BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239749482 PREDICTED: hypothetical protein [Homo sapiens] (195 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239749482 PREDICTED: hypothetical protein [Homo sapiens] 399 e-111 gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] 376 e-105 gi|239754940 PREDICTED: hypothetical protein [Homo sapiens] 272 1e-73 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 67 7e-12 gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 2e-11 gi|7706501 WW domain binding protein 11 [Homo sapiens] 62 4e-10 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 60 9e-10 gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 58 6e-09 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 57 8e-09 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 57 1e-08 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 57 1e-08 gi|33356148 formin-like 1 [Homo sapiens] 57 1e-08 gi|56549694 enabled homolog isoform a [Homo sapiens] 57 1e-08 gi|39930375 enabled homolog isoform b [Homo sapiens] 57 1e-08 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 57 1e-08 gi|7662302 TBK1 binding protein 1 [Homo sapiens] 56 2e-08 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 3e-08 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 3e-08 gi|33286436 gametogenetin [Homo sapiens] 55 3e-08 gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 4e-08 gi|22027541 programmed cell death 7 [Homo sapiens] 55 4e-08 gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 54 8e-08 gi|11386183 WAS protein family, member 2 [Homo sapiens] 54 1e-07 gi|157168329 formin 1 [Homo sapiens] 53 1e-07 gi|160707881 formin 2 [Homo sapiens] 53 1e-07 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 53 2e-07 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 53 2e-07 gi|153792074 proline rich 12 [Homo sapiens] 53 2e-07 gi|171906567 peripheral benzodiazepine receptor-associated prote... 52 3e-07 gi|171906559 peripheral benzodiazepine receptor-associated prote... 52 3e-07 >gi|239749482 PREDICTED: hypothetical protein [Homo sapiens] Length = 195 Score = 399 bits (1024), Expect = e-111 Identities = 195/195 (100%), Positives = 195/195 (100%) Query: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP Sbjct: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR Sbjct: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180 Query: 181 LGPVHAGSDLELRLA 195 LGPVHAGSDLELRLA Sbjct: 181 LGPVHAGSDLELRLA 195 >gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 376 bits (966), Expect = e-105 Identities = 183/183 (100%), Positives = 183/183 (100%) Query: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP Sbjct: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR Sbjct: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180 Query: 181 LGP 183 LGP Sbjct: 181 LGP 183 >gi|239754940 PREDICTED: hypothetical protein [Homo sapiens] Length = 159 Score = 272 bits (696), Expect = 1e-73 Identities = 138/162 (85%), Positives = 140/162 (86%), Gaps = 4/162 (2%) Query: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP Sbjct: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR Sbjct: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 PSSPPP P P P S+L AP PP P S+ A Sbjct: 121 PSSPPPSPPSPPVP----TAQSSLPAPWPPQGPRSPAPSLRA 158 Score = 30.4 bits (67), Expect = 1.00 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 22/113 (19%) Query: 76 QPRRRSPGPQGGGGG-----DIASP----LP-PALQPRGAPAVPAAPSPGPLPARPSSPP 125 Q R +GGG G + P LP PAL G + P P A P +P Sbjct: 6 QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGI----RPAPAAAHPPAPR 61 Query: 126 PRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178 RP+ SALAA +P P PQG P + + GAP Sbjct: 62 ERPAAAR--------LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 67.4 bits (163), Expect = 7e-12 Identities = 57/156 (36%), Positives = 71/156 (45%), Gaps = 27/156 (17%) Query: 48 IRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 ++P A PPAP P A +A AAA P +P P + PA PR A A Sbjct: 99 VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP----VAAAAPARAPRAAAA 154 Query: 108 VPAAPSPGPLPARP----------SSPPPRPSL------PSGPHRPVLPPSALAAPRPPL 151 AP P P PA+P ++PPP P+ P+GP R PP A+AA PPL Sbjct: 155 AATAP-PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRR--APPPAVAAREPPL 211 Query: 152 ARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHAG 187 P PQ A Q+Q+P + PE G V AG Sbjct: 212 PPP-PQ--PPAPPQQQQPPPPQPQPPPEG-GAVRAG 243 Score = 64.3 bits (155), Expect = 6e-11 Identities = 53/157 (33%), Positives = 61/157 (38%), Gaps = 14/157 (8%) Query: 24 RVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP------RERPAAARLSALAAAQP 77 R G P P A A P PA PPAP P AA +A A P Sbjct: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162 Query: 78 RRRSPGPQGGGGGDIASPLP-PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHR 136 PGP+ +A+P P PA P AP PA P P PA + PP P P + Sbjct: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAP--PAGPRRAPPPAVAAREPPLPP----PPQ 216 Query: 137 PVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRR 173 P PP P PP +P P+G RP S R Sbjct: 217 PPAPPQQ-QQPPPPQPQPPPEGGAVRAGGAARPVSLR 252 Score = 38.9 bits (89), Expect = 0.003 Identities = 48/182 (26%), Positives = 63/182 (34%), Gaps = 40/182 (21%) Query: 35 LPGPALVVAGLDGIRPAPAAAHP----------PAPRERPAAARLSALAAAQPRRRSPGP 84 LP P A + +AA P + R R A L + RR P P Sbjct: 7 LPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEP 66 Query: 85 QGGGG-----------------GDIASPLPPALQP--RGA--PAVPAAPSPGPLPARPSS 123 + G I+ +QP RGA PA P AP P A ++ Sbjct: 67 ERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAA 126 Query: 124 PPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQ--EQRPRSRRRAGAPEAL 181 PPP P+ P PP+ +AA P A + TA +P R + AP A Sbjct: 127 PPPTPAPPP-------PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAA 179 Query: 182 GP 183 P Sbjct: 180 PP 181 Score = 30.4 bits (67), Expect = 1.00 Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 21/115 (18%) Query: 49 RPAPAAAH-------PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQ 101 RPA A H P + +ER Q R P P G G + S A+ Sbjct: 355 RPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAP-GSGTRQVFSMA--AMN 411 Query: 102 PRGAPAV----PAAPSPGPLPARPSSPPPRPSLPSGPHRPV-LPPSALAAPRPPL 151 G A P +PSP PL PP +P+LP P PP P P+ Sbjct: 412 KEGGTASVATGPDSPSPVPL------PPGKPALPGADGTPFGCPPGRKEKPSDPV 460 Score = 28.1 bits (61), Expect = 4.9 Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 21/99 (21%) Query: 50 PAPAAAH---PPAPRERPAAARLSALAAAQPRR-----RSPGPQGGGGGDIASPLPPALQ 101 PAP PP P+ P + A AA+P R G GG GG + L Sbjct: 218 PAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLL 277 Query: 102 PR-------------GAPAVPAAPSPGPLPARPSSPPPR 127 GA A+P PG P S+ P R Sbjct: 278 EEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSR 316 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 65.9 bits (159), Expect = 2e-11 Identities = 46/126 (36%), Positives = 57/126 (45%), Gaps = 14/126 (11%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P P A PP+P+ PAA A+ P P P+ G A+PL P+GAP P Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK---GSPAATPL-----PKGAPTTP 1060 Query: 110 AA--PSPGPLPARPS---SPPPRPSLPSGPHRPVLPPSALAAPRPPLAR-PLPQGSVTAR 163 AA PSP PA PS +P P + P P PS AP PP A P P+G + Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120 Query: 164 EQEQRP 169 + P Sbjct: 1121 PHKGAP 1126 Score = 61.6 bits (148), Expect = 4e-10 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 13/123 (10%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI--ASPLPPALQPRGAPAVP 109 P AA PP+P+ PAA L A P P P+GG +P PPA P P Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094 Query: 110 AAPSPGPLPARPSSPPPRPS--LPSGPHRPVLPPSALAAPRPPLARP-LPQGSVTAREQE 166 A PSP P P++ PP P L + PH+ AP P A P P+G + + Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHK--------GAPTTPAATPPSPKGGLATPPPK 1146 Query: 167 QRP 169 P Sbjct: 1147 GAP 1149 Score = 58.9 bits (141), Expect = 3e-09 Identities = 41/116 (35%), Positives = 47/116 (40%), Gaps = 9/116 (7%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG--GDIASPLPPALQPRGAPA 107 P P AA PP+P+ PA A P P P+GG +P PPA P Sbjct: 940 PTPPAATPPSPKGGPATPS-PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998 Query: 108 VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR-PLPQGSVTA 162 PA PSP P P+ PP P P P A PP A P P+GS A Sbjct: 999 GPATPSPKGAPTPPAVTPPSPK-----GSPAATPFPKGASTPPAATPPSPKGSPAA 1049 Score = 57.4 bits (137), Expect = 8e-09 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 14/141 (9%) Query: 30 PGGFCLPG---PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQG 86 P G LP P V L + PA PAP++ PA + S+ + + R +P P+G Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPAT---PAPKQAPALSMTSS--SPKKARATPAPKG 929 Query: 87 --GGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPR----PSLPSGPHRPVLP 140 +P PPA P PA PSP P P++ PP P+ PS P P Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989 Query: 141 PSALAAPRPPLARPLPQGSVT 161 + +P+ A P P+G+ T Sbjct: 990 AATPPSPKGGPATPSPKGAPT 1010 Score = 55.1 bits (131), Expect = 4e-08 Identities = 43/141 (30%), Positives = 58/141 (41%), Gaps = 30/141 (21%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-------GGGDIASPLPPALQ- 101 P P AA PP+P+ A A P P P+GG G + PP+ + Sbjct: 1103 PMPPAATPPSPKGGLATPPHKG-APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161 Query: 102 ------PRGAPAVPAA-----------PSPGPLPARPSSPPPRP----SLPSGPHRPVLP 140 P+GAP PAA PSP P P++ PP P + PS P P Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221 Query: 141 PSALAAPRPPLARPLPQGSVT 161 + +P+ LA P P+G+ T Sbjct: 1222 AATPPSPKGGLATPSPKGAPT 1242 Score = 54.7 bits (130), Expect = 5e-08 Identities = 45/134 (33%), Positives = 55/134 (41%), Gaps = 15/134 (11%) Query: 58 PAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIA--SPLPPALQPRGAPAVPAAPSPG 115 PAP+ PA+ A P P P+GG +P PPA P PA PSP Sbjct: 925 PAPKGIPASPSPKG-APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983 Query: 116 PLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPP-LARPLPQGSVTAREQEQRPRSRRR 174 P P++ PP P GP PS AP PP + P P+GS A P + Sbjct: 984 GAPTPPAATPPSPK--GGP----ATPSPKGAPTPPAVTPPSPKGSPAA-----TPFPKGA 1032 Query: 175 AGAPEALGPVHAGS 188 + P A P GS Sbjct: 1033 STPPAATPPSPKGS 1046 Score = 54.3 bits (129), Expect = 6e-08 Identities = 38/109 (34%), Positives = 46/109 (42%), Gaps = 15/109 (13%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P PA PP+P+ PA + A P P P+G G PP P+GAP P Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPG------TPP---PKGAPTPP 1336 Query: 110 AAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQG 158 A P P P+ P PS GP PS+ P PP A P +G Sbjct: 1337 AVTPPSP-KGTPTLPATTPSSKGGP----TTPSSKEGPTPPAATPSHKG 1380 Score = 53.9 bits (128), Expect = 8e-08 Identities = 41/117 (35%), Positives = 49/117 (41%), Gaps = 18/117 (15%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P P AA PP+P+ PA A P P P+GG P P+GAP P Sbjct: 963 PTPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGG---------PATPSPKGAPTPP 1012 Query: 110 AA--PSPGPLPA-----RPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR-PLPQG 158 A PSP PA + +S PP + PS P P AP P A P P+G Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069 Score = 51.2 bits (121), Expect = 5e-07 Identities = 41/116 (35%), Positives = 49/116 (42%), Gaps = 27/116 (23%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P AA PP+P+ A A P P P+GG +A+P P+GAP P Sbjct: 1172 PTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGG----LATP-----SPKGAPTTP 1221 Query: 110 AA-----------PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARP 154 AA PSP P P++ PP P GP P PP AP PP A P Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPK--GGPATP--PPK--GAPTPPAATP 1271 Score = 50.4 bits (119), Expect = 9e-07 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 15/136 (11%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P A PP+P+E PA +++ ++ + +P P G +P PA+ P VP Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG-------APTLPAVIPSSPKEVP 1517 Query: 110 AAPSPGPLPARPSSPPPRPSLPS--GPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQ 167 A PS P P++ P+ P ++PP A+ P P +P T +E Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP-AMTVPSPKKTPAIP----TPKEAPA 1572 Query: 168 RPRSRRRAGAPEALGP 183 P S + A +P A+ P Sbjct: 1573 TP-SSKEASSPPAVTP 1587 Score = 48.5 bits (114), Expect = 4e-06 Identities = 46/165 (27%), Positives = 59/165 (35%), Gaps = 22/165 (13%) Query: 31 GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90 GG P P P AA PP+P+ PA A P P +GG Sbjct: 1230 GGLATPSPKGA--------PTTPAATPPSPKGGPATPPPKG-APTPPAATPPSLKGG--- 1277 Query: 91 DIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSL--PSGPHRPVLPPSALAAPR 148 +A+P P P A P +P GP + P P P+ PS P PP A Sbjct: 1278 -LATP-PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335 Query: 149 PPLARPLPQGSVTAREQEQRPR------SRRRAGAPEALGPVHAG 187 P + P P+G+ T + S + P A P H G Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380 Score = 42.7 bits (99), Expect = 2e-04 Identities = 42/144 (29%), Positives = 52/144 (36%), Gaps = 20/144 (13%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL---------PPALQP 102 PA P PA LS A G GD+ P P P Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452 Query: 103 RGAPAVPAAPSPGPLPA-RPSSP--PPRP---SLPSGPHRPVLPPSALAAPRPPLARPLP 156 +G PA P++ LPA P SP PP P + S P + P+ + AP P P Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP-- 1510 Query: 157 QGSVTAREQEQRPRSRRRAGAPEA 180 + +E P SRR AP A Sbjct: 1511 ---SSPKEVPATPSSRRDPIAPTA 1531 Score = 41.2 bits (95), Expect = 6e-04 Identities = 42/159 (26%), Positives = 56/159 (35%), Gaps = 9/159 (5%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 P +P P A + + APA PA + A P+ P Sbjct: 1550 PPAMTVPSPKKTPA-IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP-SLPSGPHRPVLPPSALAAPR 148 +P PPA+ P PA P+P P+SPP P SL P P + A Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAP---KGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665 Query: 149 PPLARPLP--QGSVTARE--QEQRPRSRRRAGAPEALGP 183 P ++ LP +G +E P S AP GP Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704 Score = 40.4 bits (93), Expect = 0.001 Identities = 44/154 (28%), Positives = 55/154 (35%), Gaps = 32/154 (20%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-----------GGGDIAS---- 94 P P AA PP+P+ P A P P P+G GG S Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKG-APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368 Query: 95 PLPPALQP--RGAPAV--------PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSAL 144 P PPA P +G PA+ PA PSP P P+ P P P PV A Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK--KAPATPVTREGAA 1426 Query: 145 AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178 + L P +VT ++ P + G P Sbjct: 1427 TPSKGDLTPP----AVTPVSLKKAPATSAPKGGP 1456 Score = 35.8 bits (81), Expect = 0.024 Identities = 38/132 (28%), Positives = 52/132 (39%), Gaps = 20/132 (15%) Query: 53 AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 A+ P P P + + L AA + P P+ A+P PP ++P AP Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS--AAPSPPV-------SLPLAP 1804 Query: 113 SPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRP-----PLARPLP-QGSVTAREQE 166 SP P + PP + LPS P + PS AP PL P P G V + Sbjct: 1805 SPVP-----TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859 Query: 167 QRPRSRRRAGAP 178 + + AG P Sbjct: 1860 VNMPTPKSAGIP 1871 Score = 35.0 bits (79), Expect = 0.040 Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 15/159 (9%) Query: 30 PGGFCLPGPALVVAG-LDGIRPAPA---AAHPPAPRERPAAARLSALA-AAQPRRRSPGP 84 P C P LV+A + P+P+ A PP ++ + SALA A + P Sbjct: 714 PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773 Query: 85 QGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSAL 144 G +S A SP PL S RP G P P L Sbjct: 774 DSGASATASSK---------GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNL 824 Query: 145 AAPRPPL-ARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182 ++P P+ A LP+ S++ + + P + P G Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863 Score = 34.7 bits (78), Expect = 0.053 Identities = 44/197 (22%), Positives = 71/197 (36%), Gaps = 50/197 (25%) Query: 35 LPGPALVVAG-------LDGIRP----APAAAHPP-APRERPAAARLSA----------- 71 +P P+L AG +DGI AP A+ P P E A+ ++ Sbjct: 734 VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793 Query: 72 -----LAAAQPRRRSPGPQGGGG-----GDIASPLPP---------ALQPRGAPAVPAAP 112 ++ + +R P +G G G+++SP+ P +L +G+ PA Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853 Query: 113 SPGPLPARPSSPPPRPSLPSGPHRPVLPPSA--------LAAPRPPLARPLPQGSVTARE 164 P+ +P P P P LPP L P+ A P P+ + Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913 Query: 165 QEQRPRSRRRAGAPEAL 181 P+ R AP+ + Sbjct: 914 TSSSPKKARATPAPKGI 930 Score = 32.0 bits (71), Expect = 0.34 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 5/89 (5%) Query: 94 SPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR 153 SP PP+ P+GAP P+A +P P + PP PS + P P A P P A Sbjct: 855 SPTPPS--PKGAPT-PSAVTPLS-PKGVTLPPKETPTPSVVNLP-FPKEGPATPAPKQAP 909 Query: 154 PLPQGSVTAREQEQRPRSRRRAGAPEALG 182 L S + ++ P + +P G Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKG 938 Score = 27.7 bits (60), Expect = 6.5 Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 4/52 (7%) Query: 110 AAPSPGPLPARPSSPPPR--PSLPSGPHRPVLPPSALAAPRPPLARPLPQGS 159 A PGP P SP P+ P + P PS +A+ PL P PQ S Sbjct: 37 ALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAS--TPLEVPFPQSS 86 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 61.6 bits (148), Expect = 4e-10 Identities = 41/107 (38%), Positives = 45/107 (42%), Gaps = 5/107 (4%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAA 111 P PPAP RP + L P P + G + PLP L P P P Sbjct: 411 PPLGPPPAPPLRPPGPP-TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469 Query: 112 PSPGPLPARPSSPPPR---PSLPSGPHRPVLPPSALAAPRPPLARPL 155 P PGP P P PPPR P LP P P +PP RPPL PL Sbjct: 470 PPPGPPPGLPPGPPPRGPPPRLPP-PAPPGIPPPRPGMMRPPLVPPL 515 Score = 47.8 bits (112), Expect = 6e-06 Identities = 50/170 (29%), Positives = 61/170 (35%), Gaps = 34/170 (20%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG-GDIAS 94 PGP G+ P P PP R + L PR PGP G G Sbjct: 424 PGPPT------GLPPGPPPGAPPFLRP----PGMPGLRGPLPRLLPPGPPPGRPPGPPPG 473 Query: 95 P---LPPALQPRGAP------AVPAAPSPGPLPARPSSPPPRPSLPSG--PHRPVLPPSA 143 P LPP PRG P A P P P P RP PP P G P P+ P Sbjct: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGV 533 Query: 144 LAAPRPPLARPLPQ------------GSVTAREQEQRPRSRRRAGAPEAL 181 L+AP + RP +++A+ Q P++ P AL Sbjct: 534 LSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTAL 583 Score = 43.9 bits (102), Expect = 9e-05 Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 14/129 (10%) Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSP 114 A + ++ + + A ++++P PQ I +P P P G P P P Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424 Query: 115 GPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRR 174 GP P PPP P L P + R PL R LP G R P Sbjct: 425 GPPTGLPPGPPPGAP-------PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP----- 472 Query: 175 AGAPEALGP 183 G P L P Sbjct: 473 -GPPPGLPP 480 Score = 28.1 bits (61), Expect = 4.9 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 11/70 (15%) Query: 119 ARPSSPPPR----PSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRR 174 A P S PP P +P P P+ PP P PPL P P + P R Sbjct: 392 APPQSVPPSQIQAPPMPGPP--PLGPP-----PAPPLRPPGPPTGLPPGPPPGAPPFLRP 444 Query: 175 AGAPEALGPV 184 G P GP+ Sbjct: 445 PGMPGLRGPL 454 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 60.5 bits (145), Expect = 9e-10 Identities = 58/166 (34%), Positives = 61/166 (36%), Gaps = 17/166 (10%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPA-------LVVAGLDGIRPAPAA 54 PGG A F RG G R PGG PGPA AG RP Sbjct: 189 PGGSSRAAFPQGGRGRG-----RFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP 243 Query: 55 AHPPAPRERPAAAR-LSALAAAQPRR--RSPGPQGGGGGDIASPLPPALQPRGAPAVPA- 110 PP P P + L A P R R P P G P L P P VP Sbjct: 244 PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGY 303 Query: 111 APSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLP 156 P PGP P + PPP P P P+ PP LA P P L P P Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP-PHLPGPPP 348 Score = 41.2 bits (95), Expect = 6e-04 Identities = 32/84 (38%), Positives = 34/84 (40%), Gaps = 9/84 (10%) Query: 80 RSPGPQGGGGGDIASPL--PPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRP 137 R PGP G GG P P P G P P PGP P PPP P+ RP Sbjct: 216 RFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPPLAGPPNRGDRP 273 Query: 138 VLPPSALAAPRP---PLARPLPQG 158 PP L +P P PLP G Sbjct: 274 --PPPVLFPGQPFGQPPLGPLPPG 295 Score = 39.7 bits (91), Expect = 0.002 Identities = 30/79 (37%), Positives = 33/79 (41%), Gaps = 2/79 (2%) Query: 80 RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVL 139 R+ PQGG G P PA P P P P PA + P P P P GP P Sbjct: 194 RAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPP-PFPAGQTPPRP-PLGPPGPPGPPG 251 Query: 140 PPSALAAPRPPLARPLPQG 158 PP PPLA P +G Sbjct: 252 PPPPGQVLPPPLAGPPNRG 270 Score = 32.0 bits (71), Expect = 0.34 Identities = 36/129 (27%), Positives = 40/129 (31%), Gaps = 12/129 (9%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAH-----PPAPRERPAAARLSALAAAQPRRRSPGP 84 P G PGP V G G P P PP P L P PGP Sbjct: 288 PLGPLPPGPPPPVPGY-GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP 346 Query: 85 QGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARP-SSPPPRPSLPSGPHRPVLPPSA 143 G P P +P + S GP P P PPP GP P Sbjct: 347 PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP-----PGRE 401 Query: 144 LAAPRPPLA 152 + R PL+ Sbjct: 402 MDTARTPLS 410 >gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] Length = 651 Score = 57.8 bits (138), Expect = 6e-09 Identities = 58/159 (36%), Positives = 63/159 (39%), Gaps = 32/159 (20%) Query: 16 GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-----LS 70 GGG G GVG G PGPA G PAP PP P + AA R LS Sbjct: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRP--PPEPDDAAAALRLALDQLS 67 Query: 71 AL-----------AAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA-APSPGPLP 118 AL AA + G G GG P+PP GAP A A +PG LP Sbjct: 68 ALGLGGAGDTDEEGAAGDGAAAAG--GADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLP 125 Query: 119 ------ARPSSPPPRPSLPS-----GPHRPVLPPSALAA 146 + P PPPRPS P PH L P L A Sbjct: 126 LLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLA 164 Score = 30.0 bits (66), Expect = 1.3 Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 32/137 (23%) Query: 35 LPGPALVVAGLDGIRPAPAAAH------PPAPRERPAAARLSALAAAQPRRRSPGPQGGG 88 +P A + A + P PA + P P PAA + A PR P+ GG Sbjct: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGP---PAAGARRSSGAGTPRHSPTLPEPGG 522 Query: 89 GGDIASPLPPALQPRGAP----AVPAAPSPGP--------------LPARPSSPPPRPSL 130 + LP L RGAP A+ P GP LP+ P++ P Sbjct: 523 ---LRLELP--LSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLD 577 Query: 131 PSGPHRPVLPPSALAAP 147 PPSA +AP Sbjct: 578 SGASENSRKPPSASSAP 594 Score = 29.3 bits (64), Expect = 2.2 Identities = 26/78 (33%), Positives = 29/78 (37%), Gaps = 2/78 (2%) Query: 7 AARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPA--PAAAHPPAPRERP 64 AA GAA GG G V G P L A G P P A+ PP P RP Sbjct: 82 AAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRP 141 Query: 65 AAARLSALAAAQPRRRSP 82 + + A A P P Sbjct: 142 SPPDVFAGFAPHPAALGP 159 Score = 27.3 bits (59), Expect = 8.4 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 5/83 (6%) Query: 65 AAARLSALAAAQPRRRSPGPQGGGGGDIA--SPLPPALQPRGAPAVPAAPSPGPLPARPS 122 AAA L A Q RR P G GD A +P P G+ P+ P PGP A P Sbjct: 368 AAASLWAKTPNQGRR-PPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGP--ASPY 424 Query: 123 SPPPRPSLPSGPHRPVLPPSALA 145 S G P P A Sbjct: 425 SGSGNGGFAFGAEGPGAPVGTAA 447 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 57.4 bits (137), Expect = 8e-09 Identities = 44/118 (37%), Positives = 50/118 (42%), Gaps = 19/118 (16%) Query: 31 GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90 GG LP P +V G G R P PP P +A P R P P G GG Sbjct: 322 GGNQLPRPP-IVGGNKG-RSGPL---PPVPL---------GIAPPPPTPRGPPPPGRGG- 366 Query: 91 DIASPLPPALQPRGAPAVPAAPSPG--PLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146 P PP R P P P G P+P P PPP PS +GP P LPP+ + A Sbjct: 367 --PPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPA 422 Score = 41.6 bits (96), Expect = 4e-04 Identities = 43/132 (32%), Positives = 49/132 (37%), Gaps = 21/132 (15%) Query: 44 GLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIAS-PL---PPA 99 GL+ +R P P P+ PR G G G + PL PP Sbjct: 299 GLEAVRQEMRRQEPLPPPPPPSRG-----GNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP 353 Query: 100 LQPRGAPAV-PAAPSPGPLPAR----PSSPPP----RPSLPSGPHRPVLPPSALAAPRPP 150 PRG P P P P PA P PPP P +P P P PPS+ P PP Sbjct: 354 PTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPP 413 Query: 151 LARPLPQGSVTA 162 PLP V A Sbjct: 414 ---PLPPALVPA 422 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 57.0 bits (136), Expect = 1e-08 Identities = 47/147 (31%), Positives = 52/147 (35%), Gaps = 22/147 (14%) Query: 30 PGGFCLPGPALVVAGLDGIRPAP----AAAHPPAPRER----PAAARLSALAAAQPRRRS 81 PGG C+ P + G P P A PP P P+ + L A P Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 672 Query: 82 PG--------PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG 133 PG P G I P PP G P P P PLP P PPP P P G Sbjct: 673 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP-----PPPPPLPGGPGIPPP-PPFPGG 726 Query: 134 PHRPVLPPSALAAPRPPLARPLPQGSV 160 P P PP P PP +P V Sbjct: 727 PGIPPPPPGMGMPPPPPFGFGVPAAPV 753 Score = 45.4 bits (106), Expect = 3e-05 Identities = 44/139 (31%), Positives = 49/139 (35%), Gaps = 26/139 (18%) Query: 26 GVGEPGGFCLPGPALVVAGLDGIRPAPAAAH-PPAPRERPAAARLSALAAAQPRRRSPGP 84 GVG P LPG + P P +A PP P P +A + P P Sbjct: 651 GVGIPSPSSLPGGTAIPPP----PPLPGSARIPPPPPPLPGSAGI------------PPP 694 Query: 85 QGGGGGDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPRPSLPSGPHRPVL 139 G+ P PP P G P P PG P P PPP P P PVL Sbjct: 695 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVL 754 Query: 140 P----PSALAAPRPPLARP 154 P P L P L RP Sbjct: 755 PFGLTPKKLYKPEVQLRRP 773 Score = 38.9 bits (89), Expect = 0.003 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 16/81 (19%) Query: 94 SPLPPA--LQPRGAPAVPAAPSPG------PLPARPSSPPPRPSLPSGPHRPVLPPSALA 145 +P+PPA L +P P+PG P P P PPP P P LP Sbjct: 571 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI 630 Query: 146 APRPPLA--------RPLPQG 158 +P PPL+ PLP+G Sbjct: 631 SPPPPLSGDATIPPPPPLPEG 651 Score = 33.5 bits (75), Expect = 0.12 Identities = 31/96 (32%), Positives = 34/96 (35%), Gaps = 32/96 (33%) Query: 90 GDIASPLPPALQPRGAPAVPAA---PSPGPLPARPSSPPPRP------------------ 128 GD +P PP P P +P SP LP + PP P Sbjct: 594 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 653 Query: 129 -----SLPSG---PHRPVLPPSALAAPRPPLARPLP 156 SLP G P P LP SA P PP PLP Sbjct: 654 IPSPSSLPGGTAIPPPPPLPGSARIPPPPP---PLP 686 Score = 31.6 bits (70), Expect = 0.45 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 93 ASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA 152 A +PP++ P AP PA PLP + P P P P PP P PP Sbjct: 560 AITVPPSV-PSRAPVPPA----PPLPGDSGTIIPPPPAPGDSTTPPPPP-----PPPPPP 609 Query: 153 RPLPQG 158 PLP G Sbjct: 610 PPLPGG 615 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 57.0 bits (136), Expect = 1e-08 Identities = 47/147 (31%), Positives = 52/147 (35%), Gaps = 22/147 (14%) Query: 30 PGGFCLPGPALVVAGLDGIRPAP----AAAHPPAPRER----PAAARLSALAAAQPRRRS 81 PGG C+ P + G P P A PP P P+ + L A P Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681 Query: 82 PG--------PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG 133 PG P G I P PP G P P P PLP P PPP P P G Sbjct: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP-----PPPPPLPGGPGIPPP-PPFPGG 735 Query: 134 PHRPVLPPSALAAPRPPLARPLPQGSV 160 P P PP P PP +P V Sbjct: 736 PGIPPPPPGMGMPPPPPFGFGVPAAPV 762 Score = 45.4 bits (106), Expect = 3e-05 Identities = 44/139 (31%), Positives = 49/139 (35%), Gaps = 26/139 (18%) Query: 26 GVGEPGGFCLPGPALVVAGLDGIRPAPAAAH-PPAPRERPAAARLSALAAAQPRRRSPGP 84 GVG P LPG + P P +A PP P P +A + P P Sbjct: 660 GVGIPSPSSLPGGTAIPPP----PPLPGSARIPPPPPPLPGSAGI------------PPP 703 Query: 85 QGGGGGDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPRPSLPSGPHRPVL 139 G+ P PP P G P P PG P P PPP P P PVL Sbjct: 704 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVL 763 Query: 140 P----PSALAAPRPPLARP 154 P P L P L RP Sbjct: 764 PFGLTPKKLYKPEVQLRRP 782 Score = 38.9 bits (89), Expect = 0.003 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 16/81 (19%) Query: 94 SPLPPA--LQPRGAPAVPAAPSPG------PLPARPSSPPPRPSLPSGPHRPVLPPSALA 145 +P+PPA L +P P+PG P P P PPP P P LP Sbjct: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI 639 Query: 146 APRPPLA--------RPLPQG 158 +P PPL+ PLP+G Sbjct: 640 SPPPPLSGDATIPPPPPLPEG 660 Score = 33.5 bits (75), Expect = 0.12 Identities = 31/96 (32%), Positives = 34/96 (35%), Gaps = 32/96 (33%) Query: 90 GDIASPLPPALQPRGAPAVPAA---PSPGPLPARPSSPPPRP------------------ 128 GD +P PP P P +P SP LP + PP P Sbjct: 603 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 662 Query: 129 -----SLPSG---PHRPVLPPSALAAPRPPLARPLP 156 SLP G P P LP SA P PP PLP Sbjct: 663 IPSPSSLPGGTAIPPPPPLPGSARIPPPPP---PLP 695 Score = 31.6 bits (70), Expect = 0.45 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 93 ASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA 152 A +PP++ P AP PA PLP + P P P P PP P PP Sbjct: 569 AITVPPSV-PSRAPVPPA----PPLPGDSGTIIPPPPAPGDSTTPPPPP-----PPPPPP 618 Query: 153 RPLPQG 158 PLP G Sbjct: 619 PPLPGG 624 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 57.0 bits (136), Expect = 1e-08 Identities = 53/163 (32%), Positives = 59/163 (36%), Gaps = 29/163 (17%) Query: 49 RPAPAAAHPPAPRERPAAARLSALAAAQPRR----RSPG--------------PQGGG-- 88 RP PPA RP+A L + R PG P GG Sbjct: 458 RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAP 517 Query: 89 --GGDIASPLP---PALQPR-GAPAVPAAPSPG---PLPARPSSPPPRPSLPSGPHRPVL 139 G SP P PA +P GA P P PG P A PS+PP P LP P P Sbjct: 518 TPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPA 577 Query: 140 PPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182 PP P PP P P G+ P G P+ALG Sbjct: 578 PPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620 Score = 47.8 bits (112), Expect = 6e-06 Identities = 40/120 (33%), Positives = 45/120 (37%), Gaps = 23/120 (19%) Query: 25 VGVGEPGGFCLPGPALVVAG-----LDGIRPAPAAAHPP--------APRERPAAARLSA 71 V V P G P P + PAP AA PP +P+E P SA Sbjct: 506 VAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPP----SA 561 Query: 72 LAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLP 131 A P SP P A PLP L P P P + GP+P P PPP P P Sbjct: 562 PPQAPPLPGSPEPPP------APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGP 615 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 56.6 bits (135), Expect = 1e-08 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 17/129 (13%) Query: 53 AAAHPPAPRERP-------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--- 102 ++A PA E P ++A L AA +P QG G +A P PP L P Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPA 324 Query: 103 RGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS--V 160 + + A+P P P P P PS+ PP P P P LP P PP A PLP + Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPP-----PPPPPLPNQVPPPPPPPPAPPLPASGFFL 379 Query: 161 TAREQEQRP 169 + ++ RP Sbjct: 380 ASMSEDNRP 388 Score = 42.4 bits (98), Expect = 3e-04 Identities = 28/85 (32%), Positives = 30/85 (35%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P AA PA L LA P PGP P PP P + P Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348 Query: 110 AAPSPGPLPARPSSPPPRPSLPSGP 134 P P PLP + PPP P P P Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLP 373 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 56.6 bits (135), Expect = 1e-08 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 17/129 (13%) Query: 53 AAAHPPAPRERP-------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--- 102 ++A PA E P ++A L AA +P QG G +A P PP L P Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPA 324 Query: 103 RGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS--V 160 + + A+P P P P P PS+ PP P P P LP P PP A PLP + Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPP-----PPPPPLPNQVPPPPPPPPAPPLPASGFFL 379 Query: 161 TAREQEQRP 169 + ++ RP Sbjct: 380 ASMSEDNRP 388 Score = 42.4 bits (98), Expect = 3e-04 Identities = 28/85 (32%), Positives = 30/85 (35%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P AA PA L LA P PGP P PP P + P Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348 Query: 110 AAPSPGPLPARPSSPPPRPSLPSGP 134 P P PLP + PPP P P P Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLP 373 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 56.6 bits (135), Expect = 1e-08 Identities = 63/199 (31%), Positives = 76/199 (38%), Gaps = 28/199 (14%) Query: 6 QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAA-AHPPAPRERP 64 Q R G + G G + VG P G +PG + GL G + AP H AP P Sbjct: 618 QQGRPGPSGVAGPQGEKGDVGPAGPPG--VPGSVVQQEGLKGEQGAPGPRGHQGAPG--P 673 Query: 65 AAARLSALAAAQPRRRSPGPQG--GGGGDIASPLPPALQ----PRGAPAVPAAPSPGPLP 118 AR + R PG QG G GD+ P P L P G P VP P PG P Sbjct: 674 PGAR--GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731 Query: 119 ARPSS-------PPPRPSLP---SGPHRPVLPPSALAAPRPPLARPLP-----QGSVTAR 163 P PP P+ P GP+ P PP P LP +G + + Sbjct: 732 GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791 Query: 164 EQEQRPRSRRRAGAPEALG 182 RP + AG P A G Sbjct: 792 GLAGRPGEKGEAGLPGAPG 810 Score = 45.8 bits (107), Expect = 2e-05 Identities = 58/204 (28%), Positives = 73/204 (35%), Gaps = 27/204 (13%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGV----GEPGGFCLPGPALVV--AGLDGIRPAPAAA 55 P G Q R GA G G + GV G PG PG + AG GI+ +P Sbjct: 1166 PQGSQGER-GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224 Query: 56 HPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA----A 111 PP P+ + + R PGP G G LP RG P + Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284 Query: 112 PSPGP--------LPARPSSP----PPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS 159 +PGP LP + P P+ P GP P PP +P P P P G+ Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP-GEPGPSGT 1343 Query: 160 VTAREQEQRPRSRRRAGAPEALGP 183 + + S G P LGP Sbjct: 1344 PGQKGSKGENGS---PGLPGFLGP 1364 Score = 41.2 bits (95), Expect = 6e-04 Identities = 55/179 (30%), Positives = 62/179 (34%), Gaps = 27/179 (15%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 GE G LPG L G R A P P P L P R PG QG Sbjct: 822 GEKGELGLPG-------LKGDRGEKGEAGPAGPPGLPGTTSLFT-----PHPRMPGEQGP 869 Query: 88 GG--GDIASPLPPALQPRGAPAVPAAPS--PGPLPARPSSPPP----RPSLPS--GPHRP 137 G GD P P LQ R P P+ PG + P P P G P Sbjct: 870 KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP 929 Query: 138 VLPPSALAAP--RPPLARPLPQGSVTAREQEQRP---RSRRRAGAPEALGPVHAGSDLE 191 PP ++ AP R + +G A +E P R GAP GP G D E Sbjct: 930 SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE 988 Score = 40.8 bits (94), Expect = 7e-04 Identities = 52/198 (26%), Positives = 66/198 (33%), Gaps = 37/198 (18%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 GE G LPG + G DG P PR P +PG +G Sbjct: 1291 GESGAMGLPGQE-GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349 Query: 88 GGGDIASPLPPALQPRGAPAVP---AAPSPGPLPARPSSP----------------PP-- 126 G + + LP L PRG P P P +P +P P PP Sbjct: 1350 KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 1409 Query: 127 --RPSLPSGP----HRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180 +P P P H ++ P L P+ P P G Q P R + + E Sbjct: 1410 KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG------QPGFPGLRGESPSMET 1463 Query: 181 LGPV---HAGSDLELRLA 195 L + G LE RLA Sbjct: 1464 LRRLIQEELGKQLETRLA 1481 Score = 39.3 bits (90), Expect = 0.002 Identities = 42/147 (28%), Positives = 53/147 (36%), Gaps = 31/147 (21%) Query: 1 MPGGVQAARFGAAVRGGG----AGRRVRVGVGEPGGFCLPG----PALVVAGLDGIRPAP 52 +PG + VRG G+ V+ G PG PG P + VAG P Sbjct: 997 LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAG------PP 1050 Query: 53 AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 + PP + P + L PGPQG G D A P P G P + + Sbjct: 1051 GPSGPPGDKGSPGSRGLPGF---------PGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101 Query: 113 SPGPLPAR--------PSSPPPRPSLP 131 SPG + P PP P LP Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLP 1128 Score = 38.9 bits (89), Expect = 0.003 Identities = 51/183 (27%), Positives = 59/183 (32%), Gaps = 33/183 (18%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQG- 86 G PG PG V G G P + P R P A SPGP G Sbjct: 910 GAPGAAGNPGAPGHV-GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP 968 Query: 87 -GGGGDIASPLPPALQPRGAPAVPAAPS-PGPLPARPSSPPPR----------------- 127 G G P PP G P + +P PGPL + + R Sbjct: 969 RGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028 Query: 128 -PSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHA 186 P +P P P +A P P P +GS P SR G P GP A Sbjct: 1029 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS---------PGSRGLPGFPGPQGP--A 1077 Query: 187 GSD 189 G D Sbjct: 1078 GRD 1080 Score = 32.7 bits (73), Expect = 0.20 Identities = 54/194 (27%), Positives = 62/194 (31%), Gaps = 33/194 (17%) Query: 6 QAARFGAAVRGGGAGRRVRVGV----GEPGGFCLPGPALVVAGLDGIRPAPAAAH----- 56 Q GA G G VG G PG PG G DG R AA Sbjct: 905 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG-LRGTPGKDGERGEKGAAGEEGSP 963 Query: 57 -PPAPRERPAAARLSALAA----AQPRRRS----PGPQGG--------GGGDIASPLPPA 99 P PR P A L +P R PGP G G + A Sbjct: 964 GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV 1023 Query: 100 LQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG----PHRPVLPPSALAAPRPPLARPL 155 RGAP +P +P P + PP PS P G P LP P+ P R Sbjct: 1024 KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP--GFPGPQGPAGRDG 1081 Query: 156 PQGSVTAREQEQRP 169 G+ R +P Sbjct: 1082 APGNPGERGPPGKP 1095 Score = 32.7 bits (73), Expect = 0.20 Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 25/130 (19%) Query: 28 GEPGGFCLPGP-ALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAA-----------A 75 G+PG LPGP G G+R +P P + R S A A Sbjct: 970 GDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029 Query: 76 QPRRRSPGPQGGGGGDIASPLPPALQP--------RGAPAVPAAPSPGPLPARPSSP--- 124 SPG +G G +A P P+ P RG P P P P +P Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089 Query: 125 --PPRPSLPS 132 P +P L S Sbjct: 1090 GPPGKPGLSS 1099 Score = 32.0 bits (71), Expect = 0.34 Identities = 54/215 (25%), Positives = 72/215 (33%), Gaps = 63/215 (29%) Query: 19 AGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPR 78 AG + +GV P G LPGP + I P A P P+ + + Sbjct: 480 AGEKGEMGVAGPMG--LPGPK---GDIGAIGPVGA----PGPKGEKGDVGIGPFGQGEKG 530 Query: 79 RRS----PGPQGGGG--------GDIASP-LPPALQPRGAPAVPAAPSPGPLPARPSSP- 124 + PGP G G G++ P LP + RG P P P P R +P Sbjct: 531 EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGP---PGRVGAPG 587 Query: 125 ----------------------PPRPSLPSGPHRPVLPPSALAAPR------PPLARPLP 156 P +P RP PS +A P+ P P Sbjct: 588 LQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRP--GPSGVAGPQGEKGDVGPAGPPGV 645 Query: 157 QGSVTARE----QEQRPRSRRRAGA---PEALGPV 184 GSV +E ++ P R GA P A GP+ Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI 680 Score = 29.3 bits (64), Expect = 2.2 Identities = 44/171 (25%), Positives = 51/171 (29%), Gaps = 33/171 (19%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G PG L P + G G P P P E R L P GP G Sbjct: 849 GLPGTTSLFTPHPRMPGEQG--PKGEKGDPGLPGEPGLQGRPGELGPQGPT----GPPGA 902 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSL----------------P 131 G + A P A GAP AP P P +P R + Sbjct: 903 KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS 962 Query: 132 SGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182 GP P P A P PP + ++ P R G P LG Sbjct: 963 PGPVGPRGDPGAPGLPGPP-----------GKGKDGEPGLRGSPGLPGPLG 1002 Score = 27.7 bits (60), Expect = 6.5 Identities = 34/123 (27%), Positives = 38/123 (30%), Gaps = 17/123 (13%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G PG PGP G DG+ P A P RP L + GP+G Sbjct: 1497 GRPGP---PGPP----GKDGL---PGRAGPMGEPGRPGQGGLEGPSGPI------GPKGE 1540 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAP 147 G P P + RG P P P P P G P P P Sbjct: 1541 RGAK-GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP 1599 Query: 148 RPP 150 PP Sbjct: 1600 GPP 1602 >gi|7662302 TBK1 binding protein 1 [Homo sapiens] Length = 615 Score = 56.2 bits (134), Expect = 2e-08 Identities = 47/134 (35%), Positives = 64/134 (47%), Gaps = 13/134 (9%) Query: 47 GIRPAPAAA-HPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--R 103 G R +P + H PAP + P+ + + A P +SP PQ SP+PP P R Sbjct: 331 GQRHSPLSQRHSPAP-QCPSPSPPARAAPPCPPCQSPVPQR------RSPVPPCPSPQQR 383 Query: 104 GAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALA-APRPPLARPLPQGSVTA 162 +PA P+ PSP +P R S PP PS R +PPS A PRPP P + ++ Sbjct: 384 RSPASPSCPSP--VPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAE 441 Query: 163 REQEQRPRSRRRAG 176 R + P +AG Sbjct: 442 RAYAKPPSHHVKAG 455 Score = 39.3 bits (90), Expect = 0.002 Identities = 39/118 (33%), Positives = 47/118 (39%), Gaps = 13/118 (11%) Query: 68 RLSALAAAQPR--RRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP 125 RL L++ Q R R Q GG SP L R +PA P PSP P PAR + P Sbjct: 307 RLRELSSLQGRILRTLLQEQARSGGQRHSP----LSQRHSPA-PQCPSPSP-PARAAPPC 360 Query: 126 PRPSLPSGPHRPVLPPSALAAPR-----PPLARPLPQGSVTAREQEQRPRSRRRAGAP 178 P P R +PP R P P+PQ Q P +RR+ P Sbjct: 361 PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVP 418 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 55.5 bits (132), Expect = 3e-08 Identities = 48/139 (34%), Positives = 54/139 (38%), Gaps = 17/139 (12%) Query: 35 LPGPALVVAGLDGIRPAPAAAHPP--APRERPAAARLSALAAAQPRRR------------ 80 LP P L + PA A PP AP PA+ LS LA P+ Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440 Query: 81 SPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG--PLPARPSSPPPRPSLPSGPHRPV 138 SP P + P P + P P A PS PL PS P P PS P Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 139 LPPSALAAPRPPLARPLPQ 157 PP LAAP LA+P PQ Sbjct: 501 APPP-LAAPPLQLAKPPPQ 518 Score = 48.5 bits (114), Expect = 4e-06 Identities = 44/135 (32%), Positives = 53/135 (39%), Gaps = 34/135 (25%) Query: 53 AAAHPPAPRERPAAARLSALAAAQ--PRRRSPGPQGG--GGGDIASPLPPA-LQPRGAPA 107 A AHP P+ + L AL Q P R+ P G +A+P P A LQ + P Sbjct: 265 APAHPSQPKPKG----LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT 320 Query: 108 VPAAPSPG--------PLPARPSSPPPRPSLPSGPHRPVLPPSAL--------------- 144 +PA P PLP P SP PSL + P P PPS Sbjct: 321 LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380 Query: 145 --AAPRPPLARPLPQ 157 + P PLA P PQ Sbjct: 381 LPSPPLSPLATPPPQ 395 Score = 42.0 bits (97), Expect = 3e-04 Identities = 54/197 (27%), Positives = 71/197 (36%), Gaps = 37/197 (18%) Query: 19 AGRRVRVGVGEPGGFCLPGPALV----VAGLD-GI-RPAPAAA-HPPAPRERPAAARLSA 71 AG R PG P PA+ AG + G+ RPAP+A PP R + + S Sbjct: 158 AGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214 Query: 72 LAAAQPR---RRSPGPQGG-----------GGGDIASPLPPALQPRGAPAVPAAPS---- 113 + +P RR P GG ++SP RG P PA PS Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274 Query: 114 --------PGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLP-QGSVTARE 164 P P R + P L S P P +AL + PP P S+T + Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334 Query: 165 QEQRPRSRRRAGAPEAL 181 P + AP +L Sbjct: 335 ATPLPLAPPSPSAPPSL 351 Score = 42.0 bits (97), Expect = 3e-04 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 8/112 (7%) Query: 51 APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 +P A+ P +P P + +LAA + P A+P P A P AP + Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 111 APSPGPLPARPSSPPPRPSLPSGP-----HRPVLPPSALAAPRPPLARPLPQ 157 A P P ++PP + +LPS P P P ++L P PLA P PQ Sbjct: 513 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASL--PMSPLATPPPQ 561 Score = 40.0 bits (92), Expect = 0.001 Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 7/101 (6%) Query: 93 ASPLPPALQPRGAPAVPAAPSPGPLPAR----PSSPPPRPSLP---SGPHRPVLPPSALA 145 A P PPA P A P+ +P L P SPPP P + S P P + PSA Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466 Query: 146 APRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHA 186 + P + P V P S P+A P+ A Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 507 Score = 39.3 bits (90), Expect = 0.002 Identities = 53/153 (34%), Positives = 61/153 (39%), Gaps = 27/153 (17%) Query: 52 PAAAHPP--APRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P+ A PP P PA+ +S A P+ +P P A PL A P AP Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQ--APPPLA------APPLQLAKPPPQAPPAL 523 Query: 110 AAPSPGPLPARPSS-PPPRPSLPSGPHRPVLPPSALAAPRPP----LARPLPQ--GSVTA 162 A P LP+ P+S P P PS LP S LA P P LA PL Q S A Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579 Query: 163 REQEQRPRSRRRAGAPEALGPVHAGSDLELRLA 195 Q PR P GP + S L LA Sbjct: 580 SPTLQAPR------RPPTPGPDTSVSGPRLTLA 606 Score = 38.9 bits (89), Expect = 0.003 Identities = 48/162 (29%), Positives = 60/162 (37%), Gaps = 17/162 (10%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G G PGP G G+R + A A + A + SAL+A RR + GP G Sbjct: 118 GRASGTTRPGPL----GQKGLRIS--AEETVARGKATEAPKRSALSAGA-RRDTSGPTPG 170 Query: 88 GGGDIASPLPP-ALQPRGAPAVPAAPSPGPLPARPSSPP--PRPSLPSGPHRPVLPPSAL 144 +P P A + R A P P P ARP P PR S+ S PS Sbjct: 171 ------TPSPAMARRSRAAGTEVGLPRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPA 223 Query: 145 AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHA 186 A RP L + + + P S P A G A Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265 Score = 36.6 bits (83), Expect = 0.014 Identities = 41/154 (26%), Positives = 54/154 (35%), Gaps = 13/154 (8%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 PA GL + P P + P P PAA R+ A A R+ GG GG Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG------- 67 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSL-PSGPHRPVLPPSALAAP--RPPLARP 154 A P AP S G P+S PP P P +++P RP Sbjct: 68 -ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126 Query: 155 LPQGSVTAREQEQRPRSRRRAGAPEALGPVHAGS 188 P G R + +R +A + AG+ Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160 Score = 35.8 bits (81), Expect = 0.024 Identities = 44/154 (28%), Positives = 55/154 (35%), Gaps = 26/154 (16%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 PAL L + PA+ AP A+ +S LA +P PQ P Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA-------TPPPQA----------P 563 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPP--SALAAPRPPLARPL 155 P L AP + PSP PA P+ PR GP V P + AP PP P Sbjct: 564 PVL---AAPLLQVPPSP---PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPS 616 Query: 156 PQGSVTAREQEQRPRSRRRAGAPEALGPVHAGSD 189 S T + S PE L +G + Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 650 Score = 35.8 bits (81), Expect = 0.024 Identities = 33/97 (34%), Positives = 40/97 (41%), Gaps = 9/97 (9%) Query: 37 GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL 96 GP L +A G P P+ + P + P A S+ A + P G GG ASP Sbjct: 600 GPRLTLALAPGPPPPPSRS-PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658 Query: 97 PPALQPRGAPAVPAAPSPGPLP-----ARPSSPPPRP 128 P A A PAA S GP P P +P P P Sbjct: 659 PDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 692 Score = 30.8 bits (68), Expect = 0.76 Identities = 28/73 (38%), Positives = 31/73 (42%), Gaps = 2/73 (2%) Query: 105 APAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA-RPLPQGSVTAR 163 A PAA +PG L RP PRP P P + +A A R PLA R G T Sbjct: 13 AARTPAARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 164 EQEQRPRSRRRAG 176 E R R AG Sbjct: 72 ESAPRAGPTRSAG 84 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 55.5 bits (132), Expect = 3e-08 Identities = 48/139 (34%), Positives = 54/139 (38%), Gaps = 17/139 (12%) Query: 35 LPGPALVVAGLDGIRPAPAAAHPP--APRERPAAARLSALAAAQPRRR------------ 80 LP P L + PA A PP AP PA+ LS LA P+ Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 Query: 81 SPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG--PLPARPSSPPPRPSLPSGPHRPV 138 SP P + P P + P P A PS PL PS P P PS P Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 Query: 139 LPPSALAAPRPPLARPLPQ 157 PP LAAP LA+P PQ Sbjct: 462 APPP-LAAPPLQLAKPPPQ 479 Score = 50.4 bits (119), Expect = 9e-07 Identities = 40/117 (34%), Positives = 51/117 (43%), Gaps = 16/117 (13%) Query: 50 PAPAAAHPPAPR---ERPAAARLSALAA--AQPRRRSPGPQGGGGGDI--ASPLPPALQP 102 P+PAA P+ +RPA+ LS+ A + P R P +G + P P LQ Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270 Query: 103 RGAPAVP-----AAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARP 154 P V AAP+ GPL + P + P PS P P PPS P PP P Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPS----PSAPPSPSAPPSLQTLPSPPATPP 323 Score = 42.0 bits (97), Expect = 3e-04 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 8/112 (7%) Query: 51 APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 +P A+ P +P P + +LAA + P A+P P A P AP + Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473 Query: 111 APSPGPLPARPSSPPPRPSLPSGP-----HRPVLPPSALAAPRPPLARPLPQ 157 A P P ++PP + +LPS P P P ++L P PLA P PQ Sbjct: 474 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASL--PMSPLATPPPQ 522 Score = 40.0 bits (92), Expect = 0.001 Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 7/101 (6%) Query: 93 ASPLPPALQPRGAPAVPAAPSPGPLPAR----PSSPPPRPSLP---SGPHRPVLPPSALA 145 A P PPA P A P+ +P L P SPPP P + S P P + PSA Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427 Query: 146 APRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHA 186 + P + P V P S P+A P+ A Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 468 Score = 39.3 bits (90), Expect = 0.002 Identities = 53/153 (34%), Positives = 61/153 (39%), Gaps = 27/153 (17%) Query: 52 PAAAHPP--APRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P+ A PP P PA+ +S A P+ +P P A PL A P AP Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQ--APPPLA------APPLQLAKPPPQAPPAL 484 Query: 110 AAPSPGPLPARPSS-PPPRPSLPSGPHRPVLPPSALAAPRPP----LARPLPQ--GSVTA 162 A P LP+ P+S P P PS LP S LA P P LA PL Q S A Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540 Query: 163 REQEQRPRSRRRAGAPEALGPVHAGSDLELRLA 195 Q PR P GP + S L LA Sbjct: 541 SPTLQAPR------RPPTPGPDTSVSGPRLTLA 567 Score = 38.9 bits (89), Expect = 0.003 Identities = 48/162 (29%), Positives = 60/162 (37%), Gaps = 17/162 (10%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G G PGP G G+R + A A + A + SAL+A RR + GP G Sbjct: 109 GRASGTTRPGPL----GQKGLRIS--AEETVARGKATEAPKRSALSAGA-RRDTSGPTPG 161 Query: 88 GGGDIASPLPP-ALQPRGAPAVPAAPSPGPLPARPSSPP--PRPSLPSGPHRPVLPPSAL 144 +P P A + R A P P P ARP P PR S+ S PS Sbjct: 162 ------TPSPAMARRSRAAGTEVGLPRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPA 214 Query: 145 AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHA 186 A RP L + + + P S P A G A Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256 Score = 38.1 bits (87), Expect = 0.005 Identities = 53/190 (27%), Positives = 67/190 (35%), Gaps = 18/190 (9%) Query: 2 PGGVQAARFGAAVRGGGAGRR-VRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAH---- 56 P V A G GR+ + G GG +P A RP PA+ Sbjct: 36 PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP-PASGRGERA 94 Query: 57 PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPA------LQPRGAPAVPA 110 PPA P A+ R PGP G G I++ A R A + A Sbjct: 95 PPAKNTSPGPVSSPGRASGTTR---PGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151 Query: 111 A-PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQ--EQ 167 + GP P PS R S +G + P+ A PRPP P S + E Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211 Query: 168 RPRSRRRAGA 177 P +RRR A Sbjct: 212 SPAARRRPSA 221 Score = 36.6 bits (83), Expect = 0.014 Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 18/152 (11%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 PA GL + P P + P P PAA R+ A A R+ GG GG Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG------- 67 Query: 98 PALQPRGAP-AVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLP 156 A P AP A P S P R PP + G PV P + RP P Sbjct: 68 -ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPG---PVSSPGRASG----TTRPGP 119 Query: 157 QGSVTAREQEQRPRSRRRAGAPEALGPVHAGS 188 G R + +R +A + AG+ Sbjct: 120 LGQKGLRISAEETVARGKATEAPKRSALSAGA 151 Score = 35.8 bits (81), Expect = 0.024 Identities = 44/154 (28%), Positives = 55/154 (35%), Gaps = 26/154 (16%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 PAL L + PA+ AP A+ +S LA +P PQ P Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA-------TPPPQA----------P 524 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPP--SALAAPRPPLARPL 155 P L AP + PSP PA P+ PR GP V P + AP PP P Sbjct: 525 PVL---AAPLLQVPPSP---PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPS 577 Query: 156 PQGSVTAREQEQRPRSRRRAGAPEALGPVHAGSD 189 S T + S PE L +G + Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611 Score = 35.8 bits (81), Expect = 0.024 Identities = 33/97 (34%), Positives = 40/97 (41%), Gaps = 9/97 (9%) Query: 37 GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL 96 GP L +A G P P+ + P + P A S+ A + P G GG ASP Sbjct: 561 GPRLTLALAPGPPPPPSRS-PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619 Query: 97 PPALQPRGAPAVPAAPSPGPLP-----ARPSSPPPRP 128 P A A PAA S GP P P +P P P Sbjct: 620 PDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653 Score = 28.9 bits (63), Expect = 2.9 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 2/75 (2%) Query: 105 APAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA-RPLPQGSVTAR 163 A PAA +PG L RP PRP P P + +A A R PLA R G T Sbjct: 13 AARTPAARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 164 EQEQRPRSRRRAGAP 178 E R R + P Sbjct: 72 ESAPRAGPTRTSRPP 86 >gi|33286436 gametogenetin [Homo sapiens] Length = 652 Score = 55.5 bits (132), Expect = 3e-08 Identities = 66/207 (31%), Positives = 81/207 (39%), Gaps = 31/207 (14%) Query: 9 RFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPP-----APRE- 62 RF A G GA RR + P G P P + + RPAPA PP AP Sbjct: 365 RFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG 424 Query: 63 ---RPAAARLSALAAAQPRRRSPGPQGGGGGD----IASPLPP-------ALQPRGAPAV 108 RP L L P P Q +A PL P AL P APA+ Sbjct: 425 EPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPAL 484 Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQR 168 P A + PA SP P P++ + P PV P+ AAP R +GS AR ++ Sbjct: 485 PPALAADQAPA--PSPAPAPTV-AEPSPPVSAPAPAAAPIKTRTR-RNKGSRAARGATRK 540 Query: 169 -------PRSRRRAGAPEALGPVHAGS 188 PR R A P++ G GS Sbjct: 541 DGLHGDGPRERATATVPDSSGGGGGGS 567 Score = 42.7 bits (99), Expect = 2e-04 Identities = 47/153 (30%), Positives = 55/153 (35%), Gaps = 21/153 (13%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPR--ERPAAARLSALAAAQPRRRSPGPQGGGGGDIAS- 94 P A + PAPA P P ++PA + + RR G GD S Sbjct: 86 PPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRI------RRLLEASHRGQGDPPSL 139 Query: 95 ----PLPPALQPRGAPAVPAAPSPGPLPARP-SSPPPRPSLPSGPHRPVLPPSALAAPRP 149 P PP Q VP APS P P PPP PS R + P ALA P Sbjct: 140 RPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITP--ALATPAS 197 Query: 150 PLARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182 P P S + + R R GAP G Sbjct: 198 P-----PTESQAGPRNQGQTAGRARGGAPPHAG 225 Score = 28.9 bits (63), Expect = 2.9 Identities = 30/107 (28%), Positives = 39/107 (36%), Gaps = 19/107 (17%) Query: 52 PAAAHPPA---PRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAV 108 P +A PP PRE A+ L +P P P+ +++P P APA Sbjct: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAA--VSAPPP-------APAG 102 Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPL 155 P P +P PR R +L S PP RPL Sbjct: 103 TLLPGPSKWQKPAGTPVPRI-------RRLLEASHRGQGDPPSLRPL 142 Score = 28.9 bits (63), Expect = 2.9 Identities = 36/124 (29%), Positives = 43/124 (34%), Gaps = 10/124 (8%) Query: 64 PAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSS 123 P AAR ++ + + G G G G P PA Q R P P PG P Sbjct: 296 PGAARPLG-EVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKF--- 351 Query: 124 PPPRPSLPSGPHRPVLPPSA---LAAP-RPPLARPLPQGSVTAREQEQRPRSRRRAGAPE 179 S P GP R A + AP R A P GS ++ R AP Sbjct: 352 --DWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPA 409 Query: 180 ALGP 183 L P Sbjct: 410 LLAP 413 Score = 28.5 bits (62), Expect = 3.8 Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 17/94 (18%) Query: 104 GAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPP----SALAAPRPPLARPL---- 155 G+ P P A PS+ P PS PV+PP +A++AP P A L Sbjct: 53 GSATPPGLMVPREPQASPSTLPLTLERPS----PVMPPPEEAAAVSAPPPAPAGTLLPGP 108 Query: 156 -----PQGSVTAREQEQRPRSRRRAGAPEALGPV 184 P G+ R + S R G P +L P+ Sbjct: 109 SKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPL 142 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 55.1 bits (131), Expect = 4e-08 Identities = 50/147 (34%), Positives = 62/147 (42%), Gaps = 12/147 (8%) Query: 7 AARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAA 66 AAR G G G G G G+P G PG A + G + + AA P Sbjct: 167 AARAGPGP-GPGPGPGPGPGPGKPAG---PGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222 Query: 67 ARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPP 126 A L L P+ +PG + + PPA AP+ PAAP+P A P PPP Sbjct: 223 AALLPL----PKPAAPGTVIQTPPFVGAAAPPA---PAAPSPPAAPAPAAPAAAPPPPPP 275 Query: 127 RP-SLPSGPHRPVLPPSALAAPRPPLA 152 P +L P P PP+A A PP A Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPPAA 302 Score = 54.3 bits (129), Expect = 6e-08 Identities = 50/172 (29%), Positives = 57/172 (33%), Gaps = 48/172 (27%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRR------- 80 G P G GPA G G P P PPA R RP PRR Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEP----PPAGRARPGGGGPQRPGPPSPRRPLVPAGPA 120 Query: 81 ------SPGPQGGGGGDIASPLPPALQ----PRGAPAVPAAPS----------PGPLPAR 120 P P+G G +P+P A P APA PA P+ PGP P Sbjct: 121 PPAAKLRPPPEGSAGS--CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178 Query: 121 PSSPPPRPSLPSGP---------------HRPVLPPSALAAPRPPLARPLPQ 157 P P P P+GP H P +L P PLP+ Sbjct: 179 GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230 Score = 50.1 bits (118), Expect = 1e-06 Identities = 44/138 (31%), Positives = 53/138 (38%), Gaps = 12/138 (8%) Query: 51 APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP--PALQPRGAPAV 108 A +AAH R R +A A S P G G A+P P P PA Sbjct: 34 AASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAG 93 Query: 109 PAAPSPGPLPARPSSPPPR-PSLPSGPHRPVLPPSALAAPRPP----LARPLPQGSVTAR 163 A P G P RP P PR P +P+GP PP+A P P P+P + A Sbjct: 94 RARPGGGG-PQRPGPPSPRRPLVPAGP----APPAAKLRPPPEGSAGSCAPVPAAAAVAA 148 Query: 164 EQEQRPRSRRRAGAPEAL 181 E P + P AL Sbjct: 149 GPEPAPAGPAKPAGPAAL 166 Score = 47.8 bits (112), Expect = 6e-06 Identities = 67/201 (33%), Positives = 73/201 (36%), Gaps = 62/201 (30%) Query: 32 GFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGD 91 G C P PA G PAPA PA PAA A A P PGP G G G Sbjct: 135 GSCAPVPAAAAVAA-GPEPAPAGPAKPAG---PAALA----ARAGP---GPGP-GPGPGP 182 Query: 92 IASPLPPA----------------LQPRGAPAV------PAAPSPGPLPARP-------- 121 P PA APAV PAA P P PA P Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242 Query: 122 ---SSPPPRPSLPSGPHRPVLPPSALAAPRPP------LARP--LPQGSVTAREQEQRPR 170 ++ PP P+ PS P P P + AAP PP LARP P G TA P Sbjct: 243 FVGAAAPPAPAAPSPPAAPA-PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301 Query: 171 SRRRAG--------APEALGP 183 + + G AP A GP Sbjct: 302 AAQNGGSAGAAPAPAPAAGGP 322 Score = 42.0 bits (97), Expect = 3e-04 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 13/115 (11%) Query: 50 PAPAAAHPPAPRE--RPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 PAPAA PPA PAAA A R PG G + PPA G A Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA 309 Query: 108 VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 AAP+P P P+ +P P +A AAP P + P+ V A Sbjct: 310 -GAAPAPAPAAGGPAGVSGQPG----------PGAAAAAPAPGVKAESPKRVVQA 353 Score = 40.8 bits (94), Expect = 7e-04 Identities = 47/136 (34%), Positives = 52/136 (38%), Gaps = 18/136 (13%) Query: 50 PAPAA-AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAV 108 PA AA A P AP E A P G GGG P PP+ PR P V Sbjct: 67 PAGAAGAGPAAPAE--------GAPGAAPEPPPAGRARPGGGGPQRPGPPS--PR-RPLV 115 Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA-PRPPLARPLPQGSVTAREQEQ 167 PA P+P PA PPP S +G PV +A+AA P P A P A Sbjct: 116 PAGPAP---PAAKLRPPPEGS--AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170 Query: 168 RPRSRRRAGAPEALGP 183 P G GP Sbjct: 171 GPGPGPGPGPGPGPGP 186 Score = 40.4 bits (93), Expect = 0.001 Identities = 48/150 (32%), Positives = 53/150 (35%), Gaps = 20/150 (13%) Query: 36 PGPALVVAGLDGIRPAPAA-AHPP---------APRERPAAARL---SALAAAQPRRRSP 82 P PA A PAPA A PP AP P AA SA AA P + Sbjct: 261 PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320 Query: 83 GPQG-----GGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRP 137 GP G G G A+P P V AAP A S+ GP Sbjct: 321 GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQ 380 Query: 138 VLPPSALAAPRPPLARP--LPQGSVTAREQ 165 PS A P P P LP+G+ A Q Sbjct: 381 GALPSPAAVPPPAPGTPTGLPKGAAGAVTQ 410 Score = 35.8 bits (81), Expect = 0.024 Identities = 45/187 (24%), Positives = 63/187 (33%), Gaps = 22/187 (11%) Query: 2 PG-GVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGL------DGIRPAPAA 54 PG G AA V+ R V+ GPA A + G P+PAA Sbjct: 329 PGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAA 388 Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPS- 113 PPAP + +A A Q R+P G I + L P + P P P+ Sbjct: 389 VPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSG---IRATLTPTVLAPRLPQPPQNPTN 445 Query: 114 -------PGPLPARPSSPP----PRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 PG + R + P+ +L + P APRP P ++ Sbjct: 446 IQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST 505 Query: 163 REQEQRP 169 + P Sbjct: 506 VQAPGTP 512 >gi|22027541 programmed cell death 7 [Homo sapiens] Length = 485 Score = 55.1 bits (131), Expect = 4e-08 Identities = 51/158 (32%), Positives = 57/158 (36%), Gaps = 34/158 (21%) Query: 50 PAPAAAHPPAPRERP------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPR 103 P P+ A PP +RP +A L A QPR + +GGGG P+PP P Sbjct: 31 PLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAFYPVPP--PPL 88 Query: 104 GAPAVPAAPSPG-PLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 P P PG RP PPP P P P P PP P V Sbjct: 89 PPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPP--------------PPADVLG 134 Query: 163 REQEQRPRSR----------RRAGAPEALGPVHAGSDL 190 QR R R RRAG P HAG L Sbjct: 135 DAALQRLRDRQWLEAVFGTPRRAGCP-VPQRTHAGPSL 171 Score = 39.3 bits (90), Expect = 0.002 Identities = 31/106 (29%), Positives = 35/106 (33%), Gaps = 14/106 (13%) Query: 76 QPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLP---- 131 Q R P PQ P PP P P +P P P P + P PP P Sbjct: 9 QGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASA 68 Query: 132 --------SGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRP 169 +G PV PP P PP RP P R + P Sbjct: 69 EASRGGGGAGAFYPVPPPP--LPPPPPQCRPFPGTDAGERPRPPPP 112 Score = 33.5 bits (75), Expect = 0.12 Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 3/79 (3%) Query: 99 ALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQG 158 AL P P P P P P P PP P LPS P LP P P + P Q Sbjct: 2 ALPPFFGQGRPGPPPPQPPPPAPFGCPP-PPLPSPAFPPPLPQR--PGPFPGASAPFLQP 58 Query: 159 SVTAREQEQRPRSRRRAGA 177 + + + SR GA Sbjct: 59 PLALQPRASAEASRGGGGA 77 >gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] Length = 1489 Score = 53.9 bits (128), Expect = 8e-08 Identities = 56/160 (35%), Positives = 64/160 (40%), Gaps = 28/160 (17%) Query: 16 GGGAGRRVRVGVG----EPGGFCLP---GPALVVAGLDGIRPAPAAAHPPAPRERPAAAR 68 GGG RR + E CLP G A VAG G PA HPP A R Sbjct: 687 GGGPSRRGPLPCPLCSREGACSCLPLERGDA--VAGWGG-HPALGCPHPPEDDSSLRAER 743 Query: 69 --LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPP 126 L+ L A P AS P L P A P P GP PA P PPP Sbjct: 744 GSLADLPMAPP---------------ASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPP 788 Query: 127 RPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQE 166 P P+ P PPSA+A+P L+ P P+ + E E Sbjct: 789 -PRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETE 827 Score = 45.1 bits (105), Expect = 4e-05 Identities = 44/142 (30%), Positives = 50/142 (35%), Gaps = 30/142 (21%) Query: 6 QAARFGAAVRGGGAGR-------RVRVGVGE-PGGFCLPGPALVVAGLDGIRPAPAAAHP 57 +A G A R GAGR R VG G PGG G +D RP P P Sbjct: 1120 RAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQP----P 1175 Query: 58 PAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPL 117 P P P A QPRR P P P + P G P P + + G Sbjct: 1176 PPPLPPPPEA--------QPRRLEPAPPRAR---------PEVAPEGEPGAPDSRAGGDT 1218 Query: 118 PARPSSPPPRPSLPSGPHRPVL 139 PP+P GP P L Sbjct: 1219 ALSGDGDPPKPE-RKGPEMPRL 1239 Score = 36.6 bits (83), Expect = 0.014 Identities = 51/186 (27%), Positives = 63/186 (33%), Gaps = 31/186 (16%) Query: 13 AVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLS-- 70 A RG A + P F P G P PA PP P PA S Sbjct: 741 AERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPD 800 Query: 71 ---ALAAAQPRRRSPGPQGGGGG-DIASPLPP--------------ALQPRGAPAVPAAP 112 A+A+ SPGP+ G G + +P P +PR P P Sbjct: 801 PPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPG 860 Query: 113 SPGPLPARPSSPPPRPSLPSGPHRP-----VLPPSALAAPRPPLARP-LPQGSVTAREQE 166 +P P P P P P LP +P V L + R + R L + TARE Sbjct: 861 APRP----PPDPGPLP-LPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETG 915 Query: 167 QRPRSR 172 R R Sbjct: 916 PRKAGR 921 Score = 35.4 bits (80), Expect = 0.031 Identities = 48/175 (27%), Positives = 59/175 (33%), Gaps = 29/175 (16%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRE---RPAAARLSALAAAQPRRRSPGPQGGGGGDI 92 P P+ VV+ +G AP P AP+ P R + PR G G G Sbjct: 1085 PAPSAVVSSRNGGETAPGPLGP-APKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGR 1143 Query: 93 ASPLPPALQPRGAPA------------VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLP 140 A P+ P G P P P PLP P + P R RP + Sbjct: 1144 A-PVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVA 1202 Query: 141 PSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA------LGPVHAGSD 189 P P P +R G TA + P R G PE LGP S+ Sbjct: 1203 PE--GEPGAPDSR---AGGDTALSGDGDPPKPERKG-PEMPRLFLDLGPPQGNSE 1251 Score = 29.6 bits (65), Expect = 1.7 Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Query: 117 LPARPSSPPPRPSLPSGPHRPVLPPSALAAPRP-PLARPLP 156 L RP PPP P P P P A +APRP L+ P P Sbjct: 441 LSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFP 481 Score = 28.9 bits (63), Expect = 2.9 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 7/62 (11%) Query: 60 PRERPAAA----RLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG 115 P +RP+A+ +L+ L + +P R P P G P PPA AP SP Sbjct: 424 PAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPA---HSAPRPGTLSSPF 480 Query: 116 PL 117 PL Sbjct: 481 PL 482 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 53.5 bits (127), Expect = 1e-07 Identities = 46/137 (33%), Positives = 51/137 (37%), Gaps = 14/137 (10%) Query: 15 RGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAA 74 RG G R V P P PA + G P P A PPAP P + Sbjct: 282 RGSGLAGPKRSSVVSPSH---PPPAPPLGSPPG--PKPGFAPPPAPPPPPPPM----IGI 332 Query: 75 AQPRRRSPGPQG-GGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG 133 P P P G G G P PP+ P A P P P P P+ PPP S P+G Sbjct: 333 PPP----PPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTG 388 Query: 134 PHRPVLPPSALAAPRPP 150 P PP P PP Sbjct: 389 GAPPPPPPPPPPGPPPP 405 Score = 47.4 bits (111), Expect = 8e-06 Identities = 43/139 (30%), Positives = 54/139 (38%), Gaps = 28/139 (20%) Query: 46 DGIRPAPAAAHPPAPRERP---AAARLSALAA------AQPRRRSPGPQGGGGGDIASPL 96 D + P PA P +R A + S++ + A P PGP+ G A P Sbjct: 265 DNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPP 324 Query: 97 PP----ALQPR------GAPAVPAAPSPGPLPARP---SSPPPRPSLPSGPHRPVLPPSA 143 PP + P G+P P PSP P P + PPP P P P LPP Sbjct: 325 PPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPP--PPAADYPTLPPPP 382 Query: 144 LAAPR----PPLARPLPQG 158 L+ P PP P P G Sbjct: 383 LSQPTGGAPPPPPPPPPPG 401 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 53.1 bits (126), Expect = 1e-07 Identities = 40/113 (35%), Positives = 43/113 (38%), Gaps = 27/113 (23%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P P A+ PP P P P G G A P+PP G P P Sbjct: 646 PPPPASIPPPP---------------------PLPSGLGSLSPAPPMPPV--SAGPPLPP 682 Query: 110 AAPSPGPLP----ARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQG 158 P P PLP A P PPP P LP+ P P A P P LA P P G Sbjct: 683 PPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735 Score = 41.2 bits (95), Expect = 6e-04 Identities = 39/126 (30%), Positives = 48/126 (38%), Gaps = 29/126 (23%) Query: 35 LPGPALVVAGLDGIRPAP----AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90 +P P + +GL + PAP +A PP P P L ++A P P P Sbjct: 652 IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGP----PPP------ 701 Query: 91 DIASPLPPALQPRGAPAVPAAPSPGPLP-ARPSSPPPRPSLPSG--------PHRPVLPP 141 P PP L AP P P P P P PPP P L G P +P + P Sbjct: 702 ----PPPPPLPNSPAPPNPGGPPPAPPPPGLA--PPPPPGLFFGLGSSSSQCPRKPAIEP 755 Query: 142 SALAAP 147 S P Sbjct: 756 SCPMKP 761 Score = 39.7 bits (91), Expect = 0.002 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 14/86 (16%) Query: 69 LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP 128 + +A+ Q + P P AS PP P G ++ AP P+ A P PPP P Sbjct: 634 MEGMASNQQKALPPPP--------ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP 685 Query: 129 SLPSGPHRPVLPPSALAAPRPPLARP 154 P LPP + A P PP P Sbjct: 686 PPPP------LPPPSSAGPPPPPPPP 705 Score = 38.9 bits (89), Expect = 0.003 Identities = 29/73 (39%), Positives = 32/73 (43%), Gaps = 9/73 (12%) Query: 92 IASPLPPALQPRGAPAVPAAPSPGPL----PARPSSP----PPRPSLPSGPHRPVLPPSA 143 +AS AL P A P P P L PA P P PP P P P P+ PPS+ Sbjct: 637 MASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP-PPPPPPPLPPPSS 695 Query: 144 LAAPRPPLARPLP 156 P PP PLP Sbjct: 696 AGPPPPPPPPPLP 708 Score = 37.7 bits (86), Expect = 0.006 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 3/104 (2%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 P G PA + + P P PP P P++A P SP P GG Sbjct: 659 PSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718 Query: 90 GDIASPLPPALQPRGAPAV--PAAPSPGPLPARPSSPPPRPSLP 131 A P PP L P P + S P +P+ P P P Sbjct: 719 PPPAPP-PPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761 Score = 34.7 bits (78), Expect = 0.053 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%) Query: 101 QPRGAPAVPAA-PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS 159 Q + P PA+ P P PLP+ S P P +P P LPP PP PLP S Sbjct: 641 QQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPP------PPPPPPLPPPS 694 Score = 33.5 bits (75), Expect = 0.12 Identities = 23/59 (38%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 99 ALQPRGAPAVPAAPSPGPLPARPSSPPPRPS-LPSGPHRPVLPPSALAAPRPPLARPLP 156 ALQP A + P PA PPP PS L S P +PP + P PP P P Sbjct: 630 ALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 53.1 bits (126), Expect = 1e-07 Identities = 47/135 (34%), Positives = 50/135 (37%), Gaps = 13/135 (9%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG LP P L AG+ P P AA PP P P L P P P G Sbjct: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPP---PLPGAGIPLPPPLPGAGIPPPPPLPG 983 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP----PPRPSLPSGPHRPVLPPSALA 145 I P PP L G P P P G +P P P PP P LP P P Sbjct: 984 AGI--PPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040 Query: 146 APRPPLARPLPQGSV 160 P PP PLP + Sbjct: 1041 IPPPP---PLPGAGI 1052 Score = 51.2 bits (121), Expect = 5e-07 Identities = 46/134 (34%), Positives = 50/134 (37%), Gaps = 22/134 (16%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ + P P A PP P P AA P P P G G Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPP---PLPG-----AAIPP----PPPLPGAG 963 Query: 90 GDIASPLPPALQPRGAPAVPAAPS---PGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146 PLPP L G P P P P P P + PP P LP P P Sbjct: 964 ----IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019 Query: 147 PRPPLARPLPQGSV 160 P PP PLP + Sbjct: 1020 PPPP---PLPGAGI 1030 Score = 48.5 bits (114), Expect = 4e-06 Identities = 43/131 (32%), Positives = 48/131 (36%), Gaps = 5/131 (3%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRP 149 PLP A P P +P A P P P + PP P LP P P + P P Sbjct: 1052 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110 Query: 150 PLARPLPQGSV 160 P PLP + Sbjct: 1111 P---PLPGAGI 1118 Score = 47.0 bits (110), Expect = 1e-05 Identities = 46/140 (32%), Positives = 51/140 (36%), Gaps = 18/140 (12%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P P P P G Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1071 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP----PPRPSLPSG--PHRPVLPPSA 143 I P PP L G P P P G +P P P PP P LP P P LP + Sbjct: 1072 AGI--PPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128 Query: 144 LAAPRP------PLARPLPQ 157 + P P P PLP+ Sbjct: 1129 IPPPPPLPGAGIPPPPPLPR 1148 Score = 46.2 bits (108), Expect = 2e-05 Identities = 45/124 (36%), Positives = 48/124 (38%), Gaps = 5/124 (4%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117 Query: 90 GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAP 147 PLP A P P +P A P P PLP R PPP P +G P P A P Sbjct: 1118 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP-RVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175 Query: 148 RPPL 151 PPL Sbjct: 1176 PPPL 1179 Score = 45.8 bits (107), Expect = 2e-05 Identities = 43/134 (32%), Positives = 46/134 (34%), Gaps = 11/134 (8%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P P P P G Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1060 Query: 90 GDIASPLPPALQPRGAPAVPAAPS---PGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146 I P PP L G P P P P P P + PP P LP P P Sbjct: 1061 AGI--PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118 Query: 147 PRPPLARPLPQGSV 160 P PP PLP + Sbjct: 1119 PPPP---PLPGAGI 1129 Score = 45.8 bits (107), Expect = 2e-05 Identities = 47/136 (34%), Positives = 51/136 (37%), Gaps = 11/136 (8%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P PP P P P P P G Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1181 Query: 90 GDIASPLP-PALQPRGAPAVPAA--PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146 I P P P + P +P A P P PLP P P P LP P + PP L Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP-PGTGIPPPPLLPV 1240 Query: 147 PRPPLARPLPQ-GSVT 161 PPL LPQ GS T Sbjct: 1241 SGPPL---LPQVGSST 1253 Score = 45.1 bits (105), Expect = 4e-05 Identities = 44/138 (31%), Positives = 48/138 (34%), Gaps = 16/138 (11%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P P P P G Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1104 Query: 90 GDIASPLPPALQPRGAPAVP-----AAPSPGPLPAR---PSSPPPRPSLPSGPHRP---V 138 + P PP L G P P P P PLP P P PR +P P P + Sbjct: 1105 --VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162 Query: 139 LPPSALAAPRPPLARPLP 156 PP L P PLP Sbjct: 1163 PPPPPLPGAGIPPPPPLP 1180 Score = 44.3 bits (103), Expect = 7e-05 Identities = 43/135 (31%), Positives = 47/135 (34%), Gaps = 13/135 (9%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P PP P P P P P G Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1137 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP----PPRPSLPSGPHRPVLPPSALA 145 I P PP L G P P P G +P P P PP P LP P P + Sbjct: 1138 AGI--PPPPPLPRVGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194 Query: 146 APRPPLARPLPQGSV 160 P PP PLP + Sbjct: 1195 IPPPP---PLPGAGI 1206 Score = 43.5 bits (101), Expect = 1e-04 Identities = 33/107 (30%), Positives = 37/107 (34%), Gaps = 11/107 (10%) Query: 57 PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116 PP P P P P P G ++ P PP L G P P P G Sbjct: 877 PPPPPPLPGMT-----VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931 Query: 117 LPARP---SSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSV 160 LP P + PP P LP P P P PP PLP + Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP---PLPGAGI 975 Score = 41.6 bits (96), Expect = 4e-04 Identities = 42/134 (31%), Positives = 46/134 (34%), Gaps = 26/134 (19%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P PP P P P P G Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP--------------PLPGVGIPPPPPLPG 1203 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPR- 148 I P PP L G P PA P P P PPP + P P + S L P+ Sbjct: 1204 AGI--PPPPPLPGMGIPPAPAPPLPPP--GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259 Query: 149 ----PPLARPLPQG 158 PP PLP G Sbjct: 1260 CGFLPP---PLPSG 1270 Score = 40.8 bits (94), Expect = 7e-04 Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 2/114 (1%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 P + LD +P + + PP P +A + P S Q ++S Sbjct: 791 PRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK 850 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPL 151 + P +P S +P PPP P LP G P LP +A+ P PPL Sbjct: 851 NSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP-GMTVPTLPSTAIPQP-PPL 902 Score = 39.3 bits (90), Expect = 0.002 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 3/66 (4%) Query: 89 GGDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPRPSLPSGPHRPVLP-PSALA 145 G + P PP L P +P+ P P PL PPP P LP P P P A Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931 Query: 146 APRPPL 151 P PPL Sbjct: 932 LPLPPL 937 Score = 33.5 bits (75), Expect = 0.12 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 8/91 (8%) Query: 44 GLDGIRPAPAAAHPPAPRERPAAARLSALA------AAQPRRRSPGPQGGGGGDIASPLP 97 GLD P+ AP LSAL+ AA+PR P GG +P Sbjct: 248 GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL 307 Query: 98 PALQP--RGAPAVPAAPSPGPLPARPSSPPP 126 PA QP + +P+ A P P P ++ P Sbjct: 308 PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338 Score = 32.7 bits (73), Expect = 0.20 Identities = 32/125 (25%), Positives = 41/125 (32%), Gaps = 14/125 (11%) Query: 83 GPQGGGGGDIASP-----------LPPAL--QPRGAPAVPAAPSPGPLPARPSSPPPRPS 129 GP GG G SP LP +L +PR P P +P P+ PS P +P+ Sbjct: 255 GPSGGAGEAPGSPDTEQALSALSDLPESLAAEPR-EPQQPPSPGGLPVSEAPSLPAAQPA 313 Query: 130 LPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHAGSD 189 P P P+ T E E+ G+P G D Sbjct: 314 AKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGED 373 Query: 190 LELRL 194 RL Sbjct: 374 APQRL 378 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 52.8 bits (125), Expect = 2e-07 Identities = 42/117 (35%), Positives = 52/117 (44%), Gaps = 16/117 (13%) Query: 50 PAPAAAHP--PAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIA-SPLP-PALQPRGA 105 P PA+A P P P PA A LS +A P P + +P+P P L P A Sbjct: 284 PVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPA 343 Query: 106 PAVPAAPSPGPLPARPSSPPPRPSLPSGPHR-----PVLPPSALAAPRP-PLARPLP 156 PAAP+P PS P P P+ SGP P P+ + AP P P+ P P Sbjct: 344 STPPAAPAP------PSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAP 394 Score = 38.9 bits (89), Expect = 0.003 Identities = 51/172 (29%), Positives = 62/172 (36%), Gaps = 43/172 (25%) Query: 24 RVGVGEPGGFCLP--GPALVVAGL-----DGIRPAPAAAHPPAPRERPAAARLSALAAAQ 76 R GVGE F L G + V G P PA PPAP A+ S A Q Sbjct: 165 RQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGS--ASVPHSVPDAFQ 222 Query: 77 PRRRSPGPQGGGG---GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP-------- 125 P P G +A+ +P AP+ P AP P PA PS P Sbjct: 223 VPLSVPAPVPHSGLVPVQVATSVP-------APSPPLAPVPALAPAPPSVPTLISDSNPL 275 Query: 126 ----------PRPSLPSGP---HRPVLPPSALAAPRPPLA---RPLPQGSVT 161 P + PSGP P P ++ PPLA P+P + T Sbjct: 276 SVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPT 327 Score = 38.9 bits (89), Expect = 0.003 Identities = 34/123 (27%), Positives = 43/123 (34%), Gaps = 2/123 (1%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASP 95 P AL+ A + P A P P P A A A P P P G Sbjct: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPT 371 Query: 96 LPPALQPRGAPAVPAAP--SPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR 153 L PA P PA AP +P P P ++P P+ P L A + P + Sbjct: 372 LIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQ 431 Query: 154 PLP 156 +P Sbjct: 432 KVP 434 Score = 36.6 bits (83), Expect = 0.014 Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 10/137 (7%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 P F +P G+ P A PAP P A + ALA A P + Sbjct: 218 PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS--PPLAPVPALAPAPPSVPTLISDSNPL 275 Query: 90 GDIASPLPPALQPRGAPAVPAAPSP--GPLPARPSSPPPRP--SLPSGPHRPVLPPSALA 145 AS L P P AP P+ P P P PA S P P +L P P P LA Sbjct: 276 SVSASVLVPV--PASAP--PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLA 331 Query: 146 APRPPLARPLPQGSVTA 162 P+ P+P + A Sbjct: 332 PVPTPVLAPMPASTPPA 348 Score = 34.3 bits (77), Expect = 0.069 Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 25/173 (14%) Query: 34 CLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRS---PGPQGGGGG 90 CLPG L L A + A P + + ++ L P + P P G Sbjct: 489 CLPG-VLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDG---- 543 Query: 91 DIASPLPPALQPRGAPAVPAAPSPG-PLPARPSSPPPRPSLPSGPHR----------PVL 139 + PL + V P P P P+ S+PP +PSG + P+ Sbjct: 544 -VPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLK 602 Query: 140 PPSAL----AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHAGS 188 P L A+P PL S + R++ P R+ P L PVH S Sbjct: 603 SPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMP-VLTPVHTSS 654 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 52.8 bits (125), Expect = 2e-07 Identities = 48/154 (31%), Positives = 60/154 (38%), Gaps = 31/154 (20%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P PA PAP PA A A AA + R S P P P + + +P Sbjct: 505 PTPATTPAPAPAPAPAPAPALASAATKERTESEVP----------PRPASPKVTRSPPET 554 Query: 110 AAP-------SPGPLPARPSSPPPRPS-LPSGPHRPVLPPSALAAPRPPLARP------- 154 AAP + P PARP+ PPP+ S S P P LPP + +P P A P Sbjct: 555 AAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGS-GSPGTPQALPRRLVGSS 613 Query: 155 -----LPQGSVTAREQEQRPRSRRRAGAPEALGP 183 +P Q R +SRR +P P Sbjct: 614 LRAPTVPPPLPPTPPQPARRQSRRSPASPSPASP 647 Score = 43.9 bits (102), Expect = 9e-05 Identities = 47/164 (28%), Positives = 58/164 (35%), Gaps = 18/164 (10%) Query: 36 PGPALVVAGL-----DGIRPAPAAAHPPAPRERPAAA--------RLSALAAAQPRRRSP 82 P PAL A + P PA+ P R P A R A A+P P Sbjct: 521 PAPALASAATKERTESEVPPRPAS--PKVTRSPPETAAPVEDMARRTKRPAPARPTMPPP 578 Query: 83 GPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHR--PVLP 140 G A PLPP G P G P+ PPP P P P R Sbjct: 579 QVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRS 638 Query: 141 PSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPV 184 P++ + P A P P S++ Q + GAPEA+ V Sbjct: 639 PASPSPASPGPASPSPV-SLSNPAQVDLGAATAEGGAPEAISGV 681 Score = 39.7 bits (91), Expect = 0.002 Identities = 39/132 (29%), Positives = 52/132 (39%), Gaps = 19/132 (14%) Query: 52 PAAAHPPAPRERPAAARLSALAAA-QPRRRSPG-----PQGGGGGDIASP-LPPALQP-- 102 PA A P P + + +R S A P SPG P+ G + +P +PP L P Sbjct: 568 PAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTP 627 Query: 103 --------RGAPAVPAAPSPGPLPARPSS--PPPRPSLPSGPHRPVLPPSALAAPRPPLA 152 R +PA P+ SPGP P S P + L + P + P PP Sbjct: 628 PQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAI 687 Query: 153 RPLPQGSVTARE 164 P P+ A E Sbjct: 688 PPQPRPRSLASE 699 Score = 36.6 bits (83), Expect = 0.014 Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 8/84 (9%) Query: 51 APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 AP P P A R S + A P SPGP ASP P +L + A Sbjct: 616 APTVPPPLPPTPPQPARRQSRRSPASPSPASPGP--------ASPSPVSLSNPAQVDLGA 667 Query: 111 APSPGPLPARPSSPPPRPSLPSGP 134 A + G P S P P++P P Sbjct: 668 ATAEGGAPEAISGVPTPPAIPPQP 691 Score = 31.6 bits (70), Expect = 0.45 Identities = 36/124 (29%), Positives = 42/124 (33%), Gaps = 37/124 (29%) Query: 96 LPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG----------PHRPVLP----- 140 LP P PA AP+P P PA P P+L S P RP P Sbjct: 499 LPSTAVP--TPATTPAPAPAPAPA------PAPALASAATKERTESEVPPRPASPKVTRS 550 Query: 141 PSALAAP--------------RPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHA 186 P AAP RP + P GS ++ P G P+AL Sbjct: 551 PPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLV 610 Query: 187 GSDL 190 GS L Sbjct: 611 GSSL 614 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 52.8 bits (125), Expect = 2e-07 Identities = 43/136 (31%), Positives = 57/136 (41%), Gaps = 25/136 (18%) Query: 58 PAPRERPAAARLSALAAAQPRRRSPG-PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116 P P L+ AA PG P G +P PP L+ + P P AP+P P Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNG---TPEPPLLEEKPPPTPPPAPTPQP 1469 Query: 117 LPARPSSPPPRPSLPS----------GPHRPVL---PPSALAAPRP-------PLARPLP 156 P P PPP+P+LPS P P L PP A+ +P P PLA P Sbjct: 1470 QPP-PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528 Query: 157 QGSVTAREQEQRPRSR 172 + + + E + P +R Sbjct: 1529 EPAAPSPEDPELPDTR 1544 Score = 52.4 bits (124), Expect = 2e-07 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 5/117 (4%) Query: 46 DGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA 105 DG APAAA P P + S P P P PP P Sbjct: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ 1479 Query: 106 PAVPA-----APSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQ 157 PA+P+ AP+P P P PPP P++PS P P + LAAP A P P+ Sbjct: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE 1536 Score = 48.9 bits (115), Expect = 3e-06 Identities = 36/108 (33%), Positives = 44/108 (40%), Gaps = 4/108 (3%) Query: 36 PGPALVVAGLDGIRPAPAAAH--PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIA 93 P P L A +G P PP P P P+ P P + Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS 1494 Query: 94 SPLPPALQPRGAPAVPAAPSPGPLPARP-SSPPPRPSLPSGPHRPVLP 140 SP PP L P PA+P+ P P P A P ++PP P+ PS P P LP Sbjct: 1495 SPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS-PEDPELP 1541 Score = 38.5 bits (88), Expect = 0.004 Identities = 45/140 (32%), Positives = 53/140 (37%), Gaps = 25/140 (17%) Query: 4 GVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRER 63 G +AA G A GGG R + + PG G AG A PP PR Sbjct: 364 GPEAAGGGGAGGGGGGYRPI---IQSPGYKTGKGGYGAAAG--------GATRPPPPRST 412 Query: 64 --PAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPP--ALQPRG---------APAVPA 110 P L AAA ++ G GG GG SP P L P+ A + Sbjct: 413 ATPKCQSLGGPAAAYATGKASGA-GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSK 471 Query: 111 APSPGPLPARPSSPPPRPSL 130 APS P +P S PP P L Sbjct: 472 APSYSGGPPQPPSGPPPPGL 491 Score = 37.7 bits (86), Expect = 0.006 Identities = 52/173 (30%), Positives = 57/173 (32%), Gaps = 24/173 (13%) Query: 31 GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARL---SALAAAQPRRRSPGPQGG 87 GG L L A RP P PP PR P L S+ AAA + SP Sbjct: 210 GGGVLGPAGLGPAQTPPYRPGPPDP-PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF 268 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP-----------SLPSGPHR 136 G P P PR + P A+P PPP S PS HR Sbjct: 269 SGAAPGPPPPERALPRQDTVIKHYQRPA--SAQPPPPPPPAHALQHYLSCGGSYPSMGHR 326 Query: 137 PVLPPSALAA--PRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPVHAG 187 L S L P P P G A + RA PEA G AG Sbjct: 327 ANLACSPLGGGEPSPGAGEPSKAGPSGA-----TAGASGRATGPEAAGGGGAG 374 Score = 37.4 bits (85), Expect = 0.008 Identities = 41/154 (26%), Positives = 52/154 (33%), Gaps = 41/154 (26%) Query: 47 GIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQ------GGGGGDIASPLPPAL 100 G +P+ APR P + + Q RS P GG D PP Sbjct: 911 GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPP-- 968 Query: 101 QPRGAPAVPAAPSPGP---------LPAR--------------PSSPPPRPS-------- 129 + G P A P PGP P R P+ PP PS Sbjct: 969 EDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLG 1028 Query: 130 -LPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 + SGPH+ PP P PP P+G +T+ Sbjct: 1029 LIQSGPHQ-AAPPPPPPPPPPPAPASEPKGGLTS 1061 Score = 33.1 bits (74), Expect = 0.15 Identities = 40/156 (25%), Positives = 55/156 (35%), Gaps = 23/156 (14%) Query: 57 PPAPRERPAAARLSALA----AAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 PP P R A+ A A P+ +P P+ S PP P A P AP Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729 Query: 113 SPGPLPARPSSPPPRPSLPSGPHRPV-----------LPPSALAAPRPPLARPLPQGSVT 161 P RP + RP+ P +LA +P +R LP+ T Sbjct: 1730 EK-PSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSR-LPKARPT 1787 Query: 162 AREQEQRPRSRRR------AGAPEALGPVHAGSDLE 191 + E P+ R++ A GP + SD E Sbjct: 1788 KVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSE 1823 Score = 32.3 bits (72), Expect = 0.26 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 11/79 (13%) Query: 82 PGPQG----GGGGDIASPLPPALQPRGAPAVPA-APSPGPLPARPSSPPPRPSLPSGPHR 136 P P G GG D+ LPP P+ P+V + APSP P ++ P+ G + Sbjct: 776 PTPHGLLLEAGGPDLPLVLPPP-PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQ 834 Query: 137 PVLPPSALAAPRPPLARPL 155 P PP P PP PL Sbjct: 835 PPPPP-----PPPPPPMPL 848 Score = 31.6 bits (70), Expect = 0.45 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 1/85 (1%) Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQ 157 PAL P G P+PGP R P + GP RP P P A P Sbjct: 1132 PALSPLGDIDF-CPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASA 1190 Query: 158 GSVTAREQEQRPRSRRRAGAPEALG 182 + T ++ R R R R E G Sbjct: 1191 STPTDGAKKPRGRGRGRGRKAEEAG 1215 Score = 31.2 bits (69), Expect = 0.58 Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 2/96 (2%) Query: 40 LVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPA 99 L + L G P+P A P A A S A G GGGGG P Sbjct: 329 LACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPG 388 Query: 100 LQP-RGAPAVPAAPSPGPLPARPSSPPPRPSLPSGP 134 + +G A + P P R ++ P SL GP Sbjct: 389 YKTGKGGYGAAAGGATRPPPPRSTATPKCQSL-GGP 423 Score = 28.1 bits (61), Expect = 4.9 Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 24/126 (19%) Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP-------RGAPA 107 +H P+P P+A+++ + +P R PQ P PP P R Sbjct: 807 SHAPSPS--PSASKVG-VHLLEPATRDGAPQPPP----PPPPPPPPMPLQLEAHLRSHGL 859 Query: 108 VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR----------PLPQ 157 PAAPSP P PP G P+ P PP + P PQ Sbjct: 860 EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ 919 Query: 158 GSVTAR 163 G+ R Sbjct: 920 GTKAPR 925 Score = 28.1 bits (61), Expect = 4.9 Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 20/83 (24%) Query: 83 GPQGGGGGDIASPLPPAL--QPRGAPAVPAAPSP--------GPLPARPSSPPPRPSLPS 132 GP G A P P L P P +P+ + GP A P PPP P Sbjct: 991 GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPP--- 1047 Query: 133 GPHRPVLPPSALAAPRPPLARPL 155 PP+ + P+ L P+ Sbjct: 1048 -------PPAPASEPKGGLTSPI 1063 >gi|171906567 peripheral benzodiazepine receptor-associated protein 1 isoform b [Homo sapiens] Length = 1797 Score = 52.0 bits (123), Expect = 3e-07 Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 80 RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLP---ARPSSPPPRPSLPSGPHR 136 R+ P G I +P+ PAL P PA + PSP P P A +S P P PS P + Sbjct: 998 RTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQ 1057 Query: 137 PVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGA 177 P P P A P + + + E P S+ AGA Sbjct: 1058 HPAPLGTQEPPGAPPASPSREMAKGSHEDPPAPCSQEEAGA 1098 Score = 30.0 bits (66), Expect = 1.3 Identities = 33/93 (35%), Positives = 39/93 (41%), Gaps = 25/93 (26%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL- 96 PAL A L PA P+P P A + LA+A P G GD +SPL Sbjct: 1016 PALAPASL------PARVSCPSPHPSPEAR--APLASASP----------GPGDPSSPLQ 1057 Query: 97 -PPAL---QPRGAPAVPAAPSPGPLPARPSSPP 125 P L +P GAP PA+PS PP Sbjct: 1058 HPAPLGTQEPPGAP--PASPSREMAKGSHEDPP 1088 >gi|171906559 peripheral benzodiazepine receptor-associated protein 1 isoform a [Homo sapiens] Length = 1857 Score = 52.0 bits (123), Expect = 3e-07 Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 80 RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLP---ARPSSPPPRPSLPSGPHR 136 R+ P G I +P+ PAL P PA + PSP P P A +S P P PS P + Sbjct: 1058 RTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQ 1117 Query: 137 PVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGA 177 P P P A P + + + E P S+ AGA Sbjct: 1118 HPAPLGTQEPPGAPPASPSREMAKGSHEDPPAPCSQEEAGA 1158 Score = 30.0 bits (66), Expect = 1.3 Identities = 33/93 (35%), Positives = 39/93 (41%), Gaps = 25/93 (26%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL- 96 PAL A L PA P+P P A + LA+A P G GD +SPL Sbjct: 1076 PALAPASL------PARVSCPSPHPSPEAR--APLASASP----------GPGDPSSPLQ 1117 Query: 97 -PPAL---QPRGAPAVPAAPSPGPLPARPSSPP 125 P L +P GAP PA+PS PP Sbjct: 1118 HPAPLGTQEPPGAP--PASPSREMAKGSHEDPP 1148 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.137 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,800,467 Number of Sequences: 37866 Number of extensions: 1159769 Number of successful extensions: 31794 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1411 Number of HSP's successfully gapped in prelim test: 2394 Number of HSP's that attempted gapping in prelim test: 8655 Number of HSP's gapped (non-prelim): 13086 length of query: 195 length of database: 18,247,518 effective HSP length: 97 effective length of query: 98 effective length of database: 14,574,516 effective search space: 1428302568 effective search space used: 1428302568 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.