Guide to the Human Genome
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Search of human proteins with 239751211

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751211 PREDICTED: hypothetical protein XP_002347748 [Homo
sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756716 PREDICTED: hypothetical protein XP_002345022 [Homo ...   427   e-120
gi|239751211 PREDICTED: hypothetical protein XP_002347748 [Homo ...   427   e-120
gi|239745701 PREDICTED: hypothetical protein XP_002343519 [Homo ...   298   2e-81
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]               40   0.001
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    39   0.002
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   38   0.007
gi|55956899 keratin 9 [Homo sapiens]                                   37   0.009
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            37   0.016
gi|119220598 apolipoprotein B48 receptor [Homo sapiens]                36   0.020
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    36   0.027
gi|57864582 hornerin [Homo sapiens]                                    35   0.035
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]           35   0.035
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]          35   0.035
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]          35   0.035
gi|119395750 keratin 1 [Homo sapiens]                                  35   0.045
gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo ...    35   0.059
gi|239750438 PREDICTED: hypothetical protein [Homo sapiens]            35   0.059
gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo ...    35   0.059
gi|4507205 serum response factor (c-fos serum response element-b...    34   0.10 
gi|47132620 keratin 2 [Homo sapiens]                                   34   0.10 
gi|195972866 keratin 10 [Homo sapiens]                                 33   0.13 
gi|239749709 PREDICTED: hypothetical protein [Homo sapiens]            33   0.17 
gi|109255251 loricrin [Homo sapiens]                                   33   0.17 
gi|34486092 adenylate cyclase 5 [Homo sapiens]                         33   0.17 
gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]                33   0.22 
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     33   0.22 
gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho...    33   0.22 
gi|153791670 keratin 76 [Homo sapiens]                                 32   0.29 
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     32   0.29 
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    32   0.29 

>gi|239756716 PREDICTED: hypothetical protein XP_002345022 [Homo
           sapiens]
          Length = 208

 Score =  427 bits (1099), Expect = e-120
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR 60
           MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR
Sbjct: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR 60

Query: 61  AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF 120
           AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF
Sbjct: 61  AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF 120

Query: 121 CVGGVAAGRDWADIFLCALQRSEVLCWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFS 180
           CVGGVAAGRDWADIFLCALQRSEVLCWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFS
Sbjct: 121 CVGGVAAGRDWADIFLCALQRSEVLCWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFS 180

Query: 181 LLFLPSRFLEPLTPGDEEVLARSLLSCV 208
           LLFLPSRFLEPLTPGDEEVLARSLLSCV
Sbjct: 181 LLFLPSRFLEPLTPGDEEVLARSLLSCV 208


>gi|239751211 PREDICTED: hypothetical protein XP_002347748 [Homo
           sapiens]
          Length = 208

 Score =  427 bits (1099), Expect = e-120
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR 60
           MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR
Sbjct: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR 60

Query: 61  AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF 120
           AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF
Sbjct: 61  AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF 120

Query: 121 CVGGVAAGRDWADIFLCALQRSEVLCWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFS 180
           CVGGVAAGRDWADIFLCALQRSEVLCWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFS
Sbjct: 121 CVGGVAAGRDWADIFLCALQRSEVLCWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFS 180

Query: 181 LLFLPSRFLEPLTPGDEEVLARSLLSCV 208
           LLFLPSRFLEPLTPGDEEVLARSLLSCV
Sbjct: 181 LLFLPSRFLEPLTPGDEEVLARSLLSCV 208


>gi|239745701 PREDICTED: hypothetical protein XP_002343519 [Homo
           sapiens]
          Length = 159

 Score =  298 bits (764), Expect = 2e-81
 Identities = 143/143 (100%), Positives = 143/143 (100%)

Query: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR 60
           MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR
Sbjct: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR 60

Query: 61  AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF 120
           AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF
Sbjct: 61  AGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGF 120

Query: 121 CVGGVAAGRDWADIFLCALQRSE 143
           CVGGVAAGRDWADIFLCALQRSE
Sbjct: 121 CVGGVAAGRDWADIFLCALQRSE 143


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 43/121 (35%), Positives = 52/121 (42%), Gaps = 11/121 (9%)

Query: 2    GSRGVQGDP--DGLGGGTGDRGAGSGEAERRDTGLGVGV-----LEGESGEVWESRLALE 54
            G RG QG P   GL G TGDRG   GE   R     VG      +EG  G   ES L  E
Sbjct: 966  GERGFQGKPGLQGLPGSTGDRGL-PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGE 1024

Query: 55   AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGR 114
              G K   G   + GG+ + G+    GA  E      G++ L G PG       +G +G 
Sbjct: 1025 -PGAKGDVGTAGSVGGTGEPGLRGEPGAPGE--EGLQGKDGLKGVPGGRGLPGEDGEKGE 1081

Query: 115  M 115
            M
Sbjct: 1082 M 1082


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 42/146 (28%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 8    GDPDGLGGGTGDR--------GAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGK 59
            G  D  GGG+  R        G+ +G   +   G  +G  +  SG  W    A +A GG 
Sbjct: 1398 GTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADT-ADQASGGS 1456

Query: 60   RAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAA-------LEREGGR 112
            R G +  ++GG+    +    G S     +   EE  W G G  A         ++  GR
Sbjct: 1457 RLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGR 1516

Query: 113  -----GRMIRGGFCVGGV--AAGRDW 131
                 G  I GGF VG V  A G  W
Sbjct: 1517 SWANSGDQISGGFLVGIVDQANGGSW 1542



 Score = 34.7 bits (78), Expect = 0.059
 Identities = 33/99 (33%), Positives = 37/99 (37%), Gaps = 12/99 (12%)

Query: 16   GTGDRGAGSGEAERRDTGLGVGVLEGE----SGEVWE-SRLALEAEGGKRAGGLRDAAGG 70
            G GD+     + E  D   G G   G     SGE W  SR   EA GG R G    A GG
Sbjct: 1741 GPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGG 1800

Query: 71   SQKMGVHIGVG---ASLEFRGSSCGEEPLWGGPGDWAAL 106
            S         G    S E   +    E  W GPG  A +
Sbjct: 1801 SWARSEDQASGRFQVSFEVEAN----EGFWFGPGAEAVI 1835



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 40/138 (28%), Positives = 49/138 (35%), Gaps = 27/138 (19%)

Query: 12   GLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDAAGGS 71
            G   G GD+  G       D   G+G      G+V          GG R G    ++GGS
Sbjct: 1676 GFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVL---------GGARPGPADQSSGGS 1726

Query: 72   ------QKMG-VHIGVG------ASLEFRGSSCGEEPLWGGPGDWAALEREGGR--GRMI 116
                  Q  G   IG G      +  EF   +CG    W G G  A+ E   G   G   
Sbjct: 1727 WAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGS-WAGAGSQASGESWAGSRPGNEA 1785

Query: 117  RGGFCVGG--VAAGRDWA 132
             GG  +G    A G  WA
Sbjct: 1786 IGGSRMGSEDQATGGSWA 1803



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 29/115 (25%), Positives = 40/115 (34%), Gaps = 25/115 (21%)

Query: 21   GAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDAAGGSQKMGVHIGV 80
            G+ +G   +   G   G   G    V      ++  GG    G  D +GG          
Sbjct: 1356 GSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGG---------- 1405

Query: 81   GASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFCVG--GVAAGRDWAD 133
            G+   F   + GE       G WA      G G    GG  +G    ++GR WAD
Sbjct: 1406 GSKPRFEDQASGE-------GSWA------GAGGQASGGSMLGPEDQSSGRSWAD 1447



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 38/153 (24%), Positives = 54/153 (35%), Gaps = 27/153 (17%)

Query: 5    GVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEG-ESGE-VW---------ESRLAL 53
            G +       G   + GAG+G     + G G G   G ESG  VW         ESRL  
Sbjct: 1900 GAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGA 1959

Query: 54   EAEGGKRAGGL----------RDAAGGSQKMGVHIGVGASLE----FRGSSCGEEPLWGG 99
              E G  +  L          R+++   +++ +     A  E    FR  S  +     G
Sbjct: 1960 GEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWAESENSNTFRSKSGKDASFESG 2019

Query: 100  PGDWAALER--EGGRGRMIRGGFCVGGVAAGRD 130
             GD  +++   E   G  I   FC G      D
Sbjct: 2020 AGDNTSIKDKFEAAGGVDIGSWFCAGNENTSED 2052


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 1   MGSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGL-GVGVLEGESGEVWESRLALEAEGGK 59
           MG  G+ G P GL G  GDRG G     + D G+ G   L G+ GE+  S L     G K
Sbjct: 411 MGDPGLPG-PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLV----GPK 465

Query: 60  RAGGLRDAAGGSQKMG 75
              G R   G     G
Sbjct: 466 GESGSRGELGPKGTQG 481


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 41/127 (32%), Positives = 49/127 (38%), Gaps = 23/127 (18%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRA 61
           GS G  G   G GGG+G RG GSG +    +G G G   G  G            GG  +
Sbjct: 495 GSYGGGGSGGGYGGGSGSRG-GSGGSYGGGSGSGGGSGGGYGG----------GSGGGHS 543

Query: 62  GGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFC 121
           GG     G S   G + G G+     GS  G    +GG          GG G    GG  
Sbjct: 544 GG--SGGGHSGGSGGNYGGGS-----GSGGGSGGGYGGGSG-----SRGGSGGSHGGGSG 591

Query: 122 VGGVAAG 128
            GG + G
Sbjct: 592 FGGESGG 598


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 36.6 bits (83), Expect = 0.016
 Identities = 39/114 (34%), Positives = 45/114 (39%), Gaps = 24/114 (21%)

Query: 2   GSRGVQGDPDGL------GGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEA 55
           GS G +  P G       GGG  DRG    EAE R T    G  E E G           
Sbjct: 43  GSEGAEEAPRGAAAVKEAGGGGPDRGP---EAEARGTRGAHGETEAEEGA---------P 90

Query: 56  EGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALERE 109
           EG +   G  + +G  Q  G   G GA  E RG +  E      P D AA ER+
Sbjct: 91  EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQRE------PEDSAAPERQ 138


>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
          Length = 1088

 Score = 36.2 bits (82), Expect = 0.020
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 8   GDPDGLGGGTGDRGAG--SGEAERRDTGLGVG-VLEGESGEVWESRLALEAEGGKRAGGL 64
           G PD     TG   AG   G+     +  G G  LEG  G+ W+S+   EA  G+ AGG 
Sbjct: 739 GLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQ 798

Query: 65  RDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGG 99
                GS +  V  G G+ +E   S  G    WGG
Sbjct: 799 EFGLEGSAEEEV-TGRGSQVEAFESREGGP--WGG 830


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 35.8 bits (81), Expect = 0.027
 Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 7/110 (6%)

Query: 4   RGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGG 63
           +G +   +G G   G+ G G GE E    G G G  EGE     E       E G+  G 
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEE---GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE 913

Query: 64  LRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGG---PGDWAALEREG 110
             +  G  ++ G   G G   E  G   GE+    G    G+W   E EG
Sbjct: 914 EEEGEGKGEEEGEE-GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962



 Score = 34.7 bits (78), Expect = 0.059
 Identities = 34/103 (33%), Positives = 40/103 (38%), Gaps = 11/103 (10%)

Query: 16  GTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAG---GLRDAAGGSQ 72
           G G+   G GE E    G G G  EGE GE  E     E EG +  G   G  +  G  +
Sbjct: 840 GEGEEEEGEGEEEE---GEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896

Query: 73  K-----MGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREG 110
           +      G   G G   E  G   GEE    G G+    E EG
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 34/116 (29%), Positives = 43/116 (37%), Gaps = 12/116 (10%)

Query: 7   QGDPDGLGGGTGDRGAGSGEAE-------RRDTGLGVGVLEGESGEVWESRLALEAEGGK 59
           +G+ +  G G G+   G GE E         + G G G  EGE GE        E EG  
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943

Query: 60  RAGGLRDAAG---GSQKMGVHIG--VGASLEFRGSSCGEEPLWGGPGDWAALEREG 110
             G   +  G   G ++ G   G   G      G   GEE    G G+    E EG
Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 2/91 (2%)

Query: 5    GVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGE-VWESRLALEAEGGKRAGG 63
            G + + +G G   G+ G G GE E  +     G  EGE  E  WE     E EG     G
Sbjct: 912  GEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE-EEEGEGEGEEEG 970

Query: 64   LRDAAGGSQKMGVHIGVGASLEFRGSSCGEE 94
              +   G  +     G G   E  G   GEE
Sbjct: 971  EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 32/99 (32%), Positives = 40/99 (40%), Gaps = 17/99 (17%)

Query: 5    GVQGDPDGL---GGGTGDRGAGSGEAE------RRDTGLGVGVLEGESGEVWESRLALEA 55
            G +G+ +G    G G G+ G G GE E        + G G G  EGE GE  E     E 
Sbjct: 925  GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGE-GEGEEG----EG 979

Query: 56   EGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEE 94
            EG +  G         ++ G   G G   E  G   GEE
Sbjct: 980  EGEEEEGEGEGEEEEGEEEGEEEGEG---EEEGEGEGEE 1015



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 3/61 (4%)

Query: 5    GVQGDPDGL---GGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRA 61
            G +G+ +G    G G G+   G  E E    G   G  EGE  E  E    +E E G+  
Sbjct: 974  GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033

Query: 62   G 62
            G
Sbjct: 1034 G 1034


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 35.4 bits (80), Expect = 0.035
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 10/108 (9%)

Query: 4   RGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGE--SGEVWESRLALEAEGG 58
           RG  G   G   G G RG+GSG++    R  +G G     G   SG    S    ++  G
Sbjct: 880 RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSG 939

Query: 59  KRAGGLRDAAGGS-----QKMGVHIGVGASLEFRGSSCGEEPLWGGPG 101
           + +G  +  +G       ++ G   G  +  E  GSS G    +G  G
Sbjct: 940 QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHG 987



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 5/116 (4%)

Query: 3   SRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAG 62
           SRG  G   G     G  G+GSG +         G + G+S        + ++ G  + G
Sbjct: 661 SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPH---GSVSGQSSGFGHKSGSGQSSGYSQHG 717

Query: 63  GLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRG 118
                + G +K G   G  +  E  GSS G    +G  G  +   +  G GR   G
Sbjct: 718 SGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG--SGSHQSSGHGRQGSG 771



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 29/109 (26%), Positives = 40/109 (36%), Gaps = 11/109 (10%)

Query: 4   RGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGE--SGEVWESRLALEAEGG 58
           RG      G   G G RG+GSG++    +  TG G     G   SG  + S         
Sbjct: 413 RGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSS 472

Query: 59  KRAGGLRDAAGGS------QKMGVHIGVGASLEFRGSSCGEEPLWGGPG 101
           + + G      GS       + G   G  +  E +GSS G    +G  G
Sbjct: 473 EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHG 521



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 32/132 (24%), Positives = 51/132 (38%), Gaps = 24/132 (18%)

Query: 5    GVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGE---------VWESRLA 52
            G  G       G G +G+GSG++    R  +GLG     G+ G           +ESRL 
Sbjct: 2630 GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLG 2689

Query: 53   LEAEGGKRAGGLRDAAGGSQ------------KMGVHIGVGASLEFRGSSCGEEPLWGGP 100
              +  G+   G   ++  SQ            + G   G  ++ +  GSS G+   +G  
Sbjct: 2690 HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHR 2749

Query: 101  GDWAALEREGGR 112
            G  ++     GR
Sbjct: 2750 GSGSSQSSGYGR 2761



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 11/102 (10%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGE--SGEVWESRLALEAEG 57
            S G +G       G G  GAGSG++    R  +G G     G+  SG  W S       G
Sbjct: 1335 SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394

Query: 58   GKRAGGLRD------AAGGSQKMGVHIGVGASLEFRGSSCGE 93
              ++ G          + G  + G   G  +S E  GS  G+
Sbjct: 1395 SGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 4/110 (3%)

Query: 4   RGVQGDPDGLGGGTGDRGAGSGEAERRDT-GLGVGVLEGESGEVWESRLALEAEGGKRAG 62
           RG  G   G     G  G+GSG++   DT G G G   G S     S    ++ G  + G
Sbjct: 192 RGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSG---QSSGYSQHG 248

Query: 63  GLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGR 112
                + G  + G   G  +  E   SS G    +G  G  +      GR
Sbjct: 249 SGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGR 298



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/125 (25%), Positives = 47/125 (37%), Gaps = 13/125 (10%)

Query: 5    GVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGEVWESRLAL---EAEGG 58
            G QG   G   G G RG+GS ++    R  +G G     G+ G            E+  G
Sbjct: 1116 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175

Query: 59   KRAGGLRDAAG-----GSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRG 113
            + +   +  +G     G  + G   G  +  E  GSS G    +G  G  +   +  G G
Sbjct: 1176 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG--SGSRQSSGHG 1233

Query: 114  RMIRG 118
            R   G
Sbjct: 1234 RQGSG 1238



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 11/102 (10%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGE--SGEVWESRLALEAEG 57
            S G  G         G +G+GSG++    R  +G G     G+  SG  W S       G
Sbjct: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864

Query: 58   GKRAGGLRD------AAGGSQKMGVHIGVGASLEFRGSSCGE 93
              ++ G          + G  + G   G  +S E  GS  G+
Sbjct: 1865 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 1906



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/125 (25%), Positives = 47/125 (37%), Gaps = 13/125 (10%)

Query: 5    GVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGEVWESRLAL---EAEGG 58
            G QG   G   G G RG+GS ++    R  +G G     G+ G            E+  G
Sbjct: 2056 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115

Query: 59   KRAGGLRDAAG-----GSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRG 113
            + +   +  +G     G  + G   G  +  E  GSS G    +G  G  +   +  G G
Sbjct: 2116 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG--SGSRQSSGHG 2173

Query: 114  RMIRG 118
            R   G
Sbjct: 2174 RQGSG 2178



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 11/102 (10%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGE--SGEVWESRLALEAEG 57
            S G  G         G +G+GSG++    R  +G G     G+  SG  W S       G
Sbjct: 2275 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334

Query: 58   GKRAGGLRD------AAGGSQKMGVHIGVGASLEFRGSSCGE 93
              ++ G          + G  + G   G  +S E  GS  G+
Sbjct: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/125 (25%), Positives = 47/125 (37%), Gaps = 13/125 (10%)

Query: 5    GVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGEVWESRLAL---EAEGG 58
            G QG   G   G G RG+GS ++    R  +G G     G+ G            E+  G
Sbjct: 2526 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585

Query: 59   KRAGGLRDAAG-----GSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRG 113
            + +   +  +G     G  + G   G  +  E  GSS G    +G  G  +   +  G G
Sbjct: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG--SGSRQSSGHG 2643

Query: 114  RMIRG 118
            R   G
Sbjct: 2644 RQGSG 2648



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 31/127 (24%), Positives = 43/127 (33%), Gaps = 12/127 (9%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAG 62
            SRG  G   G     G  G+GSG +  R           ESG    S L        ++ 
Sbjct: 1950 SRGRHGSGSGQSSSYGPYGSGSGWSSSRG--------PYESGSGHSSGLGHRESRSGQSS 2001

Query: 63   GLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFCV 122
            G       S     H G   S   + SSCG+    G     ++   + G G     G+  
Sbjct: 2002 GYGQHGSSSGHSSTH-GQHGSASGQSSSCGQH---GASSGQSSSHGQHGSGSSQSSGYGR 2057

Query: 123  GGVAAGR 129
             G  +G+
Sbjct: 2058 QGSGSGQ 2064



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 29/116 (25%), Positives = 40/116 (34%), Gaps = 14/116 (12%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAG 62
            SRG  G   G     G  G+GSG +  R      G  E  SG    S       G   + 
Sbjct: 1244 SRGRHGSGLGHSSSHGQHGSGSGRSSSR------GPYESRSGH--SSVFGQHESGSGHSS 1295

Query: 63   GLRDAAGGS------QKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGR 112
                   GS       + G   G  ++ +  GSS G+   +G  G  ++     GR
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGR 1351



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 29/116 (25%), Positives = 43/116 (37%), Gaps = 14/116 (12%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGEVWESRLALEAEGGK 59
            S G  G       G G +G+GSG++    +R +G       G  G    S     +  G+
Sbjct: 1101 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQ 1156

Query: 60   RAGGLRDAAGGSQKMGVH---IGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGR 112
               GL +++G     G H    G  +S    GS  G    +G  G  +     G R
Sbjct: 1157 HGSGLGESSG----FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 29/116 (25%), Positives = 43/116 (37%), Gaps = 14/116 (12%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGEVWESRLALEAEGGK 59
            S G  G       G G +G+GSG++    +R +G       G  G    S     +  G+
Sbjct: 1571 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQ 1626

Query: 60   RAGGLRDAAGGSQKMGVH---IGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGR 112
               GL +++G     G H    G  +S    GS  G    +G  G  +     G R
Sbjct: 1627 HGSGLGESSG----FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 29/116 (25%), Positives = 43/116 (37%), Gaps = 14/116 (12%)

Query: 3    SRGVQGDPDGLGGGTGDRGAGSGEAE---RRDTGLGVGVLEGESGEVWESRLALEAEGGK 59
            S G  G       G G +G+GSG++    +R +G       G  G    S     +  G+
Sbjct: 2511 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQ 2566

Query: 60   RAGGLRDAAGGSQKMGVH---IGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGR 112
               GL +++G     G H    G  +S    GS  G    +G  G  +     G R
Sbjct: 2567 HGSGLGESSG----FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2618


>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
          Length = 571

 Score = 35.4 bits (80), Expect = 0.035
 Identities = 45/165 (27%), Positives = 58/165 (35%), Gaps = 28/165 (16%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALE------- 54
           G  GV G   G+GGG  DR +G   A  R +    G L G  G +    LA+        
Sbjct: 34  GGVGVGGGGTGVGGGDRDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGP 93

Query: 55  --------------AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGP 100
                           GG     L  AA G    GV +GVG ++   G  C       GP
Sbjct: 94  RPQQASPPPCGGPGGPGGGPGDALGAAAAGVGAAGVVVGVGGAVGV-GGCC------SGP 146

Query: 101 GDWAALEREGGRGRMIRGGFCVGGVAAGRDWADIFLCALQRSEVL 145
           G      +  G G +  G      V AG +  D +  A  R E +
Sbjct: 147 GHSKRRRQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAARIEAM 191


>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 35.4 bits (80), Expect = 0.035
 Identities = 45/165 (27%), Positives = 58/165 (35%), Gaps = 28/165 (16%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALE------- 54
           G  GV G   G+GGG  DR +G   A  R +    G L G  G +    LA+        
Sbjct: 34  GGVGVGGGGTGVGGGDRDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGP 93

Query: 55  --------------AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGP 100
                           GG     L  AA G    GV +GVG ++   G  C       GP
Sbjct: 94  RPQQASPPPCGGPGGPGGGPGDALGAAAAGVGAAGVVVGVGGAVGV-GGCC------SGP 146

Query: 101 GDWAALEREGGRGRMIRGGFCVGGVAAGRDWADIFLCALQRSEVL 145
           G      +  G G +  G      V AG +  D +  A  R E +
Sbjct: 147 GHSKRRRQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAARIEAM 191


>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 35.4 bits (80), Expect = 0.035
 Identities = 45/165 (27%), Positives = 58/165 (35%), Gaps = 28/165 (16%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALE------- 54
           G  GV G   G+GGG  DR +G   A  R +    G L G  G +    LA+        
Sbjct: 34  GGVGVGGGGTGVGGGDRDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGP 93

Query: 55  --------------AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGP 100
                           GG     L  AA G    GV +GVG ++   G  C       GP
Sbjct: 94  RPQQASPPPCGGPGGPGGGPGDALGAAAAGVGAAGVVVGVGGAVGV-GGCC------SGP 146

Query: 101 GDWAALEREGGRGRMIRGGFCVGGVAAGRDWADIFLCALQRSEVL 145
           G      +  G G +  G      V AG +  D +  A  R E +
Sbjct: 147 GHSKRRRQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAARIEAM 191


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 35.0 bits (79), Expect = 0.045
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 19/98 (19%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRA 61
           GS G  G   G GGG+   G G G      +G   G   G SG            GG  +
Sbjct: 550 GSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSG-----------GGGGGS 598

Query: 62  GGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGG 99
            G R + GGS         G S+  RGSS G     GG
Sbjct: 599 SGGRGSGGGSS--------GGSIGGRGSSSGGVKSSGG 628



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 39/126 (30%), Positives = 42/126 (33%), Gaps = 22/126 (17%)

Query: 3   SRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAG 62
           S G  G     GGG G  GAG G   R    LG            +S     A GG R  
Sbjct: 39  SGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGS----------KSISISVARGGGRGS 88

Query: 63  GLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFCV 122
           G     GG    G   G G    F G   G     GG G + +     G G    GGF  
Sbjct: 89  GFGGGYGGGGFGGGGFGGGG---FGGGGIG----GGGFGGFGS-----GGGGFGGGGFGG 136

Query: 123 GGVAAG 128
           GG   G
Sbjct: 137 GGYGGG 142



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 27/128 (21%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRA 61
           GSRG  G   G GG +   G GS       +G G G   G  G    S            
Sbjct: 516 GSRGGGGGGYGSGGSSYGSGGGS-----YGSGGGGGGGRGSYGSGGSSY--------GSG 562

Query: 62  GGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFC 121
           GG   + GG    G +    +S  +RG S G     GG G        GGRG    GG  
Sbjct: 563 GGSYGSGGGGGGHGSYGSGSSSGGYRGGSGG-----GGGGS------SGGRG---SGGGS 608

Query: 122 VGGVAAGR 129
            GG   GR
Sbjct: 609 SGGSIGGR 616


>gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo
           sapiens]
          Length = 600

 Score = 34.7 bits (78), Expect = 0.059
 Identities = 35/120 (29%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAE-------RRDTGLGVGVLEGESGEVWESRLALE 54
           G  G QG    + G  G R  G G  E       R   G+G        G   E  +A+ 
Sbjct: 273 GRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVH 332

Query: 55  AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGR 114
             GG R GG R           H+ VG  +  + S  G     GG      +E +GGRGR
Sbjct: 333 RAGGCRRGGGRRCG--------HVRVG--VREQASERGHGQALGGQDVLLEVEGQGGRGR 382


>gi|239750438 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 510

 Score = 34.7 bits (78), Expect = 0.059
 Identities = 35/120 (29%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAE-------RRDTGLGVGVLEGESGEVWESRLALE 54
           G  G QG    + G  G R  G G  E       R   G+G        G   E  +A+ 
Sbjct: 130 GRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVH 189

Query: 55  AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGR 114
             GG R GG R           H+ VG  +  + S  G     GG      +E +GGRGR
Sbjct: 190 RAGGCRRGGGRRCG--------HVRVG--VREQASERGHGQALGGQDVLLEVEGQGGRGR 239


>gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo
           sapiens]
          Length = 457

 Score = 34.7 bits (78), Expect = 0.059
 Identities = 35/120 (29%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAE-------RRDTGLGVGVLEGESGEVWESRLALE 54
           G  G QG    + G  G R  G G  E       R   G+G        G   E  +A+ 
Sbjct: 130 GRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVH 189

Query: 55  AEGGKRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGR 114
             GG R GG R           H+ VG  +  + S  G     GG      +E +GGRGR
Sbjct: 190 RAGGCRRGGGRRCG--------HVRVG--VREQASERGHGQALGGQDVLLEVEGQGGRGR 239


>gi|4507205 serum response factor (c-fos serum response
           element-binding transcription factor) [Homo sapiens]
          Length = 508

 Score = 33.9 bits (76), Expect = 0.10
 Identities = 32/103 (31%), Positives = 38/103 (36%), Gaps = 11/103 (10%)

Query: 14  GGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDAAGGSQK 73
           GGG G RGA  G       GLG G LE E+        A        AG L   + G  +
Sbjct: 31  GGGGGTRGANGGRVPGNGAGLGPGRLEREAA------AAAATTPAPTAGALYSGSEGDSE 84

Query: 74  MGVHIGVGASLEFRGSSCGEEPLW---GGPGDWAALEREGGRG 113
            G    +GA       S  E  +    GGP   A+    GG G
Sbjct: 85  SGEEEELGAERRGLKRSLSEMEIGMVVGGPE--ASAAATGGYG 125


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 33.9 bits (76), Expect = 0.10
 Identities = 35/111 (31%), Positives = 42/111 (37%), Gaps = 20/111 (18%)

Query: 14  GGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDAAGGSQK 73
           GGG G RG  SG A          V+ G S     S   L   GG   GG      GS+ 
Sbjct: 14  GGGGGFRGFSSGSA----------VVSGGSRRSTSSFSCLSRHGGG-GGGFGGGGFGSRS 62

Query: 74  MGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFCVGG 124
           +   +G+G +     S  G      G G + A    GGRG    GG   GG
Sbjct: 63  L---VGLGGTKSISISVAG------GGGGFGAAGGFGGRGGGFGGGSSFGG 104



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 27/89 (30%), Positives = 32/89 (35%), Gaps = 9/89 (10%)

Query: 2   GSRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRA 61
           GSRG  G    + GG    G GSG       G   G + G             + GGK +
Sbjct: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGG---------GYGSGGGKHS 597

Query: 62  GGLRDAAGGSQKMGVHIGVGASLEFRGSS 90
            G     G S   G   G G S   +GSS
Sbjct: 598 SGGGSRGGSSSGGGYGSGGGGSSSVKGSS 626



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 32/114 (28%), Positives = 38/114 (33%), Gaps = 26/114 (22%)

Query: 15  GGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDAAGGSQKM 74
           GG+G RG+ SG           G   G S             GG+++G    + GG    
Sbjct: 519 GGSGGRGSSSGG----------GYSSGSSSY---------GSGGRQSGSRGGSGGGGSIS 559

Query: 75  GVHIGVGASLEFR----GSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFCVGG 124
           G   G G     R    G S G     GG G        GG     RGG   GG
Sbjct: 560 GGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS---RGGSSSGG 610


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 39/126 (30%), Positives = 43/126 (34%), Gaps = 25/126 (19%)

Query: 2   GSRGVQGDPDGLGGGT---GDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGG 58
           G RG      G GGG+   G  G G G      +G G G   G SG            GG
Sbjct: 462 GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYG--GGSSG------------GG 507

Query: 59  KRAGGLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRG 118
              GG     GG    G H G  +     GSS G    +GG          GG G    G
Sbjct: 508 SSGGGY----GGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYG----G 559

Query: 119 GFCVGG 124
           G   GG
Sbjct: 560 GSSSGG 565


>gi|239749709 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 178

 Score = 33.1 bits (74), Expect = 0.17
 Identities = 25/78 (32%), Positives = 27/78 (34%), Gaps = 3/78 (3%)

Query: 8  GDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDA 67
          G+     GG G  G G      R  G G  V  G    VW SR    AEGG         
Sbjct: 2  GEASSAPGGRGRSGLGGSGGAPRVRGRGTAVGVGIGVRVWRSR---RAEGGGAEAAAART 58

Query: 68 AGGSQKMGVHIGVGASLE 85
          AGG  +     G  A  E
Sbjct: 59 AGGEPRAQRQAGSQADEE 76


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 33.1 bits (74), Expect = 0.17
 Identities = 35/127 (27%), Positives = 43/127 (33%), Gaps = 7/127 (5%)

Query: 5   GVQGDPDGLGGGTGDRGAG-SGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGG 63
           G  G   G  GG G  G G  G +     G G+G   G SG      +     GG   GG
Sbjct: 45  GSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSG----GSVKYSGGGGSSGGG 100

Query: 64  LRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRGRMIRGGFC-- 121
               + G    G     G      GS C      G  G  +     GG G   +   C  
Sbjct: 101 SGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQS 160

Query: 122 VGGVAAG 128
            GGV++G
Sbjct: 161 YGGVSSG 167



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 33/140 (23%), Positives = 45/140 (32%), Gaps = 31/140 (22%)

Query: 15  GGTGDRGAGSG---EAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLR------ 65
           GG G  G GSG         +G G G      G      +  ++ GG  +GG        
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176

Query: 66  -----------------DAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALER 108
                               GG    G   G  +S +   +SC  +P +GG         
Sbjct: 177 FSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG--G 234

Query: 109 EGGRGRMIRGGFCVGGVAAG 128
            GG G    GG   GG ++G
Sbjct: 235 SGGSGCFSSGG---GGGSSG 251



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 17/117 (14%)

Query: 12  GLGGGT--GDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAE--------GGKRA 61
           G GGG+  G  G GSG       G G G +  +  +V ++  A +          GG   
Sbjct: 180 GGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQ--QVTQTSCAPQPSYGGGSSGGGGSGG 237

Query: 62  GGLRDAAGGSQKMGVH-----IGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRG 113
            G   + GG    G       IG G  +   GS CG     GG G  +      G+G
Sbjct: 238 SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294


>gi|34486092 adenylate cyclase 5 [Homo sapiens]
          Length = 1261

 Score = 33.1 bits (74), Expect = 0.17
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 10  PDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAGGLRDAAG 69
           P G GGG+    A +G  E R   + VG+ E       + R A E E G   GG     G
Sbjct: 132 PAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRG----KGRAADELEAGAVEGGEGSGDG 187

Query: 70  GSQ-KMGVHIGVGASLEFRGSSC 91
           GS    G   G GA L   G+ C
Sbjct: 188 GSSADSGSGAGPGAVLSL-GACC 209


>gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
          Length = 462

 Score = 32.7 bits (73), Expect = 0.22
 Identities = 40/149 (26%), Positives = 48/149 (32%), Gaps = 34/149 (22%)

Query: 25  GEAERRDTGLGVGVLEGESG---------EVWESRLALEAE--------GGKRAGGLRDA 67
           G +   + GLG     GE+G         E  ES  A E          GG+R  G    
Sbjct: 255 GASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGG 314

Query: 68  AGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRG--------RMIRGG 119
           AGG+   G   G   S     S          PG    L R   R         R  R  
Sbjct: 315 AGGADGQGAGPGAAESGALTASR--------SPGPGGRLSRASSRSVEFFLSRRRRARSS 366

Query: 120 FCVGGVAAGRDWADIFLCALQRSE-VLCW 147
            C   VA  R+    F+ A+     VLCW
Sbjct: 367 VCRRKVAQAREKRFTFVLAVVMGVFVLCW 395


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 32.7 bits (73), Expect = 0.22
 Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 6/85 (7%)

Query: 56  EGGKRAGGLRDAAGGSQKM--GVHIGVGASLEFRGSSCGEEPLWGGPGDWAALEREGGRG 113
           E G   GG     GG      GV++   A L +   SCG  P  GG  + AA    GG G
Sbjct: 41  EAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFPTLGGKRNEAASPGSGGGG 100

Query: 114 RMIRGGFCVGGVAAGRDWADIFLCA 138
               GG   G    G    D++L A
Sbjct: 101 ----GGLGPGAHGYGPSPIDLWLDA 121


>gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo
           sapiens]
          Length = 1288

 Score = 32.7 bits (73), Expect = 0.22
 Identities = 17/55 (30%), Positives = 25/55 (45%)

Query: 146 CWSHPLRRREGKRKTLSAPQGGSSLRTLPFRIIFSLLFLPSRFLEPLTPGDEEVL 200
           CW  PL     + + L+AP G    R+ P  +++ L   P   LEP    + E L
Sbjct: 16  CWQDPLAVALSRGRQLAAPPGRGCARSRPLSVVYVLTREPQPGLEPREGTEAEPL 70


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 32.3 bits (72), Expect = 0.29
 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 8/99 (8%)

Query: 3   SRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKRAG 62
           SRGV G   G G G    G   G +    +G GV    G SG  +   ++  + GG+ + 
Sbjct: 522 SRGVFGGVSGSGSG----GYKGGSSSSSSSGYGVS---GGSGSGYGG-VSSGSTGGRGSS 573

Query: 63  GLRDAAGGSQKMGVHIGVGASLEFRGSSCGEEPLWGGPG 101
           G   ++    ++G    +  S    GSS G     GG G
Sbjct: 574 GSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSG 612



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 38/129 (29%), Positives = 46/129 (35%), Gaps = 15/129 (11%)

Query: 3   SRGVQGDPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGEVWESRLALEAEGGKR-- 60
           S G  G   G   G G  G+ S      +  + + V  G S             GG R  
Sbjct: 36  SGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAAGSS--------RAGGFGGGRSS 87

Query: 61  ---AGGLRDAAGGSQKMGVHIGVGASLEFRGSS-CGEEPLWGGPGDWAALEREGGRGRMI 116
              AGG     GGS   G   G G    F G+   G    +GGPG +      GG G   
Sbjct: 88  CGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGVFGGPGSFGGPGGFG 147

Query: 117 RGGFCVGGV 125
            GGF  GG+
Sbjct: 148 PGGF-PGGI 155


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 32.3 bits (72), Expect = 0.29
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 2    GSRGVQG--DPDGLGGGTGDRGAGSGEAERRDTGLGVGVLEGESGE 45
            G +GV G   P G  G  GD+GA   + +    G+G+  L GE G+
Sbjct: 1023 GEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGD 1068


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 32.3 bits (72), Expect = 0.29
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 5/82 (6%)

Query: 8   GDPDGLGGGTGDRGAGSGEAER-----RDTGLGVGVLEGESGEVWESRLALEAEGGKRAG 62
           G   G  GG    GAG+G + R     R   L +G L+    +   SR  L A     AG
Sbjct: 725 GPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAG 784

Query: 63  GLRDAAGGSQKMGVHIGVGASL 84
           G     GG++  GV  G  A+L
Sbjct: 785 GSGGGPGGAEGGGVTGGARAAL 806


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.141    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,735,047
Number of Sequences: 37866
Number of extensions: 519945
Number of successful extensions: 2793
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 2266
Number of HSP's gapped (non-prelim): 526
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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