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Search of human proteins with 239751637
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
(1124 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 2278 0.0
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 972 0.0
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 959 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 284 4e-76
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 212 1e-54
gi|116284392 mucin 2 precursor [Homo sapiens] 196 8e-50
gi|160707881 formin 2 [Homo sapiens] 182 1e-45
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 173 9e-43
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 172 1e-42
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 169 1e-41
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 169 1e-41
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 169 1e-41
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 169 1e-41
gi|47132519 Ras association and pleckstrin homology domains 1 is... 169 1e-41
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 164 6e-40
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 162 2e-39
gi|55750053 atrophin-1 [Homo sapiens] 155 3e-37
gi|55750041 atrophin-1 [Homo sapiens] 155 3e-37
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 154 6e-37
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 154 6e-37
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 154 6e-37
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 154 6e-37
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 154 6e-37
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 154 6e-37
gi|112421108 capicua homolog [Homo sapiens] 154 6e-37
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 152 1e-36
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 152 2e-36
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 150 5e-36
gi|150170670 piccolo isoform 2 [Homo sapiens] 149 2e-35
gi|150378539 piccolo isoform 1 [Homo sapiens] 149 2e-35
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 2278 bits (5902), Expect = 0.0
Identities = 1124/1124 (100%), Positives = 1124/1124 (100%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Query: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
Query: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
Query: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
PPLQGLPSPPLSPLATPPPQAPP LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Query: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
Query: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840
LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840
Query: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900
QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900
Query: 901 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960
SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW
Sbjct: 901 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960
Query: 961 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 1020
PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA
Sbjct: 961 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 1020
Query: 1021 RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAEL 1080
RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAEL
Sbjct: 1021 RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAEL 1080
Query: 1081 GRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 1124
GRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH
Sbjct: 1081 GRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 1124
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 972 bits (2512), Expect = 0.0
Identities = 559/897 (62%), Positives = 605/897 (67%), Gaps = 74/897 (8%)
Query: 253 ARSGPSARGTPRA-------PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
A++G +AR TP A P P P+P PP VTP A G + PLA
Sbjct: 8 AKAGAAAR-TPAARAPGLLTPRPPGSPRP-------PPPVTPAALRVLGAAGAVGRKPLA 59
Query: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365
+ G +P A P + S A+ P + APP+ T P P ++P
Sbjct: 60 ERA-GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP- 117
Query: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
S TT P P Q I ++ P ALS+ A PT
Sbjct: 118 --GRASGTTRP---GPLGQKGLRISAEETVARGKATEAPKRSALSA-GARRDTSGPTPGT 171
Query: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ R + P RPA + PP + P +S ++ P+ + P
Sbjct: 172 PSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL--PSLAP 543
LQ +S + S PLSS P S+ P P+ L+ L P + P
Sbjct: 231 GGGLQRPASRSLSSSATPLSS---PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 544 PPLQTASA--PLTTPHLETPPCPAPCPLQAPPS-PLTTPPPETPSSIATPPPQAPPALAS 600
P A A PL++ L TP A QAPP+ P T +ATP P APP+ ++
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
Query: 601 PP-LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
PP LQ LPSPP ATPP QA L P LQA S SPPLSPLATP PQAP ALA+
Sbjct: 348 PPSLQTLPSPP----ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL- 402
Query: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA------------APPLQVP 707
PP+QAP SPPASPP+SP ATP QAP +LA +PP+Q P
Sbjct: 403 -----------PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
Query: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767
SPPASPP+SPSATPP QAPP LAAPPLQVPPSPPASPPMSPSATPPP+ PP LAAPPLQ
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511
Query: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827
LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP
Sbjct: 512 -------------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 888 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 947
PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP
Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 678
Query: 948 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAG 1007
LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAG
Sbjct: 679 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAG 738
Query: 1008 AGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGV 1067
AGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGV
Sbjct: 739 AGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGV 798
Query: 1068 TGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 1124
TGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH
Sbjct: 799 TGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 855
Score = 841 bits (2173), Expect = 0.0
Identities = 491/773 (63%), Positives = 525/773 (67%), Gaps = 85/773 (10%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
SSPLATPSPS + PP ATP ++L + LATPLPLAPPSPSAPPSLQTLPSP
Sbjct: 301 SSPLATPSPSAA-LQSQAPPTLPATPHSSSL--TCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 361 PATPPSQAPPSMTTPPMQA--------PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412
PATPPSQA S+ +P +QA P S PP Q P +L P LQAPPSP A L
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417
Query: 413 Q--ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ 470
AT S +P A H L +P +PP SPP+QAP S PASPP+
Sbjct: 418 SPLATPSPQAPNALAVH--LLQAP--------------FSPPPSPPVQAPFSPPASPPVS 461
Query: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPPSLQTPP 527
S +P P QA SLA+ Q P S PP+ T APP L PP
Sbjct: 462 PSATP------------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
L PP + P+LA PPLQ +P PA P QAP SP + P S +
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSP-----------PASFPGQAPFSPSASLP---MSPL 555
Query: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP----------PXLALPPLQAPPSPP 637
ATPPPQAPP LA+P LQ PSPP SP P + P P L L PP PP
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615
Query: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS---PSATPPSQ 694
+ P S L+ P ++ A + P A SPP ++ P+A
Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675
Query: 695 APP-SLAAPPLQVPPSPPASPPMS-------------PSATPPPQAPPPLAAP 733
APP + P P PPA+ P S SATP P A P +P
Sbjct: 676 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 959 bits (2480), Expect = 0.0
Identities = 556/899 (61%), Positives = 599/899 (66%), Gaps = 117/899 (13%)
Query: 253 ARSGPSARGTPRA-------PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
A++G +AR TP A P P P+P PP VTP A G + PLA
Sbjct: 8 AKAGAAAR-TPAARAPGLLTPRPPGSPRP-------PPPVTPAALRVLGAAGAVGRKPLA 59
Query: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS-----APPSLQTLPSP 360
+ A AT+P S P A P + P S APP+ T P P
Sbjct: 60 ---------------ERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGP 104
Query: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
++P S TT P P Q I ++ P ALS+ A
Sbjct: 105 VSSP---GRASGTTRP---GPLGQKGLRISAEETVARGKATEAPKRSALSA-GARRDTSG 157
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
PT + R + P RPA + PP + P +S ++ P+ +
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216
Query: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP--PASLTTPPLENL 538
P LQ +S + S PLSS + P + TP PA + P + L
Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSS--------PARSGPSARGTPRAPAHPSQPKPKGL 268
Query: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598
+L PP + TPP P P S S +ATP P APP+
Sbjct: 269 QALRPPQV-------------TPPRKDAAPALGPLSS---------SPLATPSPSAPPSP 306
Query: 599 ASPP-LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
++PP LQ LPSPP ATPP QA L P LQA S SPPLSPLATP PQAP ALA
Sbjct: 307 SAPPSLQTLPSPP----ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA------------APPLQ 705
+ PP+QAP SPPASPP+SP ATP QAP +LA +PP+Q
Sbjct: 363 L------------PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
P SPPASPP+SPSATPP QAPP LAAPPLQVPPSPPASPPMSPSATPPP+ PP LAAPP
Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
LQ LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA
Sbjct: 471 LQ-------------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577
Query: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 945
RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 637
Query: 946 PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 1005
PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA
Sbjct: 638 PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 697
Query: 1006 AGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 1065
AGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG
Sbjct: 698 AGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 757
Query: 1066 GVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 1124
GVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH
Sbjct: 758 GVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 816
Score = 773 bits (1997), Expect = 0.0
Identities = 465/770 (60%), Positives = 496/770 (64%), Gaps = 118/770 (15%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
RAGGIGGATIPESAPRAGPTR+ SRPPASGRGERAPPAKNTSPGPVSSPGRA
Sbjct: 61 RAGGIGGATIPESAPRAGPTRT---------SRPPASGRGERAPPAKNTSPGPVSSPGRA 111
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS
Sbjct: 112 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 171
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR
Sbjct: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291
Query: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT---L 357
SSPLATPSPS PP +A P TL PSPP ATP A S +P T L
Sbjct: 292 SSPLATPSPSA-------PPSPSAPPSLQTL-PSPP-ATPPSQATTSLGSPTLQATHSFL 342
Query: 358 PSPP----ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
PSPP ATPP QAPP++ PP+QAPPS PP+ SPLA S Q
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL---------------SPLATPSPQ 387
Query: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
A +L LQA S PP SPP+QAP S PASPP+ S
Sbjct: 388 APNALAVHLLQAPFS----------------------PPPSPPVQAPFSPPASPPVSPSA 425
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPPSLQTPPASL 530
+P P QA SLA+ Q P S PP+ T APP L PP L
Sbjct: 426 TP------------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
PP + P+LA PPLQ +P PA P QAP SP + P S +ATP
Sbjct: 474 AKPPPQAPPALATPPLQALPSP-----------PASFPGQAPFSPSASLP---MSPLATP 519
Query: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAP----------PXLALPPLQAPPSPPASP 640
PPQAPP LA+P LQ PSPP SP P + P P L L PP PP+
Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579
Query: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS---PSATPPSQAPP 697
P S L+ P ++ A + P A SPP ++ P+A APP
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 639
Query: 698 -SLAAPPLQVPPSPPASPPMS-------------PSATPPPQAPPPLAAP 733
+ P P PPA+ P S SATP P A P +P
Sbjct: 640 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 284 bits (726), Expect = 4e-76
Identities = 324/1146 (28%), Positives = 446/1146 (38%), Gaps = 210/1146 (18%)
Query: 8 AKAGAAARTPAARAPGLLTPRPPGSPR-------PPPPVTPAAL---RVLGAAGAVGRKP 57
A+AG + P L+ P SP P P++P A + LG +G KP
Sbjct: 547 AQAGLTTKKDPTVLP-LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIG-KP 604
Query: 58 LAERAGGIG---GATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAPPAKNTSPGP 113
+ +G A++ ++ AGP SAG ++ P + E A PA P
Sbjct: 605 ASSMTSPLGVNSSASVIKTDSYAGPD-SAGPLLKSSLITPTVAAFPLESADPA---GVAP 660
Query: 114 VSSPGRASGTTRPGPLGQKGLRISAEE-TVARGKATEAPKRSALS-----AGARRDTSGP 167
++ G ++ TT P + + ++ + V G T P S A + ++T P
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
Query: 168 TP----------GTPSPAMARRSRAAGTE-------VGLPRPAPSARPRPPTEGPRKSVS 210
PSP++ GT+ P S+ PTE S +
Sbjct: 721 LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT 780
Query: 211 SASEHSTT-----------EPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSP----- 252
++S+ + T SP +R P+ G G P +LSS +P+ +
Sbjct: 781 ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG-NLSSPVSPVEASFLPEN 839
Query: 253 ------ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-------------- 292
++ P+ +P P+ P P + L P VT P K+
Sbjct: 840 SLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 293 --------APALGPLSSSPL---ATPSPSGTKARPVPPPDNAATPLPATLPPSPP--LAT 339
APAL SSSP ATP+P G A P P A TP PA PPSP AT
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASP--SPKGAPTP-PAATPPSPKGGPAT 956
Query: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399
P P P+P A T PSP P + +P TPP PPS + P P +P
Sbjct: 957 PSPKWAPTPPAA----TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
Query: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
PPSP + S AT SP T +P+ PA+T P +
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP------S 1066
Query: 460 PLSLPASPPLQTSLSPAV----SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE-- 513
P PA+P L+ + +P SP P T P A A+ +P +P L PP +
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA-TPPSPKGGLATPPHKGA 1125
Query: 514 -TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC-PLQA 571
T + PPS P L TPP + P+ + L TP PP AP P
Sbjct: 1126 PTTPAATPPS---PKGGLATPPPKGAPTTPAATPPSPKGGLATP----PPKGAPTTPAAT 1178
Query: 572 PPSP---LTTPPPE-TPSSIATPPPQAPPALASPPLQGLPSPPLSP-------LATPPPQ 620
PPSP L TP P+ P++ A PP LA+P +G P+ P + LATP P+
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 621 APPXLALPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
P P PPSP PA+PP TP P +L L P P+P V P
Sbjct: 1239 GAP---TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295
Query: 678 SPPASPPVSP---SATPPSQAPP----SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
SP P SP + TPP+ PP S PP + P+PPA P SP TP A P
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 731 A-----APPLQVPPSPPASPPM---SPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPL 781
+ P + P+PPA+ P P+ TPP P+ P + +P + P+ PA +P+SP
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP--KGDPTSPAVIPLSPK 1413
Query: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA---P 838
P A P + +PPA P +P+ S P ATP + P L A P
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
Query: 839 LLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPRLTLALAPGP---PPPPSRSPSSTLSG 894
+ PP+P T +P++ P TP P + P L + P P PS
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAP---MGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
Query: 895 PDLAGHSSSATSTPEEL--------------------RGYDSGPEGGAAASPPPDAELAA 934
L + AT P+E + + P A+SPP A
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP------A 1584
Query: 935 CHPAAWSRGPAP-----PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989
P+ + P+P P A P PPA P S + +GP ATPAP
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE--------KGP--ATPAPK 1634
Query: 990 ALDPGP 995
P
Sbjct: 1635 GTPTSP 1640
Score = 262 bits (670), Expect = 1e-69
Identities = 293/1027 (28%), Positives = 393/1027 (38%), Gaps = 154/1027 (14%)
Query: 26 TPRPPGSPRPPPPV---TPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-----APRA 77
+P SP PP P TP+A+ L G V P + P+ AP+
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKG-VTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQKGLR 135
P S +SS A PA +G A P+ +P P ++ P G P P
Sbjct: 908 APALSMTSSSPKKARATPAP-KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA------GTEVGL 189
+ + G AT +PK + A + P TPSP A A G+
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P P ++ P T K +A+ P+ A PS GG PA+ SL + TP
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGAPTP- 1082
Query: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-----VTPPRKDA--APALGPLS-S 301
PA + PS +G P P+ P P A PP TPP K A PA P S
Sbjct: 1083 --PAATPPSPKGGPATPSPKGAPMPP---AATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Query: 302 SPLATPSPSGTKARPV------------PPPDNAATPLPATLPPSPP--LATPLP----- 342
LATP P G P PPP A T PA PPSP LATP P
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLATPSPKGAPT 1196
Query: 343 ---LAPPSPS---APPSLQTLPSPPA-TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
PPSP A PS + P+ PA TPPS T P AP + PP
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256
Query: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
T P AP P A P A + + P TSP + A TPP +
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL-IMPPLET 514
P +P P +PP + + +P SP L A + + P P S PP T
Sbjct: 1317 P-PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 515 QSSLAPPSLQTPPASLTTPPLEN------LPSLAP-PPLQTASAPLTTPHLETPPC---- 563
S P++ TPP+ P + + P++ P P + + P+T TP
Sbjct: 1376 PSHKGGPAM-TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434
Query: 564 -PAPCPLQAPPSPLTTPP---PETPSSIATP--PPQAPPALASPPLQ---GLPSPPLSPL 614
PA P+ +P T+ P P TPSS P P PP+ PP S P
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASP-----PLSPLAT------PSPQAPNALAVHLLQA 663
ATP P P L +P PA+P P++P AT P+ AP +
Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554
Query: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPPSPPASPPMSPS 719
SP +P + P PA+P +++PP+ P + P L +PP+ SP +
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV-TSPSPKEA 1613
Query: 720 ATPPPQAPP-PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778
TPP PP P P P P SPP++PS+ L+ P+ PAS+
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS--------------LKDSPTSPASVTC 1659
Query: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 838
+ PQA L P + L P P++ P++ AP
Sbjct: 1660 K-MGATVPQASKGL-------------------PAKKGPTALKEVLVAPAPESTPIITAP 1699
Query: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898
+ P + +S T +P P P GP T +AP P P + S T G D A
Sbjct: 1700 TRKGPQTKKSSAT--SPPICPDPSAKNGSKGPLST--VAPAPLLPVQKDSSKTAKGKD-A 1754
Query: 899 GHSSSATSTPEELRGYDSGPEGGAA---ASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 955
HS P E + S P AA P P++ A+ S P+PP++ AP
Sbjct: 1755 SHSPKGPLAPPESKA--STPLTAAAFEKVLPKPES-------ASVSAAPSPPVSLPLAP- 1804
Query: 956 APLPWPP 962
+P+P P
Sbjct: 1805 SPVPTLP 1811
Score = 251 bits (640), Expect = 4e-66
Identities = 296/1030 (28%), Positives = 402/1030 (39%), Gaps = 199/1030 (19%)
Query: 77 AGPTRS--AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
A PT + T P S P S +P A +P P TT L
Sbjct: 451 AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATT---------L 501
Query: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194
RI + + + S L + P + A ++A T P P
Sbjct: 502 RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561
Query: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS-----SSATPL 249
+ P +S SS+ E + + A++ + +PAS S SSA+ +
Sbjct: 562 LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVI 621
Query: 250 SSPARSGPSARG--------TPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPAL-GPL 299
+ + +GP + G TP A P + P G+ + A+P L G +
Sbjct: 622 KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
Query: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
S +P P GT TLP P + P+AP + L TL
Sbjct: 682 SLAPKNHPVKEGTLT---------------TLPLVPTASENCPVAPSPQNTCAPLATLVL 726
Query: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
P P S PS+ PP PP + + I +L + P S AT S
Sbjct: 727 APEIPKSVPSPSL--PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS- 783
Query: 420 SPTLQATHSFLTMSPRQTQASLTS-----PSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
+ T ++L SP S++ P++ S PD+P LS P SP ++ S
Sbjct: 784 ----KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI--GNLSSPVSP-VEASFL 836
Query: 475 PAVS-----PLSSPLTIHPLQALSSLASHSPQ-APLSSLIMPPLETQSSLAPPSLQTPPA 528
P S SP T H S SP+ AP S + P L+P + PP
Sbjct: 837 PENSLSFQGSKDSPATTH------SPTPPSPKGAPTPSAVTP-------LSPKGVTLPPK 883
Query: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588
TP + NLP P P P QAP +T+ P+ + A
Sbjct: 884 ETPTPSVVNLPFPKEGPA------------------TPAPKQAPALSMTSSSPK--KARA 923
Query: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPP-PQAPPXLALPPLQAPPSPPASPPLSPL-- 645
TP P+ PA SP +G P+PP ATPP P+ P A P + P+PPA+ P SP
Sbjct: 924 TPAPKGIPASPSP--KGAPTPPA---ATPPSPKGGP--ATPSPKWAPTPPAATPPSPKGG 976
Query: 646 -ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPP 703
ATPSP+ +P P +P + +PPA P SP +P + P + PP
Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036
Query: 704 LQVPPSPPASP---------PMSPSAT-PPPQAPPPLAAPPLQVPPSPPASPPMSPS--- 750
PPSP SP P +P+AT P P+ P A P L+ P+PPA+ P SP
Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP--ATPSLKGAPTPPAATPPSPKGGP 1094
Query: 751 ATPPPRVPPL------------LAAPPLQVPPSPPASLPMSP---LAKPPPQAPP----- 790
ATP P+ P+ LA PP + P+ PA+ P SP LA PPP+ P
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
Query: 791 -------ALATPPLQALPSPPASFPGQ------------APFSPSASLPMSP---LATPP 828
LATPP + P+ PA+ P AP +P+A+ P SP LATP
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPS 1213
Query: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--GPPPPPSR 886
P+ P A PPSP +P+ PT P + P+ A P G P PP+
Sbjct: 1214 PKGAPTTPA---ATPPSPKGGLATPSPKGAPTT-PAATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 887 SPSSTLSG---PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
+P S G P G + A TP P+GG A SPP A PAA
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTP-------PSPKGGPATSPPKGAPTP---PAATPPS 1319
Query: 944 PAPPLAFRGAPGAP----LPWPPATGPGSADGLCTIYETE-----GPESATPAPGALDPG 994
P +G+PG P P PPA P S G T+ T GP + + G P
Sbjct: 1320 P------KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 995 PSPGTSGGKA 1004
+P GG A
Sbjct: 1374 ATPSHKGGPA 1383
Score = 146 bits (369), Expect = 9e-35
Identities = 246/974 (25%), Positives = 353/974 (36%), Gaps = 167/974 (17%)
Query: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
P SALS A GPT P ++ + P P+PS P E P S
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
Query: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
S T P A P+ L P +S +A L+SP P+ +GTP + A
Sbjct: 87 S----GTALPLGTAPEAPTFLPNLIGP---PISPAALALASP-MIAPTLKGTPSSSA--- 135
Query: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG---TKARPVPP--PDNAAT 325
P L AL P V +K +A L+S P + SG T + P+ P P
Sbjct: 136 ---PLALVALAPHSV---QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
Query: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
+P+ + P+P +PS P + T+P TP + + + P P +
Sbjct: 190 KVPSEVVPNP---------KGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240
Query: 386 IPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445
I QV + S L +P +P +L SL+ S + +T S ++ Q A P+
Sbjct: 241 IASPQVKDTTISSVLISPQNPGSL-SLKGPVSPPAALSLSTQSLPVVTSSQKTA---GPN 296
Query: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
P P APL + +Q S LS P T+ + S S P
Sbjct: 297 TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP-TVKTISVDHS--STGASYPSQ 353
Query: 506 SLIMPPLETQSSLAP----------PSLQTPP---ASLTTPPLENLP-----SLAP-PPL 546
++PPL +++ + P PS+ P +S+T P +L SL+P L
Sbjct: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413
Query: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606
S+P T H P Q P S + T TP + P A + +
Sbjct: 414 ILKSSPNATYHY-------PLVAQMPVSSVGT----TPLVVTNPCTIAAAPTTTFEVATC 462
Query: 607 PSPPLS--PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664
SPP+S P++ P +P L + P+ +P+ P+ L+ P
Sbjct: 463 VSPPMSSGPISNIEPTSPAALVMAPV------------------APKEPSTQVATTLRIP 504
Query: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
SPP P P + P+ P SL P P + P+ P
Sbjct: 505 VSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS-PAQAGLTTKKDPTVLPLV 563
Query: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV--PPLLAAPPLQVPPSP-----PASLP 777
QA P +P Q S P P+SP AT + PL P SP AS+
Sbjct: 564 QAAPK-NSPSFQSTSSSP-EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVI 621
Query: 778 MSPLAKPPPQAPP----ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP------ 827
+ P A P +L TP + A P A G AP + + + A+P
Sbjct: 622 KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
Query: 828 --PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---P 882
P+ PV L +P P AS P P P + + P TL LAP P P
Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENC-----PVAPSPQNTCA-PLATLVLAPEIPKSVP 735
Query: 883 PPSRSPSSTLSGP---DLAGHSSS---ATSTPEELRGYDSGPEGGAAAS----------- 925
PS P+ T G D H+S+ S+P+E DSG A++
Sbjct: 736 SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795
Query: 926 ------------PP-------PDAEL----AACHPAAWSRGPAPPLAFRGAPGAPL---- 958
PP PD + + P S P L+F+G+ +P
Sbjct: 796 PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS 855
Query: 959 PWPPATGPGSADGLCTIYETEG---PESATPAPGALD-PGPSPGTSGGKAAAGAGAGASS 1014
P PP+ T +G P TP P ++ P P G + +S
Sbjct: 856 PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
Query: 1015 RSPKQARLGELPLG 1028
SPK+AR P G
Sbjct: 916 SSPKKARATPAPKG 929
Score = 142 bits (359), Expect = 1e-33
Identities = 293/1159 (25%), Positives = 408/1159 (35%), Gaps = 256/1159 (22%)
Query: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
+A P PP S ++ P + P SP + T P Q S+
Sbjct: 35 TAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQS----SSGTA 90
Query: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRP 200
+ G A EAP + GP P +P+ A T G P AP A
Sbjct: 91 LPLGTAPEAPT-------FLPNLIGP-PISPAALALASPMIAPTLKGTPSSSAPLALVAL 142
Query: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSA 259
+KS + T+ PS A +G + A + S T L+ P+ P+
Sbjct: 143 APHSVQKSSAFPPNLLTSPPSVAV---AESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP 199
Query: 260 RGTPRAP----------AHPSQPKPKGLQALRPPQVTPPR--KDAAPALGPLS-SSPLAT 306
+GTP P P G+ +L PQ TP A+P + + SS L +
Sbjct: 200 KGTPSPPCIVSTVPYHCVTPMASIQSGVASL--PQTTPTTTLAIASPQVKDTTISSVLIS 257
Query: 307 PSPSGTKA--RPVPPP--------------DNAATPLPATLPPSPPLATPLPLAP----- 345
P G+ + PV PP + T P T PP P++ LAP
Sbjct: 258 PQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNT-PPDFPISLGSHLAPLHQSS 316
Query: 346 -----------PSPSAPPSLQTL----PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390
PS + P+++T+ S A+ PSQ PP+ P + +P
Sbjct: 317 FGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQ---RSVIPPL--PSRNEVVPATV 371
Query: 391 VPHSLTSPSLQAPPSPLA------LSSLQATTSLG-SPTLQATHSFLTMSPRQTQASLTS 443
+ +PS+ PS ++ SL TS SPT T L SP T
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPT---TSLILKSSPNATYHYPLV 428
Query: 444 PSRPASTPPDSP-PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS----LASH 498
P S+ +P + P ++ A+P ++ VSP S I ++ S +A
Sbjct: 429 AQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPV 488
Query: 499 SPQAPLSSL-------IMPPLETQSSL------------APPSLQTPPASLTTPPLEN-- 537
+P+ P + + + PPL L LQT PASL P
Sbjct: 489 APKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQ 548
Query: 538 -----------LPSLAPPPLQTASAPLTTPHLETPPCP----------APCPLQAPPSPL 576
LP + P + S T+ E P P P P+ P S +
Sbjct: 549 AGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSM 608
Query: 577 TTPPPETPS-------SIATPPPQAP--------PALASPPLQGLPSPPLSP-----LAT 616
T+P S S A P P P +A+ PL+ ++P +T
Sbjct: 609 TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668
Query: 617 PPPQAPPXLALPPLQAPPSPPASP------PLSPLAT------PSPQAPNALAVHLLQAP 664
A P L AP + P PL P A+ PSPQ A L+ AP
Sbjct: 669 YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728
Query: 665 FSPP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS--- 719
P PSP + +PP + V + + AP +A+ P + P + + S
Sbjct: 729 EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP--VASSPKECPTEDSGASATASSKGT 786
Query: 720 ATPPPQAPPPL---AAPPLQVPPSPPASP-PMSPSATPPPRVPPLLAA------------ 763
T +P PL +P + PP+ S P +P V P+ A+
Sbjct: 787 LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846
Query: 764 ---PPLQVPPSPPASLPMSPLAKPPPQA------------PPALATPPLQALPSP---PA 805
P P+PP SP P P A P TP + LP P PA
Sbjct: 847 KDSPATTHSPTPP-----SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
Query: 806 S-FPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPL------LQVPPSPPASPTLQAPRR 857
+ P QAP S ++S P ATP P+ P +P PPSP P +P+
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961
Query: 858 PPTPGPDTSVSGPRLTLALAP-GPPPPPSRSPSSTLSGPDLAGHSSSATS---TPEELRG 913
PTP T S +P G P PP+ +P S GP + T TP +G
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 914 YDS-----------------GPEGGAAASPPPDAELAACHPAAW----SRGPAPPLAFRG 952
+ P+G AA+P P A PAA GPA P + +G
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKG--APTTPAATLPSPKGGPATP-SLKG 1078
Query: 953 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG--TSGGKAAAGAGA 1010
AP P PP+ G A T P+ A P A P P G T K A A
Sbjct: 1079 APTPPAATPPSPKGGPA--------TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 1011 GASSRSPKQARLGELPLGA 1029
A+ SPK P GA
Sbjct: 1131 -ATPPSPKGGLATPPPKGA 1148
Score = 129 bits (325), Expect = 1e-29
Identities = 169/628 (26%), Positives = 235/628 (37%), Gaps = 96/628 (15%)
Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG--RKPLAERAGG 64
K A TP + G T P G+P PP P+ G G P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 65 IGGATIPESAP-----------RAGPTRSAGTSSR--NPASRPPASGRGERAPPAKN--T 109
G T+P + P + GPT A T S PA PP+ RG P K T
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Query: 110 SPGPVS-SPGRASGT--TRPGPL----GQKGLRISAEETVARGKATEAPKRSALSAGARR 162
SP + SP +A T TR G G ++ + AT APK + ++
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 163 DTSGP--TPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
D + P TP +P PA + + ++ + PAP P P P SS E T
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPAT 1519
Query: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATP--------LSSPARSGPSARGTPRAPAHPS 270
P++RR P A + +L S TP L PA + PS + TP P
Sbjct: 1520 ---PSSRRDPIA-------PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
Query: 271 QP-KPKGLQALRPPQVTPPRKDAAPA-----LGPLSSSPLATPSPSGTKARPVPPPDNAA 324
P P +A PP VTP AP+ + P +SP +P+ P P A
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Query: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSL-----QTLPSPPATPPSQAPPSMTTPPMQA 379
TP P P SPP+ TP L SP++P S+ T+P P++ P+ + A
Sbjct: 1630 TPAPKGTPTSPPV-TPSSL-KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
Query: 380 P----PSLQTIPPIQVPHSLTSPSLQAP--PSPLALSSLQATTSLGSPTLQATHSFLTMS 433
P + T P + P + S + P P P A + + S +P +
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA--------PLL 1739
Query: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
P Q +S T+ + AS P P AP AS PL + V P ++ S
Sbjct: 1740 PVQKDSSKTAKGKDASHSPKGP--LAPPESKASTPLTAAAFEKVLPKPESASV------S 1791
Query: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPS----LQTPPASLTTPPLENLPSLAPP----- 544
+ S PL+ +P L + P S L++P L + L L PP
Sbjct: 1792 AAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISG 1851
Query: 545 --PLQTASAPLTTPHLETPPCPAPCPLQ 570
P Q+ + TP P P P Q
Sbjct: 1852 GVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879
Score = 119 bits (298), Expect = 2e-26
Identities = 171/664 (25%), Positives = 254/664 (38%), Gaps = 93/664 (14%)
Query: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368
P+ + P P + A P+ + L + L P P PP S P L + P +
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 369 PPSMTTPPMQAP----PSLQTIPPIQVPHSLT-SPSLQAPP-SPLAL---SSLQATTSLG 419
P ++ + P++ P S +P P + T P+L PP SP AL S + A T G
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
Query: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479
+P+ A + + ++P Q S P P L + P + + S +V
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFP---------------PNLLTSPPSVAVAESGSVIT 174
Query: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
LS+P+ +P P ++L P E + P +PP ++T P +
Sbjct: 175 LSAPI--------------APSEPKTNLNKVPSEVVPN--PKGTPSPPCIVSTVPYHCVT 218
Query: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
+A AS P TTP T A ++ P+ P S++ P +PPA
Sbjct: 219 PMASIQSGVASLPQTTP--TTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAAL 276
Query: 600 SPPLQGLPSPPLSPLATPPPQAPP--XLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
S Q LP S T P PP ++L AP + + L P A +
Sbjct: 277 SLSTQSLP-VVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT 335
Query: 658 VHLLQAPFS--------------PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703
V + S P PS P + A P V+PS S+ P
Sbjct: 336 VKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSP 395
Query: 704 ---LQVPPSPPASP------PMSPSAT--PPPQAPPPLAA----PPLQVPPSPPASPPMS 748
L V S SP SP+AT P A P+++ P + P A+ P +
Sbjct: 396 SGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT 455
Query: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
PP+ + P + P+ PA+L M+P+A P+ P L+ SPP P
Sbjct: 456 TFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA---PKEPSTQVATTLRIPVSPPLPDP 512
Query: 809 GQAPFSPSASLPMSP----LATPPPQ---APPVLAAPLLQVPPSPPASPTLQ-APRRPP- 859
PS+ L P L T P AP A L P P +Q AP+ P
Sbjct: 513 EDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPS 572
Query: 860 ----TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 915
+ P+ +S P TLA P P P+S+++ P L +SS++ + G D
Sbjct: 573 FQSTSSSPEIPLS-PEATLAKKSLGEPLPIGKPASSMTSP-LGVNSSASVIKTDSYAGPD 630
Query: 916 S-GP 918
S GP
Sbjct: 631 SAGP 634
Score = 80.5 bits (197), Expect = 8e-15
Identities = 119/461 (25%), Positives = 175/461 (37%), Gaps = 66/461 (14%)
Query: 528 ASLTTPPLENLPSLAPPPLQTASAPLTT------------PHLETPPCPAP--CPLQAPP 573
A+ T P E L P +TA P+++ P L P PAP CPL A
Sbjct: 5 ATETVPATEQ--ELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
Query: 574 SPLTTPPPETPSS--IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL---- 627
P P T +S + P PQ+ A P +P P PP +P LAL
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
Query: 628 --PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
P L+ PS A L LA S Q +A +LL SPP ++ S P+
Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT---SPPSVAVAESGSVITLSAPI 179
Query: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
+ PS+ +L P +V P+P +P P +T P P+A+ V S P +
Sbjct: 180 A-----PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGV-ASLPQT 233
Query: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
P + A P+V + L + P P SL + P +PPA + Q+LP
Sbjct: 234 TPTTTLAIASPQVKDTTISSVL-ISPQNPGSLSLK-----GPVSPPAALSLSTQSLPVVT 287
Query: 805 ASFPGQAPFS-PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863
+S P + P + + P Q+ L Q PS + PT+ +
Sbjct: 288 SSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTV---KTISVDHS 344
Query: 864 DTSVSGPRLTLALAPGPPPPPSRS---PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920
T S P + PP PSR+ P++ + P +A D GP
Sbjct: 345 STGASYPSQRSVI----PPLPSRNEVVPATVAAFPVVA-------------PSVDKGPST 387
Query: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961
++ + P L ++S P L + +P A +P
Sbjct: 388 ISSITCSPSGSLNVA--TSFSLSPTTSLILKSSPNATYHYP 426
Score = 56.2 bits (134), Expect = 2e-07
Identities = 88/306 (28%), Positives = 121/306 (39%), Gaps = 67/306 (21%)
Query: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALR-----------VLGAAGAVGRKPLAERA 62
A TP + G TP P G+P PPVTP++L+ +GA K L +
Sbjct: 1618 AVTPPSPEKGPATPAPKGTP-TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676
Query: 63 G-----GIGGATIPESAP-RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
G + A PES P PTR + ++ A+ PP P AKN S GP+S
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC----PDPSAKNGSKGPLS- 1731
Query: 117 PGRASGTTRPGPLGQKGLRISAEET-VARGK-ATEAPKRSALSAGARRDTSGPTPGTPSP 174
T P PL L + + + A+GK A+ +PK GP S
Sbjct: 1732 ------TVAPAPL----LPVQKDSSKTAKGKDASHSPK-------------GPLAPPESK 1768
Query: 175 AMARRSRAAGTEVGLPRP---APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
A + AA +V LP+P + SA P PP S+ A T P P + PS+
Sbjct: 1769 ASTPLTAAAFEKV-LPKPESASVSAAPSPPV-----SLPLAPSPVPTLP-PKQQFLPSSP 1821
Query: 232 GGLQRPASRSLS----SSATPLSSPARSGPSARGTPRAPAHPSQPKPK--GLQALRPPQV 285
G + S+ L+ PL P P + G P + P PK G+ P
Sbjct: 1822 GLVLESPSKPLAPADEDELLPLIPPE---PISGGVPFQSVLVNMPTPKSAGIPVPTPSAK 1878
Query: 286 TPPRKD 291
P K+
Sbjct: 1879 QPVTKN 1884
Score = 54.3 bits (129), Expect = 6e-07
Identities = 58/193 (30%), Positives = 75/193 (38%), Gaps = 35/193 (18%)
Query: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT---PPPRVPPLLA 762
+P + P + P PQA + P S +S +A P P +PP +
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVL----------PMSSALSVTAALGQPGPTLPPPCS 50
Query: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
P Q P L + A P P PS AS P + PF S+S
Sbjct: 51 PAPQQCP------LSAANQASPFPS-------------PSTIASTPLEVPFPQSSSGTAL 91
Query: 823 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
PL T P+AP L P L PP PA+ L +P PT S S P +ALAP
Sbjct: 92 PLGT-APEAPTFL--PNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ 148
Query: 883 PPSRSPSSTLSGP 895
S P + L+ P
Sbjct: 149 KSSAFPPNLLTSP 161
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 212 bits (540), Expect = 1e-54
Identities = 248/841 (29%), Positives = 321/841 (38%), Gaps = 165/841 (19%)
Query: 247 TPLSSPARSGPSARGTPRA-------PAHPS----QPKPKGLQALR-PPQVTPPRKDAAP 294
TP P + +G P+ P P + KP G ++ PQ+ P + P
Sbjct: 380 TPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP 439
Query: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
L P SPL+ P P PP A+ P PP P A P P A
Sbjct: 440 LLPPPEESPLSPPPEES----PTSPPPEASRLSP------PPEELP---ASPLPEALHLS 486
Query: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414
+ L P +PP + P+ PP P++ S SP ++PPSP
Sbjct: 487 RPLEESPLSPPPE------ESPLSPPPESSPFSPLE--ESPLSPPEESPPSP-------- 530
Query: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
+L +P +SP +AS SP P P SPP P LP SPP
Sbjct: 531 --ALETP----------LSP-PPEASPLSP--PFEESPLSPP---PEELPTSPP------ 566
Query: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT-----PPAS 529
P S LS P P+ + SP P +S + PP E +S L+PP ++ P AS
Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSP-PPEASRLFPPFE-ESPLSPPPEESPLSPPPEAS 624
Query: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP--SPLTTPPPETPSSI 587
+PP E+ P PP S P L P P L PP SPL+ PP E+P+S
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLS--PLPVVSRLSPPPEESPLSPPPEESPTS- 681
Query: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP-PASPPLSPLA 646
PPP+A L+ PP SPP PP ++LP ++P P P P L P +
Sbjct: 682 --PPPEA-SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Query: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAP-FSP----------PASPPVSPSATPPSQA 695
+P HL P P SP + P SP P P +SP A P +
Sbjct: 739 EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLS 798
Query: 696 P--------PSLAAPPLQVPPSPPASPP------MSPSATPPPQAP--------PPLAAP 733
P P P L P P P +SP + P +P P L P
Sbjct: 799 PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858
Query: 734 PLQV-PPSPPASPPMSPSAT-----PPPRVP---PLLAAPPLQVPPSPPAS-----LPMS 779
PL P PP P P+ PPP P PLL P L P PP S LP+S
Sbjct: 859 PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS 918
Query: 780 PLAKP---PPQAPPALATPPLQAL---PSPPASFP-GQAPFSPSASLPMSPLATPPPQAP 832
P +P P PP PPL + +PPA P G+ + P P++P
Sbjct: 919 PSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEY------PFGAKGDSDPESP 972
Query: 833 PVLAAPLLQVPPSPPASPTLQAPR------RPPTPGPDTSVSGPRLTLALAPGPPP---- 882
LAAP+L+ P SPP P PP+PG + P L L P P
Sbjct: 973 --LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030
Query: 883 --PPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAA 939
P SP S S P L S S ++ G D + E A P+A
Sbjct: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090
Query: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL-DPGPSPG 998
S P+P G P P P + D + E P APG+ +PG +PG
Sbjct: 1091 TSPLPSP----MGDLSCPAPSPAP----ALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPG 1142
Query: 999 T 999
+
Sbjct: 1143 S 1143
Score = 212 bits (539), Expect = 2e-54
Identities = 234/819 (28%), Positives = 296/819 (36%), Gaps = 111/819 (13%)
Query: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
LP P S PP E P AS S A P A L RP S P
Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH-LSRPLEES------P 493
Query: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLATP 307
LS P P + +P P + P L PP+ +PP +PAL PLS P A+P
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESP-----LSPPEESPP----SPALETPLSPPPEASP 544
Query: 308 -SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP---SPSAPPSLQTLPSPPAT 363
SP ++ PPP+ T P P P++PP SP +PP + PP
Sbjct: 545 LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Query: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP----LALSSLQATTSLG 419
+PP + P+ PP + P ++ P ++P SP LS L + L
Sbjct: 605 ESPLSPPPEES-PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663
Query: 420 SPTLQATHSFLTMSPRQTQASLTSP---SRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
P ++ +SP ++ + P SR + P DSP P PASPP + SL
Sbjct: 664 PPPEES-----PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSL--- 715
Query: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
+S PL PL L P++ L P E P L P P
Sbjct: 716 ---MSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE-------PHLSPRPEEPHLSPQA 765
Query: 537 NLPSLAPPPLQ-----TASAPLTTPHLETPP-CPAPCPLQAPP---SPLTTPPPETPSSI 587
P L+P P + P +P E P P P L P P +P PE P
Sbjct: 766 EEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS 825
Query: 588 ATP------PPQAPPALASPPLQG-----LPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636
P P P L+ P + L PPLSP PP+ P P P
Sbjct: 826 PQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Query: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQA 695
P P LSPL L L P PP SP P + P SP P +SP PP
Sbjct: 886 PGEPSLSPL----------LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL 935
Query: 696 PPSLAAPPLQVPPSPPASPPMSPSATP-----PPQAPPPLAAPPLQVPPSPPAS------ 744
PP L+ P+ +PPA P+ P PLAAP L+ P SPP
Sbjct: 936 PPPLS--PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDP 993
Query: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
P+ P PP P+ A P+ + P PP P+ + P +PP+ +PP L P
Sbjct: 994 EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS 1053
Query: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
P S + + T P A P P L P P P D
Sbjct: 1054 PLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALD 1113
Query: 865 TSVSGPRLTLAL----APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920
T L APG P P ++P S S +L G S PEEL
Sbjct: 1114 DFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLAS--ELKG--SPVLLDPEEL--------- 1160
Query: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 959
A P C A P AP AP P
Sbjct: 1161 ---APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
Score = 192 bits (488), Expect = 1e-48
Identities = 226/737 (30%), Positives = 290/737 (39%), Gaps = 148/737 (20%)
Query: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
LQ PL + +Q L +P + L P ++ S P S PP++ L
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMP--LLPPPEESPLSPPPEESPTSPPPEASRLSP 469
Query: 460 PLS-LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSL 518
P LPASP P LS PL PL + SP P S PLE +S L
Sbjct: 470 PPEELPASP------LPEALHLSRPLEESPLSPPPEESPLSP--PPESSPFSPLE-ESPL 520
Query: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP--- 575
+PP P +L TP L+PPP ++PL+ P E+P P P L P P
Sbjct: 521 SPPEESPPSPALETP-------LSPPP---EASPLSPPFEESPLSPPPEELPTSPPPEAS 570
Query: 576 -LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL--SPLATPP---PQAPPX----L 625
L+ PP E+P S PPP+ P ++ PP PP SPL+ PP P +PP L
Sbjct: 571 RLSPPPEESPMS---PPPEESP-MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
Query: 626 ALPPLQAPPSP-----PASPP-----LSPLATPS----PQAPNALAVHLLQAPFSPPPS- 670
+ PP +P SP P SPP LSPL S P + L+ ++P SPPP
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEA 686
Query: 671 -----PPVQAPFSPPASPPVSPSATPPSQAPPSL---AAPPLQVPPSP------------ 710
PP +P SPP P SP++ PP + SL +P L +P P
Sbjct: 687 SRLSPPPEDSPTSPP--PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
Query: 711 --PASPPMSPSATPP---PQAPPPLAAPPLQVP--PSPPASPPMSPSATPPPRVP----- 758
P P +SP P PQA P +P + P + P P +SP A P P
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804
Query: 759 ---PLLAAPPLQVPPSPPASLP------MSPLAKPPPQAP--------PALATPPLQALP 801
P P L P P P +SP ++ P +P P L PPL P
Sbjct: 805 HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP 864
Query: 802 SPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
P PGQ P LP+ P PP P P+L P L P PP SP P
Sbjct: 865 EKPPEEPGQCP--APEELPLFP---PPGEPSLSPLLGEPALSEPGEPPLSPL-------P 912
Query: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919
P + P L+ L P P PP SP T + P A P +G DS PE
Sbjct: 913 EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP-ALSPLGELEYPFGAKG-DSDPE 970
Query: 920 GGAAA-------SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL---------PWPPA 963
AA SPPP+A P PP+ +PG+P+ P PP
Sbjct: 971 SPLAAPILETPISPPPEANCT-------DPEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 964 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 1023
P L + + P +P P PSP + GK G A + ++
Sbjct: 1024 CSPLLQHSL--VPQNSPPSQCSP-PALPLSVPSPLSPIGK-VVGVSDEAELHEMETEKVS 1079
Query: 1024 ELPLGALQASVVQHLLS 1040
E AL+ S L S
Sbjct: 1080 EPECPALEPSATSPLPS 1096
Score = 187 bits (475), Expect = 5e-47
Identities = 274/995 (27%), Positives = 355/995 (35%), Gaps = 182/995 (18%)
Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK---------- 56
KA+ G R+ A + + + P P P P AL V G
Sbjct: 351 KAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG 410
Query: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
PL A +G A + + P A + P PP P TSP P +S
Sbjct: 411 PLQCEAKPLGKAGV-----QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS 465
Query: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
R S P + + + P+ S LS P P + +
Sbjct: 466 --RLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS---------PPPESSPFSP 514
Query: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPS 229
S + E P PA PP E S +S E T P P A R
Sbjct: 515 LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR--- 571
Query: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQ---V 285
L P S S P SP P A R P P P P+ PP+ +
Sbjct: 572 ----LSPPPEES-PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
Query: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
+PP +D +P P SP+ +P P ++ P+P + P P PL+ P +P
Sbjct: 627 SPPPED-SPMSPPPEESPM-SPPPEVSRLSPLPVVSRLSPP-----PEESPLSPPPEESP 679
Query: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP--SLQTIPPIQVPHSLTSPSLQAP 403
SP PP L PP P+ PP P PP SL ++P + SP L P
Sbjct: 680 TSP--PPEASRLSPPPEDSPTSPPPE--DSPASPPPEDSLMSLPLEE------SPLLPLP 729
Query: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP--L 461
P Q P L +SPR + L S A P SP + P
Sbjct: 730 EEP------QLCPRSEGPHLSPRPEEPHLSPRPEEPHL---SPQAEEPHLSPQPEEPCLC 780
Query: 462 SLPASPPLQTSL-SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
++P P L P +SP L + P Q S P+ P S P +S L+P
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSP-QTEEPHLSPVPEEPCLS----PQPEESHLSP 835
Query: 521 PSLQTPPASLTTPPLENL-PSLAPPPLQTASAPLTTPHLETPP-CPAPCPLQAPPSPLTT 578
S + P P +L P L PPL +P E PP P CP AP
Sbjct: 836 QSEE--PCLSPRPEESHLSPELEKPPL--------SPRPEKPPEEPGQCP--APEELPLF 883
Query: 579 PPPETPSSIATPPPQAPPALA---SPPLQGLP---------SPPLSPLATPPPQAPPXLA 626
PPP PS P PAL+ PPL LP P LSP PP PP L+
Sbjct: 884 PPPGEPS---LSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS 940
Query: 627 LPPLQAPPSPPASPPLSPLATP-------SPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
P+ +PPA PL L P P++P LA +L+ P SPPP P
Sbjct: 941 --PIITAAAPPALSPLGELEYPFGAKGDSDPESP--LAAPILETPISPPPEANCTDP--- 993
Query: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739
PV P PPS P A P+ + P PP P+ + P +PP +PP +P
Sbjct: 994 ---EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP-ALPL 1049
Query: 740 SPPASPPMSP---------------SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
S P+ P+SP T P A P P P PM L+ P
Sbjct: 1050 SVPS--PLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPS---PMGDLSCP 1104
Query: 785 PPQAPPAL--------ATPPLQALPSPPAS-FPGQAPFSPSASLPMSPLATPPPQAPPVL 835
P PAL T PL + +P + PGQ P S ++ L SP+ P + PV
Sbjct: 1105 APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV- 1163
Query: 836 AAPLLQVPPSPPASPTLQAPRRPPTPG---PDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
+P P T G P PR AP P PP+ S +
Sbjct: 1164 -------------TPMEVYPECKQTAGQGSPCEEQEEPR-----APVAPTPPTLIKSDIV 1205
Query: 893 SGPDLAGHSSSATSTP--EELRGYDSGPEGGAAAS 925
+ ++ S P E L G PEGG + S
Sbjct: 1206 NEISNLSQGDASASFPGSEPLLG-SPDPEGGGSLS 1239
Score = 156 bits (394), Expect = 1e-37
Identities = 173/592 (29%), Positives = 240/592 (40%), Gaps = 111/592 (18%)
Query: 525 TPPASLTTPPLE-NLPSLAPPPLQTA-SAPLTTPHLETPPCPAPCPLQA----------- 571
TP S +PP + P+ P L A H+ + P PLQ
Sbjct: 366 TPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQ 425
Query: 572 ----------------PP---SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL- 611
PP SPL+ PP E+P+S PPP+A + SPP + LP+ PL
Sbjct: 426 LEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS---PPPEA--SRLSPPPEELPASPLP 480
Query: 612 -----------SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
SPL+ PP ++P L+ PP +P SP PLSP SP +P
Sbjct: 481 EALHLSRPLEESPLSPPPEESP--LSPPPESSPFSPLEESPLSP-PEESPPSP------A 531
Query: 661 LQAPFSPPP-SPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
L+ P SPPP + P+ PF P SPP T P L+ PP + P SPP P SP
Sbjct: 532 LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEESP 589
Query: 719 SATPPPQAP---PPLAAPPLQVPP--SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
+PPP+A PP PL PP SP + PP + +PPP P ++ PP + P SPP
Sbjct: 590 -MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP-MSPPPEESPMSPP 647
Query: 774 ------ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASLPMSPL 824
+ LP+ PPP+ P L+ PP ++ SPP +P SP++ P
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESP-LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Query: 825 ATPPPQ----APPVLAAPLLQVPPSPPASPTLQAPR---RPPTPGPDTSVSGPRLTLA-- 875
A+PPP+ + P+ +PLL +P P P + P RP P P L+
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
Query: 876 ---LAPGP--------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924
L+P P P P SP + GP L+ +P+ + S
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQA--EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 925 SPPPDAELAACHPAAWSRGPAPPLA-----FRGAPGAPLPWPPATGPGS--ADGLCTIYE 977
SP P+ + P P + P +P P P PG A ++
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
Query: 978 TEGPESATP---APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 1026
G S +P P +PG P + + + +G S SP+ LP
Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
Score = 116 bits (291), Expect = 1e-25
Identities = 196/784 (25%), Positives = 259/784 (33%), Gaps = 194/784 (24%)
Query: 331 LPPSP-PLATPLPLAPP-----SPSAPPSLQTLPSPPATPPSQAPPSMTTPP---MQAPP 381
+PP P L +P P A P SP+ P L T PP+ + P +P ++ PP
Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165
Query: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
+ P Q P L AP PL PR A
Sbjct: 2166 QVPAQVPSQDPFGL------APAYPL-------------------------EPRFPTAPP 2194
Query: 442 TSPSRPAST-PPDSPPLQAPLSLP-ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
T P P+ T P PP+ S P A P + +P +P P T P
Sbjct: 2195 TYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL--------K 2246
Query: 500 PQAP-LSSLIMP--PLETQSSLAPPSLQTPPASLTTPPLE--------NLPSLAPPPLQT 548
P+ P L +L +P P + P L PP + LE + PS PP L
Sbjct: 2247 PRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF 2306
Query: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
+P + HL P +AP +P + + P + PPA A P S
Sbjct: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP-----S 2361
Query: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
PP P P A PPL P PP PP S A P
Sbjct: 2362 PPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCALP-------------------- 2399
Query: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-ATPPPQAP 727
P P P + P SP + SQ+P + P P ++ PS TP Q+P
Sbjct: 2400 ---PRSLPSDPFSRVPASPQSQSSSQSP---------LTPRPLSAEAFCPSPVTPRFQSP 2447
Query: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP------PASLPMSPL 781
P + PP + P + P +P PP PP +A + + PA+LP P
Sbjct: 2448 DPYSRPPSR----PQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
Query: 782 ----AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA---PPV 834
AK P PP PG F + TP P P
Sbjct: 2504 GELHAKVPSGQPPNFVRS------------PGTGAF----------VGTPSPMRFTFPQA 2541
Query: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 894
+ P L+ P P P PGP ++ P+ T PS SP SG
Sbjct: 2542 VGEPSLKPPVPQPGLPPPHGINSHFGPGP--TLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599
Query: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA-ACHPAAWSRGPAPPLAFRGA 953
+ S P L P PD L H A+ G P+ R
Sbjct: 2600 STGESYGLSPLRPPSVL------------PPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647
Query: 954 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 1013
PG TG GS+ + PG DPG S G
Sbjct: 2648 PG--------TGMGSS------------LATAELPGTQDPGMS----------GLSQTEL 2677
Query: 1014 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGG-GPGGAEGGGVTGGAR 1072
+ ++ RL EL +++ + R L E AA +G GP G+ G + A
Sbjct: 2678 EKQRQRQRLREL--------LIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAF 2729
Query: 1073 AALS 1076
LS
Sbjct: 2730 EQLS 2733
Score = 111 bits (277), Expect = 4e-24
Identities = 178/685 (25%), Positives = 236/685 (34%), Gaps = 117/685 (17%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
L+P P SP PPP + + + P+ R + PE +P + P +
Sbjct: 626 LSPPPEDSPMSPPP-EESPMSPPPEVSRLSPLPVVSRL-----SPPPEESPLSPPPEES- 678
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
P S PP + R P TSP P SP
Sbjct: 679 -----PTSPPPEASRLSPPPEDSPTSPPPEDSP--------------------------- 706
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-APSARPRPPTE 203
A+ P+ S +S P P P R+ G + PRP P PRP E
Sbjct: 707 --ASPPPEDSLMSLPLEESPLLPLPEEPQLC----PRSEGPHLS-PRPEEPHLSPRP--E 757
Query: 204 GPRKSVSSASEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGPSARG 261
P S + H + +P P P + LS L SP P
Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKD---AAPAL--GPLSSSPLATPSPSGTKARP 316
P P QP+ L PR + +P L PLS P P G P
Sbjct: 818 VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAP 877
Query: 317 ------VPPPDNAATPL---PATLPPSPPLATPLP-LAPPSPSAPPSLQTLPSPPATPPS 366
PP + + +PL PA P P +PLP P SPS PSL SP PP
Sbjct: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL----SPQLMPPD 933
Query: 367 QAPPSMT-TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
PP ++ APP+L + ++ P S P SPLA L+ SP +A
Sbjct: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDS--DPESPLAAPILETPI---SPPPEA 988
Query: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS--- 482
P + PS + P SP L PL SP LQ SL P SP S
Sbjct: 989 N----CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP 1044
Query: 483 ---PLTI-HPLQALSSLASHSPQAPLSSLIMPPL-ETQSSLAPPSLQTP----------P 527
PL++ PL + + S +A L + + E + PS +P P
Sbjct: 1045 PALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCP 1104
Query: 528 ASLTTPPLENLPSLA--PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
A P L++ L PL AP + P E P + SP+ P E
Sbjct: 1105 APSPAPALDDFSGLGEDTAPLDGIDAPGSQP--EPGQTPGSLASELKGSPVLLDPEEL-- 1160
Query: 586 SIATPPPQAPPALASPPLQGLP----SPPLSPLATPPPQ------APPXLALPPLQAPPS 635
P + P QG P P +P+A PP L A S
Sbjct: 1161 -APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS 1219
Query: 636 PPASPPLSPLATPSPQAPNALAVHL 660
P S PL L +P P+ +L++ L
Sbjct: 1220 FPGSEPL--LGSPDPEGGGSLSMEL 1242
Score = 107 bits (266), Expect = 8e-23
Identities = 228/927 (24%), Positives = 301/927 (32%), Gaps = 181/927 (19%)
Query: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
+PG LG +A T+ G T S + G + +G PG SP
Sbjct: 2109 QPGALGSPPP--AAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 185 TEVGLPR-------PAPSARPR----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
+P PA PR PPT P S + A P A RP AG
Sbjct: 2167 VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP---PMLGASSRPGAG-- 2221
Query: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAP-----AHPSQPKPKGLQALRPPQVTPP 288
+P + TP P+ P + PR P A P P G +A P PP
Sbjct: 2222 --QPGEFHTTPPGTPRHQPSTPDPFLK--PRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Query: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
++ AL + L SPS PP+ P++ L P +P
Sbjct: 2278 FGESRKAL-EVKKEELGASSPS------YGPPNLGFVDSPSSGTHLGGLELKTPDVFKAP 2330
Query: 349 SAPPSLQTLPSPPATP--PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
P + Q P P P + PP+ P +PPS P I P S T P Q P +P
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAP--SPPSH---PDIFRPGSYTDPYAQPPLTP 2385
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
RP PP+S P SLP+
Sbjct: 2386 ---------------------------------------RPQPPPPESCCALPPRSLPSD 2406
Query: 467 PPLQTSLSP-AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
P + SP + S SPLT PL A + S P++ P + P +
Sbjct: 2407 PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS-----PVTPRFQSPDPYSRPPSRPQSRD 2461
Query: 526 PPASLTTPPLENLP-------SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578
P A L PP P SLA L P P A P PP+ + +
Sbjct: 2462 PFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRS 2521
Query: 579 PPPETPSSIATPPPQA---PPALASPPLQGLPSPPLSPLATPPPQA-----PPXLALPPL 630
P T + + TP P P A+ P L+ PP+ PPP P L
Sbjct: 2522 PG--TGAFVGTPSPMRFTFPQAVGEPSLK----PPVPQPGLPPPHGINSHFGPGPTLGKP 2575
Query: 631 QAPPSPPAS----PPLSPLATPSPQAPNALAVHLLQAP-FSPPPSPPVQAPF-SPPASP- 683
Q+ A+ P SPL S + + L+ P PPP+P P+ S AS
Sbjct: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
Query: 684 -----PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ------------- 725
PV P + SLA L P S Q
Sbjct: 2636 SGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQI 2695
Query: 726 -------------APPPLAAPPLQ--VPPSPPASPPMSPSATP---PPRVPPLLAAPP-- 765
A PP PS PA +S TP L+ PP
Sbjct: 2696 QRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSK 2755
Query: 766 LQVPPSPPASLPMSP-LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
L P P S P L++PPP A P+ + L +F +AP+ SLP+
Sbjct: 2756 LSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY--PGSLPLQQQ 2813
Query: 825 ATPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRR----------PPTPGPDTSVSGP-- 870
Q AA ++ S P++P + R+ PGP V GP
Sbjct: 2814 QQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAG 2873
Query: 871 ---------RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
+ L PG P P + P ++ PE LRG
Sbjct: 2874 PAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVS--EDPHRLAPEGLRGLAVSGLPP 2931
Query: 922 AAASPPPDAEL-AACHPAAWSRGPAPP 947
S PP EL + HP ++GP P
Sbjct: 2932 QKPSAPPAPELNNSLHPTPHTKGPTLP 2958
Score = 94.0 bits (232), Expect = 7e-19
Identities = 239/959 (24%), Positives = 319/959 (33%), Gaps = 155/959 (16%)
Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE-----R 61
+ K G AR A L P PG+ PPP + + G A+
Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146
Query: 62 AGGIGGATIP-ESAPRAGPTRSAGTSSRNPASRPPA---SGRGERAPPAKNTSPGPVSSP 117
AG + G P E + P A S++P PA R APP P P +P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206
Query: 118 GR---ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
+ ++RPG GQ G T G P R P +
Sbjct: 2207 AQPPMLGASSRPG-AGQPG----EFHTTPPGTPRHQPSTPDPFLKPR------CPSLDNL 2255
Query: 175 AMARRSRAAGTEVGLP--RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG- 231
A+ G + P P P R E +K AS S P+ PS+G
Sbjct: 2256 AVPESPGVGGGKASEPLLSPPPFGESRKALE-VKKEELGASSPSYGPPNLGFVDSPSSGT 2314
Query: 232 --GGLQRPASRSLSSSATPLSS---PARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQV 285
GGL+ + TP +S P G R PA P P RP
Sbjct: 2315 HLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY 2374
Query: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
T P A P L P RP PPP + LP PS P + +P +P
Sbjct: 2375 TDPY--AQPPLTP----------------RPQPPPPESCCALPPRSLPSDPFSR-VPASP 2415
Query: 346 PSPSA--------PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
S S+ P S + P TP Q+P + PP + P S P+ P
Sbjct: 2416 QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-PQSRDPFAPLHKP----- 2469
Query: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---S 454
P Q P SL A TSLG+ A L P A P+ PP+ S
Sbjct: 2470 PRPQPPEVAFKAGSL-AHTSLGAGGFPAA---LPAGP----AGELHAKVPSGQPPNFVRS 2521
Query: 455 PPLQAPLSLPASPPLQTSLSPAVS--PLSSPLTIHPLQALSSLASH--------SPQAPL 504
P A + P+ P++ + AV L P+ L + SH PQ+
Sbjct: 2522 PGTGAFVGTPS--PMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTN 2579
Query: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP 564
++ S PS + S PL PS+ PPP S P + H +
Sbjct: 2580 YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP-PSVLPPPAPDGSLPYLS-HGASQRSG 2637
Query: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP----------L 614
P++ P T SS+AT P P + GL L L
Sbjct: 2638 ITSPVEKREDPGT----GMGSSLAT---AELPGTQDPGMSGLSQTELEKQRQRQRLRELL 2690
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF--SPPPSPP 672
Q A + PP S A PS A L+ Q PF + S
Sbjct: 2691 IRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRG--QTPFAGTQDKSSL 2748
Query: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP------SATPPPQA 726
V P S + P + P + P + L+ PP PP+ P+S ++ S +A
Sbjct: 2749 VGLPPSKLSGPILGPGSFP---SDDRLSRPP---PPATPSSMDVNSRQLVGGSQAFYQRA 2802
Query: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
P P + PLQ + +AT + A + P +P L L P
Sbjct: 2803 PYP-GSLPLQQQQQQLWQQQQATAAT------SMRFAMSARFPSTPGPELGRQALGSPLA 2855
Query: 787 QAPPALATPPLQALPSP--PASF------------PGQAPFSPSASLPMSPLATPPPQAP 832
L P + +P P PA F PG PF P P P P + P
Sbjct: 2856 GISTRLPGPG-EPVPGPAGPAQFIELRHNVQKGLGPGGTPF-PGQGPPQRPRFYPVSEDP 2913
Query: 833 PVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
LA L+ +PP P++P AP + P GP L L PP S
Sbjct: 2914 HRLAPEGLRGLAVSGLPPQKPSAP--PAPELNNSLHPTPHTKGPTLPTGLELVNRPPSS 2970
Score = 89.0 bits (219), Expect = 2e-17
Identities = 202/837 (24%), Positives = 283/837 (33%), Gaps = 99/837 (11%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
P T P P P P PA +LGA+ +P A + G T P PR P
Sbjct: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGASS----RPGAGQPGEFH--TTPPGTPRHQP-- 2238
Query: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ--KGLRISAE 139
S+ +P +P A P SPG V + P P G+ K L + E
Sbjct: 2239 ----STPDPFLKPRCPSLDNLAVPE---SPG-VGGGKASEPLLSPPPFGESRKALEVKKE 2290
Query: 140 ETVARGKATEAPKRSAL-SAGARRDTSGPTPGTP----SPAMARRSRAAGTEVGL----- 189
E A + P + S + G TP +P R S+ GL
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
Query: 190 -PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS---S 245
P PA + P PP+ S ++ +P R +P RSL S S
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTD-PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS 2409
Query: 246 ATPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
P S ++S + TPR A A P Q+ P P R + PL
Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469
Query: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
P P KA + A PA LP P A L PS PP+ P A
Sbjct: 2470 PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP--AGELHAKVPS-GQPPNFVRSPGTGA 2526
Query: 363 TPPSQAPPSMTTPPMQAPPSLQTIPP---IQVPHSLTS-----PSLQAPPSP---LALSS 411
+ +P T P PSL+ P + PH + S P+L P S +A +
Sbjct: 2527 FVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGN 2586
Query: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP------PDSPPLQAPLSLPA 465
+ S P+ +T +SP + + L P+ S P + +P+
Sbjct: 2587 FHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
Query: 466 SPP--LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
P + +SL+ A P + + L Q LI ++ +
Sbjct: 2647 DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKET 2706
Query: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP---P 580
A PP + P + S TP T + L PPS L+ P P
Sbjct: 2707 AAAAAGAVGPPGSWGAEPSSPAFEQLSRG-QTPFAGTQDKSSLVGL--PPSKLSGPILGP 2763
Query: 581 PETPSS--IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
PS ++ PPP A P+ + S L + Q P PLQ
Sbjct: 2764 GSFPSDDRLSRPPPPATPSSMD-----VNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLW 2818
Query: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
+ AT A +A + P +P P QA SP A +S P + P
Sbjct: 2819 QQQQATAATSMRFAMSA------RFPSTPGPELGRQALGSPLAG--ISTRLPGPGEPVPG 2870
Query: 699 LAAPPLQVPPSPPASPPMSPSATP-PPQAPP------PLAAPPLQVPP------SPPASP 745
A P + + P TP P Q PP P++ P ++ P + P
Sbjct: 2871 PAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLP 2930
Query: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM-------SPLAKPPPQAPPALATP 795
P PSA P P + L P P+ P L + + L +P P A A P
Sbjct: 2931 PQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLP 2987
Score = 82.8 bits (203), Expect = 2e-15
Identities = 222/984 (22%), Positives = 314/984 (31%), Gaps = 201/984 (20%)
Query: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGT 123
AT S + GP + GT+ + A+ P GE P S P P +S
Sbjct: 4037 ATEGPSTHQGGPL-AIGTTPESMATEP-----GEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
Query: 124 TRPGPL---GQKGLRISAEETVARGKATEAPKRSALSAG------ARRDTS-GPTPGTPS 173
+P PL GQ+ ++S T G + S+ A A+ S G PG+ +
Sbjct: 4091 LQP-PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149
Query: 174 PAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
+ + L RP + P+PP GP P+ R G
Sbjct: 4150 QNLLGPQQPM-----LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGV 4204
Query: 233 GLQRPASRSLSSS------ATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQV 285
+ P R LS A + + + R TP +Q P +GL +P
Sbjct: 4205 LAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG 4264
Query: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
P P GPL A P P G P PP + P+ + P+PP ++P
Sbjct: 4265 GFP----GPQTGPLQELG-AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR 4319
Query: 346 PSPSAPPSLQTLPSPPATPPSQ-APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA-- 402
PS PS Q LP+ PP+ P P ++ PP + Q+ +L S L
Sbjct: 4320 PSQLPSPSSQ-LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWD 4378
Query: 403 PPSPLALSSLQATTSL---------GSPTLQATHSFLTMSPRQTQASLTSPS--RPASTP 451
PP LA + +SL G +A+ + PR+ +L + S R A+
Sbjct: 4379 PPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE 4438
Query: 452 PDSPP-------LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504
P P L P S LQ L LS+ L+A + S A L
Sbjct: 4439 PIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGL 4498
Query: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS-----------------LAPPPLQ 547
+ + A TP + L S L +
Sbjct: 4499 EQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQE 4558
Query: 548 TASAPLTTPHLET-----PPCPAPCPLQA-------------PPSP------LT----TP 579
+ PLT P + P + CP+ P P LT +
Sbjct: 4559 LSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSN 4618
Query: 580 PPETPSSI-ATPPPQAPPALAS--PPLQGLPSPP------------------------LS 612
PP PSS+ TPPP + + P + L P L+
Sbjct: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
Query: 613 PLATPPPQAPPXLALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
L TPP + + + SP PAS P S L +P+ P+ + Q +
Sbjct: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738
Query: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP----- 723
P P+ S P P P + P L + S ++ SA
Sbjct: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNG 4798
Query: 724 ---------------------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA 762
P++P P + P P P L
Sbjct: 4799 VMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLK 4858
Query: 763 APPLQVP--------------------PSPP---------ASLPMSPLAKPPPQAPPALA 793
+P P PP ++L + L+ PPP+ P
Sbjct: 4859 QFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP---- 4914
Query: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
+PP PSP A P P P LP PLA PP +P LA+ P P A P +
Sbjct: 4915 SPP----PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
Query: 854 A-PRRPPTPGPDTSVSGPRLTLAL 876
RPP V RL L L
Sbjct: 4971 GEDSRPPRLKKWKGVRWKRLRLLL 4994
Score = 77.0 bits (188), Expect = 9e-14
Identities = 178/773 (23%), Positives = 244/773 (31%), Gaps = 116/773 (15%)
Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG--PTRSAG 84
PRP G PR P P P AL G V P P S+P+ P++
Sbjct: 4281 PRPQGPPRLPAP--PGALSTGPVLGPVHPTP-------------PPSSPQEPKRPSQLPS 4325
Query: 85 TSSRNP--ASRPPAS-GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI-SAEE 140
SS+ P A PP G + P PG VS T L KGL +
Sbjct: 4326 PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADT----LFSKGLGPWDPPD 4381
Query: 141 TVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSR----AAGTEV------GL 189
+A T+ P++S+L G +G P ++ + R A G + G
Sbjct: 4382 NLAE---TQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE 4438
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P AP GPR GL+ + + S L
Sbjct: 4439 PIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGL 4498
Query: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPAL-----G 297
+ PS + A P PKPK +Q V+ +K A+ AL
Sbjct: 4499 EQKLQGTPSNK-EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQ 4557
Query: 298 PLSSSPLATPSPSGTKARPVP----PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353
LS PL P+ + + P P N + L LP P S +
Sbjct: 4558 ELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGA-----LPTGPDYYSQLLT 4612
Query: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
L +PP TPPS PP T PP + + P + + A S AL
Sbjct: 4613 KNNLSNPP-TPPSSLPP--TPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669
Query: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
SL L P + DSP P S P S +
Sbjct: 4670 EVKSL---------DLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPES--ILGEE 4718
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
+P L S +ALS + P+A + + P + +L P L
Sbjct: 4719 APRFPHLGSGRWEQEDRALSPVIPLIPRASIP--VFPDTKPYGALG----LEVPGKLPVT 4772
Query: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
E + T SA A P+ PE+P+ T P +
Sbjct: 4773 TWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKK 4832
Query: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
+GL ++P + P P
Sbjct: 4833 GEAEGPGGKEKGLEG----------------------KSPDTGPDWLKQFDAVLPGYTLK 4870
Query: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPAS---------PPVSPSATPPSQAPPSLAAPPL 704
+ L + L SP P PP Q ++ S PP + PPS PS A+PP
Sbjct: 4871 SQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPT 4930
Query: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
+ P P P A PP +P PLA+ P P P A PP + PPR+
Sbjct: 4931 E----PLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979
Score = 76.3 bits (186), Expect = 2e-13
Identities = 211/914 (23%), Positives = 304/914 (33%), Gaps = 159/914 (17%)
Query: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE---APKRSALSAGARRDTSG 166
S G + S + ++ P L Q + + + G T+ P++ L + +T G
Sbjct: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLGDQP----GSMTQNLLGPQQPMLERPMQNNT-G 4169
Query: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP---TEGPRKSVSSASEHSTTEPSPA 223
P P P P + G VG+ R + + P+ S + +
Sbjct: 4170 PQPPKPGPVLQSGQGLPG--VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQ 278
R+ + Q P + + +PL P G P P Q P+P+G
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG-- 4285
Query: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL-PATLP-PSPP 336
PPR A P G LS+ P+ P P PPP + P P+ LP PS
Sbjct: 4286 --------PPRLPAPP--GALSTGPVLGP------VHPTPPPSSPQEPKRPSQLPSPSSQ 4329
Query: 337 LATPLPLAPPSPSAP----PSLQTLP---SPPATPPSQAPPSMTTPPMQAPPSL-QTIPP 388
L T L P P P P+L+ P SP A + S P P +L +T P
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
Query: 389 IQ---VPHSLTSPSLQAPPSPLALSSLQATT----SLGSPTLQ------------ATHSF 429
Q VP L + Q P LS Q +LG+ +++ ++
Sbjct: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449
Query: 430 LTMSPRQT------QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ--------TSLSP 475
L PR Q L + + ST S L+A ++ L T +
Sbjct: 4450 LLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNK 4509
Query: 476 AVSPLSSPLTIHPLQ---ALSSLASHSPQ------APLSSLIMPPLETQSSLAP---PSL 523
+ PLT P + A L S + S ++ L+ + SL P P++
Sbjct: 4510 EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAI 4569
Query: 524 QTPPASLTTPPLENLPSLAPPPLQTA-------------SAPLTTPHLETPPCPAPCPLQ 570
T SL P P L+ A S LT +L PP P P
Sbjct: 4570 -TANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTP---PSS 4625
Query: 571 APPSPLTTPPPE---------TPSS-IATPPPQAPPALASPPLQGLPSPP-----LSPLA 615
PP TPPP TPS + P A A S S L+ L
Sbjct: 4626 LPP----TPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALP 4681
Query: 616 TPPPQAPPXLALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
TPP + + + SP PAS P S L +P+ P+ + Q + P
Sbjct: 4682 TPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVI 4741
Query: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
P+ S P P P + P L + S ++ SA +
Sbjct: 4742 PLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMV 4801
Query: 732 APP----LQVPPSPPASPPMSPSATPPPRVPPLLAAP-------PLQVPPSPPASLPMSP 780
A +++P S P SP+ P + P + P L
Sbjct: 4802 AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFD 4861
Query: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLAAPL 839
P L L SP P Q ++ + S L + L+ PPP+ P +PL
Sbjct: 4862 AVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPL 4921
Query: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP-PPSRSPSSTLSGPDLA 898
P SPP P ++ P P LA P P P P + SP S P
Sbjct: 4922 APSPASPPTEPLVELPTEP---------------LAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 899 GHSSSATSTPEELR 912
S P L+
Sbjct: 4967 PPEEGEDSRPPRLK 4980
Score = 75.5 bits (184), Expect = 3e-13
Identities = 173/701 (24%), Positives = 238/701 (33%), Gaps = 132/701 (18%)
Query: 16 TPAARAP--GLLTPRPPGSPRP------PPP--VTPAALRVLGAAGAVGRKP------LA 59
+P+++ P L P PG+P+P PPP V+PAA ++ + G P LA
Sbjct: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
Query: 60 ERAGGIGGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PV 114
E + +P + P S + + P P A G A K + G P+
Sbjct: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALG----AQSVKREANGEPI 4440
Query: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
+PG ++ GP + G + + + R K + S G R + +G
Sbjct: 4441 GAPGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG-SEGLRAEINGHID----- 4492
Query: 175 AMARRSRAAGTE---VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
S+ AG E G P A R P K V AS+ S + R G
Sbjct: 4493 -----SKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLV---SSRKKLRKEDG 4544
Query: 232 GGLQRPASRSLSS--SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
+ L S PL+ PA + + P P + + L+ P
Sbjct: 4545 VRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQ-LRGAFGSGALPTG 4603
Query: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPD------NAATPLP--ATLPPSPPLATPL 341
D L L+ + L+ P + P PPP N TP P A
Sbjct: 4604 PDYYSQL--LTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDS 4661
Query: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
A S SL L + P TPP + + S +I P P S+ +
Sbjct: 4662 ERALRDTSEVKSLDLLAALP-TPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGE--E 4718
Query: 402 APPSPLALSSLQATTSLGSPTLQ----ATHSFLTMSPRQTQASLTSPSRPASTP--PDSP 455
AP P LGS + A + + PR AS P PD+
Sbjct: 4719 APRFP----------HLGSGRWEQEDRALSPVIPLIPR------------ASIPVFPDTK 4756
Query: 456 PLQA-PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
P A L +P P+ T S +S LT+ A + A L S+ +P +
Sbjct: 4757 PYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIP--NS 4814
Query: 515 QSSLAPPSLQTPPASLTTPPLE---------------NLPSLAPP---------PLQTAS 550
L P S PA T P + P P P T
Sbjct: 4815 YEVLFPES----PARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLK 4870
Query: 551 APLTTPHLETPPCPAPCP----------LQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
+ L L PAP P L+ PPPE PS PP P+ AS
Sbjct: 4871 SQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS---PPPSPLAPSPAS 4927
Query: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
PP + L P PLA PP +P LA P A P P A PP
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
Score = 74.7 bits (182), Expect = 5e-13
Identities = 124/506 (24%), Positives = 166/506 (32%), Gaps = 56/506 (11%)
Query: 435 RQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
+Q Q L + SR +P Q L +PA P + SSP + P L
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP---------LQHFSSPGALGPTLLL 4021
Query: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
+ ++ +SS T P ++ T P S+ T P E PSL+ P
Sbjct: 4022 TGKEQNTVDPAVSSEATEGPSTHQG-GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQP 4080
Query: 553 LTTPHLET----PPCPAPCPLQAPPSPLTTPPP----ETPSSIATPPPQAPPALASPPLQ 604
P + PP P Q S L T + S ++ P LA P +
Sbjct: 4081 QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
Query: 605 GLPSP---------PLSPLATPPPQ----APPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
P P P+ P Q P P LQ+ P + + Q
Sbjct: 4141 LGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
Query: 652 APNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAP-------- 702
LA + SP +QA + TPP Q P + +P
Sbjct: 4201 LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ 4260
Query: 703 -PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP---PASPPMSPSATPPPRVP 758
L P P P A P PQ PP L APP + P P P PS+ P+ P
Sbjct: 4261 PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320
Query: 759 PLLAAPPLQVPPSP--PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
L +P Q+P P + P +P + P PP P A + G P+ P
Sbjct: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
Query: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 876
+L + P L QV P Q PR P G +
Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEP------CALGAQSVKRE 4434
Query: 877 APGPP-PPPSRSPSSTLSGP-DLAGH 900
A G P P S L+GP AGH
Sbjct: 4435 ANGEPIGAPGTSNHLLLAGPRSEAGH 4460
Score = 60.1 bits (144), Expect = 1e-08
Identities = 122/504 (24%), Positives = 159/504 (31%), Gaps = 103/504 (20%)
Query: 506 SLIMPPLETQSSLA-PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPPC 563
+L+ P + Q +A P + P + P +L P L T T P + +
Sbjct: 3983 TLLSPQQQQQQQVALGPGMPAKPLQHFSSP----GALGPTLLLTGKEQNTVDPAVSSEAT 4038
Query: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
P Q P + T TP S+AT P + P+L+ L P P PQ
Sbjct: 4039 EGPSTHQGGPLAIGT----TPESMATEPGEVKPSLSGDSQLLLVQPQ------PQPQPSS 4088
Query: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
PPL+ P L A L S S P A P
Sbjct: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHG------QLGSGSSSEASSVPHLL-----AQP 4137
Query: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
VS P S L P P PM + P P P P+ LQ P
Sbjct: 4138 SVSLGDQPGSMTQNLLG------PQQPMLERPMQNNTGPQPPKPGPV----LQSGQGLPG 4187
Query: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA------------KPPPQAPPA 791
M ++ +LA P SP + L + PP P
Sbjct: 4188 VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG 4247
Query: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPL-ATPPPQAPPVLAAPLLQVPPSPPASP 850
T PLQ L G F + P+ L A P PQ PP L AP + P P
Sbjct: 4248 TQTSPLQGLLGCQPQLGG---FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP 4304
Query: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
PTP P + P P PS+ PS + P A + TP+
Sbjct: 4305 V------HPTPPPSS------------PQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK- 4345
Query: 911 LRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968
P+G PP AA A +S+G P W P
Sbjct: 4346 -------PQGPTLEPPPGRVSPAAAQLADTLFSKGLGP-------------WDPPDN--- 4382
Query: 969 ADGLCTIYETEGPESATPAPGALD 992
+ ET+ PE ++ PG LD
Sbjct: 4383 ------LAETQKPEQSSLVPGHLD 4400
Score = 59.7 bits (143), Expect = 2e-08
Identities = 90/336 (26%), Positives = 115/336 (34%), Gaps = 60/336 (17%)
Query: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV-PPSPPASLPMSP--LAKPPPQAPPA 791
L++PP P A +PPP AAP + + P+ PA L S KPP + P
Sbjct: 2104 LRIPPQPGAL------GSPPPA-----AAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152
Query: 792 LATPP---LQALPSPPASFPGQAPFSPSASLPMSP-LATPPPQAPPVLAA-------PLL 840
+P L+ P PA P Q PF + + P+ P T PP PP + P+L
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPML 2212
Query: 841 QVPPSPPA--------SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
P A +P +P TP P P L P P S L
Sbjct: 2213 GASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL 2272
Query: 893 SGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASP------------PPDAELAACH 936
P G S A +E G S P G SP PD A
Sbjct: 2273 LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT 2332
Query: 937 PAAWSRGP-APPLAFRGAPGAP----LPWPPATGPGSADGLCTIYETEGPESATPAPG-- 989
P A P +P L R P P PP+ G T + P + P P
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392
Query: 990 ----ALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021
AL P P + A + +SS+SP R
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR 2428
Score = 39.7 bits (91), Expect = 0.016
Identities = 78/327 (23%), Positives = 101/327 (30%), Gaps = 47/327 (14%)
Query: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
P + A PLQ SP A P P + PS P++ TP
Sbjct: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPES- 4057
Query: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
+A P +V PS + L +P PQ P+ LQ PP PGQ S
Sbjct: 4058 ----MATEPGEVKPSLSGDSQLL-LVQPQPQPQPS----SLQL--QPPLRLPGQQQQQVS 4106
Query: 817 ASLPM---------SPLATPPPQAPPVLAAPLLQVPPSP---------PASPTLQAPRR- 857
S ++ P +LA P + + P P P L+ P +
Sbjct: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN 4166
Query: 858 -----PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
PP PGP + + P ++ P L S + L
Sbjct: 4167 NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL 4226
Query: 913 GYDSGPEGGAAASPPPDAELAA-CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971
+ A PP E P G P L G PG P TGP G
Sbjct: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG--GFPG------PQTGPLQELG 4278
Query: 972 LCTIYETEGPESATPAPGALDPGPSPG 998
+GP PGAL GP G
Sbjct: 4279 AGP--RPQGPPRLPAPPGALSTGPVLG 4303
Score = 34.3 bits (77), Expect = 0.68
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 14/87 (16%)
Query: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
AP P PP SP P P +P ++ + +PLAE +P P A
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLV----ELPTEPLAE-------PPVPSPLPLASSP 4956
Query: 81 RSAGTSSRNPASRPPASGRGERAPPAK 107
SA P +RPP G R P K
Sbjct: 4957 ESA---RPKPRARPPEEGEDSRPPRLK 4980
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 196 bits (499), Expect = 8e-50
Identities = 177/632 (28%), Positives = 241/632 (38%), Gaps = 103/632 (16%)
Query: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
TP P T PSPP + L P + +PP+ T PP T PS + TTPP PS
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS-- 1455
Query: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
PPI + T+P PSP + TT+ PT T T T+P
Sbjct: 1456 --PPIS---TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTT----------TPPPTTTP 1500
Query: 445 SRPASTP--PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
S P +TP P + P + SPP T+ +P + SP T P+ +S + P
Sbjct: 1501 SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560
Query: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT----PHL 558
S P T ++ PP+ P + TTP + + PPP T S P TT P
Sbjct: 1561 TPS-----PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615
Query: 559 ETPPCPAPCPLQAPPSPLTTPPPETPS----SIATPPPQAPPALASPPLQGLPSPPLSPL 614
TP P P+ P S T PP TPS + TPPP P SPP PSPP++
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSPPITTT 1672
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPV 673
TPPP P P+ PSPP + +P T +P +P + P S PSPP
Sbjct: 1673 TTPPPTTTPS---SPITTTPSPPTTTMTTPSPTTTPSSP----ITTTTTPSSTTTPSPPP 1725
Query: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAP-PPL 730
+P + SP T + PP+ + PL P PP+ P SP +T P P PL
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPL 1785
Query: 731 ---------AAPPLQVPP----------SPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771
P P P + +S AT P V P Q+ +
Sbjct: 1786 CNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDV------PIGQLGQT 1839
Query: 772 PPASLPMSPLAKPPPQAP------------------------PALATPPLQALPSPPASF 807
+ + + K Q P P T P+PP +
Sbjct: 1840 VVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTT 1899
Query: 808 P----GQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPT 860
P +P+ + +P TP V P Q P + P + T P
Sbjct: 1900 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1959
Query: 861 PGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 891
G T + P T + P P P +++P++T
Sbjct: 1960 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1991
Score = 192 bits (487), Expect = 2e-48
Identities = 144/436 (33%), Positives = 176/436 (40%), Gaps = 68/436 (15%)
Query: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
+T+PS P +TP SPP P S PP T P + + P T P
Sbjct: 1396 ITTPSPPTTTP--SPP---PTSTTTLPPTTTPSPPTTTTTTPPPTTTP------------ 1438
Query: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
PP+ T ++ P + +PP S TT PPP T S P TTP +
Sbjct: 1439 --------SPPITTTTTPPPTTTPSPPISTTT---------TPPPTTTPSPPTTTP---S 1478
Query: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP-PLQGLPSPPLSPLATPPP 619
PP P P P + TTPPP T S T P PPA + P PSPP + TPPP
Sbjct: 1479 PPTTTPSP---PTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP 1535
Query: 620 QAPPXLALPPLQAPPSPPASPP-LSPLATPSPQAPNALAVHLLQAPFSPP----PSPPVQ 674
P PP P +PP S L P TPSP P SPP PSPP
Sbjct: 1536 TTTPS---PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP-SPPTTTTPSPPTI 1591
Query: 675 APFSPPA----SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
+PP SPP + + TPP PS PP P +PP S P T P P
Sbjct: 1592 TTTTPPPTTTPSPPTTTTTTPPPTTTPS---PPTTTPITPPTSTTTLPPTTTPSPPPTTT 1648
Query: 731 AAPPLQVPPSPPA----SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
PP PSPP SPP++ + TPPP P + P+ PSPP + +P P
Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP---SSPITTTPSPPTTTMTTPSPTTTP 1705
Query: 787 QAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
+P TP PSPP P + P P T P ++PL P
Sbjct: 1706 SSPITTTTTPSSTTTPSPP---PTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762
Query: 846 PPASPTLQAPRRPPTP 861
P +P +P TP
Sbjct: 1763 PSITPPTFSPFSTTTP 1778
Score = 183 bits (464), Expect = 9e-46
Identities = 223/956 (23%), Positives = 326/956 (34%), Gaps = 172/956 (17%)
Query: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
+ TP PP + PPP + T+P + + PT +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTT--------------------------TLPPTTTPSPPTTTT 1429
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
T PP + PP T P+S+ TT P P
Sbjct: 1430 TTPPPTTTPSPPITTT--TTPPPTTTPSPPISTTTTPPPTTTPSP--------------- 1472
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
T +P + S T+ P TPSP + LP P+ P PPT
Sbjct: 1473 -PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP---PTTTPSPPTT 1528
Query: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSGPSARGT 262
+TT P P P + P S +L + TP P + T
Sbjct: 1529 ------------TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322
+P + P P + PP T P + P + P TPSP T P+ PP +
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTP---SPPTTTTTTPPPTTTPSPPTT--TPITPPTS 1631
Query: 323 AATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT-----PPSQAPPS-MTTPP 376
T P T P PP T P PP+ + P T PSPP T PP+ P S +TT P
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTP--PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689
Query: 377 MQAPPSLQTIPPIQVPHS----LTSPSLQAPPS--PLALSSLQATTSLGSPTLQATHSFL 430
++ T P P S T+PS PS P +++ TT+ PT T
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT---- 1745
Query: 431 TMSPRQTQASL-TSPSRPASTPPDSPPLQAPLSLPASPPL-------------------Q 470
T+ P T + L T+P P+ TPP P PL
Sbjct: 1746 TLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGD 1805
Query: 471 TSLSPAV------SPLSSPLTIHPLQALSSL-------------ASHSPQAPLSSLIMP- 510
T L V + +S T++P + L + Q P + M
Sbjct: 1806 TELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAF 1865
Query: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570
L + ++ T P ++TT EN P + P+TT T P P P Q
Sbjct: 1866 CLNYEINVQCCECVTQPTTMTTTTTEN-------PTPPTTTPITTTTTVT-PTPTPTGTQ 1917
Query: 571 AP---PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627
P P TT TP+ T P P + + P+P + T P
Sbjct: 1918 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1977
Query: 628 PP-----LQAPPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFSPPPSPP-VQAPFS 678
P Q P + P + + TP+P Q P + +P P+P Q P +
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2036
Query: 679 PP--ASPPVSPSATPPSQAPPSLA--APPLQVPPSP-------PASPPMSPSATPPPQAP 727
P + V+P+ TP P+ V P+P P + P++ + T P
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2096
Query: 728 PPLAAPPLQVP--PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP-----PASLPMSP 780
P P P + +P +P+ T P P+ + P+P P + P++
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156
Query: 781 LAK-PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839
P P TP + + P +P+ + +P TP V P
Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPT 2211
Query: 840 ---LQVPPSPPASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 891
Q P + P + T P G T + P T + P P P +++P++T
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2267
Score = 183 bits (464), Expect = 9e-46
Identities = 118/366 (32%), Positives = 157/366 (42%), Gaps = 35/366 (9%)
Query: 573 PSPLTTPPPETPSSIATPPPQAPPA-----LASPPLQGLPSPPLSPLATPPPQAPP---- 623
PSP TT P P+S T PP P+ +PP PSPP++ TPPP P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 624 -XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682
PP PSPP + P P TPSP P + PSPP P +PPAS
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT-----PPPTTTPSPPTTTPITPPAS 1513
Query: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP---SATPPP---QAPPP--LAAPP 734
P T PS + PP PSPP + P++P + T PP +PPP PP
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573
Query: 735 LQVPPSPPA----SPPMSPSATPPPRVPP-----LLAAPPLQVPPSPPASLPMSPLAKPP 785
PSPP SPP + TPPP P PP PSPP + P++P
Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633
Query: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
P +PP +PP + P + + S P++ TPPP P ++P+ P
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP--SSPITTTPSP 1691
Query: 846 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905
P + T +P P+ P T+ + P T +P P + SP++T S P + T
Sbjct: 1692 PTTTMTTPSPTTTPS-SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPT 1750
Query: 906 STPEEL 911
+T L
Sbjct: 1751 TTSSPL 1756
Score = 174 bits (441), Expect = 4e-43
Identities = 217/1037 (20%), Positives = 347/1037 (33%), Gaps = 105/1037 (10%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3333 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3385
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3445
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3499
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3557 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 3734 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ P + Q P ++ P+ T +++ P T + TT P+ ++ P P
Sbjct: 3793 VTPTPTPTGT-----QTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3843
Query: 546 LQTAS-APLTTPHLETP---PCPAPCPLQAP---PSPLTTPPPETPSSIATPPPQAPPAL 598
T + P TTP T P P P Q P P TT TP+ T P P
Sbjct: 3844 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3903
Query: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPLATPSP--- 650
+ + P+P + T P P Q P + P + + TP+P
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3963
Query: 651 QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA--APPLQ 705
Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3964 QTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4022
Query: 706 VPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSATPPPR 756
V P+P P + P++ + T P P P P + +P +P+ T P
Sbjct: 4023 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4082
Query: 757 VPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALPSPPASFPGQ 810
P+ + P+P P + P++ P P TP + + P
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-- 4140
Query: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870
+P+ + +P TP V P +P +P PTP P + +GP
Sbjct: 4141 ---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP 4197
Query: 871 RLTLALAP------GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924
+ AP PPP S +P ++ S S++ ST P +
Sbjct: 4198 PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST--------LPPAIEMTS 4249
Query: 925 SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA 984
+ PP A + PP PG P TG SA T+ +T +
Sbjct: 4250 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSSSAPTPSTV-QTTTTSAW 4307
Query: 985 TPAPGALDPGPSPGTSG 1001
TP P L T+G
Sbjct: 4308 TPTPTPLSTPSIIRTTG 4324
Score = 171 bits (433), Expect = 4e-42
Identities = 206/934 (22%), Positives = 319/934 (34%), Gaps = 149/934 (15%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
P TP PP + PP TP S P T
Sbjct: 1465 PPTTTPSPPTTTPSPPTTTP-------------------------------SPPTTTTTT 1493
Query: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
T++ +P + P + PPA T+ P ++P + TT P
Sbjct: 1494 PPPTTTPSPPTTTPIT------PPASTTTLPPTTTPSPPTTTTTTPP------------- 1534
Query: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
T +P + T+ P TPSP + T P P + P PP
Sbjct: 1535 ---PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT--PSPPTTTTPSPP 1589
Query: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
T +++ + TT PSP P+ P + + TP++ P +
Sbjct: 1590 T------ITTTTPPPTTTPSP-----PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
T +P + P PP T P +P + ++ P T S P PP
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTTTP----SPPITTTTTPPPTTTPSSPITTTPSPPTT 1694
Query: 322 NAATPLPATLPPSP------PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
TP P T P SP P +T P PP+ PS T PSPP T + PP+ T+
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS 1754
Query: 376 PMQAPPSLQTI-PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
P+ P +I PP P S T+P+ P L + G P +
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVP----LCNWTGWLDSGKPNFHKPGGDTELIG 1810
Query: 435 RQTQAS-LTSPSRPASTPPDSPPLQAPLSLPASP-----------------PLQTSLSPA 476
+ S A+ PD P Q ++ P+ L+
Sbjct: 1811 DVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYE 1870
Query: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
++ P +++ + +P P ++ P+ T +++ P T + TT P+
Sbjct: 1871 INVQCCECVTQP-TTMTTTTTENPTPPTTT----PITTTTTVTPTPTPTGTQTPTTTPIT 1925
Query: 537 NLPSLAPPPLQTAS-APLTTPHLET---PPCPAPCPLQAP---PSPLTTPPPETPSSIAT 589
++ P P T + P TTP T P P P Q P P TT TP+ T
Sbjct: 1926 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1985
Query: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSP 644
P P + + P+P + T P P Q P + P + +
Sbjct: 1986 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2045
Query: 645 LATPSP---QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPS 698
TP+P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2046 TPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2104
Query: 699 LA--APPLQVPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPM 747
V P+P P + P++ + T P P P P + +P
Sbjct: 2105 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164
Query: 748 SPSATPPPRVPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALP 801
+P+ T P P+ + P+P P + P++ P P TP +
Sbjct: 2165 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224
Query: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRP 858
+ P +P+ + +P TP V P Q P + P + T P
Sbjct: 2225 TTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279
Query: 859 PTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 891
G T + P T + P P P +++P++T
Sbjct: 2280 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313
Score = 162 bits (410), Expect = 2e-39
Identities = 191/925 (20%), Positives = 313/925 (33%), Gaps = 93/925 (10%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 1930 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 1982
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 1983 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2042
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2043 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2096
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2154 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 2331 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2389
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ P + Q P ++ P+ T +++ P T + TT P+ ++ P P
Sbjct: 2390 VTPTPTPT-----GTQTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440
Query: 546 LQTAS-APLTTPHLET---PPCPAPCPLQAP---PSPLTTPPPETPSSIATPPPQAPPAL 598
T + P TTP T P P P Q P P TT TP+ T P P
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500
Query: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPLATPSP--- 650
+ + P+P + T P P Q P + P + + TP+P
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560
Query: 651 QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA--APPLQ 705
Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2561 QTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619
Query: 706 VPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSATPPPR 756
V P+P P + P++ + T P P P P + +P +P+ T P
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679
Query: 757 VPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALPSPPASFPGQ 810
P+ + P+P P + P++ P P TP + + P
Sbjct: 2680 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-- 2737
Query: 811 APFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSV 867
+P+ + +P TP V P Q P + P + T P G T
Sbjct: 2738 ---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2794
Query: 868 SGP-RLTLALAPGPPPPPSRSPSST 891
+ P T + P P P +++P++T
Sbjct: 2795 TTPITTTTTVTPTPTPTGTQTPTTT 2819
Score = 162 bits (410), Expect = 2e-39
Identities = 191/925 (20%), Positives = 313/925 (33%), Gaps = 93/925 (10%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2298 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2350
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2410
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2411 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2464
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2522 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2698
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 2699 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ P + Q P ++ P+ T +++ P T + TT P+ ++ P P
Sbjct: 2758 VTPTPTPT-----GTQTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808
Query: 546 LQTAS-APLTTPHLET---PPCPAPCPLQAP---PSPLTTPPPETPSSIATPPPQAPPAL 598
T + P TTP T P P P Q P P TT TP+ T P P
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868
Query: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPLATPSP--- 650
+ + P+P + T P P Q P + P + + TP+P
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928
Query: 651 QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA--APPLQ 705
Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2929 QTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2987
Query: 706 VPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSATPPPR 756
V P+P P + P++ + T P P P P + +P +P+ T P
Sbjct: 2988 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047
Query: 757 VPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALPSPPASFPGQ 810
P+ + P+P P + P++ P P TP + + P
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-- 3105
Query: 811 APFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSV 867
+P+ + +P TP V P Q P + P + T P G T
Sbjct: 3106 ---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162
Query: 868 SGP-RLTLALAPGPPPPPSRSPSST 891
+ P T + P P P +++P++T
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTT 3187
Score = 162 bits (410), Expect = 2e-39
Identities = 191/925 (20%), Positives = 313/925 (33%), Gaps = 93/925 (10%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2666 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2832
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2890 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3066
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 3067 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3125
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ P + Q P ++ P+ T +++ P T + TT P+ ++ P P
Sbjct: 3126 VTPTPTPT-----GTQTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176
Query: 546 LQTAS-APLTTPHLET---PPCPAPCPLQAP---PSPLTTPPPETPSSIATPPPQAPPAL 598
T + P TTP T P P P Q P P TT TP+ T P P
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236
Query: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPLATPSP--- 650
+ + P+P + T P P Q P + P + + TP+P
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296
Query: 651 QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA--APPLQ 705
Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3297 QTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3355
Query: 706 VPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSATPPPR 756
V P+P P + P++ + T P P P P + +P +P+ T P
Sbjct: 3356 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3415
Query: 757 VPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALPSPPASFPGQ 810
P+ + P+P P + P++ P P TP + + P
Sbjct: 3416 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-- 3473
Query: 811 APFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSV 867
+P+ + +P TP V P Q P + P + T P G T
Sbjct: 3474 ---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530
Query: 868 SGP-RLTLALAPGPPPPPSRSPSST 891
+ P T + P P P +++P++T
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTT 3555
Score = 162 bits (410), Expect = 2e-39
Identities = 191/925 (20%), Positives = 313/925 (33%), Gaps = 93/925 (10%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3086
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3146
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3147 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3200
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3258 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 3435 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3493
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ P + Q P ++ P+ T +++ P T + TT P+ ++ P P
Sbjct: 3494 VTPTPTPT-----GTQTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3544
Query: 546 LQTAS-APLTTPHLET---PPCPAPCPLQAP---PSPLTTPPPETPSSIATPPPQAPPAL 598
T + P TTP T P P P Q P P TT TP+ T P P
Sbjct: 3545 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604
Query: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPLATPSP--- 650
+ + P+P + T P P Q P + P + + TP+P
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3664
Query: 651 QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA--APPLQ 705
Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3665 QTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723
Query: 706 VPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSATPPPR 756
V P+P P + P++ + T P P P P + +P +P+ T P
Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783
Query: 757 VPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALPSPPASFPGQ 810
P+ + P+P P + P++ P P TP + + P
Sbjct: 3784 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-- 3841
Query: 811 APFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSV 867
+P+ + +P TP V P Q P + P + T P G T
Sbjct: 3842 ---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3898
Query: 868 SGP-RLTLALAPGPPPPPSRSPSST 891
+ P T + P P P +++P++T
Sbjct: 3899 TTPITTTTTVTPTPTPTGTQTPTTT 3923
Score = 161 bits (407), Expect = 4e-39
Identities = 141/482 (29%), Positives = 181/482 (37%), Gaps = 79/482 (16%)
Query: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661
P+ + P P TP P LPP P SPP + TP P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTP-----SPPTTTTTTPPP----------- 1434
Query: 662 QAPFSPPPSPPVQAPFSPPA----SPPVSPSATPPSQAPPSLAAPPLQVPPSPPA---SP 714
+ PSPP+ +PP SPP+S + TPP PS P PSPP SP
Sbjct: 1435 ----TTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPS----PPTTTPSPPTTTPSP 1486
Query: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
P + + TPPP P +PP P +PPAS P T P PP PSPP
Sbjct: 1487 PTTTTTTPPPTTTP---SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPT 1543
Query: 775 SLPMSP----LAKPP---PQAPPALAT---------PPLQALPSPPASFPGQAPFSPSAS 818
+ P++P PP P PP T PP PSPP P + + S
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Query: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT----- 873
P + TPPP P +P P +PP S T P P+P P T+ + P T
Sbjct: 1604 PPTTTTTTPPPTTTP---SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660
Query: 874 LALAPGPP------PPPSRSPSS----TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 923
P PP PPP+ +PSS T S P + S T+TP + P
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTT 1720
Query: 924 ASPPP-----DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 978
SPPP + P + PP +P P PP+ P + T T
Sbjct: 1721 PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT-TSSPLTTTPLPPSITPPTFSPFSTTTPT 1779
Query: 979 EGPESATPAPGALDPGP----SPGTSGGKAAAGAGAG-ASSRSPKQARLGELPLGALQAS 1033
G LD G PG G G A++ S + ++P+G L +
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQT 1839
Query: 1034 VV 1035
VV
Sbjct: 1840 VV 1841
Score = 156 bits (395), Expect = 9e-38
Identities = 208/991 (20%), Positives = 334/991 (33%), Gaps = 146/991 (14%)
Query: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
TP+ TP P +P PP TP+ + P T P +
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTT---TTPPPTTT 1617
Query: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
+ PT + T + + PP + PP T+P P ++P + TT P+
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSP--PPTTTTTPPPTTTPSPPTTTTPSPPI------ 1669
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLP-- 190
T T P + + T+ TP TPS + + + T P
Sbjct: 1670 ----TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725
Query: 191 ----RPAPSARPRPPTEG----PRKSVSSA---------------SEHSTTEPSPAARRR 227
P+P+ P PPT P + SS S STT P+
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPL 1785
Query: 228 PSAGGGLQ--RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP------------- 272
+ G L +P + G +A + RA +P P
Sbjct: 1786 CNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVS 1845
Query: 273 ----------KPKGL----------------QALRPPQV---TPPRKDAAPALGPLSSSP 303
KP G+ + + P T P P++++
Sbjct: 1846 VGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTT 1905
Query: 304 LATPSPS--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
TP+P+ GT+ P T P P T P+ + P T P
Sbjct: 1906 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1965
Query: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGS 420
T P ++T P T PI ++T +P+ +P TT +
Sbjct: 1966 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2025
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPAST-PPDSPPLQAPLSLPASPPLQTSLSPAVSP 479
PT T + T +P T ++T P T P + P+ ++ +P + +P +P
Sbjct: 2026 PTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2084
Query: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
+++ T+ P + Q P ++ P+ T +++ P T + TT P+
Sbjct: 2085 ITTTTTVTPTPTPT-----GTQTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTT 2135
Query: 540 SLAPPPLQTAS-APLTTPHLET---PPCPAPCPLQAP---PSPLTTPPPETPSSIATPPP 592
++ P P T + P TTP T P P P Q P P TT TP+ T P
Sbjct: 2136 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2195
Query: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----LQAPPSPPASPPLSPLAT 647
P + + P+P + T P P Q P + P + + T
Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255
Query: 648 PSP---QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA- 700
P+P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2256 PTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314
Query: 701 -APPLQVPPSP-------PASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPS 750
V P+P P + P++ + T P P P P + +P +P+
Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374
Query: 751 ATPPPRVPPLLAAPPLQVPPSP-----PASLPMSPLAK-PPPQAPPALATPPLQALPSPP 804
T P P+ + P+P P + P++ P P TP + +
Sbjct: 2375 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434
Query: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTP 861
P +P+ + +P TP V P Q P + P + T P
Sbjct: 2435 TVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2489
Query: 862 GPDTSVSGP-RLTLALAPGPPPPPSRSPSST 891
G T + P T + P P P +++P++T
Sbjct: 2490 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520
Score = 136 bits (343), Expect = 1e-31
Identities = 172/817 (21%), Positives = 265/817 (32%), Gaps = 117/817 (14%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3632 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3684
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3744
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3798
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3856 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3912
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3972
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 3973 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4032
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 4033 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4091
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ P + Q P ++ P+ T +++ P T + TT P+ ++ P P
Sbjct: 4092 VTPTPTPTGT-----QTPTTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4142
Query: 546 LQTAS-APLTTPHLETP---PCPAPCPLQAPPS-PLTTP----PPETPSSIATPPP---- 592
T + P TTP T P P P Q P + P+TT P TP+ T PP
Sbjct: 4143 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTS 4202
Query: 593 ----------QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP- 641
PP ++P S PL+ T PP + + APPS P +P
Sbjct: 4203 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST-APPSTPTAPTT 4261
Query: 642 ------LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
LSP + + P S P VQ + +P +P +TP
Sbjct: 4262 TSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIR 4321
Query: 696 PPSLAAPPLQV-----------PPSPPA-------------------------SPPMSPS 719
L P V P S P +PS
Sbjct: 4322 TTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPS 4381
Query: 720 ATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSATPP 754
TP P P + P P P+P PP P PP
Sbjct: 4382 PTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPP 4418
Score = 126 bits (316), Expect = 1e-28
Identities = 154/748 (20%), Positives = 246/748 (32%), Gaps = 75/748 (10%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3701 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3753
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3754 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3813
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3867
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3925 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3981
Query: 310 S--GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
+ GT+ P T P P T P+ + P T P T P
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041
Query: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
++T P T PI ++T +P+ +P TT +PT T
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101
Query: 427 HSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
+ T +P T ++T P T P + P+ ++ +P + +P +P+++ T
Sbjct: 4102 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT-PPASLTTPPLENLPSLAPP 544
+ P + Q P ++ I + P QT PP +T P+ L + PP
Sbjct: 4161 VTPTPTPTGT-----QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP 4215
Query: 545 P-------LQTASAPLT--TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
P ++ S+PLT T L T P APPS T P + +PPP
Sbjct: 4216 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 4275
Query: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655
+ P +G + S P P P+P ++P + P +
Sbjct: 4276 TSPPGTPTRGTTTGSSS---APTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSV 4332
Query: 656 LAVHLLQAPFSPPPSPPVQAPFSPPA----------------SPPVSPSATP-PSQAPPS 698
L +L + P + S P +PS TP PS++ P+
Sbjct: 4333 LICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPT 4392
Query: 699 LAAP-PLQVPPSPPASPPMSPSATPPPQ 725
+ P P+P PP P PP Q
Sbjct: 4393 PSKPSSTPSKPTPGTKPPECPDFDPPRQ 4420
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 182 bits (463), Expect = 1e-45
Identities = 182/585 (31%), Positives = 219/585 (37%), Gaps = 102/585 (17%)
Query: 352 PSLQTLPSPPATPPS--QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
P + LP P PP P + + S + I H T Q PP P
Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP--- 814
Query: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469
SL + G P Q HS T + S++S + + P PPL S + P L
Sbjct: 815 -SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL 873
Query: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
V P PL + L S A P PPL+ L PP P A
Sbjct: 874 GM-----VPPPPPPLPGMTVPTLPSTAIPQP---------PPLQGTEMLPPPPPPLPGAG 919
Query: 530 LTTPP-LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP----PPETP 584
+ PP L L PPL A P PP P P PP PL PP P
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIP--------PPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
Query: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
+ PPP P A PP PPL PPP P +PP PP P A P
Sbjct: 972 GAGIPPPPPLPGAGIPPP------PPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIP--- 1020
Query: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704
P P P A PP PP+ PP PP+ + PP P PP
Sbjct: 1021 ---PPPPLPGA----------GIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPP- 1065
Query: 705 QVPPSP----PASPPMSPSATPPPQAPPPLAAPPLQVPPSP----PASPPMSPSATPPPR 756
PP P P PP+ + PPP P PP PP P P PP+ + PPP
Sbjct: 1066 -PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGVGIPPPPPLPGAGIPPP- 1121
Query: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
PPL P +PP PP LP + + PPP + PP P P A P P P
Sbjct: 1122 -PPL---PGAGIPPPPP--LPGAGIPPPPPLPRVGIPPPP----PLPGAGIPPPPPL-PG 1170
Query: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG----PDTSVSGPRL 872
A +P PPP P V +PP PP P + P PP PG P + G +
Sbjct: 1171 AGIP------PPPPLPGV------GIPPPPPL-PGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
Query: 873 TLALAPGPPPPPSRSPSSTL---SGPDLAGHSSSATSTPEELRGY 914
A AP PPP + P L SGP L S+T ++ G+
Sbjct: 1218 PPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
Score = 162 bits (410), Expect = 2e-39
Identities = 192/623 (30%), Positives = 226/623 (36%), Gaps = 120/623 (19%)
Query: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
SP + LT P P D P + P A QT +S + SP I
Sbjct: 747 SPTEEGGVLTLP------PVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISV---- 796
Query: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE--------------NL 538
L SH P +S PP S+ PP S++T N+
Sbjct: 797 -QLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNI 855
Query: 539 PSLAPPPLQTASAPLTTPHLE-TPPCPAPCP-LQAPPSPLTT---PPPETPSSIATPPPQ 593
PS PPPL + + P L PP P P P + P P T PPP + + PPP
Sbjct: 856 PS--PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP- 912
Query: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
PPL G PP PP L LPPL PP PPL A P P
Sbjct: 913 -------PPLPGAGIPP-----PPPLPGAGILPLPPLPGAGIPPP-PPLPGAAIPPPPPL 959
Query: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713
+ L PPP P P PP PP+ + PP P PP PP P A
Sbjct: 960 PGAGIPL------PPPLPGAGIP--PP--PPLPGAGIPPPPPLPGAGIPP--PPPLPGAG 1007
Query: 714 ---PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
PP P A PP PPPL P +PP PP + + PPP PPL P +PP
Sbjct: 1008 IPPPPPLPGAGIPP--PPPL--PGAGIPPPPP----LPGAGIPPP--PPL---PGAGIPP 1054
Query: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP----LAT 826
PP LP + + PPP + PP P P A P P P A +P P +
Sbjct: 1055 PPP--LPGAGIPPPPPLPGAGIPPPP----PLPGAGIPPPPPL-PGAGIPPPPPLPGVGI 1107
Query: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886
PPP PP+ A + P PP P P PP PG P + + P PP P +
Sbjct: 1108 PPP--PPLPGAGI----PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG 1161
Query: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG---GAAASPPPDAELAACHPAAWSRG 943
P P L G + P L G P G PPP A P
Sbjct: 1162 IPPP----PPLPG---AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP----- 1209
Query: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP-------ESATPAPGALDPGPS 996
PPL G P P P PP PG+ + GP S P P P
Sbjct: 1210 --PPLPGMGIP--PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265
Query: 997 PGTSGGKAAAGAGAGASSRSPKQ 1019
P SG G G S KQ
Sbjct: 1266 PLPSG---LFGLGMNQDKGSRKQ 1285
Score = 150 bits (379), Expect = 7e-36
Identities = 191/697 (27%), Positives = 241/697 (34%), Gaps = 157/697 (22%)
Query: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK-RSALSAG 159
ER PA +T G +G T G + + LR+ +E V + EA +++ +
Sbjct: 694 ERQYPALDTEVAS-GHQGLENGVTASGDVCLEALRLEEKE-VRHHRILEAKSIQTSPTEE 751
Query: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE---------GPRKSVS 210
T P G P G P P A P T+ PR+
Sbjct: 752 GGVLTLPPVDGLP---------------GRPPCPPGAESGPQTKFCSEISLIVSPRRISV 796
Query: 211 SASEHSTTE----PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA--RGTPR 264
H T+ P P SAG G +P S+ S +T + S+ + +
Sbjct: 797 QLDSHQPTQSISQPPPPPSLLWSAGQG--QPGSQPPHSISTEFQTSHEHSVSSAFKNSCN 854
Query: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP---SGTKARPVPPPD 321
P+ P P + ++ + PP P + + A P P GT+ P PPP
Sbjct: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP- 913
Query: 322 NAATPLP-ATLPPSPPL--ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP--P 376
PLP A +PP PPL A LPL PP P A +P PP P + PP P
Sbjct: 914 ----PLPGAGIPPPPPLPGAGILPL-PPLPGA-----GIPPPPPLPGAAIPPPPPLPGAG 963
Query: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
+ PP L P +P P PP P P
Sbjct: 964 IPLPPPL---PGAGIPPPPPLPGAGIPPPP---------------------------PLP 993
Query: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496
P P + P PPL +P PPL + P PL A
Sbjct: 994 GAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPG-------------A 1039
Query: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL-TTPPLENLPSLAPPPLQTASAPLTT 555
P PL +PP PP L P A + PPL PPPL A P
Sbjct: 1040 GIPPPPPLPGAGIPP--------PPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIP--- 1086
Query: 556 PHLETPPCPAPCPLQAPPSPL----TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611
PP P P PP PL PPP P + PPP P A PP PPL
Sbjct: 1087 -----PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP------PPL 1135
Query: 612 SPLATPPPQAPPXLALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
PPP P + +PP PP P P PPL P P + +
Sbjct: 1136 PGAGIPPPPPLPRVGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI--------- 1184
Query: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
PP PP+ PP PP+ + PP P + PP PP PP P PP
Sbjct: 1185 PPPPPLPGVGIPP-PPPLPGAGIPPPPPLPGMGIPPAPAPPLPP------PGTGIPP--- 1234
Query: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
PPL PP P + S P P+V L P
Sbjct: 1235 -----PPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266
Score = 143 bits (361), Expect = 8e-34
Identities = 142/494 (28%), Positives = 169/494 (34%), Gaps = 107/494 (21%)
Query: 294 PALGPLSSSPLATPSPSGTKARPVPPPDNAAT--PLPATLPPSPPLATPLPLAPPSPSAP 351
P+ PL + ++ P P PPP T LP+T P PP + PP P
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
P +P PP P + P P PP PP+ P PP P
Sbjct: 916 PG-AGIPPPPPLPGAGILPLPPLPGAGIPPP----PPL--------PGAAIPPPP----- 957
Query: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471
P P P + P PPL +P PPL
Sbjct: 958 ----------------------PLPGAGIPLPPPLPGAGIPPPPPLPG-AGIPPPPPLPG 994
Query: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL- 530
+ P PL A P PL +PP PP L P A +
Sbjct: 995 AGIPPPPPLPG-------------AGIPPPPPLPGAGIPP--------PPPL--PGAGIP 1031
Query: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL----TTPPPETPSS 586
PPL PPPL A P PP P P PP PL PPP P +
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIP--------PPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1083
Query: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP----PASPPL 642
PPP P A PP PPL + PPP P +PP PP P P PPL
Sbjct: 1084 GIPPPPPLPGAGIPPP------PPLPGVGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPL 1135
Query: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
P P + + PPP P A PP PP+ + PP P + P
Sbjct: 1136 PGAGIPPPPPLPRVGI--------PPPPPLPGAGIPPP--PPLPGAGIPPPPPLPGVGIP 1185
Query: 703 PLQVPPSP----PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
P PP P P PP+ + PPP P + PP PP PP + P P P
Sbjct: 1186 P--PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGP 1243
Query: 759 PLLAAPPLQVPPSP 772
PLL P+P
Sbjct: 1244 PLLPQVGSSTLPTP 1257
Score = 96.3 bits (238), Expect = 1e-19
Identities = 135/496 (27%), Positives = 165/496 (33%), Gaps = 107/496 (21%)
Query: 169 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
P PS A+ + GTE+ P P P A PP P + P P
Sbjct: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL---------PLP---- 935
Query: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
P G G+ P ++ P P P P A P P P + PP
Sbjct: 936 -PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA--GIPPP--- 989
Query: 287 PPRKDAA-PALGPLSSSPLATPSPSGTKARPVPPPDNAA-----TPLP-ATLPPSPPL-A 338
PP A P PL + + P P P PPP A PLP A +PP PPL
Sbjct: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
Query: 339 TPLPLAPPSPSA----PPSLQT--LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
+P PP P A PP L +P PP P + PP P PP +P + +P
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIP 1108
Query: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
P PP P P P P + P
Sbjct: 1109 PPPPLPGAGIPPPP---------------------------PLPGAGIPPPPPLPGAGIP 1141
Query: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
PPL + +P PPL + P PL A P PL + +PP
Sbjct: 1142 PPPPLPR-VGIPPPPPLPGAGIPPPPPLPG-------------AGIPPPPPLPGVGIPP- 1186
Query: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572
PP P + PP LP PP P P + PP PAP PL P
Sbjct: 1187 -------PP----PLPGVGIPPPPPLPGAGIPP------PPPLPGMGIPPAPAP-PL-PP 1227
Query: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP-PQAPPXLALPPLQ 631
P PPP P S PP L LP+P + PP P L + +
Sbjct: 1228 PGTGIPPPPLLPVS-------GPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDK 1280
Query: 632 APPSPPASP--PLSPL 645
P P P+ PL
Sbjct: 1281 GSRKQPIEPCRPMKPL 1296
Score = 86.3 bits (212), Expect = 2e-16
Identities = 125/440 (28%), Positives = 143/440 (32%), Gaps = 83/440 (18%)
Query: 12 AAARTPAARAPGLLTPRPP---GSPRPPPPVTPAA----LRVLGAAGAVGRKPLAERAGG 64
A + P + +L P PP G+ PPPP P A L L AG PL
Sbjct: 895 AIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP----- 949
Query: 65 IGGATIPESAPRAG-----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
GA IP P G P G P PP G G PP + P P
Sbjct: 950 --GAAIPPPPPLPGAGIPLPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLP 1004
Query: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
+G P PL G+ P AG P G P P
Sbjct: 1005 GAGIPPPPPLPGAGI---------------PPPPPLPGAGIPPPPPLPGAGIPPP----- 1044
Query: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
G + P P P A PP P + P P P G G+ P
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---------PPPP-----PLPGAGIPPPPP 1090
Query: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-PALGP 298
+ P P P P A P P P + PP PP A P P
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA--GIPPP---PPLPGAGIPPPPP 1145
Query: 299 LSSSPLATPSPSGTKARPVPPPDNAA-----TPLPAT-LPPSPPL-ATPLPLAPPSPSA- 350
L + P P P PPP A PLP +PP PPL +P PP P A
Sbjct: 1146 LPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAG 1205
Query: 351 ---PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH--SLTSPSLQA--- 402
PP L + PPA P PP PP PP L P +P S T P+ Q
Sbjct: 1206 IPPPPPLPGMGIPPAPAPPLPPPGTGIPP---PPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
Query: 403 --PPSPLALSSLQATTSLGS 420
PP P L L GS
Sbjct: 1263 LPPPLPSGLFGLGMNQDKGS 1282
Score = 48.9 bits (115), Expect = 3e-05
Identities = 97/332 (29%), Positives = 120/332 (36%), Gaps = 47/332 (14%)
Query: 637 PASPPLSPLATPSPQAPNALAVHLLQ---APFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
PA+PP + +P P A L LL P SP + S + P S +A P
Sbjct: 232 PAAPPTA--VSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
Query: 694 -QAPPSLAAPPLQVPPSPPASPPM---SPSAT--PPPQAPP--PLAAPPLQVPPSPPASP 745
Q PPS P+ PS PA+ P SPS+T P P+A P A P++
Sbjct: 290 PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEG 349
Query: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
P P AP +V P L P + Q P A P +LP PA
Sbjct: 350 EEDAFEDAPRGSPGEEWAP--EVGEDAPQRLGEEP--EEEAQGPDA---PAAASLPGSPA 402
Query: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865
P Q F P + + T Q L P P+ Q+PR P P
Sbjct: 403 --PSQRCFKPYPLITPCYIKTTTRQ---------LSSPNHSPSQSPNQSPRIKRRPEPSL 451
Query: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
S G R LA P + G AG S SA T EEL G + GG+
Sbjct: 452 S-RGSRTALASVAAP------AKKHRADGGLAAGLSRSADWT-EEL-GARTPRVGGS--- 499
Query: 926 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
A L A+ S G P A GAP
Sbjct: 500 ----AHLLERGVASDSGGGVSPALAAKASGAP 527
Score = 42.0 bits (97), Expect = 0.003
Identities = 83/324 (25%), Positives = 115/324 (35%), Gaps = 43/324 (13%)
Query: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPS-----PPASPPMSPSATPPPRVPPLLAAPPL 766
A P +P PQ L + PS P SP + + +P LAA P
Sbjct: 229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPR 288
Query: 767 --QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Q PPSP LP+S P P A +P A P FP P +A P+
Sbjct: 289 EPQQPPSP-GGLPVSEAPSLPAAQPAAKDSPSSTAFP-----FPEAGPGEEAAGAPVRGA 342
Query: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTL--QAPRRPPTPGPDTSVSGPRLTLALA-PGPP 881
+ + P +P + AP+R P+ GP A + PG P
Sbjct: 343 GDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEE-PEEEAQGPDAPAAASLPGSP 401
Query: 882 PPPSR--SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
P R P ++ +T +L S P + SP + +
Sbjct: 402 APSQRCFKPYPLIT-------PCYIKTTTRQL----SSPNHSPSQSPNQSPRIKRRPEPS 450
Query: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE-TEGPESATPAPGA----LDPG 994
SRG LA + AP A G G A GL + TE + TP G L+ G
Sbjct: 451 LSRGSRTALA---SVAAPAKKHRADG-GLAAGLSRSADWTEELGARTPRVGGSAHLLERG 506
Query: 995 PSPGTSGG----KAAAGAGAGASS 1014
+ + GG AA +GA A++
Sbjct: 507 VASDSGGGVSPALAAKASGAPAAA 530
Score = 40.0 bits (92), Expect = 0.012
Identities = 65/271 (23%), Positives = 94/271 (34%), Gaps = 37/271 (13%)
Query: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Q+ +R+ ++ + ++ GA + PT +P P G +GL
Sbjct: 200 QQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQP---------GAFLGLD 250
Query: 191 R-------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--------- 234
R A A P TE ++S E EP ++P + GGL
Sbjct: 251 RFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREP--QQPPSPGGLPVSEAPSLP 308
Query: 235 --QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Q A S SS+A P A G A G P A + + + A P ++
Sbjct: 309 AAQPAAKDSPSSTAFPFPE-AGPGEEAAGAPVRGAGDTDEEGEE-DAFEDAPRGSPGEEW 366
Query: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
AP +G + L + P AA LP + PS P PL P
Sbjct: 367 APEVGEDAPQRLGEEPEEEAQGPDAP----AAASLPGSPAPSQRCFKPYPLITPCYIKTT 422
Query: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383
+ Q S P PSQ+P + PSL
Sbjct: 423 TRQL--SSPNHSPSQSPNQSPRIKRRPEPSL 451
Score = 36.6 bits (83), Expect = 0.14
Identities = 53/201 (26%), Positives = 75/201 (37%), Gaps = 20/201 (9%)
Query: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
GSP + S L+ P A P +P S P P +AP SLPA+ P SP+ +
Sbjct: 265 GSPDTEQALSALSDLPESLAAEPREPQQPPS-PGGLPVSEAP-SLPAAQPAAKD-SPSST 321
Query: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL-EN 537
P + + AP+ E + + + P P + E+
Sbjct: 322 AFPFPE--------AGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGED 373
Query: 538 LPS-LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP--PPETPSSIATP---P 591
P L P + A P P PAP P PL TP T +++P P
Sbjct: 374 APQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSP 433
Query: 592 PQAPPALASPPLQGLPSPPLS 612
Q+P SP ++ P P LS
Sbjct: 434 SQSPN--QSPRIKRRPEPSLS 452
Score = 35.8 bits (81), Expect = 0.23
Identities = 54/205 (26%), Positives = 63/205 (30%), Gaps = 34/205 (16%)
Query: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
LQ P A PT +P+ G D + GP APG PD
Sbjct: 226 LQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG--------------SPDTEQ 271
Query: 900 HSSSATSTPEELRGYDSGPE-----GGAAASPPPDAELAACHPAAWSRGPAPPLAF-RGA 953
S+ + PE L P+ GG S P L A PAA + F
Sbjct: 272 ALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP--SLPAAQPAAKDSPSSTAFPFPEAG 329
Query: 954 PGAPLPWPPATGPGSAD--GLCTIYETE---------GPESATPAPGALDPGPSPGTSGG 1002
PG P G G D G +E PE AP L P G
Sbjct: 330 PGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
Query: 1003 KAAAGAGAGASSRSPKQARLGELPL 1027
A A A S +P Q PL
Sbjct: 390 DAPAAASL-PGSPAPSQRCFKPYPL 413
Score = 32.3 bits (72), Expect = 2.6
Identities = 47/185 (25%), Positives = 54/185 (29%), Gaps = 10/185 (5%)
Query: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
AP T A L P Q PPSP P E PS P P A SP
Sbjct: 263 APGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL----PAAQPAAKDSP 318
Query: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA---SPPLSPLATPSPQAPNALAV 658
P P P P A +P SP +P+
Sbjct: 319 SSTAFPFPEAGP--GEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQ 376
Query: 659 HLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
L + P P A S P SP P P P + SP SP S
Sbjct: 377 RLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS 436
Query: 718 PSATP 722
P+ +P
Sbjct: 437 PNQSP 441
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 173 bits (438), Expect = 9e-43
Identities = 252/900 (28%), Positives = 337/900 (37%), Gaps = 132/900 (14%)
Query: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
PTPG P P + S P P++RP P P +S S PSP
Sbjct: 1036 PTPG-PVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVL-PSPLG-- 1091
Query: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
G RP + +LS + TP AP S P G +L P
Sbjct: 1092 ---VLSGTSRPPTPTLS---------------LKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133
Query: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA--ATPLPATLPPSPPLA------ 338
PP PA +S+ AT + + A P P P + + A LP ++
Sbjct: 1134 PPGYTFPPAAATTTSTTTATATTTAVPA-PTPAPQRLILSPDMQARLPSGEVVSIGQLAS 1192
Query: 339 -TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP------------------MQA 379
P+A S P + Q + +Q P + +
Sbjct: 1193 LAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLIS 1252
Query: 380 PPS----LQTIPPIQVPHS---LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
P+ +Q + P P L S + P+P LS A + PT+ + +
Sbjct: 1253 QPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQV-PPTMVNNTGVVKI 1311
Query: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT------SLSPAVSPLSSPLTI 486
RQ +P P + P P P L P L +L A +P+ +P +
Sbjct: 1312 VVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV 1371
Query: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
PL L + S SP+ S+ PL S L PS PAS + P+ N LA P
Sbjct: 1372 RPL--LKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPAS-SPMPIPNSSPLASPVS 1428
Query: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606
T S PL++ + P P L AP S T P P +++ + P L
Sbjct: 1429 STVSVPLSS----SLPISVPTTLPAPASAPLTIPISAPLTVSA---------SGPALLTS 1475
Query: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPA-------SPPLSPLATPSPQ---APNAL 656
+PPL+P+ P AP +L P A PS A +P LS TP AP +
Sbjct: 1476 VTPPLAPVV---PAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSS 1532
Query: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716
V L + +P SP V P S ASP PSA P+ A SL AP S + P+
Sbjct: 1533 HVPGLNSTVAPACSP-VLVPASALASP--FPSAPNPAPAQASLLAPASSA--SQALATPL 1587
Query: 717 SPSATPPPQAPPPLAAPPLQ----VPPSPPASPPMSPSATPPPRVPP-------LLAAPP 765
+P A P P APPL + PSP A+P ++ S TP P + P L +A P
Sbjct: 1588 APMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASP 1647
Query: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPL 824
VP P P S P P L +P Q L PA P SPS +L L
Sbjct: 1648 --VPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTL---SL 1702
Query: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884
T PQ P L + P+ PT A PGP GP TL+LAP PP P
Sbjct: 1703 GTGNPQGP--FPTQTLSLTPASSLVPT-PAQTLSLAPGPPL---GPTQTLSLAPAPPLAP 1756
Query: 885 SR----SPSSTLSGPDLAGHSSSAT-STPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
+ +P+ TL+ LA SSSA+ P ++ P P LA +
Sbjct: 1757 ASPVGPAPAHTLT---LAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813
Query: 940 WS-RGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDPGPSP 997
S A L + APLP + P S D T+ GP S P+ GP P
Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPS-PPSTATSFGGPRP 1872
Score = 142 bits (359), Expect = 1e-33
Identities = 208/783 (26%), Positives = 287/783 (36%), Gaps = 158/783 (20%)
Query: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324
AP P +PKP ++ R Q P ++ + +PL P P RP P P+ +A
Sbjct: 980 APDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLG-PVP----VRPPPGPELSA 1034
Query: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
P P P P P+ + + PA PP P PP
Sbjct: 1035 QPTPG----------------PVPQVLPASLMVSASPAGPP--------LIPASRPPGPV 1070
Query: 385 TIPPIQVPHSLTSPS-LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS 443
+PP+Q P+S + P L +P L+ +S T +L L+ +P +SL
Sbjct: 1071 LLPPLQ-PNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLL- 1128
Query: 444 PSRPASTPPDS--PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP-LQALSSLASHSP 500
+P + PP PP A + + T+ PA +P L + P +QA
Sbjct: 1129 --KPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVS 1186
Query: 501 QAPLSSLIMPPLETQSSLAPPSLQTP--PASLTTPPLENLPSLAPPPLQTASAPLTTP-- 556
L+SL P+ P + Q +LT + L P PLQ L +
Sbjct: 1187 IGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGG 1246
Query: 557 --HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
HL + P P+P TP PSS +P
Sbjct: 1247 QHHLISQPAHVALIQAVAPTPGPTPVSVLPSS-------------------------TPS 1281
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
TP AP L+LP L+ P N V ++ PV
Sbjct: 1282 TTP---APTGLSLP-------------LAANQVPPTMVNNTGVVKIVVRQAPRDGLTPV- 1324
Query: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
PP++P+ PPS P++ P + P +P + + P P P L P
Sbjct: 1325 --------PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPT--PTLVRPL 1374
Query: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS--PPASLPMSPLAKPPPQAPPAL 792
L++ SP SP +S SA P PL + PL VP S PAS PM P+ P A P
Sbjct: 1375 LKLVHSP--SPEVSASA---PGAAPLTISSPLHVPSSLPGPASSPM-PIPNSSPLASPVS 1428
Query: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVPPSPPASP 850
+T + S P S P P SA L T P AP ++A P L +PP +P
Sbjct: 1429 STVSVPLSSSLPISVPTTLPAPASAPL------TIPISAPLTVSASGPALLTSVTPPLAP 1482
Query: 851 TLQAPRRPPTPGPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 909
+ A PP+ P S S LTL LA P +LS GH T
Sbjct: 1483 VVPAAPGPPSLAPSGASPSASALTLGLATAP----------SLSSSQTPGHPLLLAPTSS 1532
Query: 910 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP----------------APPLAFRGA 953
+ G +S + P + LA+ P+A + P A PLA A
Sbjct: 1533 HVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAA 1592
Query: 954 PG----APLPWPP-------ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 1002
P AP P PP A PG+A L + S TP P + P +PGTS
Sbjct: 1593 PQTAILAPSPAPPLAPLPVLAPSPGAAPVLAS--------SQTPVP-VMAPSSTPGTSLA 1643
Query: 1003 KAA 1005
A+
Sbjct: 1644 SAS 1646
Score = 129 bits (324), Expect = 2e-29
Identities = 218/769 (28%), Positives = 299/769 (38%), Gaps = 142/769 (18%)
Query: 13 AARTPAARAPGLLTPRPPGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
A R P++ P +L PRP +P R P P A + V +PL + +
Sbjct: 1330 APRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV--RPLLKLVHS-PSPEVS 1386
Query: 72 ESAPRAGPTRSAG-----TSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRAS-GTT 124
SAP A P + +S PAS P P A P +T P+SS S TT
Sbjct: 1387 ASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTT 1446
Query: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAA 183
P P AP +SA SGP T +P +A
Sbjct: 1447 LPAP-------------------ASAPLTIPISAPLTVSASGPALLTSVTPPLA------ 1481
Query: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASR 240
P A P PP+ P + SAS + T PS ++ + P L +S
Sbjct: 1482 --------PVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSH 1533
Query: 241 --SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
L+S+ P SP SA +P PS P P Q A L P
Sbjct: 1534 VPGLNSTVAPACSPVLVPASALASP----FPSAPNPAPAQ--------------ASLLAP 1575
Query: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358
SS+ A +P A P A P+ P+PPLA PLP+ PSP A P L +
Sbjct: 1576 ASSASQALATPLAPMAAP-----QTAILAPS---PAPPLA-PLPVLAPSPGAAPVLASSQ 1626
Query: 359 SP---------PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
+P P T + A P P+ AP S QT+ P VP L SP A LAL
Sbjct: 1627 TPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSP---ASTQTLAL 1683
Query: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469
+ A T LG + T S T +P+ + T PAS+ +P LSL PPL
Sbjct: 1684 APALAPT-LGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTP--AQTLSLAPGPPL 1740
Query: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS-LAPPSLQTPPA 528
+ + +++P + PL + AS AP +L + P + +S LAP S+QT
Sbjct: 1741 GPTQTLSLAP-APPL---------APASPVGPAPAHTLTLAPASSSASLLAPASVQT--- 1787
Query: 529 SLTTPPLENLPSLAPPPLQT-ASAPLTTPH--------LETPPCPAPCPL-QAPPSPLTT 578
LT P +P+L P QT A AP +T + + AP P+ P++
Sbjct: 1788 -LTLSPAP-VPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSK 1845
Query: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
P+T + + PP +PP+ A+ G P P P PPP++P L L+
Sbjct: 1846 DEPDTLTLRSGPP--SPPSTATS--FGGPRPRRQP--PPPPRSP--FYLDSLEEKRKRQR 1897
Query: 639 SPPLSPLATPSPQAPNALA-VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
S L + S +A ALA V+ + PV +P P + P P+ ++A
Sbjct: 1898 SERLERIFQLS-EAHGALAPVYGTEVLDFCTLPQPVASPIGPRSPGPSHPTFWTYTEAAH 1956
Query: 698 SLAAPPLQ--------------VPPSPPASPPMSPSATPPPQAPPPLAA 732
P Q V P A PP + PPP P AA
Sbjct: 1957 RAVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPRQAA 2005
Score = 115 bits (287), Expect = 3e-25
Identities = 190/741 (25%), Positives = 264/741 (35%), Gaps = 137/741 (18%)
Query: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
L + + P PP P M M P Q + V ++ +P P P L
Sbjct: 974 LLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELS 1033
Query: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
A + G P Q + L +S SP+ P P PP P+ LP P SL
Sbjct: 1034 AQPTPG-PVPQVLPASLMVS--------ASPAGPPLIPASRPP--GPVLLPPLQPNSGSL 1082
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
P V P PL LS S P LS PP + S APP P +S
Sbjct: 1083 -PQVLP-------SPLGVLSG-TSRPPTPTLSLKPTPPAPVRLSPAPP----PGSSSLLK 1129
Query: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET--PSSIATPP 591
PL P PP + TT T PAP P AP + +P + PS
Sbjct: 1130 PLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTP--APQRLILSPDMQARLPSGEVVSI 1187
Query: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
Q P S PL+ +Q + LA P+
Sbjct: 1188 GQLASLAQRPVANAGGSKPLTF---------------QIQGNKLTLTGAQVRQLAVGQPR 1232
Query: 652 APNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPP 703
VHL+ A P +QA P PVS PS+TP + P+ + P
Sbjct: 1233 PLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLP 1292
Query: 704 L---QVPPSPPAS-------------------PPMSPSATPPPQAPPPLAAPPLQVPPSP 741
L QVPP+ + PP++P+ PP P + P + P
Sbjct: 1293 LAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGR 1352
Query: 742 PASPPMSPSATPPPR---VPPLLA---APPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
+P + + P P V PLL +P +V S P + P++ P P +L P
Sbjct: 1353 LPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLT--ISSPLHVPSSLPGP 1410
Query: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
+P P +S P +P S + S+P+S + P+ L P S P + + AP
Sbjct: 1411 ASSPMPIPNSS-PLASPVSSTVSVPLS-------SSLPISVPTTLPAPASAPLTIPISAP 1462
Query: 856 RRPPTPGPD--TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913
GP TSV+ P + P P PPS +PS A S+SA +
Sbjct: 1463 LTVSASGPALLTSVTPP--LAPVVPAAPGPPSLAPSG-------ASPSASALTL------ 1507
Query: 914 YDSGPEGGAAASPPPDAELAACHPA--AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971
G A +P + HP A + P L AP P P SA
Sbjct: 1508 -------GLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACS----PVLVPASA-- 1554
Query: 972 LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ 1031
A+P P A +P P+ + A++ + A A+ +P A P A+
Sbjct: 1555 -----------LASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAA-----PQTAIL 1598
Query: 1032 ASVVQHLLSRTLLLAAAEGAA 1052
A L+ +LA + GAA
Sbjct: 1599 APSPAPPLAPLPVLAPSPGAA 1619
Score = 110 bits (275), Expect = 7e-24
Identities = 212/924 (22%), Positives = 301/924 (32%), Gaps = 220/924 (23%)
Query: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
P+ EGP A + S+ RR +RP +R + L
Sbjct: 2357 PQEEEEGP-----GAGDESSCGTGGGTHRRSKKAKAPERPGTRV----SERLRGARAETQ 2407
Query: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317
A TP AH ++ PP+ +P R+ + P+P RP
Sbjct: 2408 GANHTPVISAHQTR------STTTPPRCSPARER------------VPRPAP-----RPR 2444
Query: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377
P P +A +PA +P P++ P+P++ P+P + LPSPP PPSQ PP + P
Sbjct: 2445 PTPASAPAAIPALVPV--PVSAPVPISAPNPITILPVHILPSPP--PPSQIPPCSS--PA 2498
Query: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437
PP T PP P PP+
Sbjct: 2499 CTPPPACTPPPAHTP----------PPA-------------------------------- 2516
Query: 438 QASLTSPSRPASTPPDSPPLQAP---LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Q L +PS P P S P+ A L L P + SP S L SS
Sbjct: 2517 QTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSS 2576
Query: 495 LASHSPQ--APLSSLIMPPLETQSSLAP--PSLQTPPASLTTPPLENLPSLAPPPLQTA- 549
L+ P+ P++ I+P E SL P PSL S+ + P A T
Sbjct: 2577 LSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVL 2636
Query: 550 ----SAPLTTPH---LETPPCPAPC-PLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
PL LE PP A PLQ P T T + T P+ P L +
Sbjct: 2637 PEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTA 2696
Query: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP----------PASPPLSPLATPSP- 650
+ +P S AT P+ P A PP + + P PP + P
Sbjct: 2697 EVA---APSTSSSATSSPEGPSP-ARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPG 2752
Query: 651 ------------------QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV------S 686
+ + V + + P SP V++ P +SPP+ +
Sbjct: 2753 RLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAA 2812
Query: 687 PSA---TPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT---PPPQAPPPLAAPPLQ--VP 738
PS+ TPP Q P +A +++ + SP A PP PP + P
Sbjct: 2813 PSSSLPTPPQQ--PFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSP 2870
Query: 739 PSPPASPPMSPSAT---------PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789
+PS+T P P L+ A P+ P P P+ P +P +
Sbjct: 2871 ADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGP--QPVHRPN 2928
Query: 790 PALATPPLQALPSPPAS--FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP--- 844
P L+ + PP + P S + PPP P+ P L V P
Sbjct: 2929 PLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTAT 2988
Query: 845 ------------SPPASPTLQAPRRPPTPGP------DTSVSGPRLTLALAPGPPP---- 882
SPP + P+ PP+P P D + + L P
Sbjct: 2989 VANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQG 3048
Query: 883 -------------PPSRSPSSTLSGPDLAGHSSSATST----PEELRGYDSGPEG----- 920
P +R L + G S + ++L DSGP G
Sbjct: 3049 ESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTP 3108
Query: 921 ---------------GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965
+ PP + E A G +P LA RG P P P
Sbjct: 3109 PVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGS 3168
Query: 966 PGSADGLCTIYETEGPESATPAPG 989
++ + E EG + PG
Sbjct: 3169 VEESEAEASGEEEEGDGTPRRRPG 3192
Score = 90.5 bits (223), Expect = 8e-18
Identities = 113/380 (29%), Positives = 146/380 (38%), Gaps = 54/380 (14%)
Query: 666 SPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP----ASPPMSPSA 720
+P P P P AP + PA PV SA P AP + P+ + PSPP P SP+
Sbjct: 2440 APRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPAC 2499
Query: 721 TPPPQ-APPPLAAPP-----LQVPPSP----PASPPMSPSATPPP---RVPPLLAAPPLQ 767
TPPP PPP PP L P SP P S P+S S T P R L A L
Sbjct: 2500 TPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALA 2559
Query: 768 VPPS----PPASLPMSPLAKPPPQ--APPALATPP-----LQALPSPPA------SFP-G 809
P S AS S L+ PP+ P A+ P L PS P+ S P G
Sbjct: 2560 SPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNG 2619
Query: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPL--LQVPPSPPASPTLQAPRRPPTPGPD--- 864
Q +P ++ + P + P+ + L++PPS + LQ P +
Sbjct: 2620 QEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTE 2679
Query: 865 --TSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATSTPEELRGYDSG--- 917
T S P L PS S S+T S GP A TS E+RG +G
Sbjct: 2680 AKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPG 2739
Query: 918 -PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 976
P G P + R RGA +P T ++ G ++
Sbjct: 2740 QPPGPKVLRKLPGRLVTVVEEKELVRRRRQQ---RGAASTLVPGVSET--SASPGSPSVR 2794
Query: 977 ETEGPESATPAPGALDPGPS 996
GPES+ P G + PS
Sbjct: 2795 SMSGPESSPPIGGPCEAAPS 2814
Score = 89.0 bits (219), Expect = 2e-17
Identities = 166/705 (23%), Positives = 242/705 (34%), Gaps = 120/705 (17%)
Query: 102 RAPPAKNTSPGP--VSSPGRASGTTRPGPLGQK----GLRISAEETVARGKATEAPKRSA 155
R P + PG SS G GT R + G R+S AR + A
Sbjct: 2355 RLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPV 2414
Query: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215
+SA R T+ TP SPA R +PRPAP RPRP ++ +
Sbjct: 2415 ISAHQTRSTT--TPPRCSPARER----------VPRPAP--RPRPTPASAPAAIPALVPV 2460
Query: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-- 273
+ P P + P + S S P SSPA + P A P PAH P
Sbjct: 2461 PVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPP--PAHTPPPAQT 2518
Query: 274 ----PKGLQALRPPQVT-------------PPRKDAAPALGPLSSSPLATPSPSGTKARP 316
P L PP V P + A AL S LA+ + S T +
Sbjct: 2519 CLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLS 2578
Query: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS--PPATPPSQAPPSMTT 374
+ PP + LP + P L L P +PS ++P+ P S ++T
Sbjct: 2579 LVPPKDL---LPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTV 2635
Query: 375 PP--------------MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
P ++ PPS + P+Q P S + + SS + L +
Sbjct: 2636 LPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVT 2695
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL-------PASPPLQTSL 473
+ A P + ++ +SP P+ P A + + P PP
Sbjct: 2696 AEVAA--------PSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPP----- 2742
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL-ETQSSLAPPSLQTPPASLTT 532
P V + ++ + Q +S ++P + ET +S PS+++ ++
Sbjct: 2743 GPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESS 2802
Query: 533 PPL----ENLPS--LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
PP+ E PS L PP Q A H+E P + L PP
Sbjct: 2803 PPIGGPCEAAPSSSLPTPPQQPFIA---RRHIELGVTGGGSPENGDGALLAITPPAVKRR 2859
Query: 587 IATPPPQ-APPALASPPLQGLPSPPLSPL---ATPPPQAPPXLALPPLQAPPSPPASPPL 642
PP + PA A + PS L A P P + P+ P P PL
Sbjct: 2860 RGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPL 2919
Query: 643 SP--LATPSP-----------QAPNALAVHL-----------LQAPFSPPPSPPVQAPFS 678
P + P+P + P A + + ++ PPP P P
Sbjct: 2920 GPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLP 2979
Query: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM-SPSATP 722
P P + A + S +PP + PP +PP PS P
Sbjct: 2980 PLLVCPTATVANTVTTVTIS-TSPPKRKRGRPPKNPPSPRPSQLP 3023
Score = 85.9 bits (211), Expect = 2e-16
Identities = 117/455 (25%), Positives = 170/455 (37%), Gaps = 82/455 (18%)
Query: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATPPP-QAPPPL 730
A +P S + S T P + P+ P P P+P ++P P+ P P AP P+
Sbjct: 2409 ANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPI 2468
Query: 731 AAP------PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL--PMSPLA 782
+AP P+ + PSPP + P ++P PP PP PP L P SPL
Sbjct: 2469 SAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLL 2528
Query: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPS-------ASLPMSPLATPPPQAPPVL 835
PP P + + L P A QA SP AS S L+ PP+ +
Sbjct: 2529 LGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPV 2588
Query: 836 AAPLLQV-------PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP---------- 878
A +L V PS P S TL+A P + S TL + P
Sbjct: 2589 AVEILPVSEKNLSLTPSAP-SLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVS 2647
Query: 879 ---GPPPPPSRSPSSTLSGPDLAGHSS-------SATSTPEE----LRGYDSGPEGGAAA 924
G PPS + L P A +S + TS+PE+ + + P ++A
Sbjct: 2648 ESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSA 2707
Query: 925 SPPPDAELAACHPAAWSRGPAPPLAFR----GAPGAPLPWPPATG--PGSADGLCTIYE- 977
+ P+ A P R + + R G PG P P P PG L T+ E
Sbjct: 2708 TSSPEGPSPARPP---RRRTSADVEIRGQGTGRPGQP-PGPKVLRKLPGR---LVTVVEE 2760
Query: 978 --------TEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029
+ ++T PG + SPG+ ++ +G + P +A P +
Sbjct: 2761 KELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEA----APSSS 2816
Query: 1030 LQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEG 1064
L Q ++R + G GG P +G
Sbjct: 2817 LPTPPQQPFIARRHIELGVTG-----GGSPENGDG 2846
Score = 79.0 bits (193), Expect = 2e-14
Identities = 152/624 (24%), Positives = 223/624 (35%), Gaps = 123/624 (19%)
Query: 35 PPPPVTPAALRVLGAAGAVGRKPLAERAGG----IGGATIPESAPRAGPTRSAGTSSRNP 90
PP + P A+ +L V K L+ + +IP + P + GT+
Sbjct: 2581 PPKDLLPVAVEIL----PVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLT-- 2634
Query: 91 ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150
GE P + S G P AS PL + R S E T A+ +
Sbjct: 2635 -----VLPEGEELPLCVSESNGLELPPSAASDEPLQEPL--EADRTSEELTEAKTPTSSP 2687
Query: 151 PKRSAL-----SAGARRDTSGPTPGTPSPAMA-RRSRAAGTEV---GLPRPAPSARPRPP 201
K L +A + ++ +P PSPA RR +A E+ G RP P+
Sbjct: 2688 EKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVL 2747
Query: 202 TEGPRKSVSSASEHSTT-----EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256
+ P + V+ E + A+ P P S S+ S + P SSP G
Sbjct: 2748 RKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGG 2807
Query: 257 P-SARGTPRAPAHPSQP---------------KPKG----LQALRPPQVT-----PPRKD 291
P A + P P QP P+ L A+ PP V PP+K+
Sbjct: 2808 PCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKN 2867
Query: 292 AAPALGP--LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349
+PA + +P +T A PVP P+ TL + P+ P + P P
Sbjct: 2868 RSPADAGRGVDEAPSSTLKGKTNGADPVPGPE--------TLIVADPVLEPQLIPGPQPL 2919
Query: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS-------LQA 402
P + P+P +P + PP + +P +P +++S Q
Sbjct: 2920 GPQPVHR-PNPLLSPVEKRRRGR-------PPKARDLP---IPGTISSAGDGNSESRTQP 2968
Query: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
PP P L+ L + T+ T + +T+S + P R PP +PP P
Sbjct: 2969 PPHPSPLTPLPPLLVCPTATVANTVTTVTIST-------SPPKRKRGRPPKNPPSPRPSQ 3021
Query: 463 LPASPPLQTSL--------------------SPAVSPLSSPLTIHP---LQALSSLASHS 499
LP TS+ S + S PLT L+A S
Sbjct: 3022 LPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKS 3081
Query: 500 PQAPLSSLIMPPLETQSSLAPPSLQ-TPPASLTTPPLENL---PSLAPPPLQTASAP--- 552
+ + ++I L+ S P L+ TPP TP L + P PPL+T P
Sbjct: 3082 GGSMVVAVIQDDLDLADS-GPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKR 3140
Query: 553 LTTPHLETPPCPAPCPLQAPPSPL 576
P +P LQ PPSPL
Sbjct: 3141 AGAPVGGSPGLAKRGRLQ-PPSPL 3163
Score = 77.8 bits (190), Expect = 5e-14
Identities = 189/784 (24%), Positives = 266/784 (33%), Gaps = 127/784 (16%)
Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL-AERAGGIGGATIPESAPRAG--PTRSA 83
PRP PRP P PAA+ L P+ A I I S P P S+
Sbjct: 2437 PRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSS 2496
Query: 84 GTSSRNPASRPPASGRGERAPPAKN-----TSP---GPVSSPGRASGTTRPGPLGQKGLR 135
+ PA PP + PPA+ +SP GP S P AS T P GLR
Sbjct: 2497 PACTPPPACTPPPA---HTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLP-----LGLR 2548
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---PAMARRSRAAGTEVGLPRP 192
AE +A +P+ L++ A +TS + P P + + L
Sbjct: 2549 PEAE---LCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS 2605
Query: 193 APSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSAT 247
APS + G + ++E +T P P S GL+ P S ++S
Sbjct: 2606 APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPS---AASDE 2662
Query: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
PL P + ++ A S P+ PQ + AAP S+S AT
Sbjct: 2663 PLQEPLEADRTSEELTEAKTPTSSPE--------KPQELVTAEVAAP-----STSSSATS 2709
Query: 308 SPSG-TKARPVPPPDNAATPLPAT------LPPSPPLATPLP-----------LAPPSPS 349
SP G + ARP +A + PP P + LP L
Sbjct: 2710 SPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQ 2769
Query: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP-HSLTSPSLQAPPSP-- 406
+ TL P + S +P S + M P ++ PPI P + S SL PP
Sbjct: 2770 QRGAASTL-VPGVSETSASPGSPSVRSMSGP---ESSPPIGGPCEAAPSSSLPTPPQQPF 2825
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD------------- 453
+A ++ + G + L ++P + P + +P D
Sbjct: 2826 IARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTL 2885
Query: 454 ------SPPLQAPLSL-PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
+ P+ P +L A P L+ L P PL P LS + P +
Sbjct: 2886 KGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKA 2945
Query: 507 LIMPPLETQSSLAPPSLQTPPASLTTP-PLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565
+P T SS + ++ P PL LP L P T + +TT + T
Sbjct: 2946 RDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTIST----- 3000
Query: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
+PP PP+ P S P P P L L S L P Q
Sbjct: 3001 -----SPPKRKRGRPPKNPPS---PRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESE- 3051
Query: 626 ALPPLQAPPSPPASPPLSPLATPSPQAP--------NALAVHLLQAPFSPPPSPPVQAPF 677
+ S PL+ LA +A ++ V ++Q S P
Sbjct: 3052 -----GSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLEL 3106
Query: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
+PP ++P P SL PPL+ P A P P LA
Sbjct: 3107 TPPV-VSLTPKLRSTRLRPGSL-VPPLETEKLP------RKRAGAPVGGSPGLAKRGRLQ 3158
Query: 738 PPSP 741
PPSP
Sbjct: 3159 PPSP 3162
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 172 bits (437), Expect = 1e-42
Identities = 221/790 (27%), Positives = 298/790 (37%), Gaps = 137/790 (17%)
Query: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAH---------PSQPKPKGLQALRPPQVTPP 288
A + + + TP P P +P PA P QPKP G+ + Q+TP
Sbjct: 310 AGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPK 369
Query: 289 RKDAAPALGPLSSSPLATPS-----------PSGTKARPVPPPDNAATPLPATLPPSPPL 337
A A + P A P +G + V A L A + PP
Sbjct: 370 PFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPP- 428
Query: 338 ATPLPLAPPSP----SAPPSLQTL--PSPPATPPSQAPPSMT------TPPMQAPPSLQT 385
AT APP P S P S+ L S P P P +Q P L
Sbjct: 429 ATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSA 488
Query: 386 IP--------PIQVPHS----LTSPSL--QAPPSPLALSSLQATTS-------LGSPTLQ 424
+P PH+ + +P L Q PL+L + A S L + +Q
Sbjct: 489 LPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQ 548
Query: 425 ATHSFLTMSPRQTQA-SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483
L P A SL + S+PA P + + ++LP S + + ++P
Sbjct: 549 VGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATP 608
Query: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLA--PPSLQTP----PASLTTP-PLE 536
A +PQAP + PL Q A PP TP P TTP P
Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP 668
Query: 537 NLPS------LAPPPLQTASAPLTTPHLE--TPPCPAPCPLQAPPSPLTTPPPETPSSIA 588
L S L PP T +A LT L+ P + PL A L+ P ++
Sbjct: 669 GLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP---ASVIVS 725
Query: 589 TPPPQAPPALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646
PPP PA A+P +G P +P A+P P AP A PL+ P P+S P P
Sbjct: 726 APPPAQDPAPATPVAKGAGLGPQAPDSQASPAP-APQIPAAAPLKGP--GPSSSPSLPHQ 782
Query: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS-------- 698
P +P+ + H + P PP P Q+ PP+ PP+ P PP QAPP+
Sbjct: 783 APLGDSPHLPSPHPTRPPSRPPSRP--QSVSRPPSEPPLHP--CPPPQAPPTLPGIFVIQ 838
Query: 699 --LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
L PP P+P A P P P Q P P +PPS +S S S T
Sbjct: 839 NQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRL 898
Query: 757 VPPL-----LAAPPLQVP---PSPPASLPMSPLAKPPPQAPP---ALATPPLQALPSPPA 805
P L PP Q P P+PP +L + P PP PP + T P ALP P A
Sbjct: 899 PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKA 958
Query: 806 ---------------SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
+ G AP +P S + PL +P AA +L +P +P
Sbjct: 959 LLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP--------AASVLVSGQAPSGTP 1010
Query: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
T AP P P P + P L P +++ +S L ++A +SS P
Sbjct: 1011 T--APSHAPAPAPMAATGLPPLL--------PAENKAFASNLPTLNVAKAASSGPGKPSG 1060
Query: 911 LRGYDSGPEG 920
L+ Y+S G
Sbjct: 1061 LQ-YESKLSG 1069
Score = 162 bits (409), Expect = 2e-39
Identities = 224/795 (28%), Positives = 279/795 (35%), Gaps = 121/795 (15%)
Query: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA-TLPPS 334
G A P TP + A A G L SSPL P+P+ R P P PA LPP
Sbjct: 309 GAGAASAPTGTPSGQPLAVAPG-LGSSPLV-PAPNVILHRTPTP----IQPKPAGVLPPK 362
Query: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA-------------PP 381
TP P AP + T+ P P Q M A P
Sbjct: 363 LYQLTPKPFAPAGATL-----TIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAP 417
Query: 382 SLQTIPPIQVPHSLTSPSLQAPPS----PLALSSLQATTSLGSPT---LQATHSFLTMSP 434
+LQ Q P + T + PP P+++ L +S+ P L + FL
Sbjct: 418 ALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477
Query: 435 RQTQASLTSPSRPASTPPDSPPLQAPLS---LPASPPLQT-------SLSPAVSPLSSPL 484
Q + PA+ AP + L A+P L SL P ++P S
Sbjct: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAH 537
Query: 485 TIHPLQALSSLASHSP--QAPLSSLIMPPLETQSSLAP--PSLQTPPASLTTPP-----L 535
+ H L A Q P+S L L TQS AP P+ T +T PP L
Sbjct: 538 SAHILSAAPIQVGQPALFQMPVS-LAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAML 596
Query: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET--PSSIATPPPQ 593
L P A+ P L P P P + P PL P+ P TP
Sbjct: 597 NTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA 656
Query: 594 APPALASP-PLQGLPSPPLSPLATPPPQAPPXLAL----------------------PPL 630
APP +P P GL S P + PP A P L P L
Sbjct: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
Query: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPP-PSPPVQAPFSPPASPPVSPS 688
P S S P P P+P P A L QAP S P+P Q P + P P PS
Sbjct: 717 SVPASVIVSAP-PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP-GPS 774
Query: 689 ATP--PSQAP----PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742
++P P QAP P L +P PPS P S P S S PP PP PP Q PP+ P
Sbjct: 775 SSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSR--PPSEPPLHPCPPPQAPPTLP 832
Query: 743 ASPPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
+ PPP P AP PP P S P P P PP+ + + +
Sbjct: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892
Query: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
+ P P L PP Q P + P PP + P PP P
Sbjct: 893 ETSSRLPAPTPSD-------FQLQFPPSQGPH-------KSPTPPPTLHLVPEPAAPPPP 938
Query: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTL----SGPDLAGHSSSATSTPEELRGYDSG 917
P T + P P P ++ SG L + A + P+ G
Sbjct: 939 PPRT------FQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLG 990
Query: 918 PEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIY 976
P AAS + + P A S PAP P+A G P P PA A L T+
Sbjct: 991 PLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLP----PLLPAENKAFASNLPTLN 1046
Query: 977 ETEGPESATPAPGAL 991
+ S P L
Sbjct: 1047 VAKAASSGPGKPSGL 1061
Score = 123 bits (309), Expect = 9e-28
Identities = 206/768 (26%), Positives = 279/768 (36%), Gaps = 134/768 (17%)
Query: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP--SPLALSS--LQATTS 417
A P + P S +Q PP++ T + P + + +L P P+ L + LQ
Sbjct: 154 AGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPG 213
Query: 418 L-----GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472
L GSP AT + L ++P Q + P +TP L P+
Sbjct: 214 LQGLPNGSPG-GATAATLGLAPIQV---VGQPVMALNTPTSQ-------LLAKQVPVSGY 262
Query: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
L+ A P S P+T+ A Q LS+ + L S + P +
Sbjct: 263 LASAAGP-SEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPS 321
Query: 533 -PPLENLPSLAPPPLQTASAPLTTPH-LETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
PL P L PL AP H TP P P + P TP P P+
Sbjct: 322 GQPLAVAPGLGSSPL--VPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLT 379
Query: 591 PPQAPPALASPP-------------------LQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
P AL P L G P+P L P A A
Sbjct: 380 IQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA----- 434
Query: 632 APPSPPA--SPPLSPLATPSPQAPNALAVHLL--QAPFSPPPSPPVQAPFSPPASPP--- 684
APP PP S P+S + A H+L Q F P +P VQ P A P
Sbjct: 435 APPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVG 494
Query: 685 --VSPSATP---------PSQAPPSLAAPPLQVPPSPPASPPMSP---SATPPP------ 724
+ +A P P +LA P P P S S SA P
Sbjct: 495 GQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
Query: 725 -QAPPPLAAP--PLQVPPSP--PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-- 777
Q P LAA P Q P+P PA+ + T PP +L P V P+ PA+
Sbjct: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
Query: 778 MSPL--AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
+P+ +P PQAPPA++TP L P A P QAP +P A+ P P AT P +P +
Sbjct: 615 AAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAP-TPQAAAP--PQATTPQPSPGLA 671
Query: 836 AAPLLQVPPSPP-ASPT-------LQAPRRPPTPGPDTSVSGPRLTL---ALAPGPPPPP 884
++P V PP A+PT LQ S GP L++ + PPP
Sbjct: 672 SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
Query: 885 SRSPSSTLS-----GPDLAGHSSSATSTPEELRGYD-SGPEGGAAASPPPDAELA----- 933
+P++ ++ GP +S P+ GP ++ S P A L
Sbjct: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHL 791
Query: 934 -ACHPAAW-SRGPAPPLAFRGAPGAPL--PWPPATGPGSADGLCTIYETEG--PESATPA 987
+ HP SR P+ P + P P P PP P + G+ I G P ++ PA
Sbjct: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
Query: 988 P------------------GALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
P G L P P S +A + + SSR P
Sbjct: 852 PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP 899
Score = 117 bits (294), Expect = 5e-26
Identities = 245/1038 (23%), Positives = 340/1038 (32%), Gaps = 212/1038 (20%)
Query: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVT--------PAALRVLGAA-GAVGRKPLAERA 62
A + P + A G L + +P P T P+A+ +L G V A
Sbjct: 553 ALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT 612
Query: 63 GGIGGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNT----SPGPVS 115
G + AP+A P S + A +PP + + A P + T SPG S
Sbjct: 613 GEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLAS 672
Query: 116 SP-----GRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRS---ALSAGARRDTSG 166
SP G+ T L Q L++ +E + + E P S ++ A
Sbjct: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
Query: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH------STTEP 220
P P TP A A P PAP P +GP S S + H S P
Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
Query: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSP---------------------------- 252
SP R PS RP SR S S P P
Sbjct: 793 SPHPTRPPS------RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP 846
Query: 253 -ARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRKDAAPALGPLSSSPLATPSPS 310
+ P+A G P+ P P P+G L P P + P +A A +SS L P+PS
Sbjct: 847 ASNPAPTAPGPPQPPLRPQSQPPEG--PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
Query: 311 ----------GTKARPVPPPDNAATPLPATLPPSPP-----LATPLPL------------ 343
G P PPP P PA PP PP + TP P
Sbjct: 905 DFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFH 964
Query: 344 --------------APPSPSAPPSLQTLPSPPAT------PPSQAPPSMTTPPMQAPPSL 383
AP +P SL L SP A+ PS P + + P AP +
Sbjct: 965 QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAA 1024
Query: 384 QTIPPI----QVPHSLTSPSLQ----APPSPLALSSLQATTSLGS----PTLQATHSFLT 431
+PP+ + P+L A P S LQ + L PTLQ +
Sbjct: 1025 TGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACF 1084
Query: 432 MSP-RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
+ + Q S+ P + P L L P SP +
Sbjct: 1085 LEHLHKHQGSVLHPDYKTAFPSFEDALHRLL------PYHVYQGALPSPSDYHKVDEEFE 1138
Query: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPS---------LQTPPASLTTPPLENLPSL 541
+S+ QA L+ + LE ++P + +Q +L + L
Sbjct: 1139 TVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALD--KQLAKE 1196
Query: 542 APPPLQTASAPLTTP---HLETPPCPAPCPLQAP-PSPLTTPPPETPSSIATPPPQAPPA 597
P ++S L P E P PL + P T PPP P+ + + A
Sbjct: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVI---RHGGA 1253
Query: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
SP + + S L++ + +L + P P + P P+ T ++ L
Sbjct: 1254 GGSPSVTWARAS--SSLSSSSSSSSAASSLDADEDGPMPSRNRP--PIKTYEARSRIGLK 1309
Query: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
+ + Q S+ + A P+ PP PPA+ ++
Sbjct: 1310 LKIKQE--------------------------AGLSKVVHNTALDPVHQPPPPPATLKVA 1343
Query: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP--PRVPPLLAAPPLQVPPSPPAS 775
PP PPP V PPA+P P T P PR+P P P
Sbjct: 1344 EPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEG 1403
Query: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
P P PA L A+ + L L PPP+ P
Sbjct: 1404 TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDE--------LYQRMLKGPPPE-PAAS 1454
Query: 836 AA-----PLLQVPPSPPA------SPTL-QAPRRPPTPGPDT------SVSGPRLTLALA 877
AA P + P PPA SP + QA +P DT S L L A
Sbjct: 1455 AAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQA 1514
Query: 878 PGPPPPPSRSPSSTLSGP 895
PG P PS +++ P
Sbjct: 1515 PGRTPAPSYPHAASAGTP 1532
Score = 114 bits (284), Expect = 7e-25
Identities = 276/1084 (25%), Positives = 367/1084 (33%), Gaps = 171/1084 (15%)
Query: 15 RTPAARAPGLLTPRPPGSPRPPPPV----------------TPAALRVL--GAAGAVGRK 56
+ P A G P+PPG+ P V P + L GA +
Sbjct: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
Query: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRN-----PASRPPASGRGERAPPAKNTSP 111
L+ +GG + +AP G A N P S P A A S
Sbjct: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSA 544
Query: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171
P+ G+ + P L L ++ A AT + L A + P G
Sbjct: 545 API-QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTP-DGL 602
Query: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
PA + V +PAP A P T P ++ P+P A P A
Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT 662
Query: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-----PAHPSQP--KPKGLQALRPPQ 284
P S S L P + P+A T + P SQ +G P
Sbjct: 663 TPQPSPGLAS-SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721
Query: 285 V----TPPRKDAAPA--------LGPLSSSPLATPSPSGTKARPVP-----PPDNAATPL 327
V PP +D APA LGP + A+P+P+ P P + + P
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
A L SP L +P P P PS PPS P + PPS+ PP PP QAPP+L I
Sbjct: 782 QAPLGDSPHLPSPHPTRP--PSRPPS---RPQSVSRPPSE-PPLHPCPPPQAPPTLPGIF 835
Query: 388 PIQ----VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS 443
IQ VP ++P+ AP P Q+ G P A H + P T +++ S
Sbjct: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEG-PLPPAPH----LPPSSTSSAVAS 890
Query: 444 PSR-----PASTPPD----SPPLQAPLSLPASPP-LQTSLSPAVSPLSSPLTIH----PL 489
S PA TP D PP Q P P PP L PA P P T P
Sbjct: 891 SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
Query: 490 QAL---SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
AL +L Q P S +I L+ ++ AP + Q T+ L L S A L
Sbjct: 951 PALPQPKALLERFHQVP-SGII---LQNKAGGAPAAPQ------TSTSLGPLTSPAASVL 1000
Query: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP--PETPSSIATPPPQAPPALASPPLQ 604
+ AP TP T P AP P AP + PP P + A+ P A A+
Sbjct: 1001 VSGQAPSGTP---TAPSHAPAP--APMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
Query: 605 GLPS-----PPLSPLATPPPQAPPXLA--LPPLQAPPSPPASPPLSPLATPSPQAPNA-- 655
G PS LS L PP P A L L P T P +A
Sbjct: 1056 GKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYK---TAFPSFEDALH 1112
Query: 656 --LAVHLLQAPF-SPPPSPPVQAPFSPPA---------------------SPPVSPSATP 691
L H+ Q SP V F + S VSPSA
Sbjct: 1113 RLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEM 1172
Query: 692 PS------QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Q + A Q+ P S + P A ++ ++P P S
Sbjct: 1173 VMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIA---ASSEGHRLPGHGPLSS 1229
Query: 746 PMSPSAT-PPPRVPPLLAAPPLQVPPSPPA--SLPMSPLAKPPPQAPPALATPPLQALPS 802
++T PPP +P L SP + S L+ + A + + P
Sbjct: 1230 SAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPM 1289
Query: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTP 861
P + P + + + + V+ L PP P TL+ PP P
Sbjct: 1290 PSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRP 1349
Query: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG-PDLAGHSSSATST--PEELRGYDSGP 918
P +G ++ + PP P R P T P L + + P G +G
Sbjct: 1350 PPPPPPTG-QMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGR 1408
Query: 919 EGGAAASPPPD----------AELAACHPAAWSR---GPAPPLAFRGAPGAPLP-W---- 960
G + +P P ELAA + R GP P A A G P W
Sbjct: 1409 ARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPG 1468
Query: 961 -PPA 963
PPA
Sbjct: 1469 LPPA 1472
Score = 89.7 bits (221), Expect = 1e-17
Identities = 209/850 (24%), Positives = 281/850 (33%), Gaps = 145/850 (17%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
A TP A+ GL P P P P PAA + G G L +A +P
Sbjct: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP-GPSSSPSLPHQAPLGDSPHLP 792
Query: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP--AKNTSPG--------PVSSPGRAS 121
P P+R S SRPP+ PP A T PG V P
Sbjct: 793 SPHPTRPPSRPP--SRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
Query: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPK------RSALSAGARRDTSGPTPGTPSPA 175
T PGP Q LR ++ G AP SA+++ + + P P TPS
Sbjct: 851 APTAPGP-PQPPLRPQSQPP--EGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDF 906
Query: 176 MARRSRAAGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAA-----RR 226
+ + G P P P+ P P P ++ + P P A +
Sbjct: 907 QLQFPPSQGPHKS-PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQ 965
Query: 227 RPS-------AGGGLQRPASRSLSSSATPLSSPARS----GPSARGTPRAPAHPSQPKPK 275
PS AGG PA+ S+S PL+SPA S G + GTP AP+H P P
Sbjct: 966 VPSGIILQNKAGGA---PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPM 1022
Query: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP------------SGTKARPVPPPDNA 323
L PP + K A L L+ + A+ P SG K P P
Sbjct: 1023 AATGL-PPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKE 1081
Query: 324 ATPLP-------ATLPPSPPLATP---------LPL-----APPSPSAPPSLQTLPSPPA 362
A L + L P A P LP A PSPS + +
Sbjct: 1082 ACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVS 1141
Query: 363 TPPSQAPPSMTTP-PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS---------- 411
T + +M + + + P + +Q + LAL
Sbjct: 1142 TQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEY 1201
Query: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471
+ ++ SLG P ++ P S ++P PP P A
Sbjct: 1202 VSSSRSLGLPIAASSEGHRL--PGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSV 1259
Query: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531
+ + A S LSS + A SSL + P+ S PP++T + + L+
Sbjct: 1260 TWARASSSLSSSSSSS--SAASSLDADE-DGPMPSRNRPPIKTYEARSRIGLKLK----- 1311
Query: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT-- 589
++ L+ TA P+ P PP PA + PP PPP T T
Sbjct: 1312 ---IKQEAGLSKVVHNTALDPVHQP----PPPPATLKVAEPPPRPPPPPPPTGQMNGTVD 1364
Query: 590 -PPPQAPPALASPPLQGLPSPPLSPLAT----------PPPQAPPXLALPPLQAPPSPPA 638
PPP AP PL P P PL P P A AP
Sbjct: 1365 HPPPAAP---ERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKV 1421
Query: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPS--------PPVQAPFSPPA------SPP 684
S L + L +L+ P P + P +AP PPA SP
Sbjct: 1422 DEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPD 1481
Query: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
V ++ LQ + +P TP P P +A P SPP
Sbjct: 1482 VDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASA---GTPASPP-- 1536
Query: 745 PPMSPSATPP 754
P P A PP
Sbjct: 1537 PLHRPEAYPP 1546
Score = 55.5 bits (132), Expect = 3e-07
Identities = 65/237 (27%), Positives = 82/237 (34%), Gaps = 53/237 (22%)
Query: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821
A P+ PP PPA+L + A+PPP+ PP P P G P A+
Sbjct: 1326 ALDPVHQPPPPPATLKV---AEPPPRPPPP---------PPPTGQMNGTVDHPPPAAPER 1373
Query: 822 SPLATPPPQAPPVLAAPLLQV-------PPSPPASPTLQAPRRPPTPGP---DTSVSGPR 871
PL T AP PL + P +P +P +A P P P D + SG
Sbjct: 1374 KPLGT----APHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI 1429
Query: 872 LTLA---------LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 922
LA + GPPP P+ S + PD A P R P+
Sbjct: 1430 RELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW-----EAPGLPPAKRRKSESPDVDQ 1484
Query: 923 AA----SPPPDAELAACHPA---------AWSRGPAPPLAFRGAPGAPLPWPPATGP 966
A+ SP D A A R PAP + G P PP P
Sbjct: 1485 ASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP 1541
Score = 51.2 bits (121), Expect = 5e-06
Identities = 85/351 (24%), Positives = 114/351 (32%), Gaps = 44/351 (12%)
Query: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
A + P LS+ A ++ P P P+ + R A G+ AR
Sbjct: 1214 ASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSP-----SVTWARASSSL 1268
Query: 203 EGPRKSVSSASEHSTTEPSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
S S+AS E P +R RP ++ +RS + A
Sbjct: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPP----IKTYEARSRIGLKLKIKQEAGLSKVVHN 1324
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKD--------------AAPALGPLSSSPLATP 307
T P H P P L+ PP PP AAP PL ++P
Sbjct: 1325 TALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPR 1384
Query: 308 SP---------SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT-L 357
P G A P A PA LP AT + + Q L
Sbjct: 1385 LPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML 1444
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
PP P + A P +AP +PP + S + QA S + T
Sbjct: 1445 KGPPPEPAASAAQGTGDPDWEAPG----LPPAKRRKSESPDVDQASFSSDSPQDDTLTEH 1500
Query: 418 LGSPTLQATHSFLTM--SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
L S A S L + +P +T A + A TP PPL P + P S
Sbjct: 1501 LQS----AIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPS 1547
Score = 34.3 bits (77), Expect = 0.68
Identities = 61/251 (24%), Positives = 84/251 (33%), Gaps = 35/251 (13%)
Query: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
P P +AP P PP PT R G SV+ R + +L+ S S
Sbjct: 1222 PGHGPLSSSAPGASTQP-PPHLPTKLVIRHGGAGG-SPSVTWARASSSLSS------SSS 1273
Query: 888 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA-ACHPAAWS---RG 943
SS S D + ++ Y++ G +A L+ H A +
Sbjct: 1274 SSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQP 1333
Query: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE---------------SATPAP 988
P PP + A P P PP G +G PE T
Sbjct: 1334 PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRE 1393
Query: 989 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ--ASVVQHLLSRTLLLA 1046
PG GT G+A G S +P A++ E G ++ A+V L R L
Sbjct: 1394 NVGGPGAPEGTPAGRARGG------SPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
Query: 1047 AAEGAAGGSGG 1057
E AA + G
Sbjct: 1448 PPEPAASAAQG 1458
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 169 bits (428), Expect = 1e-41
Identities = 187/786 (23%), Positives = 275/786 (34%), Gaps = 83/786 (10%)
Query: 144 RGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPP 201
R K PK + AG+ D TP + + ++ + + ++ +P PP
Sbjct: 73 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 132
Query: 202 TEGPRKSVSSASEHSTT---EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
K S TT + + ++ S G + ++SA S ++ S
Sbjct: 133 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDG-------KEKTTSAKETQSIEKT--S 183
Query: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
A+ ++P PK + P +T P++ +S+ P+P+ K+ P
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378
P + P T AP +P P T P TP AP TT
Sbjct: 244 PKE--------------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP---TTTKEP 286
Query: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
AP + ++ P + T+P AP +P A T+ PT +P +
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTTP----KEPAPTTPKEPTPTTPKE---PAPTTKE 339
Query: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
+ T+P PA T P P AP + P P T PA + P P + +
Sbjct: 340 PAPTTPKEPAPTAPKKP---AP-TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Query: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT--TP 556
+P + P T + AP + + P + T P P P AP T P
Sbjct: 396 AP-----TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Query: 557 HLETPPCPAPCPLQAP-PSPLTTPPPETPSSIA-TPPPQAPPALASPPLQGLPSPPLSPL 614
TP PAP + P P+ P P TP A T P + P + P + P+ P P
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP---TTPEKLAPTTPEKPA 507
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
T P + P P P PA TP APN P P P+ P +
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAP------TTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 675 -APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA---PPPL 730
AP +P + P +P T P+ P P PA ++P+ T P + P
Sbjct: 562 PAPTTPKETAPTTPKGT-----APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616
Query: 731 AAPPLQVPPSPPASP----PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
P P+ P P P P+ T P P P P PA ++P P
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676
Query: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
+ + P + P + AP +P P +P TPPP V + P +
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTI 735
Query: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSS 903
SP P P P + P+ PG P P + P T + D
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPK-----EPGVPTTKTPAATKPEMTTTAKDKTTERDL 790
Query: 904 ATSTPE 909
T TPE
Sbjct: 791 RT-TPE 795
Score = 160 bits (404), Expect = 8e-39
Identities = 218/882 (24%), Positives = 311/882 (35%), Gaps = 137/882 (15%)
Query: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
T T+ N S P + AK +P P P S T++ + L ++ E
Sbjct: 101 TPDTSTTQHNKVSTSP------KITTAKPINPRPSLPPN--SDTSK-----ETSLTVNKE 147
Query: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
TV + T K+++ G + TS T S A T L +P P A
Sbjct: 148 TTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDLAPTSKVLAKPTPKAETT 204
Query: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
T+GP ++++ E + T P A P + P ++ S+ T PA +
Sbjct: 205 --TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTIKSAPTTPKEPAPTT--- 251
Query: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
T AP P +P P + P TP K+ AP + P+P+ TK+ P P
Sbjct: 252 --TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAP-------TTTKEPAPTTTKSAPTTP 298
Query: 320 PDNAAT----PLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPSQAP--PS 371
+ A T P P T P P TP P +P AP + + P+ P P AP P+
Sbjct: 299 KEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431
TTP AP T P P + PS P P ++ A T+ P T S T
Sbjct: 358 PTTPKEPAP----TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 432 M----SPRQT-QASLTSPSRPASTPPDSP----PLQAPLSLPASPPLQTSLSPAVSPLSS 482
SP T + + T+P PA T P P P + + P P T+ PA +
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 483 PLTIHPLQALSS------------LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
P P + + LA +P+ P + T LAP + + P +
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-------TPEELAPTTPEEPTPTT 526
Query: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPPPETPSSIAT 589
P P A P AP TTP P P P P + TTP P+++
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Query: 590 PPPQAPPALASPPLQGLPSPPLSPLAT----PPPQAPPXLA--LPPLQAPPSPPASPPLS 643
P P P A P + P+ P +T P P P A P AP +P P +
Sbjct: 586 PAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 643
Query: 644 PLAT------------PSPQAPNALAVHLLQAPFS-----PPPSPPVQAPFSPPASPPVS 686
P T P AP LA + P S P P+ P + + P +P
Sbjct: 644 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE---TAPTTPKEP 700
Query: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVPPSP-- 741
TP AP + PP P S +P+ T P P + P L P+P
Sbjct: 701 APTTPKKPAPTTPETPP------PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Query: 742 ----PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT--- 794
P P + + TP P + + + P + A P A T
Sbjct: 755 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 814
Query: 795 --PPLQALPSPPASFPGQ--APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
+ A + S Q PF +L + LA + + P A P
Sbjct: 815 TESKITATTTQVTSTTTQDTTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 873
Query: 851 TLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
+A + TP P P+ + P R P +T
Sbjct: 874 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 915
Score = 153 bits (387), Expect = 8e-37
Identities = 208/839 (24%), Positives = 288/839 (34%), Gaps = 147/839 (17%)
Query: 71 PESAPRAGPTRSAGTSSRNPA-SRPPASGRGERAPPAKNTSPGPVSSPGRASGTT--RPG 127
P S A PT A T+++ PA + P PA T P + +++ TT P
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 128 PLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P K + +E T + A PK A + T P P T A A
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-----TKEPAPTTTKSAPTTPKEPAP 303
Query: 185 TEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
T P P P P T + P + +T EP+P + P+
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP------------- 350
Query: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
++P + P+ TP+ PA P+ PK + P T P K+ AP + +
Sbjct: 351 ------TAPKKPAPT---TPKEPA-PTTPKEPAPTTTKEPSPTTP-KEPAPTTTKSAPTT 399
Query: 304 LATPSPSGTKARPVPP--PDNAATPLPA-TLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
P+P+ TK+ P P P T PA T P P TP AP +P P T P
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP--APTTPKE 457
Query: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
PA P + P+ TTP AP + + P T+P P +P L+ T +
Sbjct: 458 PA-PTTTKKPAPTTPKEPAPTTPKETAP-------TTPKKLTPTTPEKLA--PTTPEKPA 507
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
PT + + T+P P T P+ P AP + A+ P T PA +
Sbjct: 508 PT------------TPEELAPTTPEEPTPTTPEEP---APTTPKAAAP-NTPKEPAPTTP 551
Query: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
P +P P P ET AP TP + T E P+
Sbjct: 552 KEP---------------APTTPKEPAPTTPKET----AP---TTPKGTAPTTLKEPAPT 589
Query: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
P AP TT + C P P + TTP P++ P P P A
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
L+ P+P TP AP LA + P S + P TP AP
Sbjct: 650 TTLKE-PAP-----TTPKKPAPKELAPTTTKGPTSTTSDKPAP--TTPKETAPT------ 695
Query: 661 LQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPS--------QAPPSLAAPPLQVPPSPP 711
P P P+ P + AP +P PP + + P+ P + P L P+P
Sbjct: 696 --TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 753
Query: 712 A---SP--PMSPSATPPPQAPPPLAAPPLQ---------VPPSPPASPPMS--PSATPPP 755
A SP P P+ P P + P + A+P M+ + T
Sbjct: 754 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813
Query: 756 RVPPLLAAPPLQV--------PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807
+ A QV P +L + LA + T + P A
Sbjct: 814 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA-- 871
Query: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
P S TP PQ P A P P ++ P+ PTP TS
Sbjct: 872 ------KPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 923
Score = 147 bits (371), Expect = 6e-35
Identities = 174/692 (25%), Positives = 247/692 (35%), Gaps = 76/692 (10%)
Query: 369 PPSMTTP--PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
P + TT + P + T PI SL S + + L ++ + TT T
Sbjct: 102 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVN--KETTVETKETTTTN 159
Query: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
T +T ++ + S ++ D P L+ P T+ PA++ P
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219
Query: 487 HPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPPSLQTPPASLTTPPLENLP---- 539
P + S+ + S P E T + AP + + P + T P P
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279
Query: 540 ---SLAPPPLQTASAPLTT--PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
+ P P T SAP T P TP PAP + P TTP TP++ P P
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPTPTTPKEPAPTT 337
Query: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA-SPPLSPLATPSPQAP 653
+ P + P+ P P T P + P P P+ + P P T + AP
Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397
Query: 654 NALAVHLLQAPFSPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
S P +P +P + P + P P+ T P + P+ P P
Sbjct: 398 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 457
Query: 711 PASPPMSPSATPPPQAPPPL----AAP--PLQVPPSPP----ASPPMSPSATPPPRVPPL 760
PA A P+ P P AP P ++ P+ P + P P+ T P + P
Sbjct: 458 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517
Query: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820
P P PA P +P A P T P + P+ P AP +P + P
Sbjct: 518 TPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE---PAPTTPKETAP 572
Query: 821 MSPLATPPPQAPPVLAAPLLQVPPSP------------PASPTLQAPRRPPTPGPDTSVS 868
+P T AP L P P P P S T P PT T+ +
Sbjct: 573 TTPKGT----APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP--APTTPKGTAPT 626
Query: 869 GPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAAS 925
P+ P P P P + +TL P ++ P+EL + GP +
Sbjct: 627 TPKEPAPTTPKEPAPTTPKGTAPTTLKEP---APTTPKKPAPKELAPTTTKGPTSTTSDK 683
Query: 926 PPPDA--ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG----PGSADGLCTIYET- 978
P P E A P + PAP + AP P PP T P + TI+++
Sbjct: 684 PAPTTPKETAPTTP----KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739
Query: 979 --EGPE-SATPAPGALDPGP-SPGTSGGKAAA 1006
PE SA P P AL+ P PG K A
Sbjct: 740 DESTPELSAEPTPKALENSPKEPGVPTTKTPA 771
Score = 146 bits (369), Expect = 9e-35
Identities = 218/926 (23%), Positives = 308/926 (33%), Gaps = 119/926 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 200 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 247
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 248 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 296
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 297 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 341
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 401
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 458
Query: 302 SPLATPSPSGTKAR---PVPPPDNAATP-----------LPATLPPSPPLATPLPLAPPS 347
+P T P+ T + P P + A T L T P P TP LAP +
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518
Query: 348 PSAPPSLQTLPSPPATPPSQAP-----PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
P P P TP + AP P+ TTP AP T P P T+P A
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP----TTPKEPAP---TTPKETA 571
Query: 403 PPSP--LALSSLQ--ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
P +P A ++L+ A T+ P + T P T +P+ P T P +P
Sbjct: 572 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 631
Query: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSS 517
AP + P P T A + L P P + A LA + + P S+ P T
Sbjct: 632 APTT-PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690
Query: 518 LAPPSLQTPPASLTTP--PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575
P+ PA TTP P P PP S P TT + P +
Sbjct: 691 ETAPTTPKEPAP-TTPKKPAPTTPETPPPTTSEVSTPTTT--------------KEPTTI 735
Query: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ---APPXLALPPLQA 632
+P TP A P P+A SP G+P+ +P AT P A L+
Sbjct: 736 HKSPDESTPELSAEPTPKALEN--SPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRT 792
Query: 633 PPSPPASPP--LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
P + P AT + + + S + + ++P T
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 691 PPSQAPPSLAAPPLQVPPSPPASPP----MSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746
+ ++ + P A P S + TP PQ P P
Sbjct: 853 TTKK---TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRV 909
Query: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806
P TP PR + + P P S A + + P P +
Sbjct: 910 RKPKTTPTPR--KMTSTMPELNPTSRIAEAMLQTTTR--PNQTPNSKLVEVNPKSEDAGG 965
Query: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
G+ P P TP P P + +P S P G T
Sbjct: 966 AEGETPHMLLRPHVFMPEVTPDMDYLP--RVPNQGIIINPMLSDETNICNGKPVDGLTTL 1023
Query: 867 VSGPRLTL------ALAPGPPPPPSR 886
+G + L+P PP P+R
Sbjct: 1024 RNGTLVAFRGHYFWMLSPFSPPSPAR 1049
Score = 119 bits (298), Expect = 2e-26
Identities = 133/532 (25%), Positives = 175/532 (32%), Gaps = 48/532 (9%)
Query: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP-----PCPAPCPLQAPPSPLT 577
+ T P T P+ PSL PP T+ T + ET T
Sbjct: 112 VSTSPKITTAKPINPRPSL-PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 170
Query: 578 TPPPETPSS--------------IATPPPQAPPALASP----PLQGLPSPPLSPLATPPP 619
T ET S +A P P+A P P + P+ P P +T P
Sbjct: 171 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 230
Query: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS----PPVQA 675
+ P P P + S TP AP P P P+ P
Sbjct: 231 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290
Query: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
S P +P TP AP + P P P + P P+ T AP P
Sbjct: 291 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 350
Query: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
P P + P P+ T P P P P PA P + + P PA T
Sbjct: 351 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA--PTTTKSAPTTTKEPAPTT- 407
Query: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ-- 853
++ P+ P P+ + P P T P + P P PA T +
Sbjct: 408 -TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466
Query: 854 APRRPPTPGPDTSVSGPRLTLALAPG--PPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
AP P P P T P+ T P P P + +T P A +TPEE
Sbjct: 467 APTTPKEPAPTT----PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE- 521
Query: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSAD 970
+ PE A +P A PA + + PAP AP P P T G+A
Sbjct: 522 -PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 580
Query: 971 GLCTIYETEGPESATPAPGALDPGPS---PGTSGGKAAAGAGAGASSRSPKQ 1019
T+ E PAP L P + T+ K A G + +PK+
Sbjct: 581 --TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 169 bits (428), Expect = 1e-41
Identities = 187/786 (23%), Positives = 275/786 (34%), Gaps = 83/786 (10%)
Query: 144 RGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPP 201
R K PK + AG+ D TP + + ++ + + ++ +P PP
Sbjct: 114 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 173
Query: 202 TEGPRKSVSSASEHSTT---EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
K S TT + + ++ S G + ++SA S ++ S
Sbjct: 174 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDG-------KEKTTSAKETQSIEKT--S 224
Query: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
A+ ++P PK + P +T P++ +S+ P+P+ K+ P
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378
P + P T AP +P P T P TP AP TT
Sbjct: 285 PKE--------------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP---TTTKEP 327
Query: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
AP + ++ P + T+P AP +P A T+ PT +P +
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTTP----KEPAPTTPKEPTPTTPKE---PAPTTKE 380
Query: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
+ T+P PA T P P AP + P P T PA + P P + +
Sbjct: 381 PAPTTPKEPAPTAPKKP---AP-TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436
Query: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT--TP 556
+P + P T + AP + + P + T P P P AP T P
Sbjct: 437 AP-----TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491
Query: 557 HLETPPCPAPCPLQAP-PSPLTTPPPETPSSIA-TPPPQAPPALASPPLQGLPSPPLSPL 614
TP PAP + P P+ P P TP A T P + P + P + P+ P P
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP---TTPEKLAPTTPEKPA 548
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
T P + P P P PA TP APN P P P+ P +
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAP------TTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 675 -APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA---PPPL 730
AP +P + P +P T P+ P P PA ++P+ T P + P
Sbjct: 603 PAPTTPKETAPTTPKGT-----APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657
Query: 731 AAPPLQVPPSPPASP----PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
P P+ P P P P+ T P P P P PA ++P P
Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717
Query: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
+ + P + P + AP +P P +P TPPP V + P +
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTI 776
Query: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSS 903
SP P P P + P+ PG P P + P T + D
Sbjct: 777 HKSPDESTPELSAEPTPKALENSPK-----EPGVPTTKTPAATKPEMTTTAKDKTTERDL 831
Query: 904 ATSTPE 909
T TPE
Sbjct: 832 RT-TPE 836
Score = 160 bits (404), Expect = 8e-39
Identities = 218/882 (24%), Positives = 311/882 (35%), Gaps = 137/882 (15%)
Query: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
T T+ N S P + AK +P P P S T++ + L ++ E
Sbjct: 142 TPDTSTTQHNKVSTSP------KITTAKPINPRPSLPPN--SDTSK-----ETSLTVNKE 188
Query: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
TV + T K+++ G + TS T S A T L +P P A
Sbjct: 189 TTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDLAPTSKVLAKPTPKAETT 245
Query: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
T+GP ++++ E + T P A P + P ++ S+ T PA +
Sbjct: 246 --TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTIKSAPTTPKEPAPTT--- 292
Query: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
T AP P +P P + P TP K+ AP + P+P+ TK+ P P
Sbjct: 293 --TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAP-------TTTKEPAPTTTKSAPTTP 339
Query: 320 PDNAAT----PLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPSQAP--PS 371
+ A T P P T P P TP P +P AP + + P+ P P AP P+
Sbjct: 340 KEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431
TTP AP T P P + PS P P ++ A T+ P T S T
Sbjct: 399 PTTPKEPAP----TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 432 M----SPRQT-QASLTSPSRPASTPPDSP----PLQAPLSLPASPPLQTSLSPAVSPLSS 482
SP T + + T+P PA T P P P + + P P T+ PA +
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 514
Query: 483 PLTIHPLQALSS------------LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
P P + + LA +P+ P + T LAP + + P +
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-------TPEELAPTTPEEPTPTT 567
Query: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPPPETPSSIAT 589
P P A P AP TTP P P P P + TTP P+++
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626
Query: 590 PPPQAPPALASPPLQGLPSPPLSPLAT----PPPQAPPXLA--LPPLQAPPSPPASPPLS 643
P P P A P + P+ P +T P P P A P AP +P P +
Sbjct: 627 PAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 684
Query: 644 PLAT------------PSPQAPNALAVHLLQAPFS-----PPPSPPVQAPFSPPASPPVS 686
P T P AP LA + P S P P+ P + + P +P
Sbjct: 685 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE---TAPTTPKEP 741
Query: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVPPSP-- 741
TP AP + PP P S +P+ T P P + P L P+P
Sbjct: 742 APTTPKKPAPTTPETPP------PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795
Query: 742 ----PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT--- 794
P P + + TP P + + + P + A P A T
Sbjct: 796 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 855
Query: 795 --PPLQALPSPPASFPGQ--APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
+ A + S Q PF +L + LA + + P A P
Sbjct: 856 TESKITATTTQVTSTTTQDTTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 914
Query: 851 TLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
+A + TP P P+ + P R P +T
Sbjct: 915 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 956
Score = 153 bits (387), Expect = 8e-37
Identities = 208/839 (24%), Positives = 288/839 (34%), Gaps = 147/839 (17%)
Query: 71 PESAPRAGPTRSAGTSSRNPA-SRPPASGRGERAPPAKNTSPGPVSSPGRASGTT--RPG 127
P S A PT A T+++ PA + P PA T P + +++ TT P
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 128 PLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P K + +E T + A PK A + T P P T A A
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-----TKEPAPTTTKSAPTTPKEPAP 344
Query: 185 TEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
T P P P P T + P + +T EP+P + P+
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP------------- 391
Query: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
++P + P+ TP+ PA P+ PK + P T P K+ AP + +
Sbjct: 392 ------TAPKKPAPT---TPKEPA-PTTPKEPAPTTTKEPSPTTP-KEPAPTTTKSAPTT 440
Query: 304 LATPSPSGTKARPVPP--PDNAATPLPA-TLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
P+P+ TK+ P P P T PA T P P TP AP +P P T P
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP--APTTPKE 498
Query: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
PA P + P+ TTP AP + + P T+P P +P L+ T +
Sbjct: 499 PA-PTTTKKPAPTTPKEPAPTTPKETAP-------TTPKKLTPTTPEKLA--PTTPEKPA 548
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
PT + + T+P P T P+ P AP + A+ P T PA +
Sbjct: 549 PT------------TPEELAPTTPEEPTPTTPEEP---APTTPKAAAP-NTPKEPAPTTP 592
Query: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
P +P P P ET AP TP + T E P+
Sbjct: 593 KEP---------------APTTPKEPAPTTPKET----AP---TTPKGTAPTTLKEPAPT 630
Query: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
P AP TT + C P P + TTP P++ P P P A
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
L+ P+P TP AP LA + P S + P TP AP
Sbjct: 691 TTLKE-PAP-----TTPKKPAPKELAPTTTKGPTSTTSDKPAP--TTPKETAPT------ 736
Query: 661 LQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPS--------QAPPSLAAPPLQVPPSPP 711
P P P+ P + AP +P PP + + P+ P + P L P+P
Sbjct: 737 --TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 794
Query: 712 A---SP--PMSPSATPPPQAPPPLAAPPLQ---------VPPSPPASPPMS--PSATPPP 755
A SP P P+ P P + P + A+P M+ + T
Sbjct: 795 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854
Query: 756 RVPPLLAAPPLQV--------PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807
+ A QV P +L + LA + T + P A
Sbjct: 855 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA-- 912
Query: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
P S TP PQ P A P P ++ P+ PTP TS
Sbjct: 913 ------KPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 964
Score = 147 bits (371), Expect = 6e-35
Identities = 174/692 (25%), Positives = 247/692 (35%), Gaps = 76/692 (10%)
Query: 369 PPSMTTP--PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
P + TT + P + T PI SL S + + L ++ + TT T
Sbjct: 143 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVN--KETTVETKETTTTN 200
Query: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
T +T ++ + S ++ D P L+ P T+ PA++ P
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260
Query: 487 HPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPPSLQTPPASLTTPPLENLP---- 539
P + S+ + S P E T + AP + + P + T P P
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320
Query: 540 ---SLAPPPLQTASAPLTT--PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
+ P P T SAP T P TP PAP + P TTP TP++ P P
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPTPTTPKEPAPTT 378
Query: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA-SPPLSPLATPSPQAP 653
+ P + P+ P P T P + P P P+ + P P T + AP
Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438
Query: 654 NALAVHLLQAPFSPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
S P +P +P + P + P P+ T P + P+ P P
Sbjct: 439 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 498
Query: 711 PASPPMSPSATPPPQAPPPL----AAP--PLQVPPSPP----ASPPMSPSATPPPRVPPL 760
PA A P+ P P AP P ++ P+ P + P P+ T P + P
Sbjct: 499 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558
Query: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820
P P PA P +P A P T P + P+ P AP +P + P
Sbjct: 559 TPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE---PAPTTPKETAP 613
Query: 821 MSPLATPPPQAPPVLAAPLLQVPPSP------------PASPTLQAPRRPPTPGPDTSVS 868
+P T AP L P P P P S T P PT T+ +
Sbjct: 614 TTPKGT----APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP--APTTPKGTAPT 667
Query: 869 GPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAAS 925
P+ P P P P + +TL P ++ P+EL + GP +
Sbjct: 668 TPKEPAPTTPKEPAPTTPKGTAPTTLKEP---APTTPKKPAPKELAPTTTKGPTSTTSDK 724
Query: 926 PPPDA--ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG----PGSADGLCTIYET- 978
P P E A P + PAP + AP P PP T P + TI+++
Sbjct: 725 PAPTTPKETAPTTP----KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780
Query: 979 --EGPE-SATPAPGALDPGP-SPGTSGGKAAA 1006
PE SA P P AL+ P PG K A
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPA 812
Score = 146 bits (369), Expect = 9e-35
Identities = 218/926 (23%), Positives = 308/926 (33%), Gaps = 119/926 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 241 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 288
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 289 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 337
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 338 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 382
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 442
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 499
Query: 302 SPLATPSPSGTKAR---PVPPPDNAATP-----------LPATLPPSPPLATPLPLAPPS 347
+P T P+ T + P P + A T L T P P TP LAP +
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 348 PSAPPSLQTLPSPPATPPSQAP-----PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
P P P TP + AP P+ TTP AP T P P T+P A
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP----TTPKEPAP---TTPKETA 612
Query: 403 PPSP--LALSSLQ--ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
P +P A ++L+ A T+ P + T P T +P+ P T P +P
Sbjct: 613 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 672
Query: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSS 517
AP + P P T A + L P P + A LA + + P S+ P T
Sbjct: 673 APTT-PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731
Query: 518 LAPPSLQTPPASLTTP--PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575
P+ PA TTP P P PP S P TT + P +
Sbjct: 732 ETAPTTPKEPAP-TTPKKPAPTTPETPPPTTSEVSTPTTT--------------KEPTTI 776
Query: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ---APPXLALPPLQA 632
+P TP A P P+A SP G+P+ +P AT P A L+
Sbjct: 777 HKSPDESTPELSAEPTPKALEN--SPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRT 833
Query: 633 PPSPPASPP--LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
P + P AT + + + S + + ++P T
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 691 PPSQAPPSLAAPPLQVPPSPPASPP----MSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746
+ ++ + P A P S + TP PQ P P
Sbjct: 894 TTKK---TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRV 950
Query: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806
P TP PR + + P P S A + + P P +
Sbjct: 951 RKPKTTPTPR--KMTSTMPELNPTSRIAEAMLQTTTR--PNQTPNSKLVEVNPKSEDAGG 1006
Query: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
G+ P P TP P P + +P S P G T
Sbjct: 1007 AEGETPHMLLRPHVFMPEVTPDMDYLP--RVPNQGIIINPMLSDETNICNGKPVDGLTTL 1064
Query: 867 VSGPRLTL------ALAPGPPPPPSR 886
+G + L+P PP P+R
Sbjct: 1065 RNGTLVAFRGHYFWMLSPFSPPSPAR 1090
Score = 119 bits (298), Expect = 2e-26
Identities = 133/532 (25%), Positives = 175/532 (32%), Gaps = 48/532 (9%)
Query: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP-----PCPAPCPLQAPPSPLT 577
+ T P T P+ PSL PP T+ T + ET T
Sbjct: 153 VSTSPKITTAKPINPRPSL-PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 211
Query: 578 TPPPETPSS--------------IATPPPQAPPALASP----PLQGLPSPPLSPLATPPP 619
T ET S +A P P+A P P + P+ P P +T P
Sbjct: 212 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 271
Query: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS----PPVQA 675
+ P P P + S TP AP P P P+ P
Sbjct: 272 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331
Query: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
S P +P TP AP + P P P + P P+ T AP P
Sbjct: 332 TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 391
Query: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
P P + P P+ T P P P P PA P + + P PA T
Sbjct: 392 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA--PTTTKSAPTTTKEPAPTT- 448
Query: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ-- 853
++ P+ P P+ + P P T P + P P PA T +
Sbjct: 449 -TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507
Query: 854 APRRPPTPGPDTSVSGPRLTLALAPG--PPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
AP P P P T P+ T P P P + +T P A +TPEE
Sbjct: 508 APTTPKEPAPTT----PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE- 562
Query: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSAD 970
+ PE A +P A PA + + PAP AP P P T G+A
Sbjct: 563 -PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 621
Query: 971 GLCTIYETEGPESATPAPGALDPGPS---PGTSGGKAAAGAGAGASSRSPKQ 1019
T+ E PAP L P + T+ K A G + +PK+
Sbjct: 622 --TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 169 bits (428), Expect = 1e-41
Identities = 194/837 (23%), Positives = 286/837 (34%), Gaps = 128/837 (15%)
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---------QR 236
EV P PS++ PP G +++ S ++ S P+ ++ + Q
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
+S S SSS++ +S ++ K + + P PP D A +
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184
Query: 297 GPLSSSPLATP------------SPSGTKARPVPP----PDNAATPLPATL--------- 331
+ TP SP T A+P+ P P N+ T +L
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244
Query: 332 -------------------------------------PPSPPLATPLPLAPPSPSAPPSL 354
P S LA P P A + P
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP--A 302
Query: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--PIQVPHSLTSPSLQAPPSPLALSSL 412
T P P TP + P+ TTP P ++++ P P + + T + P P ++
Sbjct: 303 LTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 413 QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472
+ + +P A + +P T+++ T+P PA T P P P + P +
Sbjct: 362 EPAPT--TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP- 418
Query: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
+P +P T P A +P+ P + P T P+ PA TT
Sbjct: 419 -TPTTPKEPAPTTKEP-------APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470
Query: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592
P P T SAP TT PAP ++ P TTP +P++ P P
Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKE------PAPTTTKSAP---TTPKEPSPTTTKEPAP 521
Query: 593 QAPPALA-SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA--SPPLSPLATPS 649
P A + P + P+ P P T P + P P P PA +P + TP
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581
Query: 650 PQAPNALAVHLLQAPFSPPPSPPVQ----APFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
P P P P+ P + P P + P P+ T P A P+ P
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 641
Query: 706 VPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
P PA + P P+ T P + P P P + P +P P + P
Sbjct: 642 TTPKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 699
Query: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
P PA P +P P T P + P+ P G AP + P +P
Sbjct: 700 PTSTTCDKPA--PTTPKGTAPTTPKEPAPTTPKEPAPTTP---KGTAPTTLKEPAPTTPK 754
Query: 825 ATPPPQ-APPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
P + AP P P P +P AP P P P T P+ P PP
Sbjct: 755 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT----PKKPAPTTPETPP 810
Query: 883 P---------PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930
P ++ P++ PD + SA TP+ L +S E G + P A
Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE--NSPKEPGVPTTKTPAA 865
Score = 161 bits (407), Expect = 4e-39
Identities = 220/883 (24%), Positives = 305/883 (34%), Gaps = 156/883 (17%)
Query: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
T T+ N S P + AK +P P P S T++ + L ++ E
Sbjct: 194 TPDTSTTQHNKVSTSP------KITTAKPINPRPSLPPN--SDTSK-----ETSLTVNKE 240
Query: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
TV + T K+++ G + TS T S A T L +P P A
Sbjct: 241 TTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDLAPTSKVLAKPTPKAETT 297
Query: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
T+GP ++++ E + T P A P + P ++ S+ T PA +
Sbjct: 298 --TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTIKSAPTTPKEPAPTT--- 344
Query: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
T AP P +P P + P TP K+ AP + P+P+ TK+ P P
Sbjct: 345 --TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAP-------TTTKEPAPTTTKSAPTTP 391
Query: 320 PDNAAT----PLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPSQAP--PS 371
+ A T P P T P P TP P +P AP + + P+ P P AP P+
Sbjct: 392 KEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP--PSPLALSSLQATTSLGSPTLQATHSF 429
TTP AP T P P + PS P P+P S TT +PT +
Sbjct: 451 PTTPKEPAP----TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
P T +P+ P P +P AP + P P T PA + P P
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAP-----PSLQTPPASLTTPPLENLPSLAPP 544
+ + + AP + + P T LAP P+ TP T P E P+
Sbjct: 566 EPAPTTPKET--APTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 545 PLQT---ASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIA-TPPPQAPPALA 599
P T A+AP TP PAP P + P+ P P TP A T P P
Sbjct: 623 PAPTTPKAAAP------NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676
Query: 600 SPPLQGLPSPP----LSPLATPPPQAP----PXLALPPLQAPPSPPASPPLSPLATPSPQ 651
P P P L+P T P + P P AP +P P +P P+P
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP-KEPAPT 735
Query: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAP--PLQVPP 708
P A L+ P P P +P + P S ++ P+ P AP P + P
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 709 SPPASPPMSPSATPPPQAP-----------------PPLAAPPLQVPPSP------PASP 745
+ P P + TPPP P + P L P+P P P
Sbjct: 796 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Query: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP-----LQAL 800
+ + TP P + + + P + A P A T + A
Sbjct: 856 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 915
Query: 801 PSPPASFPGQ--APFS----------------------------------PSASLPMSPL 824
+ S Q PF P S
Sbjct: 916 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 975
Query: 825 ATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTS 866
TP PQ P AP P + P ++ P+ PTP TS
Sbjct: 976 TTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1016
Score = 156 bits (395), Expect = 9e-38
Identities = 202/826 (24%), Positives = 285/826 (34%), Gaps = 100/826 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 293 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 340
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 341 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 389
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 390 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 434
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 494
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 551
Query: 302 SPLATPSPSGTKAR---PVPPPDNAAT-----------PLPATLPPSPPLATPLPLAPPS 347
+P T P+ T + P P + A T L T P P TP LAP +
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 611
Query: 348 PSAPPSLQTLPSPPATPPSQAP-----PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
P P P TP + AP P+ TTP AP T P P T+P A
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP----TTPKEPAP---TTPKETA 664
Query: 403 PPSP--LALSSLQ--ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
P +P A ++L+ A T+ P + T P T +P+ P T P +P
Sbjct: 665 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 724
Query: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSS 517
AP + P P T A + L P P + A LA + + P S+ P T
Sbjct: 725 AP-TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783
Query: 518 LAPPSLQTPPASLTTP--PLENLPSLAPPPLQTASAPLTT---------PHLETPPCPA- 565
P+ PA TTP P P PP S P TT P TP A
Sbjct: 784 ETAPTTPKEPAP-TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842
Query: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
P P SP P T + AT P A + L + P T P+
Sbjct: 843 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP--ETTTAAPKMTKET 900
Query: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
A + S + +T + L +P + + +
Sbjct: 901 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 960
Query: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
+A P +A S A P P P P P++T P+ P + P + P+P
Sbjct: 961 EETAKPKDRATNSKATTP---KPQKPTKAPKKPTSTKKPKTMPRVRKP--KTTPTPRKMT 1015
Query: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791
P P R+ A + + P P S L + P++ A
Sbjct: 1016 STMPELNPTSRI-----AEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1056
Score = 124 bits (310), Expect = 7e-28
Identities = 165/692 (23%), Positives = 236/692 (34%), Gaps = 55/692 (7%)
Query: 347 SPSAPPSLQTLPSPPATPPSQAPPSM--TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
+P++PPS S A PPS A ++ TT PP+ + + +T +
Sbjct: 68 NPTSPPS-----SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE---EHSV 119
Query: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSP-RQTQASLTSPSRPASTPPDSPPLQAPLSL 463
S SS +++S S T++ S + R+ Q L + P + P+
Sbjct: 120 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 179
Query: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
A L +P +S T H + S SP+ + P+ + SL P S
Sbjct: 180 EAGSGLDNGDFKVTTPDTST-TQH------NKVSTSPKITTAK----PINPRPSLPPNSD 228
Query: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
+ SLT + ++ T + +T E S P T
Sbjct: 229 TSKETSLT---VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP--T 283
Query: 584 PSSIATPPPQAPPALASP----PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
+A P P+A P P + P+ P P +T P + P P P +
Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343
Query: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPS----PPVQAPFSPPASPPVSPSATPPSQA 695
S TP AP P P P+ P S P +P TP A
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755
P + P P P + P P+ T AP P P P + P P+ T P
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
P P P PA P + + P PA T ++ P+ P P
Sbjct: 464 EPAPTTTKEPSPTTPKEPA--PTTTKSAPTTTKEPAPTT--TKSAPTTPKEPSPTTTKEP 519
Query: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ--APRRPPTPGPDTSVSGPRLT 873
+ + P P T P + P P PA T + AP P P P T P+ T
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT----PKET 575
Query: 874 LALAPG--PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 931
P P P + +T P A +TPEE + PE A +P A
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAP 633
Query: 932 LAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990
PA + + PAP AP P P T G+A T+ E PAP
Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP--TTLKEPAPTTPKKPAPKE 691
Query: 991 LDPGPS---PGTSGGKAAAGAGAGASSRSPKQ 1019
L P + T+ K A G + +PK+
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723
Score = 60.1 bits (144), Expect = 1e-08
Identities = 117/525 (22%), Positives = 169/525 (32%), Gaps = 120/525 (22%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
PA P P P P P P PA A ++ G T+ E AP
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPA--KNTSPGPVSSPGRASGTT--RPGPLGQK 132
P + A ++ P S ++ P K T+P ++P + TT P P K
Sbjct: 683 T-PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKEPAPTTPKEPAPTTPK 738
Query: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPR 191
G T + A PK+ A A T GPT T PA A T P
Sbjct: 739 G----TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 794
Query: 192 PAPSARPRPPT-EGPRKSVSSASEHSTT-------------------EPSPAARRRPSAG 231
P +P P T E P + S S +TT EP+P A
Sbjct: 795 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 854
Query: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP----AHPSQPK-------------- 273
G+ P +++ +++ +++ A+ + R P A P K
Sbjct: 855 PGV--PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKI 912
Query: 274 ----------------PKGLQALRP----PQVTPPRK------------DAAPALGPLSS 301
P + L+ P+VT +K + A ++
Sbjct: 913 TATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATN 972
Query: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPP-SPPLATPLP---------LAPPSPSAP 351
S TP P P P +T P T+P P TP P L P S A
Sbjct: 973 SKATTPKPQKPTKAPKKP---TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1029
Query: 352 PSLQTLPSPPATPPS-----------------QAPPSMTTPPMQAP---PSLQTIPPIQV 391
LQT P TP S + P + P + P P + +P +
Sbjct: 1030 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPN 1089
Query: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA--THSFLTMSP 434
+ +P L + + T+L + TL A H F +SP
Sbjct: 1090 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLSP 1134
Score = 48.1 bits (113), Expect = 5e-05
Identities = 84/374 (22%), Positives = 124/374 (33%), Gaps = 43/374 (11%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
A TP AP L P +P+ P P A G KP T E
Sbjct: 733 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792
Query: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV-SSPGRASGTTRPGPLGQ 131
AP P + A T+ P PP + E + P P + SP ++ P
Sbjct: 793 PAPTT-PKKPAPTTPETP---PPTTS--EVSTPTTTKEPTTIHKSPDESTPELSAEPT-P 845
Query: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSG----PTPGTPSPAMARRSRAAGTEV 187
K L S +E T A + ++ A+ T+ TP T + A A T
Sbjct: 846 KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 905
Query: 188 GLPRPAPSARPRPPTEGPR-----------KSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
+A T K+ + A + +TT+ + + +
Sbjct: 906 KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 965
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPA 295
P R+ +S AT P + +AP P S KPK + +R P+ TP +
Sbjct: 966 PKDRATNSKATT--------PKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTST 1017
Query: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-----TPLPLAPP---S 347
+ L+ + + T RP P+ + L P S TP L P
Sbjct: 1018 MPELNPTSRIAEAMLQTTTRPNQTPN---SKLVEVNPKSEDAGGAEGETPHMLLRPHVFM 1074
Query: 348 PSAPPSLQTLPSPP 361
P P + LP P
Sbjct: 1075 PEVTPDMDYLPRVP 1088
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 169 bits (428), Expect = 1e-41
Identities = 194/837 (23%), Positives = 286/837 (34%), Gaps = 128/837 (15%)
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---------QR 236
EV P PS++ PP G +++ S ++ S P+ ++ + Q
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
+S S SSS++ +S ++ K + + P PP D A +
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225
Query: 297 GPLSSSPLATP------------SPSGTKARPVPP----PDNAATPLPATL--------- 331
+ TP SP T A+P+ P P N+ T +L
Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285
Query: 332 -------------------------------------PPSPPLATPLPLAPPSPSAPPSL 354
P S LA P P A + P
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP--A 343
Query: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--PIQVPHSLTSPSLQAPPSPLALSSL 412
T P P TP + P+ TTP P ++++ P P + + T + P P ++
Sbjct: 344 LTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 413 QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472
+ + +P A + +P T+++ T+P PA T P P P + P +
Sbjct: 403 EPAPT--TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP- 459
Query: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
+P +P T P A +P+ P + P T P+ PA TT
Sbjct: 460 -TPTTPKEPAPTTKEP-------APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511
Query: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592
P P T SAP TT PAP ++ P TTP +P++ P P
Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKE------PAPTTTKSAP---TTPKEPSPTTTKEPAP 562
Query: 593 QAPPALA-SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA--SPPLSPLATPS 649
P A + P + P+ P P T P + P P P PA +P + TP
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622
Query: 650 PQAPNALAVHLLQAPFSPPPSPPVQ----APFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
P P P P+ P + P P + P P+ T P A P+ P
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 682
Query: 706 VPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
P PA + P P+ T P + P P P + P +P P + P
Sbjct: 683 TTPKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 740
Query: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
P PA P +P P T P + P+ P G AP + P +P
Sbjct: 741 PTSTTCDKPA--PTTPKGTAPTTPKEPAPTTPKEPAPTTP---KGTAPTTLKEPAPTTPK 795
Query: 825 ATPPPQ-APPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
P + AP P P P +P AP P P P T P+ P PP
Sbjct: 796 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT----PKKPAPTTPETPP 851
Query: 883 P---------PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930
P ++ P++ PD + SA TP+ L +S E G + P A
Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE--NSPKEPGVPTTKTPAA 906
Score = 161 bits (407), Expect = 4e-39
Identities = 220/883 (24%), Positives = 305/883 (34%), Gaps = 156/883 (17%)
Query: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
T T+ N S P + AK +P P P S T++ + L ++ E
Sbjct: 235 TPDTSTTQHNKVSTSP------KITTAKPINPRPSLPPN--SDTSK-----ETSLTVNKE 281
Query: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
TV + T K+++ G + TS T S A T L +P P A
Sbjct: 282 TTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDLAPTSKVLAKPTPKAETT 338
Query: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
T+GP ++++ E + T P A P + P ++ S+ T PA +
Sbjct: 339 --TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTIKSAPTTPKEPAPTT--- 385
Query: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
T AP P +P P + P TP K+ AP + P+P+ TK+ P P
Sbjct: 386 --TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAP-------TTTKEPAPTTTKSAPTTP 432
Query: 320 PDNAAT----PLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPSQAP--PS 371
+ A T P P T P P TP P +P AP + + P+ P P AP P+
Sbjct: 433 KEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP--PSPLALSSLQATTSLGSPTLQATHSF 429
TTP AP T P P + PS P P+P S TT +PT +
Sbjct: 492 PTTPKEPAP----TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
P T +P+ P P +P AP + P P T PA + P P
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAP-----PSLQTPPASLTTPPLENLPSLAPP 544
+ + + AP + + P T LAP P+ TP T P E P+
Sbjct: 607 EPAPTTPKET--APTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 545 PLQT---ASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIA-TPPPQAPPALA 599
P T A+AP TP PAP P + P+ P P TP A T P P
Sbjct: 664 PAPTTPKAAAP------NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 717
Query: 600 SPPLQGLPSPP----LSPLATPPPQAP----PXLALPPLQAPPSPPASPPLSPLATPSPQ 651
P P P L+P T P + P P AP +P P +P P+P
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP-KEPAPT 776
Query: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAP--PLQVPP 708
P A L+ P P P +P + P S ++ P+ P AP P + P
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 709 SPPASPPMSPSATPPPQAP-----------------PPLAAPPLQVPPSP------PASP 745
+ P P + TPPP P + P L P+P P P
Sbjct: 837 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Query: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP-----LQAL 800
+ + TP P + + + P + A P A T + A
Sbjct: 897 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 956
Query: 801 PSPPASFPGQ--APFS----------------------------------PSASLPMSPL 824
+ S Q PF P S
Sbjct: 957 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 1016
Query: 825 ATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTS 866
TP PQ P AP P + P ++ P+ PTP TS
Sbjct: 1017 TTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1057
Score = 156 bits (395), Expect = 9e-38
Identities = 202/826 (24%), Positives = 285/826 (34%), Gaps = 100/826 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 334 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 381
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 382 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 430
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 431 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 475
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 535
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 592
Query: 302 SPLATPSPSGTKAR---PVPPPDNAAT-----------PLPATLPPSPPLATPLPLAPPS 347
+P T P+ T + P P + A T L T P P TP LAP +
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 652
Query: 348 PSAPPSLQTLPSPPATPPSQAP-----PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
P P P TP + AP P+ TTP AP T P P T+P A
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP----TTPKEPAP---TTPKETA 705
Query: 403 PPSP--LALSSLQ--ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
P +P A ++L+ A T+ P + T P T +P+ P T P +P
Sbjct: 706 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 765
Query: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSS 517
AP + P P T A + L P P + A LA + + P S+ P T
Sbjct: 766 AP-TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824
Query: 518 LAPPSLQTPPASLTTP--PLENLPSLAPPPLQTASAPLTT---------PHLETPPCPA- 565
P+ PA TTP P P PP S P TT P TP A
Sbjct: 825 ETAPTTPKEPAP-TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883
Query: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
P P SP P T + AT P A + L + P T P+
Sbjct: 884 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP--ETTTAAPKMTKET 941
Query: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
A + S + +T + L +P + + +
Sbjct: 942 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 1001
Query: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
+A P +A S A P P P P P++T P+ P + P + P+P
Sbjct: 1002 EETAKPKDRATNSKATTP---KPQKPTKAPKKPTSTKKPKTMPRVRKP--KTTPTPRKMT 1056
Query: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791
P P R+ A + + P P S L + P++ A
Sbjct: 1057 STMPELNPTSRI-----AEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1097
Score = 124 bits (310), Expect = 7e-28
Identities = 165/692 (23%), Positives = 236/692 (34%), Gaps = 55/692 (7%)
Query: 347 SPSAPPSLQTLPSPPATPPSQAPPSM--TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
+P++PPS S A PPS A ++ TT PP+ + + +T +
Sbjct: 109 NPTSPPS-----SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE---EHSV 160
Query: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSP-RQTQASLTSPSRPASTPPDSPPLQAPLSL 463
S SS +++S S T++ S + R+ Q L + P + P+
Sbjct: 161 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 220
Query: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
A L +P +S T H + S SP+ + P+ + SL P S
Sbjct: 221 EAGSGLDNGDFKVTTPDTST-TQH------NKVSTSPKITTAK----PINPRPSLPPNSD 269
Query: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
+ SLT + ++ T + +T E S P T
Sbjct: 270 TSKETSLT---VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP--T 324
Query: 584 PSSIATPPPQAPPALASP----PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
+A P P+A P P + P+ P P +T P + P P P +
Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384
Query: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPS----PPVQAPFSPPASPPVSPSATPPSQA 695
S TP AP P P P+ P S P +P TP A
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755
P + P P P + P P+ T AP P P P + P P+ T P
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
P P P PA P + + P PA T ++ P+ P P
Sbjct: 505 EPAPTTTKEPSPTTPKEPA--PTTTKSAPTTTKEPAPTT--TKSAPTTPKEPSPTTTKEP 560
Query: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ--APRRPPTPGPDTSVSGPRLT 873
+ + P P T P + P P PA T + AP P P P T P+ T
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT----PKET 616
Query: 874 LALAPG--PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 931
P P P + +T P A +TPEE + PE A +P A
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAP 674
Query: 932 LAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990
PA + + PAP AP P P T G+A T+ E PAP
Sbjct: 675 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP--TTLKEPAPTTPKKPAPKE 732
Query: 991 LDPGPS---PGTSGGKAAAGAGAGASSRSPKQ 1019
L P + T+ K A G + +PK+
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764
Score = 60.1 bits (144), Expect = 1e-08
Identities = 117/525 (22%), Positives = 169/525 (32%), Gaps = 120/525 (22%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
PA P P P P P P PA A ++ G T+ E AP
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPA--KNTSPGPVSSPGRASGTT--RPGPLGQK 132
P + A ++ P S ++ P K T+P ++P + TT P P K
Sbjct: 724 T-PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKEPAPTTPKEPAPTTPK 779
Query: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPR 191
G T + A PK+ A A T GPT T PA A T P
Sbjct: 780 G----TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 835
Query: 192 PAPSARPRPPT-EGPRKSVSSASEHSTT-------------------EPSPAARRRPSAG 231
P +P P T E P + S S +TT EP+P A
Sbjct: 836 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 895
Query: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP----AHPSQPK-------------- 273
G+ P +++ +++ +++ A+ + R P A P K
Sbjct: 896 PGV--PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKI 953
Query: 274 ----------------PKGLQALRP----PQVTPPRK------------DAAPALGPLSS 301
P + L+ P+VT +K + A ++
Sbjct: 954 TATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATN 1013
Query: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPP-SPPLATPLP---------LAPPSPSAP 351
S TP P P P +T P T+P P TP P L P S A
Sbjct: 1014 SKATTPKPQKPTKAPKKP---TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1070
Query: 352 PSLQTLPSPPATPPS-----------------QAPPSMTTPPMQAP---PSLQTIPPIQV 391
LQT P TP S + P + P + P P + +P +
Sbjct: 1071 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPN 1130
Query: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA--THSFLTMSP 434
+ +P L + + T+L + TL A H F +SP
Sbjct: 1131 QGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLSP 1175
Score = 48.1 bits (113), Expect = 5e-05
Identities = 84/374 (22%), Positives = 124/374 (33%), Gaps = 43/374 (11%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
A TP AP L P +P+ P P A G KP T E
Sbjct: 774 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833
Query: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV-SSPGRASGTTRPGPLGQ 131
AP P + A T+ P PP + E + P P + SP ++ P
Sbjct: 834 PAPTT-PKKPAPTTPETP---PPTTS--EVSTPTTTKEPTTIHKSPDESTPELSAEPT-P 886
Query: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSG----PTPGTPSPAMARRSRAAGTEV 187
K L S +E T A + ++ A+ T+ TP T + A A T
Sbjct: 887 KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 946
Query: 188 GLPRPAPSARPRPPTEGPR-----------KSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
+A T K+ + A + +TT+ + + +
Sbjct: 947 KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 1006
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPA 295
P R+ +S AT P + +AP P S KPK + +R P+ TP +
Sbjct: 1007 PKDRATNSKATT--------PKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTST 1058
Query: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-----TPLPLAPP---S 347
+ L+ + + T RP P+ + L P S TP L P
Sbjct: 1059 MPELNPTSRIAEAMLQTTTRPNQTPN---SKLVEVNPKSEDAGGAEGETPHMLLRPHVFM 1115
Query: 348 PSAPPSLQTLPSPP 361
P P + LP P
Sbjct: 1116 PEVTPDMDYLPRVP 1129
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 169 bits (428), Expect = 1e-41
Identities = 201/774 (25%), Positives = 280/774 (36%), Gaps = 157/774 (20%)
Query: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
SS +SG S+ P + ++ S G+ +P + + + T
Sbjct: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFS--EAWKRGTQLE 588
Query: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
+KAR + + T L L P P + TP + PSP PP P PP PP P
Sbjct: 589 ESSKAR-MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLT---------SPSLQAPPSPLALSSLQATTSLGS 420
P P Q+ PS + P+ V +S S +L PP+P + S +
Sbjct: 648 PL----PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703
Query: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
P P T S + +PA P P AP PPL+ ++ +
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP-----PPPLKIHQVQHITQV 758
Query: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
+ P P + L PQAP L+ P T + P + TPP+ P+
Sbjct: 759 APPTPPPPPPIPAPL---PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP--PA 813
Query: 541 LAPPPLQTASAPLTTPHLETPPCPAPCP---------LQAPPSPLTTPPPETPSSIAT-- 589
P + P + P TPP P P P + PPSPL +P P IA+
Sbjct: 814 KKQPAFPASYIPPSPP---TPPVPVPPPTLPKQQSFCAKPPPSPL-SPVPSVVKQIASQF 869
Query: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
PPP PPA+ S PL+ +P A PQ+PP + P P S P P P
Sbjct: 870 PPPPTPPAMESQPLKPVP-------ANVAPQSPPAVKAKPKWQPSSIPVPSPDFP----- 917
Query: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPP---ASPPVSPSATPPSQAPPSLAAPPLQV 706
P P + V F PPP PV AP PP ASP S +P + + + +
Sbjct: 918 PPPPESSLV------FPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971
Query: 707 PPSPPASPPMSPSA---TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP---L 760
PP+P + + S+ P P+ P + PP+ SP S PPP PP
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP--SKETLPPPAAPPKPGK 1029
Query: 761 LAAPPLQVP--------------------------PSPPASLPMSPLAKPPPQAPPALAT 794
L + +P PSPP+ P PPP+ L
Sbjct: 1030 LNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP---PPPET--ELPL 1084
Query: 795 PPLQALPSPPASFPGQAPFSPSASL---------PMSPLATPPPQAP------------- 832
PP++ PA F G SP ++ MS PPP P
Sbjct: 1085 PPIEI----PAVFSGNT--SPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEI 1138
Query: 833 ---PVLAAPLLQVPPSPPASPTLQ--------------APRRPPTPGPDTSVSGPRLTLA 875
P +A + QVP SP +S ++Q + R + S + P T+
Sbjct: 1139 SEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMD 1198
Query: 876 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 929
PPPPP LS AG+ S + GY + G A P D
Sbjct: 1199 DMALPPPPP-----ELLSDQQKAGYGGS------HISGYATLRRGPPPAPPKRD 1241
Score = 164 bits (416), Expect = 3e-40
Identities = 172/564 (30%), Positives = 219/564 (38%), Gaps = 118/564 (20%)
Query: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
LE S S+ P SL PPL P + P TAS P +P L PP P P
Sbjct: 587 LEESSKARMESMNRPYTSLV-PPLSPQPKIVTP--YTASQP--SPPLPPPPPPPP----P 637
Query: 572 PPSPLTTPPPETPSSIATPPPQAPPALA--------------SPPLQGLPSPPLSPLATP 617
PP P PPP PS A A P S L P+PP+ +
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697
Query: 618 PPQ--APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA---------LAVHLLQ---- 662
PQ PP +PP PP PP P+P AP+ L +H +Q
Sbjct: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757
Query: 663 -APFSPPPSPPVQAPFSPPASPPV------SPSATPPSQAPPSLAAPPLQVPPSPPASP- 714
AP +PPP PP+ AP PP +PP +P++T + AAPP PP PPA
Sbjct: 758 VAPPTPPPPPPIPAPL-PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
Query: 715 PMSPSATPPPQAP-PPLAAPPLQVPPSPP--ASPPMSP------------SATPPPRVPP 759
P P++ PP P PP+ PP +P A PP SP S PPP PP
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819
+ + PL+ P A PQ+PPA+ P P+S P +P P
Sbjct: 877 AMESQPLKPVP-----------ANVAPQSPPAVKAKP----KWQPSSIPVPSPDFPPPP- 920
Query: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS-VSGPRLTLALAP 878
P S L PPP PV A P PP P ASPT P + +PG TS S P
Sbjct: 921 PESSLVFPPPPPSPVPAPP---PPPPPTASPT---PDKSGSPGKKTSKTSSP-------G 967
Query: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS----PPPDA---- 930
G PPP+ +S++ A H + + L + P + S PPP A
Sbjct: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027
Query: 931 ---ELAACH-PAAWSRG----PAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGP 981
L+ + P +G AP L+ RG P PP+ + P
Sbjct: 1028 GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD---------FPPPPP 1078
Query: 982 ESATPAPGALDPGPSPGTSGGKAA 1005
E+ P P P G + K A
Sbjct: 1079 ETELPLPPIEIPAVFSGNTSPKVA 1102
Score = 140 bits (354), Expect = 5e-33
Identities = 192/768 (25%), Positives = 273/768 (35%), Gaps = 139/768 (18%)
Query: 97 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSA 155
SG + P ++ S G S T G + + + S E RG E ++
Sbjct: 536 SGSSSSSIPESQSNHSNQSDSG-VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKAR 594
Query: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215
+ + R TS P +P P + A+ LP P P P PP P
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP---------- 644
Query: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KP 274
P ++ PSAG S+ T L + ++ + P P SQ KP
Sbjct: 645 --PPPPLPSQSAPSAGSAAPMFVK---YSTITRLQNASQHSGALFKPPTPPVMQSQSVKP 699
Query: 275 KGL----QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330
+ L + PP PP A+ L +P A PS A P P + +
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA-PSLPQFSAPPPPLKIHQVQHITQV 758
Query: 331 LPPSPPLATPLPLAPPSPSAPPS-LQTLPSPPATPP-----SQAPPSMTTPPMQAPPSLQ 384
PP+PP P+P AP P APP L T+P+P +T +QA P TPP+
Sbjct: 759 APPTPPPPPPIP-APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP 817
Query: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
P +P S +P + PP PTL SF P + + S
Sbjct: 818 AFPASYIPPSPPTPPVPVPP----------------PTLPKQQSFCAKPPPSPLSPVPSV 861
Query: 445 SRPAST---PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP-LTIHPLQALSSLASHSP 500
+ ++ PP +PP A S P P + V+P S P + P SS+ SP
Sbjct: 862 VKQIASQFPPPPTPP--AMESQPLKP-----VPANVAPQSPPAVKAKPKWQPSSIPVPSP 914
Query: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
P PP E+ PP PP+ + PP P+ +P P ++ S P +T
Sbjct: 915 DFP-----PPPPESSLVFPPP----PPSPVPAPPPPPPPTASPTPDKSGS-----PGKKT 960
Query: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP--PALASPPLQGLPSPPLSPLATPP 618
+P + PP+P ++ S P P+ P +L S S S PP
Sbjct: 961 SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020
Query: 619 PQAPP--------XLALPPLQAPPSPPASPPL-------SPLATPSPQAPNALAVHLLQA 663
P APP + LP + A P+ S + PSP + +
Sbjct: 1021 PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF------- 1073
Query: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSA 720
PPP P + P P P V T P A P + V +PP + P +
Sbjct: 1074 ---PPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDS 1130
Query: 721 TPPPQA----PPPLAAPPLQVPPSPPASPPMSPS--------------------ATPPPR 756
T QA P +A QVP SP +S + P ++ R
Sbjct: 1131 TRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSR 1190
Query: 757 VPPLLAAPPLQVPPSPPASLP--------------MSPLAKPPPQAPP 790
P + +PP PP L + L + PP APP
Sbjct: 1191 AEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPP 1238
Score = 123 bits (309), Expect = 9e-28
Identities = 155/628 (24%), Positives = 235/628 (37%), Gaps = 79/628 (12%)
Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL---------AERAGGIGGATIPESAPRA 77
P PP P PPPP P L A A P+ + A GA P
Sbjct: 632 PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPV 691
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
++S P P +G PP P P +PG A +P P + S
Sbjct: 692 MQSQSV-----KPQILVPPNGVVPPPPP-----PPPPPTPGSAMAQLKPAPCAPSLPQFS 741
Query: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
A P + PTP P P A A + + PAP++
Sbjct: 742 APP----------PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS- 790
Query: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
T+ V+ A+ + T P P A+++P+ P+ + P + P +
Sbjct: 791 ----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846
Query: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317
A+ P +P P K + + PP TPP ++ P L P+ ++ +A SP KA+P
Sbjct: 847 CAKPPP-SPLSPVPSVVKQIASQFPPPPTPPAMESQP-LKPVPAN-VAPQSPPAVKAKPK 903
Query: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377
P + P P PP P + P PPSP +P+PP PP A P TP
Sbjct: 904 WQPSSIPVPSPDFPPPPPESSLVFPPPPPSP--------VPAPPPPPPPTASP---TPDK 952
Query: 378 QAPPSLQTIPPIQVPHSLTSP-SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
P +T +SP + PP+P SS+++++ P + +S
Sbjct: 953 SGSPGKKT-------SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT 1005
Query: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPA---SPPLQTSLSPAVSPLSSPLTIHPLQALS 493
A SPS+ PP +PP L+L LQ A +P+ S +
Sbjct: 1006 PPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFP 1065
Query: 494 SLASHS---PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL----APPPL 546
S S S P P + L +PP+E + + + +P ++ P + + APPP
Sbjct: 1066 SPPSDSDFPPPPPETELPLPPIEIPAVFSGNT--SPKVAVVNPQPQQWSKMSVKKAPPPT 1123
Query: 547 ---QTASAPLTTPHLETPPCPAPCPLQAPPSP---LTTPP---PETPSSIATPPPQAPPA 597
+ S LT + P A Q P SP L+ P + ++ +
Sbjct: 1124 RPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGS 1183
Query: 598 LASPPLQGLPSPPLSPLATPPPQAPPXL 625
L+S + P+ + +A PPP PP L
Sbjct: 1184 LSSRMSRAEPTATMDDMALPPP--PPEL 1209
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 164 bits (414), Expect = 6e-40
Identities = 285/1101 (25%), Positives = 400/1101 (36%), Gaps = 170/1101 (15%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
AAR P A AP P PG P A + A + K ++A G GA
Sbjct: 2 AARAPPA-APAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAE--P 58
Query: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
+APRA + + A R GRG +A K+ S GP PG A +
Sbjct: 59 AAPRA-------KKAEDKAKRAKGKGRGSAKAENDKHLSVGPGQGPGSAVDEHQDNVFFP 111
Query: 132 KGLRISAEETVARG----KATEAPKRSALSAGA--RRDT-----SGPTPGTPSPAMARRS 180
G EE + ++ + ++ L+ G DT S P + + ++
Sbjct: 112 SGRPPHLEELHTQAQEGLRSLQHQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQT 171
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQR 236
+ E A S R +E ++ S+ H + S + R R S GL +
Sbjct: 172 TSYVAESSTAEDALSIR----SEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQ 227
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
+ L R+ A GTPRAP A+R P V + +
Sbjct: 228 HVQKELG---------LRNEREAPGTPRAPG--------ARDAVRIPTVDGRPRGTSGMG 270
Query: 297 GPLSSSPLATPSPSGTKARP--------VPPPDNAATPLPATLPPSPPLATPLPLAPPS- 347
+S L + +G + V D T +PPL P+ LA P
Sbjct: 271 ARVSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFVGRSTGTR--APPLTRPMSLAVPGL 328
Query: 348 -----PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
P+ P S SP AT S+ P PP +L +L+ SL +
Sbjct: 329 TGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSL----RTLSRCSLHS 384
Query: 403 PPSPLALSSLQATTSLGSPTLQATH---SFLTMSPRQTQASLTSPSRPASTPPDSP--PL 457
SP ++ SL +S+ SP ++ H S T S Q+ ++ S S+ S P
Sbjct: 385 A-SPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPE 443
Query: 458 QAPLSLPASPPLQTSL---SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
+ S PP Q SP+ + +++ L+ S PP
Sbjct: 444 SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRR 503
Query: 515 QSSLAPPSLQTPPASLTTPPL---ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
SL L P L PP + P L PP S APCP
Sbjct: 504 THSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA---------APCP--- 551
Query: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPL-----QGLPSPPLSPLATPPPQAPPXLA 626
P+P + P + PP++P SP G P+ P LA PP A P A
Sbjct: 552 -PNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP--ASPGKA 608
Query: 627 LPP-------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP----FSPPPSPPVQA 675
PP L++P + +S S ++ S AP+ + + P F PP P V A
Sbjct: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668
Query: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
PFSPP S P SP+ P+ A P++ P+ + P SPP TP P +P +
Sbjct: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP-----TPQTTLTPLQESPVI 723
Query: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP--PPQAPPALA 793
SPP SPP PS PP PP P + V + PL P PP PPA
Sbjct: 724 SKDQSPPPSPP--PSYHPP---PPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778
Query: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASP 850
L PP P +A FS ++ P P +P + P +A LQ+ PP SP
Sbjct: 779 EQDLSMADFPP---PEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI--QPPGSP 833
Query: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRSPSSTLSGPDLAGHSS 902
P PP P P +S G +A P P PP + L P L
Sbjct: 834 --DPPPAPPAPAPASSAPG---HVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL---- 884
Query: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP- 961
+ +R G GGA PA P PL R G P P
Sbjct: 885 ------QMVRLRSVGAPGGAPT------------PALGPSAPQKPLR-RALSGRASPVPA 925
Query: 962 PATGPGSADGL--CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019
P++G +A L C++ +EG SA P G + P P S A+ + S + +
Sbjct: 926 PSSGLHAAVRLKACSLAASEGLSSAQP-NGPPEAEPRPPQSPASTASFIFSKGSRKLQLE 984
Query: 1020 ARLGELPLGALQASVVQHLLS 1040
+ LQ ++V L S
Sbjct: 985 RPVSPETQADLQRNLVAELRS 1005
Score = 146 bits (369), Expect = 9e-35
Identities = 229/870 (26%), Positives = 314/870 (36%), Gaps = 154/870 (17%)
Query: 21 APGLLTPRPPGSPR----PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
APG TPR PG+ P P +GA ++ AG A + R
Sbjct: 241 APG--TPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDR 298
Query: 77 AGPT-----RSAGTSSRNPASRPPA---------SGRGERAPPAKNTSPGPVSSPGRASG 122
RS GT + P +RP + +G E PA + SP
Sbjct: 299 VYRDDTFVGRSTGTRAP-PLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPH 357
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR---- 178
P + L + T++R A S S G S P P + P+ +
Sbjct: 358 AVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWS 417
Query: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
S+++ T V + + +EG +S S + +S P R S GG A
Sbjct: 418 HSQSSDTIVS---DGSTLSSKGGSEGQPES--STASNSVVPPPQGGSGRGSPSGGSTAEA 472
Query: 239 SRSLS-SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
S +LS S+ LS + S + P P +GL P PP+ +
Sbjct: 473 SDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQ-- 530
Query: 298 PLSSSPLATPSPSGTKARPVPP-PDNAATP-LPATLPPSPPLATPLPLAPPS-------- 347
P P T G A P PP P N+ P L PP + L+P S
Sbjct: 531 PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590
Query: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP-SLQAPPSP 406
P+ PP + L PPA+P PP + SL++ P V SLTS S + P+P
Sbjct: 591 PTLPP--KGLAGPPASPGKAQPPKP-----ERVTSLRS-PGASVSSSLTSLCSSSSDPAP 642
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
S Q T LG + H P+ PS+P S P +P L AP +P
Sbjct: 643 SDRSGPQILTPLGDRFVIPPH------PKVPAPFSPPPSKPRSPNPAAPALAAPAVVPG- 695
Query: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
P+ T+ SP S P +PQ L+ L P+ ++ PPS P
Sbjct: 696 -PVSTT---DASPQSPP---------------TPQTTLTPLQESPVISKDQSPPPS--PP 734
Query: 527 PASLTTPPLENLPSL---APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
P+ PP P + AP +TA PL P+ PP P P P + S PPPE
Sbjct: 735 PSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW--PPPPPPAPEEQDLSMADFPPPEE 792
Query: 584 PS-SIATPPPQAP---PALASPPLQ-------------GLPSPPLSPLA-TPPPQAPPXL 625
S+A+P P P P L S P G P PP +P A P AP +
Sbjct: 793 AFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHV 852
Query: 626 ALPPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--------PSP 671
A P + P PP +PL TPS + + + AP P P
Sbjct: 853 AKLPQKEPVGCSKGGGPPREDVGAPLVTPS--LLQMVRLRSVGAPGGAPTPALGPSAPQK 910
Query: 672 PVQAPFSPPASPPVSPSATPPSQ---------APPSLAAPPLQVPPSPPASPPMSPSATP 722
P++ S ASP +PS+ + A L++ PP PP SP++T
Sbjct: 911 PLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA 970
Query: 723 P--------------PQAPPPLAAPPLQVPPS--------PPASPPMSPSATPPPRVPPL 760
P +P A + PP +P SP A PP P
Sbjct: 971 SFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS 1030
Query: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790
+ P PP+ P+ PL PP P
Sbjct: 1031 VGVP----PPASPSYPRAEPLTAPPTNGLP 1056
Score = 134 bits (338), Expect = 4e-31
Identities = 238/871 (27%), Positives = 318/871 (36%), Gaps = 178/871 (20%)
Query: 99 RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA---TEAPKRSA 155
R ER P +PG + + RP G R+S + A +A TEA +
Sbjct: 236 RNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRH 295
Query: 156 LSAGARRDTS-GPTPGTPSPAMARRSRAA------GTEVGLP-RPAPSARPR-------- 199
+ R DT G + GT +P + R A G P PA S P+
Sbjct: 296 IDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLI 355
Query: 200 -----PPTEGP----RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL---SSSAT 247
PPT R S+ + S S SPA+ R + P RS SSS T
Sbjct: 356 PHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDT 415
Query: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQA----LRPPQVTPPR--------KDAAPA 295
S + + G+ + S+ +P+ A + PPQ R +A+
Sbjct: 416 WSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDT 475
Query: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLP--ATLPPSPPLATPLPLAPPSPSAPPS 353
L SS L+ S S K + PPP L P PL P P P
Sbjct: 476 LSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLP-----PKPERKQQ 530
Query: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
Q LP PP T S+ + PP P+ +P + S P ++P L+ SS
Sbjct: 531 PQ-LPRPPTTGGSEGAGAAPCPPN---PANSWVPGLSPGGSRRPP--RSPERTLSPSSGY 584
Query: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
++ S G+PTL P + + PP SP + P P TSL
Sbjct: 585 SSQS-GTPTL--------------------PPKGLAGPPASPGK----AQPPKPERVTSL 619
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP----PSLQTPPAS 529
+ +SS LT SS + +P I+ PL + + P P+ +PP S
Sbjct: 620 RSPGASVSSSLT----SLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPS 675
Query: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC--PLQAPP--SPLTTPPPETPS 585
P P+LA P + T ++PP P PLQ P S +PPP P
Sbjct: 676 KPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPP 735
Query: 586 SIATPPP---------QAPPA--LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
S PPP +AP A A PLQ PP PPP AP L PP
Sbjct: 736 SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP------PPPPAPEEQDLSMADFPP 789
Query: 635 ---------SP-PASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQAPFSPPASP 683
SP PA P SP SP A ++ A L +Q P SP P P AP PAS
Sbjct: 790 PEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAP--APASS 847
Query: 684 PVSPSATPPSQAPPSLA---APPLQVPPSPPASPPM----------SPSATPPPQAPPPL 730
A P + P + PP + +P +P + +P P P P
Sbjct: 848 APGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSA 907
Query: 731 AAPPLQVPPSPPASPPMSPS----ATPPPRVPPLLAAPPLQV--PPSPPASLPMSPLAKP 784
PL+ S ASP +PS A + L A+ L P PP + P
Sbjct: 908 PQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR------ 961
Query: 785 PPQAPPALAT-----------------PPLQA---------LPSPPASFPGQAPF-SPSA 817
PPQ+P + A+ P QA L S P QAP SP A
Sbjct: 962 PPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKA 1021
Query: 818 SLPMS---PLATPPPQAPPVLAAPLLQVPPS 845
P++ + PPP +P A L PP+
Sbjct: 1022 PPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052
Score = 134 bits (336), Expect = 6e-31
Identities = 230/891 (25%), Positives = 306/891 (34%), Gaps = 177/891 (19%)
Query: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178
R T RP K + R P+ G R + P GTP
Sbjct: 194 RKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNEREAP--GTP------ 245
Query: 179 RSRAAGTEVGLPRPAPSARPRPPTE-GPRKSVSS--ASEHSTTEPSPAARRRPSAGGGLQ 235
RA G + P RPR + G R S+ + A + E +R
Sbjct: 246 --RAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVYRDD 303
Query: 236 RPASRSLSSSATPLSSPAR------SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
RS + A PL+ P +G + P +PA P+ L L P V PP
Sbjct: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPT 363
Query: 290 KDAAP----ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
D +L LS L + SP+ R + + ++P P + PS T
Sbjct: 364 VDVVALGRCSLRTLSRCSLHSASPASV--RSLGRFSSVSSPQPRSRHPSSSSDTW----- 416
Query: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405
S S T+ S +T S+ P + S +PP Q SPS +
Sbjct: 417 ---SHSQSSDTIVSDGSTLSSKG--GSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAE 471
Query: 406 PLALSSLQATTSLGSPTLQATH-SFLTMSPRQT----QASLTSPSRPASTPPDSPPLQAP 460
S++++ L ++ PR+T Q L P P PP Q P
Sbjct: 472 ASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQP 531
Query: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
LP P S +P + LS S P + P S
Sbjct: 532 -QLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590
Query: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE-----TPPC-----PAPCPLQ 570
P+L PP L PP P A PP L +P T C PAP
Sbjct: 591 PTL--PPKGLAGPPAS--PGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRS 646
Query: 571 APP--SPL-----TTPPPETPSSIATPP--PQAP----PALASPPLQGLPSPPLSPLATP 617
P +PL P P+ P+ + PP P++P PALA+P + +P P + A+P
Sbjct: 647 GPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAV--VPGPVSTTDASP 704
Query: 618 PPQAPPXLALPPLQAPP------SPPASPPLSPLATPSP--------QAPNA--LAVHLL 661
P L PLQ P SPP SPP S P P +AP+A A L
Sbjct: 705 QSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPL 764
Query: 662 QAPFSPPPSPPV-------QAPFSPP-------ASP-PVSPSATPP---SQAPPSLAAPP 703
Q P PPP PP A F PP ASP P PS +P S A S +A
Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA 824
Query: 704 LQV-PPSPPASPPMSPSATPPPQAPPPLA--------------APPLQVPPSPPASPPM- 747
LQ+ PP P PP P+ P AP +A PP + +P +P +
Sbjct: 825 LQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL 884
Query: 748 ---------SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP------------------ 780
+P P P + P PL+ S AS +P
Sbjct: 885 QMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS 944
Query: 781 --LAKPPPQAPPALATPPLQALPSPPASF---------PGQAPFSPSASLPM-------- 821
L+ P PP P Q+ P+ ASF + P SP +
Sbjct: 945 EGLSSAQPNGPPEAEPRPPQS-PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAEL 1003
Query: 822 -SPLATPPPQAP--------PVLAAPLLQVPP-SPPASPTLQAPRRPPTPG 862
S PPQAP PV P + VPP + P+ P + PPT G
Sbjct: 1004 RSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNG 1054
Score = 63.2 bits (152), Expect = 1e-09
Identities = 96/417 (23%), Positives = 136/417 (32%), Gaps = 68/417 (16%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
P + P +P PP PR P P PA LA A G + +++P+
Sbjct: 662 PHPKVPAPFSP-PPSKPRSPNPAAPA---------------LAAPAVVPGPVSTTDASPQ 705
Query: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
+ PT ++ P P + + PP+ S P P + P +
Sbjct: 706 SPPTPQ---TTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEE 762
Query: 137 SAEETVARGKATEAPKRSALSAG-------ARRDTSGPTPGTPS--PAMARRSRAAGTEV 187
++ AP+ LS A + P P PS P + A+ +
Sbjct: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822
Query: 188 GLPRPAPSARPRPPTEGPRKS-VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
+ P P PP P + SSA H P GG + L + +
Sbjct: 823 TALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882
Query: 247 TPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPPQVTPPRKDAAP----ALGPL 299
RS + G P P+ P +P + L P P A A
Sbjct: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942
Query: 300 SSSPLATPSPSGT-KARPVPPPDNAATP----------LPATLPPSPPLATPL------- 341
+S L++ P+G +A P PP A+T L P SP L
Sbjct: 943 ASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAE 1002
Query: 342 ---------PLAPP-SPSAPPSLQTLPS----PPATPPSQAPPSMTTPPMQAPPSLQ 384
P AP SP APP + PS PPA+P +T PP P Q
Sbjct: 1003 LRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQ 1059
Score = 41.6 bits (96), Expect = 0.004
Identities = 68/268 (25%), Positives = 89/268 (33%), Gaps = 53/268 (19%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
AA + +A A + P P P PP PA+ A G V + P E G G P
Sbjct: 816 AASSSSATALQIQPPGSPDPPPAPPAPAPAS----SAPGHVAKLPQKEPVGCSKGGGPPR 871
Query: 73 ---SAPRAGPT-------RSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
AP P+ RS G P PA G P + SG
Sbjct: 872 EDVGAPLVTPSLLQMVRLRSVGAPGGAPT---PALGPSAPQKPLRRA----------LSG 918
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
P P GL R KA LS+ +GP P P + S A
Sbjct: 919 RASPVPAPSSGL-----HAAVRLKACSLAASEGLSSA---QPNGPPEAEPRPPQSPASTA 970
Query: 183 A------GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA------ 230
+ ++ L RP P + R V+ S P A ++ P A
Sbjct: 971 SFIFSKGSRKLQLERP---VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVAR 1027
Query: 231 --GGGLQRPASRSLSSSATPLSSPARSG 256
G+ PAS S A PL++P +G
Sbjct: 1028 KPSVGVPPPASPSY-PRAEPLTAPPTNG 1054
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 162 bits (410), Expect = 2e-39
Identities = 223/886 (25%), Positives = 309/886 (34%), Gaps = 160/886 (18%)
Query: 81 RSAGTSSRNPASRPPASGRGER-----APPAK--NTSPGPVSSPGRASGTTRPGPLGQKG 133
RSA S R A R GRG + PP + + +P P +P R G G +
Sbjct: 138 RSALRSQRGRAPR----GRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEE-----GTER 188
Query: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA---AGTEVGLP 190
+ + E + R +A +AP+ A R + G PG P+ R+ +A A V +P
Sbjct: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
Query: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-------------GGGLQ-- 235
+P P PP + S P P RR GGGL
Sbjct: 249 KPEPP----PPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFV 304
Query: 236 -RPASRSLSSSATPLSSPARSG-------------PSARGTPRAPAHPSQPKPKGLQALR 281
+ SR+ LS SG P R P K + Q L
Sbjct: 305 IKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQE--QKLD 362
Query: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
+ ++ G + P + A P P PP+P + P
Sbjct: 363 DEEEEKKEEEEKDKEGEEKEERAVAE-----EMMPAAEKEEAKLPPPPLTPPAP--SPPP 415
Query: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
PL PPS S PP L PP PP PP + PP A + PP VP + + +
Sbjct: 416 PLPPPSTSPPPPL----CPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGR 471
Query: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
P +P + +A + P T +PS PP+ P AP
Sbjct: 472 PPLTPSQRAEREAARA---------------GPEGTSPPTPTPSTATGGPPEDSPTVAPK 516
Query: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
S ++ + P VS SS + P + + P+ +S ++ PP+ T P
Sbjct: 517 STTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS-----P 571
Query: 522 SLQTPPASLTTPPLENLPSLAPPPL-QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP 580
+ PA + +PP P P PL + + L P + PP P PP
Sbjct: 572 PVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRW----TSLTRELPPPPPAPPP 627
Query: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
P PS PP AP + PL L +P +P L PPL AP +P P
Sbjct: 628 PPAPS-----PPPAPATSSRRPLL-LRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
Query: 641 PLSPLATPSPQAPNALAV----HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
P A SP P AV HL F+P + PV+A SP +P +S
Sbjct: 682 ---PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG-------- 730
Query: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
P A LQ P + P A PPPQ P LQ PPSP PP+ +
Sbjct: 731 PQTQAQLLQ--PLQALQTQLLPQALPPPQ-------PQLQPPPSPQQMPPLEKARI---- 777
Query: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
A + PL+ + L +Q Q +
Sbjct: 778 -----------------AGVGSLPLSGVEEKMFSLLKRAKVQLF-----KIDQQQQQKVA 815
Query: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR----- 871
AS+P+SP A V + P +++A R P+ GP++ V GPR
Sbjct: 816 ASMPLSPGGQMEEVAGAV--KQISDRGPVRSEDESVEAKRERPS-GPESPVQGPRIKHVC 872
Query: 872 ------LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
L A A P P S DLA +S+ S E +
Sbjct: 873 RHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESV 918
Score = 104 bits (259), Expect = 5e-22
Identities = 104/385 (27%), Positives = 137/385 (35%), Gaps = 76/385 (19%)
Query: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP-----PQAPPPLAAPPLQVPP 739
V+ P ++ + PP PP+P PP+ P +T P P PPP++ PPL PP
Sbjct: 386 VAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP 445
Query: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799
PPA S PP V P + PP P+ A+ P+ P A
Sbjct: 446 PPPAQEEQEES---PPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTA 502
Query: 800 LPSPPASFPGQAPFS-------------------------PSASLPMSPLATPPPQAPPV 834
PP P AP S P + P P + PV
Sbjct: 503 TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPV 562
Query: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR---------------LTLAL--- 876
L P+ PP P + +P R PTP P T V P LT L
Sbjct: 563 LRPPITTSPPVPQEPAPVPSPPRAPTP-PSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
Query: 877 APGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDS---GPEGGAAASP---P 927
P PPPPP+ SP +T S L + T + L+ Y+S P GA +P P
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
Query: 928 PDAELAACHPAAWSRGPAPPLAF-RGAPGAPLPWPPATGPGSADGLCTIYETEG------ 980
P A+ + P + G L+ R AP P P A L +T+
Sbjct: 682 PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
Query: 981 --------PESATPAPGALDPGPSP 997
P++ P L P PSP
Sbjct: 742 QALQTQLLPQALPPPQPQLQPPPSP 766
Score = 101 bits (252), Expect = 3e-21
Identities = 175/704 (24%), Positives = 241/704 (34%), Gaps = 121/704 (17%)
Query: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LSSPARS 255
RP P E P + +A E+ T SPA P GG P + P SP ++
Sbjct: 1784 RPWGPREEPAH-LEAAEENQTIVHSPAPSSEPP--GGEDPPLDTDVLVPGAPERHSPIQN 1840
Query: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
A P P+ ++ P +P R+ LG +S PL +P +
Sbjct: 1841 LDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRP----LGGVSFGPLPSPGSPSSLTH 1896
Query: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
+P + P P P P P PPS A P L+T P PP+ ++T
Sbjct: 1897 HIPTVGDPDFPAPPRRSRRPSPLAPRP--PPSRWASPPLKTSPQLRVPPPTSVVTALT-- 1952
Query: 376 PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS----SLQATTSLGSPTLQATHSFLT 431
P S + PP P +PP P L ++ + L + L S L
Sbjct: 1953 ----PTSGELAPPGPAP---------SPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLG 1999
Query: 432 MSPRQTQ-----ASLTSPSRPA-STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
P Q + A +S P S+ +S P + P + L+P+ +P +P
Sbjct: 2000 TEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATP-GAPR- 2057
Query: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
++ L + + E ++ P TPP+ P +
Sbjct: 2058 ---IEQLDGVDDGTDS-----------EAEAVQQPRGQGTPPSG---------PGVVRAG 2094
Query: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605
+ A+ P + P L+ P S+ PP P A S P QG
Sbjct: 2095 VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESL---PPAPPLANGSQPSQG 2151
Query: 606 LPSPPLSPLAT----PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA-VHL 660
L + P P T P L+L P PP P AT N L V +
Sbjct: 2152 LTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKP---------ATSKIILVNKLGQVFV 2202
Query: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
A P PPV+ PP P +SP+A PP P L V P P A
Sbjct: 2203 KMAGEGEPVPPPVK---QPPLPPTISPTAPTSWTLPPG---PLLGVLPVVGVVRP----A 2252
Query: 721 TPPPQAPPPLAAPPLQVPPSPPASPP--------MSPSATPPPRVPPLLAAPPLQVPPSP 772
PPP PPPL V S PASPP +S + P PP AP L
Sbjct: 2253 PPPP--PPPLTL----VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEA 2306
Query: 773 PASLPMSPLAKPPPQAPPALATPPLQAL-----PSPPASFPGQAPFSPSASLPMSPLATP 827
P P + + TP ++ + P PA P + L P P
Sbjct: 2307 SEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGP 2366
Query: 828 P--PQAPPVL------------AAPLLQVPPSPPASPTLQAPRR 857
P P PP L A+ + PPSP QAP+R
Sbjct: 2367 PQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKEN-QAPKR 2409
Score = 80.1 bits (196), Expect = 1e-14
Identities = 77/274 (28%), Positives = 100/274 (36%), Gaps = 40/274 (14%)
Query: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
PA+ PPP PP + PP P PP++ P PL PPP P ++ PPL + P
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPP---PLPPPSTSPPPPLCPPPP---PPVSPPPLPSPP 445
Query: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
PPA + SP PPV+ A + PP +P+ +A R
Sbjct: 446 PPPAQEEQEE----------SP--------PPVVPATCSRKRGRPPLTPSQRAEREAARA 487
Query: 862 GPDTSVSGPRLTLALAPGPPPP--PSRSPSST--------LSGPDLAGHSSSATSTPEEL 911
GP+ S P T + A G PP P+ +P ST P ++ SS TP
Sbjct: 488 GPE-GTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
Query: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSAD 970
D SP + P P P P P P+P P +
Sbjct: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
Query: 971 GL----CTIYETEGPESATPAPGALDPGPSPGTS 1000
E P A P P A P P+P TS
Sbjct: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS 640
Score = 77.8 bits (190), Expect = 5e-14
Identities = 151/630 (23%), Positives = 205/630 (32%), Gaps = 167/630 (26%)
Query: 436 QTQASLTSPSRPASTPP--DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
+ Q + SP+ P+S PP + PPL + +P +P
Sbjct: 1800 ENQTIVHSPA-PSSEPPGGEDPPLDTDVLVPGAPE------------------------- 1833
Query: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPS---------LQTPPASLTTPPLENLPSLAPP 544
HSP L PPL S APP ++ P S + PL + S P
Sbjct: 1834 ---RHSPIQNLD----PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGV-SFGPL 1885
Query: 545 PLQTASAPLT--TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
P + + LT P + P PAP PSPL PP PS A+PP + P L PP
Sbjct: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP--PSRWASPPLKTSPQLRVPP 1943
Query: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP------LATPSPQAPNAL 656
P + P L P PSPP L P + + A
Sbjct: 1944 ----------PTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDF 1993
Query: 657 AVHLLQA-PF------------------------SPPPSPPVQAPFSPPASPPVSPSATP 691
A LL PF S P S + P + ++P ++PSATP
Sbjct: 1994 AASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATP 2053
Query: 692 PSQAPPSL---------AAPPLQVPP---SPPASPPM---------SPSATPPPQAPPPL 730
+ L A +Q P +PP+ P + A PP P +
Sbjct: 2054 GAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEI 2113
Query: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS-------LPMSP--- 780
L+ P + PP P + P Q + PA LP +P
Sbjct: 2114 VDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVR 2173
Query: 781 -LAKPPPQAPPALATPPL---------------QALPSPPASFPGQAPFSPSASLPMSPL 824
L+ P PP AT + + P PP P + P P P +P
Sbjct: 2174 VLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP---PVKQPPLPPTISPTAPT 2230
Query: 825 ATPPPQAPPVLAAPLLQV---PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881
+ P P + P++ V P PP P P P ++ R++ PP
Sbjct: 2231 SWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP 2290
Query: 882 -PPPSRSPSSTLSG------PDLAGHSSSA-------TSTPEELRGYDSGPEGGAAASPP 927
PPP ++P G P + G S T T + D E SP
Sbjct: 2291 APPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPG 2350
Query: 928 PDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
P E R P PL G P P
Sbjct: 2351 PLQE----------RSPLLPLPEDGPPQVP 2370
Score = 76.3 bits (186), Expect = 2e-13
Identities = 127/509 (24%), Positives = 169/509 (33%), Gaps = 93/509 (18%)
Query: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA--SAPLTTPHLETPPCP--- 564
PPL+T + + P PPL APPP + A + P+ P
Sbjct: 1820 PPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGG 1879
Query: 565 ---APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
P P PS LT P ++ P APP + P SPLA PP
Sbjct: 1880 VSFGPLPSPGSPSSLTHHIP----TVGDPDFPAPPRRSRRP---------SPLAPRPP-- 1924
Query: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
P A PPL+ P PP S + +P + AP P PSPP P
Sbjct: 1925 PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL-------APPGPAPSPPPPEDLGPDF 1977
Query: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPP---ASPPMSPSATPPPQAPPPLAAPP---L 735
S S A AA L P A+ M S P + ++P +
Sbjct: 1978 EDMEVVSGL--SAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
Query: 736 QVPPSPPASPPMSPSATP-PPRVPPL-------------LAAPPLQ-VPPSPPASLPMSP 780
P + ++P ++PSATP PR+ L + P Q PPS P +
Sbjct: 2036 HFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGV 2095
Query: 781 L------AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 834
L A+PP P + L+ L P G SLP +P Q
Sbjct: 2096 LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR----EESLPPAPPLANGSQPSQG 2151
Query: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 894
L A PA PT P PG L+ GP P P + +S +
Sbjct: 2152 LTAS--------PADPTRTFAWLPGAPG----------VRVLSLGPAPEPPKPATSKIIL 2193
Query: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954
+ G + E P PP ++ P +W+ P P L
Sbjct: 2194 VNKLGQVFVKMAGEGE-------PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVV 2246
Query: 955 GAPLPWPPATGPGSADGLCTIYETEGPES 983
G P PP P T+ + GP S
Sbjct: 2247 GVVRPAPPPPPPP-----LTLVLSSGPAS 2270
Score = 75.1 bits (183), Expect = 3e-13
Identities = 99/365 (27%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 717 SPSATPPPQAPPPLAAPPLQVPPSPPA-------SPPMSP-SATPPPRVPPLLAAPPLQV 768
+PS+ PP PPL L VP +P PP+ P S + PP P + ++V
Sbjct: 1809 APSSEPPGGEDPPLDTDVL-VPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKV 1867
Query: 769 PPSPPASLPMSPLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
P P+ P+ ++ P +P P+ T + + P P P S SPLA
Sbjct: 1868 PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDP------DFPAPPRRSRRPSPLAP 1921
Query: 827 PPPQA----PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
PP + PP+ +P L+VPP PT PT G + + GP AP PPP
Sbjct: 1922 RPPPSRWASPPLKTSPQLRVPP-----PTSVVTALTPTSG-ELAPPGP------APSPPP 1969
Query: 883 PPSRSPS-------STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935
P P S LS DL +S + P + +G G + P +E +
Sbjct: 1970 PEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES- 2028
Query: 936 HPAAWSRGPAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
+ SR P+ APG AP P A DG+ ++E E+ G P
Sbjct: 2029 --SPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA-EAVQQPRGQGTPP 2085
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 1054
PG +A AG +R P+ L + +V +L G G
Sbjct: 2086 SGPGVV--RAGVLGAAGDRARPPED----------LPSEIVDFVLKNL-------GGPGD 2126
Query: 1055 SGGGP 1059
G GP
Sbjct: 2127 GGAGP 2131
Score = 71.6 bits (174), Expect = 4e-12
Identities = 117/442 (26%), Positives = 154/442 (34%), Gaps = 75/442 (16%)
Query: 4 KRDKAKAGAAARTPAARAPG------LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP 57
++++AK TP A +P +P PP P PPPPV+P L + P
Sbjct: 395 EKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL------PSPPPPP 448
Query: 58 LAERAGGIGGATIPE--SAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPV 114
E +P S R P + + A+R G P P+ T P
Sbjct: 449 AQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPE 508
Query: 115 SSPGRASGTTRPGPLGQKGLR--ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
SP A +T K +R I + + + P+R D P
Sbjct: 509 DSPTVAPKST----TFLKNIRQFIMPVVSARSSRVIKTPRRF-----MDEDPPKPPKVEV 559
Query: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
SP + + P P PS PR PT ST P P RR
Sbjct: 560 SPVLRPPITTSPPVPQEPAPVPSP-PRAPT-----------PPSTPVPLPEKRR-----S 602
Query: 233 GLQRPASRSLS-SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
L+ P R S + P PA P A P APA S+ +P LR PQ TP
Sbjct: 603 ILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSR-RP---LLLRAPQFTPSEAH 658
Query: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP--------ATLPPSPPLATPLPL 343
L+ PL +P + P P D+ A P P +LP P+ T
Sbjct: 659 LKIYESVLTPPPLG--APEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVK 716
Query: 344 APPSPSAPPSLQTLPSPPA--TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
A SP P+L P A P QA + P Q +PP Q P LQ
Sbjct: 717 AEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLP--------QALPPPQ-------PQLQ 761
Query: 402 APPSPLALSSLQATTSLGSPTL 423
PPSP + L+ G +L
Sbjct: 762 PPPSPQQMPPLEKARIAGVGSL 783
Score = 48.1 bits (113), Expect = 5e-05
Identities = 95/343 (27%), Positives = 118/343 (34%), Gaps = 65/343 (18%)
Query: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP----------LAERAGGIG-G 67
+ A + PR G+P P V A VLGAAG R P + + GG G G
Sbjct: 2070 SEAEAVQQPRGQGTPPSGPGVVRAG--VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDG 2127
Query: 68 ATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRG----ERAPPAKNTSPGPVSSPGR-- 119
P ES P A P + S+ + P R AP + S GP P +
Sbjct: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187
Query: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
S LGQ ++++ E + P +S A TS P P P +
Sbjct: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA--PTSWTLP--PGPLL--- 2240
Query: 180 SRAAGTEVGLPRPAPSARPRP--------PTEGPR-----KSVSSASEHSTTEPSPAARR 226
VG+ RPAP P P P PR K VS+ S S P P
Sbjct: 2241 --GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP 2298
Query: 227 RPSAGGGL-----QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
R G Q P S S + +P G P PA P P LQ
Sbjct: 2299 RLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGP--LQERS 2356
Query: 282 P----PQVTPPR-KDAAPAL----------GPLSSSPLATPSP 309
P P+ PP+ D P L G SSS PSP
Sbjct: 2357 PLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
Score = 34.7 bits (78), Expect = 0.52
Identities = 31/109 (28%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
Query: 101 ERAPPAKNTSPGPVSSPG----RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
+ +P A PGP G R PGP Q L + AR + P
Sbjct: 1033 DESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSL---LQRKSARRCVKQRPSYDIF 1089
Query: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
+ GP P+P RR E+ LP P +RPR PT P
Sbjct: 1090 EDSDDSEPGGP----PAP---RRRTPRENELPLPEPEEQSRPRKPTLQP 1131
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 155 bits (391), Expect = 3e-37
Identities = 186/718 (25%), Positives = 258/718 (35%), Gaps = 86/718 (11%)
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA---SGTTRPGPLGQKGLRISAEET 141
+ S + + P + E+ P + S GR+ G++ P + Q S
Sbjct: 77 SESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY 136
Query: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPA---MARRSRAAGTEVGLPRPAPSARP 198
++ S LS G R P PSP R A E P PS P
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE-----PHPSVTP 191
Query: 199 ---RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
P E P + A + P P + P GG+ S +
Sbjct: 192 TGYHAPMEPPTSRMFQAPPGA---PPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS-PSGTKA 314
G P P S G +PP TP P+ P ++ P TP+ P
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPP-TTPVGGGNLPSAPPPANFPHVTPNLPPPPAL 307
Query: 315 RPV-----PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
RP+ PP A PLP LP + + PP P P+L PSP + PP+ +
Sbjct: 308 RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA--PSPHSLPPASS- 364
Query: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
S PPM+ P S + S +S S A P P + + S PT + S
Sbjct: 365 -SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT---SLSV 420
Query: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
P+ TQ SL S + + PP PP L+ + P P + T HP
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP-----GPFPPSTGAQSTAHP- 474
Query: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
+S+ H Q + Q + PP P P PL+
Sbjct: 475 -PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-----------PGAFPHPLEGG 522
Query: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
S+ P+ +P + P PP P PPP + S + P PP +S S
Sbjct: 523 SSHHAHPYAMSPSLGSLRPY--PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Query: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
P + P P P A P PP P + + L+T ++ A + +P PPP
Sbjct: 581 GSYPCSHPSPSQGPQGA--PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
Query: 670 --------------SPPVQAPFSPPA----SPP----VSPSATPPSQAPPSLAAPPLQVP 707
+PP P SPP+ +PP SP A P + P S P +
Sbjct: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPG 695
Query: 708 PSPPASPPMSPSATPPPQAP---PPLAAPPLQVPPSPPASPPMSP-----SATPPPRV 757
P PPA P PS PPP AP PPL+A ++ P+ P SP S +PPP+V
Sbjct: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKV 753
Score = 139 bits (349), Expect = 2e-32
Identities = 202/788 (25%), Positives = 273/788 (34%), Gaps = 95/788 (12%)
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATP 248
PR +R R G S S + + + AR ++ + + S +S S +
Sbjct: 23 PREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESE 82
Query: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR------KDAAPALGPLSSS 302
++ + + + PR P PS ++L + PR + +P++ S
Sbjct: 83 ETNAPKKTKTEQELPR-PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSV 141
Query: 303 PLATPSPSGTK---ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
+ S SG ARP PP PL PPSP P S P
Sbjct: 142 ENDSDSSSGLSQGPARPYHPP---------------------PLFPPSPQPPDSTPRQPE 180
Query: 360 PPATPPSQAPPSMTTPPMQAPPS--LQTIPPIQVPHSLTSPS-----LQAPPSPLALSSL 412
P P+ PM+ P S Q P PH P L PP +
Sbjct: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP--MGPKGG 238
Query: 413 QATTSLGSPTLQATHSFLT--MSPRQTQASLTSPSRPASTPPDS-------PPLQAPLSL 463
A +S+G P H T +S + AS P++P +TP PP P
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT 298
Query: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH--SPQAPLSSL--IMPPLETQSSLA 519
P PP PA+ PL++ P L H SP A + + P E +LA
Sbjct: 299 PNLPP-----PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 520 PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579
P PPAS + P + +A+A ++ + P P P P + P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 580 PPETPSSIATPPPQAPPALASPPL--QGLPSPP------LSPLATPPPQAPPXLALPPLQ 631
PP + S PP P+L S + QG P PP + A P P P A
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
Query: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691
P S Q PPP P +S P A
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
Query: 692 PS--------QAPPSLAAPPLQVPPSP--PASPPMSPSATP---------PPQAPPPLAA 732
PS P L P QV S P PP+S S+ P P P
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG 593
Query: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
P P PP + SAT + + ++P SPP P A P P A
Sbjct: 594 PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSPGAYKT- 651
Query: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852
ATPP SPP+ G P S P P T P +P V PL P P P+L
Sbjct: 652 ATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPL--PPAGPSGLPSL 708
Query: 853 QAPRRPPTPGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 909
P P GP S + + A P P PP+RSPS D+ H+S + +
Sbjct: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNK 768
Query: 910 EL-RGYDS 916
L RG++S
Sbjct: 769 HLDRGFNS 776
Score = 122 bits (305), Expect = 2e-27
Identities = 170/639 (26%), Positives = 227/639 (35%), Gaps = 126/639 (19%)
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAP--LSSLIMPPLETQSSLAPPSLQTPPASLT 531
S +S S T P + + PQ+P L SL L S P + S +
Sbjct: 73 SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTS 132
Query: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP---PETPSSIA 588
PS+ P + ++ + P P P PPSP PP P P +
Sbjct: 133 -------PSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP--QPPDSTPRQPEASF 183
Query: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP----ASPPLSP 644
P P P P++ PP S + PP APP P Q P + PP+ P
Sbjct: 184 EPHPSVTPTGYHAPME----PPTSRMFQAPPGAPP----PHPQLYPGGTGGVLSGPPMGP 235
Query: 645 L---ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-----PPASPPVSP-------SA 689
A S PN H PPP+ P+ S PP PP +P SA
Sbjct: 236 KGGGAASSVGGPNGGKQH-------PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288
Query: 690 TPPSQAP---PSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVPPSPPA 743
PP+ P P+L PP P + ++ P A P P +P + +PP P
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
P ++PS P APP++ P S +S + + + A P QALPS
Sbjct: 349 GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSY 408
Query: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL--QVPPSPPASPTLQAPRR---- 857
P SFP P SL +S PP P L + + Q PP PP L A
Sbjct: 409 PHSFP------PPTSLSVS--NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460
Query: 858 --PPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPSSTL 892
PP+ G ++ P T PPPP P
Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL--------------AACHPA 938
G H + + + LR Y GP A PPP +++ ++ +
Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576
Query: 939 AWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGALDPG 994
+ S+G P P +G GAP P+PP T S+ L T+ T S A PG
Sbjct: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTASPPG 635
Query: 995 PSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 1026
P P GK A GA G SP R G P
Sbjct: 636 PPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
Score = 117 bits (294), Expect = 5e-26
Identities = 169/672 (25%), Positives = 224/672 (33%), Gaps = 87/672 (12%)
Query: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
T L P SP L SL + + + R T S+ SP + S
Sbjct: 92 TEQELPRPQSPSDLDSLDGRSLNDDGSSDPRD--IDQDNRSTSPSIYSPGSVENDSDSSS 149
Query: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS-SLIMPPLET 514
L + P PP P P P P Q +S H P M P +
Sbjct: 150 GLSQGPARPYHPP------PLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTS 203
Query: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT----ASAPLTTPH--LETPPCPAPCP 568
+ APP PP P L+ PP+ A++ + P+ + PP P
Sbjct: 204 RMFQAPPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPIS 261
Query: 569 LQ------APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
+ APP T PP TP P PPA LP PP +P
Sbjct: 262 VSSSGASGAPP----TKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317
Query: 623 PXLALPPLQAP-PSP----------PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
P L PL PSP P P P PSP H L S P+P
Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP--------HSLPPASSSAPAP 369
Query: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
P++ P+S +S + S++ S + + P Q PS P S PPP +
Sbjct: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS-------FPPPTSLSVSN 422
Query: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP------ 785
PP PS P+ S PPP LLA P PP++ S A PP
Sbjct: 423 QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST-AHPPVSTHHH 481
Query: 786 ------------PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP- 832
Q + P PP +FP P +S P A P
Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH--PLEGGSSHHAHPYAMSPSLGSL 539
Query: 833 -PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
P P PP S + P PP S S + P P PS+ P
Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST--SQGSYPCSHPSPSQGPQGA 597
Query: 892 -LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
P + ++S+ + + S P G ASPP P+ + A P +
Sbjct: 598 PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657
Query: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP--GTSGGKAAAGA 1008
+ PG+P P+ G+ G GP + P + PGP P G SG +
Sbjct: 658 K--PGSP----PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
Query: 1009 GAGASSRSPKQA 1020
A +S P A
Sbjct: 712 PAAPASGPPLSA 723
Score = 94.0 bits (232), Expect = 7e-19
Identities = 143/557 (25%), Positives = 198/557 (35%), Gaps = 58/557 (10%)
Query: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
P G + PPP TP ++ GA+GA KP +GG +P + P A
Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKP---PTTPVGGGNLPSAPPPANFPHVTPNLPP 303
Query: 89 NPASRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
PA RP AS G A P P P + G+ G PGP +KG T+A
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAP 354
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
+ P S+ A R + + S A A S ++ + P PA A P P
Sbjct: 355 SPHSLPPASSSAPAPPMRFPY--SSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 205 PRKSVSSASEH--STTEPSPAARRRPSAGGGLQRPASRSL-SSSATPLSSPARSGPSARG 261
P + S S T+PS ++ S G P R L +S+A P P +G +
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
P H + + Q + Q ++ GP P G+ P
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP--- 529
Query: 322 NAATPLPATLPPSPPLATPLPLAPP---------SPSAPPSLQTLPSPPATPPSQAPPSM 372
A +P +L P PP P L PP P+ PP + S +T P S
Sbjct: 530 YAMSPSLGSLRPYPP--GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH 587
Query: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
+P + PP+ ++T+ S ++S A SP +
Sbjct: 588 PSPSQGPQGAPYPFPPVP---TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 433 SPRQTQASLTSPSRPASTP---PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
SP + + +P S P +PP S PA P SP V P PL
Sbjct: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP--GPLPPAGP 702
Query: 490 QALSSLASHSPQAPLSSLIMPPLE-TQSSLAP------PSLQTPPASLTTPPLENLPSLA 542
L SL P AP S PPL TQ P P PPA +PP P +
Sbjct: 703 SGLPSLPP-PPAAPASG---PPLSATQIKQEPAEEYETPESPVPPARSPSPP----PKVV 754
Query: 543 PPPLQTASAPLTTPHLE 559
P + + HL+
Sbjct: 755 DVPSHASQSARFNKHLD 771
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/223 (27%), Positives = 77/223 (34%), Gaps = 20/223 (8%)
Query: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
P A +P L L P PPG PPP + + G G P + +T S
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVSSSSNSSSSTSQGSY 583
Query: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQK 132
P + P+ S G P PP + SSP + PG P G++
Sbjct: 584 PCSHPSPSQGPQGA-PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 133 GLRISAEETVARG--KATEAPKRSALSAGARRDTSGPT-PGT---PSPAMARRSRAAGTE 186
A +T K P + R TS P PGT SP +
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
Query: 187 VGLPR-PAPSARPR--PPTEGPRKSVSSASEHSTTE-PSPAAR 225
GLP P P A P PP + A E+ T E P P AR
Sbjct: 703 SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 155 bits (391), Expect = 3e-37
Identities = 186/718 (25%), Positives = 258/718 (35%), Gaps = 86/718 (11%)
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA---SGTTRPGPLGQKGLRISAEET 141
+ S + + P + E+ P + S GR+ G++ P + Q S
Sbjct: 77 SESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY 136
Query: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPA---MARRSRAAGTEVGLPRPAPSARP 198
++ S LS G R P PSP R A E P PS P
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE-----PHPSVTP 191
Query: 199 ---RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
P E P + A + P P + P GG+ S +
Sbjct: 192 TGYHAPMEPPTSRMFQAPPGA---PPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS-PSGTKA 314
G P P S G +PP TP P+ P ++ P TP+ P
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPP-TTPVGGGNLPSAPPPANFPHVTPNLPPPPAL 307
Query: 315 RPV-----PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
RP+ PP A PLP LP + + PP P P+L PSP + PP+ +
Sbjct: 308 RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA--PSPHSLPPASS- 364
Query: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
S PPM+ P S + S +S S A P P + + S PT + S
Sbjct: 365 -SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT---SLSV 420
Query: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
P+ TQ SL S + + PP PP L+ + P P + T HP
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP-----GPFPPSTGAQSTAHP- 474
Query: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
+S+ H Q + Q + PP P P PL+
Sbjct: 475 -PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-----------PGAFPHPLEGG 522
Query: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
S+ P+ +P + P PP P PPP + S + P PP +S S
Sbjct: 523 SSHHAHPYAMSPSLGSLRPY--PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Query: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
P + P P P A P PP P + + L+T ++ A + +P PPP
Sbjct: 581 GSYPCSHPSPSQGPQGA--PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
Query: 670 --------------SPPVQAPFSPPA----SPP----VSPSATPPSQAPPSLAAPPLQVP 707
+PP P SPP+ +PP SP A P + P S P +
Sbjct: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPG 695
Query: 708 PSPPASPPMSPSATPPPQAP---PPLAAPPLQVPPSPPASPPMSP-----SATPPPRV 757
P PPA P PS PPP AP PPL+A ++ P+ P SP S +PPP+V
Sbjct: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKV 753
Score = 139 bits (349), Expect = 2e-32
Identities = 202/788 (25%), Positives = 273/788 (34%), Gaps = 95/788 (12%)
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATP 248
PR +R R G S S + + + AR ++ + + S +S S +
Sbjct: 23 PREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESE 82
Query: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR------KDAAPALGPLSSS 302
++ + + + PR P PS ++L + PR + +P++ S
Sbjct: 83 ETNAPKKTKTEQELPR-PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSV 141
Query: 303 PLATPSPSGTK---ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
+ S SG ARP PP PL PPSP P S P
Sbjct: 142 ENDSDSSSGLSQGPARPYHPP---------------------PLFPPSPQPPDSTPRQPE 180
Query: 360 PPATPPSQAPPSMTTPPMQAPPS--LQTIPPIQVPHSLTSPS-----LQAPPSPLALSSL 412
P P+ PM+ P S Q P PH P L PP +
Sbjct: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP--MGPKGG 238
Query: 413 QATTSLGSPTLQATHSFLT--MSPRQTQASLTSPSRPASTPPDS-------PPLQAPLSL 463
A +S+G P H T +S + AS P++P +TP PP P
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT 298
Query: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH--SPQAPLSSL--IMPPLETQSSLA 519
P PP PA+ PL++ P L H SP A + + P E +LA
Sbjct: 299 PNLPP-----PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 520 PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579
P PPAS + P + +A+A ++ + P P P P + P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 580 PPETPSSIATPPPQAPPALASPPL--QGLPSPP------LSPLATPPPQAPPXLALPPLQ 631
PP + S PP P+L S + QG P PP + A P P P A
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
Query: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691
P S Q PPP P +S P A
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
Query: 692 PS--------QAPPSLAAPPLQVPPSP--PASPPMSPSATP---------PPQAPPPLAA 732
PS P L P QV S P PP+S S+ P P P
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG 593
Query: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
P P PP + SAT + + ++P SPP P A P P A
Sbjct: 594 PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSPGAYKT- 651
Query: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852
ATPP SPP+ G P S P P T P +P V PL P P P+L
Sbjct: 652 ATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPL--PPAGPSGLPSL 708
Query: 853 QAPRRPPTPGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 909
P P GP S + + A P P PP+RSPS D+ H+S + +
Sbjct: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNK 768
Query: 910 EL-RGYDS 916
L RG++S
Sbjct: 769 HLDRGFNS 776
Score = 122 bits (305), Expect = 2e-27
Identities = 170/639 (26%), Positives = 227/639 (35%), Gaps = 126/639 (19%)
Query: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAP--LSSLIMPPLETQSSLAPPSLQTPPASLT 531
S +S S T P + + PQ+P L SL L S P + S +
Sbjct: 73 SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTS 132
Query: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP---PETPSSIA 588
PS+ P + ++ + P P P PPSP PP P P +
Sbjct: 133 -------PSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP--QPPDSTPRQPEASF 183
Query: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP----ASPPLSP 644
P P P P++ PP S + PP APP P Q P + PP+ P
Sbjct: 184 EPHPSVTPTGYHAPME----PPTSRMFQAPPGAPP----PHPQLYPGGTGGVLSGPPMGP 235
Query: 645 L---ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-----PPASPPVSP-------SA 689
A S PN H PPP+ P+ S PP PP +P SA
Sbjct: 236 KGGGAASSVGGPNGGKQH-------PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288
Query: 690 TPPSQAP---PSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVPPSPPA 743
PP+ P P+L PP P + ++ P A P P +P + +PP P
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
P ++PS P APP++ P S +S + + + A P QALPS
Sbjct: 349 GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSY 408
Query: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL--QVPPSPPASPTLQAPRR---- 857
P SFP P SL +S PP P L + + Q PP PP L A
Sbjct: 409 PHSFP------PPTSLSVS--NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460
Query: 858 --PPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPSSTL 892
PP+ G ++ P T PPPP P
Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL--------------AACHPA 938
G H + + + LR Y GP A PPP +++ ++ +
Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576
Query: 939 AWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGALDPG 994
+ S+G P P +G GAP P+PP T S+ L T+ T S A PG
Sbjct: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTASPPG 635
Query: 995 PSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 1026
P P GK A GA G SP R G P
Sbjct: 636 PPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
Score = 117 bits (294), Expect = 5e-26
Identities = 169/672 (25%), Positives = 224/672 (33%), Gaps = 87/672 (12%)
Query: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
T L P SP L SL + + + R T S+ SP + S
Sbjct: 92 TEQELPRPQSPSDLDSLDGRSLNDDGSSDPRD--IDQDNRSTSPSIYSPGSVENDSDSSS 149
Query: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS-SLIMPPLET 514
L + P PP P P P P Q +S H P M P +
Sbjct: 150 GLSQGPARPYHPP------PLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTS 203
Query: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT----ASAPLTTPH--LETPPCPAPCP 568
+ APP PP P L+ PP+ A++ + P+ + PP P
Sbjct: 204 RMFQAPPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPIS 261
Query: 569 LQ------APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
+ APP T PP TP P PPA LP PP +P
Sbjct: 262 VSSSGASGAPP----TKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317
Query: 623 PXLALPPLQAP-PSP----------PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
P L PL PSP P P P PSP H L S P+P
Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP--------HSLPPASSSAPAP 369
Query: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
P++ P+S +S + S++ S + + P Q PS P S PPP +
Sbjct: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS-------FPPPTSLSVSN 422
Query: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP------ 785
PP PS P+ S PPP LLA P PP++ S A PP
Sbjct: 423 QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST-AHPPVSTHHH 481
Query: 786 ------------PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP- 832
Q + P PP +FP P +S P A P
Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH--PLEGGSSHHAHPYAMSPSLGSL 539
Query: 833 -PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
P P PP S + P PP S S + P P PS+ P
Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST--SQGSYPCSHPSPSQGPQGA 597
Query: 892 -LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
P + ++S+ + + S P G ASPP P+ + A P +
Sbjct: 598 PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657
Query: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP--GTSGGKAAAGA 1008
+ PG+P P+ G+ G GP + P + PGP P G SG +
Sbjct: 658 K--PGSP----PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
Query: 1009 GAGASSRSPKQA 1020
A +S P A
Sbjct: 712 PAAPASGPPLSA 723
Score = 94.0 bits (232), Expect = 7e-19
Identities = 143/557 (25%), Positives = 198/557 (35%), Gaps = 58/557 (10%)
Query: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
P G + PPP TP ++ GA+GA KP +GG +P + P A
Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKP---PTTPVGGGNLPSAPPPANFPHVTPNLPP 303
Query: 89 NPASRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
PA RP AS G A P P P + G+ G PGP +KG T+A
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAP 354
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
+ P S+ A R + + S A A S ++ + P PA A P P
Sbjct: 355 SPHSLPPASSSAPAPPMRFPY--SSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 205 PRKSVSSASEH--STTEPSPAARRRPSAGGGLQRPASRSL-SSSATPLSSPARSGPSARG 261
P + S S T+PS ++ S G P R L +S+A P P +G +
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
P H + + Q + Q ++ GP P G+ P
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP--- 529
Query: 322 NAATPLPATLPPSPPLATPLPLAPP---------SPSAPPSLQTLPSPPATPPSQAPPSM 372
A +P +L P PP P L PP P+ PP + S +T P S
Sbjct: 530 YAMSPSLGSLRPYPP--GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH 587
Query: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
+P + PP+ ++T+ S ++S A SP +
Sbjct: 588 PSPSQGPQGAPYPFPPVP---TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 433 SPRQTQASLTSPSRPASTP---PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
SP + + +P S P +PP S PA P SP V P PL
Sbjct: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP--GPLPPAGP 702
Query: 490 QALSSLASHSPQAPLSSLIMPPLE-TQSSLAP------PSLQTPPASLTTPPLENLPSLA 542
L SL P AP S PPL TQ P P PPA +PP P +
Sbjct: 703 SGLPSLPP-PPAAPASG---PPLSATQIKQEPAEEYETPESPVPPARSPSPP----PKVV 754
Query: 543 PPPLQTASAPLTTPHLE 559
P + + HL+
Sbjct: 755 DVPSHASQSARFNKHLD 771
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/223 (27%), Positives = 77/223 (34%), Gaps = 20/223 (8%)
Query: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
P A +P L L P PPG PPP + + G G P + +T S
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVSSSSNSSSSTSQGSY 583
Query: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQK 132
P + P+ S G P PP + SSP + PG P G++
Sbjct: 584 PCSHPSPSQGPQGA-PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 133 GLRISAEETVARG--KATEAPKRSALSAGARRDTSGPT-PGT---PSPAMARRSRAAGTE 186
A +T K P + R TS P PGT SP +
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
Query: 187 VGLPR-PAPSARPR--PPTEGPRKSVSSASEHSTTE-PSPAAR 225
GLP P P A P PP + A E+ T E P P AR
Sbjct: 703 SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 154 bits (388), Expect = 6e-37
Identities = 229/808 (28%), Positives = 302/808 (37%), Gaps = 156/808 (19%)
Query: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
+PPP P P PP +PLP +PPS + PP L PP PPSM PP
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLP-SPPSTAPPPPPLLLEPPP-------PPSMAPPP 190
Query: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
PP L+ + P PH+L+SPS+ PP F+ +P
Sbjct: 191 ---PPVLEALSP---PHTLSSPSIPTPP-----------------------DFIPPAPPL 221
Query: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASP-PLQTSLSP--AVSPLSSPLTIHPLQALS 493
+ P PA PP PASP + T L P V+ S + ++ QA +
Sbjct: 222 AFLAPPPPPVPAPAPP----------APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEA 271
Query: 494 SLAS--HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
+ AS SP P S + P E P L T P S PP P P++T+S
Sbjct: 272 TRASPPRSPAEPKGSALGPNPE-------PHL-TFPRSFKVPP--------PTPVRTSSI 315
Query: 552 PL----TTPHLETPPC-PAPCPLQAPPS----------PLTTPPPETPSSIATPPPQAPP 596
P+ P E AP L PPS P P P+ P + P
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP---- 371
Query: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656
ASP L S TPPP APP LPP APP PP +PPL P A P P A A
Sbjct: 372 --ASPRLGQSQSQADERAGTPPP-APP---LPP-PAPPLPPPAPPLPPAAPPLPCAQKA- 423
Query: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS--------LAA------- 701
A +P S P P P SP + S+ P PS LAA
Sbjct: 424 AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 702 --PPLQVPPSPPASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
L P P +P P P+ L+ P PP P S T
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
Query: 758 PPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
P L +P P+P + L A A P + +LP P G+ +
Sbjct: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
Query: 815 PSASLPMS-PLA-TPPPQAPPVLAAPLLQ--------VPPSPPASPTL--QAPRRPPTPG 862
+ +S P+A PPQ+ +L LQ +PP P + +A P TP
Sbjct: 604 GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 921
T GP L GP +P SGP +A +++ +T +L DSGP G
Sbjct: 664 KAT--LGPATPLKATSGP-----TTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG- 715
Query: 922 AAASPPPDAELAACHPAAWSRGP--APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979
P E++ A P A L +GA + +PP T PG + C +Y+
Sbjct: 716 -QPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS-AAFPPKTSPGGGEVPC-LYKPH 772
Query: 980 GPESATPAPGALDPGPSPGTSGGKAAAGAG--------AGASSRSPKQAR-LGELPLGAL 1030
+S+ A+ P + G AAG G G ++ P A+ EL +
Sbjct: 773 CHQSSLSREVAV---VMPTLARG-GAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV 828
Query: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGG 1058
VV+ LLLAA + A G G
Sbjct: 829 TGEVVERGSPMALLLAARQRAQKGRSVG 856
Score = 124 bits (310), Expect = 7e-28
Identities = 190/758 (25%), Positives = 266/758 (35%), Gaps = 136/758 (17%)
Query: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTK 313
P P P+ P P L+ PP + PP AL P LSS + TP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF--- 214
Query: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP----------AT 363
+PP A PL PP PP+ P APP+P++P ++ T PP A
Sbjct: 215 ---IPP----APPLAFLAPPPPPVPAP---APPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
Query: 364 PPSQAPPSMTTPPMQ-APPSLQTIPPIQVPHSLTSPSLQA-PPSPLALSSLQATTSLGSP 421
QA + +PP A P + P PH S + PP+P+ SS+ + +P
Sbjct: 265 NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324
Query: 422 TLQ--ATHSFLTMSPRQTQASLTSPSR--PASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
+ AT + P + S+ P P P + + PASP L S S A
Sbjct: 325 RKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD 384
Query: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT--PPASLTTPPL 535
+P PL P AP PPL + P + + PPA T P
Sbjct: 385 ERAGTPPPAPPL---------PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK 435
Query: 536 ENLPSL-----APPPLQTASA-------PLTTPHLETPPCPAPCP-------LQAPPSPL 576
+ P+L P P TAS+ P L C L P P
Sbjct: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
Query: 577 TTPP----------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
P PE + ++ P PP G+P L + +A P L
Sbjct: 496 VAPQSKEGKKGPRLPEKETLLSLPAKDTPP--------GVPEKSLGGSSLTETEAAPSLT 547
Query: 627 LPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQA---------- 675
LP + P +P + + + +A + S PP P ++
Sbjct: 548 LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADD 607
Query: 676 -PFSPPAS---PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
S P + PP S + P + P P +PP P + P AT P PP
Sbjct: 608 DKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-AIPPKATPEPAIPPKATLWPATPPKAT 666
Query: 732 ---APPLQVPPSP------PASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMS 779
A PL+ P + P ++ +AT P L A P P PAS +S
Sbjct: 667 LGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
Query: 780 PLAKPPPQAPPALATP-PLQALPS----PPASFPG-------------QAPFSPSASLPM 821
++ + P+ AT P Q S PP + PG Q+ S ++ M
Sbjct: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVM 786
Query: 822 SPLATPPPQAP--PVLAAPLLQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALA 877
LA P PV +P PPAS PT + R P T + G + L LA
Sbjct: 787 PTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT--GEVVERGSPMALLLA 844
Query: 878 PGPPPPPSRSPSSTLSGPDLAG----HSSSATSTPEEL 911
RS + L L G HS A ++ + +
Sbjct: 845 ARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSI 882
Score = 117 bits (293), Expect = 6e-26
Identities = 147/497 (29%), Positives = 188/497 (37%), Gaps = 86/497 (17%)
Query: 475 PAVSPLSSPLTIHPLQALSS--LASHSPQAP----------LSSLIMPPLETQSSLAPPS 522
P V PL LT PL A + LA +P P SSL+ L SS+
Sbjct: 73 PRVRPL---LTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR 129
Query: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP----LQAPPSP-LT 577
L PP P AP P Q S P L +PP AP P L+ PP P +
Sbjct: 130 PGQYGQDLLIPPPP--PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
Query: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS-- 635
PPP +++ P + P++ +PP P+PPL+ LA PPP P PP A P
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP--APAPPAPASPHTV 245
Query: 636 -----PP---------------------ASPPLSPLATPSPQA--PNALAVHLLQAPFSP 667
PP ASPP SP A P A PN F
Sbjct: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP-AEPKGSALGPNPEPHLTFPRSFKV 304
Query: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
PP PV+ +S PV + P + + P ++ P PP+ S P +AP
Sbjct: 305 PPPTPVRT-----SSIPVQEAQEAPRKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAP 358
Query: 728 PPLAAPPLQVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
P P ++ + PASP + S A PP PPL P PP PP + P+ P
Sbjct: 359 EPDC--PGELKATAPASPRLGQSQSQADERAGTPPPAPPL----PPPAPPLPPPAPPLPP 412
Query: 781 LAKPPPQAPPALATPPLQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
A P P A A A PP +P PA P P SP + +P+ P L
Sbjct: 413 AAPPLPCAQKA-AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
Query: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRL----TLALAPGPPPPPSRSPSS 890
L + R PT P + GPRL TL P PP P
Sbjct: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEK 530
Query: 891 TLSGPDLAGHSSSATST 907
+L G L ++ + T
Sbjct: 531 SLGGSSLTETEAAPSLT 547
Score = 101 bits (251), Expect = 5e-21
Identities = 272/1167 (23%), Positives = 363/1167 (31%), Gaps = 239/1167 (20%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
P LL P PP P P PP + ++E GG + P +AP
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPP-----------------QDISEPPGGSPLPSPPSTAPP 172
Query: 77 AGP--------------------------TRSAGTSSRNPASRPPASGRGERAPPAKNT- 109
P T S+ + P PPA APP
Sbjct: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP 232
Query: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS--GP 167
+P P + + TR P G G+ + G+ EA + S + A S GP
Sbjct: 233 APAPPAPASPHTVGTRLFPPG--GVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
Query: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT----EGPRKSVSSASEHSTTEPSPA 223
P P R + +P P P P E PRK E T+ +P+
Sbjct: 291 NP-EPHLTFPRSFK-------VPPPTPVRTSSIPVQEAQEAPRK------EEGATKKAPS 336
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
R P RPAS+ A P +A +PR SQ +
Sbjct: 337 --RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERA------- 387
Query: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL 343
TPP AP L P + PL P+P P+PP AA PLP + P P
Sbjct: 388 -GTPP---PAPPLPP-PAPPLPPPAP------PLPP---AAPPLPCAQKAAHP---PAGF 430
Query: 344 APPSPSAPPSLQTLPSPPATP-PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
S+ P+L+ P+PP+ + + P P Q + L
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
Query: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
P P + Q+ P L + L++ + T + S S+ ++ + L+
Sbjct: 491 RPGPTV--APQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS-LT 547
Query: 463 LPASPPL-QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
LP+ + Q S +P+V + + L LSS A + + SL PP
Sbjct: 548 LPSVDYIPQDSPTPSVRQIRNELEAR----LSSAAEKEAKPSIGSL--PPKPRLEGGRIC 601
Query: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP- 580
L+ P +NL PP T P T+ + PA P +A P P P
Sbjct: 602 ENGADDDKLSKPVAKNL-----PPQSTTLLPTTSLQPKAMLGPA-IPPKATPEPAIPPKA 655
Query: 581 ---PETPSSIATPPPQAPPALASP--PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
P TP P A + P PL+ P ++ AT P L P
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715
Query: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
P P ++TPS QA PS + P S +A PP +
Sbjct: 716 QPEKPASQEVSTPS------------QARGEGSPSEATRL----PTQGARSSAAFPPKTS 759
Query: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQV--PPSPPASPPMSPSA 751
P P L P +S + P A A P P++V PP PA PP S
Sbjct: 760 PGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP 819
Query: 752 TP---------------PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
T P L A Q S A+L S L P +L
Sbjct: 820 TDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSL-------PGSLRDHS 872
Query: 797 LQALPSPPASFPGQ--------APFSPSASLPMSPLAT---------------------- 826
QA S + F Q P P + SPL T
Sbjct: 873 HQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRR 932
Query: 827 -----PPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
P PQAP +V PS P P ++ PP+P + P
Sbjct: 933 HNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP- 987
Query: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
PPP S P G SS P D A PP + A
Sbjct: 988 PPPEFSNDPEPPAPALQYLGRQSS----PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGA 1043
Query: 940 WSRGPAPPLAFRGAPGAPLP-----WPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
G F G + + P GPG G G + +P G
Sbjct: 1044 RYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG--------GTGRSLSSPNCF--G 1093
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 1054
P PG G R A G P G L A R L AA GAA
Sbjct: 1094 PQPG------------GPEMRRVNSA--GRAPPGGLHA-------PRLSLEGAARGAAEA 1132
Query: 1055 SGGGPGGAEGGGVTGGARAALSDAELG 1081
PG A+ G R+ + G
Sbjct: 1133 KHKAPGSADYGFAPAAGRSPYTTTRYG 1159
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/445 (28%), Positives = 167/445 (37%), Gaps = 68/445 (15%)
Query: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
P+ P L PL + LA P P P A + S + L ++
Sbjct: 73 PRVRPLLTFLPLNAQEN---HGLAVPTPSVPDDFADKEVTGTSSL-VNGNLRLYSSVGDL 128
Query: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
P LL P PPP P P P SP +PPS APP PPL + P PP
Sbjct: 129 RPGQYGQDLLIPP--PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP---PPLLLEPPPP 183
Query: 712 AS-----PPMSPSATPPPQ-APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
S PP+ + +PP + P + PP +PP +PP++ A PPP VP APP
Sbjct: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP----APPLAFLAPPPPPVP--APAPP 237
Query: 766 LQVPPS-------PPASLP--MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
P PP + S +A QA A+PP ++ P S G P P
Sbjct: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP-RSPAEPKGSALGPNP-EPH 295
Query: 817 ASLPMSPLATPPPQAPPVLAAPL--LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
+ P S PPP + P+ Q P T +AP R P P +
Sbjct: 296 LTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP----------SF 344
Query: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934
+ P P R+P PD G AT+ G A +PPP L
Sbjct: 345 HIRPASQVYPDRAPE-----PDCPG-ELKATAPASPRLGQSQSQADERAGTPPPAPPLPP 398
Query: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
PA PAPPL AP P A P T+ P+S++P AL P
Sbjct: 399 --PAPPLPPPAPPLP-PAAPPLPCAQKAAHPPAGF--------TKTPKSSSP---ALKPK 444
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQ 1019
P+P + A++ A R P Q
Sbjct: 445 PNPPSPENTASS---APVDWRDPSQ 466
Score = 82.0 bits (201), Expect = 3e-15
Identities = 171/709 (24%), Positives = 232/709 (32%), Gaps = 103/709 (14%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
+ + +A A PA P P PP +P PP P P A+
Sbjct: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL--------------PCAQ 421
Query: 61 RAG--GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAPPAKNTSPGPVSSP 117
+A G P+S+ A + S N AS P R + +N +
Sbjct: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
Query: 118 GRASG--TTRPGPL-------GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
R + RPGP G+KG R+ +ET+ A + P
Sbjct: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP----------------- 524
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-- 226
PG P ++ S TE PS P + P SV S AA +
Sbjct: 525 PGVPEKSLG-GSSLTETEAAPSLTLPSV-DYIPQDSPTPSVRQIRNELEARLSSAAEKEA 582
Query: 227 RPSAGGGLQRP---ASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
+PS G +P R + A LS P + T P QPK A+
Sbjct: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK-----AML 637
Query: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGT--KARPVPPPDNAATPLPATLPPS-PPLA 338
P + PP+ PA+ P ++ ATP P T A P+ TPL AT P+ A
Sbjct: 638 GPAI-PPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
Query: 339 TPLPL-----------APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
T LP P P+ Q + +P +P T P Q S P
Sbjct: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
Query: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
P P P L P SSL ++ PTL + P + P P
Sbjct: 756 PKTSPGGGEVPCLYKP--HCHQSSLSREVAVVMPTLARGGA---AGPGEPVEVKEPPGLP 810
Query: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL----------SSLAS 497
A P + P L P + + SP L++ +++ SL
Sbjct: 811 AKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRD 870
Query: 498 HSPQAPLSS-LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--QTASAPLT 554
HS QA SS I T +S A +P +P+ P L L+
Sbjct: 871 HSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELS 930
Query: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
H T P P QAP + P P P + P S + +
Sbjct: 931 RRHNWTKPEP-----QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEV 985
Query: 615 ATPPPQ-----APPXLALPPLQAPPSPPAS--PPLSPLATPSPQAPNAL 656
PPP+ PP AL L SPP + L L P AP AL
Sbjct: 986 IPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPAL 1034
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 154 bits (388), Expect = 6e-37
Identities = 229/808 (28%), Positives = 302/808 (37%), Gaps = 156/808 (19%)
Query: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
+PPP P P PP +PLP +PPS + PP L PP PPSM PP
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLP-SPPSTAPPPPPLLLEPPP-------PPSMAPPP 190
Query: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
PP L+ + P PH+L+SPS+ PP F+ +P
Sbjct: 191 ---PPVLEALSP---PHTLSSPSIPTPP-----------------------DFIPPAPPL 221
Query: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASP-PLQTSLSP--AVSPLSSPLTIHPLQALS 493
+ P PA PP PASP + T L P V+ S + ++ QA +
Sbjct: 222 AFLAPPPPPVPAPAPP----------APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEA 271
Query: 494 SLAS--HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
+ AS SP P S + P E P L T P S PP P P++T+S
Sbjct: 272 TRASPPRSPAEPKGSALGPNPE-------PHL-TFPRSFKVPP--------PTPVRTSSI 315
Query: 552 PL----TTPHLETPPC-PAPCPLQAPPS----------PLTTPPPETPSSIATPPPQAPP 596
P+ P E AP L PPS P P P+ P + P
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP---- 371
Query: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656
ASP L S TPPP APP LPP APP PP +PPL P A P P A A
Sbjct: 372 --ASPRLGQSQSQADERAGTPPP-APP---LPP-PAPPLPPPAPPLPPAAPPLPCAQKA- 423
Query: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS--------LAA------- 701
A +P S P P P SP + S+ P PS LAA
Sbjct: 424 AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 702 --PPLQVPPSPPASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
L P P +P P P+ L+ P PP P S T
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
Query: 758 PPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
P L +P P+P + L A A P + +LP P G+ +
Sbjct: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
Query: 815 PSASLPMS-PLA-TPPPQAPPVLAAPLLQ--------VPPSPPASPTL--QAPRRPPTPG 862
+ +S P+A PPQ+ +L LQ +PP P + +A P TP
Sbjct: 604 GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 921
T GP L GP +P SGP +A +++ +T +L DSGP G
Sbjct: 664 KAT--LGPATPLKATSGP-----TTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG- 715
Query: 922 AAASPPPDAELAACHPAAWSRGP--APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979
P E++ A P A L +GA + +PP T PG + C +Y+
Sbjct: 716 -QPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS-AAFPPKTSPGGGEVPC-LYKPH 772
Query: 980 GPESATPAPGALDPGPSPGTSGGKAAAGAG--------AGASSRSPKQAR-LGELPLGAL 1030
+S+ A+ P + G AAG G G ++ P A+ EL +
Sbjct: 773 CHQSSLSREVAV---VMPTLARG-GAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV 828
Query: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGG 1058
VV+ LLLAA + A G G
Sbjct: 829 TGEVVERGSPMALLLAARQRAQKGRSVG 856
Score = 124 bits (310), Expect = 7e-28
Identities = 190/758 (25%), Positives = 266/758 (35%), Gaps = 136/758 (17%)
Query: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTK 313
P P P+ P P L+ PP + PP AL P LSS + TP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF--- 214
Query: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP----------AT 363
+PP A PL PP PP+ P APP+P++P ++ T PP A
Sbjct: 215 ---IPP----APPLAFLAPPPPPVPAP---APPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
Query: 364 PPSQAPPSMTTPPMQ-APPSLQTIPPIQVPHSLTSPSLQA-PPSPLALSSLQATTSLGSP 421
QA + +PP A P + P PH S + PP+P+ SS+ + +P
Sbjct: 265 NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324
Query: 422 TLQ--ATHSFLTMSPRQTQASLTSPSR--PASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
+ AT + P + S+ P P P + + PASP L S S A
Sbjct: 325 RKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD 384
Query: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT--PPASLTTPPL 535
+P PL P AP PPL + P + + PPA T P
Sbjct: 385 ERAGTPPPAPPL---------PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK 435
Query: 536 ENLPSL-----APPPLQTASA-------PLTTPHLETPPCPAPCP-------LQAPPSPL 576
+ P+L P P TAS+ P L C L P P
Sbjct: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
Query: 577 TTPP----------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
P PE + ++ P PP G+P L + +A P L
Sbjct: 496 VAPQSKEGKKGPRLPEKETLLSLPAKDTPP--------GVPEKSLGGSSLTETEAAPSLT 547
Query: 627 LPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQA---------- 675
LP + P +P + + + +A + S PP P ++
Sbjct: 548 LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADD 607
Query: 676 -PFSPPAS---PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
S P + PP S + P + P P +PP P + P AT P PP
Sbjct: 608 DKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-AIPPKATPEPAIPPKATLWPATPPKAT 666
Query: 732 ---APPLQVPPSP------PASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMS 779
A PL+ P + P ++ +AT P L A P P PAS +S
Sbjct: 667 LGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
Query: 780 PLAKPPPQAPPALATP-PLQALPS----PPASFPG-------------QAPFSPSASLPM 821
++ + P+ AT P Q S PP + PG Q+ S ++ M
Sbjct: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVM 786
Query: 822 SPLATPPPQAP--PVLAAPLLQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALA 877
LA P PV +P PPAS PT + R P T + G + L LA
Sbjct: 787 PTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT--GEVVERGSPMALLLA 844
Query: 878 PGPPPPPSRSPSSTLSGPDLAG----HSSSATSTPEEL 911
RS + L L G HS A ++ + +
Sbjct: 845 ARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSI 882
Score = 117 bits (293), Expect = 6e-26
Identities = 147/497 (29%), Positives = 188/497 (37%), Gaps = 86/497 (17%)
Query: 475 PAVSPLSSPLTIHPLQALSS--LASHSPQAP----------LSSLIMPPLETQSSLAPPS 522
P V PL LT PL A + LA +P P SSL+ L SS+
Sbjct: 73 PRVRPL---LTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR 129
Query: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP----LQAPPSP-LT 577
L PP P AP P Q S P L +PP AP P L+ PP P +
Sbjct: 130 PGQYGQDLLIPPPP--PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
Query: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS-- 635
PPP +++ P + P++ +PP P+PPL+ LA PPP P PP A P
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP--APAPPAPASPHTV 245
Query: 636 -----PP---------------------ASPPLSPLATPSPQA--PNALAVHLLQAPFSP 667
PP ASPP SP A P A PN F
Sbjct: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP-AEPKGSALGPNPEPHLTFPRSFKV 304
Query: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
PP PV+ +S PV + P + + P ++ P PP+ S P +AP
Sbjct: 305 PPPTPVRT-----SSIPVQEAQEAPRKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAP 358
Query: 728 PPLAAPPLQVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
P P ++ + PASP + S A PP PPL P PP PP + P+ P
Sbjct: 359 EPDC--PGELKATAPASPRLGQSQSQADERAGTPPPAPPL----PPPAPPLPPPAPPLPP 412
Query: 781 LAKPPPQAPPALATPPLQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
A P P A A A PP +P PA P P SP + +P+ P L
Sbjct: 413 AAPPLPCAQKA-AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
Query: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRL----TLALAPGPPPPPSRSPSS 890
L + R PT P + GPRL TL P PP P
Sbjct: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEK 530
Query: 891 TLSGPDLAGHSSSATST 907
+L G L ++ + T
Sbjct: 531 SLGGSSLTETEAAPSLT 547
Score = 101 bits (251), Expect = 5e-21
Identities = 272/1167 (23%), Positives = 363/1167 (31%), Gaps = 239/1167 (20%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
P LL P PP P P PP + ++E GG + P +AP
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPP-----------------QDISEPPGGSPLPSPPSTAPP 172
Query: 77 AGP--------------------------TRSAGTSSRNPASRPPASGRGERAPPAKNT- 109
P T S+ + P PPA APP
Sbjct: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP 232
Query: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS--GP 167
+P P + + TR P G G+ + G+ EA + S + A S GP
Sbjct: 233 APAPPAPASPHTVGTRLFPPG--GVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
Query: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT----EGPRKSVSSASEHSTTEPSPA 223
P P R + +P P P P E PRK E T+ +P+
Sbjct: 291 NP-EPHLTFPRSFK-------VPPPTPVRTSSIPVQEAQEAPRK------EEGATKKAPS 336
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
R P RPAS+ A P +A +PR SQ +
Sbjct: 337 --RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERA------- 387
Query: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL 343
TPP AP L P + PL P+P P+PP AA PLP + P P
Sbjct: 388 -GTPP---PAPPLPP-PAPPLPPPAP------PLPP---AAPPLPCAQKAAHP---PAGF 430
Query: 344 APPSPSAPPSLQTLPSPPATP-PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
S+ P+L+ P+PP+ + + P P Q + L
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
Query: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
P P + Q+ P L + L++ + T + S S+ ++ + L+
Sbjct: 491 RPGPTV--APQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS-LT 547
Query: 463 LPASPPL-QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
LP+ + Q S +P+V + + L LSS A + + SL PP
Sbjct: 548 LPSVDYIPQDSPTPSVRQIRNELEAR----LSSAAEKEAKPSIGSL--PPKPRLEGGRIC 601
Query: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP- 580
L+ P +NL PP T P T+ + PA P +A P P P
Sbjct: 602 ENGADDDKLSKPVAKNL-----PPQSTTLLPTTSLQPKAMLGPA-IPPKATPEPAIPPKA 655
Query: 581 ---PETPSSIATPPPQAPPALASP--PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
P TP P A + P PL+ P ++ AT P L P
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715
Query: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
P P ++TPS QA PS + P S +A PP +
Sbjct: 716 QPEKPASQEVSTPS------------QARGEGSPSEATRL----PTQGARSSAAFPPKTS 759
Query: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQV--PPSPPASPPMSPSA 751
P P L P +S + P A A P P++V PP PA PP S
Sbjct: 760 PGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP 819
Query: 752 TP---------------PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
T P L A Q S A+L S L P +L
Sbjct: 820 TDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSL-------PGSLRDHS 872
Query: 797 LQALPSPPASFPGQ--------APFSPSASLPMSPLAT---------------------- 826
QA S + F Q P P + SPL T
Sbjct: 873 HQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRR 932
Query: 827 -----PPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
P PQAP +V PS P P ++ PP+P + P
Sbjct: 933 HNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP- 987
Query: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
PPP S P G SS P D A PP + A
Sbjct: 988 PPPEFSNDPEPPAPALQYLGRQSS----PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGA 1043
Query: 940 WSRGPAPPLAFRGAPGAPLP-----WPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
G F G + + P GPG G G + +P G
Sbjct: 1044 RYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG--------GTGRSLSSPNCF--G 1093
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 1054
P PG G R A G P G L A R L AA GAA
Sbjct: 1094 PQPG------------GPEMRRVNSA--GRAPPGGLHA-------PRLSLEGAARGAAEA 1132
Query: 1055 SGGGPGGAEGGGVTGGARAALSDAELG 1081
PG A+ G R+ + G
Sbjct: 1133 KHKAPGSADYGFAPAAGRSPYTTTRYG 1159
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/445 (28%), Positives = 167/445 (37%), Gaps = 68/445 (15%)
Query: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
P+ P L PL + LA P P P A + S + L ++
Sbjct: 73 PRVRPLLTFLPLNAQEN---HGLAVPTPSVPDDFADKEVTGTSSL-VNGNLRLYSSVGDL 128
Query: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
P LL P PPP P P P SP +PPS APP PPL + P PP
Sbjct: 129 RPGQYGQDLLIPP--PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP---PPLLLEPPPP 183
Query: 712 AS-----PPMSPSATPPPQ-APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
S PP+ + +PP + P + PP +PP +PP++ A PPP VP APP
Sbjct: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP----APPLAFLAPPPPPVP--APAPP 237
Query: 766 LQVPPS-------PPASLP--MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
P PP + S +A QA A+PP ++ P S G P P
Sbjct: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP-RSPAEPKGSALGPNP-EPH 295
Query: 817 ASLPMSPLATPPPQAPPVLAAPL--LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
+ P S PPP + P+ Q P T +AP R P P +
Sbjct: 296 LTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP----------SF 344
Query: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934
+ P P R+P PD G AT+ G A +PPP L
Sbjct: 345 HIRPASQVYPDRAPE-----PDCPG-ELKATAPASPRLGQSQSQADERAGTPPPAPPLPP 398
Query: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
PA PAPPL AP P A P T+ P+S++P AL P
Sbjct: 399 --PAPPLPPPAPPLP-PAAPPLPCAQKAAHPPAGF--------TKTPKSSSP---ALKPK 444
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQ 1019
P+P + A++ A R P Q
Sbjct: 445 PNPPSPENTASS---APVDWRDPSQ 466
Score = 82.0 bits (201), Expect = 3e-15
Identities = 171/709 (24%), Positives = 232/709 (32%), Gaps = 103/709 (14%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
+ + +A A PA P P PP +P PP P P A+
Sbjct: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL--------------PCAQ 421
Query: 61 RAG--GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAPPAKNTSPGPVSSP 117
+A G P+S+ A + S N AS P R + +N +
Sbjct: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
Query: 118 GRASG--TTRPGPL-------GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
R + RPGP G+KG R+ +ET+ A + P
Sbjct: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP----------------- 524
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-- 226
PG P ++ S TE PS P + P SV S AA +
Sbjct: 525 PGVPEKSLG-GSSLTETEAAPSLTLPSV-DYIPQDSPTPSVRQIRNELEARLSSAAEKEA 582
Query: 227 RPSAGGGLQRP---ASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
+PS G +P R + A LS P + T P QPK A+
Sbjct: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK-----AML 637
Query: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGT--KARPVPPPDNAATPLPATLPPS-PPLA 338
P + PP+ PA+ P ++ ATP P T A P+ TPL AT P+ A
Sbjct: 638 GPAI-PPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
Query: 339 TPLPL-----------APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
T LP P P+ Q + +P +P T P Q S P
Sbjct: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
Query: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
P P P L P SSL ++ PTL + P + P P
Sbjct: 756 PKTSPGGGEVPCLYKP--HCHQSSLSREVAVVMPTLARGGA---AGPGEPVEVKEPPGLP 810
Query: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL----------SSLAS 497
A P + P L P + + SP L++ +++ SL
Sbjct: 811 AKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRD 870
Query: 498 HSPQAPLSS-LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--QTASAPLT 554
HS QA SS I T +S A +P +P+ P L L+
Sbjct: 871 HSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELS 930
Query: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
H T P P QAP + P P P + P S + +
Sbjct: 931 RRHNWTKPEP-----QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEV 985
Query: 615 ATPPPQ-----APPXLALPPLQAPPSPPAS--PPLSPLATPSPQAPNAL 656
PPP+ PP AL L SPP + L L P AP AL
Sbjct: 986 IPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPAL 1034
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 154 bits (388), Expect = 6e-37
Identities = 229/808 (28%), Positives = 302/808 (37%), Gaps = 156/808 (19%)
Query: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
+PPP P P PP +PLP +PPS + PP L PP PPSM PP
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLP-SPPSTAPPPPPLLLEPPP-------PPSMAPPP 190
Query: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
PP L+ + P PH+L+SPS+ PP F+ +P
Sbjct: 191 ---PPVLEALSP---PHTLSSPSIPTPP-----------------------DFIPPAPPL 221
Query: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASP-PLQTSLSP--AVSPLSSPLTIHPLQALS 493
+ P PA PP PASP + T L P V+ S + ++ QA +
Sbjct: 222 AFLAPPPPPVPAPAPP----------APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEA 271
Query: 494 SLAS--HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
+ AS SP P S + P E P L T P S PP P P++T+S
Sbjct: 272 TRASPPRSPAEPKGSALGPNPE-------PHL-TFPRSFKVPP--------PTPVRTSSI 315
Query: 552 PL----TTPHLETPPC-PAPCPLQAPPS----------PLTTPPPETPSSIATPPPQAPP 596
P+ P E AP L PPS P P P+ P + P
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP---- 371
Query: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656
ASP L S TPPP APP LPP APP PP +PPL P A P P A A
Sbjct: 372 --ASPRLGQSQSQADERAGTPPP-APP---LPP-PAPPLPPPAPPLPPAAPPLPCAQKA- 423
Query: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS--------LAA------- 701
A +P S P P P SP + S+ P PS LAA
Sbjct: 424 AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 702 --PPLQVPPSPPASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
L P P +P P P+ L+ P PP P S T
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
Query: 758 PPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
P L +P P+P + L A A P + +LP P G+ +
Sbjct: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
Query: 815 PSASLPMS-PLA-TPPPQAPPVLAAPLLQ--------VPPSPPASPTL--QAPRRPPTPG 862
+ +S P+A PPQ+ +L LQ +PP P + +A P TP
Sbjct: 604 GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 921
T GP L GP +P SGP +A +++ +T +L DSGP G
Sbjct: 664 KAT--LGPATPLKATSGP-----TTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG- 715
Query: 922 AAASPPPDAELAACHPAAWSRGP--APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979
P E++ A P A L +GA + +PP T PG + C +Y+
Sbjct: 716 -QPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS-AAFPPKTSPGGGEVPC-LYKPH 772
Query: 980 GPESATPAPGALDPGPSPGTSGGKAAAGAG--------AGASSRSPKQAR-LGELPLGAL 1030
+S+ A+ P + G AAG G G ++ P A+ EL +
Sbjct: 773 CHQSSLSREVAV---VMPTLARG-GAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV 828
Query: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGG 1058
VV+ LLLAA + A G G
Sbjct: 829 TGEVVERGSPMALLLAARQRAQKGRSVG 856
Score = 124 bits (310), Expect = 7e-28
Identities = 190/758 (25%), Positives = 266/758 (35%), Gaps = 136/758 (17%)
Query: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTK 313
P P P+ P P L+ PP + PP AL P LSS + TP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF--- 214
Query: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP----------AT 363
+PP A PL PP PP+ P APP+P++P ++ T PP A
Sbjct: 215 ---IPP----APPLAFLAPPPPPVPAP---APPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
Query: 364 PPSQAPPSMTTPPMQ-APPSLQTIPPIQVPHSLTSPSLQA-PPSPLALSSLQATTSLGSP 421
QA + +PP A P + P PH S + PP+P+ SS+ + +P
Sbjct: 265 NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324
Query: 422 TLQ--ATHSFLTMSPRQTQASLTSPSR--PASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
+ AT + P + S+ P P P + + PASP L S S A
Sbjct: 325 RKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD 384
Query: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT--PPASLTTPPL 535
+P PL P AP PPL + P + + PPA T P
Sbjct: 385 ERAGTPPPAPPL---------PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK 435
Query: 536 ENLPSL-----APPPLQTASA-------PLTTPHLETPPCPAPCP-------LQAPPSPL 576
+ P+L P P TAS+ P L C L P P
Sbjct: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
Query: 577 TTPP----------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
P PE + ++ P PP G+P L + +A P L
Sbjct: 496 VAPQSKEGKKGPRLPEKETLLSLPAKDTPP--------GVPEKSLGGSSLTETEAAPSLT 547
Query: 627 LPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQA---------- 675
LP + P +P + + + +A + S PP P ++
Sbjct: 548 LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADD 607
Query: 676 -PFSPPAS---PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
S P + PP S + P + P P +PP P + P AT P PP
Sbjct: 608 DKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-AIPPKATPEPAIPPKATLWPATPPKAT 666
Query: 732 ---APPLQVPPSP------PASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMS 779
A PL+ P + P ++ +AT P L A P P PAS +S
Sbjct: 667 LGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
Query: 780 PLAKPPPQAPPALATP-PLQALPS----PPASFPG-------------QAPFSPSASLPM 821
++ + P+ AT P Q S PP + PG Q+ S ++ M
Sbjct: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVM 786
Query: 822 SPLATPPPQAP--PVLAAPLLQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALA 877
LA P PV +P PPAS PT + R P T + G + L LA
Sbjct: 787 PTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT--GEVVERGSPMALLLA 844
Query: 878 PGPPPPPSRSPSSTLSGPDLAG----HSSSATSTPEEL 911
RS + L L G HS A ++ + +
Sbjct: 845 ARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSI 882
Score = 117 bits (293), Expect = 6e-26
Identities = 147/497 (29%), Positives = 188/497 (37%), Gaps = 86/497 (17%)
Query: 475 PAVSPLSSPLTIHPLQALSS--LASHSPQAP----------LSSLIMPPLETQSSLAPPS 522
P V PL LT PL A + LA +P P SSL+ L SS+
Sbjct: 73 PRVRPL---LTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR 129
Query: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP----LQAPPSP-LT 577
L PP P AP P Q S P L +PP AP P L+ PP P +
Sbjct: 130 PGQYGQDLLIPPPP--PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
Query: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS-- 635
PPP +++ P + P++ +PP P+PPL+ LA PPP P PP A P
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP--APAPPAPASPHTV 245
Query: 636 -----PP---------------------ASPPLSPLATPSPQA--PNALAVHLLQAPFSP 667
PP ASPP SP A P A PN F
Sbjct: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP-AEPKGSALGPNPEPHLTFPRSFKV 304
Query: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
PP PV+ +S PV + P + + P ++ P PP+ S P +AP
Sbjct: 305 PPPTPVRT-----SSIPVQEAQEAPRKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAP 358
Query: 728 PPLAAPPLQVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
P P ++ + PASP + S A PP PPL P PP PP + P+ P
Sbjct: 359 EPDC--PGELKATAPASPRLGQSQSQADERAGTPPPAPPL----PPPAPPLPPPAPPLPP 412
Query: 781 LAKPPPQAPPALATPPLQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
A P P A A A PP +P PA P P SP + +P+ P L
Sbjct: 413 AAPPLPCAQKA-AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
Query: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRL----TLALAPGPPPPPSRSPSS 890
L + R PT P + GPRL TL P PP P
Sbjct: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEK 530
Query: 891 TLSGPDLAGHSSSATST 907
+L G L ++ + T
Sbjct: 531 SLGGSSLTETEAAPSLT 547
Score = 101 bits (251), Expect = 5e-21
Identities = 272/1167 (23%), Positives = 363/1167 (31%), Gaps = 239/1167 (20%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
P LL P PP P P PP + ++E GG + P +AP
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPP-----------------QDISEPPGGSPLPSPPSTAPP 172
Query: 77 AGP--------------------------TRSAGTSSRNPASRPPASGRGERAPPAKNT- 109
P T S+ + P PPA APP
Sbjct: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP 232
Query: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS--GP 167
+P P + + TR P G G+ + G+ EA + S + A S GP
Sbjct: 233 APAPPAPASPHTVGTRLFPPG--GVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
Query: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT----EGPRKSVSSASEHSTTEPSPA 223
P P R + +P P P P E PRK E T+ +P+
Sbjct: 291 NP-EPHLTFPRSFK-------VPPPTPVRTSSIPVQEAQEAPRK------EEGATKKAPS 336
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
R P RPAS+ A P +A +PR SQ +
Sbjct: 337 --RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERA------- 387
Query: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL 343
TPP AP L P + PL P+P P+PP AA PLP + P P
Sbjct: 388 -GTPP---PAPPLPP-PAPPLPPPAP------PLPP---AAPPLPCAQKAAHP---PAGF 430
Query: 344 APPSPSAPPSLQTLPSPPATP-PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
S+ P+L+ P+PP+ + + P P Q + L
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
Query: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
P P + Q+ P L + L++ + T + S S+ ++ + L+
Sbjct: 491 RPGPTV--APQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS-LT 547
Query: 463 LPASPPL-QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
LP+ + Q S +P+V + + L LSS A + + SL PP
Sbjct: 548 LPSVDYIPQDSPTPSVRQIRNELEAR----LSSAAEKEAKPSIGSL--PPKPRLEGGRIC 601
Query: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP- 580
L+ P +NL PP T P T+ + PA P +A P P P
Sbjct: 602 ENGADDDKLSKPVAKNL-----PPQSTTLLPTTSLQPKAMLGPA-IPPKATPEPAIPPKA 655
Query: 581 ---PETPSSIATPPPQAPPALASP--PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
P TP P A + P PL+ P ++ AT P L P
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715
Query: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
P P ++TPS QA PS + P S +A PP +
Sbjct: 716 QPEKPASQEVSTPS------------QARGEGSPSEATRL----PTQGARSSAAFPPKTS 759
Query: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQV--PPSPPASPPMSPSA 751
P P L P +S + P A A P P++V PP PA PP S
Sbjct: 760 PGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP 819
Query: 752 TP---------------PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
T P L A Q S A+L S L P +L
Sbjct: 820 TDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSL-------PGSLRDHS 872
Query: 797 LQALPSPPASFPGQ--------APFSPSASLPMSPLAT---------------------- 826
QA S + F Q P P + SPL T
Sbjct: 873 HQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRR 932
Query: 827 -----PPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
P PQAP +V PS P P ++ PP+P + P
Sbjct: 933 HNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP- 987
Query: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
PPP S P G SS P D A PP + A
Sbjct: 988 PPPEFSNDPEPPAPALQYLGRQSS----PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGA 1043
Query: 940 WSRGPAPPLAFRGAPGAPLP-----WPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
G F G + + P GPG G G + +P G
Sbjct: 1044 RYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG--------GTGRSLSSPNCF--G 1093
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 1054
P PG G R A G P G L A R L AA GAA
Sbjct: 1094 PQPG------------GPEMRRVNSA--GRAPPGGLHA-------PRLSLEGAARGAAEA 1132
Query: 1055 SGGGPGGAEGGGVTGGARAALSDAELG 1081
PG A+ G R+ + G
Sbjct: 1133 KHKAPGSADYGFAPAAGRSPYTTTRYG 1159
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/445 (28%), Positives = 167/445 (37%), Gaps = 68/445 (15%)
Query: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
P+ P L PL + LA P P P A + S + L ++
Sbjct: 73 PRVRPLLTFLPLNAQEN---HGLAVPTPSVPDDFADKEVTGTSSL-VNGNLRLYSSVGDL 128
Query: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
P LL P PPP P P P SP +PPS APP PPL + P PP
Sbjct: 129 RPGQYGQDLLIPP--PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP---PPLLLEPPPP 183
Query: 712 AS-----PPMSPSATPPPQ-APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
S PP+ + +PP + P + PP +PP +PP++ A PPP VP APP
Sbjct: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP----APPLAFLAPPPPPVP--APAPP 237
Query: 766 LQVPPS-------PPASLP--MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
P PP + S +A QA A+PP ++ P S G P P
Sbjct: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP-RSPAEPKGSALGPNP-EPH 295
Query: 817 ASLPMSPLATPPPQAPPVLAAPL--LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
+ P S PPP + P+ Q P T +AP R P P +
Sbjct: 296 LTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP----------SF 344
Query: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934
+ P P R+P PD G AT+ G A +PPP L
Sbjct: 345 HIRPASQVYPDRAPE-----PDCPG-ELKATAPASPRLGQSQSQADERAGTPPPAPPLPP 398
Query: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
PA PAPPL AP P A P T+ P+S++P AL P
Sbjct: 399 --PAPPLPPPAPPLP-PAAPPLPCAQKAAHPPAGF--------TKTPKSSSP---ALKPK 444
Query: 995 PSPGTSGGKAAAGAGAGASSRSPKQ 1019
P+P + A++ A R P Q
Sbjct: 445 PNPPSPENTASS---APVDWRDPSQ 466
Score = 82.0 bits (201), Expect = 3e-15
Identities = 171/709 (24%), Positives = 232/709 (32%), Gaps = 103/709 (14%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
+ + +A A PA P P PP +P PP P P A+
Sbjct: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL--------------PCAQ 421
Query: 61 RAG--GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAPPAKNTSPGPVSSP 117
+A G P+S+ A + S N AS P R + +N +
Sbjct: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
Query: 118 GRASG--TTRPGPL-------GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
R + RPGP G+KG R+ +ET+ A + P
Sbjct: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP----------------- 524
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-- 226
PG P ++ S TE PS P + P SV S AA +
Sbjct: 525 PGVPEKSLG-GSSLTETEAAPSLTLPSV-DYIPQDSPTPSVRQIRNELEARLSSAAEKEA 582
Query: 227 RPSAGGGLQRP---ASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
+PS G +P R + A LS P + T P QPK A+
Sbjct: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK-----AML 637
Query: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGT--KARPVPPPDNAATPLPATLPPS-PPLA 338
P + PP+ PA+ P ++ ATP P T A P+ TPL AT P+ A
Sbjct: 638 GPAI-PPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
Query: 339 TPLPL-----------APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
T LP P P+ Q + +P +P T P Q S P
Sbjct: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
Query: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
P P P L P SSL ++ PTL + P + P P
Sbjct: 756 PKTSPGGGEVPCLYKP--HCHQSSLSREVAVVMPTLARGGA---AGPGEPVEVKEPPGLP 810
Query: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL----------SSLAS 497
A P + P L P + + SP L++ +++ SL
Sbjct: 811 AKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRD 870
Query: 498 HSPQAPLSS-LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--QTASAPLT 554
HS QA SS I T +S A +P +P+ P L L+
Sbjct: 871 HSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELS 930
Query: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
H T P P QAP + P P P + P S + +
Sbjct: 931 RRHNWTKPEP-----QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEV 985
Query: 615 ATPPPQ-----APPXLALPPLQAPPSPPAS--PPLSPLATPSPQAPNAL 656
PPP+ PP AL L SPP + L L P AP AL
Sbjct: 986 IPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPAL 1034
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 154 bits (388), Expect = 6e-37
Identities = 145/442 (32%), Positives = 181/442 (40%), Gaps = 60/442 (13%)
Query: 513 ETQSSLAPPSLQTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLET-PPCPAPCPLQ 570
++ SS LQ P +L P + PS APP P TP PP +P Q
Sbjct: 170 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ 229
Query: 571 APPSPLTTPPPETPSSIATPP---PQAPPALASPPLQGLPSPPLSPLATPPPQ-APPXLA 626
AP P P + I P PQ PP+ PP P PPL PL Q + P A
Sbjct: 230 APNQPQAPTAPVPHTHIQQAPALHPQRPPS-PHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288
Query: 627 LPPL--QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPAS 682
PPL Q PP P + L P P P L PP + QAP SP A+
Sbjct: 289 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL----------PPQASQGQAPLGTSPAAA 338
Query: 683 PPVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPP-PQAPPPLAA--PPLQV 737
P + P SQ+ PP + +PP+P A P + P T P PQ P P A PP
Sbjct: 339 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 398
Query: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP- 796
PSP + M+ + PPP + PL + P + P L + P ++P P +P A PP
Sbjct: 399 GPSPFS---MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---AQPPG 452
Query: 797 ---LQALPSPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPT 851
Q LP PPAS P P P P A P P PP + P +PPA P
Sbjct: 453 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 509
Query: 852 LQAPRRPPTPG----------------PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
A +PP G P + L A P PPPP RSPS +
Sbjct: 510 TSA--QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 567
Query: 896 DLAGHSSSATSTPEEL-RGYDS 916
D H+S + + L RGY+S
Sbjct: 568 DTPSHASQSARFYKHLDRGYNS 589
Score = 134 bits (338), Expect = 4e-31
Identities = 174/637 (27%), Positives = 226/637 (35%), Gaps = 93/637 (14%)
Query: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
RRSR + + + R A P T + + S+ +S + S ++ S +++
Sbjct: 21 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN--DSKAETVKKS 78
Query: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
A + +++PL S R S K K + RP +P+ G
Sbjct: 79 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPN---------SPSEG 129
Query: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
SS + + G+ DN +T SP + +P S S+
Sbjct: 130 EGESSDSRSVNDEGSSDPKDIDQDNRST--------SPSIPSPQDNESDSDSSAQQQMLQ 181
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATT 416
PPA QAP +T P APP +P L P P+P S A
Sbjct: 182 AQPPAL---QAPTGVTPAPSSAPPG--------------TPQLPTPGPTP----SATAVP 220
Query: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
GSPT + +P Q QA P + P + QAP P PP SP
Sbjct: 221 PQGSPTA-------SQAPNQPQA-------PTAPVPHTHIQQAPALHPQRPP-----SPH 261
Query: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
P SP PLQ L+ A P AP S PPL Q P SLQ P L P
Sbjct: 262 PPPHPSPHP--PLQPLTGSAGQ-PSAP--SHAQPPLHGQGPPGPHSLQAGP--LLQHPGP 314
Query: 537 NLPSLAPPPLQTASAPL-TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
P PP APL T+P P P PP E P P P A
Sbjct: 315 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP---LPPAPLAM 371
Query: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655
P + PP +P P PP P PPA PLS L+T P P+A
Sbjct: 372 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP--PSA 429
Query: 656 LAVHLLQAPFSPP-PSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPP----- 708
L P S P PS P Q P + + P P++ PP+ PP P
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489
Query: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
PP +PP PS + PP P A PP + S S P A +
Sbjct: 490 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 549
Query: 769 PPSPPASLPMSPLAKPPPQAP---PALATPPLQALPS 802
P SPP PPP++P P + P A S
Sbjct: 550 PESPP----------PPPRSPSPEPTVVDTPSHASQS 576
Score = 121 bits (303), Expect = 4e-27
Identities = 132/435 (30%), Positives = 158/435 (36%), Gaps = 61/435 (14%)
Query: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
ST P P Q S S Q L L +P + P A SS +PQ P
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTP--APSSAPPGTPQLPT---- 209
Query: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
P T S+ A P +P AS P P+ P AP P P P P P
Sbjct: 210 --PGPTPSATAVPPQGSPTAS-QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 266
Query: 569 LQAPP-SPLT--TPPPETPSSIATPP-----PQAPPALASPPLQGLPSPPLSPLATPPP- 619
PP PLT P PS A PP P P +L + PL P PP P PP
Sbjct: 267 SPHPPLQPLTGSAGQPSAPSH-AQPPLHGQGPPGPHSLQAGPLLQHPGPP-QPFGLPPQA 324
Query: 620 -QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Q L P A P P S A S Q P + PP+P
Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL---------PPAPLAMPHIK 375
Query: 679 PPASPPVSPSATPPSQA-PPSLAAP-PLQVP---PSPPASPPMSPSAT--PPPQAPPPLA 731
PP + P+ P + PP L+ P P + P PPA P+S +T PP PPPL
Sbjct: 376 PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 435
Query: 732 APPLQVP-PSPPASPP---MSPSATPPPRVPP------LLAAPPLQVPP-----SPPASL 776
P P PS PA PP S + PPP P + PP P PP +
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
P P PP P A PP + S G + PL T + +
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS---------SCPLPTVQIKEEALDD 546
Query: 837 APLLQVPPSPPASPT 851
A + PP PP SP+
Sbjct: 547 AEEPESPPPPPRSPS 561
Score = 116 bits (290), Expect = 1e-25
Identities = 246/990 (24%), Positives = 326/990 (32%), Gaps = 161/990 (16%)
Query: 81 RSAGTSSRNPASRPPASGRGER----APPAKNTSPGPVSSPGR-----ASGTTRPGPLGQ 131
RS+G +S + AS + E A K + P+ S R AS T
Sbjct: 53 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 112
Query: 132 KGLR---ISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAMARRSRA 182
K + IS + + G+ + RS G+ +D +P PSP
Sbjct: 113 KKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 172
Query: 183 AGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
+ + + + P A P T P + + T P+P+A P G
Sbjct: 173 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG--------- 223
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQV-TPPRKDAAPALGP 298
+P +S A + P A P AP H + L RPP PP P L P
Sbjct: 224 ------SPTASQAPNQPQA---PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
Query: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP-SAPPSLQTL 357
L+ S +PS + PP P P +L P L P PP P PP
Sbjct: 275 LTGSAGQPSAPSHAQ----PPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQG 327
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
+P T P+ A P + +Q P S + Q P PP+PLA+ ++ +
Sbjct: 328 QAPLGTSPAAAYPHTS---LQLPASQSALQSQQPPR-----EQPLPPAPLAMPHIKPPPT 379
Query: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
P L A + + L+ PS P +LP PP PA+
Sbjct: 380 TPIPQLPAPQA------HKHPPHLSGPS----------PFSMNANLP--PP------PAL 415
Query: 478 SPLSSPLTIHPLQALSSLASHSPQA-PL-SSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
PLSS T HP A PQ+ PL SS PP TQS PP PPAS P
Sbjct: 416 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPAS---HPP 468
Query: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPSPLTTPPPETPSSIATPPPQA 594
L +AP P P + P P P P+ P P T+ PP P + A PP
Sbjct: 469 TGLHQVAPQP----------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 518
Query: 595 PPALASPPLQG----LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
A G LP+ + A + P ++PP PP SP P +P
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEP--------ESPPPPPRSPSPEPTVVDTP 570
Query: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
+ A F P A ++ + A +
Sbjct: 571 SHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 630
Query: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP-------MSPSATPPPRVPPLLAA 763
+ AA S P M PS PPP +AA
Sbjct: 631 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTT---IAA 687
Query: 764 PPLQVPPSPPASLPMSPLAKPPPQAP---------PALATPPLQALPSP------PASFP 808
P + P PA +S A+P +P P T PL A P P
Sbjct: 688 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 747
Query: 809 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-----PPTPGP 863
+ + P P P P A+P R PPT GP
Sbjct: 748 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 807
Query: 864 DTSVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP-EELRGY 914
S R LALA GP P S L+ + A +S TS P L+ +
Sbjct: 808 HPFASFHPGLNPLERERLALA-GPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMF 866
Query: 915 DSGPEGGAAASPPPDAELAACHPA-AWSRGPAPPLA---FRGAPGAPLPWPPATGPGSAD 970
+ P + L P S GP PL G A P+PP T P
Sbjct: 867 NVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 926
Query: 971 GLCTIYETE---GPESATPAPGALDPGPSP 997
G +E E P TP P L PG P
Sbjct: 927 GQ-PPHEHEMLRHPVFGTPYPRDL-PGAIP 954
Score = 111 bits (277), Expect = 4e-24
Identities = 124/408 (30%), Positives = 160/408 (39%), Gaps = 85/408 (20%)
Query: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPSQAPPSLAAPP 703
PSPQ + + Q P +QAP +P ++PP +P P P + A PP
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 221
Query: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
SP AS +P+ P AP P + +P P PS PPP P
Sbjct: 222 ---QGSPTAS--QAPNQPQAPTAP----VPHTHIQQAPALHPQRPPSPHPPPHPSP---H 269
Query: 764 PPLQVPPSPPASLPMSPL-AKPP-----PQAPPALATPPLQALPSPPASF-------PGQ 810
PPLQ P + A P +P A+PP P P +L PL P PP F GQ
Sbjct: 270 PPLQ-PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 328
Query: 811 APF--SPSASLPMSPLATP----------PPQAPPVLAAPL----LQVPPSPPAS--PTL 852
AP SP+A+ P + L P PP+ P+ APL ++ PP+ P P
Sbjct: 329 APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 388
Query: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
QA + PP +SGP ++ PPPP+ P S+LS H SA P +L
Sbjct: 389 QAHKHPP------HLSGPS-PFSMNANLPPPPALKPLSSLS----THHPPSAHPPPLQLM 437
Query: 913 GYDSGPEGGAAASPPPDAELA------ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966
S P + A PP + A HP AP F P P PP T P
Sbjct: 438 P-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 496
Query: 967 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014
P ++TP G PGTS +GA A S
Sbjct: 497 TC------------PSTSTPPAG-------PGTSAQPPCSGAAASGGS 525
Score = 89.4 bits (220), Expect = 2e-17
Identities = 200/831 (24%), Positives = 265/831 (31%), Gaps = 146/831 (17%)
Query: 104 PPA----KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159
PPA +P P S+P PGP AT P + + +A
Sbjct: 184 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS---------------ATAVPPQGSPTAS 228
Query: 160 -ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
A PT P + + P P P P PP + S S S
Sbjct: 229 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288
Query: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP--ARSGPSARGTPRAPAHPSQP---- 272
+P P + P LQ P P A G + GT A A+P
Sbjct: 289 QP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347
Query: 273 -KPKGLQALRPP--QVTPPRKDAAPALGPLSSSP---------------LATPSPSGTKA 314
LQ+ +PP Q PP A P + P ++P L+ PSP A
Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 407
Query: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLA--------PPSPSAPPSL---QTLPSPPAT 363
PPP A PL + PP A P PL P SP+ PP L Q LP PPA+
Sbjct: 408 NLPPPP--ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465
Query: 364 PP-------------SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
P +Q P PP PP T P P + S Q P S A S
Sbjct: 466 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPP---TCPSTSTPPAGPGTSAQPPCSGAAAS 522
Query: 411 --SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
S+ +S PT+Q L + + P P S P+ + P S
Sbjct: 523 GGSIAGGSSCPLPTVQIKEEALD----DAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 578
Query: 469 LQTSLSPAVSPLS-SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
L + + + L PL A S LA +A + + + +
Sbjct: 579 FYKHLDRGYNSCARTDLYFMPL-AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKE 637
Query: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP----ET 583
A L+ P L P P + PP+ + PP +T
Sbjct: 638 REREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDT 696
Query: 584 PSSIATPPPQAPPALASPPLQGLPS-PPLSP----LATPPP---QAPPXLALPPLQAPP- 634
P+ + T A P + SP + P PL+P LA P P + L+
Sbjct: 697 PA-LRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREI 755
Query: 635 --------------------SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
PP PL P A P A+ + P P
Sbjct: 756 REREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTI-----PPTAGPHPF 810
Query: 675 APFSPPASPP-------VSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPMSPSATP 722
A F P +P P P P LAA + S P + + TP
Sbjct: 811 ASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTP 870
Query: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPL 781
+ + L + P SA P P V PL A P L P PP +LP L
Sbjct: 871 HHHQHSHIHSH-LHLHQQDPLH---QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 926
Query: 782 AKPPPQ----APPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLA 825
+PP + P TP + LP PP S Q + S + LA
Sbjct: 927 GQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLA 977
Score = 78.2 bits (191), Expect = 4e-14
Identities = 118/459 (25%), Positives = 163/459 (35%), Gaps = 99/459 (21%)
Query: 14 ARTPAARAPGLLTPRP----PGSPR-PPPPVTPAALRV----LGAAGAVGRKPLA----- 59
A+ PA +AP +TP P PG+P+ P P TP+A V A +P A
Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 241
Query: 60 -----ERAGGIGGATIPESAPRAGP---------TRSAGTSSRNPASRPPASGRGERAPP 105
++A + P P P T SAG S ++PP G+G P
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 300
Query: 106 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 165
+ GP+ PGP GL A + +AP ++ A A TS
Sbjct: 301 -HSLQAGPLLQ--------HPGPPQPFGLPPQASQG-------QAPLGTS-PAAAYPHTS 343
Query: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--RPPTEGPRKSVSSASEHSTTEPSPA 223
P + S A +S+ E LP PAP A P +PP P + P+P
Sbjct: 344 LQLPASQS---ALQSQQPPREQPLP-PAPLAMPHIKPPPTTPIPQL----------PAPQ 389
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRP 282
A + P P SGPS P P+ L P
Sbjct: 390 AHKHP-----------------------PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
Query: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342
P PP P PL SSP P + ++ P PP + T L P P P
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486
Query: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ----APPSLQTIPPIQVPHSL--T 396
P P PP+ + +PPA P + A P + A S +P +Q+
Sbjct: 487 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 546
Query: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
+ ++PP P S + PT+ T S + S R
Sbjct: 547 AEEPESPPPPPRSPSPE-------PTVVDTPSHASQSAR 578
Score = 49.7 bits (117), Expect = 2e-05
Identities = 140/595 (23%), Positives = 187/595 (31%), Gaps = 113/595 (18%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
P L P S PP P L+++ + + P A+ G +P PT
Sbjct: 412 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP-AQPPGLTQSQNLPPPPASHPPTG 470
Query: 82 SAGTSSRNPASRPP--ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
+ + P ++ P G PP ++ P + PG ++ G G
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------ 524
Query: 140 ETVARGKATEAP----KRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGL 189
++A G + P K AL ++ P P +PSP + S++A L
Sbjct: 525 -SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 583
Query: 190 PRPAPSARPRP----PTEGPR--KSVSSASEHSTTEPSPAAR--------------RRPS 229
R S P G + K A E + E AR R
Sbjct: 584 DRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 643
Query: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
+R A S S+ LS P SGP PS P A PP + P
Sbjct: 644 REREAERAAKASSSAHEGRLSDPQLSGPGHM-------RPSFEPPPTTIAAVPPYIGPD- 695
Query: 290 KDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
PAL LS ARP V P N P L P+ PL P
Sbjct: 696 ---TPALRTLSEY-----------ARPHVMSPTNRNHPFYMPLNPTDPLLAYH--MPGLY 739
Query: 349 SAPPSLQTL----------------------PSPPATPPSQAPPSMTTPPMQ--APPSLQ 384
+ P+++ P PP P PM+ A S
Sbjct: 740 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 799
Query: 385 TIPPIQVPHSLTS--PSLQA-PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
TIPP PH S P L LAL+ Q + P A + ASL
Sbjct: 800 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHA----ERMASL 855
Query: 442 TSPSRPASTPPDSPP-------LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
TS + P + + L L PL + V PL PLT P A
Sbjct: 856 TSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFP 915
Query: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
+ PL L PP E + P TP +LP PPP+ A
Sbjct: 916 YPPGTLPNPL--LGQPPHEHEMLRHPV--------FGTPYPRDLPGAIPPPMSAA 960
Score = 43.9 bits (102), Expect = 9e-04
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 859
PS P+ ++ SA M P QAP V AP +PP +P L P
Sbjct: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 208
Query: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919
TPGP S + A+ P P S++P+ + H+ + P+
Sbjct: 209 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 255
Query: 920 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 974
+ PPP HP+ P PPL G P AP PP G G
Sbjct: 256 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 298
Query: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034
GP S P PGP P G P QA G+ PLG A+
Sbjct: 299 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 338
Query: 1035 VQHLLSRTLLLAAAEGA 1051
H +L L A++ A
Sbjct: 339 YPH---TSLQLPASQSA 352
Score = 40.8 bits (94), Expect = 0.007
Identities = 131/592 (22%), Positives = 193/592 (32%), Gaps = 110/592 (18%)
Query: 70 IPESAPR-AGPTRSAG-TSSRN----PASRPPASGRGERAP-------PAKNTSPGPVSS 116
+P+S P + P + G T S+N PAS PP +G + AP P P P++
Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP-TGLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSGPTPGTPSPA 175
P S +T P G T A P S +A G + P+
Sbjct: 496 PTCPSTSTPPA-----------------GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 538
Query: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS----EHSTTEPSPAARR----R 227
+ + E P P P + PT S +S S +H + AR
Sbjct: 539 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 598
Query: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
P AG L + ++ + AR + K K + R +
Sbjct: 599 PLAGSKLAKKREEAIEKAKREAEQKARE------------EREREKEKEKERERERERER 646
Query: 288 PRKDAAPALGPLSSSPLATPSPSGT-KARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
+ AA A L+ P SG RP + P P T+ PP P
Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRP------SFEPPPTTIAAVPPYIGP------ 694
Query: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
P+L+TL A P + +P + P + P + P L
Sbjct: 695 ---DTPALRTLSE-------YARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPT 744
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPR-QTQASLTSPSRPASTPPDSPPLQAPLSLP- 464
+ L+ + ++ M P + + P PA+ P + + L++P
Sbjct: 745 IRERELRER-EIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPP 803
Query: 465 -ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
A P S P ++PL LA PQ + P + LA +
Sbjct: 804 TAGPHPFASFHPGLNPLER----------ERLALAGPQ------LRPEMSYPDRLAAERI 847
Query: 524 QTPP-ASLTTPPLENLPSLAPPPLQTASAPLTTP-HLET----------PPCPAPCPLQA 571
ASLT+ PL L P + + + HL P P PL A
Sbjct: 848 HAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTA 907
Query: 572 PP--SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
P + PP P+ + PP L P G P P P A PPP +
Sbjct: 908 GPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVF-GTPYPRDLPGAIPPPMS 958
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 154 bits (388), Expect = 6e-37
Identities = 145/442 (32%), Positives = 181/442 (40%), Gaps = 60/442 (13%)
Query: 513 ETQSSLAPPSLQTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLET-PPCPAPCPLQ 570
++ SS LQ P +L P + PS APP P TP PP +P Q
Sbjct: 724 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ 783
Query: 571 APPSPLTTPPPETPSSIATPP---PQAPPALASPPLQGLPSPPLSPLATPPPQ-APPXLA 626
AP P P + I P PQ PP+ PP P PPL PL Q + P A
Sbjct: 784 APNQPQAPTAPVPHTHIQQAPALHPQRPPS-PHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 627 LPPL--QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPAS 682
PPL Q PP P + L P P P L PP + QAP SP A+
Sbjct: 843 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL----------PPQASQGQAPLGTSPAAA 892
Query: 683 PPVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPP-PQAPPPLAA--PPLQV 737
P + P SQ+ PP + +PP+P A P + P T P PQ P P A PP
Sbjct: 893 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952
Query: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP- 796
PSP + M+ + PPP + PL + P + P L + P ++P P +P A PP
Sbjct: 953 GPSPFS---MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---AQPPG 1006
Query: 797 ---LQALPSPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPT 851
Q LP PPAS P P P P A P P PP + P +PPA P
Sbjct: 1007 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063
Query: 852 LQAPRRPPTPG----------------PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
A +PP G P + L A P PPPP RSPS +
Sbjct: 1064 TSA--QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 1121
Query: 896 DLAGHSSSATSTPEEL-RGYDS 916
D H+S + + L RGY+S
Sbjct: 1122 DTPSHASQSARFYKHLDRGYNS 1143
Score = 134 bits (338), Expect = 4e-31
Identities = 174/637 (27%), Positives = 226/637 (35%), Gaps = 93/637 (14%)
Query: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
RRSR + + + R A P T + + S+ +S + S ++ S +++
Sbjct: 575 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN--DSKAETVKKS 632
Query: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
A + +++PL S R S K K + RP +P+ G
Sbjct: 633 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPN---------SPSEG 683
Query: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
SS + + G+ DN +T SP + +P S S+
Sbjct: 684 EGESSDSRSVNDEGSSDPKDIDQDNRST--------SPSIPSPQDNESDSDSSAQQQMLQ 735
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATT 416
PPA QAP +T P APP +P L P P+P S A
Sbjct: 736 AQPPAL---QAPTGVTPAPSSAPPG--------------TPQLPTPGPTP----SATAVP 774
Query: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
GSPT + +P Q QA P + P + QAP P PP SP
Sbjct: 775 PQGSPTA-------SQAPNQPQA-------PTAPVPHTHIQQAPALHPQRPP-----SPH 815
Query: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
P SP PLQ L+ A P AP S PPL Q P SLQ P L P
Sbjct: 816 PPPHPSPHP--PLQPLTGSAGQ-PSAP--SHAQPPLHGQGPPGPHSLQAGP--LLQHPGP 868
Query: 537 NLPSLAPPPLQTASAPL-TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
P PP APL T+P P P PP E P P P A
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP---LPPAPLAM 925
Query: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655
P + PP +P P PP P PPA PLS L+T P P+A
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP--PSA 983
Query: 656 LAVHLLQAPFSPP-PSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPP----- 708
L P S P PS P Q P + + P P++ PP+ PP P
Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Query: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
PP +PP PS + PP P A PP + S S P A +
Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103
Query: 769 PPSPPASLPMSPLAKPPPQAP---PALATPPLQALPS 802
P SPP PPP++P P + P A S
Sbjct: 1104 PESPP----------PPPRSPSPEPTVVDTPSHASQS 1130
Score = 121 bits (303), Expect = 4e-27
Identities = 132/435 (30%), Positives = 158/435 (36%), Gaps = 61/435 (14%)
Query: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
ST P P Q S S Q L L +P + P A SS +PQ P
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTP--APSSAPPGTPQLPT---- 763
Query: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
P T S+ A P +P AS P P+ P AP P P P P P
Sbjct: 764 --PGPTPSATAVPPQGSPTAS-QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 820
Query: 569 LQAPP-SPLT--TPPPETPSSIATPP-----PQAPPALASPPLQGLPSPPLSPLATPPP- 619
PP PLT P PS A PP P P +L + PL P PP P PP
Sbjct: 821 SPHPPLQPLTGSAGQPSAPSH-AQPPLHGQGPPGPHSLQAGPLLQHPGPP-QPFGLPPQA 878
Query: 620 -QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Q L P A P P S A S Q P + PP+P
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL---------PPAPLAMPHIK 929
Query: 679 PPASPPVSPSATPPSQA-PPSLAAP-PLQVP---PSPPASPPMSPSAT--PPPQAPPPLA 731
PP + P+ P + PP L+ P P + P PPA P+S +T PP PPPL
Sbjct: 930 PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 989
Query: 732 APPLQVP-PSPPASPP---MSPSATPPPRVPP------LLAAPPLQVPP-----SPPASL 776
P P PS PA PP S + PPP P + PP P PP +
Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
P P PP P A PP + S G + PL T + +
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS---------SCPLPTVQIKEEALDD 1100
Query: 837 APLLQVPPSPPASPT 851
A + PP PP SP+
Sbjct: 1101 AEEPESPPPPPRSPS 1115
Score = 116 bits (290), Expect = 1e-25
Identities = 246/990 (24%), Positives = 326/990 (32%), Gaps = 161/990 (16%)
Query: 81 RSAGTSSRNPASRPPASGRGER----APPAKNTSPGPVSSPGR-----ASGTTRPGPLGQ 131
RS+G +S + AS + E A K + P+ S R AS T
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 666
Query: 132 KGLR---ISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAMARRSRA 182
K + IS + + G+ + RS G+ +D +P PSP
Sbjct: 667 KKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 726
Query: 183 AGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
+ + + + P A P T P + + T P+P+A P G
Sbjct: 727 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG--------- 777
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQV-TPPRKDAAPALGP 298
+P +S A + P A P AP H + L RPP PP P L P
Sbjct: 778 ------SPTASQAPNQPQA---PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP-SAPPSLQTL 357
L+ S +PS + PP P P +L P L P PP P PP
Sbjct: 829 LTGSAGQPSAPSHAQ----PPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQG 881
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
+P T P+ A P + +Q P S + Q P PP+PLA+ ++ +
Sbjct: 882 QAPLGTSPAAAYPHTS---LQLPASQSALQSQQPPR-----EQPLPPAPLAMPHIKPPPT 933
Query: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
P L A + + L+ PS P +LP PP PA+
Sbjct: 934 TPIPQLPAPQA------HKHPPHLSGPS----------PFSMNANLP--PP------PAL 969
Query: 478 SPLSSPLTIHPLQALSSLASHSPQA-PL-SSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
PLSS T HP A PQ+ PL SS PP TQS PP PPAS P
Sbjct: 970 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPAS---HPP 1022
Query: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPSPLTTPPPETPSSIATPPPQA 594
L +AP P P + P P P P+ P P T+ PP P + A PP
Sbjct: 1023 TGLHQVAPQP----------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 595 PPALASPPLQG----LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
A G LP+ + A + P ++PP PP SP P +P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEP--------ESPPPPPRSPSPEPTVVDTP 1124
Query: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
+ A F P A ++ + A +
Sbjct: 1125 SHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 1184
Query: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP-------MSPSATPPPRVPPLLAA 763
+ AA S P M PS PPP +AA
Sbjct: 1185 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTT---IAA 1241
Query: 764 PPLQVPPSPPASLPMSPLAKPPPQAP---------PALATPPLQALPSP------PASFP 808
P + P PA +S A+P +P P T PL A P P
Sbjct: 1242 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 1301
Query: 809 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-----PPTPGP 863
+ + P P P P A+P R PPT GP
Sbjct: 1302 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 1361
Query: 864 DTSVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP-EELRGY 914
S R LALA GP P S L+ + A +S TS P L+ +
Sbjct: 1362 HPFASFHPGLNPLERERLALA-GPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMF 1420
Query: 915 DSGPEGGAAASPPPDAELAACHPA-AWSRGPAPPLA---FRGAPGAPLPWPPATGPGSAD 970
+ P + L P S GP PL G A P+PP T P
Sbjct: 1421 NVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 1480
Query: 971 GLCTIYETE---GPESATPAPGALDPGPSP 997
G +E E P TP P L PG P
Sbjct: 1481 GQ-PPHEHEMLRHPVFGTPYPRDL-PGAIP 1508
Score = 111 bits (277), Expect = 4e-24
Identities = 124/408 (30%), Positives = 160/408 (39%), Gaps = 85/408 (20%)
Query: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPSQAPPSLAAPP 703
PSPQ + + Q P +QAP +P ++PP +P P P + A PP
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775
Query: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
SP AS +P+ P AP P + +P P PS PPP P
Sbjct: 776 ---QGSPTAS--QAPNQPQAPTAP----VPHTHIQQAPALHPQRPPSPHPPPHPSP---H 823
Query: 764 PPLQVPPSPPASLPMSPL-AKPP-----PQAPPALATPPLQALPSPPASF-------PGQ 810
PPLQ P + A P +P A+PP P P +L PL P PP F GQ
Sbjct: 824 PPLQ-PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882
Query: 811 APF--SPSASLPMSPLATP----------PPQAPPVLAAPL----LQVPPSPPAS--PTL 852
AP SP+A+ P + L P PP+ P+ APL ++ PP+ P P
Sbjct: 883 APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942
Query: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
QA + PP +SGP ++ PPPP+ P S+LS H SA P +L
Sbjct: 943 QAHKHPP------HLSGPS-PFSMNANLPPPPALKPLSSLS----THHPPSAHPPPLQLM 991
Query: 913 GYDSGPEGGAAASPPPDAELA------ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966
S P + A PP + A HP AP F P P PP T P
Sbjct: 992 P-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050
Query: 967 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014
P ++TP G PGTS +GA A S
Sbjct: 1051 TC------------PSTSTPPAG-------PGTSAQPPCSGAAASGGS 1079
Score = 89.4 bits (220), Expect = 2e-17
Identities = 200/831 (24%), Positives = 265/831 (31%), Gaps = 146/831 (17%)
Query: 104 PPA----KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159
PPA +P P S+P PGP AT P + + +A
Sbjct: 738 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS---------------ATAVPPQGSPTAS 782
Query: 160 -ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
A PT P + + P P P P PP + S S S
Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP--ARSGPSARGTPRAPAHPSQP---- 272
+P P + P LQ P P A G + GT A A+P
Sbjct: 843 QP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901
Query: 273 -KPKGLQALRPP--QVTPPRKDAAPALGPLSSSP---------------LATPSPSGTKA 314
LQ+ +PP Q PP A P + P ++P L+ PSP A
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 961
Query: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLA--------PPSPSAPPSL---QTLPSPPAT 363
PPP A PL + PP A P PL P SP+ PP L Q LP PPA+
Sbjct: 962 NLPPPP--ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019
Query: 364 PP-------------SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
P +Q P PP PP T P P + S Q P S A S
Sbjct: 1020 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPP---TCPSTSTPPAGPGTSAQPPCSGAAAS 1076
Query: 411 --SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
S+ +S PT+Q L + + P P S P+ + P S
Sbjct: 1077 GGSIAGGSSCPLPTVQIKEEALD----DAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 1132
Query: 469 LQTSLSPAVSPLS-SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
L + + + L PL A S LA +A + + + +
Sbjct: 1133 FYKHLDRGYNSCARTDLYFMPL-AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKE 1191
Query: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP----ET 583
A L+ P L P P + PP+ + PP +T
Sbjct: 1192 REREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDT 1250
Query: 584 PSSIATPPPQAPPALASPPLQGLPS-PPLSP----LATPPP---QAPPXLALPPLQAPP- 634
P+ + T A P + SP + P PL+P LA P P + L+
Sbjct: 1251 PA-LRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREI 1309
Query: 635 --------------------SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
PP PL P A P A+ + P P
Sbjct: 1310 REREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTI-----PPTAGPHPF 1364
Query: 675 APFSPPASPP-------VSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPMSPSATP 722
A F P +P P P P LAA + S P + + TP
Sbjct: 1365 ASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTP 1424
Query: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPL 781
+ + L + P SA P P V PL A P L P PP +LP L
Sbjct: 1425 HHHQHSHIHSH-LHLHQQDPLH---QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 1480
Query: 782 AKPPPQ----APPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLA 825
+PP + P TP + LP PP S Q + S + LA
Sbjct: 1481 GQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLA 1531
Score = 78.2 bits (191), Expect = 4e-14
Identities = 118/459 (25%), Positives = 163/459 (35%), Gaps = 99/459 (21%)
Query: 14 ARTPAARAPGLLTPRP----PGSPR-PPPPVTPAALRV----LGAAGAVGRKPLA----- 59
A+ PA +AP +TP P PG+P+ P P TP+A V A +P A
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 795
Query: 60 -----ERAGGIGGATIPESAPRAGP---------TRSAGTSSRNPASRPPASGRGERAPP 105
++A + P P P T SAG S ++PP G+G P
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 854
Query: 106 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 165
+ GP+ PGP GL A + +AP ++ A A TS
Sbjct: 855 -HSLQAGPLLQ--------HPGPPQPFGLPPQASQG-------QAPLGTS-PAAAYPHTS 897
Query: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--RPPTEGPRKSVSSASEHSTTEPSPA 223
P + S A +S+ E LP PAP A P +PP P + P+P
Sbjct: 898 LQLPASQS---ALQSQQPPREQPLP-PAPLAMPHIKPPPTTPIPQL----------PAPQ 943
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRP 282
A + P P SGPS P P+ L P
Sbjct: 944 AHKHP-----------------------PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Query: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342
P PP P PL SSP P + ++ P PP + T L P P P
Sbjct: 981 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ----APPSLQTIPPIQVPHSL--T 396
P P PP+ + +PPA P + A P + A S +P +Q+
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 1100
Query: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
+ ++PP P S + PT+ T S + S R
Sbjct: 1101 AEEPESPPPPPRSPSPE-------PTVVDTPSHASQSAR 1132
Score = 49.7 bits (117), Expect = 2e-05
Identities = 140/595 (23%), Positives = 187/595 (31%), Gaps = 113/595 (18%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
P L P S PP P L+++ + + P A+ G +P PT
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP-AQPPGLTQSQNLPPPPASHPPTG 1024
Query: 82 SAGTSSRNPASRPP--ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
+ + P ++ P G PP ++ P + PG ++ G G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------ 1078
Query: 140 ETVARGKATEAP----KRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGL 189
++A G + P K AL ++ P P +PSP + S++A L
Sbjct: 1079 -SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137
Query: 190 PRPAPSARPRP----PTEGPR--KSVSSASEHSTTEPSPAAR--------------RRPS 229
R S P G + K A E + E AR R
Sbjct: 1138 DRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 1197
Query: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
+R A S S+ LS P SGP PS P A PP + P
Sbjct: 1198 REREAERAAKASSSAHEGRLSDPQLSGPGHM-------RPSFEPPPTTIAAVPPYIGPD- 1249
Query: 290 KDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
PAL LS ARP V P N P L P+ PL P
Sbjct: 1250 ---TPALRTLSEY-----------ARPHVMSPTNRNHPFYMPLNPTDPLLAYH--MPGLY 1293
Query: 349 SAPPSLQTL----------------------PSPPATPPSQAPPSMTTPPMQ--APPSLQ 384
+ P+++ P PP P PM+ A S
Sbjct: 1294 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 1353
Query: 385 TIPPIQVPHSLTS--PSLQA-PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
TIPP PH S P L LAL+ Q + P A + ASL
Sbjct: 1354 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHA----ERMASL 1409
Query: 442 TSPSRPASTPPDSPP-------LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
TS + P + + L L PL + V PL PLT P A
Sbjct: 1410 TSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFP 1469
Query: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
+ PL L PP E + P TP +LP PPP+ A
Sbjct: 1470 YPPGTLPNPL--LGQPPHEHEMLRHPV--------FGTPYPRDLPGAIPPPMSAA 1514
Score = 43.9 bits (102), Expect = 9e-04
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 859
PS P+ ++ SA M P QAP V AP +PP +P L P
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 762
Query: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919
TPGP S + A+ P P S++P+ + H+ + P+
Sbjct: 763 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 809
Query: 920 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 974
+ PPP HP+ P PPL G P AP PP G G
Sbjct: 810 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 852
Query: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034
GP S P PGP P G P QA G+ PLG A+
Sbjct: 853 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 892
Query: 1035 VQHLLSRTLLLAAAEGA 1051
H +L L A++ A
Sbjct: 893 YPH---TSLQLPASQSA 906
Score = 40.8 bits (94), Expect = 0.007
Identities = 131/592 (22%), Positives = 193/592 (32%), Gaps = 110/592 (18%)
Query: 70 IPESAPR-AGPTRSAG-TSSRN----PASRPPASGRGERAP-------PAKNTSPGPVSS 116
+P+S P + P + G T S+N PAS PP +G + AP P P P++
Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP-TGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSGPTPGTPSPA 175
P S +T P G T A P S +A G + P+
Sbjct: 1050 PTCPSTSTPPA-----------------GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 1092
Query: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS----EHSTTEPSPAARR----R 227
+ + E P P P + PT S +S S +H + AR
Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 1152
Query: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
P AG L + ++ + AR + K K + R +
Sbjct: 1153 PLAGSKLAKKREEAIEKAKREAEQKARE------------EREREKEKEKERERERERER 1200
Query: 288 PRKDAAPALGPLSSSPLATPSPSGT-KARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
+ AA A L+ P SG RP + P P T+ PP P
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRP------SFEPPPTTIAAVPPYIGP------ 1248
Query: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
P+L+TL A P + +P + P + P + P L
Sbjct: 1249 ---DTPALRTLSE-------YARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPT 1298
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPR-QTQASLTSPSRPASTPPDSPPLQAPLSLP- 464
+ L+ + ++ M P + + P PA+ P + + L++P
Sbjct: 1299 IRERELRER-EIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPP 1357
Query: 465 -ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
A P S P ++PL LA PQ + P + LA +
Sbjct: 1358 TAGPHPFASFHPGLNPLER----------ERLALAGPQ------LRPEMSYPDRLAAERI 1401
Query: 524 QTPP-ASLTTPPLENLPSLAPPPLQTASAPLTTP-HLET----------PPCPAPCPLQA 571
ASLT+ PL L P + + + HL P P PL A
Sbjct: 1402 HAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTA 1461
Query: 572 PP--SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
P + PP P+ + PP L P G P P P A PPP +
Sbjct: 1462 GPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVF-GTPYPRDLPGAIPPPMS 1512
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 154 bits (388), Expect = 6e-37
Identities = 145/442 (32%), Positives = 181/442 (40%), Gaps = 60/442 (13%)
Query: 513 ETQSSLAPPSLQTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLET-PPCPAPCPLQ 570
++ SS LQ P +L P + PS APP P TP PP +P Q
Sbjct: 724 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ 783
Query: 571 APPSPLTTPPPETPSSIATPP---PQAPPALASPPLQGLPSPPLSPLATPPPQ-APPXLA 626
AP P P + I P PQ PP+ PP P PPL PL Q + P A
Sbjct: 784 APNQPQAPTAPVPHTHIQQAPALHPQRPPS-PHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 627 LPPL--QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPAS 682
PPL Q PP P + L P P P L PP + QAP SP A+
Sbjct: 843 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL----------PPQASQGQAPLGTSPAAA 892
Query: 683 PPVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPP-PQAPPPLAA--PPLQV 737
P + P SQ+ PP + +PP+P A P + P T P PQ P P A PP
Sbjct: 893 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952
Query: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP- 796
PSP + M+ + PPP + PL + P + P L + P ++P P +P A PP
Sbjct: 953 GPSPFS---MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---AQPPG 1006
Query: 797 ---LQALPSPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPT 851
Q LP PPAS P P P P A P P PP + P +PPA P
Sbjct: 1007 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063
Query: 852 LQAPRRPPTPG----------------PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
A +PP G P + L A P PPPP RSPS +
Sbjct: 1064 TSA--QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 1121
Query: 896 DLAGHSSSATSTPEEL-RGYDS 916
D H+S + + L RGY+S
Sbjct: 1122 DTPSHASQSARFYKHLDRGYNS 1143
Score = 134 bits (338), Expect = 4e-31
Identities = 174/637 (27%), Positives = 226/637 (35%), Gaps = 93/637 (14%)
Query: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
RRSR + + + R A P T + + S+ +S + S ++ S +++
Sbjct: 575 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN--DSKAETVKKS 632
Query: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
A + +++PL S R S K K + RP +P+ G
Sbjct: 633 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPN---------SPSEG 683
Query: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
SS + + G+ DN +T SP + +P S S+
Sbjct: 684 EGESSDSRSVNDEGSSDPKDIDQDNRST--------SPSIPSPQDNESDSDSSAQQQMLQ 735
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATT 416
PPA QAP +T P APP +P L P P+P S A
Sbjct: 736 AQPPAL---QAPTGVTPAPSSAPPG--------------TPQLPTPGPTP----SATAVP 774
Query: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
GSPT + +P Q QA P + P + QAP P PP SP
Sbjct: 775 PQGSPTA-------SQAPNQPQA-------PTAPVPHTHIQQAPALHPQRPP-----SPH 815
Query: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
P SP PLQ L+ A P AP S PPL Q P SLQ P L P
Sbjct: 816 PPPHPSPHP--PLQPLTGSAGQ-PSAP--SHAQPPLHGQGPPGPHSLQAGP--LLQHPGP 868
Query: 537 NLPSLAPPPLQTASAPL-TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
P PP APL T+P P P PP E P P P A
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP---LPPAPLAM 925
Query: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655
P + PP +P P PP P PPA PLS L+T P P+A
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP--PSA 983
Query: 656 LAVHLLQAPFSPP-PSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPP----- 708
L P S P PS P Q P + + P P++ PP+ PP P
Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Query: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
PP +PP PS + PP P A PP + S S P A +
Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103
Query: 769 PPSPPASLPMSPLAKPPPQAP---PALATPPLQALPS 802
P SPP PPP++P P + P A S
Sbjct: 1104 PESPP----------PPPRSPSPEPTVVDTPSHASQS 1130
Score = 121 bits (303), Expect = 4e-27
Identities = 132/435 (30%), Positives = 158/435 (36%), Gaps = 61/435 (14%)
Query: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
ST P P Q S S Q L L +P + P A SS +PQ P
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTP--APSSAPPGTPQLPT---- 763
Query: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
P T S+ A P +P AS P P+ P AP P P P P P
Sbjct: 764 --PGPTPSATAVPPQGSPTAS-QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 820
Query: 569 LQAPP-SPLT--TPPPETPSSIATPP-----PQAPPALASPPLQGLPSPPLSPLATPPP- 619
PP PLT P PS A PP P P +L + PL P PP P PP
Sbjct: 821 SPHPPLQPLTGSAGQPSAPSH-AQPPLHGQGPPGPHSLQAGPLLQHPGPP-QPFGLPPQA 878
Query: 620 -QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Q L P A P P S A S Q P + PP+P
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL---------PPAPLAMPHIK 929
Query: 679 PPASPPVSPSATPPSQA-PPSLAAP-PLQVP---PSPPASPPMSPSAT--PPPQAPPPLA 731
PP + P+ P + PP L+ P P + P PPA P+S +T PP PPPL
Sbjct: 930 PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 989
Query: 732 APPLQVP-PSPPASPP---MSPSATPPPRVPP------LLAAPPLQVPP-----SPPASL 776
P P PS PA PP S + PPP P + PP P PP +
Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
P P PP P A PP + S G + PL T + +
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS---------SCPLPTVQIKEEALDD 1100
Query: 837 APLLQVPPSPPASPT 851
A + PP PP SP+
Sbjct: 1101 AEEPESPPPPPRSPS 1115
Score = 116 bits (290), Expect = 1e-25
Identities = 246/990 (24%), Positives = 326/990 (32%), Gaps = 161/990 (16%)
Query: 81 RSAGTSSRNPASRPPASGRGER----APPAKNTSPGPVSSPGR-----ASGTTRPGPLGQ 131
RS+G +S + AS + E A K + P+ S R AS T
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 666
Query: 132 KGLR---ISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAMARRSRA 182
K + IS + + G+ + RS G+ +D +P PSP
Sbjct: 667 KKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 726
Query: 183 AGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
+ + + + P A P T P + + T P+P+A P G
Sbjct: 727 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG--------- 777
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQV-TPPRKDAAPALGP 298
+P +S A + P A P AP H + L RPP PP P L P
Sbjct: 778 ------SPTASQAPNQPQA---PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP-SAPPSLQTL 357
L+ S +PS + PP P P +L P L P PP P PP
Sbjct: 829 LTGSAGQPSAPSHAQ----PPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQG 881
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
+P T P+ A P + +Q P S + Q P PP+PLA+ ++ +
Sbjct: 882 QAPLGTSPAAAYPHTS---LQLPASQSALQSQQPPR-----EQPLPPAPLAMPHIKPPPT 933
Query: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
P L A + + L+ PS P +LP PP PA+
Sbjct: 934 TPIPQLPAPQA------HKHPPHLSGPS----------PFSMNANLP--PP------PAL 969
Query: 478 SPLSSPLTIHPLQALSSLASHSPQA-PL-SSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
PLSS T HP A PQ+ PL SS PP TQS PP PPAS P
Sbjct: 970 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPAS---HPP 1022
Query: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPSPLTTPPPETPSSIATPPPQA 594
L +AP P P + P P P P+ P P T+ PP P + A PP
Sbjct: 1023 TGLHQVAPQP----------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 595 PPALASPPLQG----LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
A G LP+ + A + P ++PP PP SP P +P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEP--------ESPPPPPRSPSPEPTVVDTP 1124
Query: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
+ A F P A ++ + A +
Sbjct: 1125 SHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREERER 1184
Query: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP-------MSPSATPPPRVPPLLAA 763
+ AA S P M PS PPP +AA
Sbjct: 1185 EKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTT---IAA 1241
Query: 764 PPLQVPPSPPASLPMSPLAKPPPQAP---------PALATPPLQALPSP------PASFP 808
P + P PA +S A+P +P P T PL A P P
Sbjct: 1242 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 1301
Query: 809 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-----PPTPGP 863
+ + P P P P A+P R PPT GP
Sbjct: 1302 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 1361
Query: 864 DTSVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP-EELRGY 914
S R LALA GP P S L+ + A +S TS P L+ +
Sbjct: 1362 HPFASFHPGLNPLERERLALA-GPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMF 1420
Query: 915 DSGPEGGAAASPPPDAELAACHPA-AWSRGPAPPLA---FRGAPGAPLPWPPATGPGSAD 970
+ P + L P S GP PL G A P+PP T P
Sbjct: 1421 NVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 1480
Query: 971 GLCTIYETE---GPESATPAPGALDPGPSP 997
G +E E P TP P L PG P
Sbjct: 1481 GQ-PPHEHEMLRHPVFGTPYPRDL-PGAIP 1508
Score = 111 bits (277), Expect = 4e-24
Identities = 124/408 (30%), Positives = 160/408 (39%), Gaps = 85/408 (20%)
Query: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPSQAPPSLAAPP 703
PSPQ + + Q P +QAP +P ++PP +P P P + A PP
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775
Query: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
SP AS +P+ P AP P + +P P PS PPP P
Sbjct: 776 ---QGSPTAS--QAPNQPQAPTAP----VPHTHIQQAPALHPQRPPSPHPPPHPSP---H 823
Query: 764 PPLQVPPSPPASLPMSPL-AKPP-----PQAPPALATPPLQALPSPPASF-------PGQ 810
PPLQ P + A P +P A+PP P P +L PL P PP F GQ
Sbjct: 824 PPLQ-PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882
Query: 811 APF--SPSASLPMSPLATP----------PPQAPPVLAAPL----LQVPPSPPAS--PTL 852
AP SP+A+ P + L P PP+ P+ APL ++ PP+ P P
Sbjct: 883 APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942
Query: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
QA + PP +SGP ++ PPPP+ P S+LS H SA P +L
Sbjct: 943 QAHKHPP------HLSGPS-PFSMNANLPPPPALKPLSSLS----THHPPSAHPPPLQLM 991
Query: 913 GYDSGPEGGAAASPPPDAELA------ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966
S P + A PP + A HP AP F P P PP T P
Sbjct: 992 P-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050
Query: 967 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014
P ++TP G PGTS +GA A S
Sbjct: 1051 TC------------PSTSTPPAG-------PGTSAQPPCSGAAASGGS 1079
Score = 89.4 bits (220), Expect = 2e-17
Identities = 200/831 (24%), Positives = 265/831 (31%), Gaps = 146/831 (17%)
Query: 104 PPA----KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159
PPA +P P S+P PGP AT P + + +A
Sbjct: 738 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS---------------ATAVPPQGSPTAS 782
Query: 160 -ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
A PT P + + P P P P PP + S S S
Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP--ARSGPSARGTPRAPAHPSQP---- 272
+P P + P LQ P P A G + GT A A+P
Sbjct: 843 QP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901
Query: 273 -KPKGLQALRPP--QVTPPRKDAAPALGPLSSSP---------------LATPSPSGTKA 314
LQ+ +PP Q PP A P + P ++P L+ PSP A
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 961
Query: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLA--------PPSPSAPPSL---QTLPSPPAT 363
PPP A PL + PP A P PL P SP+ PP L Q LP PPA+
Sbjct: 962 NLPPPP--ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019
Query: 364 PP-------------SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
P +Q P PP PP T P P + S Q P S A S
Sbjct: 1020 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPP---TCPSTSTPPAGPGTSAQPPCSGAAAS 1076
Query: 411 --SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
S+ +S PT+Q L + + P P S P+ + P S
Sbjct: 1077 GGSIAGGSSCPLPTVQIKEEALD----DAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 1132
Query: 469 LQTSLSPAVSPLS-SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
L + + + L PL A S LA +A + + + +
Sbjct: 1133 FYKHLDRGYNSCARTDLYFMPL-AGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKE 1191
Query: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP----ET 583
A L+ P L P P + PP+ + PP +T
Sbjct: 1192 REREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDT 1250
Query: 584 PSSIATPPPQAPPALASPPLQGLPS-PPLSP----LATPPP---QAPPXLALPPLQAPP- 634
P+ + T A P + SP + P PL+P LA P P + L+
Sbjct: 1251 PA-LRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREI 1309
Query: 635 --------------------SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
PP PL P A P A+ + P P
Sbjct: 1310 REREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTI-----PPTAGPHPF 1364
Query: 675 APFSPPASPP-------VSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPMSPSATP 722
A F P +P P P P LAA + S P + + TP
Sbjct: 1365 ASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTP 1424
Query: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPL 781
+ + L + P SA P P V PL A P L P PP +LP L
Sbjct: 1425 HHHQHSHIHSH-LHLHQQDPLH---QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLL 1480
Query: 782 AKPPPQ----APPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLA 825
+PP + P TP + LP PP S Q + S + LA
Sbjct: 1481 GQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLA 1531
Score = 78.2 bits (191), Expect = 4e-14
Identities = 118/459 (25%), Positives = 163/459 (35%), Gaps = 99/459 (21%)
Query: 14 ARTPAARAPGLLTPRP----PGSPR-PPPPVTPAALRV----LGAAGAVGRKPLA----- 59
A+ PA +AP +TP P PG+P+ P P TP+A V A +P A
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 795
Query: 60 -----ERAGGIGGATIPESAPRAGP---------TRSAGTSSRNPASRPPASGRGERAPP 105
++A + P P P T SAG S ++PP G+G P
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP- 854
Query: 106 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 165
+ GP+ PGP GL A + +AP ++ A A TS
Sbjct: 855 -HSLQAGPLLQ--------HPGPPQPFGLPPQASQG-------QAPLGTS-PAAAYPHTS 897
Query: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--RPPTEGPRKSVSSASEHSTTEPSPA 223
P + S A +S+ E LP PAP A P +PP P + P+P
Sbjct: 898 LQLPASQS---ALQSQQPPREQPLP-PAPLAMPHIKPPPTTPIPQL----------PAPQ 943
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRP 282
A + P P SGPS P P+ L P
Sbjct: 944 AHKHP-----------------------PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Query: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342
P PP P PL SSP P + ++ P PP + T L P P P
Sbjct: 981 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ----APPSLQTIPPIQVPHSL--T 396
P P PP+ + +PPA P + A P + A S +P +Q+
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 1100
Query: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
+ ++PP P S + PT+ T S + S R
Sbjct: 1101 AEEPESPPPPPRSPSPE-------PTVVDTPSHASQSAR 1132
Score = 49.7 bits (117), Expect = 2e-05
Identities = 140/595 (23%), Positives = 187/595 (31%), Gaps = 113/595 (18%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
P L P S PP P L+++ + + P A+ G +P PT
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP-AQPPGLTQSQNLPPPPASHPPTG 1024
Query: 82 SAGTSSRNPASRPP--ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
+ + P ++ P G PP ++ P + PG ++ G G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------ 1078
Query: 140 ETVARGKATEAP----KRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGL 189
++A G + P K AL ++ P P +PSP + S++A L
Sbjct: 1079 -SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137
Query: 190 PRPAPSARPRP----PTEGPR--KSVSSASEHSTTEPSPAAR--------------RRPS 229
R S P G + K A E + E AR R
Sbjct: 1138 DRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 1197
Query: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
+R A S S+ LS P SGP PS P A PP + P
Sbjct: 1198 REREAERAAKASSSAHEGRLSDPQLSGPGHM-------RPSFEPPPTTIAAVPPYIGPD- 1249
Query: 290 KDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
PAL LS ARP V P N P L P+ PL P
Sbjct: 1250 ---TPALRTLSEY-----------ARPHVMSPTNRNHPFYMPLNPTDPLLAYH--MPGLY 1293
Query: 349 SAPPSLQTL----------------------PSPPATPPSQAPPSMTTPPMQ--APPSLQ 384
+ P+++ P PP P PM+ A S
Sbjct: 1294 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 1353
Query: 385 TIPPIQVPHSLTS--PSLQA-PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
TIPP PH S P L LAL+ Q + P A + ASL
Sbjct: 1354 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHA----ERMASL 1409
Query: 442 TSPSRPASTPPDSPP-------LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
TS + P + + L L PL + V PL PLT P A
Sbjct: 1410 TSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFP 1469
Query: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
+ PL L PP E + P TP +LP PPP+ A
Sbjct: 1470 YPPGTLPNPL--LGQPPHEHEMLRHPV--------FGTPYPRDLPGAIPPPMSAA 1514
Score = 43.9 bits (102), Expect = 9e-04
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 859
PS P+ ++ SA M P QAP V AP +PP +P L P
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 762
Query: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919
TPGP S + A+ P P S++P+ + H+ + P+
Sbjct: 763 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 809
Query: 920 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 974
+ PPP HP+ P PPL G P AP PP G G
Sbjct: 810 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 852
Query: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034
GP S P PGP P G P QA G+ PLG A+
Sbjct: 853 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 892
Query: 1035 VQHLLSRTLLLAAAEGA 1051
H +L L A++ A
Sbjct: 893 YPH---TSLQLPASQSA 906
Score = 40.8 bits (94), Expect = 0.007
Identities = 131/592 (22%), Positives = 193/592 (32%), Gaps = 110/592 (18%)
Query: 70 IPESAPR-AGPTRSAG-TSSRN----PASRPPASGRGERAP-------PAKNTSPGPVSS 116
+P+S P + P + G T S+N PAS PP +G + AP P P P++
Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP-TGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSGPTPGTPSPA 175
P S +T P G T A P S +A G + P+
Sbjct: 1050 PTCPSTSTPPA-----------------GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQ 1092
Query: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS----EHSTTEPSPAARR----R 227
+ + E P P P + PT S +S S +H + AR
Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 1152
Query: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
P AG L + ++ + AR + K K + R +
Sbjct: 1153 PLAGSKLAKKREEAIEKAKREAEQKARE------------EREREKEKEKERERERERER 1200
Query: 288 PRKDAAPALGPLSSSPLATPSPSGT-KARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
+ AA A L+ P SG RP + P P T+ PP P
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRP------SFEPPPTTIAAVPPYIGP------ 1248
Query: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
P+L+TL A P + +P + P + P + P L
Sbjct: 1249 ---DTPALRTLSE-------YARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPT 1298
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPR-QTQASLTSPSRPASTPPDSPPLQAPLSLP- 464
+ L+ + ++ M P + + P PA+ P + + L++P
Sbjct: 1299 IRERELRER-EIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPP 1357
Query: 465 -ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
A P S P ++PL LA PQ + P + LA +
Sbjct: 1358 TAGPHPFASFHPGLNPLER----------ERLALAGPQ------LRPEMSYPDRLAAERI 1401
Query: 524 QTPP-ASLTTPPLENLPSLAPPPLQTASAPLTTP-HLET----------PPCPAPCPLQA 571
ASLT+ PL L P + + + HL P P PL A
Sbjct: 1402 HAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTA 1461
Query: 572 PP--SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
P + PP P+ + PP L P G P P P A PPP +
Sbjct: 1462 GPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVF-GTPYPRDLPGAIPPPMS 1512
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 154 bits (388), Expect = 6e-37
Identities = 234/909 (25%), Positives = 331/909 (36%), Gaps = 158/909 (17%)
Query: 165 SGPTPGTPSPAMARRSRA------AGT----EVGLPRPAPSARPRPPTEGPRKSVSSASE 214
S P+ SPA + S A +GT E G A RP PP G + S A+
Sbjct: 530 SAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATR 589
Query: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
+P+ R+RP + GGL+ P + +++P G + T P P++ +
Sbjct: 590 FLPMDPATFRRKRPESVGGLEPPGP-------SVIAAPPSGGGNILQTLVLP--PNKEEQ 640
Query: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK--ARPVPPPDNAATPLPATLP 332
+G A P P APA +PL+ P+ + RPV ++TP+P
Sbjct: 641 EGGGARVPSAPAPSLAYGAPA------APLSRPAATMVTNVVRPV-----SSTPVPIASK 689
Query: 333 PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
P P A SP+ +T + P +P ++ + T P P
Sbjct: 690 PFPTSGR----AEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP---AP 742
Query: 393 HSLTSPSL----QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448
H + P L +AP + L L T G+P A F+ + S +
Sbjct: 743 HLVAGPLLGTVGKAPATVTNL--LVGTPGYGAPAPPAVQ-FIAQGAPGGGTTAGSGAGAG 799
Query: 449 STPPDSPPL---------------QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
S P PL Q LP P Q ++PA +P P
Sbjct: 800 SGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQ-QLQVAPAPAPAPGTKAAAP----- 853
Query: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS--- 550
+ +P + + P T + + TP P L+++PS PP Q+ S
Sbjct: 854 --SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGI----PILQSVPSAPPPKAQSVSPVQ 907
Query: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
AP + P PL AP + P + +PP S P+Q PP
Sbjct: 908 APPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPP-------FSVPVQNGAQPP 960
Query: 611 LSPLA-TPPPQAPPXLALPPLQAPPSP-PASPPLSPLATPSPQAPNALAV--HLLQAPFS 666
+ TP P + P +PPL P P S P L S + + H L S
Sbjct: 961 SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS 1020
Query: 667 PPPSPP-VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPP 724
P S + P +S + ++ PS P+ P L +P +P + S P P
Sbjct: 1021 PASSQAGTVTSYGPTSSVALGFTSLGPSG--PAFVQPLLSAGQAPLLAPGQVGVSPVPSP 1078
Query: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS---PL 781
Q PP AAP V + + P S+ P A P Q PPS ++ S P
Sbjct: 1079 QLPPACAAPGGPVITAFYSGSPAPTSSAP--------LAQPSQAPPSLVYTVATSTTPPA 1130
Query: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
A P+ PPA AT A P+P + FP S + SL P P+AP + A +
Sbjct: 1131 ATILPKGPPAPAT----ATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
Query: 842 VP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897
+P + + APR+P PGP + P L P PP PP + T +
Sbjct: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTA--- 1243
Query: 898 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
SS P E R GPE A+ P ++ W R P L RG P
Sbjct: 1244 --RSSPPLPPPAEERTSAKGPETMASKFPSSSSD--------W-RVPGQGLENRGEP--- 1289
Query: 958 LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKA---------AAGA 1008
P PP S PAP A+ PG S +S G+A AAG
Sbjct: 1290 -PTPP--------------------SPAPAP-AVAPGGSSESSSGRAAGDTPERKEAAGT 1327
Query: 1009 GAGASSRSP 1017
G R P
Sbjct: 1328 GKKVKVRPP 1336
Score = 145 bits (366), Expect = 2e-34
Identities = 210/831 (25%), Positives = 290/831 (34%), Gaps = 111/831 (13%)
Query: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
RPP P PP P P G A + + AT + +G S
Sbjct: 507 RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
Query: 88 RNPASRPPASGRGERAPPAKNTSPGPVSS-------PGRASGTTRPGPLGQKGLRISAEE 140
RPP G G A P+K T P+ P G PGP + A
Sbjct: 567 TAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAP 620
Query: 141 TVARGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-- 190
G + P + G R S P P G P+ ++R + T V P
Sbjct: 621 PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVS 680
Query: 191 -RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P P A PT G ++ + + + TE +R + G+ S S++AT
Sbjct: 681 STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP 740
Query: 250 SSPARSGPSARGTPRAPAHPSQ----------PKPKGLQALR---PPQVTPPRKDAAPAL 296
+ +GP +APA + P P +Q + P T A
Sbjct: 741 APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
Query: 297 GPLSSSPLATPSPSGT-KARPVPPPDNAATPLPATLP--PSPPLATPLPLAPPSPSAPPS 353
GP PL P KA + LP L P+P A A PS AP +
Sbjct: 801 GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTT 860
Query: 354 LQTLPSPP----------ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
PP AT P+ P + + P PP Q++ P+Q P S Q
Sbjct: 861 SIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPP--GGSAQLL 918
Query: 404 PS----PLALSSLQATTS-LGSPTLQATHSF----------------LTMSPRQTQASLT 442
P PLA S+ G P + F LT P T + L
Sbjct: 919 PGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLV 978
Query: 443 SPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
P PA+ P P S P + L P T ++ S L + A S + +
Sbjct: 979 PPLSPATLPGPTSQPQKVLL------PSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032
Query: 502 APLSSLIMPPLETQSSLAP--PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE 559
P SS+ + +SL P P+ P S PL LAP Q +P+ +P L
Sbjct: 1033 GPTSSVALG----FTSLGPSGPAFVQPLLSAGQAPL-----LAPG--QVGVSPVPSPQL- 1080
Query: 560 TPPCPAPCPLQAPPSPLTTP-----PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
PP A AP P+ T P T S+ P QAPP+L +PP + +
Sbjct: 1081 -PPACA-----APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST-TPPAATI 1133
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
P AP P PS A L P Q P+ A ++A + P +
Sbjct: 1134 LPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFE 1193
Query: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
A S P P P+ L+ P+PPA PP+ + TP ++ PPL PP
Sbjct: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPL-PPP 1252
Query: 735 LQVPPSPPASPPMS---PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782
+ S M+ PS++ RVP PP+PP+ P +A
Sbjct: 1253 AEERTSAKGPETMASKFPSSSSDWRVPG-QGLENRGEPPTPPSPAPAPAVA 1302
Score = 109 bits (273), Expect = 1e-23
Identities = 239/993 (24%), Positives = 348/993 (35%), Gaps = 132/993 (13%)
Query: 81 RSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140
R +S P S A G K T +S G A+ PG + + L ++A+
Sbjct: 274 RKKSSSEAKPTSLGLAGGH-------KETRERSMSETGTAAA---PG-VSSELLSVAAQT 322
Query: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG------------ 188
++ T+AP S S GA R + PG+ P S + G
Sbjct: 323 LLSSD--TKAPGSS--SCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQ 378
Query: 189 -LPRPAPSARPRPPTE----GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
+ PA + P+P T+ GP + + T P R S QR AS ++
Sbjct: 379 MVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRS---QRAASEDMT 435
Query: 244 SSATPLSSPARSGPS------------------ARGTPRAPAHPSQPKPKGLQALRPPQV 285
S + G R T S P+G +
Sbjct: 436 SDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVF 495
Query: 286 TPP-RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344
+P R PL P P P + +++ PA+ S AT L
Sbjct: 496 SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPAS--SSASAATSFSLG 553
Query: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTP--PMQAPPSLQTIPPIQVPHSLTSPSLQA 402
+ A S Q + P PP PP P P +A L P S
Sbjct: 554 SGTFKAQESGQGSTAGPLRPP---PPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLE 610
Query: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
PP P S + A S G LQ L + P + + +R S P S AP +
Sbjct: 611 PPGP---SVIAAPPSGGGNILQT----LVLPPNKEEQE-GGGARVPSAPAPSLAYGAPAA 662
Query: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522
P S P T ++ V P+SS T P+ + S +A + E + P
Sbjct: 663 -PLSRPAATMVTNVVRPVSS--TPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPG 719
Query: 523 LQTPPASLTTPPLENLPSLAPPPLQTAS--------APLTTPHL--ETPPCPAPCP---- 568
SL ++ + +P P A AP T +L TP AP P
Sbjct: 720 GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
Query: 569 --LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
Q P TT + + P P + P G + ++ + P P L
Sbjct: 780 FIAQGAPGGGTTAGSGAGAG-SGPNGPVPLGILQPGALG-KAGGITQVQYILPTLPQQLQ 837
Query: 627 LPPLQAP-PSPPASPPLSPLATPSPQ---APNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682
+ P AP P A+ P P T S + P + A +P P P+ S P++
Sbjct: 838 VAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQ--SVPSA 895
Query: 683 PPVSPSATPPSQAPPSLAAPPLQVPPS---PPASPPMSPSATPPPQAPPPLAAPPLQVPP 739
PP + P QAPP + L +P P A+P MS Q P PL +PP VP
Sbjct: 896 PPPKAQSVSPVQAPPPGGSAQL-LPGKVLVPLAAPSMSVRGGGAGQ-PLPLVSPPFSVPV 953
Query: 740 SPPASPPMSP-SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA------L 792
A PP TP P ++ P VPP PA+LP P ++P P+ +
Sbjct: 954 QNGAQPPSKIIQLTPVP-----VSTPSGLVPPLSPATLP-GPTSQPQKVLLPSSTRITYV 1007
Query: 793 ATPPLQALP---SPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 848
+ ALP SP +S G + P++S+ + + P + P PLL +P
Sbjct: 1008 QSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGP--SGPAFVQPLLSAGQAPLL 1065
Query: 849 SPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSSSAT 905
+P P+P P + G + A G P P S +P + S P ++ + +
Sbjct: 1066 APGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATS 1125
Query: 906 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965
+TP GP A A+P P + + + + P A R +P AP A
Sbjct: 1126 TTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIA 1185
Query: 966 PGSADGLCTIYETEGPESATPAPG---ALDPGP 995
+ E S P P L+PGP
Sbjct: 1186 S------IPVGSFEAGASGRPGPAPRQPLEPGP 1212
Score = 79.0 bits (193), Expect = 2e-14
Identities = 158/670 (23%), Positives = 231/670 (34%), Gaps = 96/670 (14%)
Query: 16 TPAARAPGLLTPRPPGSPRPPPPVT-PAALRVL------GAAGAVGRKPLAERAGGIGG- 67
TP+ P L PG P V P++ R+ G A +G P + +AG +
Sbjct: 973 TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032
Query: 68 ---ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE---------RAPPAKNTSPGPVS 115
+++ GP+ A A + P G+ + PPA GPV
Sbjct: 1033 GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVI 1092
Query: 116 SP--GRASGTTRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
+ + T PL Q S TVA +T P + L G P TP
Sbjct: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVAT--STTPPAATILPKGP----PAPATATP 1146
Query: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
+P S AG+ + AP A+ RP + P+K ++ + A RP
Sbjct: 1147 APTSPFPSATAGS-MTYSLVAPKAQ-RPSPKAPQKVKAAIASIPVGSFEAGASGRPG--- 1201
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
PA R P+ P G P PA P P+ A P + PP ++
Sbjct: 1202 ----PAPRQPLEPG-PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEER 1256
Query: 293 APALGP--------LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344
A GP SSS P G + R PP + P PA P ++ A
Sbjct: 1257 TSAKGPETMASKFPSSSSDWRVPG-QGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAA 1315
Query: 345 PPSPSAPPSLQT-----LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399
+P + T + PP + + + +P + L SP+
Sbjct: 1316 GDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPT 1375
Query: 400 LQA-PPSPLAL-----SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
LQ+ SP A+ + +T L S T M R + +S P+ P S +
Sbjct: 1376 LQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSS--EPNTPKSAKCE 1433
Query: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSS-PLTIHPLQAL------------SSLASHSP 500
+ + + L P SS T+ +AL S+ A+ +
Sbjct: 1434 GDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAF 1493
Query: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTT--PPLENLPSLAPPPLQTASAPLTTPHL 558
QA + + + Q + + A+ T PP P PPP TA+AP T
Sbjct: 1494 QARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPT--- 1550
Query: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL--SPLAT 616
PSP P P +PSS + APP L PP G P +P +
Sbjct: 1551 --------------PSPAGGPDPTSPSSDSGTAQAAPP-LPPPPESGPGQPGWEGAPQPS 1595
Query: 617 PPPQAPPXLA 626
PPP P A
Sbjct: 1596 PPPPGPSTAA 1605
Score = 70.5 bits (171), Expect = 9e-12
Identities = 105/372 (28%), Positives = 132/372 (35%), Gaps = 48/372 (12%)
Query: 714 PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
PP+ P PP PP PS AS P S SA+ L + + S
Sbjct: 508 PPLDPEPPGPPD-PPVAFGKGYGSAPSSSASSPASSSASAATSFS--LGSGTFKAQESGQ 564
Query: 774 ASLPMSPLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
S PL PPP A PA + + LP PA+F + P S P P AP
Sbjct: 565 GSTA-GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIA---AP 620
Query: 833 PVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890
P +LQ PP + R P P P +LA G P P P++
Sbjct: 621 PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP-----------SLAYGAPAAPLSRPAA 669
Query: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA-PPLA 949
T+ + +STP + P G A + P D A SR P PL
Sbjct: 670 TM----VTNVVRPVSSTPVPIASKPF-PTSGRAEASPNDTAGARTEMGTGSRVPGGSPLG 724
Query: 950 F------RGAPGAPLPWPP-ATGP-----GSADGLCTIYETEGPESATPAPGALDPGPSP 997
+ + A P P GP G A T P PAP A+ +
Sbjct: 725 VSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ-FIAQ 783
Query: 998 GTSGGKAAAGAGAGASSRSPKQARLGELPLGAL-------QASVVQHLLSRTLLLAAAEG 1050
G GG AG+GAGA S LG L GAL Q + L + L +A A
Sbjct: 784 GAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPA 843
Query: 1051 AAGGS-GGGPGG 1061
A G+ P G
Sbjct: 844 PAPGTKAAAPSG 855
Score = 54.3 bits (129), Expect = 6e-07
Identities = 102/420 (24%), Positives = 140/420 (33%), Gaps = 76/420 (18%)
Query: 9 KAGAAART-PAARAPGLLTPRP-----------PGSPRPP-PPVTPAALRVLGAAGAVGR 55
+AGA+ R PA R P L P P G P PP PP P +
Sbjct: 1193 EAGASGRPGPAPRQP--LEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLP 1250
Query: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
P ER G T+ P S+ + R P RGE P + +P P
Sbjct: 1251 PPAEERTSAKGPETMASKFP------SSSSDWRVPGQG--LENRGE-PPTPPSPAPAPAV 1301
Query: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG--------- 166
+PG +S ++ G R A T + K P + + R S
Sbjct: 1302 APGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAE 1361
Query: 167 -----PTPGTPSPAMARRSRAAGTEVGLPRPAPS------ARPRPPTEGPRKSVSSASEH 215
P PSP + + + +G R + P PT P++ + S
Sbjct: 1362 LPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTS-PKRKMRRRSSC 1420
Query: 216 STTEPSPAARRRPSAGGGLQRPASRS------LSSSATPLSSPARS-------------- 255
S+ +P + + R + + L P SS R+
Sbjct: 1421 SSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQD 1480
Query: 256 ---GPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALG--PLSSSPLATPSP 309
PSA+ T A + P K L+ +V AA P + +PL P P
Sbjct: 1481 HGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPP 1540
Query: 310 SGTKARPVPPPDNAATPLPATLPPS----PPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365
+GT A P P P A P P T P S A PLP P S P + P P PP
Sbjct: 1541 TGTAAAPAPTPSPAGGPDP-TSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPP 1599
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/87 (39%), Positives = 39/87 (44%), Gaps = 12/87 (13%)
Query: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLAAPPL 704
ATP+ Q P A +AP PP A +P SP P T PS + + AAPPL
Sbjct: 1522 ATPTEQPPGA------EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPL 1575
Query: 705 QVPPSPPASPPMSPS--ATPPPQAPPP 729
P PP S P P P P PPP
Sbjct: 1576 ---PPPPESGPGQPGWEGAPQPSPPPP 1599
Score = 47.0 bits (110), Expect = 1e-04
Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 21/108 (19%)
Query: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821
AA P + PP A LP+ PPP A P PSP +P S S +
Sbjct: 1521 AATPTEQPPGAEAPLPV-----PPPTGTAAAPAP----TPSPAGGPDPTSPSSDSGTAQA 1571
Query: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869
+P PPP++ P P + P P PP PGP T+ +G
Sbjct: 1572 APPLPPPPESGP--GQPGWEGAPQP----------SPPPPGPSTAATG 1607
Score = 44.3 bits (103), Expect = 7e-04
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 21/110 (19%)
Query: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
+ +ATP Q PP AP +P PP +P+ TP P P P+ P+S
Sbjct: 1518 IMQAATPTEQ-PPGAEAP---LPVPPPTGTAAAPAPTPSPAGGP---------DPTSPSS 1564
Query: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
+ A PP +PP PP P P +P PPP P AT
Sbjct: 1565 DSGTAQAAPP--LPP----PPESGPGQP--GWEGAPQPSPPPPGPSTAAT 1606
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 31/113 (27%)
Query: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP--GPD-TSVSGPRLTLALAPGPP 881
A P + PP APL P PP + T AP P+P GPD TS S T AP P
Sbjct: 1521 AATPTEQPPGAEAPL----PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLP 1576
Query: 882 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934
PPP P G++ P+ + PPP AA
Sbjct: 1577 PPPESGPGQP---------------------GWEGAPQ---PSPPPPGPSTAA 1605
Score = 40.4 bits (93), Expect = 0.010
Identities = 43/151 (28%), Positives = 56/151 (37%), Gaps = 20/151 (13%)
Query: 653 PNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709
P ++AV H L PF P P S P P A+ S+ P AA + PP
Sbjct: 29 PRSVAVFPWHSL-VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPG 87
Query: 710 PPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS-PSATPPPRVPPL------- 760
S P P P++P P PL V S PP + A+ PP P L
Sbjct: 88 GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESD 147
Query: 761 -------LAAPPLQVPPSPPASLPMSPLAKP 784
+ +P +Q+P P S A P
Sbjct: 148 HDDAFLSIMSPEIQLPLPPGKRRTQSLSALP 178
Score = 38.9 bits (89), Expect = 0.028
Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 584 PSSIATPP-----PQAPPALASPPLQGLPS--PPLSPLATPPPQAPPXLALPPLQAPP-- 634
P S+A P P P+ P +Q + P P+A+ + P A + PP
Sbjct: 29 PRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGG 88
Query: 635 SPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSA 689
+ A P P AT P P P+ L V +++ PPP+ +A PP P + S +
Sbjct: 89 TGSADPERPPGATCPESPGPGPPHPLGV--VESGKGPPPTTEEEAS-GPPGEPRLDSETE 145
Query: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
+ A S+ +P +Q+P P S SA P
Sbjct: 146 SDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALP 178
Score = 38.5 bits (88), Expect = 0.036
Identities = 29/101 (28%), Positives = 35/101 (34%), Gaps = 21/101 (20%)
Query: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
A P + PP P P PP +P TPSP P P+ P
Sbjct: 1521 AATPTEQPPGAEAP---LPVPPPTGTAAAPAPTPSPAG-------------GPDPTSPSS 1564
Query: 675 APFSPPASPPVSPSATPPSQAP--PSLAAPPLQVPPSPPAS 713
+ A+PP+ P PP P P P PP P S
Sbjct: 1565 DSGTAQAAPPLPP---PPESGPGQPGWEGAPQPSPPPPGPS 1602
Score = 38.5 bits (88), Expect = 0.036
Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 12/95 (12%)
Query: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 723
P PP P PP +P+ TP P P+ P+S + A PP
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPD---------PTSPSSDSGTAQAAPP 1574
Query: 724 PQAPPPLAAP--PLQVPPSPPASPPMSPSATPPPR 756
PPP + P P P+ PP PS R
Sbjct: 1575 -LPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
Score = 36.6 bits (83), Expect = 0.14
Identities = 36/128 (28%), Positives = 47/128 (36%), Gaps = 26/128 (20%)
Query: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT--- 325
PSQP P P + PA P++S+ P+ S A PP +
Sbjct: 46 PSQPDPS----------VQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE 95
Query: 326 -PLPATLPPSPPLATPLPLA--------PPS----PSAPPSLQTLPSPPATPPSQAPPSM 372
P AT P SP P PL PP+ S PP L S + A S+
Sbjct: 96 RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSI 155
Query: 373 TTPPMQAP 380
+P +Q P
Sbjct: 156 MSPEIQLP 163
Score = 31.6 bits (70), Expect = 4.4
Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 8/138 (5%)
Query: 496 ASHSPQAPLSSLIMPPLE--TQSSLAPPSLQTPPASLTTP---PLENLPSLAPPPLQT-A 549
++H P P SS L +++ P S+ P P P + PS+ P Q A
Sbjct: 3 SAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPA 62
Query: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP--PPQAPPALASPPLQGLP 607
S P+ + + P A + PP + PE P P P PP G
Sbjct: 63 SHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKG 122
Query: 608 SPPLSPLATPPPQAPPXL 625
PP + P P L
Sbjct: 123 PPPTTEEEASGPPGEPRL 140
Score = 30.8 bits (68), Expect = 7.5
Identities = 21/92 (22%), Positives = 27/92 (29%), Gaps = 7/92 (7%)
Query: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
P +PP + PP T+ P +P A G P G T
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSG-------TAQAAPPLP 1576
Query: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
P S P+P P P+ A R
Sbjct: 1577 PPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
Score = 30.4 bits (67), Expect = 9.9
Identities = 39/149 (26%), Positives = 51/149 (34%), Gaps = 24/149 (16%)
Query: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-PGPDTS 866
P AP P S+ P +A + P+ PA A RPP G
Sbjct: 42 PFLAPSQPDPSVQ-------PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADP 94
Query: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 926
P T +PGP PP + GP +T EE SGP G P
Sbjct: 95 ERPPGATCPESPGPGPPHPLGVVESGKGP--------PPTTEEEA----SGPPG----EP 138
Query: 927 PPDAELAACHPAAWSRGPAPPLAFRGAPG 955
D+E + H A+ +P + PG
Sbjct: 139 RLDSETESDHDDAFLSIMSPEIQLPLPPG 167
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 152 bits (385), Expect = 1e-36
Identities = 176/589 (29%), Positives = 221/589 (37%), Gaps = 94/589 (15%)
Query: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---SPP 456
L P P + +SL + ++ S Q + + Q L S + A +P SPP
Sbjct: 598 LLPPTLPTSATSLASDSTFDSG--QGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPP 655
Query: 457 LQAPLSLPAS-PPLQTSLSPAVSPLSSPLTIHPLQALS-SLASHSPQAPLS-SLIMPPLE 513
+ LP S P L P +P P+ P A SL H P +S + ++PP
Sbjct: 656 VSEGPVLPQSLPSLGAYQQPTAAP-GLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPS 714
Query: 514 TQSSL-----APPSLQTPPASLTTP-----------PLENLPSLAPPPLQTAS---APLT 554
T APP Q PP + TP PL+ +P PP L AS AP
Sbjct: 715 TPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774
Query: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLSP 613
L+ P QAP PL PP+ P P P PP + GLP P P
Sbjct: 775 LKPLQMP--------QAPLQPLAQVPPQMP-----PIPVVPPITPLAGIDGLPPALPDLP 821
Query: 614 LATPPPQAPPXLALP----PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP- 668
AT PP PP P P A P PPASP L A P P A P + P
Sbjct: 822 TATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGA--------PLAMPC 873
Query: 669 ----PSPPVQAPFSPPASPPV------SPSATPPSQAPPSLAAP---PLQVPPSP----- 710
P+ P P A P V S A P Q A P P VPPSP
Sbjct: 874 RTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQ 933
Query: 711 --PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
A+PP P+ P P PP PP P P PP P+ P P +PP PP V
Sbjct: 934 NMRATPP-QPALPPQPTLPPQPVLPPQPTLPPQPVLPP-QPTRPPQPVLPPQPMLPPQPV 991
Query: 769 -PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLPMSPLAT 826
PP P + PL P+ ATP Q L PA + A P+ +P + + +
Sbjct: 992 LPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051
Query: 827 PP-------------PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPRL 872
PP PQ P LA V P + TL P PP P GP + P +
Sbjct: 1052 PPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTV 1111
Query: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
L + P S+ L + S ++ +EL G GG
Sbjct: 1112 QLTVEPVQEEQASQDKPPGLP-QSCESYGGSDVTSGKELSDSCEGAFGG 1159
Score = 137 bits (346), Expect = 4e-32
Identities = 172/644 (26%), Positives = 225/644 (34%), Gaps = 100/644 (15%)
Query: 155 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR------PPTEGPRKS 208
AL ++D P P + + G P P P PPT P +
Sbjct: 549 ALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTL-PTSA 607
Query: 209 VSSASE-----------HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
S AS+ +S ++ S + S PA S + +S P
Sbjct: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLP 667
Query: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317
S + A P P PP + D A + P+ P +TP P+G +P
Sbjct: 668 SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPP-STPMPTGP-GQPA 725
Query: 318 PPPDNAATPLPATLP-PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
PP P P P P P + P P+ P LQ P PP PP AP S P
Sbjct: 726 PPGQQ---PPPLAQPTPLPQVLAPQPVVP--------LQ--PVPPHLPPYLAPASQVGAP 772
Query: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS--------PTLQATHS 428
Q + P+Q+P + P Q PP + + T L P L
Sbjct: 773 AQ-------LKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATV 825
Query: 429 FLTMSPRQTQASLTSPSRPASTPPDSP--PLQA-----PLSLPASPPLQTSLSPAVSPLS 481
P+ ++ PS A PP SP PLQA P P + P +T + A P +
Sbjct: 826 PPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA--PAT 883
Query: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541
PL +++L+ HS A L P PA+ P +
Sbjct: 884 IPLLAVAPPGVAALSIHSAVAQL----------------PGQPVYPAA--------FPQM 919
Query: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALAS 600
AP + + TPP PA PP P P P P PP P PP
Sbjct: 920 APTDVPPSPHHTVQNMRATPPQPA-----LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTR 974
Query: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ------APN 654
PP LP P+ P P P PP ALP P P +P ATP Q AP
Sbjct: 975 PPQPVLPPQPMLP---PQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPY 1031
Query: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
A+ V Q P P P V +P P P +P P Q P SLA V P +
Sbjct: 1032 AVDV-AAQVPTVPVPPAAVLSPPLPEVLLPAAPELLP--QFPSSLATVSASVQSVPTQTA 1088
Query: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
+ P A PP P +A+P V + S PP +P
Sbjct: 1089 TLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
Score = 85.1 bits (209), Expect = 3e-16
Identities = 142/551 (25%), Positives = 191/551 (34%), Gaps = 66/551 (11%)
Query: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
D++ + + AA +P PP S P V P +L LGA ++P A
Sbjct: 627 DSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP---VLPQSLPSLGAY----QQPTAAP 679
Query: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPAS----GRGERAPPAKNTSPGPVSSP 117
+G P P S P PP++ G G+ APP + P P++ P
Sbjct: 680 GLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQ--PPPLAQP 737
Query: 118 GRASGTTRPGPLGQ-KGLRISAEETVARGKATEAPKR----SALSAGARRDTSGPTPGTP 172
P P+ + + +A AP + A + P P
Sbjct: 738 TPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797
Query: 173 SPAMARRSRAAGTEVGLPRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
P + + AG + GLP P PP P+ + S P P
Sbjct: 798 IPVVPPITPLAGID-GLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLP-------- 848
Query: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
PAS +L A L P P A P P+ P L A+ PP V
Sbjct: 849 ------PASPALPLQAVKLPHPP-GAPLAM--PCRTIVPNAPATIPLLAVAPPGVAALSI 899
Query: 291 DAAPALGPLSSS-PLATPSPSGTKARPVPP---PDNAATPLPATLPPSPPLATPLPLAPP 346
+A A P P A P + T P P + ATP LPP P L P P+ PP
Sbjct: 900 HSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP-PQPVLPP 958
Query: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
P+ PP P P P PP PP P L P + V P L +P
Sbjct: 959 QPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQ---PVLPPQPALPVRPEPLQPHLPEQAAP 1015
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---SPPLQAPLSL 463
A Q LG P +P + P+ P PP SPPL L L
Sbjct: 1016 AATPGSQIL--LGHP-----------APYAVDVAAQVPTVP--VPPAAVLSPPLPEVL-L 1059
Query: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
PA+P L +++ +S+ + P Q + L +P P I P T P +
Sbjct: 1060 PAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEP-V 1118
Query: 524 QTPPASLTTPP 534
Q AS PP
Sbjct: 1119 QEEQASQDKPP 1129
Score = 67.4 bits (163), Expect = 7e-11
Identities = 142/561 (25%), Positives = 181/561 (32%), Gaps = 118/561 (21%)
Query: 398 PSLQAPPS--PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
P+ +AP S PL LSSL S S + S L S + P S PP +P
Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-SNPPGAP 1380
Query: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515
P APL+ P+SPP+ +P +S + P +S A P P + LET
Sbjct: 1381 P--APLA-PSSPPVTALPQDGAAPATSTMP-EPASGTASQAG-GPGTPQG--LTSELETS 1433
Query: 516 SSLAPPSLQTPPASLTTPPLE-NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574
LA +T A L PL L P P ++ + P PP PAP PS
Sbjct: 1434 QPLA----ETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPP-PAP-----EPS 1483
Query: 575 PLT-TPPPETPSSIATPPPQAPPALASPPL--QGLPSPPLSPLATPPPQAPPXLALPPLQ 631
P + TP P ++ P P P A+ + L LPSPPL P P PP +
Sbjct: 1484 PHSGTPQP----ALGQPAPLLPAAVGAVSLATSQLPSPPLGPTV---PPQPPSALESDGE 1536
Query: 632 APP-------------SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP----SPPVQ 674
PP L P+ A V + F+ P P +
Sbjct: 1537 GPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSE 1596
Query: 675 APFSPPASPPVSPSAT------PPSQAPPSLAAPPLQVPPSPPASPPMSPSATP------ 722
A PPV A P S AP S M+ ++P
Sbjct: 1597 VCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGY 1656
Query: 723 ----------------PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP----------R 756
PQ P P P SA PPP
Sbjct: 1657 DRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQAS 1716
Query: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKP-------PPQAPPALATPPLQALPSPPASFPG 809
P L A L P P +S AK Q LA+P +PP +
Sbjct: 1717 HPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLD 1776
Query: 810 QAPFSPSASLPMSPLATP-------------------PPQAPPVLAAPLLQVPPS----- 845
+AP SP L + T P PPV L V S
Sbjct: 1777 EAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDF 1836
Query: 846 -PPASPTLQAPRRPPTPGPDT 865
A+ LQ P R + GP+T
Sbjct: 1837 VKKATAFLQRPSRAGSLGPET 1857
Score = 58.5 bits (140), Expect = 3e-08
Identities = 76/276 (27%), Positives = 102/276 (36%), Gaps = 46/276 (16%)
Query: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA--A 732
AP +P +SPP+ S+ PP + S P +S P A L A
Sbjct: 1323 APEAPESSPPLPLSSLPPEASQDSA-----------PYKDQLSSKEQPSFLASQQLLSQA 1371
Query: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA- 791
P P +PPA P++PS+ P +P AAP P P + PQ +
Sbjct: 1372 GPSNPPGAPPA--PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSE 1429
Query: 792 --LATPPLQALPSPPASFP---GQAPFSPS--------ASLPMSPLATPPPQAPPVLAAP 838
+ P + +P A P G AP +P+ AS P PL P P+ P P
Sbjct: 1430 LETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTP 1489
Query: 839 ---LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
L Q P PA+ + P P GP + PP PPS S P
Sbjct: 1490 QPALGQPAPLLPAAVGAVSLATSQLPSPPL---GPTV-------PPQPPSALESDGEGPP 1539
Query: 896 DLAGH-SSSATSTPEELRG---YDSGPEGGAAASPP 927
G S+ S E+LR + P A+A P
Sbjct: 1540 PRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTP 1575
Score = 55.8 bits (133), Expect = 2e-07
Identities = 134/605 (22%), Positives = 191/605 (31%), Gaps = 118/605 (19%)
Query: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRPSAGGGLQRPASRSLSSSA 246
PAP A P P +SS ++ + +P +++ +PS AS+ L S A
Sbjct: 1322 PAPEA----PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF------LASQQLLSQA 1371
Query: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
P + P G P AP PS P P P+ AAPA + T
Sbjct: 1372 GPSNPP--------GAPPAPLAPSSP----------PVTALPQDGAAPATSTMPEPASGT 1413
Query: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
S +G P T P PLA + +P P P +T +
Sbjct: 1414 ASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTP-----APEAASTRDA 1468
Query: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
AP PP P PHS T P+PL +++ A + S
Sbjct: 1469 SAPREPLPPPAPEPS----------PHSGTPQPALGQPAPLLPAAVGAVSLATS------ 1512
Query: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
L SP + PP PP PP + + L L
Sbjct: 1513 -------------QLPSPPLGPTVPP-QPPSALESDGEGPPPRVGFVDSTIKSLDEKLRT 1558
Query: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Q +S S P+ + +L P P + + L +L P P
Sbjct: 1559 LLYQEHVPTSSASAGTPVE-----VGDRDFTLEPLRGDQPRSEVCGGDL----ALPPVPK 1609
Query: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606
+ S + P P ++ +P E +S + +P ++ G
Sbjct: 1610 EAVSGRVQLPQ--------PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGR 1661
Query: 607 PSPPLSPLATPPPQAPPXLALPPLQAPP--------SPPASPPLSPLATPSPQA--PNAL 656
S + PQ P P P A PP S + T QA P L
Sbjct: 1662 QVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTL 1721
Query: 657 AVHLLQAPFSPPPSPPVQAP------FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
L +P P V +P FS ++ A+P S +APP
Sbjct: 1722 GARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSL---RYSAPPDVYLDEA 1778
Query: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
P+SP + + A ++V P S S S PR A PP+Q
Sbjct: 1779 PSSPDVKLAVRRAQ------TASSIEVGVGEPVS---SDSGDEGPR-----ARPPVQKQA 1824
Query: 771 SPPAS 775
S P S
Sbjct: 1825 SLPVS 1829
Score = 53.5 bits (127), Expect = 1e-06
Identities = 121/506 (23%), Positives = 168/506 (33%), Gaps = 112/506 (22%)
Query: 76 RAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
+AGP+ G + P+S P + + A PA +T P P S +G GP +G
Sbjct: 1370 QAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG----GPGTPQG 1425
Query: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
L E + + EAP + G P TP+P A A+ LP PA
Sbjct: 1426 LTSELETSQPLAETHEAP------LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA 1479
Query: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
P P T P + +P+P P+A G + SL++S P SP
Sbjct: 1480 PEPSPHSGTPQP----------ALGQPAPLL---PAAVGAV------SLATSQLP--SP- 1517
Query: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT------- 306
P P P QP P L++ + PPR + L T
Sbjct: 1518 ---------PLGPTVPPQP-PSALES--DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565
Query: 307 PSPSGTKARPVPPPDNAAT--PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
P+ S + PV D T PL P S L L P A LP P
Sbjct: 1566 PTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEK 1625
Query: 365 PSQAP-----------PSMT------------------TPPMQAPPSLQTIPPIQVPHSL 395
AP SMT PS+ P V +
Sbjct: 1626 SELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPAR 1685
Query: 396 TSP-----------SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
P S + PPS + QA+ P + + R Q ++SP
Sbjct: 1686 VEPTDRDGGEAGESSAEPPPSDMGTVGGQAS----HPQTLGARALGSPRKRPEQQDVSSP 1741
Query: 445 SRPAS-----TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
++ + D L +P SL S P L A S L + Q SS+
Sbjct: 1742 AKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGV 1801
Query: 500 PQAPLSS-------LIMPPLETQSSL 518
+ P+SS PP++ Q+SL
Sbjct: 1802 GE-PVSSDSGDEGPRARPPVQKQASL 1826
Score = 50.4 bits (119), Expect = 9e-06
Identities = 70/241 (29%), Positives = 90/241 (37%), Gaps = 37/241 (15%)
Query: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
P P S P PL+ PP+A A P L S Q F S L + PP
Sbjct: 1324 PEAPESSPPLPLSSLPPEASQDSA-PYKDQLSSKE-----QPSFLASQQLLSQAGPSNPP 1377
Query: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
APP APL P SPP + Q P T SG T + A GP P +
Sbjct: 1378 GAPP---APL--APSSPPVTALPQDGAAPATSTMPEPASG---TASQAGGPGTPQGLTSE 1429
Query: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 949
S P H + P + G A +P P+A A+ A+ R P PP A
Sbjct: 1430 LETSQPLAETHEAPLAVQPLVV--------GLAPCTPAPEA--ASTRDASAPREPLPPPA 1479
Query: 950 FRGAPGAPLPWP----PATGPGSADGLCTIYETE------GPESATPAPGALD---PGPS 996
+P + P P PA +A G ++ ++ GP P AL+ GP
Sbjct: 1480 PEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539
Query: 997 P 997
P
Sbjct: 1540 P 1540
Score = 47.0 bits (110), Expect = 1e-04
Identities = 71/242 (29%), Positives = 93/242 (38%), Gaps = 47/242 (19%)
Query: 780 PLAK-PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 838
P+A+ P P+AP + +PPL PP + AP+ S P Q
Sbjct: 1317 PVAEHPAPEAPES--SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQL------- 1367
Query: 839 LLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897
L Q PS PP +P AP P +P P T++ P+ A A P P+ +S GP
Sbjct: 1368 LSQAGPSNPPGAPP--APLAPSSP-PVTAL--PQDGAAPATSTMPEPASGTASQAGGPGT 1422
Query: 898 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
+S T + L P A P LA C PA A AP P
Sbjct: 1423 PQGLTSELETSQPLAETHEAP----LAVQPLVVGLAPCTPAP----EAASTRDASAPREP 1474
Query: 958 LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGASSR 1015
LP PPA PE P+P + P P+ G AA GA + A+S+
Sbjct: 1475 LP-PPA-----------------PE---PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQ 1513
Query: 1016 SP 1017
P
Sbjct: 1514 LP 1515
Score = 43.9 bits (102), Expect = 9e-04
Identities = 100/432 (23%), Positives = 147/432 (34%), Gaps = 53/432 (12%)
Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-GGIGGAT 69
G A TPA A P P PPP P+ PL A G + AT
Sbjct: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLAT 1511
Query: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
+P GPT +PP++ ++ GP G T + L
Sbjct: 1512 SQLPSPPLGPT---------VPPQPPSA--------LESDGEGPPPRVGFVDSTIK--SL 1552
Query: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
+K + +E V A+ + + G R T P G RS G ++ L
Sbjct: 1553 DEKLRTLLYQEHVPTSSASAG---TPVEVGDRDFTLEPLRGDQP-----RSEVCGGDLAL 1604
Query: 190 ---PRPAPSARPRPPTEGPRKS----VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
P+ A S R + P KS A T S A P + G R +
Sbjct: 1605 PPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVA 1664
Query: 243 SSSATPLS---------SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
S S S PAR P+ R A ++P P + + Q + P+ A
Sbjct: 1665 SDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTV-GGQASHPQTLGA 1723
Query: 294 PALGPLSSSP----LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349
ALG P +++P+ + + V D P +L S P L AP SP
Sbjct: 1724 RALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPD 1783
Query: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL-TSPSLQAPPSPLA 408
+++ + + P + + P + PP+Q SL S S+ A
Sbjct: 1784 VKLAVRRAQTASSIEVGVGEPVSSDSGDEGP---RARPPVQKQASLPVSGSVAGDFVKKA 1840
Query: 409 LSSLQATTSLGS 420
+ LQ + GS
Sbjct: 1841 TAFLQRPSRAGS 1852
Score = 36.2 bits (82), Expect = 0.18
Identities = 35/136 (25%), Positives = 48/136 (35%), Gaps = 31/136 (22%)
Query: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
P P G G PA A P + AR GP R R+ Q +P GL+A
Sbjct: 11 PGTLMEPGRGAG---PAGM-----AEPRAKAARPGPQ-RFLRRSVVESDQEEPPGLEAAE 61
Query: 282 PPQVTPPR----------------------KDAAPALGPLSSSPLATPSPSGTKARPVPP 319
P PP+ + AAPA L + P A +P+ PV
Sbjct: 62 APGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGT 121
Query: 320 PDNAATPLPATLPPSP 335
+ P+ A + +P
Sbjct: 122 QEPGPDPIAAAVETAP 137
Score = 32.3 bits (72), Expect = 2.6
Identities = 44/166 (26%), Positives = 51/166 (30%), Gaps = 18/166 (10%)
Query: 832 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPPS 885
P L P P+ A P +A R P SV P L A APGP PP
Sbjct: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70
Query: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRG 943
L + E RG + P A + P P A A ++
Sbjct: 71 LQRRVLLL-------CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQE 123
Query: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989
P P AP P GP E EG A P PG
Sbjct: 124 PGPDPIAAAVETAP---APDGGPREEAAATVRKEDEGAAEAKPEPG 166
Score = 30.4 bits (67), Expect = 9.9
Identities = 39/155 (25%), Positives = 56/155 (36%), Gaps = 30/155 (19%)
Query: 111 PGPVSSPGRASG----------TTRPGPLGQKGLRISAEETVARG----KATEAP----- 151
PG + PGR +G RPGP Q+ LR S E+ +A EAP
Sbjct: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGP--QRFLRRSVVESDQEEPPGLEAAEAPGPQPP 68
Query: 152 ----KRSALSAGARR---DTSGPTPGTPSPA-MARRSRAAGTEVGL-PRPAPSARPRPPT 202
+R L RR + + P P+PA + + A G P P + P P
Sbjct: 69 QPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDP 128
Query: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
+ A + E + A R+ G +P
Sbjct: 129 IAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKP 163
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 152 bits (384), Expect = 2e-36
Identities = 213/807 (26%), Positives = 292/807 (36%), Gaps = 92/807 (11%)
Query: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
P GSP P P+ + R LA+ G A R G R
Sbjct: 745 PEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLR 804
Query: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE--TVARGK 146
+ G G+ P T GP +G +G KG S + + A GK
Sbjct: 805 DATVACWELGCGKVRPRVGKTHYGP------GTGPIWLDDMGCKGSEASLSDCPSGAWGK 858
Query: 147 AT-EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
+ + L+ D P T P T G+P P T P
Sbjct: 859 HNCDHEEDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPG---HTLPWRTTRRP 915
Query: 206 RKSVSSASEHSTTEPSPAARRRPSAGGG--------LQRPASRSLSSSATPLSSPARSGP 257
S SPA RR P G P+ R L+ TP + + GP
Sbjct: 916 GSS------------SPAIRRLPDTGSKDGYKLPWTWDTPSGRGLAEG-TPTAG--KLGP 960
Query: 258 S-ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-GTKAR 315
+ GT R+P P + G P + P R+ PA ++ A P+PS G A
Sbjct: 961 TLGAGTTRSPGSPPTLRVHG-DTGSPRKPWPERRPPRPA-----ATRTAPPTPSPGPSAS 1014
Query: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP---PSLQTLPSPPATPPSQA---P 369
P PP + L P L + P S P P+ +T P T P A P
Sbjct: 1015 PGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTP 1074
Query: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLGSPTLQATHS 428
S P + PS +P + P LTS PS + + L+ +S Q S +P L T
Sbjct: 1075 DSSVVPALTPEPSPTPLPTL--PKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPY 1132
Query: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
T+S +++ SPS +T PD P AP + T+L+P V+P P T HP
Sbjct: 1133 SSTVS-EYSRSPDPSPSPHPTTTPD--PTMAPDPI-------TTLNPTVTP-HFPTTPHP 1181
Query: 489 LQALS-SLASHSPQAPLSSLIMPPLET--QSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
+ +HS P + P T S++ P TP T P S P P
Sbjct: 1182 TTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHP 1241
Query: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET-PSSIATPPPQAPP-ALASPPL 603
T P T H P P P P TT P T P TP P P +P
Sbjct: 1242 TTTPH-PTTITHSTMIPDPT-----TTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHP 1295
Query: 604 QGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661
P P ++P TP P P P P P ++P ++ ++ P+ +L L
Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPT-----SLGTELS 1350
Query: 662 QAPFSPPPSPPV--QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
+P P + Q F+ PA P S S P + P+L + P + + P +
Sbjct: 1351 SPTLAPTVKPSLHPQLTFTAPA-PHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTED 1409
Query: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS 779
PP P L PP P S + +P P + P A PL PP P +L +
Sbjct: 1410 FKPPRSQSPNLTPPPTHTPHSAS-----DLTVSPDPLLSP--TAHPLDHPPLDPLTLGPT 1462
Query: 780 PLAKPPPQAPPALATPPLQALP-SPPA 805
P P P P TPP++ + PPA
Sbjct: 1463 PGQSPGPHGPCVAPTPPVRVMACEPPA 1489
Score = 145 bits (367), Expect = 2e-34
Identities = 191/685 (27%), Positives = 242/685 (35%), Gaps = 134/685 (19%)
Query: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP---- 192
++ E +A+G T L R PG+ SPA+ RR G++ G P
Sbjct: 888 TSREDLAKGTTTAGVPGHTLPWRTTR-----RPGSSSPAI-RRLPDTGSKDGYKLPWTWD 941
Query: 193 APSAR---PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ-----RPASRSLSS 244
PS R PT G A + P R G + RP + +
Sbjct: 942 TPSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATR 1001
Query: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP------------PQVTPPRKDA 292
+A P SP GPSA P PA S + L P P +PP D
Sbjct: 1002 TAPPTPSP---GPSASPGPPGPALTSDSS----RELTPHSALTSEATSDAPDTSPPTPDP 1054
Query: 293 APALGP---LSSSPLATPSPSGTKARPVPPPDNAATPLPATLP------PSPPLATPLPL 343
A P L+S A +P + P P+ + TPLP TLP PS P + L
Sbjct: 1055 ASRTNPDLILTSPDFALSTPDSSVV-PALTPEPSPTPLP-TLPKELTSDPSTP-SEVTSL 1111
Query: 344 APPSPSAPPSLQTLPSPPATP-------------PSQAPPSMTTP-PMQAPPSLQTIPPI 389
+P S P S T P TP PS +P TTP P AP + T+ P
Sbjct: 1112 SPTSEQVPES-DTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPT 1170
Query: 390 QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
PH T+P P P + THS + P T T+ +
Sbjct: 1171 VTPHFPTTPHPTTTPHPTTI----------------THSTMIPDPTTTPQPFTTITHSTM 1214
Query: 450 TP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
P P + P P + P T+ P +P HP + +HS P +
Sbjct: 1215 IPDPTTTPQPFTTMQPTTTPHSTTPHPTTTP-------HP-----TTITHSTMIPDPTTT 1262
Query: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
P T P T P TTP P TTPH T P P P
Sbjct: 1263 PQPFTTMQPTTMPHPTTTPHPTTTPH-----------------PTTTPHPTTTPHPTMTP 1305
Query: 569 -LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG-----LPSPPLSPLATPPPQAP 622
P P TTP P T TP P + P + + L L SP L+P T P
Sbjct: 1306 DPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAP--TVKPSLH 1363
Query: 623 PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682
P L P+P S P PSP AL ++ + P F PP S
Sbjct: 1364 PQLTF----TAPAPHTSTSQIPTLEPSP----ALESSPSRSSTATSMDPLSTEDFKPPRS 1415
Query: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP---- 738
SP+ TPP P +A L V P P SP P PP P L P Q P
Sbjct: 1416 Q--SPNLTPPPTHTPH-SASDLTVSPDPLLSPTAHP-LDHPPLDPLTLGPTPGQSPGPHG 1471
Query: 739 PSPPASPPMSPSATPPPRVPPLLAA 763
P +PP+ A PP + L+AA
Sbjct: 1472 PCVAPTPPVRVMACEPPALVELVAA 1496
Score = 133 bits (335), Expect = 8e-31
Identities = 156/568 (27%), Positives = 209/568 (36%), Gaps = 90/568 (15%)
Query: 347 SPSAPPSLQT---LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
SP +PP+L+ SP P + PP P + +T PP P SP P
Sbjct: 969 SPGSPPTLRVHGDTGSPRKPWPERRPPR--------PAATRTAPPTPSPGPSASPG---P 1017
Query: 404 PSP-LALSSLQATTSLGSPTLQATHSFL-TMSPRQTQASLTSPSRPASTP------PDSP 455
P P L S + T + T +AT T P AS T+P ++P PDS
Sbjct: 1018 PGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSS 1077
Query: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET- 514
+ A P+ PL T S S+P + +SL+ S Q P S P L+T
Sbjct: 1078 VVPALTPEPSPTPLPTLPKELTSDPSTPSEV------TSLSPTSEQVPESDTT-PDLDTT 1130
Query: 515 --QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572
S+++ S P+ P P++AP P+ T + P TPH T P P P
Sbjct: 1131 PYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLN-PTVTPHFPTTPHPTTTPHPTT 1189
Query: 573 -------PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
P P TTP P T + +T P P P + P TP P
Sbjct: 1190 ITHSTMIPDPTTTPQPFTTITHSTMIPD-------PTTTPQPFTTMQPTTTPHSTTPHPT 1242
Query: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
P P+ + P T +PQ + + P + P P +P
Sbjct: 1243 TTPH----PTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTP---------HPTTTP-- 1287
Query: 686 SPSATP-PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
P+ TP P+ P P P P +P P+ TP P P P + P + P +
Sbjct: 1288 HPTTTPHPTTTPHPTMTPDPTTTPYPTTTP--DPTTTPHPTTPDPSSTPVITTVSLPTSL 1345
Query: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
S T P V P L P+P S P +P +P L++ PS
Sbjct: 1346 GTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEP---------SPALESSPSRS 1396
Query: 805 ASFPGQAPFSPSASLP---MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--- 858
++ P S P SP TPPP P A+ L V P P SPT P
Sbjct: 1397 STATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASD-LTVSPDPLLSPTAHPLDHPPLD 1455
Query: 859 -----PTPGPDTSVSGPRLTLALAPGPP 881
PTPG GP +AP PP
Sbjct: 1456 PLTLGPTPGQSPGPHGP----CVAPTPP 1479
Score = 126 bits (316), Expect = 1e-28
Identities = 174/679 (25%), Positives = 233/679 (34%), Gaps = 141/679 (20%)
Query: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK-PLA-E 60
++ D AK A P P T RP S +PA R+ G K P +
Sbjct: 889 SREDLAKGTTTAGVPGHTLPWRTTRRPGSS-------SPAIRRLPDTGSKDGYKLPWTWD 941
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG----------ERAPP---AK 107
G G A +A + GPT AGT+ R+P S P G ER PP A
Sbjct: 942 TPSGRGLAEGTPTAGKLGPTLGAGTT-RSPGSPPTLRVHGDTGSPRKPWPERRPPRPAAT 1000
Query: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167
T+P P SPG ++ PGP + + E SAL++ A D
Sbjct: 1001 RTAP-PTPSPGPSASPGPPGP------------ALTSDSSRELTPHSALTSEATSDAPDT 1047
Query: 168 TPGTPSPAMARRSRAAGTEVGL--------------PRPAPSARPRPP---TEGPRKSVS 210
+P TP PA T P P+P+ P P T P
Sbjct: 1048 SPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSE 1107
Query: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP------------- 257
S T+E P + P S S P SP +
Sbjct: 1108 VTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTL 1167
Query: 258 SARGTPRAPAHP---SQPKPKGL--QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312
+ TP P P + P P + + P T P+ + P TP P T
Sbjct: 1168 NPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPF-T 1226
Query: 313 KARPVPPPDNAATPLPATLPPSPPLA----TPLPLAPPSPSAPPSLQTLPSPPATP-PSQ 367
+P P ++ TP P T P + P P P P T+P P TP P+
Sbjct: 1227 TMQPTTTP-HSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTT 1285
Query: 368 APPSMTTP-PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
P TTP P P T P P+ T+P P P
Sbjct: 1286 TPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHP-------------------- 1325
Query: 427 HSFLTMSPRQTQASLTSPSRPASTPPD-SPPLQAPLSLPASPPLQTSLSPAVSPLSSPL- 484
T P T +T+ S P S + S P AP P+ P T +PA +S +
Sbjct: 1326 ---TTPDPSSTPV-ITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIP 1381
Query: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPP 544
T+ P AL S SP ++ M PL T+ PP P+L PP
Sbjct: 1382 TLEPSPALES----SPSRSSTATSMDPLSTED--------------FKPPRSQSPNLTPP 1423
Query: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP----PALAS 600
P TPH + +P PL +P + PP P ++ P Q+P P +A
Sbjct: 1424 PTH-------TPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVA- 1475
Query: 601 PPLQGLPSPPLSPLATPPP 619
P+PP+ +A PP
Sbjct: 1476 ------PTPPVRVMACEPP 1488
Score = 91.7 bits (226), Expect = 4e-18
Identities = 127/497 (25%), Positives = 169/497 (34%), Gaps = 50/497 (10%)
Query: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT-PPPET 583
TP A P L + +P S P H +T P P + PP P T P T
Sbjct: 952 TPTAGKLGPTLGAGTTRSP-----GSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPT 1006
Query: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP-PASPPL 642
PS P P A P P L S L+P + +A P +PP+P PAS
Sbjct: 1007 PS----PGPSASPGPPGPALTSDSSRELTPHSALTSEATSDA---PDTSPPTPDPASRTN 1059
Query: 643 SPLATPSPQ----APNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPS-QAP 696
L SP P++ V L SP P P + S P++P S +P S Q P
Sbjct: 1060 PDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVP 1119
Query: 697 PSLAAPPLQVPP----------SPPASPPMSPSATPPP-QAPPPLAAPPLQVPPSPPASP 745
S P L P SP SP P+ TP P AP P+ V P P +P
Sbjct: 1120 ESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTP 1179
Query: 746 PMSPSATP-PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
P+ TP P + P P P ++ S + P P T +Q +P
Sbjct: 1180 --HPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTT--MQPTTTPH 1235
Query: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
++ P ++ S + P P P P +P P T
Sbjct: 1236 STTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHP 1295
Query: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEELRGYDSGPEG 920
T+ P +T P P + P++T P SS + S P L S P
Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTTPDPTTT-PHPTTPDPSSTPVITTVSLPTSLGTELSSPTL 1354
Query: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 980
P + HP PAP + P P P S T +
Sbjct: 1355 APTVKP-------SLHPQLTFTAPAPHTSTSQIPTLE-PSPALESSPSRSSTATSMDPLS 1406
Query: 981 PESATPAPGALDPGPSP 997
E P P + P +P
Sbjct: 1407 TEDFKP-PRSQSPNLTP 1422
Score = 47.8 bits (112), Expect = 6e-05
Identities = 64/273 (23%), Positives = 94/273 (34%), Gaps = 45/273 (16%)
Query: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
P+ ++ ++ P L A + P SPP P P P
Sbjct: 943 PSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRT 1002
Query: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP--SPPASPTLQAP-RRP 858
+PP PG P A+P P P + + ++ P + + T AP P
Sbjct: 1003 APPTPSPG-------------PSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSP 1049
Query: 859 PTP------GPDTSVSGPRLTL-----ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907
PTP PD ++ P L ++ P P PS +P P L +S ST
Sbjct: 1050 PTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPL-----PTLPKELTSDPST 1104
Query: 908 PEELRGYDSGPEGGAAASPPPDAELA--ACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT- 964
P E+ E + PD + + + +SR P P +P P P T
Sbjct: 1105 PSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDP---------SPSPHPTTTP 1155
Query: 965 GPGSA-DGLCTIYETEGPESATPAPGALDPGPS 996
P A D + T+ T P T P P+
Sbjct: 1156 DPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPT 1188
Score = 41.6 bits (96), Expect = 0.004
Identities = 81/364 (22%), Positives = 119/364 (32%), Gaps = 43/364 (11%)
Query: 60 ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS---- 115
E AG + P PT S ++ R ASRPP S +AP SP P S
Sbjct: 397 EDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPP-STMTSQAPGTAGVSPPPASPTVL 455
Query: 116 -SPGRASGTTR----PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170
PG +G+ + GP G R+ G + SA R+ P
Sbjct: 456 WEPGPEAGSPQLRLVAGPSKCSG-RLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQ 514
Query: 171 TPSPAMARRSRAAG----TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
P PA R AG +VG S P + + + + T P
Sbjct: 515 QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLD 574
Query: 227 RPSAG------GGLQRPASRSLSSS-ATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQ 278
S GL R L AT S+ + + T +AP P K +
Sbjct: 575 SISDPFSWSWIPGLGRDRDAWLPGELATKPSASVTASVLEKTTTKAPGKMPKSTKKWVTK 634
Query: 279 ALRPPQVTPP--------RKDAAPALGPLSSSPLAT-----PSPSGTKARPVPPPDNAAT 325
+ P PP R + P L +++ L T P+ T+ P +
Sbjct: 635 NAKRPTTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTS 694
Query: 326 PLPATLPPSPP-------LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378
ATL P P +A P ++ +++++P P ++ P P
Sbjct: 695 HTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKD 754
Query: 379 APPS 382
PS
Sbjct: 755 PAPS 758
Score = 38.5 bits (88), Expect = 0.036
Identities = 40/146 (27%), Positives = 54/146 (36%), Gaps = 13/146 (8%)
Query: 790 PALATPPLQALPSPPASFPGQAPFS---PSASLPMSPLATPPPQAP---PVLAAPLLQVP 843
P ++P ++ LP + + P++ PS LA P A P L A + P
Sbjct: 915 PGSSSPAIRRLPDTGSKDGYKLPWTWDTPSGR----GLAEGTPTAGKLGPTLGAGTTRSP 970
Query: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 903
SPP P P P+ P T P P P PS SP GP L SS
Sbjct: 971 GSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGP--PGPALTS-DSS 1027
Query: 904 ATSTPEELRGYDSGPEGGAAASPPPD 929
TP ++ + + P PD
Sbjct: 1028 RELTPHSALTSEATSDAPDTSPPTPD 1053
Score = 35.4 bits (80), Expect = 0.31
Identities = 48/192 (25%), Positives = 69/192 (35%), Gaps = 22/192 (11%)
Query: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
A PG+ PSAS+ S L +AP + + PT Q P P T
Sbjct: 594 AWLPGELATKPSASVTASVLEKTTTKAPGKMPKSTKKWVTKNAKRPTTQPPVMPTTK-HS 652
Query: 865 TSVSGPRLTLALAPGPPPPPSRSPSS------TLSGPDLAGHSSSATSTPEELRGYDS-- 916
+ S P LT SR P+S T P ++AT TP+ R +
Sbjct: 653 RAQSPPDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHTTATLTPQAPRERTTKT 712
Query: 917 -------GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969
GP+ + S A+ P+A +P +P P P P + G +
Sbjct: 713 MAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPE-----SPKDPAPSPSVSTTGES 767
Query: 970 DGLCTIYETEGP 981
GL + +GP
Sbjct: 768 -GLFRVRLADGP 778
Score = 32.7 bits (73), Expect = 2.0
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 9/60 (15%)
Query: 780 PLAKPPPQAPP-ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 838
PL PP AP + + P +A PP++ QAP + S PPP +P VL P
Sbjct: 407 PLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVS--------PPPASPTVLWEP 458
Score = 32.0 bits (71), Expect = 3.4
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
+ +P PP + +TP P+ QAP + +PPP +P+ + P P+A
Sbjct: 404 DGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEA- 462
Query: 596 PALASPPLQGLPSP 609
SP L+ + P
Sbjct: 463 ---GSPQLRLVAGP 473
Score = 31.2 bits (69), Expect = 5.8
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 8/62 (12%)
Query: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
PP+ P + S P P +T SQAP + P PPASP + P P+A
Sbjct: 412 PPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSP------PPASPTV--LWEPGPEAG 463
Query: 728 PP 729
P
Sbjct: 464 SP 465
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 150 bits (380), Expect = 5e-36
Identities = 244/913 (26%), Positives = 320/913 (35%), Gaps = 161/913 (17%)
Query: 207 KSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
+S+ + HS+ SP S G RP R P ++P GP + P
Sbjct: 115 RSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCR------VPPTTPLNGGPGS--LPP 166
Query: 265 APAHPSQPKPK--GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD- 321
P SQ P G L PP++ P P+ G SSSP P + P PPP
Sbjct: 167 EPPSVSQAFPTLAGPGGLFPPRLADP----VPSGG--SSSPRFLPRGNAPSPAPPPPPAI 220
Query: 322 -------NAATPLPATLPPSPPLATPLPLAPPSPSAPPSL---QTLPSPPATPPSQAPPS 371
N L ++L PS + P P A SP + P L +PP PPS P+
Sbjct: 221 SLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPA 280
Query: 372 MTTPPMQAPPSLQTIP-PIQVPHSLTSPSLQAPPSP--LALSSLQATTSLGSPTLQATHS 428
P Q P S T+ P+ + +P+++ P +P LA S L A P L +
Sbjct: 281 HPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPST 340
Query: 429 FLTMSPRQT--QASLTSPSRPASTPPDSPPLQAPLSL---PASPPLQTSLSPAV--SPLS 481
PR AS +S RP+ P PP L P +P +PA P S
Sbjct: 341 LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFS 400
Query: 482 SPLTIHPL--QALSSLASHSPQAPLSS---------LIMPPLETQSSLAPPS----LQTP 526
P P+ LS L +P S +PP T SS +PP +Q
Sbjct: 401 LPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPS 460
Query: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP------CPAPCPLQAPPSPLTTPP 580
T+ L ++P PP + + + +P L++P CPL P
Sbjct: 461 LPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPF 520
Query: 581 PETPSSIATPPPQAPPALASPPLQ-GLPSPPLSPLAT-------------PPPQAPPXLA 626
P +A P L + PL L PP SPL PPP+
Sbjct: 521 PSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPE------ 574
Query: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS---PPPSPP---VQAPFSP- 679
PL PP P PPL+P P+ P+ L LL P S PPPS P + A F P
Sbjct: 575 --PLLPPPGGPG-PPLAP---GEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPL 628
Query: 680 -------------------PASPP------VSPSATPPSQAPPSLAA---PPLQVPPSPP 711
P+ P +SP PP APP+L A L PP
Sbjct: 629 LALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPP 688
Query: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT--PPPRVPPLLAAPPLQVP 769
+ P P PQ PP ++ +S +PS + PP + PLL A L
Sbjct: 689 SGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLL--- 745
Query: 770 PSPPASLPMSPLAKPP---PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
+SL SP A P P P LQ LP A P SP A L S L
Sbjct: 746 -GDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQS-LQI 803
Query: 827 PPPQA-----PPVLAAPLLQVPPSPPASPTLQAPRRPPTP-------GPDTSVSGPRLTL 874
PP Q PP A L+ P+ P L P P P G + G R
Sbjct: 804 PPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGG 863
Query: 875 AL---------APGPPPPPSRSPSS-TLSGPDLAGHSSSATSTPEELRGYDSG---PEGG 921
L A G P R P L G + +P + EGG
Sbjct: 864 GLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG 923
Query: 922 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 981
A PP P + P + + G + P S+ T+ +
Sbjct: 924 AEPKDPPPP-----GPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTA 978
Query: 982 ESATPAPGALDPG 994
+A P P PG
Sbjct: 979 RAAVPLPPRARPG 991
Score = 139 bits (349), Expect = 2e-32
Identities = 196/677 (28%), Positives = 242/677 (35%), Gaps = 129/677 (19%)
Query: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPA 91
SP PPPP + GA R L G A S+P + P + + P
Sbjct: 211 SPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPP 270
Query: 92 SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP----GPLGQKGLRISAEETVARGKA 147
PP++ PA PGP S P +S T GPLG TV A
Sbjct: 271 PLPPSNNL-----PAH---PGPASQPPVSSATMHLPLVLGPLG-------GAPTVEGPGA 315
Query: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA---AGTEVGLPRPAPSARPRPPT-- 202
S LSA A+ P PS RR RA + + RP+ RPPT
Sbjct: 316 PPFLASSLLSAAAK--AQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
Query: 203 -----EGPRKSVSSASEHSTTEPSPAARRRPSAGG--------GLQRPASRSLSSSATPL 249
GP+ S P P + PS GL P S L
Sbjct: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLL 433
Query: 250 SSPARSGPS---ARGTPRAPAHPSQPK----PKGLQALRPPQVTPPRKDAAPAL-GPLSS 301
S A P + G+P P HP QP G + P PP AP + P+
Sbjct: 434 GSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQ 493
Query: 302 SPL---------ATPSP--SGTKARPVPPPDNA-------------ATPLPATL---PPS 334
SP A P P +G +A P P P+ A PLP +L PPS
Sbjct: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
Query: 335 PPLATPL--------PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386
P L L PP P PP P PP P PS+ + PP +
Sbjct: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGG--PGPPLAPGEPEGPSLLVASLLPPPPSDLL 611
Query: 387 PPIQVPHSLTSPSL-------------------QAPPSPLALSSLQATTSLGSPTLQATH 427
PP P S S PS S L + L P L A
Sbjct: 612 PPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPP 671
Query: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS-PAVSPLSSPLTI 486
+ + ++ A+L PS TPP L AP P + + T+ + P S L +
Sbjct: 672 TLIALNSALLAATLDPPS---GTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSN 728
Query: 487 --HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL--ENLPSL- 541
P Q LS L S LSSL T S A PSL PP L + L + LP
Sbjct: 729 SGRPPQLLSPLLGASLLGDLSSL------TSSPGALPSLLQPPGPLLSGQLGLQLLPGGG 782
Query: 542 APPPLQTASAPLTT--PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
APPPL AS+PL L+ PP + P +P PPE+P+S P P PP A
Sbjct: 783 APPPLSEASSPLACLLQSLQIPP-------EQPEAPCL--PPESPASALEPEPARPPLSA 833
Query: 600 SPPLQGLPSPPLSPLAT 616
P G P PP+ L T
Sbjct: 834 LAPPHGSPDPPVPELLT 850
Score = 126 bits (316), Expect = 1e-28
Identities = 200/736 (27%), Positives = 263/736 (35%), Gaps = 162/736 (22%)
Query: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516
L+ PL++P L+P V+P + + + ++ L +H +A + + +ET
Sbjct: 64 LECPLNVPKVFNFDP-LAP-VTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTC 121
Query: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP--CPLQAPPS 574
S + P +P + + S PP + PPC P PL P
Sbjct: 122 S------HSSPGEGASPQMFHTVSPGPPSAR-------------PPCRVPPTTPLNGGPG 162
Query: 575 PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
L PPE PS QA P LA P GL P L+ + P LP AP
Sbjct: 163 SL---PPEPPSV-----SQAFPTLAGPG--GLFPPRLADPVPSGGSSSPRF-LPRGNAPS 211
Query: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---SPSATP 691
P PP L PS AL L+ + PP+P A SPP+ PP+ S + TP
Sbjct: 212 PAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAP--HASSSPPSDPPLFHCSDALTP 269
Query: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751
P PPS P P P + PP+S + P PL P P +PP S+
Sbjct: 270 P-PLPPSNNLP---AHPGPASQPPVSSATMHLPLVLGPLGGAP---TVEGPGAPPFLASS 322
Query: 752 TPPPRVPPLLAAPPLQVPPSPPASLPMS--PLAKPPPQAPPALATPPLQALPSPPASF-- 807
L AA Q PP PP S P A+ P + + P + PP F
Sbjct: 323 L-------LSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRL 375
Query: 808 -PGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LLQVP-PSP------------ 846
G+ P +P S P +P P P + P + P LL +P P P
Sbjct: 376 LEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGS 435
Query: 847 ----PASPTLQA-----PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897
P PTL + PR P P + SG +L+ PG P PP+ S + + P L
Sbjct: 436 DAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSG---SLSSVPGAPAPPAASKAPVVPSPVL 492
Query: 898 AGHSSSATSTPEELRGYDSGPE--------GGAAASPPPDAELA----------ACHPAA 939
+P E G +GP G A P P+ LA P
Sbjct: 493 --------QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLP 544
Query: 940 WSRGPAPPL---------AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT----- 985
S G PP G G P P P PG E EGP
Sbjct: 545 LSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLP 604
Query: 986 PAPGALDPGPSP----------------GTSGGKAAAGAGAGASSRSPKQARLGEL-PL- 1027
P P L P PS T+G + GAG S P LG+L PL
Sbjct: 605 PPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSG-LGDLSPLL 663
Query: 1028 -GALQASVVQHLLSRTLLLAAAEGAAGG-------SGGGPGGAEGGGVT-----GGARAA 1074
L A L+ LL A + +G S PG T G +
Sbjct: 664 FPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLG 723
Query: 1075 LSDAELGRWAELLSPL 1090
+ + GR +LLSPL
Sbjct: 724 KAPSNSGRPPQLLSPL 739
Score = 48.9 bits (115), Expect = 3e-05
Identities = 74/274 (27%), Positives = 99/274 (36%), Gaps = 58/274 (21%)
Query: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATIPESAPR 76
+PG L P +PP P+ L + G PL+E + + IP P
Sbjct: 754 SPGAL----PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE 809
Query: 77 AG--PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLGQKG 133
A P S ++ +RPP S APP + P P GR SG + G G G
Sbjct: 810 APCLPPESPASALEPEPARPPLSAL---APPHGSPDPPVPELLTGRGSG--KRGRRGGGG 864
Query: 134 LR-ISAEETVARGK---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
LR I+ E ARG+ + P R AL G R +G +P + E G
Sbjct: 865 LRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGA 924
Query: 190 -----PRPAP--------------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
P P P S R R P ++ +S+ + T EPSP AR
Sbjct: 925 EPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTAR----- 979
Query: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
+A PL AR G A+ R
Sbjct: 980 --------------AAVPLPPRARPGRPAKNKRR 999
Score = 35.4 bits (80), Expect = 0.31
Identities = 79/313 (25%), Positives = 111/313 (35%), Gaps = 49/313 (15%)
Query: 73 SAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSP-----------GPVSSPGRA 120
SAP+ GP T S T++ +P + P + SP SSPG
Sbjct: 699 SAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGAL 758
Query: 121 SGTTRP-GPL--GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
+P GPL GQ GL++ G + S+ A + P +P +
Sbjct: 759 PSLLQPPGPLLSGQLGLQLLP----GGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLP 814
Query: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ-- 235
S A+ E RP SA PP P V E T S RR GGGL+
Sbjct: 815 PESPASALEPEPARPPLSALA-PPHGSPDPPVP---ELLTGRGSGKRGRR--GGGGLRGI 868
Query: 236 ----RPA-SRSLSSSATP----LSSPARSGPSARGTPRAPA------HPSQPKPKGLQAL 280
RPA R S P L R G + + R+P H + G +
Sbjct: 869 NGEARPARGRKPGSRREPGRLALKWGTRGGFNGQ-MERSPRRTHHWQHNGELAEGGAEPK 927
Query: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
PP P +D G + S G + + P ++ ++ TL PSP
Sbjct: 928 DPPPPGPHSEDLKVPPG------VVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAA 981
Query: 341 LPLAPPSPSAPPS 353
+PL P + P+
Sbjct: 982 VPLPPRARPGRPA 994
Score = 32.0 bits (71), Expect = 3.4
Identities = 53/204 (25%), Positives = 75/204 (36%), Gaps = 25/204 (12%)
Query: 12 AAARTPAARAPGLLTPRPP-GSPRPPPP--VTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
A+A P P L PP GSP PP P +T G G G + GI G
Sbjct: 819 ASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLR-------GINGE 871
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN--TSPGPVSSPGRASGTTRP 126
P + G R G + +R +G+ ER+P + G ++ G + P
Sbjct: 872 ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG--AEPKDP 929
Query: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
P G + V R K+ +R + PSP +RAA
Sbjct: 930 PPPGPHSEDLKVPPGVVR-KSRRGRRRKYNPTRNSNSSRQDITLEPSPT----ARAA--- 981
Query: 187 VGLPRPAPSARPRPPTEGPRKSVS 210
V LP P ARP P + R+ ++
Sbjct: 982 VPLP---PRARPGRPAKNKRRKLA 1002
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 149 bits (375), Expect = 2e-35
Identities = 238/972 (24%), Positives = 337/972 (34%), Gaps = 222/972 (22%)
Query: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 63 GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
+ G ++ S P + S+ P +P + P + + PGP P + SG
Sbjct: 287 DIVRGESVKPSLP---------SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
T+ PL Q+ PGT P + +
Sbjct: 338 LTK--PLAQQ------------------------------------PGTVKPPV----QP 355
Query: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
GT P A+P P + P + S + S+ +P P A +P G
Sbjct: 356 PGT------TKPPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQPPGVG---------- 398
Query: 243 SSSATPLSSPARSGPSAR--GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
TP P + P + GTP+ A QP GLQ+ P + P K GP
Sbjct: 399 ---KTPAQQPGPAKPPTQQVGTPKPLA--QQP---GLQS--PAKAPGPTKTPVQQPGP-G 447
Query: 301 SSPLATPSPSGTKAR---PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
P P T A+ P PP + P PA PP P P P + PPS Q
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ-- 503
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
P PP Q P+ +P Q P S T PP Q P S PS Q PSP S+ Q+T
Sbjct: 504 PGSTKPPPQQPGPAKPSP--QQPGS--TKPPSQQPGS-AKPSAQ-QPSPAKPSAQQST-- 555
Query: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLSP 475
+P S PLQ P P++ PP Q
Sbjct: 556 ----------------------------KPVSQTGSGKPLQPPTVSPSAKQPPSQ----- 582
Query: 476 AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT--- 532
P TI PL + L H P+ + E Q+++ P LT
Sbjct: 583 -----GLPKTICPLCNTTELLLHVPE---KANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
Query: 533 -------------PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579
L +PS P L+T AP+TT + P P SP
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKT--APVTTTSAVSKSSPQP----QQTSPKKDA 688
Query: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
P+ S A P + PP + P L G PS A PP+A L+ P PS P+
Sbjct: 689 APKQDLSKAPEPKKPPPLVKQPTLHGSPSAK----AKQPPEA-DSLSKPAPPKEPSVPSE 743
Query: 640 PPLSPLATPSPQAPNAL-----AVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPS 693
+P+A P+ P + V A P PS VQ+ +PP+ + PS
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
Query: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP---------LQVPPSPPAS 744
Q+ PP+ P A P P + + + P QV P
Sbjct: 804 QS----------FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 745 PPMSPSA--TPPPRVPPLLAAPPLQVPPSPPASLPM-SPLAKPPPQ-------------- 787
P +P P P+ P P P A + +P P PQ
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 788 -APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
AP + T P + + F G + FS +++L +S P P + AP+ Q P+P
Sbjct: 914 DAPKSQPTTPQETVTGKLFGF-GASIFSQASNL-ISTAGQPGPHSQSGPGAPMKQA-PAP 970
Query: 847 PASPTLQAP-----RRPPTPGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLA 898
PT Q P + PP P V A L P P+ + T P
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPI 1030
Query: 899 GHSSSATSTPEE 910
S S T+ P++
Sbjct: 1031 KDSKSLTAEPQK 1042
Score = 145 bits (365), Expect = 3e-34
Identities = 266/1055 (25%), Positives = 372/1055 (35%), Gaps = 164/1055 (15%)
Query: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAGPT-RSAGT 85
G+ P PA + L R+ +A RA G+ ++P +A + R
Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQEL 87
Query: 86 SSRNP---ASRPPASGRGERAPPAKNTSPGPVSS----PGRASGT-TRPGPLGQKGLRIS 137
S +P + RPP GR + +K+ + S PGR+ T + + L+
Sbjct: 88 DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE 147
Query: 138 AEETVARGKATEAPKRSALSAGARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 191
+ ++ G +E SA+S+ + D + + ++ + E G P
Sbjct: 148 HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET-TKKQKVVQKEQGKPEGI 206
Query: 192 ---------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
P P + + P P + + S+ +P + P G +Q P
Sbjct: 207 IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ 266
Query: 243 SSSAT-PLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTP--PRKDA 292
+ A PL A + RG P+ PS KP Q +PP P +
Sbjct: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 293 APALGPLSSSPLATP--SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
PA P S L P GT PV PP T PP+ PL P A + S
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT-------TKPPAQPLGPAKPPAQQTGSE 379
Query: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAP---PSP 406
PS + P P A +Q P TP Q P+ + P L P LQ+P P P
Sbjct: 380 KPSSEQ-PGPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP 436
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
+ +Q P QA P +T A T P++P S P PA
Sbjct: 437 TK-TPVQQPGPGKIPAQQA-------GPGKTSAQQTGPTKPPSQLPG----------PAK 478
Query: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
PP Q PA P PQ P S+ PP + S PP Q
Sbjct: 479 PPPQQP-GPAKPP--------------------PQQPGSA--KPPSQQPGSTKPPPQQPG 515
Query: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
PA P + S PP Q SA P P P + T P +T S
Sbjct: 516 PAK---PSPQQPGSTKPPSQQPGSAK--------PSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 587 IATPPPQAPPALASPPLQGLPSP--PL---SPLATPPPQAPPXLALPPLQAP-------- 633
PP P+ PP QGLP PL + L P+ Q
Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
Query: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
P+P + L + Q AL L P SP P AP + ++ VS S+ P
Sbjct: 625 PNPHLTEVKEWLCL-NCQMKRALGGDLAPVPSSPQPKLKT-APVTTTSA--VSKSSPQPQ 680
Query: 694 QAPPSLAAPP---LQVPPSPPASPPM--------SPS--ATPPPQAPPPLAAPPLQVPPS 740
Q P A P L P P PP+ SPS A PP+A L+ P PS
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA-DSLSKPAPPKEPS 739
Query: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
P+ +P A P+ P ++ V S + P P +K QA TPPL+
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK-TTPPLKTD 798
Query: 801 PSPPA-SFPGQ----APF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPP-----SPPAS 849
+ P+ SFP +PF S + P S P + QV P P +
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858
Query: 850 PTLQAPRRPPTPGPDTSVS--GPRLTLA-LAPGP---PPPPSRSPSSTLSGPDLAGHSSS 903
T +P+ P P S + GPR T P P P P +S +L+ + S
Sbjct: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
Query: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFRGAPGAPLPWPP 962
+TP+E G + S + A P S+ GP P+ AP P P
Sbjct: 919 QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP---PT 975
Query: 963 ATGPGSADGLCTIYETEG----PESATPAPGALDP 993
+ GP + G + E+ PA L+P
Sbjct: 976 SQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
Score = 142 bits (359), Expect = 1e-33
Identities = 229/915 (25%), Positives = 303/915 (33%), Gaps = 150/915 (16%)
Query: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
+A + A G G P+ +A P G +S SE + + R G
Sbjct: 16 LAAAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71
Query: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---KPKGLQALRPPQVTPPRKDA 292
PA+ S + P G P P P+QP K + R Q P R
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--- 128
Query: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
+P+ L S T K+ +P + L A S + P S S
Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAV---SSVVNKFNPFDLISDSEAS 185
Query: 353 SLQTLPSPPATPPSQAPPS-MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
+T Q P + PP+Q P + IP Q P LQ +P ++SS
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPP-KPIPKQQGPGR---DPLQQDGTPKSISS 241
Query: 412 LQATTSLGSP------------TLQATHSFLTMS-----PRQTQASLTSPS--RPASTPP 452
Q P T Q H+ L + P+ QA + +P+ P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Query: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
PP+Q P P PP Q P S P A S L P
Sbjct: 302 SKPPIQQPT--PGKPPAQ----------------QPGHEKSQPGPAKPPAQPSGLTKPLA 343
Query: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572
+ ++ PP P T PP + L PP QT S ++ P P L P
Sbjct: 344 QQPGTVKPP---VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ------PGPKALAQP 394
Query: 573 PSPLTTPPPETPSSIATPPPQ---APPALASPPLQGLPSPPLSPLATPPP-QAPPXLALP 628
P TP + A PP Q P LA P GL SP +P T P Q P +P
Sbjct: 395 PGVGKTPAQQPGP--AKPPTQQVGTPKPLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIP 450
Query: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
QA P ++ P PS L P PPP P P PP P S
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQ----------LPGPAKPPPQQP--GPAKPPPQQP--GS 496
Query: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
A PPSQ P S PP Q P+ P+ P P +T PP P A P Q P PA P
Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKPS--PQQPGSTKPPSQQPGSAKPSAQQPS--PAKPSAQ 552
Query: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
S P V + PLQ P +SP AK PP PL P
Sbjct: 553 QSTKP---VSQTGSGKPLQPPT-------VSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Query: 809 GQAPFSPSASLPMSPLA----TPPP-------------QAPPVLAAPLLQVPPSP----- 846
+A F+ + + P P Q L L VP SP
Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662
Query: 847 --PASPTLQAPRRPPTPGPDT--SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
P + T + P P + + P+ L+ AP P PP + P L G S
Sbjct: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP-----PLVKQPTLHGSPS 717
Query: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
+ P PE + + P P E P+ S P+A P P P
Sbjct: 718 AKAKQP---------PEADSLSKPAPPKE-----PSVPSEQDKAPVA-DDKPKQPKMVKP 762
Query: 963 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 1022
T S+ T + + P S + P T K + SP ++
Sbjct: 763 TTDLVSSSSATT--KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK- 819
Query: 1023 GELPLGALQASVVQH 1037
+P A + ++ H
Sbjct: 820 -AIPRPASDSKIISH 833
Score = 107 bits (266), Expect = 8e-23
Identities = 201/850 (23%), Positives = 288/850 (33%), Gaps = 170/850 (20%)
Query: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 66 GGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNTSPGPV----SSPG 118
G + P PT+ GT ++ P + PA G P + PG + + PG
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 119 RAS----GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
+ S G T+P P G + K SA + ++ P P P P
Sbjct: 458 KTSAQQTGPTKP-PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Query: 175 AMARRSRAAGTEVGLPRPA---PSAR-PRPPTEGPRKSVSSASEHSTTEP------SPAA 224
A + T+ +P PSA+ P P ++S S+ + +P SP+A
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Query: 225 RRRPSAGGG-------------LQRPASRSLSSSA---TPLSSPARSGPS---------- 258
++ PS G L P + ++ T + S P+
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 259 --------ARGTPRAPAHPSQPKPK----------GLQALRP-PQVTPPRKDAAPALG-- 297
A G AP PS P+PK + P PQ T P+KDAAP
Sbjct: 637 CLNCQMKRALGGDLAPV-PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
Query: 298 ---------PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
PL P SPS KA+ P D+ + P P P P P+A P
Sbjct: 696 KAPEPKKPPPLVKQPTLHGSPSA-KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 349 SAP----PSLQTLPSPPATPPSQAPPS--------MTTPPMQ---APPSLQTIPPIQVPH 393
P P+ + S AT P S TTPP++ A PS P +
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS 814
Query: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
S ++ P S + S +S Q P++ Q + S PD
Sbjct: 815 PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM-------SPKPD 867
Query: 454 SPPLQAPLSLPASP-PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
+ P+ P P P P T+ +P SP Q+ SL + +
Sbjct: 868 AKPM--PKGSPTPPGPRPTAGQTVPTPQQSP-------------KPQEQSRRFSLNLGSI 912
Query: 513 ETQSSLAPPSLQTPPASLTTPPL----ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
AP S T P T L ++ S A + TA P PH ++ P
Sbjct: 913 TD----APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP--GPHSQSGPGAPMKQ 966
Query: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL- 627
AP P T+ P P S PP PA + P + +P L QAP
Sbjct: 967 APAPSQPPTSQGP--PKSTGQAPP--APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 628 -----PPLQAPPSPPASPPLSPLAT-----PSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
PP++ S A P + L T P P++ L L PP+
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
Query: 678 SPPASPPVSPSATP-------------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
+ TP +Q S ++ P P+ P SP P
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
Query: 725 QAPPPLAAPP 734
+ A PP
Sbjct: 1143 SSSQKTAVPP 1152
Score = 82.8 bits (203), Expect = 2e-15
Identities = 160/700 (22%), Positives = 239/700 (34%), Gaps = 92/700 (13%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G+ P P +P+ PGS +PP +A A KP A++
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--SAQQPSPAKPSAQQ-- 553
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
+T P S +G T S + A +PP+ G + P NT+ + P +A+
Sbjct: 554 ----STKPVSQTGSGKPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 124 TRPGPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPS 173
T + TV TE + L+ +R G P P +P
Sbjct: 609 T----------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
Query: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSA 230
P + + V P P P++ +S A E P P PSA
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 231 GGGLQRPASRSLSSSATP----LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQ 284
Q P + SLS A P + S P A P+ P P+ A P
Sbjct: 719 -KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
Query: 285 V------TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
+ + + P L S+ P + P+G K V P D+ A P PA+ S ++
Sbjct: 778 IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK---VSPFDSKAIPRPAS--DSKIIS 832
Query: 339 TPLPLAP----------PSPSAPPSLQT--LPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386
P P + P QT P P A P + P TPP P + QT+
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP---TPPGPRPTAGQTV 889
Query: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT-----HSFLTMSPRQTQASL 441
P P P Q+ L L S+ T Q T F Q +
Sbjct: 890 P---TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 442 TSPSRP---ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
++ +P + + P +P QAP P+ PP TS P S +P P A S
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAP--APSQPP--TSQGPPKSTGQAP----PAPAKSIPVKK 998
Query: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
+AP + + P E P+++ PP+++ SL P A L T
Sbjct: 999 ETKAPAAEKLEPKAE-----QAPTVKRTETEKKPPPIKDSKSLTAEP---QKAVLPTKLE 1050
Query: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP 618
++P + CPL + + P ++ Q P L
Sbjct: 1051 KSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110
Query: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 658
Q L ++ P P+ P SP+ P+ + AV
Sbjct: 1111 TQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
Score = 77.8 bits (190), Expect = 5e-14
Identities = 106/362 (29%), Positives = 134/362 (37%), Gaps = 49/362 (13%)
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGT----PRAPAHPSQPKPKGLQALRPPQVTPP 288
G ++PAS+ S S + S PA+ P R + P P P P PP PP
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP-------PPPPPPP 2420
Query: 289 RKDAAPALGPLSSSPLATPSPSGTKARPV---PPPDNAATPLPAT-------LPPSPPLA 338
P P S P P T A PV P +A T L T LP +
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480
Query: 339 TPLPLAPPSPSAPPS---LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
T P PP PS+ PS P P P + P P P+ I P SL
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPT--DIHPKPTGLSL 2538
Query: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
TS S+ A L + TS SP + + S +T +T PS P TP DS
Sbjct: 2539 TS-SMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP-GTPTDSS 2596
Query: 456 PLQAPLSLPASPPLQ--TSLSPAVS----------PLSSPLTIHPLQALSSLASHSPQAP 503
QA S P P + S+ P S P+SS T + AL + ++ AP
Sbjct: 2597 ASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656
Query: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA----PPPLQTASAPLTTPHLE 559
S P TQ S A+ +T P L S++ P PL L HLE
Sbjct: 2657 SSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL-----ALDNIHLE 2711
Query: 560 TP 561
P
Sbjct: 2712 KP 2713
Score = 71.6 bits (174), Expect = 4e-12
Identities = 71/259 (27%), Positives = 96/259 (37%), Gaps = 25/259 (9%)
Query: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT------PPSQAP---PSLAAPPLQVPPSP 710
L + F PPS + P S S P SQ P PS+++ P + P
Sbjct: 2335 LSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF 2394
Query: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
+S + PPP PPP PP PP PP PP SP T P+ +A+P P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 771 SPPASLPMSPLAKPPPQAPPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
A + A P + T +P P+S P F+ P
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT----------HRPE 2504
Query: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
P PP+ P++ P+ PT P +P +S++ +T A P P SP
Sbjct: 2505 PSKPPIAPKPVIPQLPTTTQKPTDIHP-KPTGLSLTSSMTLNLVTSADYKLPSPTSPLSP 2563
Query: 889 SSTLSGPDLAGHSSSATST 907
S S P S S T T
Sbjct: 2564 HSNKSSPRF---SKSLTET 2579
Score = 61.2 bits (147), Expect = 5e-09
Identities = 91/376 (24%), Positives = 135/376 (35%), Gaps = 57/376 (15%)
Query: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
T+SSL+ PP+S+ P++ L+T + + + P
Sbjct: 2331 TKSSLSETVFDHPPSSVIALPMKE--------------QLSTTYFTSGETFGQ---EKPA 2373
Query: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
S L + P S A P P + Q P PP P PPP PP P
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP--PP---------P 2422
Query: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
P PP PP SP T P+ +A + A +P A + + + + P +
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTA------TPLFDAVTTLETTAVLRSNGLPVT 2476
Query: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
+ APP VPP P + P P + PP+A P V P P + P
Sbjct: 2477 RI--CTTAPP-PVPPKPSSIPSGLVFTHRPEPSKPPIAPKP--VIPQLPTTTQKPTDIHP 2531
Query: 754 PPRVPPLLAAPPLQVPPSPPASL--PMSPLAKPPPQAPPALA-----TPPLQALPSPPAS 806
P L ++ L + S L P SPL+ ++ P + T + LPS P +
Sbjct: 2532 KPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT 2591
Query: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
S S ++ PL +P + L+ V P P + A P +
Sbjct: 2592 ---PTDSSASQAITSWPLGSP--------SKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 867 VSGPRLTLALAPGPPP 882
+SG T + P P
Sbjct: 2641 ISGALQTFSATPVTAP 2656
Score = 59.7 bits (143), Expect = 2e-08
Identities = 109/471 (23%), Positives = 165/471 (35%), Gaps = 79/471 (16%)
Query: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
P V ++++ L + P+ + + + L+A + +T++SL+
Sbjct: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSE--- 2337
Query: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
T D PP + ++LP L T+ +S T + S L S SP +SS
Sbjct: 2338 ---TVFDHPP-SSVIALPMKEQLSTTY------FTSGETFGQEKPASQLPSGSPS--VSS 2385
Query: 507 LIMPPLE-TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565
L P +SS S Q PP PP PPP PP P
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPP--------PPP--------------PPPPPP 2423
Query: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPP---------ALASPPLQGLP-------SP 609
P PL P SP T P+ ++A+P A P A GLP +P
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASP-PLSPLATPSPQAP-------------NA 655
P P+ P P L P PP +P P+ P + Q P ++
Sbjct: 2484 P--PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS 2541
Query: 656 LAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
+ ++L+ + PSP +P S +SP S S T + L P P
Sbjct: 2542 MTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT------ETYVVITLPSEPGTPTDS 2595
Query: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
S + T P P + + V P PP++ P + LQ + P
Sbjct: 2596 SASQAITSWPLGSP--SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPV 2653
Query: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
+ P S A P + + ++ P S S ++P PLA
Sbjct: 2654 TAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLA 2704
Score = 55.5 bits (132), Expect = 3e-07
Identities = 116/521 (22%), Positives = 172/521 (33%), Gaps = 97/521 (18%)
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 220
P P P S + P P P P PP P + + + T
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446
Query: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
SP P + L S+ P++ + P P P PS P GL
Sbjct: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500
Query: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
P+ + P P + L P T P T P P + + + L S P
Sbjct: 2501 HRPEPSKPPIAPKPVIPQL---PTTTQKP--TDIHPKPTGLSLTSSMTLNLVTSADYKLP 2555
Query: 341 LPLAPPSPSAPPS-------------LQTLPSPPATP-PSQAPPSMTTPPMQAP------ 380
P +P SP + S + TLPS P TP S A ++T+ P+ +P
Sbjct: 2556 SPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVS 2615
Query: 381 --PSLQTIPP---IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS----FLT 431
P +PP +++P S S Q AL + AT + QA + FLT
Sbjct: 2616 VEPVFSVVPPVTAVEIPIS----SEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLT 2671
Query: 432 MSPRQTQASLTSPSRPA--------STPP-----DSPPLQAP--------------LSLP 464
+T+ S T + P+ + PP D+ L+ P + L
Sbjct: 2672 TEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLR 2731
Query: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
P ++ + LS+ Q ++ + + I+ T S + P SL
Sbjct: 2732 TVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLA 2791
Query: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
T + T + L A +TT PLQ S PP P
Sbjct: 2792 TETVTFVTCTASASYTTGTESLVGAEHAMTT------------PLQLTTSKHAEPPYRIP 2839
Query: 585 SSIATP--PPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
S P +AP L+ G P+ ++ T P PP
Sbjct: 2840 SDQVFPIAREEAPINLS----LGTPAHAVTLAITKPVTVPP 2876
Score = 42.4 bits (98), Expect = 0.003
Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 56/154 (36%)
Query: 769 PPSPPASLPMSPLA--------------KPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
PPS +LPM KP Q P +P + +LP+ P PF
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG--SPSVSSLPAKPR------PFF 2394
Query: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
S+SL +S A PPP PP PP PP P PP P P
Sbjct: 2395 RSSSLDIS--AQPPPPPPP---------PPPPPPPP-------PPPPPP----------- 2425
Query: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908
P PPP+ + L L S T+TP
Sbjct: 2426 -----PLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 38.9 bits (89), Expect = 0.028
Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 18/160 (11%)
Query: 304 LATPSPSGTKARPVPPPDNAATPLPAT----LPPSPPLATPL---PLAPPSPSAPPSLQT 356
L+ SP K RP P ++ L A L PSPP + + P++P SP
Sbjct: 3581 LSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAF 3640
Query: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
+P P +P + P M P + S++ P P SP A S +A
Sbjct: 3641 VPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK---PLSPTADESSRA-- 3695
Query: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456
Q T + T QT S + + T P+ PP
Sbjct: 3696 -----PFQYTEGYTTKG-SQTMTSSGAQKKVKRTLPNPPP 3729
Score = 34.7 bits (78), Expect = 0.52
Identities = 31/127 (24%), Positives = 46/127 (36%), Gaps = 6/127 (4%)
Query: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP-PPRVPPLLAAPPLQ 767
S SP + +PP P PL++ S + P PP+ P +L +P
Sbjct: 3573 SDTQSPQYLSATSPPKDKKRPT---PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629
Query: 768 VPPSPPASLPMSPLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
+ P P KP P +P + P + +P S S P+SP A
Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTA 3689
Query: 826 TPPPQAP 832
+AP
Sbjct: 3690 DESSRAP 3696
Score = 33.9 bits (76), Expect = 0.89
Identities = 53/179 (29%), Positives = 76/179 (42%), Gaps = 24/179 (13%)
Query: 382 SLQTIPPIQVPH----SLTSPSLQAPPSPLA-----LSSLQATTSLGSPTLQATHSFLTM 432
++QT+ I V ++ +PS++A +S+ + T GS Q T
Sbjct: 3517 AVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQ 3576
Query: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSP--LSSPLT-IH 487
SP+ A TSP + P PL+ S L A +Q + SP SP L SP++ +
Sbjct: 3577 SPQYLSA--TSPPKDKKRPT---PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
Query: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
P +AL S A + PL I P Q L P + PPAS T + P PL
Sbjct: 3632 PGKALES-AFVPYEKPLPDDISP----QKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685
Score = 33.9 bits (76), Expect = 0.89
Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 18/168 (10%)
Query: 351 PPSLQTLPS--PPATPPSQAPPSMTTPPMQAPPSL--------QTIPPIQVPHSLTSPSL 400
PP QT PP +P +Q S P QAP S QT+ QV T P+
Sbjct: 3869 PPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTF 3928
Query: 401 QAPPSPLALSSLQAT-TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
QA + +Q T T S L + + PRQT L P T
Sbjct: 3929 QAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYL----EPKITSNYEVIRNQ 3984
Query: 460 PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507
PL + P+ T + AVS L S L+ S +P+SS+
Sbjct: 3985 PLMI---APVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSI 4029
Score = 32.7 bits (73), Expect = 2.0
Identities = 104/482 (21%), Positives = 154/482 (31%), Gaps = 79/482 (16%)
Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
+A+ P P PP P PPPP P + K A + AT A
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
T + S+ P +R + APP P P S P T RP P
Sbjct: 2462 LETTAVLRSNGLPVTRICTT-----APPP--VPPKPSSIPSGLVFTHRPEP--------- 2505
Query: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGLPR 191
K APK + T PT P P + + + LP
Sbjct: 2506 -------SKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPS 2556
Query: 192 PAPSARPRPPTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
P P PR S S + T PS G +S S + ++ PL
Sbjct: 2557 PTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP---------GTPTDSSASQAITSWPLG 2607
Query: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQ-------------ALRPPQVTPPRKDAAPALG 297
SP++ S P P ++ AL+ TP ++
Sbjct: 2608 SPSKDLVSVE-----PVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAA 2662
Query: 298 PLSSSPLATPSPSGTK--ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
P S + T S T+ A P + + T+PP P + L P LQ
Sbjct: 2663 PTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQ 2722
Query: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTI----PPIQVPHSLTSPSL---QAPPSPLA 408
+ T P ++ + + I + V +T+ + Q +
Sbjct: 2723 LV--------GDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPS 2774
Query: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT--SPSRPASTPPDSPPLQAPLSLPAS 466
+ +L T+S+ +P AT + +T AS T + S + + PLQ S A
Sbjct: 2775 IINLSVTSSIVTPVSLATET-VTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAE 2833
Query: 467 PP 468
PP
Sbjct: 2834 PP 2835
Score = 32.0 bits (71), Expect = 3.4
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 11/92 (11%)
Query: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--------QTAS 550
+PQ S I P +T+S L PP+ ++P LP+ AP QT
Sbjct: 3859 APQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPA---LPTQAPTSYTQQSHFEQQTLY 3915
Query: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582
+P+ P A + P TP P+
Sbjct: 3916 HQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ 3947
Score = 30.8 bits (68), Expect = 7.5
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 33/125 (26%)
Query: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP--------PMS 717
S SP + SPP P+ + A +Q+ PSPP SP P+S
Sbjct: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
Query: 718 P-----SATPPPQAPPPLAAPPLQV-----PPSPPASP--------------PMSPSATP 753
P SA P + P P P +V PPASP P+SP+A
Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
Query: 754 PPRVP 758
R P
Sbjct: 3692 SSRAP 3696
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 149 bits (375), Expect = 2e-35
Identities = 238/972 (24%), Positives = 337/972 (34%), Gaps = 222/972 (22%)
Query: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 63 GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
+ G ++ S P + S+ P +P + P + + PGP P + SG
Sbjct: 287 DIVRGESVKPSLP---------SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
T+ PL Q+ PGT P + +
Sbjct: 338 LTK--PLAQQ------------------------------------PGTVKPPV----QP 355
Query: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
GT P A+P P + P + S + S+ +P P A +P G
Sbjct: 356 PGT------TKPPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQPPGVG---------- 398
Query: 243 SSSATPLSSPARSGPSAR--GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
TP P + P + GTP+ A QP GLQ+ P + P K GP
Sbjct: 399 ---KTPAQQPGPAKPPTQQVGTPKPLA--QQP---GLQS--PAKAPGPTKTPVQQPGP-G 447
Query: 301 SSPLATPSPSGTKAR---PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
P P T A+ P PP + P PA PP P P P + PPS Q
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ-- 503
Query: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
P PP Q P+ +P Q P S T PP Q P S PS Q PSP S+ Q+T
Sbjct: 504 PGSTKPPPQQPGPAKPSP--QQPGS--TKPPSQQPGS-AKPSAQ-QPSPAKPSAQQST-- 555
Query: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLSP 475
+P S PLQ P P++ PP Q
Sbjct: 556 ----------------------------KPVSQTGSGKPLQPPTVSPSAKQPPSQ----- 582
Query: 476 AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT--- 532
P TI PL + L H P+ + E Q+++ P LT
Sbjct: 583 -----GLPKTICPLCNTTELLLHVPE---KANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
Query: 533 -------------PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579
L +PS P L+T AP+TT + P P SP
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKT--APVTTTSAVSKSSPQP----QQTSPKKDA 688
Query: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
P+ S A P + PP + P L G PS A PP+A L+ P PS P+
Sbjct: 689 APKQDLSKAPEPKKPPPLVKQPTLHGSPSAK----AKQPPEA-DSLSKPAPPKEPSVPSE 743
Query: 640 PPLSPLATPSPQAPNAL-----AVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPS 693
+P+A P+ P + V A P PS VQ+ +PP+ + PS
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
Query: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP---------LQVPPSPPAS 744
Q+ PP+ P A P P + + + P QV P
Sbjct: 804 QS----------FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 745 PPMSPSA--TPPPRVPPLLAAPPLQVPPSPPASLPM-SPLAKPPPQ-------------- 787
P +P P P+ P P P A + +P P PQ
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 788 -APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
AP + T P + + F G + FS +++L +S P P + AP+ Q P+P
Sbjct: 914 DAPKSQPTTPQETVTGKLFGF-GASIFSQASNL-ISTAGQPGPHSQSGPGAPMKQA-PAP 970
Query: 847 PASPTLQAP-----RRPPTPGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLA 898
PT Q P + PP P V A L P P+ + T P
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPI 1030
Query: 899 GHSSSATSTPEE 910
S S T+ P++
Sbjct: 1031 KDSKSLTAEPQK 1042
Score = 145 bits (365), Expect = 3e-34
Identities = 266/1055 (25%), Positives = 372/1055 (35%), Gaps = 164/1055 (15%)
Query: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAGPT-RSAGT 85
G+ P PA + L R+ +A RA G+ ++P +A + R
Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQEL 87
Query: 86 SSRNP---ASRPPASGRGERAPPAKNTSPGPVSS----PGRASGT-TRPGPLGQKGLRIS 137
S +P + RPP GR + +K+ + S PGR+ T + + L+
Sbjct: 88 DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE 147
Query: 138 AEETVARGKATEAPKRSALSAGARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 191
+ ++ G +E SA+S+ + D + + ++ + E G P
Sbjct: 148 HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET-TKKQKVVQKEQGKPEGI 206
Query: 192 ---------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
P P + + P P + + S+ +P + P G +Q P
Sbjct: 207 IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ 266
Query: 243 SSSAT-PLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTP--PRKDA 292
+ A PL A + RG P+ PS KP Q +PP P +
Sbjct: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 293 APALGPLSSSPLATP--SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
PA P S L P GT PV PP T PP+ PL P A + S
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT-------TKPPAQPLGPAKPPAQQTGSE 379
Query: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAP---PSP 406
PS + P P A +Q P TP Q P+ + P L P LQ+P P P
Sbjct: 380 KPSSEQ-PGPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP 436
Query: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
+ +Q P QA P +T A T P++P S P PA
Sbjct: 437 TK-TPVQQPGPGKIPAQQA-------GPGKTSAQQTGPTKPPSQLPG----------PAK 478
Query: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
PP Q PA P PQ P S+ PP + S PP Q
Sbjct: 479 PPPQQP-GPAKPP--------------------PQQPGSA--KPPSQQPGSTKPPPQQPG 515
Query: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
PA P + S PP Q SA P P P + T P +T S
Sbjct: 516 PAK---PSPQQPGSTKPPSQQPGSAK--------PSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 587 IATPPPQAPPALASPPLQGLPSP--PL---SPLATPPPQAPPXLALPPLQAP-------- 633
PP P+ PP QGLP PL + L P+ Q
Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
Query: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
P+P + L + Q AL L P SP P AP + ++ VS S+ P
Sbjct: 625 PNPHLTEVKEWLCL-NCQMKRALGGDLAPVPSSPQPKLKT-APVTTTSA--VSKSSPQPQ 680
Query: 694 QAPPSLAAPP---LQVPPSPPASPPM--------SPS--ATPPPQAPPPLAAPPLQVPPS 740
Q P A P L P P PP+ SPS A PP+A L+ P PS
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA-DSLSKPAPPKEPS 739
Query: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
P+ +P A P+ P ++ V S + P P +K QA TPPL+
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK-TTPPLKTD 798
Query: 801 PSPPA-SFPGQ----APF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPP-----SPPAS 849
+ P+ SFP +PF S + P S P + QV P P +
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858
Query: 850 PTLQAPRRPPTPGPDTSVS--GPRLTLA-LAPGP---PPPPSRSPSSTLSGPDLAGHSSS 903
T +P+ P P S + GPR T P P P P +S +L+ + S
Sbjct: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
Query: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFRGAPGAPLPWPP 962
+TP+E G + S + A P S+ GP P+ AP P P
Sbjct: 919 QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP---PT 975
Query: 963 ATGPGSADGLCTIYETEG----PESATPAPGALDP 993
+ GP + G + E+ PA L+P
Sbjct: 976 SQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
Score = 142 bits (359), Expect = 1e-33
Identities = 229/915 (25%), Positives = 303/915 (33%), Gaps = 150/915 (16%)
Query: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
+A + A G G P+ +A P G +S SE + + R G
Sbjct: 16 LAAAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71
Query: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---KPKGLQALRPPQVTPPRKDA 292
PA+ S + P G P P P+QP K + R Q P R
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--- 128
Query: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
+P+ L S T K+ +P + L A S + P S S
Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAV---SSVVNKFNPFDLISDSEAS 185
Query: 353 SLQTLPSPPATPPSQAPPS-MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
+T Q P + PP+Q P + IP Q P LQ +P ++SS
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPP-KPIPKQQGPGR---DPLQQDGTPKSISS 241
Query: 412 LQATTSLGSP------------TLQATHSFLTMS-----PRQTQASLTSPS--RPASTPP 452
Q P T Q H+ L + P+ QA + +P+ P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Query: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
PP+Q P P PP Q P S P A S L P
Sbjct: 302 SKPPIQQPT--PGKPPAQ----------------QPGHEKSQPGPAKPPAQPSGLTKPLA 343
Query: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572
+ ++ PP P T PP + L PP QT S ++ P P L P
Sbjct: 344 QQPGTVKPP---VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ------PGPKALAQP 394
Query: 573 PSPLTTPPPETPSSIATPPPQ---APPALASPPLQGLPSPPLSPLATPPP-QAPPXLALP 628
P TP + A PP Q P LA P GL SP +P T P Q P +P
Sbjct: 395 PGVGKTPAQQPGP--AKPPTQQVGTPKPLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIP 450
Query: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
QA P ++ P PS L P PPP P P PP P S
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQ----------LPGPAKPPPQQP--GPAKPPPQQP--GS 496
Query: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
A PPSQ P S PP Q P+ P+ P P +T PP P A P Q P PA P
Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKPS--PQQPGSTKPPSQQPGSAKPSAQQPS--PAKPSAQ 552
Query: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
S P V + PLQ P +SP AK PP PL P
Sbjct: 553 QSTKP---VSQTGSGKPLQPPT-------VSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Query: 809 GQAPFSPSASLPMSPLA----TPPP-------------QAPPVLAAPLLQVPPSP----- 846
+A F+ + + P P Q L L VP SP
Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662
Query: 847 --PASPTLQAPRRPPTPGPDT--SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
P + T + P P + + P+ L+ AP P PP + P L G S
Sbjct: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP-----PLVKQPTLHGSPS 717
Query: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
+ P PE + + P P E P+ S P+A P P P
Sbjct: 718 AKAKQP---------PEADSLSKPAPPKE-----PSVPSEQDKAPVA-DDKPKQPKMVKP 762
Query: 963 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 1022
T S+ T + + P S + P T K + SP ++
Sbjct: 763 TTDLVSSSSATT--KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK- 819
Query: 1023 GELPLGALQASVVQH 1037
+P A + ++ H
Sbjct: 820 -AIPRPASDSKIISH 833
Score = 107 bits (266), Expect = 8e-23
Identities = 201/850 (23%), Positives = 288/850 (33%), Gaps = 170/850 (20%)
Query: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 66 GGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNTSPGPV----SSPG 118
G + P PT+ GT ++ P + PA G P + PG + + PG
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 119 RAS----GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
+ S G T+P P G + K SA + ++ P P P P
Sbjct: 458 KTSAQQTGPTKP-PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Query: 175 AMARRSRAAGTEVGLPRPA---PSAR-PRPPTEGPRKSVSSASEHSTTEP------SPAA 224
A + T+ +P PSA+ P P ++S S+ + +P SP+A
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Query: 225 RRRPSAGGG-------------LQRPASRSLSSSA---TPLSSPARSGPS---------- 258
++ PS G L P + ++ T + S P+
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 259 --------ARGTPRAPAHPSQPKPK----------GLQALRP-PQVTPPRKDAAPALG-- 297
A G AP PS P+PK + P PQ T P+KDAAP
Sbjct: 637 CLNCQMKRALGGDLAPV-PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
Query: 298 ---------PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
PL P SPS KA+ P D+ + P P P P P+A P
Sbjct: 696 KAPEPKKPPPLVKQPTLHGSPSA-KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 349 SAP----PSLQTLPSPPATPPSQAPPS--------MTTPPMQ---APPSLQTIPPIQVPH 393
P P+ + S AT P S TTPP++ A PS P +
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS 814
Query: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
S ++ P S + S +S Q P++ Q + S PD
Sbjct: 815 PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM-------SPKPD 867
Query: 454 SPPLQAPLSLPASP-PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
+ P+ P P P P T+ +P SP Q+ SL + +
Sbjct: 868 AKPM--PKGSPTPPGPRPTAGQTVPTPQQSP-------------KPQEQSRRFSLNLGSI 912
Query: 513 ETQSSLAPPSLQTPPASLTTPPL----ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
AP S T P T L ++ S A + TA P PH ++ P
Sbjct: 913 TD----APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP--GPHSQSGPGAPMKQ 966
Query: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL- 627
AP P T+ P P S PP PA + P + +P L QAP
Sbjct: 967 APAPSQPPTSQGP--PKSTGQAPP--APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 628 -----PPLQAPPSPPASPPLSPLAT-----PSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
PP++ S A P + L T P P++ L L PP+
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
Query: 678 SPPASPPVSPSATP-------------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
+ TP +Q S ++ P P+ P SP P
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
Query: 725 QAPPPLAAPP 734
+ A PP
Sbjct: 1143 SSSQKTAVPP 1152
Score = 82.8 bits (203), Expect = 2e-15
Identities = 160/700 (22%), Positives = 239/700 (34%), Gaps = 92/700 (13%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G+ P P +P+ PGS +PP +A A KP A++
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--SAQQPSPAKPSAQQ-- 553
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
+T P S +G T S + A +PP+ G + P NT+ + P +A+
Sbjct: 554 ----STKPVSQTGSGKPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 124 TRPGPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPS 173
T + TV TE + L+ +R G P P +P
Sbjct: 609 T----------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
Query: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSA 230
P + + V P P P++ +S A E P P PSA
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 231 GGGLQRPASRSLSSSATP----LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQ 284
Q P + SLS A P + S P A P+ P P+ A P
Sbjct: 719 -KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
Query: 285 V------TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
+ + + P L S+ P + P+G K V P D+ A P PA+ S ++
Sbjct: 778 IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK---VSPFDSKAIPRPAS--DSKIIS 832
Query: 339 TPLPLAP----------PSPSAPPSLQT--LPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386
P P + P QT P P A P + P TPP P + QT+
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP---TPPGPRPTAGQTV 889
Query: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT-----HSFLTMSPRQTQASL 441
P P P Q+ L L S+ T Q T F Q +
Sbjct: 890 P---TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 442 TSPSRP---ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
++ +P + + P +P QAP P+ PP TS P S +P P A S
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAP--APSQPP--TSQGPPKSTGQAP----PAPAKSIPVKK 998
Query: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
+AP + + P E P+++ PP+++ SL P A L T
Sbjct: 999 ETKAPAAEKLEPKAE-----QAPTVKRTETEKKPPPIKDSKSLTAEP---QKAVLPTKLE 1050
Query: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP 618
++P + CPL + + P ++ Q P L
Sbjct: 1051 KSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110
Query: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 658
Q L ++ P P+ P SP+ P+ + AV
Sbjct: 1111 TQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
Score = 77.8 bits (190), Expect = 5e-14
Identities = 106/362 (29%), Positives = 134/362 (37%), Gaps = 49/362 (13%)
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGT----PRAPAHPSQPKPKGLQALRPPQVTPP 288
G ++PAS+ S S + S PA+ P R + P P P P PP PP
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP-------PPPPPPP 2420
Query: 289 RKDAAPALGPLSSSPLATPSPSGTKARPV---PPPDNAATPLPAT-------LPPSPPLA 338
P P S P P T A PV P +A T L T LP +
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480
Query: 339 TPLPLAPPSPSAPPS---LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
T P PP PS+ PS P P P + P P P+ I P SL
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPT--DIHPKPTGLSL 2538
Query: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
TS S+ A L + TS SP + + S +T +T PS P TP DS
Sbjct: 2539 TS-SMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP-GTPTDSS 2596
Query: 456 PLQAPLSLPASPPLQ--TSLSPAVS----------PLSSPLTIHPLQALSSLASHSPQAP 503
QA S P P + S+ P S P+SS T + AL + ++ AP
Sbjct: 2597 ASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656
Query: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA----PPPLQTASAPLTTPHLE 559
S P TQ S A+ +T P L S++ P PL L HLE
Sbjct: 2657 SSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL-----ALDNIHLE 2711
Query: 560 TP 561
P
Sbjct: 2712 KP 2713
Score = 71.6 bits (174), Expect = 4e-12
Identities = 71/259 (27%), Positives = 96/259 (37%), Gaps = 25/259 (9%)
Query: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT------PPSQAP---PSLAAPPLQVPPSP 710
L + F PPS + P S S P SQ P PS+++ P + P
Sbjct: 2335 LSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF 2394
Query: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
+S + PPP PPP PP PP PP PP SP T P+ +A+P P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 771 SPPASLPMSPLAKPPPQAPPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
A + A P + T +P P+S P F+ P
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT----------HRPE 2504
Query: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
P PP+ P++ P+ PT P +P +S++ +T A P P SP
Sbjct: 2505 PSKPPIAPKPVIPQLPTTTQKPTDIHP-KPTGLSLTSSMTLNLVTSADYKLPSPTSPLSP 2563
Query: 889 SSTLSGPDLAGHSSSATST 907
S S P S S T T
Sbjct: 2564 HSNKSSPRF---SKSLTET 2579
Score = 61.2 bits (147), Expect = 5e-09
Identities = 91/376 (24%), Positives = 135/376 (35%), Gaps = 57/376 (15%)
Query: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
T+SSL+ PP+S+ P++ L+T + + + P
Sbjct: 2331 TKSSLSETVFDHPPSSVIALPMKE--------------QLSTTYFTSGETFGQ---EKPA 2373
Query: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
S L + P S A P P + Q P PP P PPP PP P
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP--PP---------P 2422
Query: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
P PP PP SP T P+ +A + A +P A + + + + P +
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTA------TPLFDAVTTLETTAVLRSNGLPVT 2476
Query: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
+ APP VPP P + P P + PP+A P V P P + P
Sbjct: 2477 RI--CTTAPP-PVPPKPSSIPSGLVFTHRPEPSKPPIAPKP--VIPQLPTTTQKPTDIHP 2531
Query: 754 PPRVPPLLAAPPLQVPPSPPASL--PMSPLAKPPPQAPPALA-----TPPLQALPSPPAS 806
P L ++ L + S L P SPL+ ++ P + T + LPS P +
Sbjct: 2532 KPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT 2591
Query: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
S S ++ PL +P + L+ V P P + A P +
Sbjct: 2592 ---PTDSSASQAITSWPLGSP--------SKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 867 VSGPRLTLALAPGPPP 882
+SG T + P P
Sbjct: 2641 ISGALQTFSATPVTAP 2656
Score = 59.7 bits (143), Expect = 2e-08
Identities = 109/471 (23%), Positives = 165/471 (35%), Gaps = 79/471 (16%)
Query: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
P V ++++ L + P+ + + + L+A + +T++SL+
Sbjct: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSE--- 2337
Query: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
T D PP + ++LP L T+ +S T + S L S SP +SS
Sbjct: 2338 ---TVFDHPP-SSVIALPMKEQLSTTY------FTSGETFGQEKPASQLPSGSPS--VSS 2385
Query: 507 LIMPPLE-TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565
L P +SS S Q PP PP PPP PP P
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPP--------PPP--------------PPPPPP 2423
Query: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPP---------ALASPPLQGLP-------SP 609
P PL P SP T P+ ++A+P A P A GLP +P
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASP-PLSPLATPSPQAP-------------NA 655
P P+ P P L P PP +P P+ P + Q P ++
Sbjct: 2484 P--PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS 2541
Query: 656 LAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
+ ++L+ + PSP +P S +SP S S T + L P P
Sbjct: 2542 MTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT------ETYVVITLPSEPGTPTDS 2595
Query: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
S + T P P + + V P PP++ P + LQ + P
Sbjct: 2596 SASQAITSWPLGSP--SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPV 2653
Query: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
+ P S A P + + ++ P S S ++P PLA
Sbjct: 2654 TAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLA 2704
Score = 55.5 bits (132), Expect = 3e-07
Identities = 116/521 (22%), Positives = 172/521 (33%), Gaps = 97/521 (18%)
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 220
P P P S + P P P P PP P + + + T
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446
Query: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
SP P + L S+ P++ + P P P PS P GL
Sbjct: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500
Query: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
P+ + P P + L P T P T P P + + + L S P
Sbjct: 2501 HRPEPSKPPIAPKPVIPQL---PTTTQKP--TDIHPKPTGLSLTSSMTLNLVTSADYKLP 2555
Query: 341 LPLAPPSPSAPPS-------------LQTLPSPPATP-PSQAPPSMTTPPMQAP------ 380
P +P SP + S + TLPS P TP S A ++T+ P+ +P
Sbjct: 2556 SPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVS 2615
Query: 381 --PSLQTIPP---IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS----FLT 431
P +PP +++P S S Q AL + AT + QA + FLT
Sbjct: 2616 VEPVFSVVPPVTAVEIPIS----SEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLT 2671
Query: 432 MSPRQTQASLTSPSRPA--------STPP-----DSPPLQAP--------------LSLP 464
+T+ S T + P+ + PP D+ L+ P + L
Sbjct: 2672 TEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLR 2731
Query: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
P ++ + LS+ Q ++ + + I+ T S + P SL
Sbjct: 2732 TVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLA 2791
Query: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
T + T + L A +TT PLQ S PP P
Sbjct: 2792 TETVTFVTCTASASYTTGTESLVGAEHAMTT------------PLQLTTSKHAEPPYRIP 2839
Query: 585 SSIATP--PPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
S P +AP L+ G P+ ++ T P PP
Sbjct: 2840 SDQVFPIAREEAPINLS----LGTPAHAVTLAITKPVTVPP 2876
Score = 42.4 bits (98), Expect = 0.003
Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 56/154 (36%)
Query: 769 PPSPPASLPMSPLA--------------KPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
PPS +LPM KP Q P +P + +LP+ P PF
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG--SPSVSSLPAKPR------PFF 2394
Query: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
S+SL +S A PPP PP PP PP P PP P P
Sbjct: 2395 RSSSLDIS--AQPPPPPPP---------PPPPPPPP-------PPPPPP----------- 2425
Query: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908
P PPP+ + L L S T+TP
Sbjct: 2426 -----PLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 38.9 bits (89), Expect = 0.028
Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 18/160 (11%)
Query: 304 LATPSPSGTKARPVPPPDNAATPLPAT----LPPSPPLATPL---PLAPPSPSAPPSLQT 356
L+ SP K RP P ++ L A L PSPP + + P++P SP
Sbjct: 3581 LSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAF 3640
Query: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
+P P +P + P M P + S++ P P SP A S +A
Sbjct: 3641 VPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK---PLSPTADESSRA-- 3695
Query: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456
Q T + T QT S + + T P+ PP
Sbjct: 3696 -----PFQYTEGYTTKG-SQTMTSSGAQKKVKRTLPNPPP 3729
Score = 34.7 bits (78), Expect = 0.52
Identities = 31/127 (24%), Positives = 46/127 (36%), Gaps = 6/127 (4%)
Query: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP-PPRVPPLLAAPPLQ 767
S SP + +PP P PL++ S + P PP+ P +L +P
Sbjct: 3573 SDTQSPQYLSATSPPKDKKRPT---PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629
Query: 768 VPPSPPASLPMSPLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
+ P P KP P +P + P + +P S S P+SP A
Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTA 3689
Query: 826 TPPPQAP 832
+AP
Sbjct: 3690 DESSRAP 3696
Score = 33.9 bits (76), Expect = 0.89
Identities = 53/179 (29%), Positives = 76/179 (42%), Gaps = 24/179 (13%)
Query: 382 SLQTIPPIQVPH----SLTSPSLQAPPSPLA-----LSSLQATTSLGSPTLQATHSFLTM 432
++QT+ I V ++ +PS++A +S+ + T GS Q T
Sbjct: 3517 AVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQ 3576
Query: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSP--LSSPLT-IH 487
SP+ A TSP + P PL+ S L A +Q + SP SP L SP++ +
Sbjct: 3577 SPQYLSA--TSPPKDKKRPT---PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
Query: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
P +AL S A + PL I P Q L P + PPAS T + P PL
Sbjct: 3632 PGKALES-AFVPYEKPLPDDISP----QKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685
Score = 33.9 bits (76), Expect = 0.89
Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 18/168 (10%)
Query: 351 PPSLQTLPS--PPATPPSQAPPSMTTPPMQAPPSL--------QTIPPIQVPHSLTSPSL 400
PP QT PP +P +Q S P QAP S QT+ QV T P+
Sbjct: 3869 PPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTF 3928
Query: 401 QAPPSPLALSSLQAT-TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
QA + +Q T T S L + + PRQT L P T
Sbjct: 3929 QAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYL----EPKITSNYEVIRNQ 3984
Query: 460 PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507
PL + P+ T + AVS L S L+ S +P+SS+
Sbjct: 3985 PLMI---APVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSI 4029
Score = 32.7 bits (73), Expect = 2.0
Identities = 104/482 (21%), Positives = 154/482 (31%), Gaps = 79/482 (16%)
Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
+A+ P P PP P PPPP P + K A + AT A
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
T + S+ P +R + APP P P S P T RP P
Sbjct: 2462 LETTAVLRSNGLPVTRICTT-----APPP--VPPKPSSIPSGLVFTHRPEP--------- 2505
Query: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGLPR 191
K APK + T PT P P + + + LP
Sbjct: 2506 -------SKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPS 2556
Query: 192 PAPSARPRPPTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
P P PR S S + T PS G +S S + ++ PL
Sbjct: 2557 PTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP---------GTPTDSSASQAITSWPLG 2607
Query: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQ-------------ALRPPQVTPPRKDAAPALG 297
SP++ S P P ++ AL+ TP ++
Sbjct: 2608 SPSKDLVSVE-----PVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAA 2662
Query: 298 PLSSSPLATPSPSGTK--ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
P S + T S T+ A P + + T+PP P + L P LQ
Sbjct: 2663 PTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQ 2722
Query: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTI----PPIQVPHSLTSPSL---QAPPSPLA 408
+ T P ++ + + I + V +T+ + Q +
Sbjct: 2723 LV--------GDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPS 2774
Query: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT--SPSRPASTPPDSPPLQAPLSLPAS 466
+ +L T+S+ +P AT + +T AS T + S + + PLQ S A
Sbjct: 2775 IINLSVTSSIVTPVSLATET-VTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAE 2833
Query: 467 PP 468
PP
Sbjct: 2834 PP 2835
Score = 32.0 bits (71), Expect = 3.4
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 11/92 (11%)
Query: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--------QTAS 550
+PQ S I P +T+S L PP+ ++P LP+ AP QT
Sbjct: 3859 APQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPA---LPTQAPTSYTQQSHFEQQTLY 3915
Query: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582
+P+ P A + P TP P+
Sbjct: 3916 HQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ 3947
Score = 30.8 bits (68), Expect = 7.5
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 33/125 (26%)
Query: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP--------PMS 717
S SP + SPP P+ + A +Q+ PSPP SP P+S
Sbjct: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
Query: 718 P-----SATPPPQAPPPLAAPPLQV-----PPSPPASP--------------PMSPSATP 753
P SA P + P P P +V PPASP P+SP+A
Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
Query: 754 PPRVP 758
R P
Sbjct: 3692 SSRAP 3696
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.127 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,287,167
Number of Sequences: 37866
Number of extensions: 6874105
Number of successful extensions: 280921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2126
Number of HSP's successfully gapped in prelim test: 3621
Number of HSP's that attempted gapping in prelim test: 32005
Number of HSP's gapped (non-prelim): 79985
length of query: 1124
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1011
effective length of database: 13,968,660
effective search space: 14122315260
effective search space used: 14122315260
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.