPPP------PPPPPLPAAPPQPASTPAIPASA----PPITSPTIAPAQ 2080
PL P E P PPP PPP P +PP S + P A PP ++P
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612
Query: 2081 PSVPL------TQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLP 2125
PL ++LS P E SP P + P PP++ + PLP
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSP------PPEESPMSPPPEVSRLSPLP 657
Score = 42.0 bits (97), Expect = 0.011
Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 12/95 (12%)
Query: 2028 KLYPLRPQTPEPPPPPPPP--PPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPL 2085
+L P ++P PPP P PPP P P +P P PP SP P + S+
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP---PPEDSPASPPPEDSL-- 715
Query: 2086 TQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGP 2120
+S+P+E SPL+ Q P P L P
Sbjct: 716 --MSLPLE---ESPLLPLPEEPQLCPRSEGPHLSP 745
Score = 42.0 bits (97), Expect = 0.011
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 5/52 (9%)
Query: 2035 QTPEPPPPPPPPPPPPLPAAPPQPASTPAI-----PASAPPITSPTIAPAQP 2081
Q PPP P PPP PL +P P + P + P + PP+ SP + P
Sbjct: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP 4956
Score = 41.6 bits (96), Expect = 0.015
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSM 2090
PL + P PPP P PP P+ + T P ++ P PA P LS
Sbjct: 433 PLNEEMPLLPPPEESPLSPP-----PEESPTSPPPEASRLSPPPEELPASPLPEALHLSR 487
Query: 2091 PMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPL 2124
P+E SP P + P PP+ P PL
Sbjct: 488 PLEESPLSP------PPEESPLSPPPESSPFSPL 515
Score = 41.2 bits (95), Expect = 0.019
Identities = 34/102 (33%), Positives = 40/102 (39%), Gaps = 18/102 (17%)
Query: 2031 PLRPQTPEPPPPPPP---P--PPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPL 2085
PL P E P PPP P PPP P P +P P PP SP P + S
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP---PPEESPMSPPPEAS--- 597
Query: 2086 TQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127
+L P E SP P + P PP+ + P P D
Sbjct: 598 -RLFPPFEESPLSP------PPEESPLSPPPEASRLSPPPED 632
Score = 40.4 bits (93), Expect = 0.033
Identities = 57/246 (23%), Positives = 87/246 (35%), Gaps = 18/246 (7%)
Query: 3127 PGLNSPSLPGFTPSNTALTSPKP--NLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPA 3184
P +SP+ P P + SP P +LM LP P LP S SP P
Sbjct: 692 PPEDSPTSP---PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748
Query: 3185 QATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKV---K 3241
+ ++ P++P Q ++ QP P P P L Q + E++
Sbjct: 749 EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP 808
Query: 3242 EKEKAHKG--KGEPLPVPKKEKGEAPTATAATISAPLPTMEY---AVDPAQLQALQAALT 3296
+ E+ H EP P+ E+ + +P P + ++ L
Sbjct: 809 QTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP 868
Query: 3297 SDPTALLTSQFLPYFVPGFSPYYAPQI-PGALQSGYLQPMYGMEGLFPYS----PALSQA 3351
+P + LP F P P +P + AL P+ + P S P+LS
Sbjct: 869 EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQ 928
Query: 3352 LMGLSP 3357
LM P
Sbjct: 929 LMPPDP 934
Score = 40.4 bits (93), Expect = 0.033
Identities = 84/353 (23%), Positives = 119/353 (33%), Gaps = 52/353 (14%)
Query: 3095 AQQQGMFDNTPLQALNLPTAYPA----------LQGIPPVLLPGLNSPSLPGFTPSNTAL 3144
A + G +T L A P A PA G PP + SP F + + +
Sbjct: 2478 AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFV---RSPGTGAFVGTPSPM 2534
Query: 3145 TSPKPNLMGLPSTT--VPSPGLPTSGLPNKP--SSASLSSPTPAQATMAMGPQQPPQQQQ 3200
P +G PS VP PGLP N +L P T+A G P
Sbjct: 2535 RFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPL 2594
Query: 3201 QQQQPQVQQ-----PPPPPAAQPPPTP--QLP-LQQQQQRKDKDSEKVKEKEKAHKGKGE 3252
+ P PP+ PPP P LP L ++ + V+++E G G
Sbjct: 2595 GPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGS 2654
Query: 3253 PLPVPKKEKGEAP-----TATAATISAPLPTMEYAVDPAQLQ-----------ALQAALT 3296
L + + P + T + + Q+Q A A
Sbjct: 2655 SLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAV 2714
Query: 3297 SDPTALLTSQFLPYFVP---GFSPYYAPQ----IPGALQSGYLQPMYGMEGLFPYSPALS 3349
P + P F G +P+ Q + G S P+ G G FP LS
Sbjct: 2715 GPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILG-PGSFPSDDRLS 2773
Query: 3350 QALMGLSPGSLLQQYQQY---QQSLQEAIQQQQQRQLQQQQQQKVQQQQPKAS 3399
+ +P S+ +Q Q+ + LQQQQQQ QQQQ A+
Sbjct: 2774 RPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826
Score = 40.4 bits (93), Expect = 0.033
Identities = 100/449 (22%), Positives = 161/449 (35%), Gaps = 90/449 (20%)
Query: 1638 GTGNSSSISLSSSTPSPVSTSG--SNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLGN 1695
GTG SS ++ S +T G ++ T S S G S+LL + ES + G
Sbjct: 3169 GTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPG---GSSLLEKFELESGALTLPGG 3225
Query: 1696 PIGANIASPSEPKEANRKKLADMIAS----------RQQQQQQQQQQQQQQQQQQQAQTL 1745
P + +L +I ++QQ Q Q QQQQQQQQ +L
Sbjct: 3226 PAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSL 3285
Query: 1746 AQAQAQVQAHLQQELQQQAALI--QSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIP 1803
A QA +L Q QL P + L+ Q H L
Sbjct: 3286 LSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHAL------ 3339
Query: 1804 SAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQ---------- 1853
+ +L P +++ G + L+G G VPQQS Q +L Q+
Sbjct: 3340 --QQRLAPSMAMVSNQGHM-LSGQHGG------QAGLVPQQSSQPVLSQKPMGTMPPSMC 3390
Query: 1854 -QQNQLSIAQSHSALLQPSQHPEK-----------KNKLVIKEKEKE------------S 1889
+ QL++ Q + P +K K K+V + K+
Sbjct: 3391 MKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGM 3450
Query: 1890 QRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALL 1949
R++ S + GP L + + A +E + G S+P PP A A +
Sbjct: 3451 NRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQY 3510
Query: 1950 ENFGF------ELVIQYNENKQKVQKKNGK-------TDQGENLEKLECDSCGKLFSNIL 1996
E + F ++ ++ E + V +K+ K T + E E D+ +
Sbjct: 3511 EEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADA-----EKLK 3565
Query: 1997 ILKSHQEHVHQNYFPFKQLERFAKQYRDH 2025
++ Q + KQL++ KQ ++H
Sbjct: 3566 LVTEQQSKIQ------KQLDQVRKQQKEH 3588
Score = 40.4 bits (93), Expect = 0.033
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 7/55 (12%)
Query: 2034 PQTPEPPPPPPP-------PPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQP 2081
P EP PPP P PP PL P +P + P +P+ P +SP A +P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Score = 39.7 bits (91), Expect = 0.056
Identities = 48/160 (30%), Positives = 64/160 (40%), Gaps = 20/160 (12%)
Query: 3071 TVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGI---PPVLLP 3127
TV QL AQ + + K ++ L+ QQQ LQAL + Q + PP P
Sbjct: 4193 TVGQLRAQLQ-GVLAKNPQLRHLSPQQQQQ-----LQALLMQRQLQQSQAVRQTPPYQEP 4246
Query: 3128 GLNSPSLPGFTPSNTALTSPKPNLMGLPST-TVPSPGLPTSGLPNKPSSASLSSPTPAQA 3186
G + L G L +P L G P T P L P P L +P A +
Sbjct: 4247 GTQTSPLQG-------LLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPR--LPAPPGALS 4297
Query: 3187 T-MAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLP 3225
T +GP P Q+P+ P P++Q P QLP
Sbjct: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP 4337
Score = 39.3 bits (90), Expect = 0.073
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 14/95 (14%)
Query: 2029 LYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAI--PASAPPITSPTIAPAQPSVPLT 2086
L P + PE P P P PL P +P+ +P + PA + P P ++P +PL+
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP-GEPPLSPLPEELPLS 918
Query: 2087 QLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPV 2121
P P SP Q MP P LPP L P+
Sbjct: 919 ----PSGEPSLSP---QLMP----PDPLPPPLSPI 942
Score = 38.9 bits (89), Expect = 0.096
Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 14/109 (12%)
Query: 2037 PEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIA-----PAQPSVPLTQLSMP 2091
PEP PP PP P P P P +P P+ ++ P+Q S P LS+P
Sbjct: 993 PEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052
Query: 2092 MELPIFSPLM-------MQTMPLQTLPAQLPPQLGP--VEPLPADLAQL 2131
L ++ + M + + P L P PLP+ + L
Sbjct: 1053 SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDL 1101
Score = 38.5 bits (88), Expect = 0.13
Identities = 35/113 (30%), Positives = 48/113 (42%), Gaps = 13/113 (11%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSM 2090
PL + P P +P PP S P S PP SPT P + S +LS
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEES----PLSPPPEESPTSPPPEAS----RLSP 469
Query: 2091 PMELPIFSPL---MMQTMPLQTLPAQLPPQLGPVEPLP--ADLAQLYQHQLNP 2138
P E SPL + + PL+ P PP+ P+ P P + + L + L+P
Sbjct: 470 PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522
Score = 38.1 bits (87), Expect = 0.16
Identities = 67/327 (20%), Positives = 110/327 (33%), Gaps = 72/327 (22%)
Query: 3131 SPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAM 3190
SP PG TP++ +P+ + + P G TS P +P + +A + +
Sbjct: 373 SPPEPGDTPTD------EPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL 426
Query: 3191 GPQ-QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKG 3249
PQ + P ++ P ++ P P + PT P
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP------------------------ 462
Query: 3250 KGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLP 3309
+ L P +E +P A +S PL + P + + L+ P + S F P
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE-----SPLSPPPES---SPFSP 514
Query: 3310 YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQ 3369
SP AL++ P+ P SP ++ + P
Sbjct: 515 LEESPLSPPEESPPSPALET----PLSPPPEASPLSPPFEESPLSPPP------------ 558
Query: 3370 SLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPR 3429
+L + + P ++P+ +P P++ P SP PE + P
Sbjct: 559 -----------EELPTSPPPEASRLSPPPEESPM---SPPPEESPM--SPPPEASRLFPP 602
Query: 3430 -EVSPLLPKLPEEPEAESKSADSLYDP 3455
E SPL P E P + A L P
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPP 629
Score = 38.1 bits (87), Expect = 0.16
Identities = 38/159 (23%), Positives = 58/159 (36%), Gaps = 19/159 (11%)
Query: 2377 PTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAP 2436
P SS +P+ S P S + A L EA L+ E P E P
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP---PFEESPLSPPPEELP 562
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLV------SLPSLPQPPPQAPPP 2490
++ P + + P E PE+ +P + +L L P+ P +PPP
Sbjct: 563 TSPPPEA-SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
Query: 2491 QC----PLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPP 2525
+ P P+ SP P+ P P +++ L P
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPMSP-----PPEVSRLSP 655
Score = 37.7 bits (86), Expect = 0.21
Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 18/78 (23%)
Query: 2030 YPLRPQTPEPPPP-PPPPPPPPLPAAPP-----------QP----ASTPAIPASAPPITS 2073
YPL P+ P PP PP P P PA PP QP + P P P
Sbjct: 2183 YPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPD 2242
Query: 2074 PTIAPAQPSVPLTQLSMP 2091
P + P PS L L++P
Sbjct: 2243 PFLKPRCPS--LDNLAVP 2258
Score = 37.4 bits (85), Expect = 0.28
Identities = 51/217 (23%), Positives = 76/217 (35%), Gaps = 42/217 (19%)
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496
S QP + + G + +LQQQ+Q +Q+ QQ+ QL L Q Q Q L Q
Sbjct: 3884 SGQPKLSAQPMGSLQ-QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQ 3942
Query: 2497 SSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSA 2556
QQL QL Q Q + F+ Q+ QQ+ L+
Sbjct: 3943 QQQ------------------QQLQQQQQQLQQQQQQQQQ----QFQQQQQQQQMGLLNQ 3980
Query: 2557 QNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKR 2616
+ PQ + Q+ G P +PA S+P + TL
Sbjct: 3981 SRTLLSPQQQQQQ-----------------QVALG--PGMPAKPLQHFSSPGALGPTLLL 4021
Query: 2617 KLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQL 2653
+E+ + P + T G + L TPE +
Sbjct: 4022 TGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM 4058
Score = 37.4 bits (85), Expect = 0.28
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 21/81 (25%)
Query: 2042 PPPPPP-PPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPL 2100
PPP P PPP P AP +PA P + P + PT A+P VP SPL
Sbjct: 4909 PPPEEPSPPPSPLAP-----SPASPPTEPLVELPTEPLAEPPVP-------------SPL 4950
Query: 2101 MMQTMP--LQTLPAQLPPQLG 2119
+ + P + P PP+ G
Sbjct: 4951 PLASSPESARPKPRARPPEEG 4971
Score = 37.0 bits (84), Expect = 0.36
Identities = 33/100 (33%), Positives = 40/100 (40%), Gaps = 9/100 (9%)
Query: 3579 PDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSS 3638
P P + S S SPPP + P S P SR S VVSR S PP PLS
Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEES--PMSPPPEVSRLSPLPVVSRLS--PPPEESPLSPP 674
Query: 3639 STVTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDGPASP 3678
+ +S + S P +D + D PASP
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPE-----DSPASP 709
Score = 37.0 bits (84), Expect = 0.36
Identities = 31/103 (30%), Positives = 40/103 (38%), Gaps = 16/103 (15%)
Query: 2031 PLRPQTPEPPPPPP-----PPPPPPLPAAPPQPASTPAI--PAS-APPITSPTIAP-AQP 2081
PL P+ + P P P PPP A P P S P I P S P P + P QP
Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP 2389
Query: 2082 SVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPL 2124
P + ++P P + + P +PA Q PL
Sbjct: 2390 PPPESCCALP-------PRSLPSDPFSRVPASPQSQSSSQSPL 2425
Score = 37.0 bits (84), Expect = 0.36
Identities = 48/176 (27%), Positives = 71/176 (40%), Gaps = 28/176 (15%)
Query: 3105 PLQALNL---PTAYPALQGIPPVLLPG-LNSPSLPGFTPSNTALTSPK-PNLMGLPSTTV 3159
PLQ L P P L P L G + P P TP ++ PK P+ + PS+ +
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP--TPPPSSPQEPKRPSQLPSPSSQL 4330
Query: 3160 PSPGL--PTSGLPNKPSSASLSSP----TPAQATMA-------MGPQQPPQQQQQQQQPQ 3206
P+ PT KP +L P +PA A +A +GP PP + Q+P+
Sbjct: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390
Query: 3207 VQQPPPPPAAQ-----PPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVP 3257
P Q P QL ++Q+ + + K +A+ GEP+ P
Sbjct: 4391 QSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREAN---GEPIGAP 4443
Score = 36.6 bits (83), Expect = 0.48
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 2038 EPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIF 2097
+PP P P PPPP P S P+ P S P + + + +Q PLT + E
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQS--PLTPRPLSAEAFCP 2437
Query: 2098 SPL--MMQTMPLQTLPAQLPPQLGPVEPL 2124
SP+ Q+ + P P P PL
Sbjct: 2438 SPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466
Score = 36.6 bits (83), Expect = 0.48
Identities = 49/180 (27%), Positives = 68/180 (37%), Gaps = 31/180 (17%)
Query: 1621 QTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPS-SAGIAPSS-- 1677
Q + + + L A G S+G S S S +SS P + PS S G P S
Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVP----------HLLAQPSVSLGDQPGSMT 4149
Query: 1678 -NLLSQVPTESVGMPPLGNPIGANIASPSEPKEAN---------------RKKLADMIAS 1721
NLL P + + P+ N G P ++ R +L ++A
Sbjct: 4150 QNLLG--PQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAK 4207
Query: 1722 RQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFP 1781
Q + QQQQQ Q + L Q+QA Q QE Q + +Q L L FP
Sbjct: 4208 NPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFP 4267
Score = 36.2 bits (82), Expect = 0.62
Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 30/157 (19%)
Query: 2384 TPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAP-SAQPNQ 2442
+P+P + +P P ++ L+ ++EE + + E P+L + P S +P +
Sbjct: 816 SPVPEEPCLSPQPEESH--------LSPQSEE-PCLSPRPEESHLSPELEKPPLSPRPEK 866
Query: 2443 TQEKQGQ-PKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSP-- 2499
E+ GQ P PE P + + L L+ P+L +P PP PLP+ P
Sbjct: 867 PPEEPGQCPAPEELPLFPPPGEPS-----LSPLLGEPALSEP---GEPPLSPLPEELPLS 918
Query: 2500 -------SPSQLSHLPLKPLHTSTPQQLANLPPQLIP 2529
SP + PL P +P A PP L P
Sbjct: 919 PSGEPSLSPQLMPPDPLPP--PLSPIITAAAPPALSP 953
Score = 35.8 bits (81), Expect = 0.81
Identities = 53/206 (25%), Positives = 79/206 (38%), Gaps = 30/206 (14%)
Query: 3076 MAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLP 3135
++Q EL++ ++ + L +QQ + NT Q A G P +SP+
Sbjct: 2672 LSQTELEKQRQRQRLRELLIRQQ-IQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730
Query: 3136 GFTPSNT--ALTSPKPNLMGLPSTTVPSPGLPTSGLPNK-----------PSSASLSSPT 3182
+ T A T K +L+GLP + + P L P+ PSS ++S
Sbjct: 2731 QLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQ 2790
Query: 3183 PAQATMAMGPQQP-----PQQQQQQQQPQVQQPPPPP------AAQPPPTPQLPLQQQQQ 3231
+ A + P P QQQQQQ Q QQ +A+ P TP L +Q
Sbjct: 2791 LVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQAL 2850
Query: 3232 RKDKDSEKVKEKEKAHKGKGEPLPVP 3257
+ G GEP+P P
Sbjct: 2851 -----GSPLAGISTRLPGPGEPVPGP 2871
Score = 35.8 bits (81), Expect = 0.81
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 6/91 (6%)
Query: 2429 KPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAP 2488
+P+L P Q QE P+P+ P + P V P P PPP +P
Sbjct: 4260 QPQLGGFPGPQTGPLQELGAGPRPQ-----GPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
Query: 2489 P-PQCPLPQSSPSPSQLSHLPLKPLHTSTPQ 2518
P+ P SPS + L P H TP+
Sbjct: 4315 QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK 4345
Score = 35.4 bits (80), Expect = 1.1
Identities = 43/163 (26%), Positives = 60/163 (36%), Gaps = 30/163 (18%)
Query: 2031 PLRP---QTPEPPPP------PPP------PPPPPLPAAPPQPASTPAIPASAPPI---- 2071
PL P ++P PPP PPP PPP PA+PP S ++P P+
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 2072 TSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQL 2131
P + P LS E P SP + P P L P P A
Sbjct: 730 EEPQLCPRSEG---PHLSPRPEEPHLSPRPEEP---HLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 2132 YQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQ 2174
+ L+P Q + P ++L + Q + + SP E+
Sbjct: 784 EEPHLSP-----QAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Score = 35.4 bits (80), Expect = 1.1
Identities = 19/45 (42%), Positives = 21/45 (46%)
Query: 2037 PEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQP 2081
P+ P P P L A P P P + PP SPT APAQP
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP 2209
Score = 35.4 bits (80), Expect = 1.1
Identities = 42/172 (24%), Positives = 60/172 (34%), Gaps = 17/172 (9%)
Query: 3127 PGLNSPSLPGFTPSNTA------LTSPKPNLMGLPSTTVPSPGLPTS-GLPNKPSSASLS 3179
P P+L GF S ++ L P++ P T S P S GL +P
Sbjct: 2297 PSYGPPNL-GFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE---- 2351
Query: 3180 SPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEK 3239
P PAQA P P + QPP P QPPP + +
Sbjct: 2352 -PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSR 2410
Query: 3240 VKEKEKAHKGKGEPL-PVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQA 3290
V ++ PL P P + P+ +P P Y+ P++ Q+
Sbjct: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP---YSRPPSRPQS 2459
Score = 34.3 bits (77), Expect = 2.4
Identities = 57/248 (22%), Positives = 86/248 (34%), Gaps = 20/248 (8%)
Query: 3211 PPPPAAQPPPTPQ-LPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATA 3269
PP P P P L + Q Q K ++ KE PL K G+A
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG------PLQCEAKPLGKAGVQLE 427
Query: 3270 ATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQS 3329
+ APL + P + L PT+ P P A +P AL
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELP--ASPLPEALHL 485
Query: 3330 GYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQ 3389
+P+ P SP ++ LSP + ++S ++ +
Sbjct: 486 S--RPLEES----PLSPPPEES--PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS 537
Query: 3390 KVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQK-NTPREVSPLLPKLPEEPEAESKS 3448
+ P + P +P P++ P SP PE + + P E SP+ P E P +
Sbjct: 538 PPPEASPLSPPFEESPLSPPPEELPT--SPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 3449 ADSLYDPF 3456
A L+ PF
Sbjct: 596 ASRLFPPF 603
Score = 34.3 bits (77), Expect = 2.4
Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 16/110 (14%)
Query: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFS 2098
P PPP P P P+ P P+S A PP T P P+ +E P
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPT---------LEPP--- 4354
Query: 2099 PLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLY---QHQLNPTLLQQQN 2145
P + Q LGP +P P +LA+ Q L P L Q N
Sbjct: 4355 PGRVSPAAAQLADTLFSKGLGPWDP-PDNLAETQKPEQSSLVPGHLDQVN 4403
Score = 33.5 bits (75), Expect = 4.0
Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 15/141 (10%)
Query: 3569 PSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAK 3628
P LP S P P + S S SPPP + P S P ASR P + +
Sbjct: 558 PEELPTS---PPPEASRLSPPPEESPMSPPPEES--PMSPPPEASRLFPP--FEESPLSP 610
Query: 3629 PPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDGPA------SPVEGP 3682
PP PLS + S S P ++ ++S+ S P P E P
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
Query: 3683 KDPSCPKDSGLTSVGTDTFRL 3703
P P + TS + RL
Sbjct: 671 LSP--PPEESPTSPPPEASRL 689
Score = 33.1 bits (74), Expect = 5.3
Identities = 35/126 (27%), Positives = 45/126 (35%), Gaps = 12/126 (9%)
Query: 2409 LTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQ--KTNT 2466
L EA+ L + E E P E P P +E P PE P + + +
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP--PEESPLSPPPEESPTSPPPEASRLSP 469
Query: 2467 PQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSP-SP-------SQLSHLPLKPLHTSTPQ 2518
P ++LP +L P P P P+ SP SP S L PL P S P
Sbjct: 470 PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS 529
Query: 2519 QLANLP 2524
P
Sbjct: 530 PALETP 535
Score = 33.1 bits (74), Expect = 5.3
Identities = 44/145 (30%), Positives = 56/145 (38%), Gaps = 24/145 (16%)
Query: 3091 LGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKP- 3149
LGL Q+ P QAL P+ P + PG S + P P T P P
Sbjct: 2345 LGLRPQEP-----PPAQALA-----PSPPSHPDIFRPG--SYTDPYAQPPLTPRPQPPPP 2392
Query: 3150 -NLMGLPSTTVPSPGLPTSGLPNKPSSASLS-SP-TPAQATMAMGPQQPPQQQQQQQQPQ 3206
+ LP ++PS P S +P P S S S SP TP + P + Q P
Sbjct: 2393 ESCCALPPRSLPSD--PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
Query: 3207 VQQPPPPPAAQP------PPTPQLP 3225
+ P P + P PP PQ P
Sbjct: 2451 SRPPSRPQSRDPFAPLHKPPRPQPP 2475
Score = 32.7 bits (73), Expect = 6.9
Identities = 41/157 (26%), Positives = 59/157 (37%), Gaps = 18/157 (11%)
Query: 2383 STPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPN- 2441
+T P P+P + SS + E+ L +GDE K+ + A
Sbjct: 3187 ATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELP 3246
Query: 2442 -------QTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPL 2494
+ ++K+ Q K +L Q QP Q+ QQ+ Q SL S P P L
Sbjct: 3247 LLIEDLLEHEKKELQKKQQLSAQLQPAQQ----QQQQQQQHSLLSAP-----GPAQAMSL 3297
Query: 2495 PQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQ 2531
P SPS L + +Q LP L+P Q
Sbjct: 3298 PHEGSSPSLAGSQQQLSLGLAGARQ-PGLPQPLMPTQ 3333
Score = 32.7 bits (73), Expect = 6.9
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 8/85 (9%)
Query: 3376 QQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQK--------NT 3427
+QQ QLQ QQQ+ QQQQ P P A S + + S +Q+
Sbjct: 3263 KQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQ 3322
Query: 3428 PREVSPLLPKLPEEPEAESKSADSL 3452
P PL+P P + + A S+
Sbjct: 3323 PGLPQPLMPTQPPAHALQQRLAPSM 3347
Score = 32.7 bits (73), Expect = 6.9
Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 18/172 (10%)
Query: 2355 EDEEGQDDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAE 2414
+ ++ Q Q + SM + L + S S P SA S LQ + +
Sbjct: 3856 QQQQQQQQHQQQGSMAGLSHLQQSLMSHS--------GQPKLSAQPMGSLQQLQQQQQLQ 3907
Query: 2415 ELATFNSKTEAG-DEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQ----Q 2469
+ + + ++ +L + Q Q Q+ Q Q + +LQQQ+Q Q+ Q Q
Sbjct: 3908 QQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQ 3967
Query: 2470 KLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPL-HTSTPQQL 2520
+ Q + L Q P Q Q + P +P KPL H S+P L
Sbjct: 3968 QQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPG----MPAKPLQHFSSPGAL 4015
Score = 32.3 bits (72), Expect = 9.0
Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 11/65 (16%)
Query: 2029 LYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPP---------ITSPTIAPA 2079
L P P P P PP PP P P PA P + AS+ P T P
Sbjct: 2179 LAPAYPLEPRFPTAPPTYPPYPSPTG--APAQPPMLGASSRPGAGQPGEFHTTPPGTPRH 2236
Query: 2080 QPSVP 2084
QPS P
Sbjct: 2237 QPSTP 2241
Score = 32.3 bits (72), Expect = 9.0
Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 17/116 (14%)
Query: 366 GKFSGIRMEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGG---LTSSVLKTPITSVPLGP 422
G FS E+A G+ GP A LLTPS L GG L L++ ++P GP
Sbjct: 3171 GPFSSSGHTAEKA-SFGATGGPP---AHLLTPSPLSGPGGSSLLEKFELESGALTLPGGP 3226
Query: 423 LASSPTKSSEGKDSGAAE----------GEKQEVGDGDCFSEKVEPAEEEAEEEEE 468
AS A+E EK+E+ S +++PA+++ +++++
Sbjct: 3227 AASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQ 3282
Score = 32.3 bits (72), Expect = 9.0
Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 2455 QQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAP-PPQCPLPQSSPSP--SQLSHLPLKP 2511
Q+ PE T + + L PPP+ P PP PL S SP L LP +P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP 4940
Query: 2512 L---HTSTPQQLANLPPQLIP 2529
L +P LA+ P P
Sbjct: 4941 LAEPPVPSPLPLASSPESARP 4961
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 70.5 bits (171), Expect = 3e-11
Identities = 66/247 (26%), Positives = 101/247 (40%), Gaps = 23/247 (9%)
Query: 1615 MRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIA 1674
++ L T ++ L S +GT ++S +L S P ++ N +
Sbjct: 338 VQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVT 397
Query: 1675 PSSNLLSQVPT---ESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQ 1731
++N+ S + S+G +G+ + SPS + ++ +L +QQQ QQ QQ
Sbjct: 398 IAANMPSNIGAPLISSMGTTMVGSAPSTQV-SPSVQTQQHQMQLQQQQQQQQQQMQQMQQ 456
Query: 1732 QQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQ 1791
QQ QQ Q Q Q Q H+QQ LQQQ +Q Q+ L + LQLQ
Sbjct: 457 QQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQL----QQQLQQRLQLQ 512
Query: 1792 QQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILP 1851
Q QH+ + Q +P PV S +T P + Q Q HQ +
Sbjct: 513 QLQHM-------QHQSQPSPRQHSPVAS---QITSPIPAI-----GSPQPASQQHQSQIQ 557
Query: 1852 QQQQNQL 1858
Q Q Q+
Sbjct: 558 SQTQTQV 564
Score = 42.4 bits (98), Expect = 0.009
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 3365 QQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVP-PGAPSPDKDPAKESPKPEE 3423
QQ QQ LQ+ +Q QQ + +Q Q Q +Q P ASQ P P SP PA + + +
Sbjct: 499 QQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSP--QPASQQHQSQI 556
Query: 3424 QKNTPREV 3431
Q T +V
Sbjct: 557 QSQTQTQV 564
Score = 41.2 bits (95), Expect = 0.019
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 3362 QQYQQYQQSLQEAIQQQQ-----QRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAK 3416
Q QQ QQ LQ+ I QQQ Q++LQ QQ Q +Q Q + + P + PA
Sbjct: 483 QHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAI 542
Query: 3417 ESPKPEEQKN 3426
SP+P Q++
Sbjct: 543 GSPQPASQQH 552
Score = 40.8 bits (94), Expect = 0.025
Identities = 72/319 (22%), Positives = 129/319 (40%), Gaps = 63/319 (19%)
Query: 3121 IPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSS 3180
+PP L +N L N S +P T+ PSP S P+ S+S++
Sbjct: 164 MPPAQLTTINQSQLSAQLGLNLGGAS-------MPHTS-PSPPASKSATPSP--SSSINE 213
Query: 3181 PTPAQATMAMGPQQP-PQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDK---- 3235
+A A+G ++ P ++ + P+ ++ P Q P + + Q K
Sbjct: 214 EDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNP 273
Query: 3236 -----DSEKV---------KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEY 3281
+ K+ +E+++ +K K E KKE +A A A++ + +
Sbjct: 274 NATFGEVSKIVASMWDSLGEEQKQVYKRKTE---AAKKEYLKALAAYRASLVS-----KA 325
Query: 3282 AVDPAQLQALQAALTSDPTALLTSQFL------PYFVPGFSPYYAPQ-IPGALQSGYLQP 3334
A + A+ Q +++ + + LTS L + SP Q +P ++ L
Sbjct: 326 AAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTM 385
Query: 3335 MYGMEGLF---------------PYSPALSQALMGLSPGSLLQ---QYQQYQQSLQEAIQ 3376
M + P ++ ++G +P + + Q QQ+Q LQ+ Q
Sbjct: 386 RLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQ 445
Query: 3377 QQQQRQLQQQQQQKVQQQQ 3395
QQQQ+ +QQ QQQ++QQ Q
Sbjct: 446 QQQQQ-MQQMQQQQLQQHQ 463
Score = 39.7 bits (91), Expect = 0.056
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 11/113 (9%)
Query: 3146 SPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPP--------- 3196
+PKP M LP + + + +P+ + +SS A Q P
Sbjct: 379 APKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQM 438
Query: 3197 --QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAH 3247
QQQQQQQQ Q+QQ Q Q+ Q QQQ ++ ++++ H
Sbjct: 439 QLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQH 491
Score = 35.8 bits (81), Expect = 0.81
Identities = 73/347 (21%), Positives = 133/347 (38%), Gaps = 69/347 (19%)
Query: 1615 MRSVLHQTKA--------------RAAKLEAASGSSNGTGNSSSISLS-----SSTPSPV 1655
MRS++H T A ++L A G + G + S S S+TPSP
Sbjct: 149 MRSIVHMTDAARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPS 208
Query: 1656 STSGSNTFTTSNPS--SAGIAPSSNLLSQVPTESVGMPPLG--NPIGANIASPSEPKEAN 1711
S+ +N + AP S + P + P P+ A + + A
Sbjct: 209 SSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAI 268
Query: 1712 R------------KKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQV------- 1752
+ K +A M S ++Q+Q +++ + +++ + LA +A +
Sbjct: 269 KGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAE 328
Query: 1753 --QAHLQQELQQQAA---LIQSQLFNPTLLPHFPMTT--ETLLQLQQQQHLLFPFYIPSA 1805
+A + +QQ A L S L N L H ++ +TL Q + P +
Sbjct: 329 SAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLP 388
Query: 1806 EFQLNPEVSLP-----------VTSGALTLTGTGPGL-------LEDLKAQVQVPQQSHQ 1847
Q+ V++ ++S T+ G+ P + + Q+Q QQ Q
Sbjct: 389 MNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQ 448
Query: 1848 QILPQQQQNQLSIAQSHSALLQ--PSQHPEKKNKLVIKEKEKESQRE 1892
Q + Q QQ QL Q H + Q QH + + ++++++ Q++
Sbjct: 449 QQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ 495
Score = 35.0 bits (79), Expect = 1.4
Identities = 51/240 (21%), Positives = 87/240 (36%), Gaps = 27/240 (11%)
Query: 3080 ELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPAL--QGIPPVLLPGLNSPSLP-G 3136
E I+ + L + NTPL +A P Q +P + P + LP
Sbjct: 331 EAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMN 390
Query: 3137 FTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPP 3196
++ + + P+ +G P + + T+ + + PS+ S Q M + QQ
Sbjct: 391 QIVTSVTIAANMPSNIGAPLIS----SMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQ 446
Query: 3197 QQQQQQQQ-----------PQVQQPPPPPAAQPPPTPQLPLQQ--------QQQRKDKDS 3237
QQQQ QQ Q+QQ Q L QQ QQQ + +
Sbjct: 447 QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 506
Query: 3238 EKVKEKEKAH-KGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALT 3296
++++ ++ H + + +P P T+ I +P P + Q Q L+
Sbjct: 507 QRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLS 566
Score = 34.3 bits (77), Expect = 2.4
Identities = 51/196 (26%), Positives = 73/196 (37%), Gaps = 40/196 (20%)
Query: 3112 PTAYPALQGIPPVLLP--GLNSPSLPGFTPSNTALTSPK--PNLMGLPSTTVP------S 3161
P + PAL G+P VLLP L+ P PS + +P+ P + LPS T+
Sbjct: 68 PESDPAL-GMPDVLLPFQALSDP-----LPSQGSEFTPQFPPQSLDLPSITISRNLVEQD 121
Query: 3162 PGLPTSGLPNKPSSASLSS--------------PTPAQATMAMGPQQPPQQQQQQQQPQV 3207
L +SGL S +S T A + M P Q Q Q Q+
Sbjct: 122 GVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQLSAQL 181
Query: 3208 ---------QQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPK 3258
P P A TP ++ D+ + + EK +A G+ PK
Sbjct: 182 GLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEK-RAAPDSGKKPKTPK 240
Query: 3259 KEKGEAPTATAATISA 3274
K+K + P +SA
Sbjct: 241 KKKKKDPNEPQKPVSA 256
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Query: 3355 LSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQ 3395
+SP QQ+Q Q Q+ QQQ Q+ QQQ QQ QQ
Sbjct: 427 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQ 467
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 3361 LQQYQQYQQSLQEAIQQQ-QQRQLQQQQQQKVQQQQPKASQ 3400
+QQ Q Q + + IQQQ QQ+ Q QQ +QQQQ Q
Sbjct: 454 MQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQ 494
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 70.5 bits (171), Expect = 3e-11
Identities = 66/247 (26%), Positives = 101/247 (40%), Gaps = 23/247 (9%)
Query: 1615 MRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIA 1674
++ L T ++ L S +GT ++S +L S P ++ N +
Sbjct: 343 VQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVT 402
Query: 1675 PSSNLLSQVPT---ESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQ 1731
++N+ S + S+G +G+ + SPS + ++ +L +QQQ QQ QQ
Sbjct: 403 IAANMPSNIGAPLISSMGTTMVGSAPSTQV-SPSVQTQQHQMQLQQQQQQQQQQMQQMQQ 461
Query: 1732 QQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQ 1791
QQ QQ Q Q Q Q H+QQ LQQQ +Q Q+ L + LQLQ
Sbjct: 462 QQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQL----QQQLQQRLQLQ 517
Query: 1792 QQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILP 1851
Q QH+ + Q +P PV S +T P + Q Q HQ +
Sbjct: 518 QLQHM-------QHQSQPSPRQHSPVAS---QITSPIPAI-----GSPQPASQQHQSQIQ 562
Query: 1852 QQQQNQL 1858
Q Q Q+
Sbjct: 563 SQTQTQV 569
Score = 42.4 bits (98), Expect = 0.009
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 3365 QQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVP-PGAPSPDKDPAKESPKPEE 3423
QQ QQ LQ+ +Q QQ + +Q Q Q +Q P ASQ P P SP PA + + +
Sbjct: 504 QQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSP--QPASQQHQSQI 561
Query: 3424 QKNTPREV 3431
Q T +V
Sbjct: 562 QSQTQTQV 569
Score = 41.2 bits (95), Expect = 0.019
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 3362 QQYQQYQQSLQEAIQQQQ-----QRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAK 3416
Q QQ QQ LQ+ I QQQ Q++LQ QQ Q +Q Q + + P + PA
Sbjct: 488 QHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAI 547
Query: 3417 ESPKPEEQKN 3426
SP+P Q++
Sbjct: 548 GSPQPASQQH 557
Score = 40.8 bits (94), Expect = 0.025
Identities = 72/319 (22%), Positives = 129/319 (40%), Gaps = 63/319 (19%)
Query: 3121 IPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSS 3180
+PP L +N L N S +P T+ PSP S P+ S+S++
Sbjct: 169 MPPAQLTTINQSQLSAQLGLNLGGAS-------MPHTS-PSPPASKSATPSP--SSSINE 218
Query: 3181 PTPAQATMAMGPQQP-PQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDK---- 3235
+A A+G ++ P ++ + P+ ++ P Q P + + Q K
Sbjct: 219 EDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNP 278
Query: 3236 -----DSEKV---------KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEY 3281
+ K+ +E+++ +K K E KKE +A A A++ + +
Sbjct: 279 NATFGEVSKIVASMWDSLGEEQKQVYKRKTE---AAKKEYLKALAAYRASLVS-----KA 330
Query: 3282 AVDPAQLQALQAALTSDPTALLTSQFL------PYFVPGFSPYYAPQ-IPGALQSGYLQP 3334
A + A+ Q +++ + + LTS L + SP Q +P ++ L
Sbjct: 331 AAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTM 390
Query: 3335 MYGMEGLF---------------PYSPALSQALMGLSPGSLLQ---QYQQYQQSLQEAIQ 3376
M + P ++ ++G +P + + Q QQ+Q LQ+ Q
Sbjct: 391 RLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQ 450
Query: 3377 QQQQRQLQQQQQQKVQQQQ 3395
QQQQ+ +QQ QQQ++QQ Q
Sbjct: 451 QQQQQ-MQQMQQQQLQQHQ 468
Score = 39.7 bits (91), Expect = 0.056
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 11/113 (9%)
Query: 3146 SPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPP--------- 3196
+PKP M LP + + + +P+ + +SS A Q P
Sbjct: 384 APKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQM 443
Query: 3197 --QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAH 3247
QQQQQQQQ Q+QQ Q Q+ Q QQQ ++ ++++ H
Sbjct: 444 QLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQH 496
Score = 35.8 bits (81), Expect = 0.81
Identities = 73/347 (21%), Positives = 133/347 (38%), Gaps = 69/347 (19%)
Query: 1615 MRSVLHQTKA--------------RAAKLEAASGSSNGTGNSSSISLS-----SSTPSPV 1655
MRS++H T A ++L A G + G + S S S+TPSP
Sbjct: 154 MRSIVHMTDAARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPS 213
Query: 1656 STSGSNTFTTSNPS--SAGIAPSSNLLSQVPTESVGMPPLG--NPIGANIASPSEPKEAN 1711
S+ +N + AP S + P + P P+ A + + A
Sbjct: 214 SSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAI 273
Query: 1712 R------------KKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQV------- 1752
+ K +A M S ++Q+Q +++ + +++ + LA +A +
Sbjct: 274 KGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAE 333
Query: 1753 --QAHLQQELQQQAA---LIQSQLFNPTLLPHFPMTT--ETLLQLQQQQHLLFPFYIPSA 1805
+A + +QQ A L S L N L H ++ +TL Q + P +
Sbjct: 334 SAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLP 393
Query: 1806 EFQLNPEVSLP-----------VTSGALTLTGTGPGL-------LEDLKAQVQVPQQSHQ 1847
Q+ V++ ++S T+ G+ P + + Q+Q QQ Q
Sbjct: 394 MNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQ 453
Query: 1848 QILPQQQQNQLSIAQSHSALLQ--PSQHPEKKNKLVIKEKEKESQRE 1892
Q + Q QQ QL Q H + Q QH + + ++++++ Q++
Sbjct: 454 QQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ 500
Score = 35.0 bits (79), Expect = 1.4
Identities = 51/240 (21%), Positives = 87/240 (36%), Gaps = 27/240 (11%)
Query: 3080 ELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPAL--QGIPPVLLPGLNSPSLP-G 3136
E I+ + L + NTPL +A P Q +P + P + LP
Sbjct: 336 EAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMN 395
Query: 3137 FTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPP 3196
++ + + P+ +G P + + T+ + + PS+ S Q M + QQ
Sbjct: 396 QIVTSVTIAANMPSNIGAPLIS----SMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQ 451
Query: 3197 QQQQQQQQ-----------PQVQQPPPPPAAQPPPTPQLPLQQ--------QQQRKDKDS 3237
QQQQ QQ Q+QQ Q L QQ QQQ + +
Sbjct: 452 QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 511
Query: 3238 EKVKEKEKAH-KGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALT 3296
++++ ++ H + + +P P T+ I +P P + Q Q L+
Sbjct: 512 QRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLS 571
Score = 34.3 bits (77), Expect = 2.4
Identities = 51/196 (26%), Positives = 73/196 (37%), Gaps = 40/196 (20%)
Query: 3112 PTAYPALQGIPPVLLP--GLNSPSLPGFTPSNTALTSPK--PNLMGLPSTTVP------S 3161
P + PAL G+P VLLP L+ P PS + +P+ P + LPS T+
Sbjct: 73 PESDPAL-GMPDVLLPFQALSDP-----LPSQGSEFTPQFPPQSLDLPSITISRNLVEQD 126
Query: 3162 PGLPTSGLPNKPSSASLSS--------------PTPAQATMAMGPQQPPQQQQQQQQPQV 3207
L +SGL S +S T A + M P Q Q Q Q+
Sbjct: 127 GVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQLSAQL 186
Query: 3208 ---------QQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPK 3258
P P A TP ++ D+ + + EK +A G+ PK
Sbjct: 187 GLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEK-RAAPDSGKKPKTPK 245
Query: 3259 KEKGEAPTATAATISA 3274
K+K + P +SA
Sbjct: 246 KKKKKDPNEPQKPVSA 261
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/41 (43%), Positives = 22/41 (53%)
Query: 3355 LSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQ 3395
+SP QQ+Q Q Q+ QQQ Q+ QQQ QQ QQ
Sbjct: 432 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQ 472
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 3361 LQQYQQYQQSLQEAIQQQ-QQRQLQQQQQQKVQQQQPKASQ 3400
+QQ Q Q + + IQQQ QQ+ Q QQ +QQQQ Q
Sbjct: 459 MQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQ 499
>gi|45439359 triple functional domain (PTPRF interacting) [Homo
sapiens]
Length = 3097
Score = 70.5 bits (171), Expect = 3e-11
Identities = 56/187 (29%), Positives = 74/187 (39%), Gaps = 18/187 (9%)
Query: 3507 GGGGGGSGGGGGGGGGGGG----GGSYHCLACESALCGEEALSQHLESALHKHRTITRAA 3562
GGGGGGSGG GGGGG GGG GGS H S+ G + S+ S R
Sbjct: 2293 GGGGGGSGGSGGGGGSGGGGAPSGGSGHS-GGPSSCGGAPSTSRSRPS---------RIP 2342
Query: 3563 RNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVS 3622
+ + HP +L SA S A + + S P P A A P A + P +
Sbjct: 2343 QPVRHHPPVLVSSAA---SSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADA 2399
Query: 3623 RASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDT-DLSQKSDGPASPVEG 3681
S + P + + + + SG P P D T L + G ASP+
Sbjct: 2400 EGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNS 2459
Query: 3682 PKDPSCP 3688
P + P
Sbjct: 2460 PLSSAVP 2466
Score = 32.3 bits (72), Expect = 9.0
Identities = 31/141 (21%), Positives = 54/141 (38%), Gaps = 2/141 (1%)
Query: 1554 FTQKNILLVHYNSVSHLHKLKRALQESATGQPEP-TSSPDNKPFKCNTCNVAYSQSSTLE 1612
F K+ L V N S + Q P P N K T V S +
Sbjct: 1731 FNHKDSLSVSSNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKAD 1790
Query: 1613 IHMRSVLHQ-TKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSA 1671
H++ + H+ K+R + A +GS + +S++ + G ++ T S SS+
Sbjct: 1791 GHVKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSS 1850
Query: 1672 GIAPSSNLLSQVPTESVGMPP 1692
G+ + ++V +PP
Sbjct: 1851 GMQSCGEEEGEEGADAVPLPP 1871
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 70.1 bits (170), Expect = 4e-11
Identities = 135/565 (23%), Positives = 186/565 (32%), Gaps = 90/565 (15%)
Query: 3122 PPVLLPGLNSPSL--PGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLS 3179
PP+ P P PG S P GL PG T P +P +
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG--TVKPPVQPPG---T 358
Query: 3180 SPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEK 3239
+ PAQ +GP +PP QQ ++P +QP P AQPP + P QQ K +
Sbjct: 359 TKPPAQP---LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 3240 VKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDP 3299
K A + L P K G PT T P P + A Q T P
Sbjct: 416 GTPKPLAQQ---PGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470
Query: 3300 TALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGS 3359
+ L P PG PQ PG+ + QP G P P ++ PGS
Sbjct: 471 SQLPGPAKPPPQQPG-PAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKP-SPQQPGS 526
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
QQ + A Q + QQ + V Q S P+ P SP AK+ P
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ---TGSGKPLQPPTVSPS---AKQPP 580
Query: 3420 KPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEA 3479
+ P+ + PL + + L VP+ C +CQ
Sbjct: 581 ----SQGLPKTICPL-----------CNTTELLLH---VPEKANFNTCTECQ-------- 614
Query: 3480 ARSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACE--SA 3537
+ + SLC F + +L E+ + CL C+ A
Sbjct: 615 --TTVCSLCGFNPN-PHLTEV--------------------------KEWLCLNCQMKRA 645
Query: 3538 LCGEEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSP 3597
L G+ A K +T + +K P P + S A P
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ--PQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 3598 PPPSAAAPSSASPHASRKSWPQV--VSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSM 3655
PP SP A K P+ +S+ + K PS P + V QP M
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK----QPKM 759
Query: 3656 PTDDYSEESDTDLSQKSDGPASPVE 3680
S + + K D P+S V+
Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQ 784
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 2037 PEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPI 2096
P PPPPPPPPPPPP P PP P T P P +P + PL +E
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT- 2465
Query: 2097 FSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQ--LYQHQLNPT 2139
+ L +P+ + PP PV P P+ + ++ H+ P+
Sbjct: 2466 -AVLRSNGLPVTRICTTAPP---PVPPKPSSIPSGLVFTHRPEPS 2506
Score = 57.8 bits (138), Expect = 2e-07
Identities = 132/610 (21%), Positives = 198/610 (32%), Gaps = 92/610 (15%)
Query: 3116 PALQGIPPVLLPGLNSPSLPGFTPSNT--ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKP 3173
P LQ PP +P P T +++S +P + + P G P G P
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKI---KSQPPGTGKPIQGPTQTP 265
Query: 3174 SSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRK 3233
+ P A+ +Q + + +P + P PP QP TP P QQ +
Sbjct: 266 QTDHAKLPLQRDASRPQ-TKQADIVRGESVKPSLPSPSKPPIQQP--TPGKPPAQQPGHE 322
Query: 3234 DKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQA 3293
K + G +PL + + P T P + A PAQ +
Sbjct: 323 KSQPGPAKPPAQP-SGLTKPL-AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 3294 ALTSDPTALLTSQFLPYFVPGFSPYYA----PQIPGALQSGYLQPMYGMEGLFPYSPALS 3349
+ P +Q PG A P P Q G +P+ GL SPA +
Sbjct: 381 PSSEQPGPKALAQ-----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL--QSPAKA 433
Query: 3350 QA-----LMGLSPGSL-LQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPV 3403
+ PG + QQ + S Q+ + QL + QQ P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ 493
Query: 3404 PPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESKSA-DSLYDPFIVPKVQ 3462
P A P + P S KP Q+ P + SP P + P + SA S P
Sbjct: 494 PGSAKPPSQQPG--STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 3463 YKLVCRKCQAG------------FSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510
+ Q G + + ++ K++C + N E++LHVP
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTIC----PLCNTTELLLHVPEKANF 607
Query: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPS 3570
C C++ +C + + K
Sbjct: 608 N------------------TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649
Query: 3571 LLP-HSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAKP 3629
L P S+ P TA + ++A S SP P + A+P Q +S+A K
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP-------KQDLSKAPEPKK 702
Query: 3630 PSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDGPASPVEGPKDPSCPK 3689
P PPL T+ S S QP ++D + P PK+PS P
Sbjct: 703 P--PPLVKQPTLHGSP-SAKAKQP----------------PEADSLSKPAP-PKEPSVPS 742
Query: 3690 DSGLTSVGTD 3699
+ V D
Sbjct: 743 EQDKAPVADD 752
Score = 55.8 bits (133), Expect = 8e-07
Identities = 98/400 (24%), Positives = 132/400 (33%), Gaps = 75/400 (18%)
Query: 3095 AQQQGMFDNTPLQALNLPTAYPALQ-GIPPVLL--PGLNSPS-LPGFTPSNTALTSPKPN 3150
AQ G+ TP Q P P Q G P L PGL SP+ PG P+ T + P P
Sbjct: 392 AQPPGV-GKTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPG 447
Query: 3151 LM-------GLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQ 3203
+ G S P P S LP P+ P PA+ PQQP + Q
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPP----PQQPGSAKPPSQ 502
Query: 3204 QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGE 3263
QP +PPP P+PQ P + + S K ++ P P K +
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ----------PSPAKPSAQ 552
Query: 3264 APTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQI 3323
T + + P V P+ Q L L + L VP + +
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF----- 607
Query: 3324 PGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQL 3383
+L G +P L + +++ + Q +R L
Sbjct: 608 ----------------NTCTECQTTVCSLCGFNPNPHLTEVKEWL-----CLNCQMKRAL 646
Query: 3384 QQQQQQKVQQQQPKASQTPVP-----------PGAPSPDKDPAKE---SPKPEEQKNTPR 3429
QPK PV P SP KD A + S PE +K P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 3430 EVSPLL-----PKLPEEPEAESKSADSLYDPFIVPKVQYK 3464
P L K + PEA+S S + VP Q K
Sbjct: 707 VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Score = 53.9 bits (128), Expect = 3e-06
Identities = 79/321 (24%), Positives = 119/321 (37%), Gaps = 50/321 (15%)
Query: 3134 LPGFTPSNTALTSPKPNL-MGLPSTTVPSPGL--------PTSGLPNKPSSASLSSPTPA 3184
LPG +PS +L K + + PG S + NK + L S + A
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 3185 QATMAMGPQQPPQQQQQQQQ----PQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKV 3240
Q+ Q++Q + + P +QQ PP P + + PLQQ K S++
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP 244
Query: 3241 KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQA-------LQA 3293
++ + G G+P+ + PT T T A LP A P QA ++
Sbjct: 245 EKIKSQPPGTGKPI--------QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 3294 ALTSDPTALLTSQFLPYFVPGFSPYY-----APQIPGALQSGYLQPMYGMEGLF--PYSP 3346
+L S P+ Q P P P + P P A SG +P+ G P P
Sbjct: 297 SLPS-PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 3347 ALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG 3406
PG+ Q + A Q ++ +Q K Q P +TP
Sbjct: 356 ----------PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-- 403
Query: 3407 APSPDKDPAKE--SPKPEEQK 3425
P P K P ++ +PKP Q+
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQ 424
Score = 43.5 bits (101), Expect = 0.004
Identities = 55/230 (23%), Positives = 82/230 (35%), Gaps = 46/230 (20%)
Query: 3140 SNTALTSPKPNLMGLPSTTVPSPGLPTSGLP---NKPSSASLSSPTPAQATMAMGPQQPP 3196
S T P +++ LP S TSG KP+S L S +P+ +++ P+ P
Sbjct: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPAS-QLPSGSPSVSSLPAKPR--P 2392
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256
+ Q PPPPP PPP P P PLP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPP-----------------------PPPPPLPP 2429
Query: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYF-VPGF 3315
P K T+++P+ T D A T + TA+L S LP +
Sbjct: 2430 PTSPKPTILPKKKLTVASPVTTATPLFD--------AVTTLETTAVLRSNGLPVTRICTT 2481
Query: 3316 SPYYAPQIPGALQSGYL--------QPMYGMEGLFPYSPALSQALMGLSP 3357
+P P P ++ SG + +P + + P P +Q + P
Sbjct: 2482 APPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
Score = 43.1 bits (100), Expect = 0.005
Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 2038 EPPPPPPPPPPPPLPAAPP-QPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPI 2096
+PP P P PA PP Q TP A P + SP AP P+ Q P ++P
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG-PGKIPA 451
Query: 2097 FSPLMMQTMPLQTLPAQLPPQL-GPVEPLP 2125
+T QT P + P QL GP +P P
Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Score = 41.2 bits (95), Expect = 0.019
Identities = 51/216 (23%), Positives = 77/216 (35%), Gaps = 32/216 (14%)
Query: 3092 GLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLP-GLNSPSLPGFTPSN-----TALT 3145
G +++ +G P+Q P P P SP+ PG P+ T
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
Query: 3146 SPKP---------NLMGLPSTTVPSPGLPTSGLPNK----------PSSASLSSPTPAQA 3186
SPKP NL + P P + K +S +S+
Sbjct: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954
Query: 3187 TMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEK- 3245
GP P +Q QP Q PP Q PP P + +++ K +EK++ K +
Sbjct: 955 HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ 1014
Query: 3246 ---AHKGKGEPLPVPKKEKGEAPTATAATISAPLPT 3278
+ + E P P K ++ + TA A LPT
Sbjct: 1015 APTVKRTETEKKPPPIK---DSKSLTAEPQKAVLPT 1047
Score = 40.8 bits (94), Expect = 0.025
Identities = 30/127 (23%), Positives = 50/127 (39%), Gaps = 8/127 (6%)
Query: 2383 STPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQ 2442
S+ + SQA P ++ E+++ F+SK +P + P
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP---RPASDSKIISHPGP 836
Query: 2443 TQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQC----PLPQSS 2498
+ E +GQ + + Q+++ +K T P +P P P P P P PQ S
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQTVPTPQQS 895
Query: 2499 PSPSQLS 2505
P P + S
Sbjct: 896 PKPQEQS 902
Score = 40.4 bits (93), Expect = 0.033
Identities = 83/360 (23%), Positives = 124/360 (34%), Gaps = 65/360 (18%)
Query: 3130 NSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSP--------GLPTSGLPNKPSSASLSSP 3181
+SP +P A +PK +L P P P G P++ P + SLS P
Sbjct: 675 SSPQPQQTSPKKDA--APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 3182 TPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPT-----------PQLPLQQ-Q 3229
P P++P +Q + P P P P T P +P + Q
Sbjct: 733 AP--------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 3230 QQRKDKDSEKVK----EKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTME----Y 3281
Q ++K + +K + ++ GE + + P + + IS P P+ E
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 3282 AVDPAQL----QALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYG 3337
VDP Q + Q ++ P A + P PG P +P QS Q
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-TPPGPRPTAGQTVPTPQQSPKPQEQSR 903
Query: 3338 MEGL-----------FPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQ 3386
L P +P + + G G + Q + A Q Q
Sbjct: 904 RFSLNLGSITDAPKSQPTTP--QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 3387 QQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREV-SPLLPKLPEEPEAE 3445
K Q P SQ PP + P K + P P + +E +P KL EP+AE
Sbjct: 962 APMK---QAPAPSQ---PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL--EPKAE 1013
Score = 40.0 bits (92), Expect = 0.043
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 13/106 (12%)
Query: 2414 EELAT--FNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKL 2471
E+L+T F S G EKP ++ PS P+ +P+P + P
Sbjct: 2354 EQLSTTYFTSGETFGQEKPA-SQLPSGSPS-VSSLPAKPRPFFRSSSLDISAQPPPP--- 2408
Query: 2472 PQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTP 2517
P P PPP PPP P P P+ + + LP K L ++P
Sbjct: 2409 ------PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448
Score = 39.7 bits (91), Expect = 0.056
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 13/103 (12%)
Query: 2033 RPQTPEPPPPPPPPPPP-PLPAAPPQPASTPAIPASAPPITSPTI---APAQPS------ 2082
+P + +P PPP P P +P QP ST P+ P P+ +PA+PS
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAKPSAQQSTK 556
Query: 2083 -VPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPL 2124
V T P++ P SP Q P Q LP + P E L
Sbjct: 557 PVSQTGSGKPLQPPTVSPSAKQP-PSQGLPKTICPLCNTTELL 598
Score = 38.1 bits (87), Expect = 0.16
Identities = 20/84 (23%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 3370 SLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPR 3429
S +E ++++++ +Q++Q++++QQQ K+S DKD + + E K P
Sbjct: 1774 SEEEELREEEELLKEQEKQREIEQQQRKSSSKK-----SKKDKDELRAQRRRERPKTPPS 1828
Query: 3430 EVSPLLPKLPEEPEAESKSADSLY 3453
+SP+ P E ++ + L+
Sbjct: 1829 NLSPIEDASPTEELRQAAEMEELH 1852
Score = 37.0 bits (84), Expect = 0.36
Identities = 39/158 (24%), Positives = 56/158 (35%), Gaps = 22/158 (13%)
Query: 2377 PTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAP 2436
PT + P P + PA A +SA Q T + + + ++P A+ P
Sbjct: 436 PTKTPVQQPGPGKI---PAQQAGPGKTSA--QQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPP---PQAPPPQCP 2493
QP + QP +QP +PQQ P +PP P + P
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ--------PGSTKPPSQQPGSAKPSAQ 542
Query: 2494 LPQSSPSPSQLSHLPL------KPLHTSTPQQLANLPP 2525
P + +Q S P+ KPL T A PP
Sbjct: 543 QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Score = 37.0 bits (84), Expect = 0.36
Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 2/77 (2%)
Query: 2445 EKQGQPKPELQQQEQPEQKTNTPQQKLP--QLVSLPSLPQPPPQAPPPQCPLPQSSPSPS 2502
E GQ KP Q ++ P + P + SL QPPP PPP P P P P
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 2503 QLSHLPLKPLHTSTPQQ 2519
P P T P++
Sbjct: 2425 PPLPPPTSPKPTILPKK 2441
Score = 36.6 bits (83), Expect = 0.48
Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 23/180 (12%)
Query: 2376 TPTSSSCSTPMPSQAYSAPAPSANNTA-SSAFLQLTAEAEELATFNSKTEAGDEKPKLAE 2434
TP +P+Q SA T + QL A+ + ++P A+
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 2435 APSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAP------ 2488
PS QP T+ QP P +QP T P Q+ + PS QP P P
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGS-TKPPSQQPGS--AKPSAQQPSPAKPSAQQST 555
Query: 2489 ----------PPQCPL--PQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCK 2536
P Q P P + PSQ + PL +T + L ++P + C +C+
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHVPEKANFNTCTECQ 614
Score = 36.6 bits (83), Expect = 0.48
Identities = 23/83 (27%), Positives = 31/83 (37%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSM 2090
P +P + P P PPP P PPQ + P+ P T P P+ P Q
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 2091 PMELPIFSPLMMQTMPLQTLPAQ 2113
+ P P + Q PA+
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAK 548
Score = 35.4 bits (80), Expect = 1.1
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
Query: 2032 LRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091
+R ++ +P P P PP P PA P S P P P+ + PL Q
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348
Query: 2092 MELPIFSPLMMQTMPLQTLPAQLPP--QLGPVEP 2123
++ P+ P + P Q L PP Q G +P
Sbjct: 349 VKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKP 381
Score = 35.0 bits (79), Expect = 1.4
Identities = 29/113 (25%), Positives = 39/113 (34%), Gaps = 23/113 (20%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPAS------------APPITSP---- 2074
P +P +P P PP P + P PA PA P+ PP+ P
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 2075 ----TIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEP 2123
+ PA+P T P + Q + PAQ P GP +P
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP---GPAKP 410
Score = 35.0 bits (79), Expect = 1.4
Identities = 21/54 (38%), Positives = 35/54 (64%), Gaps = 3/54 (5%)
Query: 1712 RKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ--AHLQQELQQQ 1763
+KKL ++ + +Q QQ++++Q Q +Q +TLAQ Q Q++ LQQ+L QQ
Sbjct: 3254 QKKLEELQSMKQHLLFQQEEERQAQFMMRQ-ETLAQQQLQLEQIQQLQQQLHQQ 3306
Score = 34.7 bits (78), Expect = 1.8
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 12/109 (11%)
Query: 2424 EAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQ---EQPEQKTNTPQQKLPQLVSLPSL 2480
+ G EKP +E P P + G K QQ + P Q+ TP+ L P L
Sbjct: 375 QTGSEKPS-SEQPG--PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP----LAQQPGL 427
Query: 2481 PQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIP 2529
P P + P+ Q P P ++ P TS Q PP +P
Sbjct: 428 QSPAKAPGPTKTPVQQ--PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Score = 34.7 bits (78), Expect = 1.8
Identities = 37/160 (23%), Positives = 61/160 (38%), Gaps = 11/160 (6%)
Query: 398 STLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVE 457
S+ L+ T T ++S+ +S K E K A +E
Sbjct: 1717 SSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGP-----LLPTIE 1771
Query: 458 PAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGS 517
+ EE E EEEE +E+E++ E E+++ + K + DE R E P +
Sbjct: 1772 DSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKS--KKDKDELRAQRRRERPKTPPSN 1829
Query: 518 SSKKDLALSNQSISNSPLMPNVLQTLSRGTASTSSNSASS 557
S + A + + + M + L R + S S S S
Sbjct: 1830 LSPIEDASPTEELRQAAEM----EELHRSSCSEYSPSIES 1865
Score = 34.7 bits (78), Expect = 1.8
Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 16/150 (10%)
Query: 3090 VLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKP 3149
V L A+ + F ++ L P P PP P P LP TSPKP
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP-------PPTSPKP 2435
Query: 3150 NLMGLPSTTVPSPGLPTSGLPNKPSSASLSS-------PTPAQATMAMGPQQPPQQQQQQ 3202
++ TV SP + L + ++ ++ P T A P P
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 3203 QQPQVQQPPP--PPAAQPPPTPQLPLQQQQ 3230
+P P PP A P PQLP Q+
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVIPQLPTTTQK 2525
Score = 33.5 bits (75), Expect = 4.0
Identities = 42/163 (25%), Positives = 58/163 (35%), Gaps = 18/163 (11%)
Query: 2378 TSSSCSTPMPSQAYSAP--------APSANNTASSAFLQLTAEAEELATFNSKTEAGDE- 2428
T S S+ P + S P P+ A L L +A T + G+
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 2429 KPKL---AEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPP 2485
KP L ++ P QP + QP E + Q P + P L P +PP
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHE-KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 2486 QAP----PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
Q P PP PL + P P+Q + P+ LA P
Sbjct: 354 QPPGTTKPPAQPLGPAKP-PAQQTGSEKPSSEQPGPKALAQPP 395
Score = 33.5 bits (75), Expect = 4.0
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 8/99 (8%)
Query: 2035 QTPEPPPPPPPPPPPPLPAAPPQPASTPAIPA----SAPPITSPTIAPAQ---PSVPLTQ 2087
Q P P P P P P P PA A ++ T PT P+Q P+ P Q
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 2088 LSMPMELPIFSPLMMQTMPLQTLPAQLPPQL-GPVEPLP 2125
P + P P + Q + PPQ GP +P P
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521
Score = 33.1 bits (74), Expect = 5.3
Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 4/58 (6%)
Query: 2035 QTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPM 2092
+ PEP PPP P L +P A P A ++ P P +PSVP Q P+
Sbjct: 696 KAPEPKKPPPLVKQPTLHGSPSAKAKQ---PPEADSLSKPA-PPKEPSVPSEQDKAPV 749
Score = 32.7 bits (73), Expect = 6.9
Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 14/106 (13%)
Query: 2436 PSAQPNQTQEKQGQP----KPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQ 2491
P QP T + QP KP QQ + + P K L P + + P Q P P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA--LAQPPGVGKTPAQQPGPA 408
Query: 2492 CPLPQSSPSPSQLSHLP------LKPLHTSTPQQLANLPPQLIPYQ 2531
P Q +P L+ P P T TP Q P IP Q
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG--PGKIPAQ 452
Score = 32.7 bits (73), Expect = 6.9
Identities = 36/117 (30%), Positives = 48/117 (41%), Gaps = 16/117 (13%)
Query: 2424 EAGDEKPKLAEAPSAQ-----PNQTQEKQGQPKP-ELQQQEQPEQKTNTPQQ---KLPQL 2474
+ G KP LA+ P Q P T+ QP P ++ Q+ KT+ Q K P
Sbjct: 414 QVGTPKP-LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 2475 VSLPSLPQPP---PQAPPPQCPLPQSSPS--PSQLSHLPLKPLHTS-TPQQLANLPP 2525
+ P+ P P P PPPQ P PS P P +P +PQQ + P
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 70.1 bits (170), Expect = 4e-11
Identities = 135/565 (23%), Positives = 186/565 (32%), Gaps = 90/565 (15%)
Query: 3122 PPVLLPGLNSPSL--PGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLS 3179
PP+ P P PG S P GL PG T P +P +
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG--TVKPPVQPPG---T 358
Query: 3180 SPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEK 3239
+ PAQ +GP +PP QQ ++P +QP P AQPP + P QQ K +
Sbjct: 359 TKPPAQP---LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 3240 VKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDP 3299
K A + L P K G PT T P P + A Q T P
Sbjct: 416 GTPKPLAQQ---PGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470
Query: 3300 TALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGS 3359
+ L P PG PQ PG+ + QP G P P ++ PGS
Sbjct: 471 SQLPGPAKPPPQQPG-PAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKP-SPQQPGS 526
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
QQ + A Q + QQ + V Q S P+ P SP AK+ P
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ---TGSGKPLQPPTVSPS---AKQPP 580
Query: 3420 KPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEA 3479
+ P+ + PL + + L VP+ C +CQ
Sbjct: 581 ----SQGLPKTICPL-----------CNTTELLLH---VPEKANFNTCTECQ-------- 614
Query: 3480 ARSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACE--SA 3537
+ + SLC F + +L E+ + CL C+ A
Sbjct: 615 --TTVCSLCGFNPN-PHLTEV--------------------------KEWLCLNCQMKRA 645
Query: 3538 LCGEEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSP 3597
L G+ A K +T + +K P P + S A P
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ--PQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 3598 PPPSAAAPSSASPHASRKSWPQV--VSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSM 3655
PP SP A K P+ +S+ + K PS P + V QP M
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK----QPKM 759
Query: 3656 PTDDYSEESDTDLSQKSDGPASPVE 3680
S + + K D P+S V+
Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQ 784
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 2037 PEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPI 2096
P PPPPPPPPPPPP P PP P T P P +P + PL +E
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT- 2465
Query: 2097 FSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQ--LYQHQLNPT 2139
+ L +P+ + PP PV P P+ + ++ H+ P+
Sbjct: 2466 -AVLRSNGLPVTRICTTAPP---PVPPKPSSIPSGLVFTHRPEPS 2506
Score = 57.8 bits (138), Expect = 2e-07
Identities = 132/610 (21%), Positives = 198/610 (32%), Gaps = 92/610 (15%)
Query: 3116 PALQGIPPVLLPGLNSPSLPGFTPSNT--ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKP 3173
P LQ PP +P P T +++S +P + + P G P G P
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKI---KSQPPGTGKPIQGPTQTP 265
Query: 3174 SSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRK 3233
+ P A+ +Q + + +P + P PP QP TP P QQ +
Sbjct: 266 QTDHAKLPLQRDASRPQ-TKQADIVRGESVKPSLPSPSKPPIQQP--TPGKPPAQQPGHE 322
Query: 3234 DKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQA 3293
K + G +PL + + P T P + A PAQ +
Sbjct: 323 KSQPGPAKPPAQP-SGLTKPL-AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 3294 ALTSDPTALLTSQFLPYFVPGFSPYYA----PQIPGALQSGYLQPMYGMEGLFPYSPALS 3349
+ P +Q PG A P P Q G +P+ GL SPA +
Sbjct: 381 PSSEQPGPKALAQ-----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL--QSPAKA 433
Query: 3350 QA-----LMGLSPGSL-LQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPV 3403
+ PG + QQ + S Q+ + QL + QQ P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ 493
Query: 3404 PPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESKSA-DSLYDPFIVPKVQ 3462
P A P + P S KP Q+ P + SP P + P + SA S P
Sbjct: 494 PGSAKPPSQQPG--STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 3463 YKLVCRKCQAG------------FSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510
+ Q G + + ++ K++C + N E++LHVP
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTIC----PLCNTTELLLHVPEKANF 607
Query: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPS 3570
C C++ +C + + K
Sbjct: 608 N------------------TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649
Query: 3571 LLP-HSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAKP 3629
L P S+ P TA + ++A S SP P + A+P Q +S+A K
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP-------KQDLSKAPEPKK 702
Query: 3630 PSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDGPASPVEGPKDPSCPK 3689
P PPL T+ S S QP ++D + P PK+PS P
Sbjct: 703 P--PPLVKQPTLHGSP-SAKAKQP----------------PEADSLSKPAP-PKEPSVPS 742
Query: 3690 DSGLTSVGTD 3699
+ V D
Sbjct: 743 EQDKAPVADD 752
Score = 55.8 bits (133), Expect = 8e-07
Identities = 98/400 (24%), Positives = 132/400 (33%), Gaps = 75/400 (18%)
Query: 3095 AQQQGMFDNTPLQALNLPTAYPALQ-GIPPVLL--PGLNSPS-LPGFTPSNTALTSPKPN 3150
AQ G+ TP Q P P Q G P L PGL SP+ PG P+ T + P P
Sbjct: 392 AQPPGV-GKTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPG 447
Query: 3151 LM-------GLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQ 3203
+ G S P P S LP P+ P PA+ PQQP + Q
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPP----PQQPGSAKPPSQ 502
Query: 3204 QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGE 3263
QP +PPP P+PQ P + + S K ++ P P K +
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ----------PSPAKPSAQ 552
Query: 3264 APTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQI 3323
T + + P V P+ Q L L + L VP + +
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF----- 607
Query: 3324 PGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQL 3383
+L G +P L + +++ + Q +R L
Sbjct: 608 ----------------NTCTECQTTVCSLCGFNPNPHLTEVKEWL-----CLNCQMKRAL 646
Query: 3384 QQQQQQKVQQQQPKASQTPVP-----------PGAPSPDKDPAKE---SPKPEEQKNTPR 3429
QPK PV P SP KD A + S PE +K P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 3430 EVSPLL-----PKLPEEPEAESKSADSLYDPFIVPKVQYK 3464
P L K + PEA+S S + VP Q K
Sbjct: 707 VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Score = 53.9 bits (128), Expect = 3e-06
Identities = 79/321 (24%), Positives = 119/321 (37%), Gaps = 50/321 (15%)
Query: 3134 LPGFTPSNTALTSPKPNL-MGLPSTTVPSPGL--------PTSGLPNKPSSASLSSPTPA 3184
LPG +PS +L K + + PG S + NK + L S + A
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 3185 QATMAMGPQQPPQQQQQQQQ----PQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKV 3240
Q+ Q++Q + + P +QQ PP P + + PLQQ K S++
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP 244
Query: 3241 KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQA-------LQA 3293
++ + G G+P+ + PT T T A LP A P QA ++
Sbjct: 245 EKIKSQPPGTGKPI--------QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 3294 ALTSDPTALLTSQFLPYFVPGFSPYY-----APQIPGALQSGYLQPMYGMEGLF--PYSP 3346
+L S P+ Q P P P + P P A SG +P+ G P P
Sbjct: 297 SLPS-PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 3347 ALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG 3406
PG+ Q + A Q ++ +Q K Q P +TP
Sbjct: 356 ----------PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-- 403
Query: 3407 APSPDKDPAKE--SPKPEEQK 3425
P P K P ++ +PKP Q+
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQ 424
Score = 43.5 bits (101), Expect = 0.004
Identities = 55/230 (23%), Positives = 82/230 (35%), Gaps = 46/230 (20%)
Query: 3140 SNTALTSPKPNLMGLPSTTVPSPGLPTSGLP---NKPSSASLSSPTPAQATMAMGPQQPP 3196
S T P +++ LP S TSG KP+S L S +P+ +++ P+ P
Sbjct: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPAS-QLPSGSPSVSSLPAKPR--P 2392
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256
+ Q PPPPP PPP P P PLP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPP-----------------------PPPPPLPP 2429
Query: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYF-VPGF 3315
P K T+++P+ T D A T + TA+L S LP +
Sbjct: 2430 PTSPKPTILPKKKLTVASPVTTATPLFD--------AVTTLETTAVLRSNGLPVTRICTT 2481
Query: 3316 SPYYAPQIPGALQSGYL--------QPMYGMEGLFPYSPALSQALMGLSP 3357
+P P P ++ SG + +P + + P P +Q + P
Sbjct: 2482 APPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
Score = 43.1 bits (100), Expect = 0.005
Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 2038 EPPPPPPPPPPPPLPAAPP-QPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPI 2096
+PP P P PA PP Q TP A P + SP AP P+ Q P ++P
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG-PGKIPA 451
Query: 2097 FSPLMMQTMPLQTLPAQLPPQL-GPVEPLP 2125
+T QT P + P QL GP +P P
Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Score = 41.2 bits (95), Expect = 0.019
Identities = 51/216 (23%), Positives = 77/216 (35%), Gaps = 32/216 (14%)
Query: 3092 GLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLP-GLNSPSLPGFTPSN-----TALT 3145
G +++ +G P+Q P P P SP+ PG P+ T
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
Query: 3146 SPKP---------NLMGLPSTTVPSPGLPTSGLPNK----------PSSASLSSPTPAQA 3186
SPKP NL + P P + K +S +S+
Sbjct: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954
Query: 3187 TMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEK- 3245
GP P +Q QP Q PP Q PP P + +++ K +EK++ K +
Sbjct: 955 HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ 1014
Query: 3246 ---AHKGKGEPLPVPKKEKGEAPTATAATISAPLPT 3278
+ + E P P K ++ + TA A LPT
Sbjct: 1015 APTVKRTETEKKPPPIK---DSKSLTAEPQKAVLPT 1047
Score = 40.8 bits (94), Expect = 0.025
Identities = 30/127 (23%), Positives = 50/127 (39%), Gaps = 8/127 (6%)
Query: 2383 STPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQ 2442
S+ + SQA P ++ E+++ F+SK +P + P
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP---RPASDSKIISHPGP 836
Query: 2443 TQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQC----PLPQSS 2498
+ E +GQ + + Q+++ +K T P +P P P P P P PQ S
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQTVPTPQQS 895
Query: 2499 PSPSQLS 2505
P P + S
Sbjct: 896 PKPQEQS 902
Score = 40.4 bits (93), Expect = 0.033
Identities = 83/360 (23%), Positives = 124/360 (34%), Gaps = 65/360 (18%)
Query: 3130 NSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSP--------GLPTSGLPNKPSSASLSSP 3181
+SP +P A +PK +L P P P G P++ P + SLS P
Sbjct: 675 SSPQPQQTSPKKDA--APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 3182 TPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPT-----------PQLPLQQ-Q 3229
P P++P +Q + P P P P T P +P + Q
Sbjct: 733 AP--------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 3230 QQRKDKDSEKVK----EKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTME----Y 3281
Q ++K + +K + ++ GE + + P + + IS P P+ E
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 3282 AVDPAQL----QALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYG 3337
VDP Q + Q ++ P A + P PG P +P QS Q
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-TPPGPRPTAGQTVPTPQQSPKPQEQSR 903
Query: 3338 MEGL-----------FPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQ 3386
L P +P + + G G + Q + A Q Q
Sbjct: 904 RFSLNLGSITDAPKSQPTTP--QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 3387 QQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREV-SPLLPKLPEEPEAE 3445
K Q P SQ PP + P K + P P + +E +P KL EP+AE
Sbjct: 962 APMK---QAPAPSQ---PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL--EPKAE 1013
Score = 40.0 bits (92), Expect = 0.043
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 13/106 (12%)
Query: 2414 EELAT--FNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKL 2471
E+L+T F S G EKP ++ PS P+ +P+P + P
Sbjct: 2354 EQLSTTYFTSGETFGQEKPA-SQLPSGSPS-VSSLPAKPRPFFRSSSLDISAQPPPP--- 2408
Query: 2472 PQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTP 2517
P P PPP PPP P P P+ + + LP K L ++P
Sbjct: 2409 ------PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448
Score = 39.7 bits (91), Expect = 0.056
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 13/103 (12%)
Query: 2033 RPQTPEPPPPPPPPPPP-PLPAAPPQPASTPAIPASAPPITSPTI---APAQPS------ 2082
+P + +P PPP P P +P QP ST P+ P P+ +PA+PS
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAKPSAQQSTK 556
Query: 2083 -VPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPL 2124
V T P++ P SP Q P Q LP + P E L
Sbjct: 557 PVSQTGSGKPLQPPTVSPSAKQP-PSQGLPKTICPLCNTTELL 598
Score = 38.1 bits (87), Expect = 0.16
Identities = 20/84 (23%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 3370 SLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPR 3429
S +E ++++++ +Q++Q++++QQQ K+S DKD + + E K P
Sbjct: 1774 SEEEELREEEELLKEQEKQREIEQQQRKSSSKK-----SKKDKDELRAQRRRERPKTPPS 1828
Query: 3430 EVSPLLPKLPEEPEAESKSADSLY 3453
+SP+ P E ++ + L+
Sbjct: 1829 NLSPIEDASPTEELRQAAEMEELH 1852
Score = 37.0 bits (84), Expect = 0.36
Identities = 39/158 (24%), Positives = 56/158 (35%), Gaps = 22/158 (13%)
Query: 2377 PTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAP 2436
PT + P P + PA A +SA Q T + + + ++P A+ P
Sbjct: 436 PTKTPVQQPGPGKI---PAQQAGPGKTSA--QQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPP---PQAPPPQCP 2493
QP + QP +QP +PQQ P +PP P + P
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ--------PGSTKPPSQQPGSAKPSAQ 542
Query: 2494 LPQSSPSPSQLSHLPL------KPLHTSTPQQLANLPP 2525
P + +Q S P+ KPL T A PP
Sbjct: 543 QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Score = 37.0 bits (84), Expect = 0.36
Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 2/77 (2%)
Query: 2445 EKQGQPKPELQQQEQPEQKTNTPQQKLP--QLVSLPSLPQPPPQAPPPQCPLPQSSPSPS 2502
E GQ KP Q ++ P + P + SL QPPP PPP P P P P
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 2503 QLSHLPLKPLHTSTPQQ 2519
P P T P++
Sbjct: 2425 PPLPPPTSPKPTILPKK 2441
Score = 36.6 bits (83), Expect = 0.48
Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 23/180 (12%)
Query: 2376 TPTSSSCSTPMPSQAYSAPAPSANNTA-SSAFLQLTAEAEELATFNSKTEAGDEKPKLAE 2434
TP +P+Q SA T + QL A+ + ++P A+
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 2435 APSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAP------ 2488
PS QP T+ QP P +QP T P Q+ + PS QP P P
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGS-TKPPSQQPGS--AKPSAQQPSPAKPSAQQST 555
Query: 2489 ----------PPQCPL--PQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCK 2536
P Q P P + PSQ + PL +T + L ++P + C +C+
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHVPEKANFNTCTECQ 614
Score = 36.6 bits (83), Expect = 0.48
Identities = 23/83 (27%), Positives = 31/83 (37%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSM 2090
P +P + P P PPP P PPQ + P+ P T P P+ P Q
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 2091 PMELPIFSPLMMQTMPLQTLPAQ 2113
+ P P + Q PA+
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAK 548
Score = 35.4 bits (80), Expect = 1.1
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
Query: 2032 LRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091
+R ++ +P P P PP P PA P S P P P+ + PL Q
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348
Query: 2092 MELPIFSPLMMQTMPLQTLPAQLPP--QLGPVEP 2123
++ P+ P + P Q L PP Q G +P
Sbjct: 349 VKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKP 381
Score = 35.0 bits (79), Expect = 1.4
Identities = 29/113 (25%), Positives = 39/113 (34%), Gaps = 23/113 (20%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPAS------------APPITSP---- 2074
P +P +P P PP P + P PA PA P+ PP+ P
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 2075 ----TIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEP 2123
+ PA+P T P + Q + PAQ P GP +P
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP---GPAKP 410
Score = 35.0 bits (79), Expect = 1.4
Identities = 21/54 (38%), Positives = 35/54 (64%), Gaps = 3/54 (5%)
Query: 1712 RKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ--AHLQQELQQQ 1763
+KKL ++ + +Q QQ++++Q Q +Q +TLAQ Q Q++ LQQ+L QQ
Sbjct: 3254 QKKLEELQSMKQHLLFQQEEERQAQFMMRQ-ETLAQQQLQLEQIQQLQQQLHQQ 3306
Score = 34.7 bits (78), Expect = 1.8
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 12/109 (11%)
Query: 2424 EAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQ---EQPEQKTNTPQQKLPQLVSLPSL 2480
+ G EKP +E P P + G K QQ + P Q+ TP+ L P L
Sbjct: 375 QTGSEKPS-SEQPG--PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP----LAQQPGL 427
Query: 2481 PQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIP 2529
P P + P+ Q P P ++ P TS Q PP +P
Sbjct: 428 QSPAKAPGPTKTPVQQ--PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Score = 34.7 bits (78), Expect = 1.8
Identities = 37/160 (23%), Positives = 61/160 (38%), Gaps = 11/160 (6%)
Query: 398 STLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVE 457
S+ L+ T T ++S+ +S K E K A +E
Sbjct: 1717 SSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGP-----LLPTIE 1771
Query: 458 PAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGS 517
+ EE E EEEE +E+E++ E E+++ + K + DE R E P +
Sbjct: 1772 DSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKS--KKDKDELRAQRRRERPKTPPSN 1829
Query: 518 SSKKDLALSNQSISNSPLMPNVLQTLSRGTASTSSNSASS 557
S + A + + + M + L R + S S S S
Sbjct: 1830 LSPIEDASPTEELRQAAEM----EELHRSSCSEYSPSIES 1865
Score = 34.7 bits (78), Expect = 1.8
Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 16/150 (10%)
Query: 3090 VLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPKP 3149
V L A+ + F ++ L P P PP P P LP TSPKP
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP-------PPTSPKP 2435
Query: 3150 NLMGLPSTTVPSPGLPTSGLPNKPSSASLSS-------PTPAQATMAMGPQQPPQQQQQQ 3202
++ TV SP + L + ++ ++ P T A P P
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 3203 QQPQVQQPPP--PPAAQPPPTPQLPLQQQQ 3230
+P P PP A P PQLP Q+
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVIPQLPTTTQK 2525
Score = 33.5 bits (75), Expect = 4.0
Identities = 42/163 (25%), Positives = 58/163 (35%), Gaps = 18/163 (11%)
Query: 2378 TSSSCSTPMPSQAYSAP--------APSANNTASSAFLQLTAEAEELATFNSKTEAGDE- 2428
T S S+ P + S P P+ A L L +A T + G+
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 2429 KPKL---AEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPP 2485
KP L ++ P QP + QP E + Q P + P L P +PP
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHE-KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 2486 QAP----PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
Q P PP PL + P P+Q + P+ LA P
Sbjct: 354 QPPGTTKPPAQPLGPAKP-PAQQTGSEKPSSEQPGPKALAQPP 395
Score = 33.5 bits (75), Expect = 4.0
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 8/99 (8%)
Query: 2035 QTPEPPPPPPPPPPPPLPAAPPQPASTPAIPA----SAPPITSPTIAPAQ---PSVPLTQ 2087
Q P P P P P P P PA A ++ T PT P+Q P+ P Q
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 2088 LSMPMELPIFSPLMMQTMPLQTLPAQLPPQL-GPVEPLP 2125
P + P P + Q + PPQ GP +P P
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521
Score = 33.1 bits (74), Expect = 5.3
Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 4/58 (6%)
Query: 2035 QTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPM 2092
+ PEP PPP P L +P A P A ++ P P +PSVP Q P+
Sbjct: 696 KAPEPKKPPPLVKQPTLHGSPSAKAKQ---PPEADSLSKPA-PPKEPSVPSEQDKAPV 749
Score = 32.7 bits (73), Expect = 6.9
Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 14/106 (13%)
Query: 2436 PSAQPNQTQEKQGQP----KPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQ 2491
P QP T + QP KP QQ + + P K L P + + P Q P P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA--LAQPPGVGKTPAQQPGPA 408
Query: 2492 CPLPQSSPSPSQLSHLP------LKPLHTSTPQQLANLPPQLIPYQ 2531
P Q +P L+ P P T TP Q P IP Q
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG--PGKIPAQ 452
Score = 32.7 bits (73), Expect = 6.9
Identities = 36/117 (30%), Positives = 48/117 (41%), Gaps = 16/117 (13%)
Query: 2424 EAGDEKPKLAEAPSAQ-----PNQTQEKQGQPKP-ELQQQEQPEQKTNTPQQ---KLPQL 2474
+ G KP LA+ P Q P T+ QP P ++ Q+ KT+ Q K P
Sbjct: 414 QVGTPKP-LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 2475 VSLPSLPQPP---PQAPPPQCPLPQSSPS--PSQLSHLPLKPLHTS-TPQQLANLPP 2525
+ P+ P P P PPPQ P PS P P +P +PQQ + P
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP 529
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 70.1 bits (170), Expect = 4e-11
Identities = 42/105 (40%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTP-AIPASAP---------PITSPTIAPAQ 2080
P RP P PPPP PPPPPPPLP PP P+S+P P +P P+ +P + A
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLP--PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223
Query: 2081 PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLP 2125
P P P LP S L + + Q P LPP P+ LP
Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLP 268
Score = 49.7 bits (117), Expect = 5e-05
Identities = 19/28 (67%), Positives = 20/28 (71%)
Query: 2037 PEPPPPPPPPPPPPLPAAPPQPASTPAI 2064
P PPPPP PPPPPPL A PP P S P +
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPV 31
Score = 48.9 bits (115), Expect = 9e-05
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 2031 PLRPQTPEPPPPPPPP---PPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQ 2087
P+ P P P PPPPPP PPPP P+APP T ++ + P S +A Q L +
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
Query: 2088 LS 2089
++
Sbjct: 62 VT 63
Score = 48.9 bits (115), Expect = 9e-05
Identities = 39/138 (28%), Positives = 48/138 (34%), Gaps = 49/138 (35%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAA------------------------------------ 2054
P P P PPPPPPPP PPPLP A
Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLK 276
Query: 2055 --PPQPA----STPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQ 2108
P PA PA P PP S + + P+ PL ++ E P +P +
Sbjct: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP-------PPLPPK 329
Query: 2109 TLPAQLPPQLGPVEPLPA 2126
+ Q PPQ + LPA
Sbjct: 330 SPSFQAPPQKAGAQALPA 347
Score = 45.1 bits (105), Expect = 0.001
Identities = 35/116 (30%), Positives = 41/116 (35%), Gaps = 12/116 (10%)
Query: 3131 SPSLPGFTPSNTALTSPKPNLMGL-----------PSTTVPSPGLPTSGLPNKPSSASLS 3179
SP LP T S + P L P VP+P PT P P L
Sbjct: 132 SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLP 191
Query: 3180 SPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDK 3235
S +P + + P + P V PPPP PPPTP PL DK
Sbjct: 192 SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP-PLPPASVLSDK 246
Score = 44.7 bits (104), Expect = 0.002
Identities = 55/222 (24%), Positives = 68/222 (30%), Gaps = 46/222 (20%)
Query: 3084 IKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTA 3143
I A+ LG ++ G P + N+P P PP LP P LP +P T
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRP-NVPAPPPPTPPPPPPPLP----PPLPSSSPIKTP 199
Query: 3144 LTSPKPNLM--GLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQ-------- 3193
L SP L LP P P P P P + P + A+ PQ
Sbjct: 200 LVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP 259
Query: 3194 ------------------QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDK 3235
+P Q Q+P PP PP A P LP
Sbjct: 260 IPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSS 319
Query: 3236 DSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLP 3277
PLP PK +AP A + P P
Sbjct: 320 SETP------------PPLP-PKSPSFQAPPQKAGAQALPAP 348
Score = 42.0 bits (97), Expect = 0.011
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 19/132 (14%)
Query: 3112 PTAYPALQGIP-----PVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPT 3166
P YP L+ P P P LP + + + P P L G+ S++ P LP
Sbjct: 269 PCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLP- 327
Query: 3167 SGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQP--------PPPPAAQP 3218
P PS + AQA A P PP Q Q+ + +P PPP
Sbjct: 328 ---PKSPSFQAPPQKAGAQALPA--PPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR 382
Query: 3219 PPTPQLPLQQQQ 3230
PT +L + QQ
Sbjct: 383 SPTTELSSKSQQ 394
Score = 41.2 bits (95), Expect = 0.019
Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 30/146 (20%)
Query: 3080 ELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTP 3139
+++ K N+ G +A +G +TP PT G PVL P G T
Sbjct: 72 QIESSKGTNKEGGGSANTRGA--STP------PTLGDLFAGGFPVLRPAGQRDVAGGKTG 123
Query: 3140 SNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQ 3199
+P P L P+ T+ P +P P+S L + + A P +P
Sbjct: 124 QGPGSRAPSPRL---PNKTISGPLIP-------PASPRLGNTSEAHGAARTAPPRP---- 169
Query: 3200 QQQQQPQVQQPPPPPAAQPPPTPQLP 3225
P PPP PPP P LP
Sbjct: 170 --------NVPAPPPPTPPPPPPPLP 187
Score = 40.8 bits (94), Expect = 0.025
Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 14/152 (9%)
Query: 2377 PTSSSCSTPMPSQAYSAPA-PSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEA 2435
P S + S +P++ S P P A S L T+EA A +P +
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPA-----SPRLGNTSEAHGAA------RTAPPRPNVPAP 174
Query: 2436 PSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLP 2495
P P P P + P P K V P +P PP PPP P P
Sbjct: 175 PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP 234
Query: 2496 QSSPSPSQLSHLPLKPLHTSTPQQLANLPPQL 2527
P S LS +KP P L +PP L
Sbjct: 235 PPLPPASVLSDKAVKP--QLAPLHLPPIPPPL 264
Score = 39.7 bits (91), Expect = 0.056
Identities = 32/98 (32%), Positives = 39/98 (39%), Gaps = 13/98 (13%)
Query: 2033 RPQTPEPP---------PPPPPPPPPPLPAAPPQPASTPAIPA-SAPPITSPTIAP---A 2079
R P PP PPP PP P APPQ A A+PA APP + P +
Sbjct: 305 RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364
Query: 2080 QPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQ 2117
+P +L+ P P SP + Q A P Q
Sbjct: 365 RPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQ 402
Score = 36.6 bits (83), Expect = 0.48
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 2/57 (3%)
Query: 2028 KLYPLRP-QTPEPPPPPPPPPPPPLPAAPPQPASTPAIP-ASAPPITSPTIAPAQPS 2082
K P P Q + PP PPPP PP +P P +P ++ T P + P PS
Sbjct: 276 KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPS 332
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 68.6 bits (166), Expect = 1e-10
Identities = 62/233 (26%), Positives = 92/233 (39%), Gaps = 27/233 (11%)
Query: 2020 KQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPA 2079
K + H+ ++ P+ PPPPP PPPP P Q P P S P +P + +
Sbjct: 737 KHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSS 796
Query: 2080 QPSVPLTQLS-MPMELP--IFSPLMMQTMPLQTLP-AQLPPQLGPVEPLPADLAQLYQHQ 2135
P TQ+ + +LP +F P+ T P+ LP +LPP L P P + L QH
Sbjct: 797 PPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHL-PQPPEHSTPPHLNQHA 855
Query: 2136 L--NPTL---LQQQNKRPRTRITDDQLR---------VLRQYFDINNSPSEEQIKEMADK 2181
+ P L L QQ RP R + L Q + P + + + +
Sbjct: 856 VVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLED 915
Query: 2182 SGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPP 2234
P + ++ Q+ PP L +K+ S+PP P PP
Sbjct: 916 EEPPAPPLTSMQMQLYLQQLQK--------VQPPTPLLPSVKVQSQPPPPLPP 960
Score = 62.8 bits (151), Expect = 6e-09
Identities = 93/400 (23%), Positives = 146/400 (36%), Gaps = 82/400 (20%)
Query: 3116 PALQGIPPVLL-------PGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSG 3168
P + P VLL P L S + + + P P L + + P P LP
Sbjct: 903 PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPP 962
Query: 3169 LPNKPSSASLSSPTPAQATMAMGPQQPPQQQ-------------------QQQQQPQVQQ 3209
P+ P P PQ PPQQQ QQ PQ QQ
Sbjct: 963 HPSVQQQLQQQPPPPPPPQ----PQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018
Query: 3210 PPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATA 3269
PP PP Q PP PQ P + QQ + S P+ K + P +T
Sbjct: 1019 PPHPPPGQQPPPPQ-PAKPQQVIQHHHS-------------------PRHHKSD-PYSTG 1057
Query: 3270 ATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQS 3329
AP P M ++ +Q Q+L Q L + +Q
Sbjct: 1058 HLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL-------------RAASVVQP 1104
Query: 3330 GYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQ 3389
QP+ ++ +SP + SP SL + ++ +S++ + Q+ +++
Sbjct: 1105 ---QPLVVVKEEKIHSPIIRSE--PFSP-SLRPEPPKHPESIKAPVHLPQRPEMKPVDVG 1158
Query: 3390 KVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREV------SPLLPKLPEEPE 3443
+ + P+ Q PPGA PDKD K+ PK ++ + L+ K P P
Sbjct: 1159 RPVIRPPE--QNAPPPGA--PDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPS 1214
Query: 3444 AESKSADSLYDPF--IVPKVQYKLVCRKCQAGFSDEEAAR 3481
+ +KS+ ++ F + + + K QA +++E R
Sbjct: 1215 STAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKER 1254
Score = 55.5 bits (132), Expect = 1e-06
Identities = 98/414 (23%), Positives = 133/414 (32%), Gaps = 93/414 (22%)
Query: 3131 SPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSAS--------LSSPT 3182
S + GF+ S + +S + S T +P G P + +P
Sbjct: 692 SSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPA 751
Query: 3183 PAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPA----------AQPPP---------TPQ 3223
P PQQPP QQQ Q PPPPP+ + PPP PQ
Sbjct: 752 PVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
Query: 3224 LPLQ---------------QQQQRKDKDSEKVKEKEKAHKGKGEPLPVPK-----KEKGE 3263
LP Q + + + H + + P ++
Sbjct: 812 LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871
Query: 3264 APTATAATISAPLPTMEYAVDPAQLQA---LQAALTSDPTALLTSQFLPYFVPGFSPYYA 3320
P+ AA + P P AV PA Q Q + P LL + P A
Sbjct: 872 RPSNRAAAL-PPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP----------A 920
Query: 3321 PQIPGALQSGYLQPMYGMEGLFPYSPAL---SQALMGLSPGSLLQQYQQYQQSLQEAIQQ 3377
P + YLQ + ++ P P++ SQ L P QQ QQ
Sbjct: 921 PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP 980
Query: 3378 QQQRQLQQQQQ--------------QKVQQQQPKASQTP--VPPGAPSPDKDPAKESP-- 3419
Q Q QQQ Q +QQ P Q P PPG P PAK
Sbjct: 981 QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVI 1040
Query: 3420 ----KPEEQKNTP------REV-SPLLPKLPEEPEAESKSADSLYDPFIVPKVQ 3462
P K+ P RE SPL+ P+ + +S + S + PK Q
Sbjct: 1041 QHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQ 1094
Score = 51.2 bits (121), Expect = 2e-05
Identities = 38/115 (33%), Positives = 43/115 (37%), Gaps = 18/115 (15%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSM 2090
PL P PPPP PPPP P+ Q P P P QP P Q
Sbjct: 943 PLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP-----------PPPPPPQPQPPPQQQHQ 991
Query: 2091 PMELPI------FSPLMMQTMPLQ-TLPAQLPPQLGPVEPLPADLAQLYQHQLNP 2138
P P+ FS + Q P Q P PP P P PA Q+ QH +P
Sbjct: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSP 1046
Score = 46.2 bits (108), Expect = 6e-04
Identities = 23/42 (54%), Positives = 28/42 (66%)
Query: 1722 RQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQ 1763
RQ+QQQQQ+Q+QQQQQQQQ A A A Q Q+ Q + Q
Sbjct: 1282 RQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
Score = 45.8 bits (107), Expect = 8e-04
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 6/97 (6%)
Query: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPI-TSPTIAPAQPSVPLTQLSMPMELPIF 2097
PPP PP P PPP PA P + P I A+ P+ T + + T + PI
Sbjct: 250 PPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID-----PIH 304
Query: 2098 SPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQH 2134
P + P T Q PV+P D+ QH
Sbjct: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQH 341
Score = 45.4 bits (106), Expect = 0.001
Identities = 28/54 (51%), Positives = 36/54 (66%), Gaps = 4/54 (7%)
Query: 1720 ASRQQQQQQQQQQQQQQQQQQQAQTLAQA---QAQVQAHLQQELQQQAALIQSQ 1770
A R+Q+QQQQQ+Q+QQQQQQQQA +A A QAQ + Q L QQ L + +
Sbjct: 1279 ARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQ-SSQPQSMLDQQRELARKR 1331
Score = 45.1 bits (105), Expect = 0.001
Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 18/117 (15%)
Query: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQ-PASTPAIPASAP-PITSPTIAPAQPSVPLTQL 2088
P + QTP+P PPP P P PA P TP + P P+ +P P QP P
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
Query: 2089 SMPMEL--PIFS----PLMMQ---------TMPLQTLPAQLPPQLGPVEPLPADLAQ 2130
P++ PI + P+ + T P P PP L P EP L Q
Sbjct: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSL-PPEPKTTKLGQ 320
Score = 43.9 bits (102), Expect = 0.003
Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 7/101 (6%)
Query: 2422 KTEAGDEKPKLAEAPS----AQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSL 2477
+ E G KP ++ P+ + P QTQ Q P P Q P + Q +
Sbjct: 183 RKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPV---QATPHPFPAVTPDLIVQTPVM 239
Query: 2478 PSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQ 2518
+P P Q PPP P PQ P+P+ P+ +TPQ
Sbjct: 240 TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280
Score = 43.5 bits (101), Expect = 0.004
Identities = 66/264 (25%), Positives = 88/264 (33%), Gaps = 57/264 (21%)
Query: 2028 KLYPLRPQTPEPPPPP---------PP------PPPPPLP-----AAPPQPASTPAIPAS 2067
+L P PQ PE PP PP P P P A PP+PA PA+
Sbjct: 834 ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAV--- 890
Query: 2068 APPITSPTIAPAQPSVPLTQLSMPMELPIFSPL--MMQTMPLQTLPAQLPP--------- 2116
+P +T + P P Q+ + E P PL M + LQ L PP
Sbjct: 891 SPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKV 950
Query: 2117 QLGPVEPLPADLAQLYQHQL----------NPTLLQQQNKRPRTRITDDQLRVLRQYFDI 2166
Q P PLP Q QL P QQ +P R Q +
Sbjct: 951 QSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQ 1010
Query: 2167 NNSPSEEQ-------IKEMADKSGLPQKVIKHWFRNTLFKE------RQRNKDSPYNFSN 2213
P +Q + + PQ+VI+H K R SP +
Sbjct: 1011 PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHS 1070
Query: 2214 PPITSLEELKIDSRPPSPEPPKQE 2237
P ++ + L S P PK++
Sbjct: 1071 PQMSQFQSLTHQSPPQQNVQPKKQ 1094
Score = 42.4 bits (98), Expect = 0.009
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Query: 2403 SSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQP----NQTQEKQGQPKPELQQQE 2458
SS+ + ++E+ + +S+TE + K Q + Q+ Q P P QQ
Sbjct: 699 SSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP 758
Query: 2459 QPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPL 2509
P Q+ P PQ P P PPP P P +SSP P + +P+
Sbjct: 759 PPPQQPPPPPP--PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807
Score = 40.8 bits (94), Expect = 0.025
Identities = 39/169 (23%), Positives = 56/169 (33%), Gaps = 12/169 (7%)
Query: 2394 PAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPE 2453
PAP + +LQ + + + + P P Q Q +Q P P
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
Query: 2454 LQQQEQPEQKTNTPQQKLPQLVSL----------PSLPQPPPQAPPPQCPLPQSSPSPSQ 2503
Q + P Q+ + P + L + P Q PP PP Q P P P Q
Sbjct: 979 PPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQ 1038
Query: 2504 -LSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLA-FPSFEHWQEHQQ 2550
+ H H S P +L P +++ F S H QQ
Sbjct: 1039 VIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087
Score = 40.4 bits (93), Expect = 0.033
Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 10/130 (7%)
Query: 3155 PSTTVPSPGLPTSGLPNK----PSSASLSSPTPAQATMAMGPQQPPQQQQQQQ-QPQVQQ 3209
P V SP +P P K PSS+ SS + + + + + + Q+ + Q Q++
Sbjct: 464 PVVAVSSPAVPP---PTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKA 520
Query: 3210 PPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPL--PVPKKEKGEAPTA 3267
AA P P ++++ +K+K EK K KE+ + K P PKK K +
Sbjct: 521 VHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580
Query: 3268 TAATISAPLP 3277
+ + P P
Sbjct: 581 SNVSKKEPAP 590
Score = 40.0 bits (92), Expect = 0.043
Identities = 35/126 (27%), Positives = 46/126 (36%), Gaps = 16/126 (12%)
Query: 3148 KPNLMGLPSTTVPS-PGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQ 3206
KP + +P+TT S P + PN P + P PA + Q P QP
Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI--VQTPVMTVVPPQPL 247
Query: 3207 VQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPT 3266
PP PP QPPP P + V+ +P+ K K +A T
Sbjct: 248 QTPPPVPPQPQPPPAPA-------------PQPVQSHPPIIAATPQPVKTKKGVKRKADT 294
Query: 3267 ATAATI 3272
T TI
Sbjct: 295 TTPTTI 300
Score = 39.3 bits (90), Expect = 0.073
Identities = 38/128 (29%), Positives = 52/128 (40%), Gaps = 18/128 (14%)
Query: 2021 QYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPA--SAPPITSPTIAP 2078
Q+ H + P + Q P PPP PPPP PA P Q P + P ++ +
Sbjct: 1003 QFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ-PAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
Query: 2079 AQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNP 2138
A P L I SP M Q Q+L Q PPQ V+P +L Q P
Sbjct: 1062 A-----------PSPLMIHSPQMSQ---FQSLTHQSPPQQN-VQPKKQELRAASVVQPQP 1106
Query: 2139 TLLQQQNK 2146
++ ++ K
Sbjct: 1107 LVVVKEEK 1114
Score = 38.9 bits (89), Expect = 0.096
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 9/126 (7%)
Query: 2411 AEAEELATFNSKTEA-GDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQ 2469
AE ++ +SK + + + + S+ ++ E + PK + + EQK +
Sbjct: 683 AEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHH 742
Query: 2470 KLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLA----NLPP 2525
+ P P PQ PPP P P P Q P P S PQQ A + PP
Sbjct: 743 HQ----QMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798
Query: 2526 QLIPYQ 2531
I Q
Sbjct: 799 PFIATQ 804
Score = 38.9 bits (89), Expect = 0.096
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 1720 ASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQ 1770
A + +++Q+QQQQQ+Q+QQQQ Q A A A Q Q Q+ L Q +
Sbjct: 1275 AHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQR 1325
Score = 38.1 bits (87), Expect = 0.16
Identities = 23/72 (31%), Positives = 35/72 (48%)
Query: 3359 SLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKES 3418
+L Q + ++++ + QQQQQRQ QQQQQQ+ A+ P D +E
Sbjct: 1268 ALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQREL 1327
Query: 3419 PKPEEQKNTPRE 3430
+ EQ+ RE
Sbjct: 1328 ARKREQERRRRE 1339
Score = 37.4 bits (85), Expect = 0.28
Identities = 25/125 (20%), Positives = 48/125 (38%), Gaps = 2/125 (1%)
Query: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNT 2466
+ + A + ++ F+S + +++ ++ + + + P +Q++
Sbjct: 686 VDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQ 745
Query: 2467 PQQKLPQLVSLPSLP--QPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
QQ + P P QPPP PP Q P P P + + +S P +A
Sbjct: 746 MQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQV 805
Query: 2525 PQLIP 2529
P L P
Sbjct: 806 PVLEP 810
Score = 37.4 bits (85), Expect = 0.28
Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 51/181 (28%)
Query: 2397 SANNTASSAFLQLTAEAEELATFNSKTEAGDEKPK--------LAEAPSAQPNQT----Q 2444
S +++ SS+ +E E K G E+ K + +AP+ P Q Q
Sbjct: 703 SESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQ 762
Query: 2445 EKQGQPKPELQQQ-EQPEQKTNTPQQKLPQLVSLP------SLPQPPPQAP--------- 2488
+ P P+ QQQ P + PQQ P + S P +P PQ P
Sbjct: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGH 822
Query: 2489 -------------PPQCPLPQSSPSPSQLS-HLPLKP--LHTSTPQQ-------LANLPP 2525
PP P P +P L+ H + P LH + PQQ A LPP
Sbjct: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP 882
Query: 2526 Q 2526
+
Sbjct: 883 K 883
Score = 36.6 bits (83), Expect = 0.48
Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 13/176 (7%)
Query: 1490 EEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTV 1549
+E+ EE + K+ P + +S K P + P T E +
Sbjct: 554 KEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDK------- 606
Query: 1550 CKE-SFTQKNILLVHYNSVSHLHKLKRALQESATGQPE-PTSSPDNKPFKCNTCNVAYSQ 1607
CK S+ +K L + N + KL R + + +P S+PD T S
Sbjct: 607 CKPMSYEEKRQLSLDINKLPG-EKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKP--ST 663
Query: 1608 SSTLEIHMRSVLHQT-KARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNT 1662
LE ++ S L + K +A K++ +GSS G SSS S SSS S + S T
Sbjct: 664 LRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719
Score = 36.2 bits (82), Expect = 0.62
Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 18/71 (25%)
Query: 1708 KEANRKKLADMIASRQQQQQQQQQQQQQQQ------------QQQQAQTLAQAQAQVQAH 1755
+EA R++ +QQQQ+Q+QQQQQQQQ Q Q Q++ Q ++
Sbjct: 1277 EEARRRQ------EQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARK 1330
Query: 1756 LQQELQQQAAL 1766
+QE +++ A+
Sbjct: 1331 REQERRRREAM 1341
Score = 35.4 bits (80), Expect = 1.1
Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 1843 QQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGN 1902
++ Q L + Q+ ++ + +AL QP Q+ KK + KEK+KE + ++ E +
Sbjct: 504 EEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENK-K 562
Query: 1903 TGPKETLPDALKAK-------EKKELAPGGGSEP 1929
+ KE P K KKE AP P
Sbjct: 563 SKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPP 596
Score = 35.4 bits (80), Expect = 1.1
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 14/130 (10%)
Query: 2403 SSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQ--- 2459
SS ++ E ++ +S +++ D + ++A + + +E++ QQ +Q
Sbjct: 692 SSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPA 751
Query: 2460 --PEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTP 2517
P+Q PQQ P P PQ Q PPP P P S P + + P +T
Sbjct: 752 PVPQQPPPPPQQPPP-----PPPPQQQQQPPPP--PPPPSMPQQAAPAMKSSPPPFIAT- 803
Query: 2518 QQLANLPPQL 2527
Q+ L PQL
Sbjct: 804 -QVPVLEPQL 812
Score = 35.4 bits (80), Expect = 1.1
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHK 3248
QQQQQ+Q+ Q QQ A TPQ Q Q D+ E +++E+ +
Sbjct: 1285 QQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERR 1336
Score = 35.0 bits (79), Expect = 1.4
Identities = 38/156 (24%), Positives = 47/156 (30%), Gaps = 7/156 (4%)
Query: 2383 STPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPN- 2441
S P A P P+ S A Q + + DE+P S Q
Sbjct: 871 SRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL 930
Query: 2442 --QTQEKQGQPKPELQ----QQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLP 2495
Q +K P P L Q + P P + Q + P PPPQ PP
Sbjct: 931 YLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH 990
Query: 2496 QSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQ 2531
Q P P L + P PP P Q
Sbjct: 991 QPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQ 1026
Score = 33.5 bits (75), Expect = 4.0
Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 2594 PQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQL 2653
P+ P + +SP+ P T + +S S ++DS T E +R +RL EQL
Sbjct: 461 PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAE--LQEQL 518
Query: 2654 EILYQKYLLDSNP 2666
+ ++++ S P
Sbjct: 519 KAVHEQLAALSQP 531
Score = 32.7 bits (73), Expect = 6.9
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 8/127 (6%)
Query: 402 NLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEE 461
N+G S V K P T A S + S E A E E++E + E AE+
Sbjct: 1198 NMGSWASLVQKHPTTP---SSTAKSSSDSFEQFRRAAREKEERE----KALKAQAEHAEK 1250
Query: 462 EAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKK 521
E E +E E+E+ E+ +E + + + E + ++ AAA +++
Sbjct: 1251 EKERLRQERMRSREDEDALEQARRAHEE-ARRRQEQQQQQRQEQQQQQQQQAAAVAAAAT 1309
Query: 522 DLALSNQ 528
A S+Q
Sbjct: 1310 PQAQSSQ 1316
>gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]
Length = 226
Score = 67.4 bits (163), Expect = 3e-10
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 5/122 (4%)
Query: 2919 SLADPCSPSPGASGSAGKSGDSGDRPGQ----KRFRTQMTNLQLKVLKSCFNDYRTPTML 2974
S A PC PGA G + G + G+ +R RT + +QL+ L+S F + P +
Sbjct: 38 SSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIW 97
Query: 2975 ECEVLGNDIGLPKRVVQVWFQNARAKEKKSKLSMAKHFG-INQTSYEGPKTECTLCGIKY 3033
E L D GL + +QVWFQN RAK++K + S+ + ++ ++ E T C Y
Sbjct: 98 ARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSPAAFSSFLPESTACPYSY 157
Query: 3034 SA 3035
+A
Sbjct: 158 AA 159
Score = 53.1 bits (126), Expect = 5e-06
Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Query: 2606 TPTSTMNTLKRKLEEKASASPGEND-SGTGGEE--PQRDKRLRTTITPEQLEILYQKYLL 2662
TPT+T+++ A G + S GG+ P +R RTT +P QLE L +
Sbjct: 31 TPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGR 90
Query: 2663 DSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGP 2706
+ P + +A + GL + +QVWFQN RA++RK + + P
Sbjct: 91 NQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQP 134
Score = 43.1 bits (100), Expect = 0.005
Identities = 27/70 (38%), Positives = 34/70 (48%)
Query: 2230 SPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVW 2289
SP+ ++ S+R RT F+ QL L+ F N YP E L+ L I VW
Sbjct: 57 SPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVW 116
Query: 2290 FQNARQKARK 2299
FQN R K RK
Sbjct: 117 FQNRRAKQRK 126
Score = 32.3 bits (72), Expect = 9.0
Identities = 18/60 (30%), Positives = 30/60 (50%)
Query: 2146 KRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNK 2205
+R RT + QL L F N P + +A +GL + I+ WF+N K+R++ +
Sbjct: 70 RRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQER 129
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 67.4 bits (163), Expect = 3e-10
Identities = 33/75 (44%), Positives = 47/75 (62%), Gaps = 5/75 (6%)
Query: 2624 ASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKR 2683
A P E DS +P+ KR RT+ T EQL+++ ++ D+NP + L +A GL +R
Sbjct: 236 AVPSEQDS-----QPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRR 290
Query: 2684 VVQVWFQNTRARERK 2698
V+QVWFQN RAR +K
Sbjct: 291 VIQVWFQNCRARHKK 305
Score = 52.4 bits (124), Expect = 8e-06
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 2932 GSAGKSGDSGDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQ 2991
G+ DS +P KR RT T QL+V+++ F P + L + GL +RV+Q
Sbjct: 235 GAVPSEQDSQPKPA-KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQ 293
Query: 2992 VWFQNARAKEKK 3003
VWFQN RA+ KK
Sbjct: 294 VWFQNCRARHKK 305
Score = 51.2 bits (121), Expect = 2e-05
Identities = 24/74 (32%), Positives = 44/74 (59%)
Query: 2146 KRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNK 2205
KR RT T +QL+V++ F +N+P + ++++AD +GL ++VI+ WF+N + ++
Sbjct: 249 KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTP 308
Query: 2206 DSPYNFSNPPITSL 2219
P S P + L
Sbjct: 309 QHPVPPSGAPPSRL 322
Score = 45.1 bits (105), Expect = 0.001
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 8/83 (9%)
Query: 2218 SLEELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSN 2277
+LE + P+P K+ +RT FT QL+V+Q F + P ++L++
Sbjct: 232 TLEGAVPSEQDSQPKPAKR--------ARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLAD 283
Query: 2278 LLNLPTRVIVVWFQNARQKARKN 2300
+ L RVI VWFQN R + +K+
Sbjct: 284 MTGLSRRVIQVWFQNCRARHKKH 306
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 67.4 bits (163), Expect = 3e-10
Identities = 33/75 (44%), Positives = 47/75 (62%), Gaps = 5/75 (6%)
Query: 2624 ASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKR 2683
A P E DS +P+ KR RT+ T EQL+++ ++ D+NP + L +A GL +R
Sbjct: 236 AVPSEQDS-----QPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRR 290
Query: 2684 VVQVWFQNTRARERK 2698
V+QVWFQN RAR +K
Sbjct: 291 VIQVWFQNCRARHKK 305
Score = 52.4 bits (124), Expect = 8e-06
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 2932 GSAGKSGDSGDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQ 2991
G+ DS +P KR RT T QL+V+++ F P + L + GL +RV+Q
Sbjct: 235 GAVPSEQDSQPKPA-KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQ 293
Query: 2992 VWFQNARAKEKK 3003
VWFQN RA+ KK
Sbjct: 294 VWFQNCRARHKK 305
Score = 51.2 bits (121), Expect = 2e-05
Identities = 24/74 (32%), Positives = 44/74 (59%)
Query: 2146 KRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNK 2205
KR RT T +QL+V++ F +N+P + ++++AD +GL ++VI+ WF+N + ++
Sbjct: 249 KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTP 308
Query: 2206 DSPYNFSNPPITSL 2219
P S P + L
Sbjct: 309 QHPVPPSGAPPSRL 322
Score = 45.1 bits (105), Expect = 0.001
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 8/83 (9%)
Query: 2218 SLEELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSN 2277
+LE + P+P K+ +RT FT QL+V+Q F + P ++L++
Sbjct: 232 TLEGAVPSEQDSQPKPAKR--------ARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLAD 283
Query: 2278 LLNLPTRVIVVWFQNARQKARKN 2300
+ L RVI VWFQN R + +K+
Sbjct: 284 MTGLSRRVIQVWFQNCRARHKKH 306
>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 [Homo
sapiens]
Length = 818
Score = 67.0 bits (162), Expect = 3e-10
Identities = 87/322 (27%), Positives = 121/322 (37%), Gaps = 41/322 (12%)
Query: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184
PGL +PSL TP A PNL P T S G P G+P PS +LS P
Sbjct: 106 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 158
Query: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243
+ P ++ Q P + PP ++ P++ + Q + KEK
Sbjct: 159 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 218
Query: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302
P P+ E EA A + S+ PT + Q++A A + P
Sbjct: 219 R---------TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 269
Query: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357
T LP +P F P Q+ +QS QP QA SP
Sbjct: 270 QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-QTQPRIPSTDTQVQPKLQKQAQTQTSP 327
Query: 3358 GSLLQQYQQYQQSLQEAI--QQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPA 3415
L+ Q +Q Q LQ+ Q+Q Q Q+ Q Q VQ Q+ +Q V P
Sbjct: 328 EHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---------- 377
Query: 3416 KESPKPEEQKNTPREVSPLLPK 3437
+ EQ +T +VS L P+
Sbjct: 378 --PEQTHEQPHTQPQVSLLAPE 397
Score = 55.5 bits (132), Expect = 1e-06
Identities = 107/436 (24%), Positives = 152/436 (34%), Gaps = 60/436 (13%)
Query: 1718 MIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLF--NPT 1775
M + +QQQQ QQQQQQ QQ QQQQ Q QQ+LQQQ L QL +P
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQ-------------QQQLQQQQLLQLQQLLQQSPP 47
Query: 1776 LLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEV---SLPVTSGALTLTGTG---P 1829
P PM L QQ Q L ++ LN + +L + L G G P
Sbjct: 48 QAP-LPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASP 106
Query: 1830 GLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------HPEKK----NK 1879
GL Q+ + QQ PQ + L + PSQ +P+K+ +
Sbjct: 107 GLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 166
Query: 1880 LVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEKKELAPGGGSE 1928
K+ SQ + D EG E P+ + LP + K++ P E
Sbjct: 167 TTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 226
Query: 1929 PSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKLECDSC 1988
P A R + E G V + + V K+ D E LE
Sbjct: 227 PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP--EALEAQVL 284
Query: 1989 GKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP---------LRPQTPEP 2039
+ +L +++ + Q P + K + + P ++PQ +
Sbjct: 285 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 344
Query: 2040 PPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLTQLSMPMELPI 2096
P P A P QP P S P P QP + P L P + P+
Sbjct: 345 AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQVSLLAPEQTPV 401
Query: 2097 FSPLMMQTMPLQTLPA 2112
+ MP + A
Sbjct: 402 VVHVCGLEMPPDAVEA 417
Score = 49.7 bits (117), Expect = 5e-05
Identities = 74/235 (31%), Positives = 99/235 (42%), Gaps = 46/235 (19%)
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496
S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
Query: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN------------LPPQLIPYQCDQCKLAFPSFEH 2544
S P Q PL L + L N L L Y LA PS
Sbjct: 56 SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGNLRGYGMASPGLAAPSLTP 115
Query: 2545 WQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDPSNPLLASQL-LSGAIPQIPA--SS 2600
Q L+ N Q PQ +SL P + P NP SQ LSG PQ A SS
Sbjct: 116 PQ-------LATPNLQQFFPQATRQSLLGPPPVGVPMNP---SQFNLSGRNPQKQARTSS 165
Query: 2601 ATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEI 2655
+T+P+ S+ T+ +E+K+ G ++ EP+ D TPE ++
Sbjct: 166 STTPNRKDSSSQTM--PVEDKSDPPEGSEEAA----EPRMD-------TPEDQDL 207
Score = 47.4 bits (111), Expect = 3e-04
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)
Query: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040
C +C+ + + FQ H +H Q+ + H+ + + + + P
Sbjct: 515 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 574
Query: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100
CN C Y + L ++ Q H+ + +S C +CN K
Sbjct: 575 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 617
Query: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160
++HV+S H+ + ++L+ L+K + +DED C D EE ED E
Sbjct: 618 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 674
Query: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198
E + E + + S + + T SP T+ + F
Sbjct: 675 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 712
Score = 43.1 bits (100), Expect = 0.005
Identities = 24/49 (48%), Positives = 29/49 (59%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/55 (40%), Positives = 30/55 (54%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414
L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P
Sbjct: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Score = 39.7 bits (91), Expect = 0.056
Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%)
Query: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464
LQ+ A+ + + +PKL + Q P +Q Q +P+LQQ+ +P+
Sbjct: 292 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 348
Query: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
+Q PQ+ + Q P P + P Q S P + +H T Q++ L
Sbjct: 349 ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 395
Query: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569
P+ P C L P E Q+ QN+ + +R+
Sbjct: 396 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 455
Query: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620
+MP ++ L + L S + +P S + STP +T K+ L+
Sbjct: 456 REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 514
Query: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675
KAS S + + EPQ +RL +++ + Q LL P R +L+
Sbjct: 515 CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 567
Query: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733
E ++ Q+++ + R+ Q + C C FK H++S+
Sbjct: 568 EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 627
Query: 2734 -HWHEAK 2739
H +AK
Sbjct: 628 GHKDKAK 634
Score = 37.4 bits (85), Expect = 0.28
Identities = 54/261 (20%), Positives = 91/261 (34%), Gaps = 33/261 (12%)
Query: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQ-QRKDKDSEKVKEKEKAHKGKGE 3252
Q QQQ QQQQ Q+QQ LQQQQ Q++ +++ + ++ +
Sbjct: 4 QQQQQQLQQQQQQLQQ----------------LQQQQLQQQQLQQQQLLQLQQLLQQSPP 47
Query: 3253 PLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFV 3312
P+P +S LP + LQ +A + + L + L +
Sbjct: 48 QAPLP------------MAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQ-L 94
Query: 3313 PGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQQYQQYQQSL 3371
G Y PG P L + P A Q+L+G P + Q+ S
Sbjct: 95 QGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSG 154
Query: 3372 QEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREV 3431
+ +Q + ++ Q PP +P ++P+ ++ P ++
Sbjct: 155 RNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI 214
Query: 3432 SPLLPKLPEEPEAESKSADSL 3452
+ K PE E A L
Sbjct: 215 AK--EKRTPAPEPEPCEASEL 233
Score = 37.0 bits (84), Expect = 0.36
Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%)
Query: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482
+G K A S+ ++ Q P + + PE ++ P+ P+ LP P
Sbjct: 153 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 210
Query: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542
P A + P P+ P P + S LP K L +S P QL Q ++ P
Sbjct: 211 PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 266
Query: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601
Q P L +L+ + F P + +Q+ S P+I
Sbjct: 267 ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 306
Query: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623
PST T L+++ + + S
Sbjct: 307 --PSTDTQVQPKLQKQAQTQTS 326
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/50 (36%), Positives = 27/50 (54%)
Query: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753
P K+A + + + +Q+Q Q Q QQ+ + Q+Q Q Q QAQ VQ
Sbjct: 315 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 364
Score = 33.5 bits (75), Expect = 4.0
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
E + EEEE++E+EEE E E+E CK + ++ E
Sbjct: 661 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 694
>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 [Homo
sapiens]
Length = 842
Score = 67.0 bits (162), Expect = 3e-10
Identities = 85/324 (26%), Positives = 123/324 (37%), Gaps = 45/324 (13%)
Query: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184
PGL +PSL TP A PNL P T S G P G+P PS +LS P
Sbjct: 130 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
Query: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243
+ P ++ Q P + PP ++ P++ + Q + KEK
Sbjct: 183 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
Query: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302
P P+ E EA A + S+ PT + Q++A A + P
Sbjct: 243 RT---------PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
Query: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357
T LP +P F P Q+ +QS P + + P
Sbjct: 294 QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-------------QTQPRIPSTDTQVQP 339
Query: 3358 GSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKE 3417
LQ+ Q Q S + + QQ+Q Q Q QQ+ + Q+Q T P + PA+
Sbjct: 340 K--LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 397
Query: 3418 SPKP----EEQKNTPREVSPLLPK 3437
S +P EQ +T +VS L P+
Sbjct: 398 SVQPPEQTHEQPHTQPQVSLLAPE 421
Score = 56.6 bits (135), Expect = 4e-07
Identities = 111/446 (24%), Positives = 152/446 (34%), Gaps = 61/446 (13%)
Query: 1721 SRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQ------------------ 1762
S+QQQQQ QQQQQQ QQ QQQ Q Q Q LQQ LQQ
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
Query: 1763 --QAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSG 1820
Q L+ Q N L + M LL LQQ Q L F +P A + T G
Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALL-LQQLQG-LDQFAMPPATYDTAGLTMPTATLG 120
Query: 1821 ALTLTG-TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------H 1873
L G PGL Q+ + QQ PQ + L + PSQ +
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 1874 PEKK----NKLVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEK 1918
P+K+ + K+ SQ + D EG E P+ + LP + K
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 1919 KELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGE 1978
++ P EP A R + E G V + + V K+ D
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 1979 NLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP------- 2031
E LE + +L +++ + Q P + K + + P
Sbjct: 301 --EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
Query: 2032 --LRPQTPEPPPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLT 2086
++PQ + P P A P QP P S P P QP + P
Sbjct: 359 KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQV 415
Query: 2087 QLSMPMELPIFSPLMMQTMPLQTLPA 2112
L P + P+ + MP + A
Sbjct: 416 SLLAPEQTPVVVHVCGLEMPPDAVEA 441
Score = 47.4 bits (111), Expect = 3e-04
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)
Query: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040
C +C+ + + FQ H +H Q+ + H+ + + + + P
Sbjct: 539 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 598
Query: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100
CN C Y + L ++ Q H+ + +S C +CN K
Sbjct: 599 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 641
Query: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160
++HV+S H+ + ++L+ L+K + +DED C D EE ED E
Sbjct: 642 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 698
Query: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198
E + E + + S + + T SP T+ + F
Sbjct: 699 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 736
Score = 43.1 bits (100), Expect = 0.005
Identities = 24/49 (48%), Positives = 29/49 (59%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
Score = 42.0 bits (97), Expect = 0.011
Identities = 75/259 (28%), Positives = 101/259 (38%), Gaps = 70/259 (27%)
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496
S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
Query: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN--------------------LPP----------- 2525
S P Q PL L + L N +PP
Sbjct: 56 SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMP 115
Query: 2526 -----QLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDP 2579
L Y LA PS Q L+ N Q PQ +SL P + P
Sbjct: 116 TATLGNLRGYGMASPGLAAPSLTPPQ-------LATPNLQQFFPQATRQSLLGPPPVGVP 168
Query: 2580 SNPLLASQL-LSGAIPQIPA--SSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGE 2636
NP SQ LSG PQ A SS+T+P+ S+ T+ +E+K+ G ++
Sbjct: 169 MNP---SQFNLSGRNPQKQARTSSSTTPNRKDSSSQTM--PVEDKSDPPEGSEEAA---- 219
Query: 2637 EPQRDKRLRTTITPEQLEI 2655
EP+ D TPE ++
Sbjct: 220 EPRMD-------TPEDQDL 231
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/55 (40%), Positives = 30/55 (54%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414
L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P
Sbjct: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Score = 39.7 bits (91), Expect = 0.056
Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%)
Query: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464
LQ+ A+ + + +PKL + Q P +Q Q +P+LQQ+ +P+
Sbjct: 316 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 372
Query: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
+Q PQ+ + Q P P + P Q S P + +H T Q++ L
Sbjct: 373 ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 419
Query: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569
P+ P C L P E Q+ QN+ + +R+
Sbjct: 420 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 479
Query: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620
+MP ++ L + L S + +P S + STP +T K+ L+
Sbjct: 480 REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 538
Query: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675
KAS S + + EPQ +RL +++ + Q LL P R +L+
Sbjct: 539 CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 591
Query: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733
E ++ Q+++ + R+ Q + C C FK H++S+
Sbjct: 592 EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 651
Query: 2734 -HWHEAK 2739
H +AK
Sbjct: 652 GHKDKAK 658
Score = 39.3 bits (90), Expect = 0.073
Identities = 58/270 (21%), Positives = 96/270 (35%), Gaps = 27/270 (10%)
Query: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE- 3252
Q QQQ QQQQ Q+Q QL QQ QQ++ + + ++ ++ + +
Sbjct: 4 QQQQQQLQQQQQQLQ--------------QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA 49
Query: 3253 PLP------VPKKEKGEAPTATAATISAPL---PTMEYAVDPAQLQALQAALTSDPTALL 3303
PLP +P ++ + T SA L ++ A+ QLQ L T
Sbjct: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
Query: 3304 TSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQ 3362
+P G Y PG P L + P A Q+L+G P +
Sbjct: 110 AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169
Query: 3363 QYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPE 3422
Q+ S + +Q + ++ Q PP +P ++P+ +
Sbjct: 170 NPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 229
Query: 3423 EQKNTPREVSPLLPKLPEEPEAESKSADSL 3452
+ P +++ K PE E A L
Sbjct: 230 DLPPCPEDIAK--EKRTPAPEPEPCEASEL 257
Score = 37.0 bits (84), Expect = 0.36
Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%)
Query: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482
+G K A S+ ++ Q P + + PE ++ P+ P+ LP P
Sbjct: 177 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 234
Query: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542
P A + P P+ P P + S LP K L +S P QL Q ++ P
Sbjct: 235 PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 290
Query: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601
Q P L +L+ + F P + +Q+ S P+I
Sbjct: 291 ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 330
Query: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623
PST T L+++ + + S
Sbjct: 331 --PSTDTQVQPKLQKQAQTQTS 350
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/50 (36%), Positives = 27/50 (54%)
Query: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753
P K+A + + + +Q+Q Q Q QQ+ + Q+Q Q Q QAQ VQ
Sbjct: 339 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 388
Score = 33.5 bits (75), Expect = 4.0
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
E + EEEE++E+EEE E E+E CK + ++ E
Sbjct: 685 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 718
>gi|226371655 zinc finger family member 674 isoform 2 [Homo sapiens]
Length = 575
Score = 66.6 bits (161), Expect = 4e-10
Identities = 58/256 (22%), Positives = 101/256 (39%), Gaps = 29/256 (11%)
Query: 1367 CNQVFKTSAALQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIR 1426
C + F + L H ++P Y C++C F L H + H
Sbjct: 251 CAKAFSQKSTLIAHQRTHTGEKP-----------YECSECGKTFIQKSTLIKHQRTHTGE 299
Query: 1427 AATMCCLCQRSFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHT 1486
+C C ++F++ L +H E +H+ Q Y G+ L HT
Sbjct: 300 KPFVCDKCPKAFKSSYHLIRH-EKTHIR------QAFYKGIKCTTSSLIY-----QRIHT 347
Query: 1487 IIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPS-RPY 1545
+ E ++K SPT +E+ K FR + ++ + + +PY
Sbjct: 348 SEKPQCSEHGKASDEKPSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQRIHTGEKPY 407
Query: 1546 KCTVCKESFTQKNILLVHYNSVS-----HLHKLKRALQESATGQPEPTSSPDNKPFKCNT 1600
+C++C ++F+ K+ L VH+ + + + +A E +T KP+KCN
Sbjct: 408 ECSICGKTFSGKSHLSVHHRTHTGEKPYECRRCGKAFGEKSTLIVHQRMHTGEKPYKCNE 467
Query: 1601 CNVAYSQSSTLEIHMR 1616
C A+S+ S L H R
Sbjct: 468 CGKAFSEKSPLIKHQR 483
Score = 54.7 bits (130), Expect = 2e-06
Identities = 51/218 (23%), Positives = 81/218 (37%), Gaps = 57/218 (26%)
Query: 1401 YRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSH-LELSEAD 1459
Y C++C +F+ L +H + H C +C ++F K HL H E
Sbjct: 379 YECSKCGKSFRGKSHLSVHQRIHTGEKPYECSICGKTFSG----KSHLSVHHRTHTGEKP 434
Query: 1460 IQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGS 1519
+ G E T+IV + + TG E +
Sbjct: 435 YECRRCG------------KAFGEKSTLIVHQ-----------RMHTGEKPYKCNECGKA 471
Query: 1520 EPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQE 1579
+ K P ++ RPY+CT CK++F++K+ L+ H Q
Sbjct: 472 FSE------KSPLIKHQRIHTGERPYECTDCKKAFSRKSTLIKH--------------QR 511
Query: 1580 SATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRS 1617
TG+ KP+KC+ C A+S STL +H R+
Sbjct: 512 IHTGE---------KPYKCSECGKAFSVKSTLIVHHRT 540
Score = 41.2 bits (95), Expect = 0.019
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 23/75 (30%)
Query: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCN 1602
+PY+C C ++F+QK+ L+ H Q + TG+ KP++C+ C
Sbjct: 244 KPYECCECAKAFSQKSTLIAH--------------QRTHTGE---------KPYECSECG 280
Query: 1603 VAYSQSSTLEIHMRS 1617
+ Q STL H R+
Sbjct: 281 KTFIQKSTLIKHQRT 295
Score = 41.2 bits (95), Expect = 0.019
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 4/105 (3%)
Query: 641 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 700
EC +C G +L H M K KC +C + + L H + E
Sbjct: 436 ECRRCGKAFGEKSTLIVHQRMHTGE---KPYKCNECGKAFSEKSPLIKHQRIHTGERPYE 492
Query: 701 CVYCKSG-QPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIH 744
C CK L + + G KP++C C + + K L +H
Sbjct: 493 CTDCKKAFSRKSTLIKHQRIHTGEKPYKCSECGKAFSVKSTLIVH 537
Score = 40.8 bits (94), Expect = 0.025
Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 23/73 (31%)
Query: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVA 1604
YKCT C + F QK L+VH Q + TG+ KP++C C A
Sbjct: 218 YKCTECGKVFIQKANLVVH--------------QRTHTGE---------KPYECCECAKA 254
Query: 1605 YSQSSTLEIHMRS 1617
+SQ STL H R+
Sbjct: 255 FSQKSTLIAHQRT 267
Score = 33.9 bits (76), Expect = 3.1
Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 19/122 (15%)
Query: 642 CPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKC---------------PKCNWHYKYQQTL 686
C KC SS L H + K +KC P+C+ H K
Sbjct: 304 CDKCPKAFKSSYHLIRHEKTHIRQAFYKGIKCTTSSLIYQRIHTSEKPQCSEHGKASDEK 363
Query: 687 EA---HMKEKHPEPGGSCVYC-KSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLS 742
+ H + E C C KS + L+ + G KP+ C +C + + K +LS
Sbjct: 364 PSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQRIHTGEKPYECSICGKTFSGKSHLS 423
Query: 743 IH 744
+H
Sbjct: 424 VH 425
Score = 33.9 bits (76), Expect = 3.1
Identities = 20/81 (24%), Positives = 30/81 (37%), Gaps = 11/81 (13%)
Query: 1367 CNQVFKTSAALQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIR 1426
C + F + L H ++P Y+CN+C AF L H + H
Sbjct: 440 CGKAFGEKSTLIVHQRMHTGEKP-----------YKCNECGKAFSEKSPLIKHQRIHTGE 488
Query: 1427 AATMCCLCQRSFRTFQALKKH 1447
C C+++F L KH
Sbjct: 489 RPYECTDCKKAFSRKSTLIKH 509
>gi|89994742 zinc finger family member 674 isoform 1 [Homo sapiens]
Length = 581
Score = 66.6 bits (161), Expect = 4e-10
Identities = 58/256 (22%), Positives = 101/256 (39%), Gaps = 29/256 (11%)
Query: 1367 CNQVFKTSAALQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIR 1426
C + F + L H ++P Y C++C F L H + H
Sbjct: 257 CAKAFSQKSTLIAHQRTHTGEKP-----------YECSECGKTFIQKSTLIKHQRTHTGE 305
Query: 1427 AATMCCLCQRSFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHT 1486
+C C ++F++ L +H E +H+ Q Y G+ L HT
Sbjct: 306 KPFVCDKCPKAFKSSYHLIRH-EKTHIR------QAFYKGIKCTTSSLIY-----QRIHT 353
Query: 1487 IIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPS-RPY 1545
+ E ++K SPT +E+ K FR + ++ + + +PY
Sbjct: 354 SEKPQCSEHGKASDEKPSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQRIHTGEKPY 413
Query: 1546 KCTVCKESFTQKNILLVHYNSVS-----HLHKLKRALQESATGQPEPTSSPDNKPFKCNT 1600
+C++C ++F+ K+ L VH+ + + + +A E +T KP+KCN
Sbjct: 414 ECSICGKTFSGKSHLSVHHRTHTGEKPYECRRCGKAFGEKSTLIVHQRMHTGEKPYKCNE 473
Query: 1601 CNVAYSQSSTLEIHMR 1616
C A+S+ S L H R
Sbjct: 474 CGKAFSEKSPLIKHQR 489
Score = 54.7 bits (130), Expect = 2e-06
Identities = 51/218 (23%), Positives = 81/218 (37%), Gaps = 57/218 (26%)
Query: 1401 YRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSH-LELSEAD 1459
Y C++C +F+ L +H + H C +C ++F K HL H E
Sbjct: 385 YECSKCGKSFRGKSHLSVHQRIHTGEKPYECSICGKTFSG----KSHLSVHHRTHTGEKP 440
Query: 1460 IQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGS 1519
+ G E T+IV + + TG E +
Sbjct: 441 YECRRCG------------KAFGEKSTLIVHQ-----------RMHTGEKPYKCNECGKA 477
Query: 1520 EPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQE 1579
+ K P ++ RPY+CT CK++F++K+ L+ H Q
Sbjct: 478 FSE------KSPLIKHQRIHTGERPYECTDCKKAFSRKSTLIKH--------------QR 517
Query: 1580 SATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRS 1617
TG+ KP+KC+ C A+S STL +H R+
Sbjct: 518 IHTGE---------KPYKCSECGKAFSVKSTLIVHHRT 546
Score = 41.2 bits (95), Expect = 0.019
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 23/75 (30%)
Query: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCN 1602
+PY+C C ++F+QK+ L+ H Q + TG+ KP++C+ C
Sbjct: 250 KPYECCECAKAFSQKSTLIAH--------------QRTHTGE---------KPYECSECG 286
Query: 1603 VAYSQSSTLEIHMRS 1617
+ Q STL H R+
Sbjct: 287 KTFIQKSTLIKHQRT 301
Score = 41.2 bits (95), Expect = 0.019
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 4/105 (3%)
Query: 641 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 700
EC +C G +L H M K KC +C + + L H + E
Sbjct: 442 ECRRCGKAFGEKSTLIVHQRMHTGE---KPYKCNECGKAFSEKSPLIKHQRIHTGERPYE 498
Query: 701 CVYCKSG-QPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIH 744
C CK L + + G KP++C C + + K L +H
Sbjct: 499 CTDCKKAFSRKSTLIKHQRIHTGEKPYKCSECGKAFSVKSTLIVH 543
Score = 40.8 bits (94), Expect = 0.025
Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 23/73 (31%)
Query: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVA 1604
YKCT C + F QK L+VH Q + TG+ KP++C C A
Sbjct: 224 YKCTECGKVFIQKANLVVH--------------QRTHTGE---------KPYECCECAKA 260
Query: 1605 YSQSSTLEIHMRS 1617
+SQ STL H R+
Sbjct: 261 FSQKSTLIAHQRT 273
Score = 33.9 bits (76), Expect = 3.1
Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 19/122 (15%)
Query: 642 CPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKC---------------PKCNWHYKYQQTL 686
C KC SS L H + K +KC P+C+ H K
Sbjct: 310 CDKCPKAFKSSYHLIRHEKTHIRQAFYKGIKCTTSSLIYQRIHTSEKPQCSEHGKASDEK 369
Query: 687 EA---HMKEKHPEPGGSCVYC-KSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLS 742
+ H + E C C KS + L+ + G KP+ C +C + + K +LS
Sbjct: 370 PSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQRIHTGEKPYECSICGKTFSGKSHLS 429
Query: 743 IH 744
+H
Sbjct: 430 VH 431
Score = 33.9 bits (76), Expect = 3.1
Identities = 20/81 (24%), Positives = 30/81 (37%), Gaps = 11/81 (13%)
Query: 1367 CNQVFKTSAALQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIR 1426
C + F + L H ++P Y+CN+C AF L H + H
Sbjct: 446 CGKAFGEKSTLIVHQRMHTGEKP-----------YKCNECGKAFSEKSPLIKHQRIHTGE 494
Query: 1427 AATMCCLCQRSFRTFQALKKH 1447
C C+++F L KH
Sbjct: 495 RPYECTDCKKAFSRKSTLIKH 515
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 66.2 bits (160), Expect = 6e-10
Identities = 99/369 (26%), Positives = 139/369 (37%), Gaps = 57/369 (15%)
Query: 3091 LGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSL-PGFTPSNTALTSPKP 3149
LG +Q+ + P++ + + + Y P P L PS P F+ +N+AL
Sbjct: 344 LGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSAL----- 398
Query: 3150 NLMGLPSTTVPSPGLPTS-GLPNKPSSASLSSPTPAQAT-------MAMGPQQPPQQQQQ 3201
ST+ P P +P S P S AS + P+ + + +A QQ + QQ
Sbjct: 399 ------STSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQH 452
Query: 3202 QQQ---------PQVQQPPPPPAAQPP-PTPQLPLQQQQQRKD--------KDSEKVKEK 3243
QQQ P P P P Q P+P Q + KV
Sbjct: 453 QQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMAN 512
Query: 3244 EKAHKG---KGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPT 3300
G +G L V ++K + + + I+ P P ME P Q +
Sbjct: 513 YMYKAGPSAQGGHLDVLMQQKPQ--DLSRSFINNPHPAME----PRQGNTKPLFHFNSDQ 566
Query: 3301 ALLTSQFLPYFVPGFSP----YYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLS 3356
A +Q +P +P + +Y Q Q Q + Q
Sbjct: 567 A---NQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQ 620
Query: 3357 PGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAK 3416
S+ Q QQ QQS A QQQQQ+Q QQQQQQ+ QQQQ + Q P A S P
Sbjct: 621 QSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL 680
Query: 3417 ESPKPEEQK 3425
SP P +QK
Sbjct: 681 RSPLPLQQK 689
Score = 65.5 bits (158), Expect = 1e-09
Identities = 115/459 (25%), Positives = 171/459 (37%), Gaps = 65/459 (14%)
Query: 1454 ELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDL---EDKQSPTGS-- 1508
+L + ++Q+L+ L N + M D L +++D DL + +P S
Sbjct: 300 QLMDPELQELFNEL-TNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLP 358
Query: 1509 ----------DSGSVQEDSGSEPKRALPFRKGPNFTM-EKFLDPSRPYKCTVCKESFTQK 1557
G Q SGS R P GP F+M L S P ++ Q
Sbjct: 359 MEKIVIKSEYSPGLTQGPSGSPQLR--PPSAGPAFSMANSALSTSSPIPSVPQSQAQPQT 416
Query: 1558 NI----LLVHYNSVSHLHKLKRAL----QESATGQPEPTSSPDNKPFKCNTCNVAYSQSS 1609
L + VSH +LK+ Q + Q + P N ++ +
Sbjct: 417 GSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFG 476
Query: 1610 TLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGS-NTFTTSNP 1668
+I S QT + + G + G+G S ++ P + G + P
Sbjct: 477 QEKIPSPSFGQQTFSPQSS--PMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKP 534
Query: 1669 SSAGIAPSSNLLSQVPTESVGMPPLG--NPIGANIASPSEPKEANRKKLADMIASRQQQQ 1726
+ +N + PL N AN PS N+ L +QQQQ
Sbjct: 535 QDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQ 594
Query: 1727 QQQQQQQQQQQQQQQAQTLAQAQAQVQAHL--QQELQQQAALIQSQLFNPTLLPHFPMTT 1784
QQQQQQQQQQQQQQQ Q Q Q Q Q+ + QQ+ QQQ+++ Q
Sbjct: 595 QQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ 654
Query: 1785 ETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQ 1844
+ Q QQQQ PS++ P SLP + P L L Q ++ Q
Sbjct: 655 QQQQQQQQQQQ-------PSSQ----PAQSLP----------SQPLLRSPLPLQQKLLLQ 693
Query: 1845 SHQ---------QILPQQQQNQLSIAQSHSALLQPSQHP 1874
Q Q+ QQ+Q+Q S+ ++ PS +P
Sbjct: 694 QMQNQPIAGMGYQVSQQQRQDQHSVVGQNTG-PSPSPNP 731
Score = 50.4 bits (119), Expect = 3e-05
Identities = 62/270 (22%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 3177 SLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKD 3236
S + P+ T QQ QQQQQQQQ Q QQ Q + QQQQQ++
Sbjct: 577 SQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSI 636
Query: 3237 SEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALT 3296
S + +++++ + + + ++++ + ++ S P + + P Q + L +
Sbjct: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
Query: 3297 SDPTALLTSQF----------LPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP 3346
+ P A + Q + G SP P SGY+ +
Sbjct: 697 NQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL-------- 748
Query: 3347 ALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG 3406
L+Q LMG +Q QRQ+ +Q+QQ + QQQ A + P
Sbjct: 749 -LNQQLMGK--------------------KQTLQRQIMEQKQQLLLQQQMLADAEKIAP- 786
Query: 3407 APSPDKDPAKESPKPEEQKNTPREVSPLLP 3436
D+ S P + K+ R V + P
Sbjct: 787 ---QDQINRHLSRPPPDYKDQRRNVGNMQP 813
Score = 41.6 bits (96), Expect = 0.015
Identities = 80/343 (23%), Positives = 126/343 (36%), Gaps = 38/343 (11%)
Query: 1546 KCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVA- 1604
K T+ ++ QK LL+ ++ K+ Q + P PD K + N N+
Sbjct: 757 KQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPP---PDYKDQRRNVGNMQP 813
Query: 1605 ---YSQ-SSTLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSP-VSTSG 1659
YS SST+ ++ L + L T NSS +S S T P +ST+
Sbjct: 814 TAQYSGGSSTISLNSNQALANPVSTHTIL---------TPNSSLLSTSHGTRMPSLSTAV 864
Query: 1660 SNTFTTSN-----PSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKK 1714
N N P++ + N L+Q + NP+ + P +N
Sbjct: 865 QNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPM---MPRPPTLGPSNNNN 921
Query: 1715 LADM----IASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQE--LQQQAALIQ 1768
+A + + QQ + Q+ + + + QE +QQ AL
Sbjct: 922 VATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTS 981
Query: 1769 SQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSL-PVTSGALTLTGT 1827
+ + PT P ++L Q Q P QL P V + P+ + TL G
Sbjct: 982 AGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPN--QLTPAVQMRPMNQMSQTLNGQ 1039
Query: 1828 GPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQP 1870
G L L + P Q QILP Q+ + QS + + QP
Sbjct: 1040 TMGPLRGLNLR---PNQLSTQILPNLNQSGTGLNQSRTGINQP 1079
Score = 38.5 bits (88), Expect = 0.13
Identities = 36/149 (24%), Positives = 56/149 (37%), Gaps = 13/149 (8%)
Query: 3505 PTGGGGGGSGGGGGGGGG---GGGGGSYHCLACESALCGEEALSQHLESALHKHRTITRA 3561
P GG GG SG G GGG L A+C + LS + + R
Sbjct: 10 PAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRE 69
Query: 3562 ARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVV 3621
+ + SL+ H + + + A + +PPPP AA P+++ Q
Sbjct: 70 RESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAAS----------QAA 119
Query: 3622 SRASAAKPPSFPPLSSSSTVTSSSCSTSG 3650
+ A+ PP + + SS+ SG
Sbjct: 120 ATAAPPPPPDYHHHHQQHLLNSSNNGGSG 148
Score = 37.7 bits (86), Expect = 0.21
Identities = 37/136 (27%), Positives = 53/136 (38%), Gaps = 27/136 (19%)
Query: 2439 QPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPS--------LPQPPPQAPPP 2490
Q Q Q++Q Q + + QQQ+Q +Q + + QQ+ Q S+ + Q Q
Sbjct: 598 QQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQ 657
Query: 2491 QCPLPQSSPSPSQLSHLPLKPLHTS--------TPQQLANLPPQLIPYQCDQCKLAFPSF 2542
Q Q PS LP +PL S QQ+ N P + YQ Q
Sbjct: 658 QQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQ-------- 709
Query: 2543 EHWQEHQQLHFLSAQN 2558
Q+ Q H + QN
Sbjct: 710 ---QQRQDQHSVVGQN 722
Score = 35.8 bits (81), Expect = 0.81
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 3/51 (5%)
Query: 2435 APSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPP 2485
A Q Q Q++Q Q + + QQQ+Q +Q ++ P Q LP S P L P P
Sbjct: 638 AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLP---SQPLLRSPLP 685
Score = 33.9 bits (76), Expect = 3.1
Identities = 24/90 (26%), Positives = 36/90 (40%)
Query: 2442 QTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSP 2501
Q Q++Q Q + + QQQ+Q +Q+ QQ+ Q S S Q Q Q
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
Query: 2502 SQLSHLPLKPLHTSTPQQLANLPPQLIPYQ 2531
Q + QQ ++ P Q +P Q
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQ 677
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 66.2 bits (160), Expect = 6e-10
Identities = 53/177 (29%), Positives = 76/177 (42%), Gaps = 24/177 (13%)
Query: 2628 ENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQV 2687
+ND G KR RTTIT +QLE L Y P R + + ++ E GL RVVQV
Sbjct: 149 QNDDSEAGA-----KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQV 203
Query: 2688 WFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTA--------------LEAHIRSR 2733
WFQN RA+E+ R A HR F +++ +++ + ++ + R
Sbjct: 204 WFQNRRAKEK----RLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFR 259
Query: 2734 HWHEAKRAGYNLTLSAMLLDCDGGLQMKGDI-FDGTSFSHLPPSSSDGQGVPLSPVS 2789
G+ + + D GG M G DGT S+ G+P SP S
Sbjct: 260 EDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSS 316
Score = 59.3 bits (142), Expect = 7e-08
Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 10/123 (8%)
Query: 2945 GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKS 3004
G KR RT +T QL+ LK+ + + P E L ++ GL RVVQVWFQN RAKEK+
Sbjct: 156 GAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL 215
Query: 3005 KLSMAKH-FG--------INQTSYEGPKTECTLCGIKYSARLSVRDHIFSQ-QHISKVKD 3054
K +H +G +S + ++ CG+ S D I S+ H +++
Sbjct: 216 KKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYG 275
Query: 3055 TIG 3057
+G
Sbjct: 276 NVG 278
Score = 47.8 bits (112), Expect = 2e-04
Identities = 21/62 (33%), Positives = 38/62 (61%)
Query: 2146 KRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNK 2205
KRPRT IT QL L+ + + P+ ++++ ++GL +V++ WF+N KE++ K
Sbjct: 158 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217
Query: 2206 DS 2207
D+
Sbjct: 218 DA 219
Score = 43.5 bits (101), Expect = 0.004
Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 31/234 (13%)
Query: 2101 MMQ--TMPLQTLPAQLPPQLG-PVEPLPADLAQLYQHQLNPTLLQQQNKRPRT---RITD 2154
MMQ T+P + LP LG P++ +P A QH L+ +L+ ++ + + D
Sbjct: 1 MMQSATVPAEGAVKGLPEMLGVPMQQIP-QCAGCNQHILDKFILKVLDRHWHSSCLKCAD 59
Query: 2155 DQLRVLRQYFDINNSP--SEEQIKEMADK-----SGLPQ-KVIK---------HWFRNTL 2197
Q+++ + F S E+ K K G+P +V++ H F +
Sbjct: 60 CQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACII 119
Query: 2198 FKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVL 2257
+ D Y + + E+ + + E G+KR RT T QL L
Sbjct: 120 CNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEA------GAKRP-RTTITAKQLETL 172
Query: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGE 2311
++ + + P EQLS+ L RV+ VWFQN R K ++ ++ G + G+
Sbjct: 173 KNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQ 226
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 65.9 bits (159), Expect = 7e-10
Identities = 48/123 (39%), Positives = 59/123 (47%), Gaps = 21/123 (17%)
Query: 1722 RQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFP 1781
+QQQQQQQQQQQQQQQQQQQ Q Q + QQ+ QQQ Q +F LL
Sbjct: 167 QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL---- 222
Query: 1782 MTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTL-----TGTGPGLLEDLK 1836
+ QLQQQQHLL Q +S+P AL + G P ++ L
Sbjct: 223 ----QMQQLQQQQHLL--------SLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLW 270
Query: 1837 AQV 1839
+V
Sbjct: 271 KEV 273
Score = 52.4 bits (124), Expect = 8e-06
Identities = 29/73 (39%), Positives = 44/73 (60%), Gaps = 11/73 (15%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
LLQQ QQ QQ Q+ QQQQQ+Q QQQQQQ+ QQQQ + Q + P K++
Sbjct: 150 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------QHPGKQAK 198
Query: 3420 KPEEQKNTPREVS 3432
+ ++Q+ ++++
Sbjct: 199 EQQQQQQQQQQLA 211
Score = 47.0 bits (110), Expect = 4e-04
Identities = 54/189 (28%), Positives = 76/189 (40%), Gaps = 46/189 (24%)
Query: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQEL------------QQQAALIQSQL 1771
QQQQ Q +Q QQQ + + + Q LQ + QQ ++Q Q+
Sbjct: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV 112
Query: 1772 FNPTLLPHFPMTTETLLQLQQ----QQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGT 1827
+P L + LLQ QQ QQ L FY E QL+ +
Sbjct: 113 LSPQQL-------QALLQQQQAVMLQQQQLQEFYKKQQE-QLHLQ--------------- 149
Query: 1828 GPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEK 1887
LL+ + Q Q QQ QQ QQQQ Q Q Q QHP K+ KE+++
Sbjct: 150 ---LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQ----AKEQQQ 202
Query: 1888 ESQRERDSA 1896
+ Q+++ A
Sbjct: 203 QQQQQQQLA 211
Score = 45.8 bits (107), Expect = 8e-04
Identities = 47/146 (32%), Positives = 53/146 (36%), Gaps = 63/146 (43%)
Query: 1723 QQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPM 1782
QQQQQQQQQQQQQQQQQQQ Q Q Q Q QQ+ QQQ
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQQQ------------------- 187
Query: 1783 TTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVP 1842
QQQQH G E + Q Q
Sbjct: 188 --------QQQQH-------------------------------PGKQAKEQQQQQQQQQ 208
Query: 1843 QQSHQQILPQQQQNQLSIAQSHSALL 1868
Q + QQ++ QQQ Q+ Q LL
Sbjct: 209 QLAAQQLVFQQQLLQMQQLQQQQHLL 234
Score = 40.4 bits (93), Expect = 0.033
Identities = 23/42 (54%), Positives = 28/42 (66%), Gaps = 3/42 (7%)
Query: 3362 QQYQQYQQSLQEAIQQQQQ---RQLQQQQQQKVQQQQPKASQ 3400
QQ QQ QQ Q+ QQQQQ +Q ++QQQQ+ QQQQ A Q
Sbjct: 173 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
Score = 40.0 bits (92), Expect = 0.043
Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 19/134 (14%)
Query: 3193 QQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE 3252
QQ QQQQQQQQ Q QQ QQQQQ++ + ++ +++++ H GK
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQ--------------QQQQQQQQQQQQQQQQQQQQHPGKQA 197
Query: 3253 PLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQ-AALTSDP--TALLTSQFLP 3309
++++ + A L M+ L +LQ L S P A L Q LP
Sbjct: 198 KEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLP 257
Query: 3310 YFVPGFSPYYAPQI 3323
G SP Q+
Sbjct: 258 Q--AGLSPAEIQQL 269
Score = 38.5 bits (88), Expect = 0.13
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 30/83 (36%)
Query: 1713 KKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLF 1772
KK + + + QQQQQQQQQQQQQQQQQ Q+ QQQ Q Q
Sbjct: 140 KKQQEQLHLQLLQQQQQQQQQQQQQQQQQ----------------QQQQQQQQQQQQQ-- 181
Query: 1773 NPTLLPHFPMTTETLLQLQQQQH 1795
+ Q QQQQH
Sbjct: 182 ------------QQQQQQQQQQH 192
Score = 37.4 bits (85), Expect = 0.28
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 21/122 (17%)
Query: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNT 2466
LQL + ++ + + ++ + + Q Q Q++Q Q P Q +EQ +Q+
Sbjct: 148 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Query: 2467 PQQKLPQLVSLPSLPQ---------------------PPPQAPPPQCPLPQSSPSPSQLS 2505
Q QLV L Q PP QA P LPQ+ SP+++
Sbjct: 208 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ 267
Query: 2506 HL 2507
L
Sbjct: 268 QL 269
Score = 36.2 bits (82), Expect = 0.62
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG-APSPDKDPAKESPK 3420
QQ QQ Q + Q+ + QQQ Q+QQ QQQ+ + +PPG A P + +
Sbjct: 203 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262
Query: 3421 PEEQKNTPREVS 3432
P E + +EV+
Sbjct: 263 PAEIQQLWKEVT 274
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 65.9 bits (159), Expect = 7e-10
Identities = 48/123 (39%), Positives = 59/123 (47%), Gaps = 21/123 (17%)
Query: 1722 RQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFP 1781
+QQQQQQQQQQQQQQQQQQQ Q Q + QQ+ QQQ Q +F LL
Sbjct: 75 QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL---- 130
Query: 1782 MTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTL-----TGTGPGLLEDLK 1836
+ QLQQQQHLL Q +S+P AL + G P ++ L
Sbjct: 131 ----QMQQLQQQQHLL--------SLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLW 178
Query: 1837 AQV 1839
+V
Sbjct: 179 KEV 181
Score = 52.4 bits (124), Expect = 8e-06
Identities = 29/73 (39%), Positives = 44/73 (60%), Gaps = 11/73 (15%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
LLQQ QQ QQ Q+ QQQQQ+Q QQQQQQ+ QQQQ + Q + P K++
Sbjct: 58 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------QHPGKQAK 106
Query: 3420 KPEEQKNTPREVS 3432
+ ++Q+ ++++
Sbjct: 107 EQQQQQQQQQQLA 119
Score = 45.8 bits (107), Expect = 8e-04
Identities = 47/146 (32%), Positives = 53/146 (36%), Gaps = 63/146 (43%)
Query: 1723 QQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPM 1782
QQQQQQQQQQQQQQQQQQQ Q Q Q Q QQ+ QQQ
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQQQ------------------- 95
Query: 1783 TTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVP 1842
QQQQH G E + Q Q
Sbjct: 96 --------QQQQH-------------------------------PGKQAKEQQQQQQQQQ 116
Query: 1843 QQSHQQILPQQQQNQLSIAQSHSALL 1868
Q + QQ++ QQQ Q+ Q LL
Sbjct: 117 QLAAQQLVFQQQLLQMQQLQQQQHLL 142
Score = 41.6 bits (96), Expect = 0.015
Identities = 42/140 (30%), Positives = 59/140 (42%), Gaps = 34/140 (24%)
Query: 1761 QQQAALIQSQLFNPTLLPHFPMTTETLLQLQQ----QQHLLFPFYIPSAEFQLNPEVSLP 1816
QQ ++Q Q+ +P L + LLQ QQ QQ L FY E QL+ +
Sbjct: 10 QQMQQILQQQVLSPQQL-------QALLQQQQAVMLQQQQLQEFYKKQQE-QLHLQ---- 57
Query: 1817 VTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEK 1876
LL+ + Q Q QQ QQ QQQQ Q Q Q QHP K
Sbjct: 58 --------------LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK 103
Query: 1877 KNKLVIKEKEKESQRERDSA 1896
+ KE++++ Q+++ A
Sbjct: 104 Q----AKEQQQQQQQQQQLA 119
Score = 40.4 bits (93), Expect = 0.033
Identities = 23/42 (54%), Positives = 28/42 (66%), Gaps = 3/42 (7%)
Query: 3362 QQYQQYQQSLQEAIQQQQQ---RQLQQQQQQKVQQQQPKASQ 3400
QQ QQ QQ Q+ QQQQQ +Q ++QQQQ+ QQQQ A Q
Sbjct: 81 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 122
Score = 40.0 bits (92), Expect = 0.043
Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 19/134 (14%)
Query: 3193 QQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE 3252
QQ QQQQQQQQ Q QQ QQQQQ++ + ++ +++++ H GK
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQ--------------QQQQQQQQQQQQQQQQQQQQHPGKQA 105
Query: 3253 PLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQ-AALTSDP--TALLTSQFLP 3309
++++ + A L M+ L +LQ L S P A L Q LP
Sbjct: 106 KEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLP 165
Query: 3310 YFVPGFSPYYAPQI 3323
G SP Q+
Sbjct: 166 Q--AGLSPAEIQQL 177
Score = 38.5 bits (88), Expect = 0.13
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 30/83 (36%)
Query: 1713 KKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLF 1772
KK + + + QQQQQQQQQQQQQQQQQ Q+ QQQ Q Q
Sbjct: 48 KKQQEQLHLQLLQQQQQQQQQQQQQQQQQ----------------QQQQQQQQQQQQQ-- 89
Query: 1773 NPTLLPHFPMTTETLLQLQQQQH 1795
+ Q QQQQH
Sbjct: 90 ------------QQQQQQQQQQH 100
Score = 37.4 bits (85), Expect = 0.28
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 21/122 (17%)
Query: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNT 2466
LQL + ++ + + ++ + + Q Q Q++Q Q P Q +EQ +Q+
Sbjct: 56 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115
Query: 2467 PQQKLPQLVSLPSLPQ---------------------PPPQAPPPQCPLPQSSPSPSQLS 2505
Q QLV L Q PP QA P LPQ+ SP+++
Sbjct: 116 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ 175
Query: 2506 HL 2507
L
Sbjct: 176 QL 177
Score = 37.0 bits (84), Expect = 0.36
Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 10/161 (6%)
Query: 1707 PKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAAL 1766
P++ + +++ +Q Q QQQQ QQQQ + + Q Q+ L Q+ QQQ
Sbjct: 9 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ 68
Query: 1767 IQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTG 1826
Q Q + Q QQQQ P + E Q + + + L
Sbjct: 69 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-QAKEQQQQQQQQQQLAAQQLVFQ- 126
Query: 1827 TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSAL 1867
+ L Q+ QQ H +L Q+Q +SI +AL
Sbjct: 127 ------QQLLQMQQLQQQQH--LLSLQRQGLISIPPGQAAL 159
Score = 36.2 bits (82), Expect = 0.62
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG-APSPDKDPAKESPK 3420
QQ QQ Q + Q+ + QQQ Q+QQ QQQ+ + +PPG A P + +
Sbjct: 111 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 170
Query: 3421 PEEQKNTPREVS 3432
P E + +EV+
Sbjct: 171 PAEIQQLWKEVT 182
Score = 32.3 bits (72), Expect = 9.0
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 13/87 (14%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQK-------------VQQQQPKASQTPVPPG 3406
+LQQ Q LQ +QQQQ LQQQQ Q+ +QQQQ + Q
Sbjct: 15 ILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 74
Query: 3407 APSPDKDPAKESPKPEEQKNTPREVSP 3433
+ ++ + ++Q+ ++ P
Sbjct: 75 QQQQQQQQQQQQQQQQQQQQQQQQQHP 101
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 65.9 bits (159), Expect = 7e-10
Identities = 48/123 (39%), Positives = 59/123 (47%), Gaps = 21/123 (17%)
Query: 1722 RQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFP 1781
+QQQQQQQQQQQQQQQQQQQ Q Q + QQ+ QQQ Q +F LL
Sbjct: 192 QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL---- 247
Query: 1782 MTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTL-----TGTGPGLLEDLK 1836
+ QLQQQQHLL Q +S+P AL + G P ++ L
Sbjct: 248 ----QMQQLQQQQHLL--------SLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLW 295
Query: 1837 AQV 1839
+V
Sbjct: 296 KEV 298
Score = 52.4 bits (124), Expect = 8e-06
Identities = 29/73 (39%), Positives = 44/73 (60%), Gaps = 11/73 (15%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
LLQQ QQ QQ Q+ QQQQQ+Q QQQQQQ+ QQQQ + Q + P K++
Sbjct: 175 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------QHPGKQAK 223
Query: 3420 KPEEQKNTPREVS 3432
+ ++Q+ ++++
Sbjct: 224 EQQQQQQQQQQLA 236
Score = 45.8 bits (107), Expect = 8e-04
Identities = 47/146 (32%), Positives = 53/146 (36%), Gaps = 63/146 (43%)
Query: 1723 QQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPM 1782
QQQQQQQQQQQQQQQQQQQ Q Q Q Q QQ+ QQQ
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQQQ------------------- 212
Query: 1783 TTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVP 1842
QQQQH G E + Q Q
Sbjct: 213 --------QQQQH-------------------------------PGKQAKEQQQQQQQQQ 233
Query: 1843 QQSHQQILPQQQQNQLSIAQSHSALL 1868
Q + QQ++ QQQ Q+ Q LL
Sbjct: 234 QLAAQQLVFQQQLLQMQQLQQQQHLL 259
Score = 41.6 bits (96), Expect = 0.015
Identities = 42/140 (30%), Positives = 59/140 (42%), Gaps = 34/140 (24%)
Query: 1761 QQQAALIQSQLFNPTLLPHFPMTTETLLQLQQ----QQHLLFPFYIPSAEFQLNPEVSLP 1816
QQ ++Q Q+ +P L + LLQ QQ QQ L FY E QL+ +
Sbjct: 127 QQMQQILQQQVLSPQQL-------QALLQQQQAVMLQQQQLQEFYKKQQE-QLHLQ---- 174
Query: 1817 VTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEK 1876
LL+ + Q Q QQ QQ QQQQ Q Q Q QHP K
Sbjct: 175 --------------LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK 220
Query: 1877 KNKLVIKEKEKESQRERDSA 1896
+ KE++++ Q+++ A
Sbjct: 221 Q----AKEQQQQQQQQQQLA 236
Score = 40.4 bits (93), Expect = 0.033
Identities = 23/42 (54%), Positives = 28/42 (66%), Gaps = 3/42 (7%)
Query: 3362 QQYQQYQQSLQEAIQQQQQ---RQLQQQQQQKVQQQQPKASQ 3400
QQ QQ QQ Q+ QQQQQ +Q ++QQQQ+ QQQQ A Q
Sbjct: 198 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 239
Score = 40.0 bits (92), Expect = 0.043
Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 22/134 (16%)
Query: 3193 QQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE 3252
QQ QQQQQQQQ Q QQ QQQQQ++ + ++ +++++ H GK
Sbjct: 180 QQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQQQQQQQQQQQQHPGKQA 222
Query: 3253 PLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQ-AALTSDP--TALLTSQFLP 3309
++++ + A L M+ L +LQ L S P A L Q LP
Sbjct: 223 KEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLP 282
Query: 3310 YFVPGFSPYYAPQI 3323
G SP Q+
Sbjct: 283 Q--AGLSPAEIQQL 294
Score = 38.5 bits (88), Expect = 0.13
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 30/83 (36%)
Query: 1713 KKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLF 1772
KK + + + QQQQQQQQQQQQQQQQQ Q+ QQQ Q Q
Sbjct: 165 KKQQEQLHLQLLQQQQQQQQQQQQQQQQQ----------------QQQQQQQQQQQQQ-- 206
Query: 1773 NPTLLPHFPMTTETLLQLQQQQH 1795
+ Q QQQQH
Sbjct: 207 ------------QQQQQQQQQQH 217
Score = 37.7 bits (86), Expect = 0.21
Identities = 43/174 (24%), Positives = 68/174 (39%), Gaps = 12/174 (6%)
Query: 1696 PIGANIASPS--EPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753
P+ + +P P++ + +++ +Q Q QQQQ QQQQ + + Q Q+
Sbjct: 113 PVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLH 172
Query: 1754 AHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEV 1813
L Q+ QQQ Q Q + Q QQQQ P + E Q +
Sbjct: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-QAKEQQQQQQQ 231
Query: 1814 SLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSAL 1867
+ + L + L Q+ QQ H +L Q+Q +SI +AL
Sbjct: 232 QQQLAAQQLVFQ-------QQLLQMQQLQQQQH--LLSLQRQGLISIPPGQAAL 276
Score = 37.4 bits (85), Expect = 0.28
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 21/122 (17%)
Query: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNT 2466
LQL + ++ + + ++ + + Q Q Q++Q Q P Q +EQ +Q+
Sbjct: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
Query: 2467 PQQKLPQLVSLPSLPQ---------------------PPPQAPPPQCPLPQSSPSPSQLS 2505
Q QLV L Q PP QA P LPQ+ SP+++
Sbjct: 233 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ 292
Query: 2506 HL 2507
L
Sbjct: 293 QL 294
Score = 36.2 bits (82), Expect = 0.62
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPG-APSPDKDPAKESPK 3420
QQ QQ Q + Q+ + QQQ Q+QQ QQQ+ + +PPG A P + +
Sbjct: 228 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287
Query: 3421 PEEQKNTPREVS 3432
P E + +EV+
Sbjct: 288 PAEIQQLWKEVT 299
Score = 32.7 bits (73), Expect = 6.9
Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 18/181 (9%)
Query: 1725 QQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPH----- 1779
QQQQ Q +Q QQQ L ++ + QEL + L + PH
Sbjct: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAV 112
Query: 1780 ---FPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLK 1836
M T ++ QQ Q +L + L+P+ + + L E K
Sbjct: 113 PVSVAMMTPQVITPQQMQQIL-------QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK 165
Query: 1837 AQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSA 1896
Q +Q H Q+L QQQQ Q Q Q Q +++ + ++++++ Q A
Sbjct: 166 KQ---QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 222
Query: 1897 E 1897
+
Sbjct: 223 K 223
Score = 32.3 bits (72), Expect = 9.0
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 13/87 (14%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQK-------------VQQQQPKASQTPVPPG 3406
+LQQ Q LQ +QQQQ LQQQQ Q+ +QQQQ + Q
Sbjct: 132 ILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 191
Query: 3407 APSPDKDPAKESPKPEEQKNTPREVSP 3433
+ ++ + ++Q+ ++ P
Sbjct: 192 QQQQQQQQQQQQQQQQQQQQQQQQQHP 218
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo
sapiens]
Length = 898
Score = 65.5 bits (158), Expect = 1e-09
Identities = 84/323 (26%), Positives = 122/323 (37%), Gaps = 39/323 (12%)
Query: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184
PGL +PSL TP A PNL P T S G P G+P PS +LS P
Sbjct: 130 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
Query: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243
+ P ++ Q P + PP ++ P++ + Q + KEK
Sbjct: 183 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
Query: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302
P P+ E EA A + S+ PT + Q++A A + P
Sbjct: 243 R---------TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
Query: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357
T LP +P F P Q+ +QS QP QA SP
Sbjct: 294 QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-QTQPRIPSTDTQVQPKLQKQAQTQTSP 351
Query: 3358 GSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKE 3417
L+ Q +Q Q LQ+ + + Q+Q+Q Q Q + Q P+ Q + +P K+
Sbjct: 352 EHLVLQQKQVQPQLQQ--EAEPQKQVQPQVQPQAHSQGPRQVQL-------QQEAEPLKQ 402
Query: 3418 ---SPKPEEQKNTPREVSPLLPK 3437
+P+ PR+V L K
Sbjct: 403 VQPQVQPQAHSQPPRQVQLQLQK 425
Score = 63.9 bits (154), Expect = 3e-09
Identities = 112/462 (24%), Positives = 160/462 (34%), Gaps = 63/462 (13%)
Query: 1721 SRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQ------------------ 1762
S+QQQQQ QQQQQQ QQ QQQ Q Q Q LQQ LQQ
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
Query: 1763 --QAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSG 1820
Q L+ Q N L + M LL LQQ Q L F +P A + T G
Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALL-LQQLQG-LDQFAMPPATYDTAGLTMPTATLG 120
Query: 1821 ALTLTG-TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------H 1873
L G PGL Q+ + QQ PQ + L + PSQ +
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 1874 PEKK----NKLVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEK 1918
P+K+ + K+ SQ + D EG E P+ + LP + K
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 1919 KELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGE 1978
++ P EP A R + E G V + + V K+ D
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 1979 NLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP------- 2031
E LE + +L +++ + Q P + K + + P
Sbjct: 301 --EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
Query: 2032 --LRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPI--TSPTIAPAQPSVPLTQ 2087
++PQ + P P P A Q + A P+ P + P S P Q
Sbjct: 359 KQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
Query: 2088 LSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA 2129
+ + ++ + QT + Q P + P E PA ++
Sbjct: 419 VQLQLQKQV------QTQTYPQVHTQAQPSVQPQEHPPAQVS 454
Score = 47.4 bits (111), Expect = 3e-04
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)
Query: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040
C +C+ + + FQ H +H Q+ + H+ + + + + P
Sbjct: 595 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 654
Query: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100
CN C Y + L ++ Q H+ + +S C +CN K
Sbjct: 655 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 697
Query: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160
++HV+S H+ + ++L+ L+K + +DED C D EE ED E
Sbjct: 698 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 754
Query: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198
E + E + + S + + T SP T+ + F
Sbjct: 755 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 792
Score = 45.1 bits (105), Expect = 0.001
Identities = 47/179 (26%), Positives = 72/179 (40%), Gaps = 29/179 (16%)
Query: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQ--------QQQQQQQQQQQQQQAQTLAQA 1748
+ A + S ++P+ + +Q Q Q QQ+Q Q Q QQ+ + Q Q
Sbjct: 318 VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 377
Query: 1749 QAQVQAH----LQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPS 1804
Q Q QAH Q +LQQ+A ++ P + P +QLQ Q+ + Y P
Sbjct: 378 QVQPQAHSQGPRQVQLQQEAEPLKQ--VQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQ 434
Query: 1805 AEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQS 1863
Q P V P + VQ P+Q+H+Q Q Q + L+ Q+
Sbjct: 435 VHTQAQPSVQ--------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Score = 43.1 bits (100), Expect = 0.005
Identities = 24/49 (48%), Positives = 29/49 (59%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
Score = 42.0 bits (97), Expect = 0.011
Identities = 75/259 (28%), Positives = 101/259 (38%), Gaps = 70/259 (27%)
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496
S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
Query: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN--------------------LPP----------- 2525
S P Q PL L + L N +PP
Sbjct: 56 SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMP 115
Query: 2526 -----QLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDP 2579
L Y LA PS Q L+ N Q PQ +SL P + P
Sbjct: 116 TATLGNLRGYGMASPGLAAPSLTPPQ-------LATPNLQQFFPQATRQSLLGPPPVGVP 168
Query: 2580 SNPLLASQL-LSGAIPQIPA--SSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGE 2636
NP SQ LSG PQ A SS+T+P+ S+ T+ +E+K+ G ++
Sbjct: 169 MNP---SQFNLSGRNPQKQARTSSSTTPNRKDSSSQTM--PVEDKSDPPEGSEEAA---- 219
Query: 2637 EPQRDKRLRTTITPEQLEI 2655
EP+ D TPE ++
Sbjct: 220 EPRMD-------TPEDQDL 231
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/55 (40%), Positives = 30/55 (54%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414
L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P
Sbjct: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Score = 40.4 bits (93), Expect = 0.033
Identities = 65/286 (22%), Positives = 104/286 (36%), Gaps = 47/286 (16%)
Query: 1668 PSSAGIAPSSNLLS-QVPTESVGMPPLGNPIGANI-ASPSEPKEANRKKL------ADMI 1719
P A P+ L S + PTE PP + A A + PK+ L A ++
Sbjct: 251 PCEASELPAKRLRSSEEPTEKE--PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
Query: 1720 ASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPH 1779
Q + Q Q Q Q Q Q + T Q Q ++Q Q + + ++Q + P L
Sbjct: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 368
Query: 1780 FPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQV 1839
+ Q+Q Q H P + + Q E V + P L+ Q
Sbjct: 369 AEPQKQVQPQVQPQAHSQGPRQV---QLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQK 425
Query: 1840 QVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGG 1899
QV Q++ Q+ Q Q + +QP +HP + + + E E+ +
Sbjct: 426 QVQTQTYPQVHTQAQPS-----------VQPQEHPPAQ----VSVQPPEQTHEQPHTQPQ 470
Query: 1900 EGNTGPKET-----------LPDALKAKEKKELAPGGGSEPSMLPP 1934
P++T PDA++A GGG E ++ P
Sbjct: 471 VSLLAPEQTPVVVHVCGLEMPPDAVEA--------GGGMEKTLPEP 508
Score = 39.3 bits (90), Expect = 0.073
Identities = 58/270 (21%), Positives = 96/270 (35%), Gaps = 27/270 (10%)
Query: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE- 3252
Q QQQ QQQQ Q+Q QL QQ QQ++ + + ++ ++ + +
Sbjct: 4 QQQQQQLQQQQQQLQ--------------QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA 49
Query: 3253 PLP------VPKKEKGEAPTATAATISAPL---PTMEYAVDPAQLQALQAALTSDPTALL 3303
PLP +P ++ + T SA L ++ A+ QLQ L T
Sbjct: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
Query: 3304 TSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQ 3362
+P G Y PG P L + P A Q+L+G P +
Sbjct: 110 AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169
Query: 3363 QYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPE 3422
Q+ S + +Q + ++ Q PP +P ++P+ +
Sbjct: 170 NPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 229
Query: 3423 EQKNTPREVSPLLPKLPEEPEAESKSADSL 3452
+ P +++ K PE E A L
Sbjct: 230 DLPPCPEDIAK--EKRTPAPEPEPCEASEL 257
Score = 37.0 bits (84), Expect = 0.36
Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%)
Query: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482
+G K A S+ ++ Q P + + PE ++ P+ P+ LP P
Sbjct: 177 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 234
Query: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542
P A + P P+ P P + S LP K L +S P QL Q ++ P
Sbjct: 235 PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 290
Query: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601
Q P L +L+ + F P + +Q+ S P+I
Sbjct: 291 ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 330
Query: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623
PST T L+++ + + S
Sbjct: 331 --PSTDTQVQPKLQKQAQTQTS 350
Score = 33.9 bits (76), Expect = 3.1
Identities = 56/236 (23%), Positives = 85/236 (36%), Gaps = 37/236 (15%)
Query: 2351 CYKDEDEEGQDDSQNEDSMDAMEILTPTSSSCSTPM----PSQAYSAPAPSAN-----NT 2401
C +D +E + + + +A E+ S P P Q P A T
Sbjct: 234 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
Query: 2402 ASSAFLQLTAEAEELATFNSKT---EAGDEKPKLAEAPSA----QPNQTQEKQGQPKPE- 2453
+ L EA+ L F + +A + PS QP ++ Q Q PE
Sbjct: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
Query: 2454 ---LQQQEQPE-QKTNTPQQKL------------PQLVSLPSLPQPPPQAPPPQCPLPQS 2497
Q+Q QP+ Q+ PQ+++ P+ V L +P Q P P S
Sbjct: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHS 413
Query: 2498 SPSPSQLSHLPLKPLHTST-PQQLANLPPQLIPYQCDQCKLAF--PSFEHWQEHQQ 2550
P P Q+ K + T T PQ P + P + +++ P H Q H Q
Sbjct: 414 QP-PRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
Score = 33.5 bits (75), Expect = 4.0
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
E + EEEE++E+EEE E E+E CK + ++ E
Sbjct: 741 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 774
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo
sapiens]
Length = 898
Score = 65.5 bits (158), Expect = 1e-09
Identities = 84/323 (26%), Positives = 122/323 (37%), Gaps = 39/323 (12%)
Query: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184
PGL +PSL TP A PNL P T S G P G+P PS +LS P
Sbjct: 130 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
Query: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243
+ P ++ Q P + PP ++ P++ + Q + KEK
Sbjct: 183 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
Query: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302
P P+ E EA A + S+ PT + Q++A A + P
Sbjct: 243 R---------TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
Query: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357
T LP +P F P Q+ +QS QP QA SP
Sbjct: 294 QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-QTQPRIPSTDTQVQPKLQKQAQTQTSP 351
Query: 3358 GSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKE 3417
L+ Q +Q Q LQ+ + + Q+Q+Q Q Q + Q P+ Q + +P K+
Sbjct: 352 EHLVLQQKQVQPQLQQ--EAEPQKQVQPQVQPQAHSQGPRQVQL-------QQEAEPLKQ 402
Query: 3418 ---SPKPEEQKNTPREVSPLLPK 3437
+P+ PR+V L K
Sbjct: 403 VQPQVQPQAHSQPPRQVQLQLQK 425
Score = 63.9 bits (154), Expect = 3e-09
Identities = 112/462 (24%), Positives = 160/462 (34%), Gaps = 63/462 (13%)
Query: 1721 SRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQ------------------ 1762
S+QQQQQ QQQQQQ QQ QQQ Q Q Q LQQ LQQ
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
Query: 1763 --QAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSG 1820
Q L+ Q N L + M LL LQQ Q L F +P A + T G
Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALL-LQQLQG-LDQFAMPPATYDTAGLTMPTATLG 120
Query: 1821 ALTLTG-TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------H 1873
L G PGL Q+ + QQ PQ + L + PSQ +
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 1874 PEKK----NKLVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEK 1918
P+K+ + K+ SQ + D EG E P+ + LP + K
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 1919 KELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGE 1978
++ P EP A R + E G V + + V K+ D
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 1979 NLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP------- 2031
E LE + +L +++ + Q P + K + + P
Sbjct: 301 --EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
Query: 2032 --LRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPI--TSPTIAPAQPSVPLTQ 2087
++PQ + P P P A Q + A P+ P + P S P Q
Sbjct: 359 KQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
Query: 2088 LSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA 2129
+ + ++ + QT + Q P + P E PA ++
Sbjct: 419 VQLQLQKQV------QTQTYPQVHTQAQPSVQPQEHPPAQVS 454
Score = 47.4 bits (111), Expect = 3e-04
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)
Query: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040
C +C+ + + FQ H +H Q+ + H+ + + + + P
Sbjct: 595 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 654
Query: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100
CN C Y + L ++ Q H+ + +S C +CN K
Sbjct: 655 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 697
Query: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160
++HV+S H+ + ++L+ L+K + +DED C D EE ED E
Sbjct: 698 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 754
Query: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198
E + E + + S + + T SP T+ + F
Sbjct: 755 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 792
Score = 45.1 bits (105), Expect = 0.001
Identities = 47/179 (26%), Positives = 72/179 (40%), Gaps = 29/179 (16%)
Query: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQ--------QQQQQQQQQQQQQQAQTLAQA 1748
+ A + S ++P+ + +Q Q Q QQ+Q Q Q QQ+ + Q Q
Sbjct: 318 VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 377
Query: 1749 QAQVQAH----LQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPS 1804
Q Q QAH Q +LQQ+A ++ P + P +QLQ Q+ + Y P
Sbjct: 378 QVQPQAHSQGPRQVQLQQEAEPLKQ--VQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQ 434
Query: 1805 AEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQS 1863
Q P V P + VQ P+Q+H+Q Q Q + L+ Q+
Sbjct: 435 VHTQAQPSVQ--------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Score = 43.1 bits (100), Expect = 0.005
Identities = 24/49 (48%), Positives = 29/49 (59%)
Query: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
Score = 42.0 bits (97), Expect = 0.011
Identities = 75/259 (28%), Positives = 101/259 (38%), Gaps = 70/259 (27%)
Query: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496
S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+
Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
Query: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN--------------------LPP----------- 2525
S P Q PL L + L N +PP
Sbjct: 56 SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMP 115
Query: 2526 -----QLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDP 2579
L Y LA PS Q L+ N Q PQ +SL P + P
Sbjct: 116 TATLGNLRGYGMASPGLAAPSLTPPQ-------LATPNLQQFFPQATRQSLLGPPPVGVP 168
Query: 2580 SNPLLASQL-LSGAIPQIPA--SSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGE 2636
NP SQ LSG PQ A SS+T+P+ S+ T+ +E+K+ G ++
Sbjct: 169 MNP---SQFNLSGRNPQKQARTSSSTTPNRKDSSSQTM--PVEDKSDPPEGSEEAA---- 219
Query: 2637 EPQRDKRLRTTITPEQLEI 2655
EP+ D TPE ++
Sbjct: 220 EPRMD-------TPEDQDL 231
Score = 40.4 bits (93), Expect = 0.033
Identities = 22/55 (40%), Positives = 30/55 (54%)
Query: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414
L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P
Sbjct: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Score = 40.4 bits (93), Expect = 0.033
Identities = 65/286 (22%), Positives = 104/286 (36%), Gaps = 47/286 (16%)
Query: 1668 PSSAGIAPSSNLLS-QVPTESVGMPPLGNPIGANI-ASPSEPKEANRKKL------ADMI 1719
P A P+ L S + PTE PP + A A + PK+ L A ++
Sbjct: 251 PCEASELPAKRLRSSEEPTEKE--PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
Query: 1720 ASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPH 1779
Q + Q Q Q Q Q Q + T Q Q ++Q Q + + ++Q + P L
Sbjct: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 368
Query: 1780 FPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQV 1839
+ Q+Q Q H P + + Q E V + P L+ Q
Sbjct: 369 AEPQKQVQPQVQPQAHSQGPRQV---QLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQK 425
Query: 1840 QVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGG 1899
QV Q++ Q+ Q Q + +QP +HP + + + E E+ +
Sbjct: 426 QVQTQTYPQVHTQAQPS-----------VQPQEHPPAQ----VSVQPPEQTHEQPHTQPQ 470
Query: 1900 EGNTGPKET-----------LPDALKAKEKKELAPGGGSEPSMLPP 1934
P++T PDA++A GGG E ++ P
Sbjct: 471 VSLLAPEQTPVVVHVCGLEMPPDAVEA--------GGGMEKTLPEP 508
Score = 39.3 bits (90), Expect = 0.073
Identities = 58/270 (21%), Positives = 96/270 (35%), Gaps = 27/270 (10%)
Query: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE- 3252
Q QQQ QQQQ Q+Q QL QQ QQ++ + + ++ ++ + +
Sbjct: 4 QQQQQQLQQQQQQLQ--------------QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA 49
Query: 3253 PLP------VPKKEKGEAPTATAATISAPL---PTMEYAVDPAQLQALQAALTSDPTALL 3303
PLP +P ++ + T SA L ++ A+ QLQ L T
Sbjct: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
Query: 3304 TSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQ 3362
+P G Y PG P L + P A Q+L+G P +
Sbjct: 110 AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169
Query: 3363 QYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPE 3422
Q+ S + +Q + ++ Q PP +P ++P+ +
Sbjct: 170 NPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 229
Query: 3423 EQKNTPREVSPLLPKLPEEPEAESKSADSL 3452
+ P +++ K PE E A L
Sbjct: 230 DLPPCPEDIAK--EKRTPAPEPEPCEASEL 257
Score = 37.0 bits (84), Expect = 0.36
Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%)
Query: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482
+G K A S+ ++ Q P + + PE ++ P+ P+ LP P
Sbjct: 177 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 234
Query: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542
P A + P P+ P P + S LP K L +S P QL Q ++ P
Sbjct: 235 PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 290
Query: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601
Q P L +L+ + F P + +Q+ S P+I
Sbjct: 291 ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 330
Query: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623
PST T L+++ + + S
Sbjct: 331 --PSTDTQVQPKLQKQAQTQTS 350
Score = 33.9 bits (76), Expect = 3.1
Identities = 56/236 (23%), Positives = 85/236 (36%), Gaps = 37/236 (15%)
Query: 2351 CYKDEDEEGQDDSQNEDSMDAMEILTPTSSSCSTPM----PSQAYSAPAPSAN-----NT 2401
C +D +E + + + +A E+ S P P Q P A T
Sbjct: 234 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
Query: 2402 ASSAFLQLTAEAEELATFNSKT---EAGDEKPKLAEAPSA----QPNQTQEKQGQPKPE- 2453
+ L EA+ L F + +A + PS QP ++ Q Q PE
Sbjct: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
Query: 2454 ---LQQQEQPE-QKTNTPQQKL------------PQLVSLPSLPQPPPQAPPPQCPLPQS 2497
Q+Q QP+ Q+ PQ+++ P+ V L +P Q P P S
Sbjct: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHS 413
Query: 2498 SPSPSQLSHLPLKPLHTST-PQQLANLPPQLIPYQCDQCKLAF--PSFEHWQEHQQ 2550
P P Q+ K + T T PQ P + P + +++ P H Q H Q
Sbjct: 414 QP-PRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
Score = 33.5 bits (75), Expect = 4.0
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
E + EEEE++E+EEE E E+E CK + ++ E
Sbjct: 741 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 774
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 173,596,726
Number of Sequences: 37866
Number of extensions: 10482098
Number of successful extensions: 329667
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2793
Number of HSP's successfully gapped in prelim test: 1873
Number of HSP's that attempted gapping in prelim test: 84810
Number of HSP's gapped (non-prelim): 151341
length of query: 3703
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3581
effective length of database: 13,627,866
effective search space: 48801388146
effective search space used: 48801388146
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.