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Search of human proteins with 117938768
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938768 GNAS complex locus alex [Homo sapiens]
(626 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938768 GNAS complex locus alex [Homo sapiens] 1290 0.0
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 87 4e-17
gi|163965366 nascent polypeptide-associated complex alpha subuni... 86 1e-16
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 86 1e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 85 2e-16
gi|160707881 formin 2 [Homo sapiens] 84 4e-16
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 82 2e-15
gi|116284392 mucin 2 precursor [Homo sapiens] 80 6e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 80 6e-15
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 80 7e-15
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 80 7e-15
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 80 7e-15
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 80 7e-15
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 79 1e-14
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 77 5e-14
gi|210032580 SET domain containing 1B [Homo sapiens] 73 9e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 73 9e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 72 1e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 72 2e-12
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 72 2e-12
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 71 3e-12
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 71 3e-12
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 70 4e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 70 6e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 70 8e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 70 8e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 70 8e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 70 8e-12
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 69 2e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 69 2e-11
>gi|117938768 GNAS complex locus alex [Homo sapiens]
Length = 626
Score = 1290 bits (3337), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MMARPVDPQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSSLD 60
MMARPVDPQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSSLD
Sbjct: 1 MMARPVDPQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSSLD 60
Query: 61 SPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQ 120
SPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQ
Sbjct: 61 SPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQ 120
Query: 121 TLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGF 180
TLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGF
Sbjct: 121 TLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGF 180
Query: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGW 240
PELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGW
Sbjct: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGW 240
Query: 241 RSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK 300
RSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK
Sbjct: 241 RSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK 300
Query: 301 EPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTP 360
EPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTP
Sbjct: 301 EPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTP 360
Query: 361 GHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRP 420
GHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRP
Sbjct: 361 GHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRP 420
Query: 421 GQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLL 480
GQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLL
Sbjct: 421 GQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLL 480
Query: 481 RGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAES 540
RGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAES
Sbjct: 481 RGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAES 540
Query: 541 PSATYSATFSCKPSGAASVDLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSGPRSAQR 600
PSATYSATFSCKPSGAASVDLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSGPRSAQR
Sbjct: 541 PSATYSATFSCKPSGAASVDLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSGPRSAQR 600
Query: 601 RNAVSSSTNNSRTKRWATCVRTACCF 626
RNAVSSSTNNSRTKRWATCVRTACCF
Sbjct: 601 RNAVSSSTNNSRTKRWATCVRTACCF 626
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 87.4 bits (215), Expect = 4e-17
Identities = 161/596 (27%), Positives = 210/596 (35%), Gaps = 125/596 (20%)
Query: 8 PQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSSLDSPVGSMQ 67
P+ P T R G+ P + P ++SP ASG ++ P+G +
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPA------KNTSPGPVSSPG-RASG---TTRPGPLGQ-K 123
Query: 68 ALRPSAQHSWS-------PEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQ 120
LR SA+ + + P+ S + A DT+ P T P A RS+
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTS------GPTPGTPSPAMAR-----RSR 172
Query: 121 TLLQEAQVLQGSPELLPRSPK--PSGLQRLAPEEATALP-------------LRRLCHLS 165
E + + +P PR P P A E +T P L+R S
Sbjct: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232
Query: 166 LMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKR 225
L ++ R P A A Q +P+ A PP+ P AP A P
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP-ALGPLS 291
Query: 226 LSDLLLTSRAAAPGWRSPDPRSRLAAPP----------LGSTTLPSTWT----APQSRLT 271
S L S +A P +P L +PP LGS TL +T + P S L
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351
Query: 272 ARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPG-------QP 324
P ++P P + + P P P PL P P Q
Sbjct: 352 TPPPQAP-PALALPPLQAP-----------PSPPASPPLSPLATPSPQAPNALAVHLLQA 399
Query: 325 QRIPLPGQPLQPQPILTPGQPQKIPT---PGQHQPILTPGHSQPIPTPGQPLPPQPIPTP 381
P P P+Q P P P P+ P Q P L Q P+P P P TP
Sbjct: 400 PFSPPPSPPVQA-PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458
Query: 382 GRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLR------PGQ---------PMSP 426
P P P+ P L P Q P P PPL+ L PGQ PMSP
Sbjct: 459 P-PQAPPPLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515
Query: 427 QLRQTQGLP--LPQPLL--PPGQPKSAG--RPLQPLPPGPDARSIS----------DPPA 470
P L PLL PP P S P +P PGPD S+S PP
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT-SVSGPRLTLALAPGPPP 574
Query: 471 PRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDA 526
P SR P L G P A ++A + ++G+ + A SP PPDA
Sbjct: 575 PPSRSPSSTLSG-----PDLAGHSSSATSTPEELRGYDSGPEGGAAASP---PPDA 622
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 85.9 bits (211), Expect = 1e-16
Identities = 118/451 (26%), Positives = 158/451 (35%), Gaps = 72/451 (15%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQS 196
P +P + ++P EA+ LP L KD T H P T +A + S
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQG--SKDSPATTHSPTPPSPKGAPTPSAVTPLS 874
Query: 197 RPRVRSASLPPR-------TRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRL 249
+ +LPP+ LP + P+ PK+ L +TS + +P P+
Sbjct: 875 P---KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 250 AAP-PLGSTTLPSTWTAPQSR---LTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMP 305
A+P P G+ T P+ T P + T P +P P P P
Sbjct: 932 ASPSPKGAPTPPAA-TPPSPKGGPATPSPKWAPTPPAAT-----------------PPSP 973
Query: 306 RREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQP 365
+ P P PP P G P P P P P P + P TP +
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSP-KGGPATPSPKGAPTPPAVTPPSPKGSPAATP-FPKG 1031
Query: 366 IPTPGQPLPPQPIPTP-------GRPLTPQP-IPTP-GRPLTPQPIQMPGRPLRLPPPLR 416
TP PP P +P G P TP +P+P G P TP P P PP +
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091
Query: 417 LLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLP 476
G P +P +G P+P PP PK G P G + PP+P+
Sbjct: 1092 ----GGPATPS---PKGAPMPPAATPPS-PK--GGLATPPHKGAPTTPAATPPSPK---- 1137
Query: 477 IRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIA 536
G LA P +P AA + G A T+P PP G
Sbjct: 1138 -----GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL------ 1186
Query: 537 AAESPSATYSATFSCKPSGAASVDLRVPSPK 567
A SP + + PS L PSPK
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGG--LATPSPK 1215
Score = 75.5 bits (184), Expect = 1e-13
Identities = 112/434 (25%), Positives = 151/434 (34%), Gaps = 37/434 (8%)
Query: 174 TAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTS 233
T P+G P + + + P + A P PS + PK T+
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP----TT 1197
Query: 234 RAAAPGWRSPDPRSRLAAP-PLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQL 292
AA P P P+ LA P P G+ T P+ A PS P + P+
Sbjct: 1198 PAATP----PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253
Query: 293 RRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPG 352
K P L+G PP + P P P+ P+ PTP
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP 1313
Query: 353 QHQPILTPGHSQPIPTPGQPLPPQPIP--TPGRPLTPQPIP-TPGRPLTPQPIQMPGRPL 409
P G P G P PP P G P P P + G P TP + P P
Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 410 RLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQP--LPPGPDARSISD 467
P G P +G +P P P P A PL P P P R +
Sbjct: 1374 ATPS-----HKGGPAMTPPSPKRGPAIPSPKGDPTSP--AVIPLSPKKAPATPVTREGAA 1426
Query: 468 PPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDAS 527
P+ P + L + P ++P+ A + KG P PA T P+ P A
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT--PSSKGDPT---LPAVTPPSPKEPPAP 1481
Query: 528 AGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVP-SPKP-RALSRSRRYPWRRSADR 585
++A + SP A + P GA ++ +P SPK A SRR P +A
Sbjct: 1482 K-----QVATSSSPK---KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
Query: 586 CAKK-PWRSGPRSA 598
+KK P P+ A
Sbjct: 1534 LSKKTPATLAPKEA 1547
Score = 58.2 bits (139), Expect = 2e-08
Identities = 98/416 (23%), Positives = 132/416 (31%), Gaps = 53/416 (12%)
Query: 132 SPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAA 191
SP+ P +P P G AP P GT P P T +
Sbjct: 1319 SPKGSPGTPPPKG----APTPPAVTP----------PSPKGTPTLPATTPSSKGGPTTPS 1364
Query: 192 SSRQSRPRVRSASLP--PRTRLPSGSQAPSAAHPK---RLSDLLLTSRAAAPGWRSPDPR 246
S P + S P PS + P+ PK ++ S AP +P R
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA--TPVTR 1422
Query: 247 SRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPR 306
A P G T P+ + A + P S + DP L P +
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT-PSSKGDPTL---------PAVTP 1472
Query: 307 REEKYPLRGTDPLPPGQPQRIPLPGQPLQPQ--PILTPGQPQKIP-TPGQHQPILTPGH- 362
K P P++ P P+ P + P P+++P TP + + P
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 363 --SQPIPT---PGQPLPPQPIPTPGRPLTPQPIPTPGR-PLTPQ-------PIQMPGRPL 409
S+ P P + L P + P TP IPTP P TP P P
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPA-IPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 410 RLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPL-QPLPPGPDARSISDP 468
P P LL P SP ++ P P + PP K P + P P S
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEA---PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648
Query: 469 PAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPP 524
+P S + G P A + PA TP T+PT P
Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704
Score = 47.8 bits (112), Expect = 3e-05
Identities = 100/457 (21%), Positives = 144/457 (31%), Gaps = 83/457 (18%)
Query: 132 SPELLPRSPKPSGLQRL------APEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSH 185
SP+ P +P P G L +P+E A P R + TA LS
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR-------RDPIAPTA-----TLLSK 1536
Query: 186 KSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDP 245
K+ A + ++ A +PP +PS + P+ PK + A++P + P
Sbjct: 1537 KTPATLAPKE-------ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP--AVTP 1587
Query: 246 RSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMP 305
+ AP +P T+P P +P P + P
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPS------PKEAPTPPA--------------------VTP 1621
Query: 306 RREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQP 365
EK P P P G P P+ L+ P K+ P P
Sbjct: 1622 PSPEKGP---ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 366 IPTPGQPLPPQP-------IPTPGRPLTPQPIPTPGRPLTPQPIQMPGR--PLRLPPPLR 416
+ P P PT P T + T P+ P P G PL P
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT-SPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 417 LLRPGQPMSPQLRQTQGLPLPQ-PLLPPGQPKSA---GRPLQPLPPGPDARSISDPPAPR 472
LL + S + P+ PL PP S + + P P++ S+S P+P
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797
Query: 473 SRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSI 532
LP L + LP ++ P A E P + P S G
Sbjct: 1798 VSLP--LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 533 GEIAA-----------AESPSATYSATFSCKPSGAAS 558
+ +PSA T + K SG S
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTES 1892
Score = 41.2 bits (95), Expect = 0.003
Identities = 98/429 (22%), Positives = 145/429 (33%), Gaps = 78/429 (18%)
Query: 2 MARPVDPQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNS------PAWEASGLH 55
M P P P S + +P+ TA LL K+ P+ L PA
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559
Query: 56 WSSLDSPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTS-LPREAAVN 114
+ P PS++ + SP P+V P ++ ++ L P ++TS P+EA
Sbjct: 1560 KTPA-IPTPKEAPATPSSKEASSP-PAVTPS-TYKGAPSPKELLIPPAVTSPSPKEAPT- 1615
Query: 115 FSYRSQTLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTT 174
V SPE P +P P G P ++L S+ K +G T
Sbjct: 1616 ----------PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK-MGAT 1664
Query: 175 AHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSR 234
P+ S K A + V A P T P P R S
Sbjct: 1665 V-----PQAS-KGLPAKKGPTALKEVLVAPAPEST--------PIITAPTRKGPQTKKSS 1710
Query: 235 AAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRR 294
A +P PDP ++ + ST P AP + S++ + + + P L
Sbjct: 1711 ATSPPI-CPDPSAKNGSKGPLSTVAP----APLLPVQKDSSKTAKGKDASHSPKGP-LAP 1764
Query: 295 KQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQH 354
+ + PL EK LP + + P P+ P P +PT
Sbjct: 1765 PESKASTPLTAAAFEKV-------LPKPESASVSAAPSP----PVSLPLAPSPVPTLPPK 1813
Query: 355 QPILTPGHSQPIPTPGQPL------------PPQPI-------------PTPGRPLTPQP 389
Q L + +P +PL PP+PI PTP P P
Sbjct: 1814 QQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP 1873
Query: 390 IPTPGRPLT 398
P+ +P+T
Sbjct: 1874 TPSAKQPVT 1882
Score = 34.7 bits (78), Expect = 0.27
Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 16/165 (9%)
Query: 363 SQPIPTPG--QPLPPQPI---PTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRL 417
S P+P P + LP + PT + L P G P +P + + + P L L
Sbjct: 506 SPPLPDPEDLKNLPSSVLVKFPTQ-KDLQTVPASLEGAPFSPAQAGLTTK--KDPTVLPL 562
Query: 418 LRPGQPMSPQLRQTQGLPLPQPLLPPGQ--PKSAGRPLQPLPPGPDARSISDPPAPRSRL 475
++ SP + T P PL P KS G +PLP G A S++ P S
Sbjct: 563 VQAAPKNSPSFQSTSSSP-EIPLSPEATLAKKSLG---EPLPIGKPASSMTSPLGVNSSA 618
Query: 476 PIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPT 520
+ P A P ++ T+ +P + PA +PT
Sbjct: 619 SVIKTDSYAG--PDSAGPLLKSSLITPTVAAFPLESADPAGVAPT 661
Score = 32.0 bits (71), Expect = 1.8
Identities = 52/176 (29%), Positives = 67/176 (38%), Gaps = 31/176 (17%)
Query: 423 PMSPQLRQTQGLPLPQPLLPP-------GQPKSAGRPLQPLP-PGPDARSISDPPAPRSR 474
PMS L T L P P LPP P SA P P P A + + P P+S
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
Query: 475 LPIRLLRGLLARLP--------GGASPRAAAAAA---CTTMKGWPAATMTPAETSPTMGP 523
L G P SP A A A+ T+KG P+++ A +
Sbjct: 87 SGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHS 146
Query: 524 PDASAGF------SIGEIAAAESPSA-TYSATFSCKPSGAASVDLRVPS---PKPR 569
S+ F S +A AES S T SA + PS + +VPS P P+
Sbjct: 147 VQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA--PSEPKTNLNKVPSEVVPNPK 200
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 85.5 bits (210), Expect = 1e-16
Identities = 129/439 (29%), Positives = 158/439 (35%), Gaps = 95/439 (21%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQS 196
P PKP GLQ L P + T P R KD P L+ S +AA Q+
Sbjct: 269 PSQPKPKGLQALRPPQVT--PPR---------KDAAPALGPLSSSPLATPSPSAALQSQA 317
Query: 197 RPRV----RSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAP 252
P + S+SL + P PS + P L L S A P + A
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL--PSPPATPPSQ--------ATT 367
Query: 253 PLGSTTLPSTWT----APQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRRE 308
LGS TL +T + P S L P ++P P + + P P P
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPPLQAP-----------PSPPASP 415
Query: 309 EKYPLRGTDPLPPG-------QPQRIPLPGQPLQPQPILTPGQPQKIPT---PGQHQPIL 358
PL P P Q P P P+Q P P P P+ P Q P L
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQAPPSL 474
Query: 359 TPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLL 418
Q P+P P P TP P P P+ P L P Q P P PPL+ L
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPP-PQAPPPLAAPPLQLAKPPPQAP--PALATPPLQAL 531
Query: 419 R------PGQ---------PMSPQLRQTQGLP--LPQPLL--PPGQPKSAG--RPLQPLP 457
PGQ PMSP P L PLL PP P S P +P
Sbjct: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591
Query: 458 PGPDARSIS----------DPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGW 507
PGPD S+S PP P SR P L G P A ++A + ++G+
Sbjct: 592 PGPDT-SVSGPRLTLALAPGPPPPPSRSPSSTLSG-----PDLAGHSSSATSTPEELRGY 645
Query: 508 PAATMTPAETSPTMGPPDA 526
+ A SP PPDA
Sbjct: 646 DSGPEGGAAASP---PPDA 661
Score = 79.7 bits (195), Expect = 7e-15
Identities = 164/657 (24%), Positives = 225/657 (34%), Gaps = 97/657 (14%)
Query: 8 PQRSPDPTFRSSTRHSGKLEPMEAT---AHLLRKQCPSRLNSPAWEASGLHWSSLDSPVG 64
P+ P + +S+R+ P A + P ++SP ASG ++ P+G
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG-RASG---TTRPGPLG 130
Query: 65 SMQALRPSAQHSWS-------PEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSY 117
+ LR SA+ + + P+ S + A DT+ P T P A
Sbjct: 131 Q-KGLRISAEETVARGKATEAPKRSALSAGARRDTS------GPTPGTPSPAMAR----- 178
Query: 118 RSQTLLQEAQVLQGSPELLPRSPK--PSGLQRLAPEEATALP-------------LRRLC 162
RS+ E + + +P PR P P A E +T P L+R
Sbjct: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 163 HLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAH 222
SL ++ R P A A Q +P+ A PP+ P AP A
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP-ALG 297
Query: 223 PKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQI 282
P S L S +AA +S P + A P S++L P PS P Q
Sbjct: 298 PLSSSPLATPSPSAA--LQSQAPPTLPATP--HSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 283 RESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPL---PPGQPQRIPLPGQPLQPQPI 339
S P + P + P PL PP P + LP PLQ P
Sbjct: 354 LPSPPATPP-SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP--PLQAPP- 409
Query: 340 LTPGQPQKIP--TPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPL 397
P P P TP P H + P P P P+ P P P+ P
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHL--LQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 398 TPQPIQMPGRPLRLPPPLRLLRPGQPMS---PQLRQTQGLPLPQPLLPPGQ--PKSAGRP 452
+ P + PL++PP P P + PQ P Q PP Q P A P
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527
Query: 453 LQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATM 512
LQ LP P + P +P + LP+ LA P A P AA + T+
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPM----SPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583
Query: 513 TPAETSPTMGPPDASAGFSIGEIAA-------AESPSATYSAT----------------- 548
PT GP + +G + A + SPS+T S
Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
Query: 549 -FSCKPSGAASV----DLRVPSPKPRALSRSRRYPWRRSADRCAKKPW--RSGPRSA 598
+ P G A+ D + + P A SR P A PW +GP SA
Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700
Score = 44.3 bits (103), Expect = 3e-04
Identities = 81/353 (22%), Positives = 118/353 (33%), Gaps = 41/353 (11%)
Query: 232 TSRAAAPGWRSPDPRSRLAAPP----LGSTTLPSTWTAPQSRLTARP-----SRSPEPQI 282
T A APG +P P PP L + + L R + PE
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 283 RESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRI-------PLPGQPLQ 335
R R + + P R E P + T P P P R PL + L+
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
Query: 336 PQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGR 395
T + + P + PTPG P P + T +P P
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPAP 194
Query: 396 PLTPQ-PIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPL- 453
P+ P + P + + P + + R + G L +P S+ PL
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSP--AARRRPSAGGGLQRP--ASRSLSSSATPLS 250
Query: 454 QPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMT 513
P GP AR PA S+ + L+ L R P PR AA A + P AT +
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 514 PAETSPTMGPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPSP 566
P+ + PP P+ +S++ +C+ A + L PSP
Sbjct: 309 PSAALQSQAPPTL--------------PATPHSSSLTCQL--ATPLPLAPPSP 345
Score = 30.8 bits (68), Expect = 3.9
Identities = 51/227 (22%), Positives = 80/227 (35%), Gaps = 34/227 (14%)
Query: 385 LTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPG-----QPMSPQLRQTQGLPLPQP 439
LTP+P PG P P P+ P LR+L +P++ + G +P+
Sbjct: 25 LTPRP---PGSPRPPPPVT--------PAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 440 LLPPGQPKSAGRPLQPLPPGPDA--RSISDPPAPRSRLPIRLLRGLLARLPGG-ASPRAA 496
G +SAG + P A R PPA + PG +SP A
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS-------------PGPVSSPGRA 120
Query: 497 AAAACTTMKGWPAATMTPAETSPTMGPPDAS--AGFSIGEIAAAESPSATYSATFSCKPS 554
+ G ++ ET +A + S G P+ + + S
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 555 GAASVDLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSGPRSAQRR 601
AA ++ +P P P A R R+S ++ +A+RR
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 85.1 bits (209), Expect = 2e-16
Identities = 146/524 (27%), Positives = 193/524 (36%), Gaps = 99/524 (18%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSL---------MEKDLGTTAHPRGFPE----- 182
P PKP GLQ L P + T P R+ +L GT A P P+
Sbjct: 269 PSQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326
Query: 183 ----------------LSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHP--K 224
L+ S +A S Q+ P + PP PS + P A P +
Sbjct: 327 LPATLPPSPPLATPLPLAPPSPSAPPSLQTLP--SPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 225 RLSDLLLTSRAAAPGWRSPDP----RSRLAAPPLGSTTLPST--------------WTAP 266
+ + + +P ++P S A LGS TL +T T+P
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 267 QSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQR 326
SR + P SP Q S P L+ PL +PL+ L PQ
Sbjct: 445 -SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL-TIHPLQALSSLASHSPQ- 501
Query: 327 IPLPG---QPLQPQPILTPGQPQKIPT-----PGQHQPILTP----GHSQPIPTPGQPLP 374
PL PL+ Q L P Q P P ++ P L P S P+ TP P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 375 PQPIP----TPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQL-- 428
P P P P PLT P TP TP P Q P P PPL+ L P P+SP
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPP-QAP--PALASPPLQGL-PSPPLSPLATP 617
Query: 429 --RQTQGLPLPQPLLPPGQPKSAGRPLQPL----PPGPDARSI-------SDPPAPRSRL 475
+ L LP PP P A PL PL P P+A ++ S PP+P +
Sbjct: 618 PPQAPPXLALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675
Query: 476 PIRLLRG---LLARLPGGASPRAAAAAACTTMKGWPAA-TMTPAETSPTMGPPDASAGFS 531
P + P +P + AA PA+ M+P+ T P PP +A
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
Query: 532 IGEIAAAESPSATYSATFSCK-PSGAASVDLRVPSPKPRALSRS 574
+ SP + SAT + P A+ L+VP P +L S
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS 779
Score = 80.9 bits (198), Expect = 3e-15
Identities = 154/600 (25%), Positives = 203/600 (33%), Gaps = 112/600 (18%)
Query: 11 SPDPTFRSSTRHSGKLEPMEATAHLLRK---QCPSRLNSPAWEA--SGLHWSSLDSPVGS 65
SP T S S PM+A L Q P L SP+ +A S L SSL + S
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT-S 417
Query: 66 MQALRPSAQHSW---------------SPEPSVVPDQAWEDTALHQKKLCPLSLTSLPRE 110
+ + A HS+ S S PD L PL + P
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 111 AAVNFSYRSQTLLQEAQVLQGSPELLPRSPKPSGLQR-LAPEEATALPLRRLCHLSLMEK 169
+ ++ S + Q L P++P S + L + + A P + SL
Sbjct: 478 SPLS----SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL--- 530
Query: 170 DLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDL 229
TT P L+ AS+ + P + + P L + + P+ S +
Sbjct: 531 ---TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 230 LLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLT---ARPSRSPEPQIRESE 286
A P SP P L +PPL P P L A PS P +
Sbjct: 588 ATPPPQAPPALASP-PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646
Query: 287 QRDPQ------LRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPIL 340
PQ + Q + P P + + PP P P P Q P L
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-------PPASPPVSPSATPPSQAPPSL 699
Query: 341 TPGQPQKIPTPGQHQPI---LTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRP- 396
Q P+P P+ TP P P PL P P P++P P P P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Query: 397 -LTPQPIQMP-GRPLRLP-----------------PPLRLLR------PGQ--------- 422
L P+Q+P P LP PPL+ L PGQ
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819
Query: 423 PMSPQLRQTQGLP--LPQPLL--PPGQPKSAG--RPLQPLPPGPDARSIS---------- 466
PMSP P L PLL PP P S P +P PGPD S+S
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT-SVSGPRLTLALAP 878
Query: 467 DPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDA 526
PP P SR P L G P A ++A + ++G+ + A SP PPDA
Sbjct: 879 GPPPPPSRSPSSTLSG-----PDLAGHSSSATSTPEELRGYDSGPEGGAAASP---PPDA 930
Score = 75.1 bits (183), Expect = 2e-13
Identities = 153/582 (26%), Positives = 191/582 (32%), Gaps = 94/582 (16%)
Query: 61 SPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALH---QKKLCPLSLTSLPREAAVNFSY 117
SP G+ P ++ +P P+ +P T L P SL +LP A S
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
Query: 118 RSQTL----LQEAQVLQGSPEL----------LPRSPKPSGLQRLAPEEATALPLRRLCH 163
++ +Q LQ P + L P P L L + P + H
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 164 LSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLP-------SGSQ 216
L T A L+ S A++ S P SLP L S
Sbjct: 428 SFLTMSPRQTQA------SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481
Query: 217 APSAAHP-KRLSDLLLTSRAAAPGWRSPDPRSRLAAPPL---GSTTLPSTWTAPQSRLTA 272
+P HP + LS L S A P S L PPL S PS T P S T
Sbjct: 482 SPLTIHPLQALSSLASHSPQA--------PLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 273 R----PSRSPEP-QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRI 327
PS +P P Q + P L PL + P T P PP P I
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL-----QAPPSPLTTP-PPETPSSI 587
Query: 328 PLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTP 387
P P Q P L Q +P+P P+ TP P PL P P PL+P
Sbjct: 588 ATP--PPQAPPALASPPLQGLPSPPL-SPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Query: 388 QPIPTPGRP-----------LTPQP---IQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQ- 432
P+P P +P P +Q P P PP P P L
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704
Query: 433 GLPLPQPLLPPGQPKSAGRPLQP---------LPPGPDARSISDPPAPRSRLPIRLLRGL 483
+P P PP P + P P +PP P A PP S P + L
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA----SPPMSPSATPPPRVPPL 760
Query: 484 LARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSA 543
LA P P A+ + + P T P P A F G+ A SPSA
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-GQ--APFSPSA 817
Query: 544 TYSATFSCKPSGAASVDLRVP----SPKPRA---LSRSRRYP 578
+ + P A L P P P A L RR P
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Score = 68.9 bits (167), Expect = 1e-11
Identities = 159/627 (25%), Positives = 217/627 (34%), Gaps = 96/627 (15%)
Query: 8 PQRSPDPTFRSSTRHSGKLEPMEAT---AHLLRKQCPSRLNSPAWEASGLHWSSLDSPVG 64
P+ P + +S+R+ P A + P ++SP ASG ++ P+G
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG-RASG---TTRPGPLG 130
Query: 65 SMQALRPSAQHSWS-------PEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSY 117
+ LR SA+ + + P+ S + A DT+ P T P A
Sbjct: 131 Q-KGLRISAEETVARGKATEAPKRSALSAGARRDTS------GPTPGTPSPAMAR----- 178
Query: 118 RSQTLLQEAQVLQGSPELLPRSPK--PSGLQRLAPEEATALP-------------LRRLC 162
RS+ E + + +P PR P P A E +T P L+R
Sbjct: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 163 HLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAH 222
SL ++ R P A A Q +P+ A PP+ P AP A
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP-ALG 297
Query: 223 PKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTA-PQSRLTARPSRSPEPQ 281
P S L S + P P + AA PL +T PS A P PS P Q
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDN--AATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 282 IRESEQRDPQLRRKQQRWKEPLM--PRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPI 339
S P + P+ P + P++ L Q P P Q
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 340 LTPGQPQKIPT-------PGQHQPILTPGHSQPIPTPGQPLPPQ-PIPTPGRP-----LT 386
+ G P T P Q Q LT S+P TP P Q P+ P P L+
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLT-SPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 387 PQPIPTPGRPLTPQPIQ--------MPGRPLR--LPPPLR----LLRPGQPMSPQLRQTQ 432
P P PLT P+Q P PL + PPL L P P T
Sbjct: 475 PAVSPL-SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 433 GLP-LPQPLLPPGQPKSA--GRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPG 489
L LP PP Q SA P PP P + PP+P + P +
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT---- 589
Query: 490 GASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSATF 549
P+A A A ++G P+ ++P T P PP ++ + A SP A+ +
Sbjct: 590 -PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP----XLALPPLQAPPSPPASPPLSP 644
Query: 550 SCKPSGAASVDLRV--------PSPKP 568
PS A L V P P P
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSP 671
Score = 47.8 bits (112), Expect = 3e-05
Identities = 86/361 (23%), Positives = 118/361 (32%), Gaps = 42/361 (11%)
Query: 232 TSRAAAPGWRSPDPRSRLAAPP----LGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQ 287
T A APG +P P PP L + + L R I ES
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 288 RDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQK 347
R R + P + P G+ +R P P + P P+ +PG+
Sbjct: 76 RAGPTRSAGTSSRNP------------ASRPPASGRGERAP-PAKNTSPGPVSSPGRASG 122
Query: 348 IPTPGQ-HQPILTPGHSQPIPTPGQPLPPQ--PIPTPGRPLTPQPIPTPGRPLTPQPIQM 404
PG Q L + + P+ + R T P P P + +
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 405 PGRPLRLPPPLRLLRPGQP-------MSPQLRQTQGLPLP----QPLLPPGQPKSAGRPL 453
G + LP P RP P +S + P P +P G + A R L
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 454 Q--------PLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMK 505
P GP AR PA S+ + L+ L R P PR AA A +
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAPALGPLS 300
Query: 506 GWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPS 565
P AT +P+ T PP +A + P AT PS S+ +PS
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ-TLPS 359
Query: 566 P 566
P
Sbjct: 360 P 360
Score = 30.8 bits (68), Expect = 3.9
Identities = 51/227 (22%), Positives = 80/227 (35%), Gaps = 34/227 (14%)
Query: 385 LTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPG-----QPMSPQLRQTQGLPLPQP 439
LTP+P PG P P P+ P LR+L +P++ + G +P+
Sbjct: 25 LTPRP---PGSPRPPPPVT--------PAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 440 LLPPGQPKSAGRPLQPLPPGPDA--RSISDPPAPRSRLPIRLLRGLLARLPGG-ASPRAA 496
G +SAG + P A R PPA + PG +SP A
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS-------------PGPVSSPGRA 120
Query: 497 AAAACTTMKGWPAATMTPAETSPTMGPPDAS--AGFSIGEIAAAESPSATYSATFSCKPS 554
+ G ++ ET +A + S G P+ + + S
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 555 GAASVDLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSGPRSAQRR 601
AA ++ +P P P A R R+S ++ +A+RR
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 84.0 bits (206), Expect = 4e-16
Identities = 101/354 (28%), Positives = 133/354 (37%), Gaps = 69/354 (19%)
Query: 182 ELSHKSTAAASSRQSRPRVRSA--SLPPRTRLPSGSQAPSAAHP----KRLSD--LLLTS 233
E+ H A S Q+ P +LPP LP P A K S+ L+++
Sbjct: 732 EVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSP 791
Query: 234 RAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLR 293
R + S P ++ PP + L W+A Q + ++P S + + S +
Sbjct: 792 RRISVQLDSHQPTQSISQPPPPPSLL---WSAGQGQPGSQPPHSISTEFQTSHEHSVSSA 848
Query: 294 RKQQRW--KEPLMPRREEKY--------------------------------PLRGTDPL 319
K P +P E PL+GT+ L
Sbjct: 849 FKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEML 908
Query: 320 PP--------GQPQRIPLPGQPLQPQPILT-PGQPQKIPTPGQHQPILTP----GHSQPI 366
PP G P PLPG + P P L G P P PG P P G P
Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
Query: 367 PTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSP 426
P PG +PP P P PG + P P P PG + P P +PG + PPPL G P P
Sbjct: 969 PLPGAGIPPPP-PLPGAGIPPPP-PLPGAGIPPPP-PLPGAGIPPPPPLP--GAGIPPPP 1023
Query: 427 QLRQTQGLPLPQPL----LPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLP 476
L G+P P PL +PP P G + P PP P A PP P + +P
Sbjct: 1024 PL-PGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1075
Score = 79.3 bits (194), Expect = 1e-14
Identities = 94/309 (30%), Positives = 109/309 (35%), Gaps = 47/309 (15%)
Query: 198 PRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGST 257
P + A +PP LP + P P + + L G P P PP
Sbjct: 935 PPLPGAGIPPPPPLPGAAIPPPPPLPG--AGIPLPPPLPGAGIPPPPPLPGAGIPP--PP 990
Query: 258 TLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTD 317
LP P L P P P L PL P G
Sbjct: 991 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--------PGAGIP 1042
Query: 318 PLPP----GQPQRIPLPGQPLQPQPILT-PGQPQKIPTPGQHQPILTP----GHSQPIPT 368
P PP G P PLPG + P P L G P P PG P P G P P
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
Query: 369 PGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQL 428
PG +PP P P PG + P P P PG + P P +PG + PPPL R G P P L
Sbjct: 1103 PGVGIPPPP-PLPGAGIPPPP-PLPGAGIPPPP-PLPGAGIPPPPPLP--RVGIPPPPPL 1157
Query: 429 RQT----------QGLPLPQPL----LPPGQP-KSAGRPLQP------LPPGPDARSISD 467
G+P P PL +PP P G P P +PP P +
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
Query: 468 PPAPRSRLP 476
PPAP LP
Sbjct: 1218 PPAPAPPLP 1226
Score = 72.4 bits (176), Expect = 1e-12
Identities = 96/307 (31%), Positives = 109/307 (35%), Gaps = 51/307 (16%)
Query: 198 PRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGST 257
P + A +PP LP P P L + PG P P PPL
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPP------PPLPGA 1050
Query: 258 TLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTD 317
+P P L P P P L PL P G
Sbjct: 1051 GIP-----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--------PGAGIP 1097
Query: 318 PLPP----GQPQRIPLPGQPLQPQPILT-PGQPQKIPTPGQHQPILTP----GHSQPIPT 368
P PP G P PLPG + P P L G P P PG P P G P P
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 369 PGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQL 428
PG +PP P P PG + P P P PG + P P +PG + +PPP L G P P L
Sbjct: 1158 PGAGIPPPP-PLPGAGIPPPP-PLPGVGIPPPP-PLPG--VGIPPPPPLPGAGIPPPPPL 1212
Query: 429 RQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPP----APRSRLPIRLLRGLL 484
P P P LP P G P PL P +S PP S LP + G L
Sbjct: 1213 PGMGIPPAPAPPLP---PPGTGIPPPPLLP------VSGPPLLPQVGSSTLPTPQVCGFL 1263
Query: 485 -ARLPGG 490
LP G
Sbjct: 1264 PPPLPSG 1270
Score = 65.5 bits (158), Expect = 1e-10
Identities = 82/277 (29%), Positives = 96/277 (34%), Gaps = 48/277 (17%)
Query: 198 PRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGST 257
P + A +PP LP P P L + PG P P PPL
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPP------PPLPGA 1094
Query: 258 TLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTD 317
+P P L P P P L PL P G
Sbjct: 1095 GIP-----PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--------PGAGIP 1141
Query: 318 PLPP----GQPQRIPLPGQPLQPQPILT-PGQPQKIPTPGQHQPILTPGHSQPIPTPGQP 372
P PP G P PLPG + P P L G P P PG P P P PG
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP-------PPPPLPGVG 1194
Query: 373 LPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQ-MPGRPLRLPPPLRLLRPGQPMSPQLR-- 429
+PP P P PG + P P P PG + P P +P +PPP L G P+ PQ+
Sbjct: 1195 IPPPP-PLPGAGIPPPP-PLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSS 1252
Query: 430 -----QTQGL---PLPQPLLPPGQPKSAGRPLQPLPP 458
Q G PLP L G + G QP+ P
Sbjct: 1253 TLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEP 1289
Score = 36.6 bits (83), Expect = 0.071
Identities = 57/249 (22%), Positives = 82/249 (32%), Gaps = 21/249 (8%)
Query: 300 KEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQ-----PQKIPTPGQH 354
+EP P P+ LP QP P P P PG+ P +
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347
Query: 355 QPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPP 414
+ P +PG+ P+ + L +P P P +PG P P
Sbjct: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSP---APS 404
Query: 415 LRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQ-----PKSAGRPLQPLPPGP-DARSISDP 468
R +P ++P +T L P P Q P+ RP L G A +
Sbjct: 405 QRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAA 464
Query: 469 PAPRSRLPIRLLRGLLARLP-----GGASPRAAAAAACTT--MKGWPAATMTPAETSPTM 521
PA + R L GL G +PR +A + ++PA +
Sbjct: 465 PAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKAS 524
Query: 522 GPPDASAGF 530
G P A+ GF
Sbjct: 525 GAPAAADGF 533
Score = 32.0 bits (71), Expect = 1.8
Identities = 68/328 (20%), Positives = 104/328 (31%), Gaps = 57/328 (17%)
Query: 281 QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLP-------------------- 320
++++ +Q+ QL+ +QQ+ ++ L E P P P
Sbjct: 204 RLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA 263
Query: 321 PGQPQ-RIPLPGQPLQPQPILT-PGQPQKIPTPG----QHQPILTPGHSQPIPTPGQPLP 374
PG P L P+ + P +PQ+ P+PG P L +P
Sbjct: 264 PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAF 323
Query: 375 PQPIPTPGRPLTPQPI--------------------PTPGRPLTPQPIQMPGRPLRLPPP 414
P P PG P+ +PG P+ + + L P
Sbjct: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPE 383
Query: 415 LRLLRPGQPMSPQL----RQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPA 470
P P + L +Q P PL+ P K+ R L P ++S + P
Sbjct: 384 EEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSS-PNHSPSQSPNQSPR 442
Query: 471 PRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMG--PPDASA 528
+ R L RG L A+P A G A A+ + +G P
Sbjct: 443 IKRRPEPSLSRGSRTALASVAAPAKKHRAD----GGLAAGLSRSADWTEELGARTPRVGG 498
Query: 529 GFSIGEIAAAESPSATYSATFSCKPSGA 556
+ E A S + K SGA
Sbjct: 499 SAHLLERGVASDSGGGVSPALAAKASGA 526
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 81.6 bits (200), Expect = 2e-15
Identities = 90/314 (28%), Positives = 119/314 (37%), Gaps = 56/314 (17%)
Query: 193 SRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAP 252
S++ P V S P R P G P P P R P ++ P
Sbjct: 24 SQEESPSVISGK--PEGRRPQGGNQPQRTPPP----------PGKPEGRPPQGGNQSQGP 71
Query: 253 PLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYP 312
P P P + S+ P P+ + E + PQ + Q P P + E P
Sbjct: 72 P----PRPGKPEGPPPQ-GGNQSQGPPPRPGKPEGQPPQGGNQSQG--PPPRPGKPEGPP 124
Query: 313 LRGTD-----PLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIP 367
+G + P PG+P+ P G P PG+P+ P G +Q P P
Sbjct: 125 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS------QGPPP 178
Query: 368 TPGQPL--PPQ-------PIPTPGRPLTPQPI---------PTPGRPLTPQPIQMPGRPL 409
PG+P PPQ P P PG+P P P P PG+P P P Q +P
Sbjct: 179 HPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP-PSQGGNKPQ 237
Query: 410 RLPPPLRLLRPGQPMSPQLRQ-TQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDP 468
PP PG+P P ++ + P P P G P G P QPLPP P + P
Sbjct: 238 GPPP-----HPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPP-PAGKPQGPP 291
Query: 469 PAPRSRLPIRLLRG 482
P P+ P R +G
Sbjct: 292 PPPQGGRPHRPPQG 305
Score = 70.9 bits (172), Expect = 3e-12
Identities = 63/192 (32%), Positives = 81/192 (42%), Gaps = 22/192 (11%)
Query: 275 SRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTD-----PLPPGQPQRIPL 329
S+ P P+ + E PQ + Q P P + E P +G + P PG+P+ P
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQG--PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPP 188
Query: 330 PGQPLQPQPILTPGQPQKIPTPGQHQ---PILTPGHSQPIPTPGQPLPPQPIPTPGRPLT 386
G P PG+P+ P G +Q P PG + P+ G P P P PG+P
Sbjct: 189 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQG 248
Query: 387 PQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQP 446
P P +P P P PGRP PPP P QP+ P + QG P PP Q
Sbjct: 249 PPP-QEGNKPQRPPP---PGRPQGPPPPGG--NPQQPLPPPAGKPQGPP------PPPQG 296
Query: 447 KSAGRPLQPLPP 458
RP Q PP
Sbjct: 297 GRPHRPPQGQPP 308
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 80.1 bits (196), Expect = 6e-15
Identities = 88/371 (23%), Positives = 116/371 (31%), Gaps = 30/371 (8%)
Query: 196 SRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLG 255
S P + +LPP T + + P +T+ P +P +PP+
Sbjct: 1407 SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTP-------SPPIS 1459
Query: 256 STTLPSTWTAPQSRLT--ARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPL 313
+TT P T P T + P+ +P P + P P P P
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT--------PSPPTTTPITPP 1511
Query: 314 RGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPL 373
T LPP P P P TP P P P + P P P
Sbjct: 1512 ASTTTLPPTTTPSPPTT-TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 374 PPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRL---PPPLRLLRPGQ--PMSPQL 428
P P TP P T P P TP P P P PPP P P++P
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1630
Query: 429 RQTQGLPLPQPLLPPGQPKSAGRPLQPLPPG------PDARSISDPPAPRSRLPIRLLRG 482
T P P PP + P PP P + + PP PI
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690
Query: 483 LLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPS 542
SP ++ TT P++T TP+ TM P + S P
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTT-TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749
Query: 543 ATYSATFSCKP 553
T S+ + P
Sbjct: 1750 TTTSSPLTTTP 1760
Score = 69.7 bits (169), Expect = 8e-12
Identities = 77/321 (23%), Positives = 98/321 (30%), Gaps = 31/321 (9%)
Query: 173 TTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLT 232
TT P +T + + P + + PP T PS P + L T
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520
Query: 233 SRAAAPGWRSPDPRSRLAAPPLGSTTLPSTW--TAPQSRLTARPSRSPEPQIRESEQRDP 290
+ + P + P PP + + P+T T P S T P+ +P P + P
Sbjct: 1521 TTPSPPTTTTTTP------PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Query: 291 QLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPT 350
P P P T P PP P P TP P P
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP--------PPTTTPSPPTTTPI 1626
Query: 351 PGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLR 410
P + P P P P P TP P T P P TP P P P+
Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPIT 1686
Query: 411 L---PPPLRLLRPG---QPMSPQLRQTQGLPLPQPLLPP---GQPKSAGRPLQP------ 455
PP + P P SP T P PP P P P
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746
Query: 456 LPPGPDARSISDPPAPRSRLP 476
LPP + ++ P P S P
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITP 1767
Score = 57.0 bits (136), Expect = 5e-08
Identities = 61/251 (24%), Positives = 74/251 (29%), Gaps = 22/251 (8%)
Query: 339 ILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPL----TPQPIPTPG 394
I TP P P+P P + P P P P TP P+ TP P TP
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 395 RPL----TPQPIQMPGRPLRLPPPLRLLRPGQP----MSPQLRQTQGLPLPQPLLPPGQP 446
P+ TP P P P P P P P +P T P P+ PP
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSP-PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 447 KSAGRPLQPLPP-----GPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAAC 501
+ P PP P + PP P L P
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Query: 502 TTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYS---ATFSCKPSGAAS 558
TT P T T T PP + P+ T S T P+ +
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634
Query: 559 V-DLRVPSPKP 568
+ PSP P
Sbjct: 1635 LPPTTTPSPPP 1645
Score = 53.9 bits (128), Expect = 4e-07
Identities = 67/260 (25%), Positives = 83/260 (31%), Gaps = 21/260 (8%)
Query: 316 TDPLPPGQPQRIP----LPGQPLQ----PQPILTPGQPQKIPTPGQHQPILTPGHSQPIP 367
T P PP P P P+ P P TP P I T P TP S P
Sbjct: 1420 TTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP--ISTTTTPPPTTTP--SPPTT 1475
Query: 368 TPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRP-GQPMSP 426
TP P P P TP P TP P T PI P LPP P +P
Sbjct: 1476 TPSPP-TTTPSPPTTTTTTPPPTTTPSPP-TTTPITPPASTTTLPPTTTPSPPTTTTTTP 1533
Query: 427 QLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLAR 486
T P P+ PP + P PP + + PP + P
Sbjct: 1534 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP---PTTTTTPPPTTTPSPPTTTTPSPPT 1590
Query: 487 LPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYS 546
+ P + TT P T TP+ + T P S + P+ T +
Sbjct: 1591 ITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650
Query: 547 ATFSCKPSGAASVDLRVPSP 566
+ PS + PSP
Sbjct: 1651 PPPTTTPSPPTTT---TPSP 1667
Score = 50.1 bits (118), Expect = 6e-06
Identities = 75/344 (21%), Positives = 96/344 (27%), Gaps = 24/344 (6%)
Query: 71 PSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQTLLQEAQVLQ 130
P + +P P+ P T P T+ P S + T
Sbjct: 1440 PPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT 1499
Query: 131 GSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPE--LSHKST 188
SP P+ L P + P TT P P + T
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTT-----------TTPPPTTTPSPPTTTPIT 1548
Query: 189 AAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSR 248
S+ P + P T P + PS S +T+ P P +
Sbjct: 1549 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT 1608
Query: 249 LAAPPLGSTTLPSTWTA---PQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMP 305
PP +T P T T P S T P+ +P P + P P P
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1668
Query: 306 RREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQP-QKIPTPGQHQPILTPGHSQ 364
P T P P P P P TP P TP P +
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM 1728
Query: 365 PIPTPGQ-PLPPQ------PIPTPGRPLTPQPIPTPGRPLTPQP 401
P+P P PP P T PLT P+P P T P
Sbjct: 1729 TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/262 (22%), Positives = 80/262 (30%), Gaps = 18/262 (6%)
Query: 324 PQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQ-----PILTPGHSQPIPTPGQPLPPQPI 378
P P Q PI T PTP Q PI T P PTP P
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4061
Query: 379 P-TPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLP 437
P T +TP P PT + T PI P P P +P T P P
Sbjct: 4062 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTP 4119
Query: 438 QPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPR-SRLPIRLLRGLLARLPGGASPRAA 496
P G P +++ P P ++ P + +P
Sbjct: 4120 TP---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170
Query: 497 AAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSATFSCKPSGA 556
T + T TP T GPP ++ I E+ + P + + S S
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 4230
Query: 557 ASVDLRVPSPKPRALSRSRRYP 578
+ + S P A+ + P
Sbjct: 4231 LTESTTLLSTLPPAIEMTSTAP 4252
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/206 (24%), Positives = 62/206 (30%), Gaps = 14/206 (6%)
Query: 206 PPRTRLPSGSQAPSAAHPKRL--SDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTW 263
PP T PS + P S T+ P P + PP +TTLP T
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639
Query: 264 T-APQSRLTARP----------SRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYP 312
T +P T P + +P P I + P P P P
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699
Query: 313 LRGTDPLPPGQPQRIPLPGQPLQPQPI-LTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQ 371
T P P P P P +T P P+P P + P
Sbjct: 1700 SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT 1759
Query: 372 PLPPQPIPTPGRPLTPQPIPTPGRPL 397
PLPP P P + TP PL
Sbjct: 1760 PLPPSITPPTFSPFSTTTPTTPCVPL 1785
Score = 37.7 bits (86), Expect = 0.032
Identities = 47/198 (23%), Positives = 60/198 (30%), Gaps = 7/198 (3%)
Query: 337 QPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIP-TPGRPLTPQPIPTPGR 395
QP + PTP PI T P PTP P P T +TP P PT +
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940
Query: 396 PLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPL---LPPGQPKSAGRP 452
T PI P P P +P T P P P P P +
Sbjct: 1941 TPTTTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1998
Query: 453 LQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACT-TMKGWPAAT 511
+ P P ++ + P + + P T T G T
Sbjct: 1999 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2058
Query: 512 MTPAETSPTMGPPDASAG 529
TP T+ T+ P G
Sbjct: 2059 TTPITTTTTVTPTPTPTG 2076
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 80.1 bits (196), Expect = 6e-15
Identities = 158/629 (25%), Positives = 216/629 (34%), Gaps = 97/629 (15%)
Query: 8 PQRSPDPTFRSSTRHSGKLE-----PMEATAHLLRKQCPSRLNSPAWEASGLHWSSLDSP 62
P+ SP ++R S E P+ HL R S L+ P E S SP
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE-------SPLSP 505
Query: 63 VGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLS-------LTSLPREAAVNF 115
P + SP P A E + PLS L+ P E +
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP 565
Query: 116 SYRSQTLLQ--EAQVLQGSPELLPRSPKPSGLQRLAP----------EEATALPLRRLCH 163
+ L E + PE P SP P + P EE+ P
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 164 LSLMEKDLGTTAHPRGFP-----ELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAP 218
LS +D + P P E+S S SR S P S PP P+ S P
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT-SPPP 684
Query: 219 SAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQ-SRLTARPSRS 277
A+ + TS SP P L + PL + L PQ + P S
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
Query: 278 PEPQIRESEQRDPQLRRKQQRWKEPLMPRREE----------------KYPLRGTDP--- 318
P P+ R + Q + L P+ EE + P P
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804
Query: 319 -LPPG--QPQRIPLPGQP----------LQPQ---PILTPGQPQKIPTPGQHQPILTPGH 362
L P +P P+P +P L PQ P L+P + +P +P L+P
Sbjct: 805 HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP 864
Query: 363 SQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQ 422
+P PGQ P+ +P P P P G P +P + P P LP L L G+
Sbjct: 865 EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP--LPEELPLSPSGE 922
Query: 423 P-MSPQLRQTQGLPLP-QPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLL 480
P +SPQL LP P P++ P + PL L A+ SDP +P L
Sbjct: 923 PSLSPQLMPPDPLPPPLSPIITAAAPPALS-PLGELEYPFGAKGDSDPESP--------L 973
Query: 481 RGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAES 540
+ P P A CT + P + P+ SP +GP ++ + + S
Sbjct: 974 AAPILETPISPPPE----ANCTDPEPVPPMILPPSPGSP-VGP---ASPILMEPLPPQCS 1025
Query: 541 PSATYSATFSCKPSGAAS---VDLRVPSP 566
P +S P S + L VPSP
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054
Score = 74.3 bits (181), Expect = 3e-13
Identities = 110/400 (27%), Positives = 152/400 (38%), Gaps = 48/400 (12%)
Query: 92 TALHQKKLCPLSLTSLPR-EAAVNFSYRSQTLLQEAQVLQGSPELLPRSPKPSGLQRLAP 150
T++ K+ PL + P +A V + + L E L PE P SP P
Sbjct: 402 TSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSP--------PP 453
Query: 151 EEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTR 210
EE+ P LS ++L + PE H S S S P S PP
Sbjct: 454 EESPTSPPPEASRLSPPPEELPASP----LPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 211 LP------SGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWT 264
P S P + P + L+ A P S L+ PP LP++
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP---EELPTSPP 566
Query: 265 APQSRLTARPSRSP-EPQIRESEQR-DPQLRRKQQRWKE-PLMPRREEKYPLRGTDPLPP 321
SRL+ P SP P ES P+ R ++E PL P EE PL PP
Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES-PLS-----PP 620
Query: 322 GQPQRIPLPGQ--PLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIP 379
+ R+ P + P+ P P +P P + P+++ P +P P PP+ P
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP-PPEESP 679
Query: 380 TPGRPLTPQPIPTP-GRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQ 438
T P + P P P +P P P P PP L MS L ++ LPLP+
Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASP---PPEDSL------MSLPLEESPLLPLPE 730
Query: 439 PLLPPGQPKSAGRPLQPLPPGPDARSISDPP--APRSRLP 476
P P+S G L P P P + P +P++ P
Sbjct: 731 E--PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
Score = 66.6 bits (161), Expect = 6e-11
Identities = 65/223 (29%), Positives = 89/223 (39%), Gaps = 29/223 (13%)
Query: 318 PLPPGQPQRIPLPGQPLQPQ-PILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQ 376
PL Q P PL + P+L P + + P + P P + + P + LP
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
Query: 377 PIPTP---GRPLTPQPIPTPGR--PLTPQPIQMPGRPLRLPPPLRLLRPGQ--PMSPQLR 429
P+P RPL P+ P PL+P P P PL P L P + P SP L
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP----LSPPEESPPSPAL- 532
Query: 430 QTQGLPLPQ--PLLPPGQPKSAGRPLQPLP--PGPDARSISDPPAPRSRLPIRLLRGLLA 485
+T P P+ PL PP + P + LP P P+A +S PP P
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP--------- 583
Query: 486 RLPGGASPRAAAAAACTTMKGWPAATMT-PAETSPTMGPPDAS 527
P SP + A + + ++ P E SP PP+AS
Sbjct: 584 --PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624
Score = 63.5 bits (153), Expect = 5e-10
Identities = 118/457 (25%), Positives = 171/457 (37%), Gaps = 66/457 (14%)
Query: 47 PAWEASGLHWSSLDSPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTS 106
P A L S +G L Q++ P V +A E + HQ PL++ +
Sbjct: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDP---AVSSEATEGPSTHQGG--PLAIGT 4053
Query: 107 LPREAAVNFSYRSQTLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSL 166
P A +L ++Q+L P+ P+PS LQ P LP ++ +SL
Sbjct: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQ---PQPQPSSLQLQPP---LRLPGQQQQQVSL 4107
Query: 167 MEKDLGTTAHPRGFPELSHKSTAAASSRQ---SRPRVRSASLP-PRTRLPSGSQAPSAAH 222
+ TA +L S++ ASS ++P V P T+ G Q P
Sbjct: 4108 LH-----TAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER 4162
Query: 223 PKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQI 282
P + + P P +S P +G +P T Q R + + PQ+
Sbjct: 4163 PMQ------NNTGPQPPKPGPVLQSGQGLPGVG--IMP---TVGQLRAQLQGVLAKNPQL 4211
Query: 283 RE-SEQRDPQLRR--KQQRWKEPLMPRREEKYPLRGTDPLPPG-----QPQRIPLPGQPL 334
R S Q+ QL+ Q++ ++ R+ Y GT P QPQ PG
Sbjct: 4212 RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQT 4271
Query: 335 QPQPILTPGQ----PQKIPTPG---QHQPILTPGHSQPIPT-PGQPLPPQPIPTPGRPLT 386
P L G P ++P P P+L P H P P+ P +P P +P+P L
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331
Query: 387 PQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQP 446
+ P P TP+ P P PPP R+ P + QL T P PP
Sbjct: 4332 TEAQLPPTHPGTPK----PQGPTLEPPPGRV----SPAAAQLADTLFSKGLGPWDPPDNL 4383
Query: 447 KSAGRPLQ-PLPPG----------PDARSISDPPAPR 472
+P Q L PG P+A +S PR
Sbjct: 4384 AETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPR 4420
Score = 53.1 bits (126), Expect = 7e-07
Identities = 77/292 (26%), Positives = 101/292 (34%), Gaps = 52/292 (17%)
Query: 252 PPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKY 311
P LG PS+ T P P + Q +PQ L R +E
Sbjct: 2302 PNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ--------SPGLGLRPQEPP 2353
Query: 312 PLRGTDPLPPGQPQRIPLPGQPLQP--QPILTPGQPQKIPTPGQHQPILTPGHSQPIPTP 369
P + P PP P I PG P QP LTP +PQ P P + L P P
Sbjct: 2354 PAQALAPSPPSHPD-IFRPGSYTDPYAQPPLTP-RPQ--PPPPESCCALPPRSLPSDPFS 2409
Query: 370 GQPLPPQPIPTPGRPLTPQPI------PTPGRP--LTPQPI-QMPGRPLRLPPPLRLLRP 420
P PQ + PLTP+P+ P+P P +P P + P RP P L +P
Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469
Query: 421 GQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLL 480
+P P++ G L G P + LP GP
Sbjct: 2470 PRPQPPEVAFKAGSLAHTSLGAGGFPAA-------LPAGPAGE----------------- 2505
Query: 481 RGLLARLPGGASPRAAAAAACTTMKGWPAA---TMTPAETSPTMGPPDASAG 529
L A++P G P + G P+ T A P++ PP G
Sbjct: 2506 --LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
Score = 51.2 bits (121), Expect = 3e-06
Identities = 87/342 (25%), Positives = 120/342 (35%), Gaps = 73/342 (21%)
Query: 302 PLMPRREEKYPLRGTDPLPPGQPQRIPLPG-----------------------QPLQPQP 338
PL PR P P P G P + P+ G QP P P
Sbjct: 2184 PLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDP 2243
Query: 339 ILTPGQPQ----KIP-TPG-----QHQPILTP---GHSQPI------------PTPGQP- 372
L P P +P +PG +P+L+P G S+ P+ G P
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPN 2303
Query: 373 LPPQPIPTPGRPLTPQPIPTPG---RPLTPQPIQM----PGRPLR--LPPPLRLLRPGQP 423
L P+ G L + TP PLTP+ Q+ PG LR PPP + L P P
Sbjct: 2304 LGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPP 2363
Query: 424 MSPQLRQTQGL--PLPQPLL-----PPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLP 476
P + + P QP L PP P + LP P +R + P + S
Sbjct: 2364 SHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQS 2423
Query: 477 IRLLRGLLAR--LPGGASPRAAAAAACTTMKGWPAA--TMTPAETSPTMGPPDASAGFSI 532
R L A P +PR + + P + P P PP+ + F
Sbjct: 2424 PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVA--FKA 2481
Query: 533 GEIAAAESPSATYSATFSCKPSGAASVDLRVPSPKPRALSRS 574
G +A + + A P+G + +VPS +P RS
Sbjct: 2482 GSLAHTSLGAGGFPAALPAGPAG--ELHAKVPSGQPPNFVRS 2521
Score = 48.1 bits (113), Expect = 2e-05
Identities = 132/536 (24%), Positives = 189/536 (35%), Gaps = 108/536 (20%)
Query: 36 LRKQCPSRLNSPAWEASGLHWSSLDSPV-------GSMQALRPSAQHSWSPEPSV-VPDQ 87
L+ +CPS N E+ G+ P+ S +AL + + PS P+
Sbjct: 2245 LKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNL 2304
Query: 88 AWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQTLLQEAQVLQGSPELLPRSPKPSGLQR 147
+ D+ L L L + +++ + +QV SP L R +P Q
Sbjct: 2305 GFVDSPSSGTHLGGLELKTPD-------VFKAPLTPRASQVEPQSPGLGLRPQEPPPAQA 2357
Query: 148 LAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPP 207
LAP + + R G+ P P L+ + Q P +LPP
Sbjct: 2358 LAPSPPSHPDIFRP----------GSYTDPYAQPPLTPRP-------QPPPPESCCALPP 2400
Query: 208 RT-------RLPSGSQAPSAAH----PKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGS 256
R+ R+P+ Q+ S++ P+ LS P ++SPDP SR PP
Sbjct: 2401 RSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR---PP--- 2454
Query: 257 TTLPSTWTAPQSRLTARP-SRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRG 315
+ PQSR P + P PQ P++ K + L
Sbjct: 2455 -------SRPQSRDPFAPLHKPPRPQ-------PPEVAFKAGSLAHTSLGAGGFPAAL-- 2498
Query: 316 TDPLPPGQPQRIPLP-GQPLQPQPILTPGQPQKIPTPGQ-----HQPILTPGHSQPIPTP 369
P P +P GQP P + +PG + TP Q + P P+P P
Sbjct: 2499 --PAGPAGELHAKVPSGQP--PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP 2554
Query: 370 GQPLPPQ-------PIPTPGRP-LTPQPIPT-----PGRPLTPQPIQMPGRPLRLPP--P 414
G P PP P PT G+P T + T G PL P G L P P
Sbjct: 2555 GLP-PPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSS-GSTGESYGLSPLRP 2612
Query: 415 LRLLRPGQP------MSPQLRQTQGLPLP-QPLLPPGQPKSAGRPLQPLP----PGPDAR 463
+L P P +S Q G+ P + PG + LP PG
Sbjct: 2613 PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGL 2672
Query: 464 SISDPPAPRSRLPIR--LLRGLLAR--LPGGASPRAAAAAACTTMKGWPAATMTPA 515
S ++ R R +R L+R + R L AAAA A W A +PA
Sbjct: 2673 SQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728
Score = 46.2 bits (108), Expect = 9e-05
Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 50/230 (21%)
Query: 325 QRIPLPGQPLQPQPILTP-GQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGR 383
Q P+ + P+P TP +P + Q QP GH T QP P P+ +
Sbjct: 364 QHTPVCSRFSPPEPGDTPTDEPDALYVACQGQP--KGGHV----TSMQPKEPGPLQCEAK 417
Query: 384 PL------------------TPQPIPTPGRPLTPQPIQMPGRP----LRLPPPLRLLRPG 421
PL P P PL+P P + P P RL PP L P
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEEL-PA 476
Query: 422 QPMSPQLRQTQGL---PL-PQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPI 477
P+ L ++ L PL P P P P P PL P + PP+P P+
Sbjct: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL 536
Query: 478 RLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDAS 527
SP A+ + P + P E PT PP+AS
Sbjct: 537 --------------SPPPEASPLSPPFEESPLS--PPPEELPTSPPPEAS 570
Score = 43.1 bits (100), Expect = 8e-04
Identities = 65/234 (27%), Positives = 90/234 (38%), Gaps = 29/234 (12%)
Query: 320 PPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQP----IPTPGQ---P 372
P Q + P QP+ +P+ PQ P PG P+L G P +PT GQ
Sbjct: 4145 PGSMTQNLLGPQQPMLERPMQNNTGPQP-PKPG---PVLQSGQGLPGVGIMPTVGQLRAQ 4200
Query: 373 LPPQPIPTPG-RPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQT 431
L P R L+PQ L + +Q + +R PP + PG SP
Sbjct: 4201 LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ-SQAVRQTPPYQ--EPGTQTSP----L 4253
Query: 432 QGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGA 491
QGL QP L G P PLQ L GP + PAP L + G + P +
Sbjct: 4254 QGLLGCQPQLG-GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPS 4312
Query: 492 SPR---------AAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIA 536
SP+ + ++ T + P TP PT+ PP + ++A
Sbjct: 4313 SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Score = 38.1 bits (87), Expect = 0.025
Identities = 61/239 (25%), Positives = 84/239 (35%), Gaps = 45/239 (18%)
Query: 245 PRSRLAAPPLGSTTLPSTWTAPQSRLTARPS------------------RSPEPQIRESE 286
P S+L+ P LG + PS + A PS R+P P +
Sbjct: 2752 PPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQ 2811
Query: 287 QRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQ 346
Q+ QL ++QQ M ++ + P PG G PL PG +
Sbjct: 2812 QQQQQLWQQQQATAATSM-----RFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGE 2866
Query: 347 KIPTPG--------QH--QPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRP 396
+P P +H Q L PG + P P G P P+ P P P G
Sbjct: 2867 PVPGPAGPAQFIELRHNVQKGLGPGGT-PFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
Query: 397 LTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSA---GRP 452
++ P Q P PP L +P T+G LP L +P S+ GRP
Sbjct: 2926 VSGLPPQKPS-----APPAPELNNSLHPTP---HTKGPTLPTGLELVNRPPSSTELGRP 2976
Score = 36.6 bits (83), Expect = 0.071
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 18/123 (14%)
Query: 329 LPGQPLQPQPILTPGQPQKIPTPG---QH-----------QPILTPGHSQPIPTPGQPLP 374
LPG L+ Q + Q+ P P QH + + P +P P P PL
Sbjct: 4864 LPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS-PLA 4922
Query: 375 PQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQ---PMSPQLRQT 431
P P P PL P P P P+ + P P R P + P+L++
Sbjct: 4923 PSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKW 4982
Query: 432 QGL 434
+G+
Sbjct: 4983 KGV 4985
Score = 33.1 bits (74), Expect = 0.79
Identities = 38/138 (27%), Positives = 52/138 (37%), Gaps = 26/138 (18%)
Query: 164 LSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHP 223
LSL++++ P P H T S+ VR S PP PS +P A P
Sbjct: 4876 LSLLKQE-----SPAPEPPTQHSYTYNVSNLD----VRQLSAPPPEE-PSPPPSPLAPSP 4925
Query: 224 KRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIR 283
A+P +P L PL +PS S +ARP P
Sbjct: 4926 ------------ASP---PTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
Query: 284 ESEQRDPQLRR-KQQRWK 300
+ R P+L++ K RWK
Sbjct: 4971 GEDSRPPRLKKWKGVRWK 4988
Score = 32.0 bits (71), Expect = 1.8
Identities = 54/198 (27%), Positives = 64/198 (32%), Gaps = 30/198 (15%)
Query: 373 LPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQ 432
+PPQP P P G P TP + PP + P P L+
Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLK--- 2162
Query: 433 GLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPG-GA 491
LP P P Q P PL P P AP + P G A+ P GA
Sbjct: 2163 -LPPQVPAQVPSQDPFGLAPAYPLEP-------RFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
Query: 492 SPRAAAAAA---CTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSAT 548
S R A TT G P P+ P + P S+ +A ESP
Sbjct: 2215 SSRPGAGQPGEFHTTPPGTP--RHQPSTPDPFLKPRCP----SLDNLAVPESPGV----- 2263
Query: 549 FSCKPSGAASVDLRVPSP 566
G AS L P P
Sbjct: 2264 ----GGGKASEPLLSPPP 2277
Score = 31.6 bits (70), Expect = 2.3
Identities = 38/143 (26%), Positives = 58/143 (40%), Gaps = 38/143 (26%)
Query: 395 RPLTPQPIQMPGRPLRLPPPLRLLRP------GQPMSPQLRQTQGL-PLPQPLLPPG--- 444
+PLTP+P ++ RL + LR + + QL+Q L PL +P +
Sbjct: 4516 KPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSL 4575
Query: 445 -QPKSAGRPLQ------------PLPPGPDARS-------ISDPPAPRSRLP-------- 476
P +G P+ LP GPD S +S+PP P S LP
Sbjct: 4576 FAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQ 4635
Query: 477 IRLLRGLLARLPGGASPRAAAAA 499
+++ G+ G P+ AA+A
Sbjct: 4636 QKMVNGVTPSEELGEHPKDAASA 4658
Score = 30.8 bits (68), Expect = 3.9
Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 17/82 (20%)
Query: 384 PLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPP 443
P +P P P PL P P P PL P L P P+P PL
Sbjct: 4909 PPPEEPSPPPS-PLAPSPASPPTEPLVELPTEPLAEP--------------PVPSPLPLA 4953
Query: 444 GQPKSAGRPLQPLPP--GPDAR 463
P+SA + PP G D+R
Sbjct: 4954 SSPESARPKPRARPPEEGEDSR 4975
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 79.7 bits (195), Expect = 7e-15
Identities = 164/646 (25%), Positives = 222/646 (34%), Gaps = 91/646 (14%)
Query: 15 TFRSSTRHSGKLEPMEATA--HLLRKQCPSRLNSPAWEASGLHWSSLDSPVGSM-----Q 67
T+ + G EP E A HLL P+ S A + S+ DS GS Q
Sbjct: 576 TYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASD------STFDSGQGSTVYSDSQ 629
Query: 68 ALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQTLLQEAQ 127
+ + S + + P Q + + + P SL SL +Y+ T
Sbjct: 630 SSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLG-------AYQQPTAAPGLP 682
Query: 128 VLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKS 187
V GS +P P LQ+ P+ A + + M G A P P +
Sbjct: 683 V--GS---VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQP 737
Query: 188 TAAASSRQSRPRVRSASLPPRTR--LPSGSQ--APSAAHPKRLSDLLLTSRAAAPGWRSP 243
T +P V +PP L SQ AP+ P ++ L A P P
Sbjct: 738 TPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797
Query: 244 DPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPL 303
P P G LP A TA P PQ P L P
Sbjct: 798 IPVVPPITPLAGIDGLPP---ALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPP-ASPA 853
Query: 304 MPRREEKYPLRGTDPLP-------PGQPQRIPL-----PG----------QPLQPQPILT 341
+P + K P PL P P IPL PG L QP+
Sbjct: 854 LPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYP 913
Query: 342 PGQPQKIPT---PGQHQPILTPGHSQPIPT-PGQP-LPPQPIPTPGRPLTPQPI--PTPG 394
PQ PT P H + + P P P QP LPPQP+ P L PQP+ P P
Sbjct: 914 AAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973
Query: 395 RPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQ 454
RP PQP+ +P +P+ P P+ +P P+ P+ Q P PG G P
Sbjct: 974 RP--PQPV-LPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAP 1030
Query: 455 ---------PLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMK 505
P P P A +S PP P LP LL + P + +A+ + T
Sbjct: 1031 YAVDVAAQVPTVPVPPAAVLS-PPLPEVLLP--AAPELLPQFPSSLATVSASVQSVPTQ- 1086
Query: 506 GWPAATMTPAETSPTMGPPDASAGFSIGEIAA------AESPSATYSATFSCKPSGAASV 559
AT+ P P G P ++ ++ S SC+ G +
Sbjct: 1087 ---TATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSD- 1142
Query: 560 DLRVPSPKPRALSRSRRYPWRRSADRCAKKPWRSGPRSAQRRNAVS 605
V S K + S + R R A+K R R+ R+ S
Sbjct: 1143 ---VTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERAS 1185
Score = 46.6 bits (109), Expect = 7e-05
Identities = 65/256 (25%), Positives = 82/256 (32%), Gaps = 42/256 (16%)
Query: 318 PLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQP 377
P P PLP L P+ P K + QP Q + G PP
Sbjct: 1322 PAPEAPESSPPLPLSSLPPEAS-QDSAPYKDQLSSKEQPSFLASQ-QLLSQAGPSNPPGA 1379
Query: 378 IPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLP 437
P P P +P P P MP P + G P +PQ T L
Sbjct: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPE-----PASGTASQAGGPGTPQ-GLTSELETS 1433
Query: 438 QPLLPPGQPKSAGRPL----QPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASP 493
QPL + A +PL P P P+A S D APR LP P P
Sbjct: 1434 QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLP-----------PPAPEP 1482
Query: 494 RAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAES--PSATYSATFSC 551
+ G P P +G P ++G ++ A S PS T
Sbjct: 1483 --------SPHSGTP---------QPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPP 1525
Query: 552 KPSGAASVDLRVPSPK 567
+P A D P P+
Sbjct: 1526 QPPSALESDGEGPPPR 1541
Score = 46.6 bits (109), Expect = 7e-05
Identities = 67/239 (28%), Positives = 87/239 (36%), Gaps = 35/239 (14%)
Query: 243 PDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKE- 301
P P + ++PPL ++LP P++ + P + Q+ EQ P QQ +
Sbjct: 1322 PAPEAPESSPPLPLSSLP-----PEASQDSAPYKD---QLSSKEQ--PSFLASQQLLSQA 1371
Query: 302 -PLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTP 360
P P PL + P PQ P P+P G + PG Q + +
Sbjct: 1372 GPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEP--ASGTASQAGGPGTPQGLTSE 1429
Query: 361 -GHSQPI-PTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLL 418
SQP+ T PL QP+ P TP P + + P PL P P
Sbjct: 1430 LETSQPLAETHEAPLAVQPLVVGLAPCTPAP-----EAASTRDASAPREPLPPPAPEPSP 1484
Query: 419 RPGQPMSPQLRQTQGLPLPQPLLPP--GQPKSAGRPLQPLPPGPDARSISDPPAPRSRL 475
G P P L Q P PLLP G A L P GP PP P S L
Sbjct: 1485 HSGTP-QPALGQ------PAPLLPAAVGAVSLATSQLPSPPLGPTV-----PPQPPSAL 1531
Score = 43.1 bits (100), Expect = 8e-04
Identities = 64/238 (26%), Positives = 84/238 (35%), Gaps = 33/238 (13%)
Query: 190 AASSRQSRPRVRSASLPPRTR---LPSGSQAPSAAHPKRLSDLLLTSRAAA--PGWRSPD 244
A + +S P + +SLPP P Q S P L+ L S+A P P
Sbjct: 1323 APEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382
Query: 245 PRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRD----PQLRRKQQRWK 300
P + ++PP+ T LP AP + S PEP + Q PQ +
Sbjct: 1383 PLAP-SSPPV--TALPQDGAAPAT------STMPEPASGTASQAGGPGTPQGLTSELETS 1433
Query: 301 EPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQP--QKIPTPGQHQPIL 358
+PL E PL PL G P P + + P +P P P H
Sbjct: 1434 QPLAETHEA--PL-AVQPLVVGLAPCTPAP-EAASTRDASAPREPLPPPAPEPSPHS--- 1486
Query: 359 TPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTP--GRPLTPQPIQMPGRPLRLPPP 414
P P GQP P P L +P+P G + PQP PPP
Sbjct: 1487 ----GTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPP 1540
Score = 39.3 bits (90), Expect = 0.011
Identities = 115/515 (22%), Positives = 169/515 (32%), Gaps = 121/515 (23%)
Query: 1 MMARPVDPQRSPDPTFRSSTRHSGKLEPMEATAHLL--RKQCPSRLNSPAWEASGLHWSS 58
M++ D R DP G P +T L + S+ N+P ++ + LH
Sbjct: 1260 MLSEDTDADRGSDP---------GTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGK 1310
Query: 59 LDSPVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFS-Y 117
+ P A+H P P PL L+SLP EA+ + + Y
Sbjct: 1311 ------RWFIICPVAEHPAPEAPESSP---------------PLPLSSLPPEASQDSAPY 1349
Query: 118 RSQTLLQEAQVLQGSPELL----PRSPKPSGLQRLAPEE--ATALPLRRLCHL-SLMEKD 170
+ Q +E S +LL P +P + LAP TALP S M +
Sbjct: 1350 KDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEP 1409
Query: 171 LGTTAHPRGFPELSHKSTAAASSRQSRPRVRSA---------SLPPRTRLPSGSQAPSAA 221
TA G P T+ + Q A L P T P + A+
Sbjct: 1410 ASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDAS 1469
Query: 222 HPKRLSDLLLTSRAAAPGWRSPDPR-------------------SRLAAPPLGSTTLPST 262
P+ L + +P +P P S+L +PPLG T P
Sbjct: 1470 APRE--PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
Query: 263 WTAPQSRLTARPSRSPEPQI----RESEQRDPQLRRKQQRWKEP-----------LMPRR 307
+A +S P P++ + D +LR + P + R
Sbjct: 1528 PSALES-----DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRD 1582
Query: 308 EEKYPLRGTDP----------LPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPI 357
PLRG P LPP + + G+ PQP++ + + PT G +
Sbjct: 1583 FTLEPLRGDQPRSEVCGGDLALPPVPKEAV--SGRVQLPQPLVE--KSELAPTRG---AV 1635
Query: 358 LTPGHSQPIPTPGQPLPPQPIPTPGR---------PLTPQPIPTPGRPLTPQPIQM---- 404
+ G S + P GR P PQ +P RP +P
Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695
Query: 405 PGRPLRLPPPLRL-LRPGQPMSPQLRQTQGLPLPQ 438
G PPP + GQ PQ + L P+
Sbjct: 1696 AGESSAEPPPSDMGTVGGQASHPQTLGARALGSPR 1730
Score = 33.1 bits (74), Expect = 0.79
Identities = 58/202 (28%), Positives = 68/202 (33%), Gaps = 44/202 (21%)
Query: 382 GRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLL 441
GR P + PGR P + P P P R LR S Q
Sbjct: 6 GRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEE------------ 53
Query: 442 PPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRL--LRGLLARLPGGASPRAAAAA 499
PPG + PGP PP P R + L R L+A G P A A A
Sbjct: 54 PPGLEAAEA-------PGP------QPPQPLQRRVLLLCKTRRLIAERARG-RPAAPAPA 99
Query: 500 ACTTMKGWPAATMTPAETSP----TMGP-PDASAGFSIGEIAAAESPSATYSATFSCKPS 554
A G P A PA+ P T P PD A A P +AT +
Sbjct: 100 ALVAQPGAPGA---PADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDE 156
Query: 555 GAASVDLRVPSPKPRALSRSRR 576
GAA P+P R+RR
Sbjct: 157 GAAEA-----KPEP---GRTRR 170
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 79.7 bits (195), Expect = 7e-15
Identities = 107/392 (27%), Positives = 135/392 (34%), Gaps = 51/392 (13%)
Query: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRLPSG-SQAPSAAHPKRLSDLLLTSRAAAPG 239
P + + S S + + PP + P+G + APS+A P T + PG
Sbjct: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG-------TPQLPTPG 211
Query: 240 WRSPDPRSRLAAPPLGSTTL------PSTWTAP------QSRLTARPSRSPEPQIRESEQ 287
P P S A PP GS T P TAP Q P R P P
Sbjct: 212 ---PTP-SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 267
Query: 288 RDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQK 347
P L+ +P P + PL G P P Q PL P PQP P Q +
Sbjct: 268 PHPPLQPLTGSAGQPSAPSHAQP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 326
Query: 348 IPTPGQHQPILTPGHSQ------------PIPTPGQPLPPQPIPTP---GRPLTPQP-IP 391
P P H+ P QPLPP P+ P P TP P +P
Sbjct: 327 GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLP 386
Query: 392 TPGRPLTPQPIQMP---GRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKS 448
P P + P LPPP L+P +S P P L+P QP
Sbjct: 387 APQAHKHPPHLSGPSPFSMNANLPPP-PALKPLSSLSTH-HPPSAHPPPLQLMPQSQP-- 442
Query: 449 AGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP 508
P P P +S + PP P S P L + + P P T P
Sbjct: 443 --LPSSPAQPPGLTQSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP 499
Query: 509 AATMTPAETSPTMGPPDASAGFSIGEIAAAES 540
+ + PA + PP + A S G IA S
Sbjct: 500 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 531
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/338 (24%), Positives = 117/338 (34%), Gaps = 44/338 (13%)
Query: 184 SHKSTAAASSRQSRPRVRSASLPPRTR------LPSGSQAPSAAHPKRLSDLLLTSRAAA 237
+ +S + S+ +S + + AS RT SG +PSAA T + +A
Sbjct: 20 TRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSA 79
Query: 238 PGWR----SPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLR 293
+ SP ++ + S T + T+ + T SR P E E D +
Sbjct: 80 KKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 139
Query: 294 RKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQ 353
+ +P ++ R T P P Q Q + + PT
Sbjct: 140 NDEGS-SDP----KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT 194
Query: 354 HQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPP 413
P P + +PTPG +P G P Q P P P +P ++ P
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP----VPHTHIQQAP 250
Query: 414 PLRLLRPGQPMSPQLRQTQGLPLPQPLLPP-----GQPKSAGRPLQPL----PPGPDARS 464
L RP P P P P P L P GQP + PL PPGP +
Sbjct: 251 ALHPQRPPSPHPPP------HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 304
Query: 465 IS------DPPAPRSRLPIRLLRGLLARLPGGASPRAA 496
PP P LP + +G + P G SP AA
Sbjct: 305 AGPLLQHPGPPQPFG-LPPQASQG---QAPLGTSPAAA 338
Score = 32.0 bits (71), Expect = 1.8
Identities = 43/169 (25%), Positives = 63/169 (37%), Gaps = 31/169 (18%)
Query: 182 ELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLL---------- 231
E K+ + + + R ++A S+AH RLSD L
Sbjct: 619 EAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF 678
Query: 232 ----TSRAAAPGWRSPD-----PRSRLAAPPLGSTT-------LPSTWTAPQSRLTARPS 275
T+ AA P + PD S A P + S T +P T P
Sbjct: 679 EPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGL 738
Query: 276 RSPEPQIRESEQRDPQLRRKQQR---WKEPLMPRREEKYPLRGTDPLPP 321
+ +P IRE E R+ ++R ++ R +E + P E K P DPL P
Sbjct: 739 YNVDPTIRERELREREIREREIRERELRERMKPGFEVKPP--ELDPLHP 785
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 79.7 bits (195), Expect = 7e-15
Identities = 107/392 (27%), Positives = 135/392 (34%), Gaps = 51/392 (13%)
Query: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRLPSG-SQAPSAAHPKRLSDLLLTSRAAAPG 239
P + + S S + + PP + P+G + APS+A P T + PG
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG-------TPQLPTPG 765
Query: 240 WRSPDPRSRLAAPPLGSTTL------PSTWTAP------QSRLTARPSRSPEPQIRESEQ 287
P P S A PP GS T P TAP Q P R P P
Sbjct: 766 ---PTP-SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821
Query: 288 RDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQK 347
P L+ +P P + PL G P P Q PL P PQP P Q +
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 880
Query: 348 IPTPGQHQPILTPGHSQ------------PIPTPGQPLPPQPIPTP---GRPLTPQP-IP 391
P P H+ P QPLPP P+ P P TP P +P
Sbjct: 881 GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLP 940
Query: 392 TPGRPLTPQPIQMP---GRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKS 448
P P + P LPPP L+P +S P P L+P QP
Sbjct: 941 APQAHKHPPHLSGPSPFSMNANLPPP-PALKPLSSLSTH-HPPSAHPPPLQLMPQSQP-- 996
Query: 449 AGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP 508
P P P +S + PP P S P L + + P P T P
Sbjct: 997 --LPSSPAQPPGLTQSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053
Query: 509 AATMTPAETSPTMGPPDASAGFSIGEIAAAES 540
+ + PA + PP + A S G IA S
Sbjct: 1054 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 1085
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/338 (24%), Positives = 117/338 (34%), Gaps = 44/338 (13%)
Query: 184 SHKSTAAASSRQSRPRVRSASLPPRTR------LPSGSQAPSAAHPKRLSDLLLTSRAAA 237
+ +S + S+ +S + + AS RT SG +PSAA T + +A
Sbjct: 574 TRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSA 633
Query: 238 PGWR----SPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLR 293
+ SP ++ + S T + T+ + T SR P E E D +
Sbjct: 634 KKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 693
Query: 294 RKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQ 353
+ +P ++ R T P P Q Q + + PT
Sbjct: 694 NDEGS-SDP----KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT 748
Query: 354 HQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPP 413
P P + +PTPG +P G P Q P P P +P ++ P
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP----VPHTHIQQAP 804
Query: 414 PLRLLRPGQPMSPQLRQTQGLPLPQPLLPP-----GQPKSAGRPLQPL----PPGPDARS 464
L RP P P P P P L P GQP + PL PPGP +
Sbjct: 805 ALHPQRPPSPHPPP------HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 858
Query: 465 IS------DPPAPRSRLPIRLLRGLLARLPGGASPRAA 496
PP P LP + +G + P G SP AA
Sbjct: 859 AGPLLQHPGPPQPFG-LPPQASQG---QAPLGTSPAAA 892
Score = 32.0 bits (71), Expect = 1.8
Identities = 43/169 (25%), Positives = 63/169 (37%), Gaps = 31/169 (18%)
Query: 182 ELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLL---------- 231
E K+ + + + R ++A S+AH RLSD L
Sbjct: 1173 EAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF 1232
Query: 232 ----TSRAAAPGWRSPD-----PRSRLAAPPLGSTT-------LPSTWTAPQSRLTARPS 275
T+ AA P + PD S A P + S T +P T P
Sbjct: 1233 EPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGL 1292
Query: 276 RSPEPQIRESEQRDPQLRRKQQR---WKEPLMPRREEKYPLRGTDPLPP 321
+ +P IRE E R+ ++R ++ R +E + P E K P DPL P
Sbjct: 1293 YNVDPTIRERELREREIREREIRERELRERMKPGFEVKPP--ELDPLHP 1339
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 79.7 bits (195), Expect = 7e-15
Identities = 107/392 (27%), Positives = 135/392 (34%), Gaps = 51/392 (13%)
Query: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRLPSG-SQAPSAAHPKRLSDLLLTSRAAAPG 239
P + + S S + + PP + P+G + APS+A P T + PG
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG-------TPQLPTPG 765
Query: 240 WRSPDPRSRLAAPPLGSTTL------PSTWTAP------QSRLTARPSRSPEPQIRESEQ 287
P P S A PP GS T P TAP Q P R P P
Sbjct: 766 ---PTP-SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821
Query: 288 RDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQK 347
P L+ +P P + PL G P P Q PL P PQP P Q +
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQP-PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 880
Query: 348 IPTPGQHQPILTPGHSQ------------PIPTPGQPLPPQPIPTP---GRPLTPQP-IP 391
P P H+ P QPLPP P+ P P TP P +P
Sbjct: 881 GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLP 940
Query: 392 TPGRPLTPQPIQMP---GRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKS 448
P P + P LPPP L+P +S P P L+P QP
Sbjct: 941 APQAHKHPPHLSGPSPFSMNANLPPP-PALKPLSSLSTH-HPPSAHPPPLQLMPQSQP-- 996
Query: 449 AGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP 508
P P P +S + PP P S P L + + P P T P
Sbjct: 997 --LPSSPAQPPGLTQSQNLPPPPASHPPTG-LHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053
Query: 509 AATMTPAETSPTMGPPDASAGFSIGEIAAAES 540
+ + PA + PP + A S G IA S
Sbjct: 1054 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 1085
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/338 (24%), Positives = 117/338 (34%), Gaps = 44/338 (13%)
Query: 184 SHKSTAAASSRQSRPRVRSASLPPRTR------LPSGSQAPSAAHPKRLSDLLLTSRAAA 237
+ +S + S+ +S + + AS RT SG +PSAA T + +A
Sbjct: 574 TRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSA 633
Query: 238 PGWR----SPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLR 293
+ SP ++ + S T + T+ + T SR P E E D +
Sbjct: 634 KKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 693
Query: 294 RKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQ 353
+ +P ++ R T P P Q Q + + PT
Sbjct: 694 NDEGS-SDP----KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT 748
Query: 354 HQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPP 413
P P + +PTPG +P G P Q P P P +P ++ P
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP----VPHTHIQQAP 804
Query: 414 PLRLLRPGQPMSPQLRQTQGLPLPQPLLPP-----GQPKSAGRPLQPL----PPGPDARS 464
L RP P P P P P L P GQP + PL PPGP +
Sbjct: 805 ALHPQRPPSPHPPP------HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 858
Query: 465 IS------DPPAPRSRLPIRLLRGLLARLPGGASPRAA 496
PP P LP + +G + P G SP AA
Sbjct: 859 AGPLLQHPGPPQPFG-LPPQASQG---QAPLGTSPAAA 892
Score = 32.0 bits (71), Expect = 1.8
Identities = 43/169 (25%), Positives = 63/169 (37%), Gaps = 31/169 (18%)
Query: 182 ELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLL---------- 231
E K+ + + + R ++A S+AH RLSD L
Sbjct: 1173 EAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF 1232
Query: 232 ----TSRAAAPGWRSPD-----PRSRLAAPPLGSTT-------LPSTWTAPQSRLTARPS 275
T+ AA P + PD S A P + S T +P T P
Sbjct: 1233 EPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGL 1292
Query: 276 RSPEPQIRESEQRDPQLRRKQQR---WKEPLMPRREEKYPLRGTDPLPP 321
+ +P IRE E R+ ++R ++ R +E + P E K P DPL P
Sbjct: 1293 YNVDPTIRERELREREIREREIRERELRERMKPGFEVKPP--ELDPLHP 1339
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 79.3 bits (194), Expect = 1e-14
Identities = 136/522 (26%), Positives = 173/522 (33%), Gaps = 139/522 (26%)
Query: 132 SPELLPRS-------PKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGT------TAHPR 178
SP LPR P P + AP LR SL+ DLG+ ++ P
Sbjct: 200 SPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRS----SLVPSDLGSPPAPHASSSPP 255
Query: 179 GFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPS----GSQAPSAAHPKRLSDLLLTSR 234
P L H S A + LPP LP+ SQ P ++ L L+L
Sbjct: 256 SDPPLFHCSDA----------LTPPPLPPSNNLPAHPGPASQPPVSSATMHLP-LVLGPL 304
Query: 235 AAAPGWRSPDPRSRLAAPPLGSTTLPSTWTA------PQSRLTARPSRSPEPQIRESEQR 288
AP P A P L S+ L + A P S L R R+ P S
Sbjct: 305 GGAPTVEGPG-----APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSL 359
Query: 289 DPQLRRKQQ--------RWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPIL 340
P RR ++ + P PRR R P P QP +P P QP+ P +
Sbjct: 360 RPSQRRPRRPPTVFRLLEGRGPQTPRRS-----RPRAPAPVPQPFSLPEPSQPILPSVLS 414
Query: 341 TPGQPQKIPT--PGQHQPILTPGHSQPIPTPGQPLPPQP-------IP---------TPG 382
G P P+ G + + H P PT PPQP +P PG
Sbjct: 415 LLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPG 474
Query: 383 RPLTPQ--------------------------------------PIPTPGRPLTPQPIQM 404
P P P P+P + L
Sbjct: 475 APAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF 534
Query: 405 PGRPLRLPPPLRLLRPGQPMSPQLRQTQ--------GLPLPQPLLP----------PGQP 446
PG LP PL L +P P SP L + G P P+PLLP PG+P
Sbjct: 535 PGMLGALPLPLSLGQP--PPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEP 592
Query: 447 KSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLP----GGASPRAAAAAACT 502
+ + L P P + + P AP S L L LLA P G S A +
Sbjct: 593 EGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFL-PLLALGPTAGDGEGSAEGAGGPSGE 651
Query: 503 TMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSAT 544
G ++P P PP A S A + PS T
Sbjct: 652 PFSG--LGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGT 691
Score = 77.8 bits (190), Expect = 3e-14
Identities = 115/449 (25%), Positives = 157/449 (34%), Gaps = 73/449 (16%)
Query: 135 LLPRSPKPSGLQRLAPEEATAL--PLRRLCHLSLMEKDLGTTAHPRG-----FPELSHKS 187
L P +P +G+ + E+ T L R+ ++ + + + TT P++ H
Sbjct: 79 LAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFH-- 136
Query: 188 TAAASSRQSRPRVR----------SASLPPRTRLPSGSQA------PSAAHPKRLSDLLL 231
T + +RP R SLPP PS SQA P P RL+D +
Sbjct: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEP--PSVSQAFPTLAGPGGLFPPRLADPVP 194
Query: 232 TSRAAAPGW--RSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPS---RSPEPQIRESE 286
+ +++P + R P PP S PS R + PS P P S
Sbjct: 195 SGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSP 254
Query: 287 QRDPQLRRKQQRWKEPLMPRREE--KYPLRGTDPLPPGQPQRIPLPGQPLQPQPILT-PG 343
DP L P +P +P + P +PL PL P + PG
Sbjct: 255 PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPG 314
Query: 344 QPQKIPTP-------GQHQPILTP----GHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPT 392
P + + QH P+ P G P P+ RP P PT
Sbjct: 315 APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP---PT 371
Query: 393 PGRPLTPQPIQMPGR-----PLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPK 447
R L + Q P R P +P P L P QP+ P + GLP P P G
Sbjct: 372 VFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFN 431
Query: 448 SAGRPLQPLPPGPDARSISDPPAPRSRLPIRL---LRGLLARLPGGASPRAAAAAACTTM 504
G LPP P S PP PR + L G L+ +PG +P
Sbjct: 432 LLGSDAH-LPP-PPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP----------- 478
Query: 505 KGWPAATMTPAETSPTMGPPDASAGFSIG 533
PAA+ P SP + P G G
Sbjct: 479 ---PAASKAPVVPSPVLQSPSEGLGMGAG 504
Score = 48.1 bits (113), Expect = 2e-05
Identities = 120/481 (24%), Positives = 153/481 (31%), Gaps = 108/481 (22%)
Query: 181 PELSHKSTAAASSRQSR--PRV------RSASLPPRTRLPSGSQAPSAAHPKRLSDLLLT 232
P SH S+ S R+ R P V R P R+R + + P S +L
Sbjct: 351 PSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILP 410
Query: 233 SRAAAPGWRSPDPR------------SRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEP 280
S + G +P P + L PP S+ P PQ R +PS
Sbjct: 411 SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP-----PQPRHPIQPSLPGTT 465
Query: 281 QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTD-------PLPP---GQPQRIPLP 330
S P K P++P + P G PLPP G+ P P
Sbjct: 466 S--GSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP 523
Query: 331 GQPLQPQPILTPGQPQKIPTP---GQHQP----------ILTPGHSQPIPTPGQPLPPQP 377
Q L PG +P P GQ P +LT G QP P P P P P
Sbjct: 524 EQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGP 583
Query: 378 IP--TPGRP-----LTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRP---------- 420
P PG P L +P P L P P P L PL L P
Sbjct: 584 GPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAE 643
Query: 421 ------GQP------MSPQLRQTQGLP--------------LPQPLLPPGQPKSAGRPLQ 454
G+P +SP L P L P P QP P Q
Sbjct: 644 GAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP-Q 702
Query: 455 PLPP---------GPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMK 505
P PP P A S+ P+ R P L L A L G S ++ A ++
Sbjct: 703 PGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLL 762
Query: 506 GWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPS 565
P + S +G G + ++ A SP A + P + L S
Sbjct: 763 QPPGPLL-----SGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPES 817
Query: 566 P 566
P
Sbjct: 818 P 818
Score = 34.3 bits (77), Expect = 0.35
Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 22/163 (13%)
Query: 328 PLPGQPLQPQPILTP--GQPQKIPT-----PGQHQPILTPGHSQPIPTPGQPLPPQPIPT 380
P G P QP + P G P T PG P +S P PL +
Sbjct: 687 PPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLG 746
Query: 381 PGRPLTPQPIPTPGRPLTPQPIQMPGRPLRL------PPPLRLLRPGQPMSPQLRQTQGL 434
LT P P P P+ L+L PPPL P++ L+ Q +
Sbjct: 747 DLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLS--EASSPLACLLQSLQ-I 803
Query: 435 PLPQPLLPPGQPKSAGRPLQPLPPGPDARSIS------DPPAP 471
P QP P P+S L+P P P +++ DPP P
Sbjct: 804 PPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVP 846
Score = 32.0 bits (71), Expect = 1.8
Identities = 58/216 (26%), Positives = 71/216 (32%), Gaps = 29/216 (13%)
Query: 214 GSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTAR 273
G+ PS L DL S P +P L + L +T P + T PQ + +
Sbjct: 644 GAGGPSGEPFSGLGDL---SPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSA 700
Query: 274 PSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKY--PLRGTDPL---------PPG 322
P P + DP K P R + PL G L P
Sbjct: 701 PQPGPPTSSVTTATTDPGA---SSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGA 757
Query: 323 QPQRIPLPGQPLQPQP--ILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQP----LPPQ 376
P + PG L Q L PG P P+ S IP P QP LPP+
Sbjct: 758 LPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIP-PEQPEAPCLPPE 816
Query: 377 PI-----PTPGRPLTPQPIPTPGRPLTPQPIQMPGR 407
P P RP P G P P P + GR
Sbjct: 817 SPASALEPEPARPPLSALAPPHGSPDPPVPELLTGR 852
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 77.0 bits (188), Expect = 5e-14
Identities = 61/181 (33%), Positives = 80/181 (44%), Gaps = 43/181 (23%)
Query: 302 PLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPG 361
P +PR P+ P+PP +P +P+P P+P + P P PG + PG
Sbjct: 239 PQLPRP----PVLPVPPMPP-RPPMVPMP-----PRPPIAPMPPMAPVPPGSRMAPVPPG 288
Query: 362 HSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPL-RLP--PPLRLL 418
P P P PP P P+ P P G P+ P P PG P+ R+P PP+ +
Sbjct: 289 ---PRMAPVPPWPPMAPVPPWPPMAPVP---TGPPMAPVP---PGPPMARVPPGPPMARV 339
Query: 419 RPGQPMSPQLRQTQGLPLPQPLLPPGQPKS---AGRPLQPLPPGPDARSISDPPAPRSRL 475
PG PM+P LPPG P + G P+ PLPPGP P PRS +
Sbjct: 340 PPGPPMAP--------------LPPGPPMAPLPPGPPMAPLPPGPPMA----PLPPRSHV 381
Query: 476 P 476
P
Sbjct: 382 P 382
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 72.8 bits (177), Expect = 9e-13
Identities = 91/290 (31%), Positives = 112/290 (38%), Gaps = 52/290 (17%)
Query: 277 SPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIP-------- 328
SPEP +E E R P + + P PL PLPP +P R P
Sbjct: 1240 SPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPET 1299
Query: 329 -------LPGQPL-QPQPILTPG---------QPQKIP-TPGQHQPILTPGHSQPIPTPG 370
+P +PL + P TPG + +P TPG P+ + +P
Sbjct: 1300 TDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQ 1359
Query: 371 QPLPPQPIPTPGRPLTPQPIP-TPGRPLTPQP-IQMPGRPLRLPP-PL----RLLRPGQP 423
P P P P L+ +P TPGR + P P PL LP PL R R G
Sbjct: 1360 VPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPL 1419
Query: 424 MSPQLRQTQGLPLPQPL-LP-----PGQPKSAGRPLQPLPPGPDARSISDPP-------A 470
SP L +T GLPLP PL LP P ++ R PLPP A S PP
Sbjct: 1420 ASPVLLET-GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGR 1478
Query: 471 PRSRLPIRL-LRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSP 519
PR P L L G L R P G AA + G P + P+ P
Sbjct: 1479 PRRSPPSMLSLDGPLVRPPAG----AALGRELLLLPGQPQTPVFPSTHDP 1524
Score = 60.8 bits (146), Expect = 4e-09
Identities = 80/302 (26%), Positives = 100/302 (33%), Gaps = 92/302 (30%)
Query: 252 PPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDP----QLRRKQQRWKEPLMPRR 307
PP PS P++ + PS PEP + P L + Q P P
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGG 1342
Query: 308 EEKYPLRG-------TDPLPPGQPQRIPLPGQPLQPQPI-LTPGQPQKI-PTPGQHQ-PI 357
E PL G + P PG P P P L + TPG+ PT + P+
Sbjct: 1343 EP--PLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPL 1400
Query: 358 LTP----------GHSQPIPTP-----GQPLP-----PQPIPTPGRPLTPQPIPTPGRPL 397
L P S P+ +P G PLP P P+ P PTP PL
Sbjct: 1401 LLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPL 1460
Query: 398 TPQPI--------QMPGRPLRLPPPLR-------------------LLRPGQPMSPQLRQ 430
P P+ + PGRP R PP + LL PGQP +P
Sbjct: 1461 LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520
Query: 431 TQ------------GLPLPQPLLPPGQPKSAGRP-----------------LQPLPPGPD 461
T G+P P P LPP P P + +PPGP
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580
Query: 462 AR 463
R
Sbjct: 1581 GR 1582
Score = 58.2 bits (139), Expect = 2e-08
Identities = 70/278 (25%), Positives = 97/278 (34%), Gaps = 24/278 (8%)
Query: 202 SASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLA--APPLGSTTL 259
S P P+G + P + R+ LL R R PD + L P+ S++
Sbjct: 479 SPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSS 538
Query: 260 PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPL 319
+ AP + R P P P + PL E++ G P
Sbjct: 539 QLSPLAPFGTNSQPGFRGPTPPSSR-----PSSTGLEDISPTPLPDSDEDEELDLGLGPR 593
Query: 320 PPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIP 379
PP P PG P P +L+ + G P + + + G+ +
Sbjct: 594 PP------PEPGPP-DPAGLLSQTAEVALDLVGDRTPT-SEKMDEGQQSSGEDMEISDDE 645
Query: 380 TPGRPLT----PQP-IPTPGRPLTPQP-IQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQG 433
P P+T P+P + TPG P + P PL PP L P P P G
Sbjct: 646 MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPP---QPG 702
Query: 434 LPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAP 471
P+P PL PP P P +PP P PP P
Sbjct: 703 FPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPP 740
Score = 54.7 bits (130), Expect = 3e-07
Identities = 76/275 (27%), Positives = 99/275 (36%), Gaps = 62/275 (22%)
Query: 175 AHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSG----------SQAPSAAHPK 224
A P G P LS S+ + S P + P L SG S P+ + P
Sbjct: 1338 ATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEP- 1396
Query: 225 RLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRE 284
S LL P R + LA+P L T LP P A P+
Sbjct: 1397 --SGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPA--------- 1445
Query: 285 SEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDP---LPPGQPQRIP-----LPGQPLQP 336
+ R Q R PL P PL P PG+P+R P L G ++P
Sbjct: 1446 -------VLRAQARAPTPLPPLLPA--PLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496
Query: 337 --------QPILTPGQPQKIPTPGQHQP--ILTPGHSQPIPTPGQPLPPQPIPTPGRPLT 386
+ +L PGQPQ P H P + + IP P PLPPQP P P
Sbjct: 1497 PAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPP----P 1552
Query: 387 PQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPG 421
P P+ +P ++P + L P + PG
Sbjct: 1553 PPPV---------EPTKLPFKELDNQWPSEAIPPG 1578
Score = 47.4 bits (111), Expect = 4e-05
Identities = 56/163 (34%), Positives = 63/163 (38%), Gaps = 28/163 (17%)
Query: 318 PLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQP 377
P PPG P PLP P P P PG P P P P P H P +PP P
Sbjct: 682 PPPPGFP---PLPPPPPPPPP--QPGFPMPPPLPPPPPPP-PPAH------PAVTVPPPP 729
Query: 378 IPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGL--- 434
+P P P P P P P P P P + + L G PMS Q+ QTQ L
Sbjct: 730 LPAP--PGVPPPPILPPLPPFP-PGLFPVMQVDMSHVLGGQWGGMPMSFQM-QTQVLSRL 785
Query: 435 -------PLPQPLLPPGQPKSAGRPLQPLPP--GPDARSISDP 468
P P + SAG LPP GP + S S P
Sbjct: 786 MTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGP 828
Score = 45.4 bits (106), Expect = 2e-04
Identities = 71/322 (22%), Positives = 116/322 (36%), Gaps = 41/322 (12%)
Query: 267 QSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDP-LPPGQP- 324
+S + PS S + + + + + + ++ +E + E + G + L PG P
Sbjct: 1122 ESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPA 1181
Query: 325 -------QRIPLPGQPLQPQP----ILTPGQPQKIPTPGQ-HQPILTPGHSQPIPTPGQP 372
+ + + + + P+ + P P + P +P PG SQ P
Sbjct: 1182 VDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSP 1241
Query: 373 LPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQ 432
PP PL+P+ P + P+P M PL L PPL RP +P SP + +
Sbjct: 1242 EPPAKEVEARPPLSPERAPEHDLEVEPEPPMM--LPLPLQPPLPPPRPPRPPSPP-PEPE 1298
Query: 433 GLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGAS 492
P +PP P P G A+S S P + PGG
Sbjct: 1299 TTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPAT--------------PGGEP 1344
Query: 493 PRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSATFSCK 552
P + ++ + +P P S S G + +++ TFS +
Sbjct: 1345 PLSGGSSG--------LSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFS-E 1395
Query: 553 PSGAASVDLRVPSPKPRALSRS 574
PSG + + P P R RS
Sbjct: 1396 PSGPLLLPV-CPLPTGRRDERS 1416
Score = 37.7 bits (86), Expect = 0.032
Identities = 62/237 (26%), Positives = 76/237 (32%), Gaps = 49/237 (20%)
Query: 257 TTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQL----RRKQQRWKEPLMPRREEKY- 311
T L P S+ ++ SR P P S+ DP + RR + ++ + R E Y
Sbjct: 273 TPLTPRLGTPFSQDSSYSSRQPTPSYLFSQ--DPAVTFKARRHESKFTDAYNRRHEHHYV 330
Query: 312 --------------PLRGTDPLPPGQPQRIP-LPGQPLQPQP------ILTPGQPQKIPT 350
RG+ LP G G P + QP TP Q P
Sbjct: 331 HNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPA 390
Query: 351 PGQHQPILTPGHSQPIPTPGQPLPPQPI-PTPGRPLTPQ--------PIPTPGRPLTPQP 401
PG P TP PP P PT + P P P P P
Sbjct: 391 PGFKSAF------SPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLA 444
Query: 402 IQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPP 458
+ PG P PPP M R T G P+P PG P P P P
Sbjct: 445 KEKPGTPPGPPPP-----DTNSMELGGRPTFGWS-PEPCDSPGTPTLESSPAGPEKP 495
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 10/102 (9%)
Query: 370 GQPLPPQPIPTPGRPLTPQPI---PTPGRPLTPQPIQMPGRPLRLPP--PLRLLRPGQPM 424
G P QP + TP P P PG P Q P PP P G
Sbjct: 365 GPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARD 424
Query: 425 SPQLRQTQGLPLPQPLLPPGQPKSAGRP-LQPLPPGPDARSI 465
S + R+ P P PL PP +P + +P P PP PD S+
Sbjct: 425 SGEFRRA---PAPPPL-PPAEPLAKEKPGTPPGPPPPDTNSM 462
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 72.8 bits (177), Expect = 9e-13
Identities = 77/246 (31%), Positives = 96/246 (39%), Gaps = 41/246 (16%)
Query: 253 PLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYP 312
P G P P + +P P P Q P K + + P P + + P
Sbjct: 47 PQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGDKSRSPRSP--PGKPQGPP 101
Query: 313 LRGTD-----PLPPGQPQRIPLPG--QPLQPQPILTPGQPQKIPTPGQ--HQPILTPGHS 363
+G + P PPG+PQ P G +P P P PG+PQ P G P PG
Sbjct: 102 PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP---PGKPQGPPPQGDKSRSPRSPPGKP 158
Query: 364 QPIPTPGQPLPPQPIPTPGRPLTPQPI--------PTPGRPLTPQPIQMPGRPLRLPPPL 415
Q P G P P P PG+P P P P PG+P P P R + PP
Sbjct: 159 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP-- 216
Query: 416 RLLRPGQPMSPQLR---QTQGLPLPQPLLPPGQPKSAG-RPLQPLPP----GPDARSISD 467
G+P P + Q QG P P P P G P G +P P PP GP A+ S
Sbjct: 217 -----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
Query: 468 PPAPRS 473
+ RS
Sbjct: 271 SQSARS 276
Score = 68.2 bits (165), Expect = 2e-11
Identities = 66/228 (28%), Positives = 88/228 (38%), Gaps = 47/228 (20%)
Query: 275 SRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTD----PLPPGQPQRIPLP 330
S+ P + + P + + P P + + P +G + P PPG+PQ P
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
Query: 331 GQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPI--------PTPG 382
G + P PG+PQ P G +QP P P PG+P P P P PG
Sbjct: 84 GDKSR-SPRSPPGKPQGPPPQGGNQP------QGPPPPPGKPQGPPPQGGNRPQGPPPPG 136
Query: 383 RPLTP--------QPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGL 434
+P P P PG+P P P Q +P PPP PG+P P QG
Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPP-QGGNQPQGPPPP-----PGKPQGPP---PQGG 187
Query: 435 PLPQPLLPPGQPK-----------SAGRPLQPLPPGPDARSISDPPAP 471
PQ PPG+P+ S P +P P P + P P
Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235
Score = 66.2 bits (160), Expect = 8e-11
Identities = 78/286 (27%), Positives = 106/286 (37%), Gaps = 59/286 (20%)
Query: 243 PDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPS--RSPEPQIRESEQRDPQLRRKQQRWK 300
P P + PP P P P +S P+ + + P + Q
Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 110
Query: 301 EPLMPRREEKYPLRGTD----PLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQP 356
P P + + P +G + P PPG+PQ P G + P PG+PQ P G +QP
Sbjct: 111 PPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR-SPRSPPGKPQGPPPQGGNQP 169
Query: 357 ILTPGHSQPIPTPGQPLPPQPI--------PTPGRPLTPQPI--------PTPGRPLTPQ 400
P P PG+P P P P PG+P P P PG+P P
Sbjct: 170 ------QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPP 223
Query: 401 PIQMPGRPLRLPPPLRLLRPGQPMSPQLR---QTQGLPLP---------------QPLLP 442
P Q +P PPP PG+P P + + QG P P P
Sbjct: 224 P-QGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277
Query: 443 PGQPK-----SAGRPLQPLPP-GPDARSISDPPAPRSRLPIRLLRG 482
PG+P+ P P PP G + + PPA + + P R +G
Sbjct: 278 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 323
Score = 62.0 bits (149), Expect = 2e-09
Identities = 66/224 (29%), Positives = 88/224 (39%), Gaps = 38/224 (16%)
Query: 243 PDPRSRLAAPPLGSTTL-----PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQ 297
P P PP G + P P + +P + P P + + PQ +K Q
Sbjct: 133 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGKKPQ 191
Query: 298 RWKEPLMPRREEKYPLRG----TDPLPPGQPQRIPLPG--QPLQPQPILTPGQPQKIPTP 351
P P + + P +G + PPG+PQ P G QP P P PG+PQ P
Sbjct: 192 G---PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP--PPGKPQGPPPQ 246
Query: 352 GQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRL 411
G ++P Q P PG+P P P G + PG+P P Q G +
Sbjct: 247 GGNKP-------QGPPPPGKPQGP---PAQGGSKSQSARSPPGKPQGPP--QQEGNNPQG 294
Query: 412 PPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQP 455
PPP P QP +P Q QG P +P GRP +P
Sbjct: 295 PPPPAGGNPQQPQAPPAGQPQG---------PPRPPQGGRPSRP 329
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 72.4 bits (176), Expect = 1e-12
Identities = 112/446 (25%), Positives = 153/446 (34%), Gaps = 84/446 (18%)
Query: 196 SRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLG 255
S+ R+ S + P + +P S P P S P P P PPL
Sbjct: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650
Query: 256 STTLPSTWTAPQ-----SRLTARPSRS---------PEPQIRESEQRDPQLRRKQQRWKE 301
S + PS +A S +T + S P P + +S+ PQ+
Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQIL-------- 702
Query: 302 PLMPRREEKYPLRGTDPLPPGQPQRIPLPGQP---LQPQPILTPGQPQ-KIPTPG----- 352
P G P PP P P PG L+P P P PQ P P
Sbjct: 703 ---------VPPNGVVPPPPPPPPP-PTPGSAMAQLKPAPC-APSLPQFSAPPPPLKIHQ 751
Query: 353 -QHQPILTPGHSQPIPTPGQPLPPQP-------IPTPGRPLTPQPIPTPGRPLTPQPIQM 404
QH + P P P PLPPQ IP P T P+ T P TP P
Sbjct: 752 VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP--- 808
Query: 405 PGRPLRLPP--PLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDA 462
P P + P P + P P P +P+P P LP Q A P PL P P
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPP-------VPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861
Query: 463 RSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMG 522
P P + L +P +P++ A K P++ P+ P
Sbjct: 862 VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP-KWQPSSIPVPSPDFPP-P 919
Query: 523 PPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPSPKPRALSRSRRYPWRRS 582
PP++S F + +P T S P + S P K ++
Sbjct: 920 PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS-----PGKKT-----------SKT 963
Query: 583 ADRCAKKPWRSGPRSAQRRNAVSSST 608
+ KKP P + QR +++ SS+
Sbjct: 964 SSPGGKKP----PPTPQRNSSIKSSS 985
Score = 60.5 bits (145), Expect = 5e-09
Identities = 145/649 (22%), Positives = 217/649 (33%), Gaps = 149/649 (22%)
Query: 5 PVDPQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSSLDSPVG 64
P P P P S +G PM ++ +RL + A + SG + PV
Sbjct: 639 PPPPPPPPPPLPSQSAPSAGSAAPM-----FVKYSTITRLQN-ASQHSGALFKPPTPPVM 692
Query: 65 SMQALRPSA---QHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQT 121
Q+++P + P P P +A+ Q K P + SLP+ +A +
Sbjct: 693 QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA-PSLPQFSAPPPPLKIHQ 751
Query: 122 LLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFP 181
+ QV +P P P P P +A PL + P
Sbjct: 752 VQHITQVAPPTPPPPPPIPAP------LPPQAPPKPLVTI-------------------P 786
Query: 182 ELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWR 241
+ T A Q+ P + +PP + P+ P++ P
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA---FPASYIPP----------------- 826
Query: 242 SPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKE 301
+PP +P Q A+P SP + +++ ++
Sbjct: 827 ---------SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSV------VKQIASQFPP 871
Query: 302 PLMPRREEKYPLRGTDPLPPG-QPQRIP-LPGQPL-QPQPILTPGQPQKIPTPGQHQPIL 358
P P E PL+ P+P PQ P + +P QP I P P P P + +
Sbjct: 872 PPTPPAMESQPLK---PVPANVAPQSPPAVKAKPKWQPSSIPVPS-PDFPPPPPESSLVF 927
Query: 359 TPGHSQPIPTPGQPLPPQPIPTPGRPLTP-------------QPIPTPGRPLT------- 398
P P+P P P PP PTP + +P +P PTP R +
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Query: 399 --PQPIQMPGRPL--RLPPPLR--------LLRPGQPMSPQLRQTQGLPLP----QPLLP 442
P+P + L + PP L P P P G+ LP Q +
Sbjct: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047
Query: 443 PGQPKSAGRPLQPLPPGPDARSISD--PPAPRSRLPIRLLRGLLARLPGGASPRAAA--- 497
P +GR + P S SD PP P + LP+ + + A G SP+ A
Sbjct: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIE-IPAVFSGNTSPKVAVVNP 1106
Query: 498 ------------AAACTTMKGWPAATMTPAETS--PTMG--------PPDASAGFSIGEI 535
A T K + +T AE S PTM P +S G +
Sbjct: 1107 QPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFL 1166
Query: 536 A----AAESPSATYSATFSCKPSGAASV----DLRVPSPKPRALSRSRR 576
A + S T + S + S A D+ +P P P LS ++
Sbjct: 1167 ADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 71.6 bits (174), Expect = 2e-12
Identities = 94/350 (26%), Positives = 131/350 (37%), Gaps = 72/350 (20%)
Query: 179 GFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAP 238
G P+L + S SRP + LPP R S + P R R+ P
Sbjct: 107 GMPKLRSTANRDNDSGGSRPPL----LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPP 162
Query: 239 GW---RSPDPRSRLAA------PPLGSTTLPSTWTAPQSR-----------LTARPSRSP 278
R P PR + + PP+ ST P ++P +R + P+ P
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQ-SSPHNRGSPPVPGGPRQPSPGPTPPP 221
Query: 279 EPQIRESEQRDPQLRRKQQRWKEPLMPRRE-EKYPLRGTDPLPPGQPQRIPLPGQPLQPQ 337
P R + +R+ P R P R D PP P P+ +P +
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP--PVGNRPSIHR 279
Query: 338 PILTPGQPQ--KIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIP--TPGRPLTPQ----- 388
+ P PQ K P P +P + P P P +P PP P+P + G TP+
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQRN 338
Query: 389 --------PIPTPGR--PLTPQPIQMPGRPLR--------LPPPLRLLRPGQ-----PMS 425
P+P+PGR PL P P + P P+R LPPP + R G P +
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
Query: 426 PQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRL 475
PQL G+ P+S RP PLPP + PP P + +
Sbjct: 399 PQLPSRSGVD---------SPRSGPRP--PLPPDRPSAGAPPPPPPSTSI 437
Score = 43.1 bits (100), Expect = 8e-04
Identities = 58/232 (25%), Positives = 80/232 (34%), Gaps = 26/232 (11%)
Query: 243 PDPRSRLAAPPLGSTTLPS--TWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK 300
P P + PP+ ST PS + P +RP P P P+L ++
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342
Query: 301 EPLMPRREEKYPLRG-TDPLPPGQPQRIPLPGQ-------PLQPQPILTPGQPQKIPTPG 352
P P G + PLPP +R P P + PL P P ++ P
Sbjct: 343 SSTPP-----LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 353 QHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLP 412
Q G P P PLPP P+ G P P P + P +
Sbjct: 398 TPQLPSRSGVDSPRSGPRPPLPPDR-PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456
Query: 413 PPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAG----RPLQPLPPGP 460
P+ L P + P ++ T+ P L + +S R PLPP P
Sbjct: 457 HPISDLPPPE---PYVQTTKSYP---SKLARNESRSGSNRRERGAPPLPPIP 502
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 71.6 bits (174), Expect = 2e-12
Identities = 94/350 (26%), Positives = 131/350 (37%), Gaps = 72/350 (20%)
Query: 179 GFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAP 238
G P+L + S SRP + LPP R S + P R R+ P
Sbjct: 107 GMPKLRSTANRDNDSGGSRPPL----LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPP 162
Query: 239 GW---RSPDPRSRLAA------PPLGSTTLPSTWTAPQSR-----------LTARPSRSP 278
R P PR + + PP+ ST P ++P +R + P+ P
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQ-SSPHNRGSPPVPGGPRQPSPGPTPPP 221
Query: 279 EPQIRESEQRDPQLRRKQQRWKEPLMPRRE-EKYPLRGTDPLPPGQPQRIPLPGQPLQPQ 337
P R + +R+ P R P R D PP P P+ +P +
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP--PVGNRPSIHR 279
Query: 338 PILTPGQPQ--KIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIP--TPGRPLTPQ----- 388
+ P PQ K P P +P + P P P +P PP P+P + G TP+
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQRN 338
Query: 389 --------PIPTPGR--PLTPQPIQMPGRPLR--------LPPPLRLLRPGQ-----PMS 425
P+P+PGR PL P P + P P+R LPPP + R G P +
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
Query: 426 PQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRL 475
PQL G+ P+S RP PLPP + PP P + +
Sbjct: 399 PQLPSRSGVD---------SPRSGPRP--PLPPDRPSAGAPPPPPPSTSI 437
Score = 43.1 bits (100), Expect = 8e-04
Identities = 58/232 (25%), Positives = 80/232 (34%), Gaps = 26/232 (11%)
Query: 243 PDPRSRLAAPPLGSTTLPS--TWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK 300
P P + PP+ ST PS + P +RP P P P+L ++
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342
Query: 301 EPLMPRREEKYPLRG-TDPLPPGQPQRIPLPGQ-------PLQPQPILTPGQPQKIPTPG 352
P P G + PLPP +R P P + PL P P ++ P
Sbjct: 343 SSTPP-----LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 353 QHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLP 412
Q G P P PLPP P+ G P P P + P +
Sbjct: 398 TPQLPSRSGVDSPRSGPRPPLPPDR-PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456
Query: 413 PPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAG----RPLQPLPPGP 460
P+ L P + P ++ T+ P L + +S R PLPP P
Sbjct: 457 HPISDLPPPE---PYVQTTKSYP---SKLARNESRSGSNRRERGAPPLPPIP 502
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 71.2 bits (173), Expect = 3e-12
Identities = 93/327 (28%), Positives = 118/327 (36%), Gaps = 51/327 (15%)
Query: 175 AHPRGFPELSHKSTAAASSRQSRPRVRSASLPP---RTRLPSGSQAPSAAHPKRLSDLLL 231
A P P ST +S R++ P+ RSA L TRL +Q + P+ S
Sbjct: 20 APPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIES---- 75
Query: 232 TSRAAAPGWRSPDPRSRLAAPPLGSTT---LPSTWTAPQSRLTARP------SRSPEPQI 282
+ G S + R P LG P A Q + SR+P P++
Sbjct: 76 SKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRL 135
Query: 283 RESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTP 342
P + P PR G P P P P P P P
Sbjct: 136 PNKTISGPLI--------PPASPRLGNTSEAHGAARTAP------PRPNVPAPPPPTPPP 181
Query: 343 GQPQKIPTPGQHQPILTPGHSQP-------IPTPGQPLP-PQPIPTPGRPLTPQPIPTPG 394
P P PI TP S P +P P+P P P P P TP P+P P
Sbjct: 182 PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP-PA 240
Query: 395 RPLTPQPIQMPGRPLRL---PPPLRLLRP-------GQPMSPQLRQTQGLPLPQPLLPPG 444
L+ + ++ PL L PPPL LL P +P SP + Q P P P LPP
Sbjct: 241 SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASP-AQDAQEPPAPPPPLPP- 298
Query: 445 QPKSAGRPLQPLPPGPDARSISDPPAP 471
+ R P PP P S S+ P P
Sbjct: 299 YASCSPRASLPAPPLPGVNSSSETPPP 325
Score = 70.5 bits (171), Expect = 4e-12
Identities = 98/379 (25%), Positives = 126/379 (33%), Gaps = 55/379 (14%)
Query: 133 PELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAAS 192
P P S S L+R P+ +AL L + + + K T + R P++ S
Sbjct: 26 PSAPPVSTDTSSLRRADPKGRSAL-LADIQQGTRLRKV--TQINDRSAPQIE-SSKGTNK 81
Query: 193 SRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPR--SRLA 250
R AS PP P P D+ PG R+P PR ++
Sbjct: 82 EGGGSANTRGASTPPTLGDLFAGGFP-VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTI 140
Query: 251 APPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEK 310
+ PL P ++ AR + P P + P PL P
Sbjct: 141 SGPLIPPASPRLGNTSEAHGAARTA-PPRPNVPAPPPPTPPPP------PPPLPPPLPSS 193
Query: 311 YPLRGTDPLPPGQPQR----IPLPGQPLQPQPILTPGQPQKIPTPGQH-------QPILT 359
P++ PPG + + P P P P P P P P +P L
Sbjct: 194 SPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA 253
Query: 360 PGHSQPIPTPGQPLPP-----------------QPIPTPGRPLTPQPIPTPGRPLTPQPI 402
P H PIP P LPP Q P P PL P +P L P+
Sbjct: 254 PLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL 313
Query: 403 QMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPG-----QPKSAGRPLQPLP 457
PPPL P PQ Q LP P PPG Q K GR
Sbjct: 314 PGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPP--APPGSQPFLQKKRHGR------ 365
Query: 458 PGPDARSISDPPAPRSRLP 476
PG ++ PPAP +R P
Sbjct: 366 PGAGGGKLNPPPAPPARSP 384
Score = 40.4 bits (93), Expect = 0.005
Identities = 76/308 (24%), Positives = 101/308 (32%), Gaps = 45/308 (14%)
Query: 243 PDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLR---RKQQRW 299
P P PPLG+ P P S T+ R+ +P+ R + D Q RK +
Sbjct: 7 PPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRA-DPKGRSALLADIQQGTRLRKVTQI 65
Query: 300 KEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQ------PILTPGQPQKIP--TP 351
+ P+ E +GT+ G P P+L P + +
Sbjct: 66 NDRSAPQIESS---KGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKT 122
Query: 352 GQHQPILTPGHSQPIPTPGQPLPPQPIPTPGR------------PLTPQPIPTPGRPLTP 399
GQ P P T PL P P G P P P P P P
Sbjct: 123 GQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP 182
Query: 400 QPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQG-LPLPQPLLPPGQPKSAGRPLQPLPP 458
P P P P L+ P P+ T+G LP+ P +P P P PP
Sbjct: 183 PPPLPPPLPSSSPIKTPLVSPPGPL------TKGNLPVVAPPVPCAPPPPPPPPPPTPPP 236
Query: 459 GPDARSISDPPAPRSRLPIRL--LRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAE 516
P A +SD P+ L + L LP P +K PA+ A+
Sbjct: 237 LPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP---------GLKAEPASPAQDAQ 287
Query: 517 TSPTMGPP 524
P PP
Sbjct: 288 EPPAPPPP 295
Score = 32.7 bits (73), Expect = 1.0
Identities = 53/204 (25%), Positives = 67/204 (32%), Gaps = 64/204 (31%)
Query: 365 PIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPP---------- 414
P+P P PP P+P P PL P P P P P+ LR P
Sbjct: 2 PVPPP----PPPPLPPPPPPLGAPPPPPPSAP----PVSTDTSSLRRADPKGRSALLADI 53
Query: 415 ------LRLLRPGQPMSPQLR-------------QTQGLPLPQP-----------LLPPG 444
++ + +PQ+ T+G P L P G
Sbjct: 54 QQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAG 113
Query: 445 QPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPR----AAAAAA 500
Q AG GP +R AP RLP + + G L +P ASPR + A A
Sbjct: 114 QRDVAG---GKTGQGPGSR------APSPRLPNKTISGPL--IP-PASPRLGNTSEAHGA 161
Query: 501 CTTMKGWPAATMTPAETSPTMGPP 524
T P P T P PP
Sbjct: 162 ARTAPPRPNVPAPPPPTPPPPPPP 185
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 70.9 bits (172), Expect = 3e-12
Identities = 77/279 (27%), Positives = 105/279 (37%), Gaps = 42/279 (15%)
Query: 313 LRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPT-PGQ 371
L LPP + P P QP + GQPQ P P + S P+P PG
Sbjct: 246 LTAVSQLPPSEKMSQPTPAQPQS----FSVGQPQPPPPPVGGAVAQS---SAPLPPFPGA 298
Query: 372 PLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPM-SPQLRQ 430
PQP+ +P PQ G+ L P + + + LPP +PG + +P +Q
Sbjct: 299 ATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPP-----QPGPAVGAPAAQQ 353
Query: 431 TQGLPLPQPLLPPG-----QPKSAGRPLQ--------PLPPGPDARSISDPPAPRSRLPI 477
Q PQP +PPG QP LQ P P P + + PA + LP+
Sbjct: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413
Query: 478 ---RLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGF---- 530
+ + A+L G +S + A A T PA A PT PP G
Sbjct: 414 GTGQNASSVGAQLMGASSQPSEAMAPRT----GPAQGGQVAPCQPTGVPPATVGGVVQPC 469
Query: 531 ----SIGEIAAAESPSATYSATFSCKPSGAASVDLRVPS 565
G+ + P S S P G +V VP+
Sbjct: 470 LGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPN 508
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 70.5 bits (171), Expect = 4e-12
Identities = 63/199 (31%), Positives = 78/199 (39%), Gaps = 41/199 (20%)
Query: 318 PLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQP 377
P PPG+PQ P G P PG+P+ P G +Q P P PG+P P P
Sbjct: 51 PPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQ------SQGPPPHPGKPERPPP 104
Query: 378 ---------IPTPGRPLTP---------QPIPTPGRPLTPQ---------PIQMPGRPLR 410
P PG+P P +P P PG+P P P PG+P
Sbjct: 105 QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEG 164
Query: 411 LPP----PLRLLR--PGQPMS-PQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPGPDAR 463
PP R R PG+P PQ + P P P G P + G P QP P P +
Sbjct: 165 PPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAP-PAGK 223
Query: 464 SISDPPAPRSRLPIRLLRG 482
PP P+ P R +G
Sbjct: 224 PQGPPPPPQGGRPPRPAQG 242
Score = 67.8 bits (164), Expect = 3e-11
Identities = 67/228 (29%), Positives = 90/228 (39%), Gaps = 43/228 (18%)
Query: 241 RSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK 300
R P P + PP PQ S+ P P + E R PQ + Q
Sbjct: 49 RPPPPPGKPQGPP------------PQG---GNQSQGPPPPPGKPEGRPPQGGNQSQG-- 91
Query: 301 EPLMPRREEKYPLRGTD-----PLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQ 355
P P + E+ P +G + P PPG+P+R P G +P PG+P++ P G +Q
Sbjct: 92 PPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQ 151
Query: 356 PILTPGHSQPIPTPGQPLPPQPIP---------TPGRPLTPQPIPTPGRPLTPQPIQMPG 406
P P PG+P P P PG+P P P +P P P PG
Sbjct: 152 S------QGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGP-PQQEGNKPQGPPP---PG 201
Query: 407 RPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQ 454
+P PP P QP +P + QG P P P +P +P Q
Sbjct: 202 KPQGPPPAGG--NPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPPQ 247
Score = 50.1 bits (118), Expect = 6e-06
Identities = 47/145 (32%), Positives = 63/145 (43%), Gaps = 29/145 (20%)
Query: 340 LTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTP 399
L G+P+ G +QP +P P PG+P P P G + P P PG+P
Sbjct: 31 LISGKPEGRRPQGGNQP------QRPPPPPGKPQGPPP---QGGNQSQGPPPPPGKPEGR 81
Query: 400 QPIQMPGRPLRLPPPLRLLRPGQPMSPQLR---QTQGLPLP--QPLLPPGQ--------P 446
P G + PPP PG+P P + Q+QG P P +P PP Q P
Sbjct: 82 PP--QGGNQSQGPPP----HPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP 135
Query: 447 KSAGRPLQPLPPGPDARSISDPPAP 471
G+P +P P G + +S PP P
Sbjct: 136 PPPGKPERPPPQGGN-QSQGPPPHP 159
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 70.1 bits (170), Expect = 6e-12
Identities = 117/457 (25%), Positives = 157/457 (34%), Gaps = 93/457 (20%)
Query: 206 PPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTA 265
P RT PS + + P L L A+PG P R+ T+L S +
Sbjct: 574 PERTLSPSSGYSSQSGTPT-LPPKGLAGPPASPGKAQPPKPERV-------TSLRSPGAS 625
Query: 266 PQSRLTARPSRSPEPQIRESEQRDPQ-LRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQP 324
S LT+ S S +P S++ PQ L R+ P P+ + PP
Sbjct: 626 VSSSLTSLCSSSSDPA--PSDRSGPQILTPLGDRFVIPPHPKVPAPFS-------PPPSK 676
Query: 325 QRIPLPGQPLQPQPILTPG-------QPQKIPTPG------QHQPILTPGHSQPIPTPGQ 371
R P P P P + PG PQ PTP Q P+++ S P P+P
Sbjct: 677 PRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPP-PSPPP 735
Query: 372 PLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQT 431
P P PT +P P+ +P+Q P P PPP P P L
Sbjct: 736 SYHPPPPPTK-KPEVVVEAPSASE-TAEEPLQDPNWP---PPP-----PPAPEEQDLSMA 785
Query: 432 QGLP---------LPQPLLPPGQPKSAGRP---------LQPLPPGPDARSISDPPAPRS 473
P P+P P G P+ P LQ PPG S PPAP +
Sbjct: 786 DFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPG----SPDPPPAPPA 841
Query: 474 RLPIRLLRGLLARLP---------GGASPRAAAAAACTTMK----------GWPAATMTP 514
P G +A+LP GG PR A T G P TP
Sbjct: 842 PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901
Query: 515 AETSPTMGPPDASAGFSIGEIAAAESPSATYSATF---SCKPSGAASVDLRVPSPKPRAL 571
A P+ S G + +PS+ A +C + + + P+ P A
Sbjct: 902 A-LGPSAPQKPLRRALS-GRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE 959
Query: 572 SRSRRYPWRRSADRCAKKPWRSGPRSAQRRNAVSSST 608
R + P ++ +K G R Q VS T
Sbjct: 960 PRPPQSPASTASFIFSK-----GSRKLQLERPVSPET 991
Score = 52.8 bits (125), Expect = 1e-06
Identities = 111/483 (22%), Positives = 159/483 (32%), Gaps = 75/483 (15%)
Query: 139 SPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPEL----SHKSTAAASSR 194
S P+ ++ L + + P R H S T +H + + S S+ S
Sbjct: 384 SASPASVRSLGRFSSVSSPQPRSRHPS---SSSDTWSHSQSSDTIVSDGSTLSSKGGSEG 440
Query: 195 QSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPR--SRLAAP 252
Q S S+ P + SG +PS SD L + RS R R P
Sbjct: 441 QPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP 500
Query: 253 PLGSTTLPSTWTAPQS---RLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREE 309
P + +L A L +P R +PQ+ R P + P P
Sbjct: 501 PRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQL----PRPPTTGGSEGAGAAPCPPNPAN 556
Query: 310 KYPLRGTDP----LPPGQPQRIPLP--------GQPLQPQ-----PILTPGQPQKIPTPG 352
+ + G P PP P+R P G P P P +PG+ Q P P
Sbjct: 557 SW-VPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP-PKPE 614
Query: 353 QHQPILTPG-----------HSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQP 401
+ + +PG S P P PQ + G P P P +P P
Sbjct: 615 RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP 674
Query: 402 IQMPGRPLRLPPPLR--LLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPG 459
P P P L + PG P+S Q P PQ L P Q Q PP
Sbjct: 675 -SKPRSPNPAAPALAAPAVVPG-PVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS 732
Query: 460 PDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGW-PAATMTPAETS 518
P PP P ++ P ++ A + A W P P E
Sbjct: 733 PPPS--YHPPPPPTKKPEVVVE---------APSASETAEEPLQDPNWPPPPPPAPEEQD 781
Query: 519 PTMG--PPDASAGFSIG-----------EIAAAESPSATYSATFSCKPSGAASVDLRVPS 565
+M PP A FS+ E+ ++ + S++ + +P G+ P+
Sbjct: 782 LSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPA 841
Query: 566 PKP 568
P P
Sbjct: 842 PAP 844
Score = 35.8 bits (81), Expect = 0.12
Identities = 61/256 (23%), Positives = 90/256 (35%), Gaps = 24/256 (9%)
Query: 175 AHPRGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSR 234
A P G PEL S AA+SS + +++ P P + AP+++ P ++ L
Sbjct: 803 AGPSGSPELV-SSPAASSSSATALQIQPPGSPDPPPAPP-APAPASSAPGHVAKLPQKEP 860
Query: 235 AAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRR 294
P PR + AP PS + R P +P P + S + P R
Sbjct: 861 VGCSKGGGP-PREDVGAP----LVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRA 915
Query: 295 KQQRWKEPLMPR-------REEKYPLRGTDPL----PPGQPQRIPLPGQ-PLQPQPILTP 342
R P R + L ++ L P G P+ P P Q P +
Sbjct: 916 LSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFS 975
Query: 343 GQPQKI----PTPGQHQPILTPGHSQPIPTPGQPLPPQ-PIPTPGRPLTPQPIPTPGRPL 397
+K+ P + Q L + + + PPQ P +P P P+ G P
Sbjct: 976 KGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPP 1035
Query: 398 TPQPIQMPGRPLRLPP 413
P PL PP
Sbjct: 1036 PASPSYPRAEPLTAPP 1051
Score = 35.4 bits (80), Expect = 0.16
Identities = 86/411 (20%), Positives = 131/411 (31%), Gaps = 72/411 (17%)
Query: 8 PQRSPDPTFRSSTRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSS----LDSPV 63
P + D + +S L P++ + + + Q P P++ +++P
Sbjct: 696 PVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS 755
Query: 64 GSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRS---- 119
S A P +W P P P++ LS+ P FS S
Sbjct: 756 ASETAEEPLQDPNWPPPPPPAPEEQ------------DLSMADFPPPEEAFFSVASPEPA 803
Query: 120 ------------QTLLQEAQVLQ----GSPELLPRSPKPSGLQRLAPEEATALPLRRLCH 163
A LQ GSP+ P P P+ AP LP +
Sbjct: 804 GPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASS-APGHVAKLPQKEPVG 862
Query: 164 LSL----MEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRV-RSASLPPRTRLPSGSQAP 218
S +D+G ++ + A P + SA P R SG +P
Sbjct: 863 CSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASP 922
Query: 219 SAAHPKRLS---DLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPS 275
A L L S AA+ G S P PP P + + S + ++ S
Sbjct: 923 VPAPSSGLHAAVRLKACSLAASEGLSSAQPN----GPPEAEPRPPQSPASTASFIFSKGS 978
Query: 276 R--------SPEPQ-------IRE----SEQRDPQLRRKQQRWKEPLMPRREEKYPLRGT 316
R SPE Q + E SEQR PQ +K + P+ + P
Sbjct: 979 RKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVP---- 1034
Query: 317 DPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIP 367
P P P+ PL P P +++ G ++ P +P
Sbjct: 1035 PPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLP 1085
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 69.7 bits (169), Expect = 8e-12
Identities = 96/405 (23%), Positives = 135/405 (33%), Gaps = 47/405 (11%)
Query: 186 KSTAAASSRQSRPRV-RSASLPPRTRLPSGSQAPSAAHPKRLSDLL------LTSRAAAP 238
K A ++++ P +SA P+ P+ + P+ PK + T + AP
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 335
Query: 239 GWRSPDPRS-RLAAPPLGSTTLPST--WTAPQSRLTARPSRSPEPQIRESEQRDPQLRRK 295
+ P P + + AP P+T AP + P+ + EP ++ P +
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Query: 296 QQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQ 355
+ P + P +P P + P P P +P P TP +P PT +
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTTPKEPAPT-TPKKPA--PTTPKEP 450
Query: 356 PILTPGHSQPIPT--PGQPLPPQPIPTPGR---PLTPQPI-PTPGRPLTPQPIQMPGRPL 409
TP P T P P +P PT + P TP+ + PT L P + P
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--- 507
Query: 410 RLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAGRPLQPLPPGPDARSI 465
P L P P P + P P P P PK P P P P
Sbjct: 508 --PTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKE 561
Query: 466 SDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP----AATMTPAETSPTM 521
P P+ P P G +P A TT K A T T TS T
Sbjct: 562 PAPTTPKETAPTT---------PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 612
Query: 522 GPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPSP 566
P + E T P G A L+ P+P
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 657
Score = 67.4 bits (163), Expect = 4e-11
Identities = 113/484 (23%), Positives = 168/484 (34%), Gaps = 72/484 (14%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQS 196
P +P+PS + T+L + + + E TT + + + K+T+A + QS
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKET---TTTNKQTSTDGKEKTTSAKET-QS 178
Query: 197 RPRVRSASLPPRTRL--------PSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSR 248
+ + L P +++ + ++ P+ PK + A+ + P P +
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP-KEPTPTTI 237
Query: 249 LAAPPLGSTTLPSTW-TAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRR 307
+AP P+T +AP + P+ + EP ++ P KEP P
Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT------KEPA-PTT 290
Query: 308 EEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQ----KIPTPGQHQPILTPGHS 363
+ P +P P P++ P P P +P P TP +P K P P +P T
Sbjct: 291 TKSAPTTPKEPAPT-TPKK-PAPTTPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTP-K 346
Query: 364 QPIPT-PGQPLPPQPI-PTPGRPLTPQPI----PTPGRPLTPQPIQMPGRPLRLPPPLRL 417
+P PT P +P P P P P P P P P+P P P P P P
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 418 LRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAG-------RPLQPLPPGPDARSIS 466
P +P+ P P P P PK P P P P
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466
Query: 467 DPPAPRSRLPI-------RLLRGLLARLPGGASPRAAAAAACTTMKGWPAAT------MT 513
P P+ P + L P +P A TT + T T
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 526
Query: 514 PAETSPTMGPPDASAGFSIGEIAAA-----------ESPSATYSATFSCKPSGAASVDLR 562
P E +PT P A+A + E A E T T P G A L+
Sbjct: 527 PEEPAPT--TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584
Query: 563 VPSP 566
P+P
Sbjct: 585 EPAP 588
Score = 53.5 bits (127), Expect = 6e-07
Identities = 95/432 (21%), Positives = 143/432 (33%), Gaps = 57/432 (13%)
Query: 108 PREAAVNFSYRSQTLLQE-AQVLQGSPELLPRSPKPSGLQRLAP----EEATALPLRRLC 162
P+E A + + T +E A S P+ P P+ + AP E A P
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP----- 439
Query: 163 HLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLP--PRTRLPSGSQAPSA 220
+K TT P+ + K A ++++ P P P+ P+ + +
Sbjct: 440 -----KKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492
Query: 221 AHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEP 280
P++L+ T AP P P T AP + A P+ EP
Sbjct: 493 TTPEKLAPT--TPEKPAP----TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546
Query: 281 QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPIL 340
++ P ++ P P+ +GT P +P P P +P P
Sbjct: 547 APTTPKEPAPTTPKEPA----PTTPKETAPTTPKGTAPTTLKEPA----PTTPKKPAPKE 598
Query: 341 TPGQPQKIPT------PGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPG 394
K PT P P T + P P P P P G T P P
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658
Query: 395 RPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQ 454
P P P ++ + P +P P +P ++T +P P PK P
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPA-PTTP--KETAPTTPKEP--APTTPKKPA-PTT 712
Query: 455 PLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP-----A 509
P P P +S P + I + P ++P +A ++ P
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIH-------KSPDESTPELSAEPTPKALENSPKEPGVP 765
Query: 510 ATMTPAETSPTM 521
T TPA T P M
Sbjct: 766 TTKTPAATKPEM 777
Score = 33.9 bits (76), Expect = 0.46
Identities = 68/338 (20%), Positives = 115/338 (34%), Gaps = 56/338 (16%)
Query: 132 SPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAA 191
+P+ L SPK G+ AT + E+DL TT K TA
Sbjct: 751 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 810
Query: 192 SSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAA 251
+ + + ++ + + T++ S + + P +++ L T+ A P+
Sbjct: 811 TEKTTESKITATT----TQVTSTTTQDTT--PFKITTLKTTTLA---------PKVTTTK 855
Query: 252 PPLGSTTL---PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRRE 308
+ +T + P P+ R T + +P+PQ + P +K + P+
Sbjct: 856 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 915
Query: 309 EKYPLRGTDPLPPGQP---------QRIPLPGQPLQPQPILTPGQPQKIPTPGQH----Q 355
P + T +P P Q P Q P L P+ G
Sbjct: 916 PT-PRKMTSTMPELNPTSRIAEAMLQTTTRPNQ--TPNSKLVEVNPKSEDAGGAEGETPH 972
Query: 356 PILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPL 415
+L P P TP P+ +P G + P L+ + G+P+ L
Sbjct: 973 MLLRPHVFMPEVTPDMDYLPR-VPNQGIIINPM--------LSDETNICNGKPVDGLTTL 1023
Query: 416 R-------------LLRPGQPMSPQLRQTQGLPLPQPL 440
R +L P P SP R T+ +P P+
Sbjct: 1024 RNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPI 1061
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 69.7 bits (169), Expect = 8e-12
Identities = 96/405 (23%), Positives = 135/405 (33%), Gaps = 47/405 (11%)
Query: 186 KSTAAASSRQSRPRV-RSASLPPRTRLPSGSQAPSAAHPKRLSDLL------LTSRAAAP 238
K A ++++ P +SA P+ P+ + P+ PK + T + AP
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 376
Query: 239 GWRSPDPRS-RLAAPPLGSTTLPST--WTAPQSRLTARPSRSPEPQIRESEQRDPQLRRK 295
+ P P + + AP P+T AP + P+ + EP ++ P +
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436
Query: 296 QQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQ 355
+ P + P +P P + P P P +P P TP +P PT +
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTTPKEPAPT-TPKKPA--PTTPKEP 491
Query: 356 PILTPGHSQPIPT--PGQPLPPQPIPTPGR---PLTPQPI-PTPGRPLTPQPIQMPGRPL 409
TP P T P P +P PT + P TP+ + PT L P + P
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--- 548
Query: 410 RLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAGRPLQPLPPGPDARSI 465
P L P P P + P P P P PK P P P P
Sbjct: 549 --PTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKE 602
Query: 466 SDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP----AATMTPAETSPTM 521
P P+ P P G +P A TT K A T T TS T
Sbjct: 603 PAPTTPKETAPTT---------PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 653
Query: 522 GPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPSP 566
P + E T P G A L+ P+P
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 698
Score = 67.4 bits (163), Expect = 4e-11
Identities = 113/484 (23%), Positives = 168/484 (34%), Gaps = 72/484 (14%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQS 196
P +P+PS + T+L + + + E TT + + + K+T+A + QS
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKET---TTTNKQTSTDGKEKTTSAKET-QS 219
Query: 197 RPRVRSASLPPRTRL--------PSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSR 248
+ + L P +++ + ++ P+ PK + A+ + P P +
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP-KEPTPTTI 278
Query: 249 LAAPPLGSTTLPSTW-TAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRR 307
+AP P+T +AP + P+ + EP ++ P KEP P
Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT------KEPA-PTT 331
Query: 308 EEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQ----KIPTPGQHQPILTPGHS 363
+ P +P P P++ P P P +P P TP +P K P P +P T
Sbjct: 332 TKSAPTTPKEPAPT-TPKK-PAPTTPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTP-K 387
Query: 364 QPIPT-PGQPLPPQPI-PTPGRPLTPQPI----PTPGRPLTPQPIQMPGRPLRLPPPLRL 417
+P PT P +P P P P P P P P P+P P P P P P
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 418 LRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAG-------RPLQPLPPGPDARSIS 466
P +P+ P P P P PK P P P P
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507
Query: 467 DPPAPRSRLPI-------RLLRGLLARLPGGASPRAAAAAACTTMKGWPAAT------MT 513
P P+ P + L P +P A TT + T T
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 567
Query: 514 PAETSPTMGPPDASAGFSIGEIAAA-----------ESPSATYSATFSCKPSGAASVDLR 562
P E +PT P A+A + E A E T T P G A L+
Sbjct: 568 PEEPAPT--TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625
Query: 563 VPSP 566
P+P
Sbjct: 626 EPAP 629
Score = 53.5 bits (127), Expect = 6e-07
Identities = 95/432 (21%), Positives = 143/432 (33%), Gaps = 57/432 (13%)
Query: 108 PREAAVNFSYRSQTLLQE-AQVLQGSPELLPRSPKPSGLQRLAP----EEATALPLRRLC 162
P+E A + + T +E A S P+ P P+ + AP E A P
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP----- 480
Query: 163 HLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLP--PRTRLPSGSQAPSA 220
+K TT P+ + K A ++++ P P P+ P+ + +
Sbjct: 481 -----KKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 533
Query: 221 AHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEP 280
P++L+ T AP P P T AP + A P+ EP
Sbjct: 534 TTPEKLAPT--TPEKPAP----TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587
Query: 281 QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPIL 340
++ P ++ P P+ +GT P +P P P +P P
Sbjct: 588 APTTPKEPAPTTPKEPA----PTTPKETAPTTPKGTAPTTLKEPA----PTTPKKPAPKE 639
Query: 341 TPGQPQKIPT------PGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPG 394
K PT P P T + P P P P P G T P P
Sbjct: 640 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699
Query: 395 RPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQ 454
P P P ++ + P +P P +P ++T +P P PK P
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPA-PTTP--KETAPTTPKEP--APTTPKKPA-PTT 753
Query: 455 PLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP-----A 509
P P P +S P + I + P ++P +A ++ P
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIH-------KSPDESTPELSAEPTPKALENSPKEPGVP 806
Query: 510 ATMTPAETSPTM 521
T TPA T P M
Sbjct: 807 TTKTPAATKPEM 818
Score = 33.9 bits (76), Expect = 0.46
Identities = 68/338 (20%), Positives = 115/338 (34%), Gaps = 56/338 (16%)
Query: 132 SPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAA 191
+P+ L SPK G+ AT + E+DL TT K TA
Sbjct: 792 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 851
Query: 192 SSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAA 251
+ + + ++ + + T++ S + + P +++ L T+ A P+
Sbjct: 852 TEKTTESKITATT----TQVTSTTTQDTT--PFKITTLKTTTLA---------PKVTTTK 896
Query: 252 PPLGSTTL---PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRRE 308
+ +T + P P+ R T + +P+PQ + P +K + P+
Sbjct: 897 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 956
Query: 309 EKYPLRGTDPLPPGQP---------QRIPLPGQPLQPQPILTPGQPQKIPTPGQH----Q 355
P + T +P P Q P Q P L P+ G
Sbjct: 957 PT-PRKMTSTMPELNPTSRIAEAMLQTTTRPNQ--TPNSKLVEVNPKSEDAGGAEGETPH 1013
Query: 356 PILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPL 415
+L P P TP P+ +P G + P L+ + G+P+ L
Sbjct: 1014 MLLRPHVFMPEVTPDMDYLPR-VPNQGIIINPM--------LSDETNICNGKPVDGLTTL 1064
Query: 416 R-------------LLRPGQPMSPQLRQTQGLPLPQPL 440
R +L P P SP R T+ +P P+
Sbjct: 1065 RNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPI 1102
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 69.7 bits (169), Expect = 8e-12
Identities = 96/405 (23%), Positives = 135/405 (33%), Gaps = 47/405 (11%)
Query: 186 KSTAAASSRQSRPRV-RSASLPPRTRLPSGSQAPSAAHPKRLSDLL------LTSRAAAP 238
K A ++++ P +SA P+ P+ + P+ PK + T + AP
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 428
Query: 239 GWRSPDPRS-RLAAPPLGSTTLPST--WTAPQSRLTARPSRSPEPQIRESEQRDPQLRRK 295
+ P P + + AP P+T AP + P+ + EP ++ P +
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488
Query: 296 QQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQ 355
+ P + P +P P + P P P +P P TP +P PT +
Sbjct: 489 APTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTTPKEPAPT-TPKKPA--PTTPKEP 543
Query: 356 PILTPGHSQPIPT--PGQPLPPQPIPTPGR---PLTPQPI-PTPGRPLTPQPIQMPGRPL 409
TP P T P P +P PT + P TP+ + PT L P + P
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--- 600
Query: 410 RLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAGRPLQPLPPGPDARSI 465
P L P P P + P P P P PK P P P P
Sbjct: 601 --PTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKE 654
Query: 466 SDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP----AATMTPAETSPTM 521
P P+ P P G +P A TT K A T T TS T
Sbjct: 655 PAPTTPKETAPTT---------PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705
Query: 522 GPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPSP 566
P + E T P G A L+ P+P
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750
Score = 67.4 bits (163), Expect = 4e-11
Identities = 113/484 (23%), Positives = 168/484 (34%), Gaps = 72/484 (14%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQS 196
P +P+PS + T+L + + + E TT + + + K+T+A + QS
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKET---TTTNKQTSTDGKEKTTSAKET-QS 271
Query: 197 RPRVRSASLPPRTRL--------PSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSR 248
+ + L P +++ + ++ P+ PK + A+ + P P +
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP-KEPTPTTI 330
Query: 249 LAAPPLGSTTLPSTW-TAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRR 307
+AP P+T +AP + P+ + EP ++ P KEP P
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT------KEPA-PTT 383
Query: 308 EEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQ----KIPTPGQHQPILTPGHS 363
+ P +P P P++ P P P +P P TP +P K P P +P T
Sbjct: 384 TKSAPTTPKEPAPT-TPKK-PAPTTPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTP-K 439
Query: 364 QPIPT-PGQPLPPQPI-PTPGRPLTPQPI----PTPGRPLTPQPIQMPGRPLRLPPPLRL 417
+P PT P +P P P P P P P P P+P P P P P P
Sbjct: 440 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499
Query: 418 LRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAG-------RPLQPLPPGPDARSIS 466
P +P+ P P P P PK P P P P
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559
Query: 467 DPPAPRSRLPI-------RLLRGLLARLPGGASPRAAAAAACTTMKGWPAAT------MT 513
P P+ P + L P +P A TT + T T
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619
Query: 514 PAETSPTMGPPDASAGFSIGEIAAA-----------ESPSATYSATFSCKPSGAASVDLR 562
P E +PT P A+A + E A E T T P G A L+
Sbjct: 620 PEEPAPT--TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677
Query: 563 VPSP 566
P+P
Sbjct: 678 EPAP 681
Score = 53.5 bits (127), Expect = 6e-07
Identities = 95/432 (21%), Positives = 143/432 (33%), Gaps = 57/432 (13%)
Query: 108 PREAAVNFSYRSQTLLQE-AQVLQGSPELLPRSPKPSGLQRLAP----EEATALPLRRLC 162
P+E A + + T +E A S P+ P P+ + AP E A P
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP----- 532
Query: 163 HLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLP--PRTRLPSGSQAPSA 220
+K TT P+ + K A ++++ P P P+ P+ + +
Sbjct: 533 -----KKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585
Query: 221 AHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEP 280
P++L+ T AP P P T AP + A P+ EP
Sbjct: 586 TTPEKLAPT--TPEKPAP----TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639
Query: 281 QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPIL 340
++ P ++ P P+ +GT P +P P P +P P
Sbjct: 640 APTTPKEPAPTTPKEPA----PTTPKETAPTTPKGTAPTTLKEPA----PTTPKKPAPKE 691
Query: 341 TPGQPQKIPT------PGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPG 394
K PT P P T + P P P P P G T P P
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751
Query: 395 RPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQ 454
P P P ++ + P +P P +P ++T +P P PK P
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPA-PTTP--KETAPTTPKEP--APTTPKKPA-PTT 805
Query: 455 PLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP-----A 509
P P P +S P + I + P ++P +A ++ P
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIH-------KSPDESTPELSAEPTPKALENSPKEPGVP 858
Query: 510 ATMTPAETSPTM 521
T TPA T P M
Sbjct: 859 TTKTPAATKPEM 870
Score = 33.9 bits (76), Expect = 0.46
Identities = 68/338 (20%), Positives = 115/338 (34%), Gaps = 56/338 (16%)
Query: 132 SPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAA 191
+P+ L SPK G+ AT + E+DL TT K TA
Sbjct: 844 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 903
Query: 192 SSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAA 251
+ + + ++ + + T++ S + + P +++ L T+ A P+
Sbjct: 904 TEKTTESKITATT----TQVTSTTTQDTT--PFKITTLKTTTLA---------PKVTTTK 948
Query: 252 PPLGSTTL---PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRRE 308
+ +T + P P+ R T + +P+PQ + P +K + P+
Sbjct: 949 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1008
Query: 309 EKYPLRGTDPLPPGQP---------QRIPLPGQPLQPQPILTPGQPQKIPTPGQH----Q 355
P + T +P P Q P Q P L P+ G
Sbjct: 1009 PT-PRKMTSTMPELNPTSRIAEAMLQTTTRPNQ--TPNSKLVEVNPKSEDAGGAEGETPH 1065
Query: 356 PILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPL 415
+L P P TP P+ +P G + P L+ + G+P+ L
Sbjct: 1066 MLLRPHVFMPEVTPDMDYLPR-VPNQGIIINPM--------LSDETNICNGKPVDGLTTL 1116
Query: 416 R-------------LLRPGQPMSPQLRQTQGLPLPQPL 440
R +L P P SP R T+ +P P+
Sbjct: 1117 RNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPI 1154
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 69.7 bits (169), Expect = 8e-12
Identities = 96/405 (23%), Positives = 135/405 (33%), Gaps = 47/405 (11%)
Query: 186 KSTAAASSRQSRPRV-RSASLPPRTRLPSGSQAPSAAHPKRLSDLL------LTSRAAAP 238
K A ++++ P +SA P+ P+ + P+ PK + T + AP
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 469
Query: 239 GWRSPDPRS-RLAAPPLGSTTLPST--WTAPQSRLTARPSRSPEPQIRESEQRDPQLRRK 295
+ P P + + AP P+T AP + P+ + EP ++ P +
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529
Query: 296 QQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQ 355
+ P + P +P P + P P P +P P TP +P PT +
Sbjct: 530 APTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTTPKEPAPT-TPKKPA--PTTPKEP 584
Query: 356 PILTPGHSQPIPT--PGQPLPPQPIPTPGR---PLTPQPI-PTPGRPLTPQPIQMPGRPL 409
TP P T P P +P PT + P TP+ + PT L P + P
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--- 641
Query: 410 RLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAGRPLQPLPPGPDARSI 465
P L P P P + P P P P PK P P P P
Sbjct: 642 --PTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKE 695
Query: 466 SDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP----AATMTPAETSPTM 521
P P+ P P G +P A TT K A T T TS T
Sbjct: 696 PAPTTPKETAPTT---------PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 746
Query: 522 GPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLRVPSP 566
P + E T P G A L+ P+P
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791
Score = 67.4 bits (163), Expect = 4e-11
Identities = 113/484 (23%), Positives = 168/484 (34%), Gaps = 72/484 (14%)
Query: 137 PRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQS 196
P +P+PS + T+L + + + E TT + + + K+T+A + QS
Sbjct: 257 PINPRPSLPPNSDTSKETSLTVNKETTVETKET---TTTNKQTSTDGKEKTTSAKET-QS 312
Query: 197 RPRVRSASLPPRTRL--------PSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSR 248
+ + L P +++ + ++ P+ PK + A+ + P P +
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP-KEPTPTTI 371
Query: 249 LAAPPLGSTTLPSTW-TAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRR 307
+AP P+T +AP + P+ + EP ++ P KEP P
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT------KEPA-PTT 424
Query: 308 EEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQ----KIPTPGQHQPILTPGHS 363
+ P +P P P++ P P P +P P TP +P K P P +P T
Sbjct: 425 TKSAPTTPKEPAPT-TPKK-PAPTTPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTP-K 480
Query: 364 QPIPT-PGQPLPPQPI-PTPGRPLTPQPI----PTPGRPLTPQPIQMPGRPLRLPPPLRL 417
+P PT P +P P P P P P P P P+P P P P P P
Sbjct: 481 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540
Query: 418 LRPGQPMSPQLRQTQGLPLPQPLLP----PGQPKSAG-------RPLQPLPPGPDARSIS 466
P +P+ P P P P PK P P P P
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600
Query: 467 DPPAPRSRLPI-------RLLRGLLARLPGGASPRAAAAAACTTMKGWPAAT------MT 513
P P+ P + L P +P A TT + T T
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660
Query: 514 PAETSPTMGPPDASAGFSIGEIAAA-----------ESPSATYSATFSCKPSGAASVDLR 562
P E +PT P A+A + E A E T T P G A L+
Sbjct: 661 PEEPAPT--TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 718
Query: 563 VPSP 566
P+P
Sbjct: 719 EPAP 722
Score = 53.5 bits (127), Expect = 6e-07
Identities = 95/432 (21%), Positives = 143/432 (33%), Gaps = 57/432 (13%)
Query: 108 PREAAVNFSYRSQTLLQE-AQVLQGSPELLPRSPKPSGLQRLAP----EEATALPLRRLC 162
P+E A + + T +E A S P+ P P+ + AP E A P
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP----- 573
Query: 163 HLSLMEKDLGTTAHPRGFPELSHKSTAAASSRQSRPRVRSASLP--PRTRLPSGSQAPSA 220
+K TT P+ + K A ++++ P P P+ P+ + +
Sbjct: 574 -----KKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626
Query: 221 AHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEP 280
P++L+ T AP P P T AP + A P+ EP
Sbjct: 627 TTPEKLAPT--TPEKPAP----TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680
Query: 281 QIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPIL 340
++ P ++ P P+ +GT P +P P P +P P
Sbjct: 681 APTTPKEPAPTTPKEPA----PTTPKETAPTTPKGTAPTTLKEPA----PTTPKKPAPKE 732
Query: 341 TPGQPQKIPT------PGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPG 394
K PT P P T + P P P P P G T P P
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 395 RPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQ 454
P P P ++ + P +P P +P ++T +P P PK P
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPA-PTTP--KETAPTTPKEP--APTTPKKPA-PTT 846
Query: 455 PLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWP-----A 509
P P P +S P + I + P ++P +A ++ P
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIH-------KSPDESTPELSAEPTPKALENSPKEPGVP 899
Query: 510 ATMTPAETSPTM 521
T TPA T P M
Sbjct: 900 TTKTPAATKPEM 911
Score = 33.9 bits (76), Expect = 0.46
Identities = 68/338 (20%), Positives = 115/338 (34%), Gaps = 56/338 (16%)
Query: 132 SPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHKSTAAA 191
+P+ L SPK G+ AT + E+DL TT K TA
Sbjct: 885 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 944
Query: 192 SSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAA 251
+ + + ++ + + T++ S + + P +++ L T+ A P+
Sbjct: 945 TEKTTESKITATT----TQVTSTTTQDTT--PFKITTLKTTTLA---------PKVTTTK 989
Query: 252 PPLGSTTL---PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRRE 308
+ +T + P P+ R T + +P+PQ + P +K + P+
Sbjct: 990 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1049
Query: 309 EKYPLRGTDPLPPGQP---------QRIPLPGQPLQPQPILTPGQPQKIPTPGQH----Q 355
P + T +P P Q P Q P L P+ G
Sbjct: 1050 PT-PRKMTSTMPELNPTSRIAEAMLQTTTRPNQ--TPNSKLVEVNPKSEDAGGAEGETPH 1106
Query: 356 PILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPL 415
+L P P TP P+ +P G + P L+ + G+P+ L
Sbjct: 1107 MLLRPHVFMPEVTPDMDYLPR-VPNQGIIINPM--------LSDETNICNGKPVDGLTTL 1157
Query: 416 R-------------LLRPGQPMSPQLRQTQGLPLPQPL 440
R +L P P SP R T+ +P P+
Sbjct: 1158 RNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPI 1195
>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
Length = 1597
Score = 68.6 bits (166), Expect = 2e-11
Identities = 133/530 (25%), Positives = 177/530 (33%), Gaps = 73/530 (13%)
Query: 82 SVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYRSQTLLQEAQVLQGSPELLPRSPK 141
SV P + + + P++ S+ V F R + A +P L P
Sbjct: 508 SVTPPRTPDSAPPSPAEAYPITPASVSARPPVAFPRRETSCAARAPETASAP-LSMDDPS 566
Query: 142 PSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRG--FPELSHKSTAAASSRQSRPR 199
P G + P P GT H R FP SH++
Sbjct: 567 PCGTSEMCPAALYGFPSTGTSPPRPPANSTGTVQHLRSDSFPG-SHRTEQTPDLVGMLLS 625
Query: 200 VRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTL 259
+ LP R P+ S+ P+R RS S ++A P +TL
Sbjct: 626 YSHSELPQRPPKPA---IYSSVTPRR-------------DRRSGRDYSTVSASPTALSTL 669
Query: 260 PSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPL 319
S L RPS P Q S P E+ +R +PL
Sbjct: 670 KQDSQESISNLE-RPSSPPSIQPWVSPHNPAFATESPAYGSSPSFVSMED---VRIHEPL 725
Query: 320 PPGQPQRIPLPGQPLQPQPILTPGQPQKI-PTPGQHQ--PILTPGHSQPIPTPGQPLPPQ 376
PP PQR + P + T G + + PT QH P L G P G PLP
Sbjct: 726 PPPPPQR-----RDTHPSVVETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKG-PLPQA 779
Query: 377 PIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPL 436
P R Q P P P + Q R R PL P +P L
Sbjct: 780 SDPAVAR----QHRPLPSTPDSSHHAQATPR-WRYNKPL-------PPTPDL-------- 819
Query: 437 PQPLLPPGQPKSAGRPLQPLPPGPDARSISDPP--APRSRLPIRLLRGLLARLPGGASPR 494
PQP LPP + R +PLPP P ++PP P+SR R RG G A R
Sbjct: 820 PQPHLPPISAPGSSRIYRPLPPLPIIDPPTEPPPLPPKSRGRSRSTRGGHMNSGGHAKTR 879
Query: 495 AAA------AAACTTMKGWPAATMTPAE--TSPTMGPPDASAGFSIGEIAAAESPSATYS 546
A A WP AT E TS + + S G + + PS+
Sbjct: 880 PACQDWTVPLPASAGRTSWPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSS--- 936
Query: 547 ATFSCKPSGAASVDLRVPSPKPRA-LSRSRRYPWRRSADRCAKKPWRSGP 595
P+ + +L+ P+ K A +S P R R + SGP
Sbjct: 937 ------PTTPWTPELQGPTSKDEAGVSEHPEAPAREPLRRTTPQQGASGP 980
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 68.6 bits (166), Expect = 2e-11
Identities = 160/660 (24%), Positives = 242/660 (36%), Gaps = 118/660 (17%)
Query: 10 RSPDPTFRSS-TRHSGKLEPMEATAHLLRKQCPSRLNSPAWEASGLHWSSLDSPVGSMQA 68
RSP P RSS R K + H + + PS PA E + + P S++
Sbjct: 178 RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS----PAPEKKE---KTPELPEPSVKV 230
Query: 69 LRPSAQHSWS-------PEPSVVPDQAWEDTALHQKKLCPLSLT---------SLPREAA 112
PS Q + S P+P +P+ + KK T S R +
Sbjct: 231 KEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS 290
Query: 113 VNFSYRSQTLLQEAQVLQGSPELLPRSPK--PSGLQRLAPEEATALPLRRLCHLSLMEKD 170
+ S+ ++ SP P SP+ PS +R P P R + +
Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRRRP-SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349
Query: 171 LGTTAHPRGFPELSHKSTAAASSRQ----SRPRVRSASLPPRTRLPSGSQAPSAAHPKRL 226
R LS S++++SSR +P R++S P +TR S PSA+ P+R
Sbjct: 350 -------RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLS----PSASPPRR- 397
Query: 227 SDLLLTSRAAAPGWRSPDPRSRLAAPPLGST-TLPSTWTAPQSRLTARPSRSPEPQIRES 285
R + P +P P++R + P S T S + R + + ++ + RES
Sbjct: 398 -----RHRPSPPA--TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450
Query: 286 EQRDPQLRRKQ------------------QRWKEPLMPRREEKYPLRGTDPLPPGQPQRI 327
P+ R+ + Q+ ++ ++ + +P+R
Sbjct: 451 PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
Query: 328 PLPGQPLQPQPILTPGQPQKIPTPGQHQPILTP-GHSQPIPTPGQPLPPQPIPTPGRPLT 386
+ + + +P + P+P + Q +P G + P+P P R +
Sbjct: 511 HVKNGEVGRRRRHSPSRSAS-PSPRKRQKETSPRGRRRRSPSP---------PPTRRRRS 560
Query: 387 PQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQP----LLP 442
P P P P R TP P P R PPP R + SP + Q + P P P P
Sbjct: 561 PSPAPPPRRRRTPTP--PPRRRTPSPPPRRRSPSPRRYSPPI-QRRYSPSPPPKRRTASP 617
Query: 443 PGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLR--GLLARLPGGASP-RAAAAA 499
P PK R P PP S S PP RS P+ R L ++ G+SP R+ A
Sbjct: 618 PPPPK---RRASPSPPPKRRVSHSPPPKQRSS-PVTKRRSPSLSSKHRKGSSPSRSTREA 673
Query: 500 ACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAESPSATYSATFSCKPSGAASV 559
+ + P + PP G A+ SP S + S +P S
Sbjct: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRG-------ASSSPQRRQSPSPSTRPIRRVS- 725
Query: 560 DLRVPSPK--PRALSRSRRYPWRRSADR--------CAKKPWRSGPRSAQRRNAVSSSTN 609
R P PK +A S S + R S+ R AKKP P + S STN
Sbjct: 726 --RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP----PAPPSPVQSQSPSTN 779
Score = 50.1 bits (118), Expect = 6e-06
Identities = 93/405 (22%), Positives = 152/405 (37%), Gaps = 54/405 (13%)
Query: 241 RSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWK 300
RSP PR R + P+ S +P+ R +R S SP P E +++ P+L + K
Sbjct: 178 RSPSPRRR--SSPVRRERKRSHSRSPRHRTKSR-SPSPAP---EKKEKTPELPEPSVKVK 231
Query: 301 EPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTP 360
EP + +D L +P+ IP P +P P+ + ++ P +
Sbjct: 232 EPSVQEATST-----SDILKVPKPEPIPEPKEP-SPEKNSKKEKEKEKTRPRSRSRSKSR 285
Query: 361 GHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRP 420
++ +P P + + R +P+ P+P R +P+ + P P R+PPP R R
Sbjct: 286 SRTRS-RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR-RTP--PRRMPPPPRHRRS 341
Query: 421 GQPMSPQLRQTQGL--------------PLPQPLLPPGQPKSAGRPLQPLPPGPDARSIS 466
P+ + R + L P +P P R L P P R
Sbjct: 342 RSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRP 401
Query: 467 DPPA---------PRSRLPIRLLRGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAET 517
PPA P + R + ++ PG S + T + P+ P +
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG-TEKRESPSPAPKPRKV 460
Query: 518 SPTMGPPDASAGFSIGEIAAAESPSATYS------ATFSCKPSGAASVDLRVPSP--KPR 569
+ D G++AAA+S + S S ++S D R K
Sbjct: 461 ELSESEEDKG-----GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNG 515
Query: 570 ALSRSRRYPWRRSADRCAKKPWR-SGPRSAQRRNAVSSSTNNSRT 613
+ R RR+ RSA +K + + PR +RR+ T R+
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
Score = 34.3 bits (77), Expect = 0.35
Identities = 53/223 (23%), Positives = 85/223 (38%), Gaps = 48/223 (21%)
Query: 133 PELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELSHK----ST 188
P+ SP P +R +P P RR+ H S K + R P LS K S+
Sbjct: 610 PKRRTASPPPPPKRRASPSPP---PKRRVSH-SPPPKQRSSPVTKRRSPSLSSKHRKGSS 665
Query: 189 AAASSRQSR-----------PRVRS--------------ASLPPRTRLPSGSQAP----- 218
+ S+R++R PR R+ +S P R + PS S P
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS 725
Query: 219 ---------SAAHPKRLSDLLLTSRAAAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSR 269
AA P S ++S + G P + A P + PST +P
Sbjct: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
Query: 270 LTARPSRSPEPQ-IRESEQRDPQLRRKQQRWKEPLMPRREEKY 311
+ S +P P R S+Q ++K+++ K+ ++ +K+
Sbjct: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKH 828
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,421,398
Number of Sequences: 37866
Number of extensions: 2744441
Number of successful extensions: 37419
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 542
Number of HSP's successfully gapped in prelim test: 1917
Number of HSP's that attempted gapping in prelim test: 13535
Number of HSP's gapped (non-prelim): 11209
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.