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Search of human proteins with 10864037
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10864037 myosin light chain 2a [Homo sapiens]
(175 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10864037 myosin light chain 2a [Homo sapiens] 348 1e-96
gi|4505305 myosin regulatory light chain 5 [Homo sapiens] 226 8e-60
gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo s... 213 7e-56
gi|28372499 myosin light chain, phosphorylatable, fast skeletal ... 210 6e-55
gi|34147532 myosin, light chain 10, regulatory [Homo sapiens] 198 2e-51
gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric [... 170 5e-43
gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo... 169 9e-43
gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo... 169 9e-43
gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo ... 169 9e-43
gi|29568111 myosin regulatory light chain 9 isoform a [Homo sapi... 168 2e-42
gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo... 156 1e-38
gi|88981341 PREDICTED: similar to myosin regulatory light chain ... 147 4e-36
gi|51464364 PREDICTED: similar to myosin regulatory light chain ... 147 4e-36
gi|169167243 PREDICTED: similar to myosin regulatory light chain... 144 3e-35
gi|58218968 calmodulin 3 [Homo sapiens] 89 2e-18
gi|4502549 calmodulin 2 [Homo sapiens] 89 2e-18
gi|5901912 calmodulin 1 [Homo sapiens] 89 2e-18
gi|4885111 calmodulin-like 3 [Homo sapiens] 84 5e-17
gi|31563524 myosin regulatory light chain 9 isoform b [Homo sapi... 80 1e-15
gi|110227594 calmodulin-like 4 isoform 1 [Homo sapiens] 70 9e-13
gi|4757902 caltractin [Homo sapiens] 61 6e-10
gi|50897266 calmodulin-like 6 [Homo sapiens] 59 2e-09
gi|4757974 centrin 1 [Homo sapiens] 59 3e-09
gi|4507617 fast skeletal muscle troponin C [Homo sapiens] 57 8e-09
gi|4507615 troponin C, slow [Homo sapiens] 55 3e-08
gi|4505303 smooth muscle and non-muscle myosin alkali light chai... 53 1e-07
gi|223278387 calmodulin-like 5 [Homo sapiens] 52 3e-07
gi|88999583 myosin, light chain 6, alkali, smooth muscle and non... 52 3e-07
gi|110227596 calmodulin-like 4 isoform 2 [Homo sapiens] 51 6e-07
gi|4557038 atrial/embryonic alkali myosin light chain [Homo sapi... 50 1e-06
>gi|10864037 myosin light chain 2a [Homo sapiens]
Length = 175
Score = 348 bits (893), Expect = 1e-96
Identities = 175/175 (100%), Positives = 175/175 (100%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
Sbjct: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
Sbjct: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
Sbjct: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
>gi|4505305 myosin regulatory light chain 5 [Homo sapiens]
Length = 173
Score = 226 bits (576), Expect = 8e-60
Identities = 111/175 (63%), Positives = 139/175 (79%), Gaps = 2/175 (1%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
MASRK T+ K +AQR SSNVFS FEQ QIQEFKEAF+ +DQNRDG I K DL++T
Sbjct: 1 MASRK--TKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT 58
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
Y+ LGK +V ++ELDAML+E GPINFT+FL LFGEKL+GTD EE IL+AF+M DP GKG
Sbjct: 59 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG 118
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+NK+ K+LL++QADK + EV+QMF +D+AGN+DYK+L Y+ITHG+EKEE
Sbjct: 119 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE 173
>gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo
sapiens]
Length = 166
Score = 213 bits (542), Expect = 7e-56
Identities = 101/161 (62%), Positives = 130/161 (80%)
Query: 14 ATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEE 73
A K+A +SNVFSMFEQ QIQEFKEAF+ +DQNRDG I K DLR+T++ LG+V+V EE
Sbjct: 6 AKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEE 65
Query: 74 LDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLT 133
+D M++E GPINFTVFLT+FGEKL G DPEE IL+AF++FDP GKGV+ D +++L T
Sbjct: 66 IDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTT 125
Query: 134 QADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKE 174
QA++FS EV+QMFA P D+ GN+DYK+L +IITHG+EK+
Sbjct: 126 QAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD 166
>gi|28372499 myosin light chain, phosphorylatable, fast skeletal
muscle [Homo sapiens]
Length = 169
Score = 210 bits (534), Expect = 6e-55
Identities = 96/165 (58%), Positives = 128/165 (77%)
Query: 11 KVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVP 70
K A + + GSS+VFSMF+Q QIQEFKEAF+ IDQNRDGII K DLR+T++ +G+++V
Sbjct: 4 KRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVK 63
Query: 71 EEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQL 130
EELDAM++E GPINFTVFLT+FGEKL G DPE+ I AF++ DP GKG + K ++L
Sbjct: 64 NEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFLEEL 123
Query: 131 LLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
L TQ D+FS E++ M+A P D+ GN+DYK++CY+ITHGD K++
Sbjct: 124 LTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAKDQ 168
>gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]
Length = 226
Score = 198 bits (504), Expect = 2e-51
Identities = 104/203 (51%), Positives = 134/203 (66%), Gaps = 35/203 (17%)
Query: 7 GTRGKVAATKQAQ-RGSSNVFSMFEQAQIQEFKE-------------------------- 39
G + A K+A+ SSNVFSMF+Q+QIQEFKE
Sbjct: 24 GLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLALSPRLERNGMISAHCNLCLTGSS 83
Query: 40 --------AFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFTVFL 91
AF+ +DQNRDG I K DLR+T++ LG+++V EEL+AM++E GPINFTVFL
Sbjct: 84 NSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPINFTVFL 143
Query: 92 TLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTP 151
T+FGEKL GTDPEE IL AF++FD GKG V D K+ L+TQAD+FS EV+QMFA P
Sbjct: 144 TMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIKEKLMTQADRFSEEEVKQMFAAFP 203
Query: 152 MDLAGNIDYKSLCYIITHGDEKE 174
D+ GN+DY++LCY+ITHG+EK+
Sbjct: 204 PDVCGNLDYRNLCYVITHGEEKD 226
>gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric
[Homo sapiens]
Length = 171
Score = 170 bits (431), Expect = 5e-43
Identities = 85/175 (48%), Positives = 120/175 (68%), Gaps = 5/175 (2%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
M+S++ T+ K K+ QR +SNVF+MF+Q+QIQEFKEAF+ IDQNRDG I K DL +
Sbjct: 1 MSSKRTKTKTK----KRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM 56
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
+ LGK + +E LDAM+ E GPINFT+FLT+FGEKLNGTDPE+ I +AF FD G
Sbjct: 57 LASLGK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG 115
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+ +D ++LL T D+F+ EV++++ P+D GN +Y I+ HG + ++
Sbjct: 116 TIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKD 170
>gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 169 bits (429), Expect = 9e-43
Identities = 85/175 (48%), Positives = 119/175 (68%), Gaps = 4/175 (2%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
M+S+KA T+ K+ QR +SNVF+MF+Q+QIQEFKEAF+ IDQNRDG I K DL +
Sbjct: 1 MSSKKAKTK---TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM 57
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
+ LGK + + LDAM+ E GPINFT+FLT+FGEKLNGTDPE+ I +AF FD G
Sbjct: 58 LASLGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG 116
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+ +D ++LL T D+F+ EV++++ P+D GN +Y I+ HG + ++
Sbjct: 117 TIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKD 171
>gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 169 bits (429), Expect = 9e-43
Identities = 85/175 (48%), Positives = 119/175 (68%), Gaps = 4/175 (2%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
M+S+KA T+ K+ QR +SNVF+MF+Q+QIQEFKEAF+ IDQNRDG I K DL +
Sbjct: 1 MSSKKAKTK---TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM 57
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
+ LGK + + LDAM+ E GPINFT+FLT+FGEKLNGTDPE+ I +AF FD G
Sbjct: 58 LASLGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG 116
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+ +D ++LL T D+F+ EV++++ P+D GN +Y I+ HG + ++
Sbjct: 117 TIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKD 171
>gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 169 bits (429), Expect = 9e-43
Identities = 85/175 (48%), Positives = 119/175 (68%), Gaps = 4/175 (2%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
M+S+KA T+ K+ QR +SNVF+MF+Q+QIQEFKEAF+ IDQNRDG I K DL +
Sbjct: 1 MSSKKAKTK---TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM 57
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
+ LGK + + LDAM+ E GPINFT+FLT+FGEKLNGTDPE+ I +AF FD G
Sbjct: 58 LASLGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG 116
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+ +D ++LL T D+F+ EV++++ P+D GN +Y I+ HG + ++
Sbjct: 117 TIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKD 171
>gi|29568111 myosin regulatory light chain 9 isoform a [Homo
sapiens]
Length = 172
Score = 168 bits (426), Expect = 2e-42
Identities = 83/175 (47%), Positives = 119/175 (68%), Gaps = 4/175 (2%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
M+S++A + K+ QR +SNVF+MF+Q+QIQEFKEAF+ IDQNRDG I K DL +
Sbjct: 1 MSSKRAKAK---TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM 57
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
+ LGK + +E L+ M+ E GPINFT+FLT+FGEKLNGTDPE+ I +AF FD G
Sbjct: 58 LASLGK-NPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASG 116
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+++D ++LL T D+F+ EV++M+ P+D GN +Y I+ HG + ++
Sbjct: 117 FIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKD 171
>gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo
sapiens]
Length = 154
Score = 156 bits (394), Expect = 1e-38
Identities = 75/153 (49%), Positives = 106/153 (69%), Gaps = 1/153 (0%)
Query: 23 SNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGK 82
S++F+MF+Q+QIQEFKEAF+ IDQNRDG I K DL + + LGK + + LDAM+ E
Sbjct: 2 SSMFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGK-NPTDAYLDAMMNEAP 60
Query: 83 GPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAE 142
GPINFT+FLT+FGEKLNGTDPE+ I +AF FD G + +D ++LL T D+F+ E
Sbjct: 61 GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEE 120
Query: 143 VEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
V++++ P+D GN +Y I+ HG + ++
Sbjct: 121 VDELYREAPIDKKGNFNYIEFTRILKHGAKDKD 153
>gi|88981341 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 147 bits (372), Expect = 4e-36
Identities = 73/155 (47%), Positives = 102/155 (65%), Gaps = 1/155 (0%)
Query: 16 KQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELD 75
K+ Q +S VF+ F+Q+QIQEFKEAF+ IDQNRDG I K DL + LGK + + LD
Sbjct: 218 KRPQCATSKVFATFDQSQIQEFKEAFNMIDQNRDGFISKEDLHGMLASLGK-NPTDACLD 276
Query: 76 AMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQA 135
A++ E GPINFT+ L +FG+KLNGTDPE+ I +AF FD G + +D ++LL T
Sbjct: 277 AVMNEAPGPINFTMLLAMFGKKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTVG 336
Query: 136 DKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHG 170
D+F+ EV++++ P+D GN +Y I+ HG
Sbjct: 337 DQFTDEEVDELYTEAPIDKKGNFNYIEFTSILKHG 371
>gi|51464364 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 147 bits (372), Expect = 4e-36
Identities = 73/155 (47%), Positives = 102/155 (65%), Gaps = 1/155 (0%)
Query: 16 KQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELD 75
K+ Q +S VF+ F+Q+QIQEFKEAF+ IDQNRDG I K DL + LGK + + LD
Sbjct: 218 KRPQCATSKVFATFDQSQIQEFKEAFNMIDQNRDGFISKEDLHGMLASLGK-NPTDACLD 276
Query: 76 AMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQA 135
A++ E GPINFT+ L +FG+KLNGTDPE+ I +AF FD G + +D ++LL T
Sbjct: 277 AVMNEAPGPINFTMLLAMFGKKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTVG 336
Query: 136 DKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHG 170
D+F+ EV++++ P+D GN +Y I+ HG
Sbjct: 337 DQFTDEEVDELYTEAPIDKKGNFNYIEFTSILKHG 371
>gi|169167243 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 144 bits (364), Expect = 3e-35
Identities = 72/155 (46%), Positives = 101/155 (65%), Gaps = 1/155 (0%)
Query: 16 KQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELD 75
K+ Q +S VF+ F+Q+QIQEFKEAF+ IDQNRDG I K DL + LGK + + LD
Sbjct: 218 KRPQCATSKVFATFDQSQIQEFKEAFNMIDQNRDGFISKEDLHGMLASLGK-NPTDACLD 276
Query: 76 AMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQA 135
A++ E GPINFT+ L +FG+KLNGTDPE+ I +AF FD G + +D ++LL T
Sbjct: 277 AVMNEAPGPINFTMLLAMFGKKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTVG 336
Query: 136 DKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHG 170
D+F+ EV++++ +D GN +Y I+ HG
Sbjct: 337 DQFTDEEVDELYTEASIDKKGNFNYIEFTSILKHG 371
>gi|58218968 calmodulin 3 [Homo sapiens]
Length = 149
Score = 89.0 bits (219), Expect = 2e-18
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 5/142 (3%)
Query: 31 QAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GKGPIN 86
+ QI EFKEAFS D++ DG I +L LG+ + E EL M+ E G G I+
Sbjct: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NPTEAELQDMINEVDADGNGTID 65
Query: 87 FTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQM 146
F FLT+ K+ TD EE I AFR+FD G G ++ E + ++ +K + EV++M
Sbjct: 66 FPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 125
Query: 147 FALTPMDLAGNIDYKSLCYIIT 168
+D G ++Y+ ++T
Sbjct: 126 IREADIDGDGQVNYEEFVQMMT 147
>gi|4502549 calmodulin 2 [Homo sapiens]
Length = 149
Score = 89.0 bits (219), Expect = 2e-18
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 5/142 (3%)
Query: 31 QAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GKGPIN 86
+ QI EFKEAFS D++ DG I +L LG+ + E EL M+ E G G I+
Sbjct: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NPTEAELQDMINEVDADGNGTID 65
Query: 87 FTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQM 146
F FLT+ K+ TD EE I AFR+FD G G ++ E + ++ +K + EV++M
Sbjct: 66 FPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 125
Query: 147 FALTPMDLAGNIDYKSLCYIIT 168
+D G ++Y+ ++T
Sbjct: 126 IREADIDGDGQVNYEEFVQMMT 147
>gi|5901912 calmodulin 1 [Homo sapiens]
Length = 149
Score = 89.0 bits (219), Expect = 2e-18
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 5/142 (3%)
Query: 31 QAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GKGPIN 86
+ QI EFKEAFS D++ DG I +L LG+ + E EL M+ E G G I+
Sbjct: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NPTEAELQDMINEVDADGNGTID 65
Query: 87 FTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQM 146
F FLT+ K+ TD EE I AFR+FD G G ++ E + ++ +K + EV++M
Sbjct: 66 FPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 125
Query: 147 FALTPMDLAGNIDYKSLCYIIT 168
+D G ++Y+ ++T
Sbjct: 126 IREADIDGDGQVNYEEFVQMMT 147
>gi|4885111 calmodulin-like 3 [Homo sapiens]
Length = 149
Score = 84.3 bits (207), Expect = 5e-17
Identities = 46/140 (32%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Query: 31 QAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQ---EGKGPINF 87
+ Q+ EFKEAFS D++ DG I +L LG+ E D M + +G G ++F
Sbjct: 7 EEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDF 66
Query: 88 TVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMF 147
FL + K+ TD EE I AFR+FD G G V+ E + ++ +K S EV++M
Sbjct: 67 PEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMI 126
Query: 148 ALTPMDLAGNIDYKSLCYII 167
D G ++Y+ ++
Sbjct: 127 RAADTDGDGQVNYEEFVRVL 146
>gi|31563524 myosin regulatory light chain 9 isoform b [Homo
sapiens]
Length = 118
Score = 79.7 bits (195), Expect = 1e-15
Identities = 53/175 (30%), Positives = 81/175 (46%), Gaps = 58/175 (33%)
Query: 1 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 60
M+S++A + K+ QR +SNVF+MF+Q+QIQEFKEAF+ IDQNRDG I K
Sbjct: 1 MSSKRAKAK---TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDK------ 51
Query: 61 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 120
E+L ML + G
Sbjct: 52 -----------EDLHDML--------------------------------------ASLG 62
Query: 121 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 175
+++D ++LL T D+F+ EV++M+ P+D GN +Y I+ HG + ++
Sbjct: 63 FIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKD 117
>gi|110227594 calmodulin-like 4 isoform 1 [Homo sapiens]
Length = 196
Score = 70.1 bits (170), Expect = 9e-13
Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 3/170 (1%)
Query: 2 ASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETY 61
A K RG ++ + Q QI E+KE FS D+ + G I DL
Sbjct: 21 AGGKGTERGSGSSKPTGSSRGPRMAKFLSQDQINEYKECFSLYDKQQRGKIKATDLMVAM 80
Query: 62 SQLGKVSVPEE---ELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSG 118
LG P E L +G G ++F+ FLT+ ++ DP++ IL A M D
Sbjct: 81 RCLGASPTPGEVQRHLQTHGIDGNGELDFSTFLTIMHMQIKQEDPKKEILLAMLMVDKEK 140
Query: 119 KGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIIT 168
KG V + + L + +K + EV+ +F ++ G + Y + IT
Sbjct: 141 KGYVMASDLRSKLTSLGEKLTHKEVDDLFREADIEPNGKVKYDEFIHKIT 190
>gi|4757902 caltractin [Homo sapiens]
Length = 172
Score = 60.8 bits (146), Expect = 6e-10
Identities = 43/163 (26%), Positives = 77/163 (47%), Gaps = 7/163 (4%)
Query: 9 RGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVS 68
+ +A++ Q +R S + Q QE +EAF D + G I +L+ LG
Sbjct: 7 KANMASSSQRKRMSPK--PELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALG-FE 63
Query: 69 VPEEELDAML----QEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNK 124
+EE+ M+ +EG G +NF FLT+ +K++ D +E IL AF++FD G ++
Sbjct: 64 PKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISF 123
Query: 125 DEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYII 167
K++ + + E+++M D G + + I+
Sbjct: 124 KNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIM 166
Score = 28.1 bits (61), Expect = 4.1
Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 102 DPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYK 161
+ ++ I AF +FD G G ++ E K + + E+++M + + G +++
Sbjct: 28 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFG 87
Query: 162 SLCYIIT----HGDEKEE 175
++T D KEE
Sbjct: 88 DFLTVMTQKMSEKDTKEE 105
>gi|50897266 calmodulin-like 6 [Homo sapiens]
Length = 181
Score = 59.3 bits (142), Expect = 2e-09
Identities = 43/143 (30%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 33 QIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GKGPINFT 88
QI+E+K F D+ +G + +L S LG ++ + EL +M ++ KG N
Sbjct: 34 QIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLG-INPTKSELASMAKDVDRDNKGFFNCD 92
Query: 89 VFLTLFG---EKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQ 145
FL L G EK + E + +AFR+FD GKG ++ + K +L+ + + E EQ
Sbjct: 93 GFLALMGVYHEKAQNQESE--LRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQ 150
Query: 146 MFALTPMDLAGNIDYKSLCYIIT 168
M D IDY+ ++T
Sbjct: 151 MMKEADKDGDRTIDYEEFVAMMT 173
>gi|4757974 centrin 1 [Homo sapiens]
Length = 172
Score = 58.5 bits (140), Expect = 3e-09
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 5/139 (3%)
Query: 33 QIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAML----QEGKGPINFT 88
Q QE +EAF D + G I +L+ LG +EE+ M+ +EG G I+F
Sbjct: 29 QKQEVREAFDLFDVDGSGTIDAKELKVAMRALG-FEPRKEEMKKMISEVDREGTGKISFN 87
Query: 89 VFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFA 148
FL + +K++ D +E IL AFR+FD G ++ K++ + + E+++M
Sbjct: 88 DFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMID 147
Query: 149 LTPMDLAGNIDYKSLCYII 167
D G ++ + I+
Sbjct: 148 EADRDGDGEVNEEEFLRIM 166
Score = 31.2 bits (69), Expect = 0.48
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 28 MFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GKG 83
M E+ +E +AF D + G I +L+ ++LG+ ++ +EEL M+ E G G
Sbjct: 97 MSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE-NLTDEELQEMIDEADRDGDG 155
Query: 84 PINFTVFLTL 93
+N FL +
Sbjct: 156 EVNEEEFLRI 165
Score = 30.4 bits (67), Expect = 0.82
Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
Query: 102 DPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYK 161
D ++ + AF +FD G G ++ E K + + E+++M + + G I +
Sbjct: 28 DQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFN 87
Query: 162 SLCYIIT----HGDEKEE 175
++T D KEE
Sbjct: 88 DFLAVMTQKMSEKDTKEE 105
>gi|4507617 fast skeletal muscle troponin C [Homo sapiens]
Length = 160
Score = 57.0 bits (136), Expect = 8e-09
Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 8/141 (5%)
Query: 27 SMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GK 82
S + I EFK AF D + G I +L LG+ +EELDA+++E G
Sbjct: 10 SYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPT-KEELDAIIEEVDEDGS 68
Query: 83 GPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFS 139
G I+F FL + ++ EE + FR+FD + G ++ +E ++ + +
Sbjct: 69 GTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHVT 128
Query: 140 PAEVEQMFALTPMDLAGNIDY 160
E+E + + G ID+
Sbjct: 129 DEEIESLMKDGDKNNDGRIDF 149
>gi|4507615 troponin C, slow [Homo sapiens]
Length = 161
Score = 55.1 bits (131), Expect = 3e-08
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 7/137 (5%)
Query: 31 QAQIQEFKEAFSCIDQN-RDGIICKADLRETYSQLGKVSVPEE---ELDAMLQEGKGPIN 86
+ Q EFK AF DG I +L + LG+ PEE +D + ++G G ++
Sbjct: 14 EEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 73
Query: 87 FTVFLTLFGEKLNGTDP---EEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEV 143
F FL + + EE + FRMFD + G ++ DE K +L + + ++
Sbjct: 74 FDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDI 133
Query: 144 EQMFALTPMDLAGNIDY 160
E++ + G IDY
Sbjct: 134 EELMKDGDKNNDGRIDY 150
>gi|4505303 smooth muscle and non-muscle myosin alkali light chain
6B [Homo sapiens]
Length = 208
Score = 53.1 bits (126), Expect = 1e-07
Identities = 44/147 (29%), Positives = 64/147 (43%), Gaps = 8/147 (5%)
Query: 23 SNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGK 82
S V F + Q++EFKEAF D+ DG I + + LG+ E L +
Sbjct: 55 SKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKS 114
Query: 83 GP-----INFTVFLTLFGE--KLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQA 135
++F FL + K G E L FR+FD G G V E + +L T
Sbjct: 115 DELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLG 174
Query: 136 DKFSPAEVEQMFALTPMDLAGNIDYKS 162
+K + EVE + A D G I+Y++
Sbjct: 175 EKMTEEEVETVLA-GHEDSNGCINYEA 200
>gi|223278387 calmodulin-like 5 [Homo sapiens]
Length = 146
Score = 52.0 bits (123), Expect = 3e-07
Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 8/136 (5%)
Query: 36 EFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE----GKGPINFTVFL 91
++K+AFS +D + +G I +L GK ++ E +L ++ E G G I+F FL
Sbjct: 12 QYKKAFSAVDTDGNGTINAQELGAALKATGK-NLSEAQLRKLISEVDSDGDGEISFQEFL 70
Query: 92 TLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTP 151
T + G E + AFR FD G G + DE ++ + E++ M
Sbjct: 71 TAAKKARAGL---EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREAD 127
Query: 152 MDLAGNIDYKSLCYII 167
+D G ++Y+ ++
Sbjct: 128 VDQDGRVNYEEFARML 143
Score = 41.2 bits (95), Expect = 5e-04
Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 5/71 (7%)
Query: 31 QAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEG----KGPIN 86
+A +++ + AF DQ+ DG I +LR + LG+ +P+EELDAM++E G +N
Sbjct: 77 RAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQ-PLPQEELDAMIREADVDQDGRVN 135
Query: 87 FTVFLTLFGEK 97
+ F + ++
Sbjct: 136 YEEFARMLAQE 146
>gi|88999583 myosin, light chain 6, alkali, smooth muscle and
non-muscle isoform 2 [Homo sapiens]
Length = 151
Score = 51.6 bits (122), Expect = 3e-07
Identities = 42/149 (28%), Positives = 63/149 (42%), Gaps = 8/149 (5%)
Query: 29 FEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFT 88
F + Q EFKEAF D+ DG I + + LG+ E L + +N
Sbjct: 4 FTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVK 63
Query: 89 V-----FLTLFGEKLNGTDPE--EAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPA 141
V FL + D E + R+FD G G V E + +L+T +K +
Sbjct: 64 VLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEE 123
Query: 142 EVEQMFALTPMDLAGNIDYKSLCYIITHG 170
EVE + A D G I+Y+ L ++ +G
Sbjct: 124 EVEMLVA-GHEDSNGCINYEELVRMVLNG 151
>gi|110227596 calmodulin-like 4 isoform 2 [Homo sapiens]
Length = 149
Score = 50.8 bits (120), Expect = 6e-07
Identities = 25/91 (27%), Positives = 46/91 (50%)
Query: 78 LQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADK 137
+ +G G ++F+ FLT+ ++ DP++ IL A M D KG V + + L + +K
Sbjct: 53 INDGNGELDFSTFLTIMHMQIKQEDPKKEILLAMLMVDKEKKGYVMASDLRSKLTSLGEK 112
Query: 138 FSPAEVEQMFALTPMDLAGNIDYKSLCYIIT 168
+ EV+ +F ++ G + Y + IT
Sbjct: 113 LTHKEVDDLFREADIEPNGKVKYDEFIHKIT 143
>gi|4557038 atrial/embryonic alkali myosin light chain [Homo
sapiens]
Length = 197
Score = 49.7 bits (117), Expect = 1e-06
Identities = 48/158 (30%), Positives = 70/158 (44%), Gaps = 24/158 (15%)
Query: 29 FEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKV------SVPEEELDAMLQEGK 82
F QI+EFKEAFS D+ G +++ TY Q G V + E+ +L + K
Sbjct: 48 FTADQIEEFKEAFSLFDRTPTG-----EMKITYGQCGDVLRALGQNPTNAEVLRVLGKPK 102
Query: 83 GP------INFTVFLTLFGE----KLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLL 132
++F FL + K GT E + R+FD G V E + +L
Sbjct: 103 PEEMNVKMLDFETFLPILQHISRNKEQGT--YEDFVEGLRVFDKESNGTVMGAELRHVLA 160
Query: 133 TQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHG 170
T +K + AEVEQ+ A D G I+Y++ I G
Sbjct: 161 TLGEKMTEAEVEQLLA-GQEDANGCINYEAFVKHIMSG 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,365,776
Number of Sequences: 37866
Number of extensions: 274665
Number of successful extensions: 945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 729
Number of HSP's gapped (non-prelim): 218
length of query: 175
length of database: 18,247,518
effective HSP length: 95
effective length of query: 80
effective length of database: 14,650,248
effective search space: 1172019840
effective search space used: 1172019840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.