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Search of human proteins with 10864029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10864029 junctional adhesion molecule 2 precursor [Homo
sapiens]
(298 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 593 e-170
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 186 2e-47
gi|8393638 F11 receptor precursor [Homo sapiens] 166 2e-41
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 85 7e-17
gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 75 5e-14
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 71 1e-12
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 70 2e-12
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 70 3e-12
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 70 3e-12
gi|118572606 hemicentin 1 [Homo sapiens] 67 1e-11
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 65 7e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 62 6e-10
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 60 2e-09
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 59 4e-09
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 59 4e-09
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 59 4e-09
gi|54792136 follistatin-like 4 [Homo sapiens] 59 7e-09
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 59 7e-09
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens] 58 9e-09
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens] 58 9e-09
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens] 58 9e-09
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens] 58 9e-09
gi|109150416 peroxidasin [Homo sapiens] 58 1e-08
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 56 4e-08
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 55 6e-08
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 55 6e-08
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 55 6e-08
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 55 7e-08
gi|190358524 follistatin-like 5 isoform c [Homo sapiens] 55 7e-08
gi|190358522 follistatin-like 5 isoform b [Homo sapiens] 55 7e-08
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 593 bits (1528), Expect = e-170
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 1 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR 60
MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR
Sbjct: 1 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR 60
Query: 61 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN 120
LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN
Sbjct: 61 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN 120
Query: 121 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR 180
LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR
Sbjct: 121 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR 180
Query: 181 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI 240
LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI
Sbjct: 181 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI 240
Query: 241 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII 298
IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII
Sbjct: 241 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII 298
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 186 bits (472), Expect = 2e-47
Identities = 101/267 (37%), Positives = 156/267 (58%), Gaps = 11/267 (4%)
Query: 42 EYQEAILACK-TPKKTVSSRLEWKKL-GRSVSFVYYQQTLQGDFKNRAEMID-FNIRIKN 98
E++ L+C T +T R+EWKK+ ++V++ +QGD RAE++ +++I N
Sbjct: 90 EFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWN 149
Query: 99 VTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK 158
VTR D+ YRCEV A +++ + ++E + L V V P P C VP + G + L CQ+
Sbjct: 150 VTRRDSALYRCEVVARNDR-KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQES 208
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
EG+P P Y+W+++ + L + R + NSS+ +N++TGTL F V K D+G+Y C A N
Sbjct: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
Query: 219 SVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKE----TSFQ 274
G RC + M+V DLNI GII V+VV V+++ LG+C A R+GYF S++
Sbjct: 269 DAGSARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYK 328
Query: 275 ---KSNSSSKATTMSENDFKHTKSFII 298
K + + T E DF+H SF+I
Sbjct: 329 NPGKPDGVNYIRTDEEGDFRHKSSFVI 355
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 166 bits (420), Expect = 2e-41
Identities = 94/245 (38%), Positives = 137/245 (55%), Gaps = 6/245 (2%)
Query: 58 SSRLEWK-KLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSE 116
S R+EWK G + V Y + +++R + I K+VTR D G Y C VS E
Sbjct: 57 SPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVS--EE 114
Query: 117 QGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLL 176
G + E V L VLV P+ P+ +PSSA G L C +++G+P EYTWFKDGI +
Sbjct: 115 GGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMP 174
Query: 177 ENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK-RMQVDDL 235
NP+ +NSSY +N TG L F+ +S DTGEYSCEARN G RM+ +
Sbjct: 175 TNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVER 234
Query: 236 NISGIIAAVVVVALVISVCGLGVCYAQRKGYF--SKETSFQKSNSSSKATTMSENDFKHT 293
N+ I+AAV+V +++ + G+ +A +G+F +K+ + K S+ + SE +FK T
Sbjct: 235 NVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQT 294
Query: 294 KSFII 298
SF++
Sbjct: 295 SSFLV 299
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 85.1 bits (209), Expect = 7e-17
Identities = 71/249 (28%), Positives = 113/249 (45%), Gaps = 36/249 (14%)
Query: 30 SAPKDQQVVTAVEYQEAILACKTPKKTVSSR---LEWKKL-----GRSVSFVYYQQT-LQ 80
S Q V+ A + + L C T + SSR ++W KL R V + + + +
Sbjct: 23 SVETPQDVLRASQGKSVTLPC-TYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIH 81
Query: 81 GD-FKNR------AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVA 133
G+ +KNR AE D +I I +T +D G Y C VS S+ N + V L VLV
Sbjct: 82 GELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKS-RVRLLVLVP 140
Query: 134 PAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMN 193
P+ P C + + G ++L CQ KEG+P P+Y+W + I E P S N
Sbjct: 141 PSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKN 200
Query: 194 TKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCP-GKRMQVDDLNIS-------GIIAAVV 245
T T +G Y C + N G + C ++ +N++ G++AA++
Sbjct: 201 ISTDT----------SGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALI 250
Query: 246 VVALVISVC 254
++ ++I C
Sbjct: 251 IIGIIIYCC 259
>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
Length = 390
Score = 75.5 bits (184), Expect = 5e-14
Identities = 53/170 (31%), Positives = 82/170 (48%), Gaps = 16/170 (9%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLE--VLVAPAVPSCEVPSSALSG 148
+ ++R++ + D+G Y C V+ +QG++ TLE VLV PA PSC + G
Sbjct: 108 NLSLRLEGLQEKDSGPYSCSVNVQDKQGKSRGHSIKTLELNVLVPPAPPSCRLQGVPHVG 167
Query: 149 TVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
V L CQ PA +Y W + +L S T + ++ G+L +S
Sbjct: 168 ANVTLSCQSPRSKPAVQYQW---------DRQLPSFQTFFAPALDVIRGSLSLTNLSSSM 218
Query: 209 TGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGV 258
G Y C+A N VG +C ++V +G AAVV A+V ++ GLG+
Sbjct: 219 AGVYVCKAHNEVGTAQC-NVTLEVS----TGPGAAVVAGAVVGTLVGLGL 263
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 71.2 bits (173), Expect = 1e-12
Identities = 67/230 (29%), Positives = 105/230 (45%), Gaps = 38/230 (16%)
Query: 56 TVSSR----LEW----KKLGRSVSFVYYQQTLQ----GDFKNRA----EMIDFNIRIKNV 99
TV+SR ++W KK +S +Y+ Q Q G FK+R + + +I I ++
Sbjct: 48 TVASREQLSIQWSFFHKKEMEPIS-IYFSQGGQAVAIGQFKDRITGSNDPGNASITISHM 106
Query: 100 TRSDAGKYRCEVSAPSE-QGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK 158
+D+G Y C+V+ P + GQN + + + VLV P+ P C V +G + L C
Sbjct: 107 QPADSGIYICDVNNPPDFLGQN--QGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSA 164
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
G P+P Y W K LE G N TG L ++ + G Y C A N
Sbjct: 165 LGTPSPVYYWHK-----LE----GRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAIN 215
Query: 219 SVGYRRC----PGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRK 264
+G C +V + + +I ++V A++ISV VC+A+ K
Sbjct: 216 RLGNSSCEIDLTSSHPEV-GIIVGALIGSLVGAAIIISV----VCFARNK 260
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 70.1 bits (170), Expect = 2e-12
Identities = 67/288 (23%), Positives = 125/288 (43%), Gaps = 39/288 (13%)
Query: 10 LLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACK---TPKKTVSSRLEW--- 63
+ LLL ++++ A S ++++ + + A L CK +P+ +EW
Sbjct: 1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS 60
Query: 64 ----KKLGRSVSFVYYQQTLQGDF-----------KNRAEMIDFNIRIKNVTRSDAGKYR 108
+K+ + V +Y + D+ N + D +I + N+ SD G Y+
Sbjct: 61 PADNQKVDQ-VIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ 119
Query: 109 CEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTW 168
C+V ++ + + L VLV P+ C V S G+ +++C+ KEG+ +Y W
Sbjct: 120 CKV----KKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEW 175
Query: 169 FKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK 228
K SQ +S+ + + S +G YSC RN VG +C +
Sbjct: 176 QKLS---------DSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLR 226
Query: 229 RMQVDDLNISGIIA-AVVVVALVISVCGLGVCYAQRKGYFSKETSFQK 275
V N +G+IA A++ L +++ GL + ++K +E ++K
Sbjct: 227 LNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKK---RREEKYEK 271
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 69.7 bits (169), Expect = 3e-12
Identities = 52/165 (31%), Positives = 76/165 (46%), Gaps = 14/165 (8%)
Query: 93 NIRIKNVTRSDAGKYRCEVS-APSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+I I N SD G Y+C V+ P G+N+ L VLV P+ P C++ S G+ V
Sbjct: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNI--GVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C +EG P P Y W K L+N + + T + GT+ +S L +G
Sbjct: 162 ILLCSSEEGIPRPTYLWEK-----LDN----TLKLPPTATQDQVQGTVTIRNISALSSGL 212
Query: 212 YSCEARNSVGYRRC--PGKRMQVDDLNISGIIAAVVVVALVISVC 254
Y C A N++G C + + NI I A+ A++I C
Sbjct: 213 YQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFC 257
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 69.7 bits (169), Expect = 3e-12
Identities = 52/165 (31%), Positives = 76/165 (46%), Gaps = 14/165 (8%)
Query: 93 NIRIKNVTRSDAGKYRCEVS-APSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+I I N SD G Y+C V+ P G+N+ L VLV P+ P C++ S G+ V
Sbjct: 103 SIFINNTQLSDTGTYQCLVNNLPDIGGRNI--GVTGLTVLVPPSAPHCQIQGSQDIGSDV 160
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C +EG P P Y W K L+N + + T + GT+ +S L +G
Sbjct: 161 ILLCSSEEGIPRPTYLWEK-----LDN----TLKLPPTATQDQVQGTVTIRNISALSSGL 211
Query: 212 YSCEARNSVGYRRC--PGKRMQVDDLNISGIIAAVVVVALVISVC 254
Y C A N++G C + + NI I A+ A++I C
Sbjct: 212 YQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFC 256
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 67.4 bits (163), Expect = 1e-11
Identities = 44/126 (34%), Positives = 58/126 (46%), Gaps = 12/126 (9%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRC 155
I N+ SD G Y CE A ++ G+ E TVT+ LVAP + ++ + G + L C
Sbjct: 854 ILNLWASDKGTYICE--AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPC 911
Query: 156 QDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
GNP PE W K+ LL+NP Y G+L V D GEY+C
Sbjct: 912 TLLAGNPIPERRWIKNSAMLLQNP----------YITVRSDGSLHIERVQLQDGGEYTCV 961
Query: 216 ARNSVG 221
A N G
Sbjct: 962 ASNVAG 967
Score = 59.3 bits (142), Expect = 4e-09
Identities = 50/164 (30%), Positives = 68/164 (41%), Gaps = 28/164 (17%)
Query: 61 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFN--IRIKNVTRSDAGKYRC-EVSAPSEQ 117
L W K G VS F N +++ + + + SD G+Y C V+A E+
Sbjct: 2043 LTWLKDGSPVS----------SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEK 2092
Query: 118 GQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLE 177
++++ L V V P + E S L VEL CQ + P P TW KDG LL+
Sbjct: 2093 QRDID-----LRVYVPPNIMGEEQNVSVLISQAVELLCQS-DAIPPPTLTWLKDGHPLLK 2146
Query: 178 NPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P L S L+ DTG Y+CEA N G
Sbjct: 2147 KPGLSISENRS---------VLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 52.4 bits (124), Expect = 5e-07
Identities = 51/174 (29%), Positives = 78/174 (44%), Gaps = 28/174 (16%)
Query: 60 RLEWKKLGRSVSFVYY---QQTLQGD----FKNRAEMIDFNIRIKNVTRSDAGKYRCEVS 112
+LE K G V + + + L G F NR ++ID I++ SDAG Y+C V+
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID----IESAQISDAGIYKC-VA 1993
Query: 113 APSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDG 172
S L +L+V VAP++ + + V L C+ + G PAP TW KD
Sbjct: 1994 INSAGATEL---FYSLQVHVAPSISGSNNMVAVVVNNPVRLECEAR-GIPAPSLTWLKD- 2048
Query: 173 IRLLENPRLGSQSTNSSYTMNTKTG--TLQFNTVSKLDTGEYSCEARNSVGYRR 224
GS ++ S + +G L + DTG Y+C A N+ G ++
Sbjct: 2049 ---------GSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ 2093
Score = 51.2 bits (121), Expect = 1e-06
Identities = 47/189 (24%), Positives = 84/189 (44%), Gaps = 31/189 (16%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFN--IR 95
V+ V ++ L C+ K T + W K G+ + GD E++D +
Sbjct: 1463 VSVVLNRDVALECQV-KGTPFPDIHWFKDGKPLFL--------GD--PNVELLDRGQVLH 1511
Query: 96 IKNVTRSDAGKYRCEVS-APSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVVE 152
+KN R+D G+Y+C VS A +Q ++++ L + + P++ V + S L ++++
Sbjct: 1512 LKNARRNDKGRYQCTVSNAAGKQAKDIK-----LTIYIPPSIKGGNVTTDISVLINSLIK 1566
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C+ + G P P TW+KDG ++ ++S K L D+ Y
Sbjct: 1567 LECETR-GLPMPAITWYKDGQPIM---------SSSQALYIDKGQYLHIPRAQVSDSATY 1616
Query: 213 SCEARNSVG 221
+C N G
Sbjct: 1617 TCHVANVAG 1625
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/166 (28%), Positives = 69/166 (41%), Gaps = 24/166 (14%)
Query: 56 TVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPS 115
T S + W+K G +V+ +N A + ++I R DAG Y C P+
Sbjct: 4014 TPSPFITWQKEGINVNT---------SGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 116 EQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRL 175
G L + + L V V P + + L C+ +G P P+ TW KDG +
Sbjct: 4065 --GTALGK--IKLNVQVPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDGRAI 4119
Query: 176 LENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
+E+ R Q SS G+LQ V D G Y+C A N G
Sbjct: 4120 VESIR---QRVLSS-------GSLQIAFVQPGDAGHYTCMAANVAG 4155
Score = 50.8 bits (120), Expect = 1e-06
Identities = 39/134 (29%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D ++ I+ V D G+Y C S + G N + +V + VL P + + S + G
Sbjct: 942 DGSLHIERVQLQDGGEYTCVAS--NVAGTNNKTTSVVVHVL--PTIQHGQQILSTIEGIP 997
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C+ GNP P W K G + ST+S+ G+L + ++G
Sbjct: 998 VTLPCK-ASGNPKPSVIWSKKGELI---------STSSAKFSAGADGSLYVVSPGGEESG 1047
Query: 211 EYSCEARNSVGYRR 224
EY C A N+ GY +
Sbjct: 1048 EYVCTATNTAGYAK 1061
Score = 50.8 bits (120), Expect = 1e-06
Identities = 39/130 (30%), Positives = 53/130 (40%), Gaps = 14/130 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
++I SD+G Y C S + Q L + V P+V E+PS S L G V
Sbjct: 3209 LQIARSQHSDSGNYTCIASNMEGKAQKY----YFLSIQVPPSVAGAEIPSDVSVLLGENV 3264
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
EL C + G P P W KDG + + ++ TL DTG+
Sbjct: 3265 ELVC-NANGIPTPLIQWLKDGKPI-------ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 212 YSCEARNSVG 221
Y+C A N G
Sbjct: 3317 YTCVATNPAG 3326
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/164 (27%), Positives = 65/164 (39%), Gaps = 25/164 (15%)
Query: 60 RLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQ 119
++ W K GR + QTL G E++ RI D G+Y C S+P+
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGG-----GEVL----RISTAQVEDTGRYTCLASSPAGD-- 3607
Query: 120 NLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLE 177
++ + V V P + + P + L V L C+ + P P TW ++G RL
Sbjct: 3608 --DDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERLQA 3664
Query: 178 NPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
PR+ S LQ N DT Y+C A N G
Sbjct: 3665 TPRVRILSGGR---------YLQINNADLGDTANYTCVASNIAG 3699
Score = 50.1 bits (118), Expect = 2e-06
Identities = 53/211 (25%), Positives = 86/211 (40%), Gaps = 36/211 (17%)
Query: 20 ALGYHKAYGFSAPKDQQVVTAVEYQE---------AILACKTPKKTVSSRLEWKKLGRSV 70
++G+ KA GF K+ V +Y AIL C+ K + ++W + G +
Sbjct: 4333 SVGFVKAIGFVYVKEPPVFKG-DYPSNWIEPLGGNAILNCEV-KGDPTPTIQWNRKGVDI 4390
Query: 71 SFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEV 130
+ + L ++ I DAG Y C A +E G + E +++L +
Sbjct: 4391 EISHRIRQLGNG----------SLAIYGTVNEDAGDYTCV--ATNEAG--VVERSMSLTL 4436
Query: 131 LVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSY 190
P + V + +G + L CQ G P P TW + G + + R+ S NS Y
Sbjct: 4437 QSPPIITLEPVETVINAGGKIILNCQ-ATGEPQPTITWSRQGHSISWDDRVNVLSNNSLY 4495
Query: 191 TMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
+ + K DT E+ C ARN +G
Sbjct: 4496 IADAQ----------KEDTSEFECVARNLMG 4516
Score = 49.7 bits (117), Expect = 3e-06
Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 24/184 (13%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
VT + A+L C V L W++ R V + + + ++ +K
Sbjct: 529 VTVTPGERAVLTCLIIS-AVDYNLTWQRNDRDVRLAEPARI--------RTLANLSLELK 579
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
+V +DAG+Y C VS SE G + +V L V P V S G+ V + C
Sbjct: 580 SVKFNDAGEYHCMVS--SEGGSSAA--SVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCS- 634
Query: 158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
G P P+ W + + ++ + R Y M T GTL + D G Y C A
Sbjct: 635 ATGYPKPKIAWTVNDMFIVGSHR---------YRM-TSDGTLFIKNAAPKDAGIYGCLAS 684
Query: 218 NSVG 221
NS G
Sbjct: 685 NSAG 688
Score = 48.9 bits (115), Expect = 5e-06
Identities = 49/195 (25%), Positives = 77/195 (39%), Gaps = 40/195 (20%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
++ VE L C+ + S + W K G VS + L G +R+
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPS-ITWFKDGWPVSLSNSVRILSGGRM---------LRLM 2445
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
T DAG+Y C V + + E L VLV P + T+ +++ ++
Sbjct: 2446 QTTMEDAGQYTCVVRNAAGE----ERKIFGLSVLVPPHIVG--------ENTLEDVKVKE 2493
Query: 158 KE---------GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
K+ GNP PE TW KDG L E + ++ + + LQ V
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQE---------DEAHHIISGGRFLQITNVQVPH 2544
Query: 209 TGEYSCEARNSVGYR 223
TG Y+C A + G++
Sbjct: 2545 TGRYTCLASSPAGHK 2559
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 16/138 (11%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D + IKN DAG Y C S ++ TL + AP + + G +
Sbjct: 663 DGTLFIKNAAPKDAGIYGCLAS----NSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDI 718
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
+ C+ G P P+ WFK + L + L ++ G L+ LD G
Sbjct: 719 TVMECKTS-GIPPPQVKWFKGDLELRPSTFL---------IIDPLLGLLKIQETQDLDAG 768
Query: 211 EYSCEARNSVGYRRCPGK 228
+Y+C A N G R GK
Sbjct: 769 DYTCVAINEAG--RATGK 784
Score = 45.4 bits (106), Expect = 6e-05
Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 16/128 (12%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVVEL 153
I +VT D G+Y C A +E G E L+V V P + E + S L + L
Sbjct: 1325 IASVTPYDNGEYICV--AVNEAGTT--ERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNL 1380
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C+ EG P+P W+KD +++ E+ + Q+ N+ + T + D G YS
Sbjct: 1381 FCE-VEGTPSPIIMWYKDNVQVTESSTI--QTVNNGKILKLFRATPE-------DAGRYS 1430
Query: 214 CEARNSVG 221
C+A N G
Sbjct: 1431 CKAINIAG 1438
Score = 43.5 bits (101), Expect = 2e-04
Identities = 49/189 (25%), Positives = 70/189 (37%), Gaps = 29/189 (15%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
V E Q L C+ V + W K G Q LQ D + ++I
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPE-ITWHKDG---------QPLQEDEAHHIISGGRFLQIT 2538
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV-----E 152
NV G+Y C S+P+ + + +L V V+P + + TV+
Sbjct: 2539 NVQVPHTGRYTCLASSPAGH----KSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTS 2594
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C+ PA TWFKDG L +N + + TLQ + + G Y
Sbjct: 2595 LVCEAYSYPPAT-ITWFKDGTPL---------ESNRNIRILPGGRTLQILNAQEDNAGRY 2644
Query: 213 SCEARNSVG 221
SC A N G
Sbjct: 2645 SCVATNEAG 2653
Score = 43.1 bits (100), Expect = 3e-04
Identities = 38/133 (28%), Positives = 54/133 (40%), Gaps = 18/133 (13%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRC 155
++NV D+G Y C + + + + TV+L V V P S G + L C
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGE----DTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSC 4281
Query: 156 QDKEGNPAPEYTW-FKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSC 214
+ G P P+ TW F + I + S L VSK D+G Y C
Sbjct: 4282 K-ATGIPLPKLTWTFNNNIIPAHFDSVNGHSE------------LVIERVSKEDSGTYVC 4328
Query: 215 EARNSVGYRRCPG 227
A NSVG+ + G
Sbjct: 4329 TAENSVGFVKAIG 4341
Score = 42.4 bits (98), Expect = 5e-04
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 16/155 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I+ DAG Y C A +E G+ + +TL+V P S G+ V L
Sbjct: 757 LKIQETQDLDAGDYTCV--AINEAGRATGK--ITLDVGSPPVFIQEPADVSMEIGSNVTL 812
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C +G P P W R L+N + S+ + S +TG L + D G Y
Sbjct: 813 PCY-VQGYPEPTIKW-----RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 214 CEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVA 248
CEA N GK + ++G++A ++ ++
Sbjct: 867 CEAENQF------GKIQSETTVTVTGLVAPLIGIS 895
Score = 42.0 bits (97), Expect = 7e-04
Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
+++I SD+G Y C + N+ + V L V V P + G V+
Sbjct: 1134 SMKITETRTSDSGMYLC---VATNIAGNVTQ-AVKLNVHVPPKIQRGPKHLKVQVGQRVD 1189
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+ C + +G P P TW K G +L + + ++ GTL + + D G Y
Sbjct: 1190 IPC-NAQGTPLPVITWSKGGSTML---------VDGEHHVSNPDGTLSIDQATPSDAGIY 1239
Query: 213 SCEARNSVG 221
+C A N G
Sbjct: 1240 TCVATNIAG 1248
Score = 42.0 bits (97), Expect = 7e-04
Identities = 35/134 (26%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV-PSCEVPS--SALSGTV 150
+++KN+ SD G+Y C + + + L V P++ + P S +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVA----GMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C+ G P P TWFKDG + S ++S + + L+ + D G
Sbjct: 2404 VSLTCE-ASGIPLPSITWFKDGWPV---------SLSNSVRILSGGRMLRLMQTTMEDAG 2453
Query: 211 EYSCEARNSVGYRR 224
+Y+C RN+ G R
Sbjct: 2454 QYTCVVRNAAGEER 2467
Score = 42.0 bits (97), Expect = 7e-04
Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 18/124 (14%)
Query: 102 SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL----SGTVVELRCQD 157
SD G+Y C A ++ G++ ++ ++T V V P++ + S ++ GT V L C+
Sbjct: 3028 SDGGEYTC--IAINQAGESKKKFSLT--VYVPPSIKDHDSESLSVVNVREGTSVSLECES 3083
Query: 158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
P P TW+K+G R+ ++ST+ + + L DTG+Y C A
Sbjct: 3084 N-AVPPPVITWYKNG-------RMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAI 3133
Query: 218 NSVG 221
N G
Sbjct: 3134 NVAG 3137
Score = 42.0 bits (97), Expect = 7e-04
Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+++ D+GKY C S +E G+ + L+VL P + E S + +
Sbjct: 3491 LQLLKAETEDSGKYTCIAS--NEAGEVSKH--FILKVLEPPHINGSEEHEEISVIVNNPL 3546
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
EL C G PAP+ TW KDG L + ++ + L+ +T DTG
Sbjct: 3547 ELTCI-ASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE---------VLRISTAQVEDTGR 3596
Query: 212 YSCEARNSVG 221
Y+C A + G
Sbjct: 3597 YTCLASSPAG 3606
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 18/149 (12%)
Query: 78 TLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVP 137
T+ D ++ D + I T SDAG Y C + + +E +TL V P V
Sbjct: 1210 TMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA----GTDETEITLHVQEPPTVE 1265
Query: 138 SCEVP-----SSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTM 192
E P ++ +E C K G P P W +G L G + S
Sbjct: 1266 DLEPPYNTTFQERVANQRIEFPCPAK-GTPKPTIKWLHNGREL-----TGREPGISILED 1319
Query: 193 NTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
T L +V+ D GEY C A N G
Sbjct: 1320 GT---LLVIASVTPYDNGEYICVAVNEAG 1345
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 25/190 (13%)
Query: 32 PKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
P + V+ V+ A A PK +++ W+K G ++ Q + + +
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSIN----WRKNGHLLNVDQNQNSYR-------LLSS 3858
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
++ I + + D Y C V+ G ++ TV L V V P++
Sbjct: 3859 GSLVIISPSVDDTATYECTVT----NGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPA 3914
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
+ C G P P W K+GIRLL PR SS G ++ G
Sbjct: 3915 VITCT-ASGVPFPSIHWTKNGIRLL--PRGDGYRILSS-------GAIEILATQLNHAGR 3964
Query: 212 YSCEARNSVG 221
Y+C ARN+ G
Sbjct: 3965 YTCVARNAAG 3974
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 14/131 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I N D Y C S + G+ E +T+ V P + L L
Sbjct: 3677 LQINNADLGDTANYTCVAS--NIAGKTTREFILTVNV--PPNIKGGPQSLVILLNKSTVL 3732
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C EG P P TW KDG L N ++ Y++ + G L + DTG Y
Sbjct: 3733 ECI-AEGVPTPRITWRKDGAVLAGN--------HARYSI-LENGFLHIQSAHVTDTGRYL 3782
Query: 214 CEARNSVGYRR 224
C A N+ G R
Sbjct: 3783 CMATNAAGTDR 3793
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 20/133 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQN-LEEDTVTLEVLVAPAVPSC--EVPS--SALSG 148
++I DAG+Y C A +E G++ L+ D + VLV P + ++P + L
Sbjct: 2833 LQIPRAKVEDAGRYTCV--AVNEAGEDSLQYD---VRVLVPPIIKGANSDLPEEVTVLVN 2887
Query: 149 TVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
+ C G+PAP +W KDG LLE+ + + N + LQ D
Sbjct: 2888 KSALIECLSS-GSPAPRNSWQKDGQPLLED-------DHHKFLSNGR--ILQILNTQITD 2937
Query: 209 TGEYSCEARNSVG 221
G Y C A N+ G
Sbjct: 2938 IGRYVCVAENTAG 2950
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 20/135 (14%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I N +AG+Y C A +E G+ ++ V +V + P + ++ LS V++
Sbjct: 2631 LQILNAQEDNAGRYSCV--ATNEAGEMIKHYEV--KVYIPPIINKGDLWGPGLSPKEVKI 2686
Query: 154 RCQ-------DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
+ + P+ +W+KDG L + + + TLQ
Sbjct: 2687 KVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH---------TLQIKEAQI 2737
Query: 207 LDTGEYSCEARNSVG 221
DTG Y+C A N G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 39.3 bits (90), Expect = 0.004
Identities = 33/130 (25%), Positives = 51/130 (39%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
IRI SD Y C S + ++ L+V P + + + L G+
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRA----GVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSST 3453
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
+ C +G PAP W +DG L ++ T++T LQ D+G+
Sbjct: 3454 SMACIT-DGTPAPSMAWLRDGQPL---------GLDAHLTVSTHGMVLQLLKAETEDSGK 3503
Query: 212 YSCEARNSVG 221
Y+C A N G
Sbjct: 3504 YTCIASNEAG 3513
Score = 38.9 bits (89), Expect = 0.006
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVP---SCEVPSSALSGTV 150
+ I SD+ Y C V+ + E + ++V V P + + + +
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVA----GTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHS 1658
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
+ L C+ GNP+P TW KDG+ + N + ++ L+ + ++D G
Sbjct: 1659 LTLECK-AAGNPSPILTWLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRG 1708
Query: 211 EYSCEARNSVG 221
+Y C A + G
Sbjct: 1709 QYICVATSVAG 1719
Score = 38.9 bits (89), Expect = 0.006
Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVP-SCEVPSSAL--SGTV 150
++I +SDA Y C S + + L+V + P + S P+ + G
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKK----EYNLQVYIRPTITNSGSHPTEIIVTRGKS 2309
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
+ L C+ +G P P TW KDG L++ G + + + LQ + DTG
Sbjct: 2310 ISLECE-VQGIPPPTVTWMKDGHPLIK--AKGVEILDEGH-------ILQLKNIHVSDTG 2359
Query: 211 EYSCEARNSVG 221
Y C A N G
Sbjct: 2360 RYVCVAVNVAG 2370
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/161 (27%), Positives = 64/161 (39%), Gaps = 24/161 (14%)
Query: 61 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN 120
+ W K GR++ Q+ L +++I V DAG Y C A + G +
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSG----------SLQIAFVQPGDAGHYTC--MAANVAGSS 4157
Query: 121 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR 180
+ L V V P + S E + + L C +G P P W KD + LL N
Sbjct: 4158 --STSTKLTVHVPPRIRSTEGHYTVNENSQAILPCV-ADGIPTPAINWKKDNV-LLAN-- 4211
Query: 181 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
L + T Y G L V D+G Y+C A N+ G
Sbjct: 4212 LLGKYTAEPY------GELILENVVLEDSGFYTCVANNAAG 4246
Score = 37.7 bits (86), Expect = 0.012
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 29/194 (14%)
Query: 30 SAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEM 89
+ P ++QVV A L CK S L W K G V + + R E
Sbjct: 1646 ATPLNKQVVIA---HSLTLECKAAGNP-SPILTWLKDGVPV---------KANDNIRIEA 1692
Query: 90 IDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSS--ALS 147
+ I + D G+Y C ++ + + +E ++VLV PA+ + S +
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGE----KEIKYEVDVLVPPAIEGGDETSYFIVMV 1748
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
++EL C G+P P W KDG +L + +N + + VS
Sbjct: 1749 NNLLELDCH-VTGSPPPTIMWLKDG-------QLIDERDGFKILLNGRKLVIAQAQVS-- 1798
Query: 208 DTGEYSCEARNSVG 221
+TG Y C A N+ G
Sbjct: 1799 NTGLYRCMAANTAG 1812
Score = 37.4 bits (85), Expect = 0.016
Identities = 30/131 (22%), Positives = 49/131 (37%), Gaps = 17/131 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS---GTV 150
+ I SD GKY C + P+ + E+ L V V P + + + L T
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE----EDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
+ + C+ G P P+ W K+G+ L +S + ++ D
Sbjct: 3360 INIECR-ATGTPPPQINWLKNGLPL---------PLSSHIRLLAAGQVIRIVRAQVSDVA 3409
Query: 211 EYSCEARNSVG 221
Y+C A N G
Sbjct: 3410 VYTCVASNRAG 3420
Score = 37.4 bits (85), Expect = 0.016
Identities = 32/128 (25%), Positives = 48/128 (37%), Gaps = 14/128 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
I I + AG+Y C + VTL V P + + + L
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHR----HVTLHVHEPPVIQPQPSELHVILNNPILL 4007
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C+ G P+P TW K+GI + +T+ +G LQ + + D G Y
Sbjct: 4008 PCE-ATGTPSPFITWQKEGINV---------NTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 214 CEARNSVG 221
C A+N G
Sbjct: 4058 CVAQNPAG 4065
Score = 35.0 bits (79), Expect = 0.080
Identities = 49/198 (24%), Positives = 76/198 (38%), Gaps = 38/198 (19%)
Query: 35 QQVVTAVEYQEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
QQ+++ +E L CK PK +V W K G +S T F A D
Sbjct: 987 QQILSTIEGIPVTLPCKASGNPKPSVI----WSKKGELIS------TSSAKFSAGA---D 1033
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCE--------VPS 143
++ + + ++G+Y C + + + V L V V P V + V
Sbjct: 1034 GSLYVVSPGGEESGEYVCTATNTAGYAKR----KVQLTVYVRPRVFGDQRGLSQDKPVEI 1089
Query: 144 SALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNT 203
S L+G V L C+ K P P TW K E + S ++ +G+++
Sbjct: 1090 SVLAGEEVTLPCEVKS-LPPPIITWAK------ETQLISPFSPRHTFL---PSGSMKITE 1139
Query: 204 VSKLDTGEYSCEARNSVG 221
D+G Y C A N G
Sbjct: 1140 TRTSDSGMYLCVATNIAG 1157
Score = 34.7 bits (78), Expect = 0.10
Identities = 39/126 (30%), Positives = 51/126 (40%), Gaps = 24/126 (19%)
Query: 102 SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV------ELRC 155
S+ G YRC A + G + +E VT+ V + SS LS VV L+C
Sbjct: 1798 SNTGLYRC--MAANTAGDHKKEFEVTVHVPPT-------IKSSGLSERVVVKYKPVALQC 1848
Query: 156 QDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
G P P TW KD + N G+ SS + LQ D G Y+C
Sbjct: 1849 I-ANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRV------LQIAKTLLEDAGRYTCV 1899
Query: 216 ARNSVG 221
A N+ G
Sbjct: 1900 ATNAAG 1905
Score = 33.5 bits (75), Expect = 0.23
Identities = 43/177 (24%), Positives = 63/177 (35%), Gaps = 37/177 (20%)
Query: 58 SSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQ 117
S+ L W K G Q L+ D ++IK SD G+Y C S + +
Sbjct: 2703 SASLSWYKDG---------QPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGE 2753
Query: 118 GQNLEEDTVTLEVLVAPAVPSC-EVPSSALSG-----------TVVELRCQDKEGNPAPE 165
+E + + V P+ E+ + +G + L C+ P P
Sbjct: 2754 ----DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAA-PPPT 2808
Query: 166 YTWFKDGIRLLENPRLGSQSTNSSYTMNTKTG-TLQFNTVSKLDTGEYSCEARNSVG 221
TW+KDG L T+S + G LQ D G Y+C A N G
Sbjct: 2809 LTWYKDGHPL----------TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 33.5 bits (75), Expect = 0.23
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 27/186 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
VT + + A++ C + + + R W+K G Q L D ++ ++I
Sbjct: 2882 VTVLVNKSALIECLS-SGSPAPRNSWQKDG---------QPLLEDDHHKFLSNGRILQIL 2931
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV--PSCEVPSSALSGTVVELRC 155
N +D G+Y C +E + L V V P+V P E + + + L C
Sbjct: 2932 NTQITDIGRYVCV----AENTAGSAKKYFNLNVHVPPSVIGPKSE-NLTVVVNNFISLTC 2986
Query: 156 QDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
+ G P P+ +W K+ E P N++ + TLQ D GEY+C
Sbjct: 2987 E-VSGFPPPDLSWLKN-----EQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCI 3036
Query: 216 ARNSVG 221
A N G
Sbjct: 3037 AINQAG 3042
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 65.1 bits (157), Expect = 7e-11
Identities = 52/183 (28%), Positives = 78/183 (42%), Gaps = 16/183 (8%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+++ +V SD G Y C+V+ P + N + L VLV P+ P C G L
Sbjct: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTN-GLGLINLTVLVPPSNPLCSQSGQTSVGGSTAL 164
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNS--SYTMNTKTGTLQFNTVSKLDTGE 211
RC EG P P Y W RLG+ T S S + +G L +S +G
Sbjct: 165 RCSSSEGAPKPVYNWV----------RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGT 214
Query: 212 YSCEARNSVGYRRCPGKRMQVDDL--NISGIIAAVVVVALVISVCGLG-VCYAQRKGYFS 268
Y C A N +G C + ++G + V++ L++SV V + + +G
Sbjct: 215 YRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKP 274
Query: 269 KET 271
KET
Sbjct: 275 KET 277
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 62.0 bits (149), Expect = 6e-10
Identities = 43/128 (33%), Positives = 64/128 (50%), Gaps = 12/128 (9%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ I N T+ DAG+Y CE+ +E G+++ V+ L P + P A G V L
Sbjct: 6043 LEILNSTKRDAGQYSCEIE--NEAGRDVCGALVS--TLEPPYFVTELEPLEAAVGDSVSL 6098
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
+CQ G P +W+K +L P + TN+ TL FN V+ D+GEY+
Sbjct: 6099 QCQ-VAGTPEITVSWYKGDTKLRPTPEYRTYFTNN-------VATLVFNKVNINDSGEYT 6150
Query: 214 CEARNSVG 221
C+A NS+G
Sbjct: 6151 CKAENSIG 6158
Score = 52.8 bits (125), Expect = 4e-07
Identities = 39/134 (29%), Positives = 63/134 (47%), Gaps = 13/134 (9%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPA-VPSCEVPSSALSGTVV 151
++RI V + D+G+Y C+ A ++ G+++ + L V P V E A G +
Sbjct: 6327 HLRILKVGKGDSGQYTCQ--ATNDVGKDM--CSAQLSVKEPPKFVKKLEASKVAKQGESI 6382
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
+L C+ G+P + +WF++ L E+ + NS L N S D+G+
Sbjct: 6383 QLECKIS-GSPEIKVSWFRNDSELHESWKYNMSFINS-------VALLTINEASAEDSGD 6434
Query: 212 YSCEARNSVGYRRC 225
Y CEA N VG C
Sbjct: 6435 YICEAHNGVGDASC 6448
Score = 51.2 bits (121), Expect = 1e-06
Identities = 54/190 (28%), Positives = 80/190 (42%), Gaps = 19/190 (10%)
Query: 42 EYQEAILACKTPKKTVSSRLEWKKLGR-SVSFVYY--QQTLQGDFKNRAEMIDFN--IRI 96
++ + + A K K SSRLE K G + V++ + L K R ID I++
Sbjct: 5424 KFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQM 5483
Query: 97 KNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS-SALSGTVVELRC 155
N++ D+G + CE P+ T ++ P V S P L V L C
Sbjct: 5484 NNLSTEDSGDFICEAQNPAGS-----TSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLEC 5538
Query: 156 QDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
+ G P E W+KD +L + + S N +T L +T D GEY C+
Sbjct: 5539 E-LSGTPPFEVVWYKDKRQLRSSKKYKIASKN----FHTSIHILNVDTS---DIGEYHCK 5590
Query: 216 ARNSVGYRRC 225
A+N VG C
Sbjct: 5591 AQNEVGSDTC 5600
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/124 (34%), Positives = 57/124 (45%), Gaps = 13/124 (10%)
Query: 103 DAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSA-LSGTVVELRCQDKEGN 161
D+G Y C +A +E G + TVT V P+ PS L G L C+ K G+
Sbjct: 3710 DSGTYVC--TASNEAGSSSCSATVT--VREPPSFVKKVDPSYLMLPGESARLHCKLK-GS 3764
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P + TWFK+ N L +T Y +N++ L V D+G YSCEA N VG
Sbjct: 3765 PVIQVTWFKN------NKELSESNTVRMYFVNSEA-ILDITDVKVEDSGSYSCEAVNDVG 3817
Query: 222 YRRC 225
C
Sbjct: 3818 SDSC 3821
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 18/169 (10%)
Query: 65 KLGRS--VSFVYYQQT--LQGDFKNRAEMIDFN--IRIKNVTRSDAGKYRCEVSAPSEQG 118
K+G S + ++Y+ +Q K R +D + + N++ D+G Y CE +
Sbjct: 7328 KIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCE----AHNA 7383
Query: 119 QNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLEN 178
+ +L+V P P L G V L C+ +G P +W+KD L
Sbjct: 7384 AGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECE-LQGTPPFHVSWYKDKRELRSG 7442
Query: 179 PRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPG 227
+ S N ++ V D GEY C+A N VG C G
Sbjct: 7443 KKYKIMSENF-------LTSIHILNVDAADIGEYQCKATNDVGSDTCVG 7484
Score = 49.7 bits (117), Expect = 3e-06
Identities = 38/135 (28%), Positives = 61/135 (45%), Gaps = 15/135 (11%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEV---LVAPAVPSCEVPSSALSGTV 150
++I NV SD+G Y EV P + + T +L+V V P+ ++ LSG+
Sbjct: 7643 LKIINVAPSDSGVYSFEVQNPVGK----DSCTASLQVSDRTVPPSFTRKLKETNGLSGSS 7698
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V + C+ G+P +WF +G + S T+ T L N + + D+G
Sbjct: 7699 VVMECK-VYGSPPISVSWFHEGNEI-------SSGRKYQTTLTDNTCALTVNMLEESDSG 7750
Query: 211 EYSCEARNSVGYRRC 225
+Y+C A N G C
Sbjct: 7751 DYTCIATNMAGSDEC 7765
Score = 49.3 bits (116), Expect = 4e-06
Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 11/143 (7%)
Query: 83 FKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP 142
FK ++ D ++ I N+ SD G+Y C+ A +E G + +V + P
Sbjct: 6504 FKITSKHFDTSLHILNLEASDVGEYHCK--ATNEVGSDTCSCSVKFKE--PPRFVKKLSD 6559
Query: 143 SSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFN 202
+S L G VELR EG W KD ++ S++T S+ N TLQ
Sbjct: 6560 TSTLIGDAVELRAI-VEGFQPISVVWLKDRGEVIRE----SENTRISFIDNI--ATLQLG 6612
Query: 203 TVSKLDTGEYSCEARNSVGYRRC 225
+ ++G+Y C+ +N G R C
Sbjct: 6613 SPEASNSGKYICQIKNDAGMREC 6635
Score = 48.9 bits (115), Expect = 5e-06
Identities = 30/135 (22%), Positives = 64/135 (47%), Gaps = 11/135 (8%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVT-LEVLVAPAVPSCEVPSSALSGTVVE 152
++I + + D+G+Y EV ++ G++ + + L++++ P+ ++ G+ ++
Sbjct: 4636 LKIISTEKKDSGEYTFEVQ--NDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFID 4693
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C +P WFKD + S S ++ + T L+ + + D+G Y
Sbjct: 4694 LECIVAGSHPI-SIQWFKDDQEI-------SASEKYKFSFHDNTAFLEISQLEGTDSGTY 4745
Query: 213 SCEARNSVGYRRCPG 227
+C A N G+ +C G
Sbjct: 4746 TCSATNKAGHNQCSG 4760
Score = 48.9 bits (115), Expect = 5e-06
Identities = 36/128 (28%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ I + T DAG+Y C + E + + + +L P P G L
Sbjct: 7925 LEIPSSTVEDAGQYNCYI----ENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASL 7980
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
+CQ G P +W+K +L +T TL FN V D+GEY
Sbjct: 7981 QCQ-LAGTPEIGVSWYKGDTKL-------RPTTTYKMHFRNNVATLVFNQVDINDSGEYI 8032
Query: 214 CEARNSVG 221
C+A NSVG
Sbjct: 8033 CKAENSVG 8040
Score = 48.1 bits (113), Expect = 9e-06
Identities = 39/128 (30%), Positives = 57/128 (44%), Gaps = 12/128 (9%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ I T D +Y C + +E GQ++ E V+ VL P A+ G L
Sbjct: 6984 LEILESTIEDYAQYSCLIE--NEAGQDICEALVS--VLEPPYFIEPLEHVEAVIGEPATL 7039
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
+C+ +G P +W+K+ +L P Q N+ +L N V D GEYS
Sbjct: 7040 QCK-VDGTPEIRISWYKEHTKLRSAPAYKMQFKNN-------VASLVINKVDHSDVGEYS 7091
Query: 214 CEARNSVG 221
C+A NSVG
Sbjct: 7092 CKADNSVG 7099
Score = 48.1 bits (113), Expect = 9e-06
Identities = 40/170 (23%), Positives = 77/170 (45%), Gaps = 16/170 (9%)
Query: 58 SSRLEWKKLG-RSVSFVYYQQTLQGDFKNRAEMIDFN----IRIKNVTRSDAGKYRCEVS 112
S +LE + G + ++ +Y+ ++ + E+ N ++++ +DAG Y C+VS
Sbjct: 8266 SFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVS 8325
Query: 113 APSEQGQNLEEDTVTLEVLVAPAVPSCEV-PSSALSGTVVELRCQDKEGNPAPEYTWFKD 171
++ G L ++ ++ P V + P + G V+L C + P W K
Sbjct: 8326 --NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPI-RIQWLKA 8382
Query: 172 GIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
G + + R S++ + T L+ V+K D+G+Y C+A N G
Sbjct: 8383 GREIKPSDRC-------SFSFASGTAVLELRDVAKADSGDYVCKASNVAG 8425
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 11/143 (7%)
Query: 83 FKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP 142
+K +E +I I NV +D G+Y+C+ A ++ G + ++ L+ P
Sbjct: 7445 YKIMSENFLTSIHILNVDAADIGEYQCK--ATNDVGSDTCVGSIALKA--PPRFVKKLSD 7500
Query: 143 SSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFN 202
S + G V+L+ + P WFKD ++ +S N + + TLQF+
Sbjct: 7501 ISTVVGKEVQLQTTIEGAEPI-SVVWFKDKGEIVR------ESDNIWISYSENIATLQFS 7553
Query: 203 TVSKLDTGEYSCEARNSVGYRRC 225
V + G+Y+C+ +N G + C
Sbjct: 7554 RVEPANAGKYTCQIKNDAGMQEC 7576
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/196 (23%), Positives = 79/196 (40%), Gaps = 26/196 (13%)
Query: 33 KDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDF 92
++ + V V+Y + L C+ T + W K R + + + + +R + F
Sbjct: 4959 RELKPVEVVKYSDVELECEVTG-TPPFEVTWLKNNREI-----RSSKKYTLTDRVSV--F 5010
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
N+ I SD G+Y+C VS E + + VA P + + TV++
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSN--------EGGSCSCSTRVALKEPPSFIKKIENTTTVLK 5062
Query: 153 LRCQDKE---GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDT 209
+ G+P TW KD L E+ + +S TLQ +V +
Sbjct: 5063 SSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS-------VATLQIRSVDNGHS 5115
Query: 210 GEYSCEARNSVGYRRC 225
G Y+C+A+N G RC
Sbjct: 5116 GRYTCQAKNESGVERC 5131
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 17/146 (11%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++ V ++AGKY C++ + ++E TL VL + +G L
Sbjct: 7550 LQFSRVEPANAGKYTCQI----KNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTL 7605
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMN--TKTGTLQFNTVSKLDTGE 211
C G P WFKDG L ++++ Y ++ K L+ V+ D+G
Sbjct: 7606 ECT-VAGTPELSTKWFKDGKEL---------TSDNKYKISFFNKVSGLKIINVAPSDSGV 7655
Query: 212 YSCEARNSVGYRRCPGKRMQVDDLNI 237
YS E +N VG C +QV D +
Sbjct: 7656 YSFEVQNPVGKDSCTAS-LQVSDRTV 7680
Score = 47.0 bits (110), Expect = 2e-05
Identities = 35/124 (28%), Positives = 49/124 (39%), Gaps = 12/124 (9%)
Query: 102 SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGN 161
S++GKY C++ + + E + L VL + P + +G L C G
Sbjct: 6617 SNSGKYICQI----KNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECV-VTGT 6671
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P WFKDG L S + T K +L+ D G YS E +NSVG
Sbjct: 6672 PELSAKWFKDGREL-------SADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724
Query: 222 YRRC 225
C
Sbjct: 6725 KSNC 6728
Score = 46.2 bits (108), Expect = 3e-05
Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
Query: 88 EMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS 147
E ++ ++ + V SD+G Y C+VS + G + E A V E
Sbjct: 4257 EALESSLELYLVKTSDSGTYTCKVSNVAG-GVECSANLFVKEP--ATFVEKLEPSQLLKK 4313
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G +L C+ G P + TWF N R +S+ + T L+ V
Sbjct: 4314 GDATQLACK-VTGTPPIKITWFA-------NDREIKESSKHRMSFVESTAVLRLTDVGIE 4365
Query: 208 DTGEYSCEARNSVGYRRC 225
D+GEY CEA+N G C
Sbjct: 4366 DSGEYMCEAQNEAGSDHC 4383
Score = 46.2 bits (108), Expect = 3e-05
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 18/136 (13%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP---SSALSGT 149
++ + N+ D Y C+VS N+ D +L PS V A+ +
Sbjct: 5293 SLEVNNLELEDTANYTCKVS-------NVAGDDACSGILTVKEPPSFLVKPGRQQAIPDS 5345
Query: 150 VVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDT 209
VE + K G P + WFKD + L+ P+ + T L +V T
Sbjct: 5346 TVEFKAILK-GTPPFKIKWFKDDVELVSGPKC-------FIGLEGSTSFLNLYSVDASKT 5397
Query: 210 GEYSCEARNSVGYRRC 225
G+Y+C N VG C
Sbjct: 5398 GQYTCHVTNDVGSDSC 5413
Score = 45.1 bits (105), Expect = 8e-05
Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 28/186 (15%)
Query: 44 QEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSD 103
+ A L CK V ++ W K + +S T++ F N ++D I +V D
Sbjct: 3753 ESARLHCKLKGSPVI-QVTWFKNNKELS---ESNTVRMYFVNSEAILD----ITDVKVED 3804
Query: 104 AGKYRCEVSAPSEQGQNLEEDTVTLEVLVA--PAVPSCEVPSSALSGTVVELRCQDKEGN 161
+G Y CE ++ D+ + E+++ P+ P+ + GT L+C+
Sbjct: 3805 SGSYSCEAV------NDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTG 3858
Query: 162 PAPEYTWFKDG--IRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
P E +WFKD IR + RL SQ + L+ + + D GEY C N
Sbjct: 3859 PF-EISWFKDKKQIRSSKKYRLFSQKS---------LVCLEIFSFNSADVGEYECVVANE 3908
Query: 220 VGYRRC 225
VG C
Sbjct: 3909 VGKCGC 3914
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/174 (24%), Positives = 64/174 (36%), Gaps = 17/174 (9%)
Query: 60 RLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQ 119
R +W K GR + Y+ R+ ++ I D G+Y C+ S +E G
Sbjct: 3486 RFQWFKAGREI----YESD---KCSIRSSKYISSLEILRTQVVDCGEYTCKAS--NEYGS 3536
Query: 120 NLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENP 179
T+T+ P S + G + C G P E W KDG L +P
Sbjct: 3537 VSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICT-VTGTPVIETIWQKDGAALSPSP 3595
Query: 180 RLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVD 233
+ + + T+Q D G YSC+A N G C + + +D
Sbjct: 3596 NWRISDAENKHILELSNLTIQ-------DRGVYSCKASNKFGADICQAELIIID 3642
Score = 44.7 bits (104), Expect = 1e-04
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 18/204 (8%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEED-TVTLEVLVAPAVPSCEVPSSALSGT 149
D + IK + D G C +S E + D T++ E+ APA S + G
Sbjct: 33091 DQTLTIKQASHRDEGILTC-ISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQ 33149
Query: 150 VVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDT 209
V C+ G P+PE WFK+ + + S S+N S + + +L+ S D+
Sbjct: 33150 NVLFTCEIS-GEPSPEIEWFKNNLPI-------SISSNVSISRSRNVYSLEIRNASVSDS 33201
Query: 210 GEYSCEARNSVGYRRCPGKRM---QVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGY 266
G+Y+ +A+N G M V++ + ++ +L S V + K
Sbjct: 33202 GKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK-- 33259
Query: 267 FSKETSFQKSNSSSKATTMSENDF 290
+E SF S SSS A++M+E F
Sbjct: 33260 --QEASF-SSFSSSSASSMTEMKF 33280
Score = 44.3 bits (103), Expect = 1e-04
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 12/133 (9%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
+++I +DAG+Y+C V+ +E G ++ VTL P+ +S+L G
Sbjct: 4449 SLQILKFVAADAGEYQCRVT--NEVGSSICSARVTLRE--PPSFIKKIESTSSLRGGTAA 4504
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+ K P TW KD + E+ N T +L + + G+Y
Sbjct: 4505 FQATLKGSLPIT-VTWLKDSDEITEDD-------NIRMTFENNVASLYLSGIEVKHDGKY 4556
Query: 213 SCEARNSVGYRRC 225
C+A+N G +RC
Sbjct: 4557 VCQAKNDAGIQRC 4569
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 15/127 (11%)
Query: 102 SDAGKYRCEVSAPSEQGQNLEEDTVTL----EVLVAPAVPSCEVPSSAL---SGTVVELR 154
++ +Y + A +E+G + +TVT ++ V P + +P + +G VEL
Sbjct: 29700 NEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELV 29759
Query: 155 CQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSC 214
G P P +WF G +L E+ R+ ++ +TK L + DTGEY+
Sbjct: 29760 IPIA-GRPPPAASWFFAGSKLRESERVTVET-------HTKVAKLTIRETTIRDTGEYTL 29811
Query: 215 EARNSVG 221
E +N G
Sbjct: 29812 ELKNVTG 29818
Score = 43.1 bits (100), Expect = 3e-04
Identities = 50/195 (25%), Positives = 81/195 (41%), Gaps = 31/195 (15%)
Query: 38 VTAVEYQEAILACK---TPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
+T + L CK TP+ +V EW K G+ ++ Q + F N+ ++
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSV----EWYKDGKLLTS---SQKHKFSFYNKIS----SL 5761
Query: 95 RIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAP-AVPSCEVPSSALSGTVVEL 153
RI +V R DAG Y +V N+ + + T V V+ AVP +G V+
Sbjct: 5762 RILSVERQDAGTYTFQVQ------NNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGA 5815
Query: 154 RC--QDKEGNPAP-EYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
C + K +P WF + +++ + + T + TLQ N++ D G
Sbjct: 5816 SCILECKVAGSSPISVAWFHEKTKIVSGAKYQT-------TFSDNVCTLQLNSLDSSDMG 5868
Query: 211 EYSCEARNSVGYRRC 225
Y+C A N G C
Sbjct: 5869 NYTCVAANVAGSDEC 5883
Score = 42.7 bits (99), Expect = 4e-04
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 24/196 (12%)
Query: 32 PKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
P+ V T + + TP+ + +W K GR +S D K+ I+
Sbjct: 6651 PEPMTVTTGNPFALECVVTGTPELSA----KWFKDGRELS---------ADSKHHITFIN 6697
Query: 92 --FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGT 149
+++I SD G Y EV S N + +V P+ +A+ G
Sbjct: 6698 KVASLKIPCAEMSDKGLYSFEVKN-SVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGA 6756
Query: 150 VVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDT 209
V L C+ G+ WF+DG ++ P+ S + + T+N + + DT
Sbjct: 6757 SVVLECR-VSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN-------LSLLEPSDT 6808
Query: 210 GEYSCEARNSVGYRRC 225
G Y+C A N G C
Sbjct: 6809 GIYTCVAANVAGSDEC 6824
Score = 42.7 bits (99), Expect = 4e-04
Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 25/188 (13%)
Query: 38 VTAVEYQEAILACK---TPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
V AV + A L CK TP+ +S E KL + ++ + FKN + N
Sbjct: 7029 VEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAY-------KMQFKNNVASLVIN- 7080
Query: 95 RIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS-SALSGTVVEL 153
V SD G+Y C+ A + G + ++ P + ++ G V
Sbjct: 7081 ---KVDHSDVGEYSCK--ADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAF 7135
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C+ P + +W+KDG+ L ++ L +S+ N TLQ + G+Y+
Sbjct: 7136 ECRINGSEPL-QVSWYKDGVLLKDDANL-----QTSFVHNV--ATLQILQTDQSHIGQYN 7187
Query: 214 CEARNSVG 221
C A N +G
Sbjct: 7188 CSASNPLG 7195
Score = 41.6 bits (96), Expect = 9e-04
Identities = 34/138 (24%), Positives = 54/138 (39%), Gaps = 17/138 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPA---VPSCEVPSSALSGTV 150
+ + +V S G+Y C V+ ++ D+ T +LV V E +G
Sbjct: 5387 LNLYSVDASKTGQYTCHVT------NDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDS 5440
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
L C+ G+P WF++ L S T +Q N +S D+G
Sbjct: 5441 SRLECKIA-GSPEIRVVWFRNEHEL-------PASDKYRMTFIDSVAVIQMNNLSTEDSG 5492
Query: 211 EYSCEARNSVGYRRCPGK 228
++ CEA+N G C K
Sbjct: 5493 DFICEAQNPAGSTSCSTK 5510
Score = 40.4 bits (93), Expect = 0.002
Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 20/174 (11%)
Query: 56 TVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPS 115
T +++W K G+ + Y F+N + RI++V + D+G+Y +V
Sbjct: 5167 TPELKVKWLKDGKQIVPSRY---FSMSFENNVA----SFRIQSVMKQDSGQYTFKVENDF 5219
Query: 116 EQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRL 175
+ + L+ + P+ + G+ + + C+ P WFKDG +
Sbjct: 5220 GSS-SCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ-WFKDGKEI 5277
Query: 176 LENPRLGSQSTNSSYTM--NTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPG 227
ST++ Y + + ++ +L+ N + DT Y+C+ N G C G
Sbjct: 5278 ---------STSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSG 5322
Score = 40.4 bits (93), Expect = 0.002
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 11/141 (7%)
Query: 83 FKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP 142
+K ++ +I I NV SD G+Y C+ A +E G + TV L+ P S
Sbjct: 5563 YKIASKNFHTSIHILNVDTSDIGEYHCK--AQNEVGSDTCVCTVKLKE--PPRFVSKLNS 5618
Query: 143 SSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFN 202
+ ++G EL+ + P W K+ ++ +S N T TLQF
Sbjct: 5619 LTVVAGEPAELQASIEGAQPI-FVQWLKEKEEVIR------ESENIRITFVENVATLQFA 5671
Query: 203 TVSKLDTGEYSCEARNSVGYR 223
+ G+Y C+ +N G R
Sbjct: 5672 KAEPANAGKYICQIKNDGGMR 5692
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 8/103 (7%)
Query: 123 EDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLG 182
E + +E+ AP + P G + + C+ + P + WFK G + E+ +
Sbjct: 3445 EQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIYESDKCS 3503
Query: 183 SQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRC 225
+S S Y +L+ +D GEY+C+A N G C
Sbjct: 3504 IRS--SKYI-----SSLEILRTQVVDCGEYTCKASNEYGSVSC 3539
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 9/132 (6%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I S +G+Y C S P + T E +P V ++G +
Sbjct: 6232 LKILQTDLSHSGQYSCSASNPLGTASSSARLTAR-EPKKSPFFDIKPVSIDVIAGESADF 6290
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C P TW KD + R G N + T T L+ V K D+G+Y+
Sbjct: 6291 ECHVTGAQPM-RITWSKDNKEI----RPGG---NYTITCVGNTPHLRILKVGKGDSGQYT 6342
Query: 214 CEARNSVGYRRC 225
C+A N VG C
Sbjct: 6343 CQATNDVGKDMC 6354
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 106 KYRCEVSAPSEQG----QNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGN 161
+Y VSA +E+G + L + ++++ PA + L+G +++ G
Sbjct: 22116 EYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFI-GR 22174
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P P TW KD + L + R+ ++ST ++ + K + D G Y + NS G
Sbjct: 22175 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE-------DVGHYVVKLTNSAG 22227
Score = 39.3 bits (90), Expect = 0.004
Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 23/177 (12%)
Query: 58 SSRLEWKKL----GRSVS--FVYYQQTLQGDFK--NRAEMIDFNIRIKNVTRSDAGKYRC 109
S L+W+K G+ + +V Y+Q+ +K N+ + D I + +A +Y
Sbjct: 30446 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL--EATEYEF 30503
Query: 110 EVSAPSEQGQNLEEDTVT-----LEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAP 164
V A +E G + T L AP + + G +L CQ G P P
Sbjct: 30504 RVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIV-GRPLP 30562
Query: 165 EYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
+ W++ G L+ QS + + +T TL T + D G Y+C A N VG
Sbjct: 30563 DIKWYRFGKELI-------QSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 30612
Score = 39.3 bits (90), Expect = 0.004
Identities = 33/128 (25%), Positives = 46/128 (35%), Gaps = 14/128 (10%)
Query: 100 TRSDAGKYRCEVSAPSEQG----QNLEEDTVTLEVLVAPAVPSCEVPSS--ALSGTVVEL 153
TR Y SA + ++LEE + T ++ A P S G
Sbjct: 32521 TRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARF 32580
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C D +G P P TW + G ++ S S T T + ++V D G YS
Sbjct: 32581 SC-DTDGEPVPTVTWLRKG-------QVLSTSARHQVTTTKYKSTFEISSVQASDEGNYS 32632
Query: 214 CEARNSVG 221
NS G
Sbjct: 32633 VVVENSEG 32640
Score = 38.9 bits (89), Expect = 0.006
Identities = 46/170 (27%), Positives = 68/170 (40%), Gaps = 24/170 (14%)
Query: 62 EWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNL 121
+W K GR + + + FKN + F + D+G+Y E+S +E G +
Sbjct: 4049 KWYKDGRPL---VASKKYRISFKNNVAQLKFY----SAELHDSGQYTFEIS--NEVGSSS 4099
Query: 122 EEDTVTLEVLVAPAVPSCEVP----SSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLE 177
E T T VL P P S ++GT L C+ P +WFKDG +
Sbjct: 4100 CETTFT--VLDRDIAPFFTKPLRNVDSVVNGTC-RLDCKIAGSLPM-RVSWFKDGKEIAA 4155
Query: 178 NPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPG 227
+ R T +L+ V D G ++C A NSVG + G
Sbjct: 4156 SDRYRIAFVEG-------TASLEIIRVDMNDAGNFTCRATNSVGSKDSSG 4198
Score = 38.9 bits (89), Expect = 0.006
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
Query: 102 SDAGKYRCEVSAPSEQGQN----LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
S +Y+ V A +E+G++ L + ++ + P++ S +G +++
Sbjct: 24276 SSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIP- 24334
Query: 158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
G P P +W KDG L + R+ + T +S ++ K G +K D G+Y+ A
Sbjct: 24335 VIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEG-------NKDDFGKYTVTAT 24387
Query: 218 NSVG 221
NS G
Sbjct: 24388 NSAG 24391
Score = 38.5 bits (88), Expect = 0.007
Identities = 56/228 (24%), Positives = 86/228 (37%), Gaps = 34/228 (14%)
Query: 7 HRLLLLLLR------YLVVALG-YHKAYGFSAPKDQQV------VTAVEYQEAILACKTP 53
HRLL+ R Y VVA G A F +D ++ V +E Q A++ +
Sbjct: 3112 HRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVN 3171
Query: 54 KKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSA 113
+ V + W K G ++F +Q K E + I +SDAG+Y
Sbjct: 3172 EDDVDAH--WYKDGIEINF-----QVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 3222
Query: 114 PSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGI 173
G+N T+ + P V P + SG C G P P+ +W+K+
Sbjct: 3223 ----GRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKE-- 3275
Query: 174 RLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
+L S + + + TL D Y+CEA+N G
Sbjct: 3276 -----EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 3318
Score = 38.5 bits (88), Expect = 0.007
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 15/145 (10%)
Query: 78 TLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVP 137
T + F+N + FN V +D+G+Y C+ A + G+ +T++ P
Sbjct: 8006 TYKMHFRNNVATLVFN----QVDINDSGEYICK--AENSVGEVSASTFLTVQEQKLPPSF 8059
Query: 138 SCEVPS-SALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKT 196
S ++ G V C P +W+KDG L ++P + + +++ T+N
Sbjct: 8060 SRQLRDVQETVGLPVVFDCAISGSEPI-SVSWYKDGKPLKDSPNVQTSFLDNTATLNI-- 8116
Query: 197 GTLQFNTVSKLDTGEYSCEARNSVG 221
F T L G+YSC A N +G
Sbjct: 8117 ----FKTDRSL-AGQYSCTATNPIG 8136
Score = 38.5 bits (88), Expect = 0.007
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQN----LEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
I N+T+ + +Y V A +E+G++ L V ++++ P V S G +
Sbjct: 23190 ITNLTQGE--EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDL 23247
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
++ G P P TW KDG+ L Q+T + T + TL K D G+
Sbjct: 23248 KIEVPIS-GRPKPTITWTKDGLPL-------KQTTRINVTDSLDLTTLSIKETHKDDGGQ 23299
Query: 212 YSCEARNSVGYR 223
Y N VG +
Sbjct: 23300 YGITVANVVGQK 23311
Score = 38.1 bits (87), Expect = 0.009
Identities = 37/165 (22%), Positives = 55/165 (33%), Gaps = 42/165 (25%)
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPS----------------------------EQGQNLEE 123
+ ++I N+T SD G+Y CE+S + Q E
Sbjct: 32774 YELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTE 32833
Query: 124 DTVT--LEVLVAPAVPSCEVPSSALSGTVVELRCQDK-----EGNPAPEYTWFKDGIRLL 176
TVT E + S V + L T V K G P P W KDG +
Sbjct: 32834 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 32893
Query: 177 ENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
+ + + L+ + D+G Y+C +NS G
Sbjct: 32894 QGGKYKLSEDKGGFF-------LEIHKTDTSDSGLYTCTVKNSAG 32931
Score = 37.7 bits (86), Expect = 0.012
Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 17/180 (9%)
Query: 54 KKTVSSRLEWKKLGR---SVSFVYYQQTLQGDFKNRAEMIDFN--IRIKNVTRSDAGKYR 108
KK +++L K G +++ + ++ K+R ++ +R+ +V D+G+Y
Sbjct: 4312 KKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYM 4371
Query: 109 CEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTW 168
CE A +E G + V ++ +P P L V L + G P E TW
Sbjct: 4372 CE--AQNEAGSDHCSSIVIVKE--SPYFTKEFKPIEVLKEYDVMLLAE-VAGTPPFEITW 4426
Query: 169 FKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK 228
FKD N L S ++ + +LQ D GEY C N VG C +
Sbjct: 4427 FKD------NTILRSGRKYKTFIQDHLV-SLQILKFVAADAGEYQCRVTNEVGSSICSAR 4479
Score = 37.7 bits (86), Expect = 0.012
Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 14/159 (8%)
Query: 69 SVSFVYYQQTLQGDFKNRAEMIDFN--IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTV 126
SVS+ + + K + + D + + + SD+G Y C A + G +E +
Sbjct: 7712 SVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTC--IATNMAGS--DECSA 7767
Query: 127 TLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQST 186
L V P+ P L+GT V K G P +WFK L+ R
Sbjct: 7768 PLTVREPPSFVQKPDPMDVLTGTNVTFTSIVK-GTPPFSVSWFKGSSELVPGDRC----- 7821
Query: 187 NSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRC 225
+ ++ L+ V +GEY+C N G C
Sbjct: 7822 --NVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 7858
Score = 37.4 bits (85), Expect = 0.016
Identities = 34/135 (25%), Positives = 48/135 (35%), Gaps = 18/135 (13%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPA---VPSCEVPSSALSGTV 150
+ + N+T D G Y C+ S D E+++ + E SA++ V
Sbjct: 3608 LELSNLTIQDRGVYSCKAS------NKFGADICQAELIIIDKPHFIKELEPVQSAINKKV 3661
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
L CQ E TW KDG +L + K TL+ D+G
Sbjct: 3662 -HLECQVDEDRKVT-VTWSKDGQKL-------PPGKDYKICFEDKIATLEIPLAKLKDSG 3712
Query: 211 EYSCEARNSVGYRRC 225
Y C A N G C
Sbjct: 3713 TYVCTASNEAGSSSC 3727
Score = 37.4 bits (85), Expect = 0.016
Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 15/127 (11%)
Query: 103 DAGKYRCEVSAPSEQGQN----LEEDTVTLEVLVAPAVP---SCEVPSSALSGTVVELRC 155
+ +YR + A + G+ L E + ++L P V +C + G + +
Sbjct: 17871 EGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILA 17930
Query: 156 QDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
+ K G P P+ TW K+G L+ R+ + LQ + D G+Y
Sbjct: 17931 RVK-GRPEPDITWTKEGKVLVREKRV-------DLIQDLPRVELQIKEAVRADHGKYIIS 17982
Query: 216 ARNSVGY 222
A+NS G+
Sbjct: 17983 AKNSSGH 17989
Score = 37.4 bits (85), Expect = 0.016
Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 16/132 (12%)
Query: 90 IDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGT 149
+++ R+ V + G+ E++ P + LE + L+V + +V A +G
Sbjct: 27236 VNYYFRVSAVNCAGQGE-PIEMNEPVQAKDILEAPEIDLDVALRTSV-------IAKAGE 27287
Query: 150 VVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDT 209
V++ K G P P TW KD L + R ++T+SS L V++ DT
Sbjct: 27288 DVQVLIPFK-GRPPPTVTWRKDEKNLGSDARYSIENTDSS-------SLLTIPQVTRNDT 27339
Query: 210 GEYSCEARNSVG 221
G+Y N VG
Sbjct: 27340 GKYILTIENGVG 27351
Score = 37.0 bits (84), Expect = 0.021
Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 26/138 (18%)
Query: 101 RSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVA-PAVPSCEVPSSALSGTVVELRCQDKE 159
++DAG RC ++ + E+ V+++V PA + SGT E+ +
Sbjct: 4561 KNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVK-----FSGTK-EITAK--- 4611
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
WFKDG L LGS+ S + L+ + K D+GEY+ E +N
Sbjct: 4612 --------WFKDGQELT----LGSKYKIS---VTDTVSILKIISTEKKDSGEYTFEVQND 4656
Query: 220 VGYRRCPGKRMQVDDLNI 237
VG C R+ V DL I
Sbjct: 4657 VGRSSCKA-RINVLDLII 4673
Score = 37.0 bits (84), Expect = 0.021
Identities = 42/153 (27%), Positives = 58/153 (37%), Gaps = 24/153 (15%)
Query: 73 VYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLV 132
+Y++ T+ AE+ FNI I S +G+Y C VS + Q T L V
Sbjct: 5941 IYFEDTV-------AELELFNIDI-----SQSGEYTCVVSNNAGQASC----TTRLFVKE 5984
Query: 133 APAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTM 192
A S G + L G TW KDG + + + +T
Sbjct: 5985 PAAFLKRLSDHSVEPGKSIILE-STYTGTLPISVTWKKDGFNITTSEKCNIVTTE----- 6038
Query: 193 NTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRC 225
KT L+ +K D G+YSCE N G C
Sbjct: 6039 --KTCILEILNSTKRDAGQYSCEIENEAGRDVC 6069
Score = 37.0 bits (84), Expect = 0.021
Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 41/163 (25%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQN-------------------------LEEDTVTLEV 130
+K++T+ D G YRC+V ++ G++ ++ T T+ +
Sbjct: 31628 VKDITKLDDGTYRCKVV--NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRL 31685
Query: 131 LVAPAVPSCEVP---SSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTN 187
L P P +P +A G V +P P TW+K G ++ +
Sbjct: 31686 LERP--PEFTLPLYNKTAYVGENVRFGVTITV-HPEPHVTWYKSGQKIKPG------DND 31736
Query: 188 SSYTMNTKTGTLQF--NTVSKLDTGEYSCEARNSVGYRRCPGK 228
YT + G Q N+V+ D EY+ ARN G C K
Sbjct: 31737 KKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 31779
Score = 36.6 bits (83), Expect = 0.027
Identities = 31/142 (21%), Positives = 57/142 (40%), Gaps = 13/142 (9%)
Query: 81 GDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPA-VPSC 139
G++K + + V + DAG+Y C S + + + + L V P +
Sbjct: 7256 GNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK----DSCSAQLGVQEPPRFIKKL 7311
Query: 140 EVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTL 199
E C+ G+P + W+KD + E+ + +S L
Sbjct: 7312 EPSRIVKQDEFTRYECK-IGGSPEIKVLWYKDETEIQESSKFRMSFVDS-------VAVL 7363
Query: 200 QFNTVSKLDTGEYSCEARNSVG 221
+ + +S D+G+Y+CEA N+ G
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAG 7385
Score = 36.6 bits (83), Expect = 0.027
Identities = 45/194 (23%), Positives = 72/194 (37%), Gaps = 24/194 (12%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
VT E + L+C + + R++W K GR + F + +++ ++
Sbjct: 8355 VTVSEGEYVQLSCHV-QGSEPIRIQWLKAGREIK---PSDRCSFSFASGTAVLE----LR 8406
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP------SSALSGTVV 151
+V ++D+G Y C+ S + + T+ + VAPA V S S VV
Sbjct: 8407 DVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVV 8466
Query: 152 ELR----CQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
E G+P P W K R L +Q L+ +K
Sbjct: 8467 EKTTATFIAKVGGDPIPNVKWTKGKWRQL------NQGGRVFIHQKGDEAKLEIRDTTKT 8520
Query: 208 DTGEYSCEARNSVG 221
D+G Y C A N G
Sbjct: 8521 DSGLYRCVAFNEHG 8534
Score = 36.6 bits (83), Expect = 0.027
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 30/200 (15%)
Query: 42 EYQEAILACKTPKKTV----------SSRLEWKKL-----GRSVSFVYYQQTLQGDFKNR 86
E ++A+ A +TP V S + WKK R + +V T + ++
Sbjct: 19873 ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRV 19932
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEED--TVTLEVLVAPAVPSCEVPSS 144
+ + K++T + +Y VSA +E G+ + V + +VAP + +P
Sbjct: 19933 MKSLSLQYSAKDLT--EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDL 19990
Query: 145 ---ALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQF 201
A + L+ K G PAP +W K L + R+ +S+ +NT TL
Sbjct: 19991 CYLAKENSNFRLKIPIK-GKPAPSVSWKKGEDPLATDTRVSVESS----AVNT---TLIV 20042
Query: 202 NTVSKLDTGEYSCEARNSVG 221
K D G+Y+ +N G
Sbjct: 20043 YDCQKSDAGKYTITLKNVAG 20062
Score = 35.8 bits (81), Expect = 0.047
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 13/94 (13%)
Query: 111 VSAPSEQGQNLEEDTVTL------EVLVAPAVPSCEVPSSALS---GTVVELRCQDKEGN 161
V A +E+G + D VT+ E+++ P V ++P + ++ G V L K G
Sbjct: 27535 VFAKNEKGLS---DPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK-GK 27590
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTK 195
P P +W KDG+ L E+ + T + T++ K
Sbjct: 27591 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIK 27624
Score = 35.4 bits (80), Expect = 0.061
Identities = 35/132 (26%), Positives = 48/132 (36%), Gaps = 9/132 (6%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I +S G+Y C S P + + + E V P V G
Sbjct: 7173 LQILQTDQSHIGQYNCSASNPLGTASSSAK-LILSEHEVPPFFDLKPVSVDLALGESGTF 7231
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
+C G + TW KD + R G N T+ T TL V K D G+Y+
Sbjct: 7232 KCH-VTGTAPIKITWAKDNREI----RPGG---NYKMTLVENTATLTVLKVGKGDAGQYT 7283
Query: 214 CEARNSVGYRRC 225
C A N G C
Sbjct: 7284 CYASNIAGKDSC 7295
Score = 35.4 bits (80), Expect = 0.061
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 22/140 (15%)
Query: 93 NIRIKNVTRSDAGKYRC----EVSAPSEQGQ-NLEEDTV--TLEVLVAPAVPSCEVPSSA 145
++ + V + D+G+Y C EV S Q N++E + + ++ V E S
Sbjct: 8209 HLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFK 8268
Query: 146 LSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVS 205
L G V G+ W+K+ I + ++N T T LQ
Sbjct: 8269 LEGRVA--------GSQPITVAWYKNNIEI-------QPTSNCEITFKNNTLVLQVRKAG 8313
Query: 206 KLDTGEYSCEARNSVGYRRC 225
D G Y+C+ N G C
Sbjct: 8314 MNDAGLYTCKVSNDAGSALC 8333
Score = 35.4 bits (80), Expect = 0.061
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 18/144 (12%)
Query: 36 QVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIR 95
Q T VE E IL C+ K + ++W K G+ + ++ D K R +
Sbjct: 12025 QDYTGVEKDEVILQCEISK--ADAPVKWFKDGKEIK-PSKNAVIKADGKKRM------LI 12075
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRC 155
+K +SD G+Y C+ G+ ED E+ + + S EV + + E+
Sbjct: 12076 LKKALKSDIGQYTCDCGTDKTSGKLDIEDR---EIKLVRPLHSVEVMETETARFETEISE 12132
Query: 156 QDKEGNPAPEYTWFKDGIRLLENP 179
D N W G LL+ P
Sbjct: 12133 DDIHAN------WKLKGEALLQTP 12150
Score = 35.4 bits (80), Expect = 0.061
Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 26/136 (19%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV---PSCEVPSSALS 147
+F IR KN + +SAPSE + + + + AP + P+ + + +
Sbjct: 20345 EFRIRAKNTAGA--------ISAPSESTETI----ICKDEYEAPTIVLDPTIKDGLTIKA 20392
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDG--IRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVS 205
G + L G P P+ +W K G IR + ++ S T+S T+ T
Sbjct: 20393 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT--------- 20443
Query: 206 KLDTGEYSCEARNSVG 221
+ D GEY+ A N G
Sbjct: 20444 RKDAGEYTITATNPFG 20459
Score = 35.4 bits (80), Expect = 0.061
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query: 106 KYRCEVSAPSEQGQN-LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK-----E 159
KY V+A + +G + E +E + +P E+ + +
Sbjct: 29412 KYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVS 29471
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P P TW K GI L + T SY++ L + V++ D G+Y+ EA N
Sbjct: 29472 GRPPPVITWSKQGIDLASRAII---DTTESYSL------LIVDKVNRYDAGKYTIEAENQ 29522
Query: 220 VG 221
G
Sbjct: 29523 SG 29524
Score = 35.0 bits (79), Expect = 0.080
Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 19/142 (13%)
Query: 83 FKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP 142
F N + FN V +D+G+Y C+ +E + PS
Sbjct: 6129 FTNNVATLVFN----KVNINDSGEYTCK----AENSIGTASSKTVFRIQERQLPPSFARQ 6180
Query: 143 SSALSGTV---VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTL 199
+ TV V L C+ G+ + W++DG+ L ++ L +S+ N TL
Sbjct: 6181 LKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGVLLRDDENL-----QTSFVDNV--ATL 6232
Query: 200 QFNTVSKLDTGEYSCEARNSVG 221
+ +G+YSC A N +G
Sbjct: 6233 KILQTDLSHSGQYSCSASNPLG 6254
Score = 35.0 bits (79), Expect = 0.080
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P P+ +WFKD +LE+ R ++T + T L+ + D+G+Y NS
Sbjct: 16844 GKPKPKVSWFKDEADVLEDDRTHIKTTPA-------TLALEKIKAKRSDSGKYCVVVENS 16896
Query: 220 VGYRR 224
G R+
Sbjct: 16897 TGSRK 16901
Score = 35.0 bits (79), Expect = 0.080
Identities = 31/122 (25%), Positives = 48/122 (39%), Gaps = 16/122 (13%)
Query: 106 KYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK-----EG 160
KY +SA ++ G +E++ P E+ + VV + +G
Sbjct: 20743 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 20802
Query: 161 NPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQ-FNTVSKLDTGEYSCEARNS 219
PAPE TW KD I L N + NT++ TL ++ DTG++ N
Sbjct: 20803 RPAPEVTWTKDNINL----------KNRANIENTESFTLLIIPECNRYDTGKFVMTIENP 20852
Query: 220 VG 221
G
Sbjct: 20853 AG 20854
Score = 35.0 bits (79), Expect = 0.080
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 8/77 (10%)
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
+G V+++ D G P P +W KDGI + E R ST++ + K +
Sbjct: 25803 AGEVLKINA-DIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK-------DCIR 25854
Query: 207 LDTGEYSCEARNSVGYR 223
DTG+Y +N G R
Sbjct: 25855 RDTGQYVLTLKNVAGTR 25871
Score = 35.0 bits (79), Expect = 0.080
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 8/60 (13%)
Query: 163 APEYTWFKDGIRLLENPRLG-SQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
A E TW+KDG +L EN S + +Y L+ N +++ D GEY CE G
Sbjct: 32746 AKEVTWYKDGKKLKENGHFQFHYSADGTY-------ELKINNLTESDQGEYVCEISGEGG 32798
Score = 34.7 bits (78), Expect = 0.10
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 14/129 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ I + +D+G Y C SA ++ G N +T V E P S +
Sbjct: 4732 LEISQLEGTDSGTYTC--SATNKAGHNQCSGHLT----VKEPPYFVEKPQSQDVNPNTRV 4785
Query: 154 RCQDKEGNPAP-EYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+ + G AP WFKD N L S + S + +T T +L+ D+G Y
Sbjct: 4786 QLKALVGGTAPMTIKWFKD------NKELHSGAARSVWKDDTST-SLELFAAKATDSGTY 4838
Query: 213 SCEARNSVG 221
C+ N VG
Sbjct: 4839 ICQLSNDVG 4847
Score = 34.7 bits (78), Expect = 0.10
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P TW K+GI + + R +T S + + T++ D G+Y+C N+
Sbjct: 7893 GTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVE-------DAGQYNCYIENA 7945
Query: 220 VGYRRC 225
G C
Sbjct: 7946 SGKDSC 7951
Score = 34.7 bits (78), Expect = 0.10
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
+GT V+LR G PAP W+KD L N + ++T T ++ +
Sbjct: 26886 AGTSVKLRA-GISGKPAPTIEWYKDDKELQTNALVCVENT-------TDLASILIKDADR 26937
Query: 207 LDTGEYSCEARNSVG 221
L++G Y + RN++G
Sbjct: 26938 LNSGCYELKLRNAMG 26952
Score = 34.3 bits (77), Expect = 0.14
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 111 VSAPSEQGQNLEEDTVT-LEVLVAPAVPSCEVPSSALSGTVVELRCQDKE--GNPAPEYT 167
+S PSE D VT L V P + S L+ C D G P P +
Sbjct: 19274 ISPPSEPS-----DPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVS 19328
Query: 168 WFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPG 227
W KDG L + M TL+ +V++ D+G+Y+ A NS G +
Sbjct: 19329 WKKDGTLL-------KPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI 19381
Query: 228 KRMQVD 233
K +D
Sbjct: 19382 KLKVLD 19387
Score = 33.5 bits (75), Expect = 0.23
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 7/63 (11%)
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
+G P P TWFKDG+ + + N T + +L ++ G Y+ EA+N
Sbjct: 27983 QGRPVPRVTWFKDGVEI-------EKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKN 28035
Query: 219 SVG 221
+ G
Sbjct: 28036 ASG 28038
Score = 33.5 bits (75), Expect = 0.23
Identities = 28/128 (21%), Positives = 52/128 (40%), Gaps = 21/128 (16%)
Query: 106 KYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL-RCQDKE----- 159
+Y V A ++ G + + + ++ P + P++ L+G +L C+
Sbjct: 28613 EYEFRVKAKNDAGYSEPREAFSSVIIKEPQIE----PTADLTGITNQLITCKAGSPFTID 28668
Query: 160 ----GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
G PAP+ TW + +RL E R+ +T T+ K + D+G Y
Sbjct: 28669 VPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS-------MRGDSGRYFLT 28721
Query: 216 ARNSVGYR 223
N+ G +
Sbjct: 28722 LENTAGVK 28729
Score = 33.1 bits (74), Expect = 0.30
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 7/83 (8%)
Query: 146 LSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVS 205
L G V C+ G P P+ W+KDG R+ R + +L+ V
Sbjct: 1303 LEGMGVTFHCK-MSGYPLPKIAWYKDGKRIKHGERYQMD------FLQDGRASLRIPVVL 1355
Query: 206 KLDTGEYSCEARNSVGYRRCPGK 228
D G Y+ A N G C GK
Sbjct: 1356 PEDEGIYTAFASNIKGNAICSGK 1378
Score = 33.1 bits (74), Expect = 0.30
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 19/123 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEV-PSSALSGTVVE 152
+ +K VT D + + +V S Q L+VL A + ++ +A+ +
Sbjct: 11630 LEMKEVTLDDISQIKAQVKELSSTAQ--------LKVLEADPYFTVKLHDKTAVEKDEIT 11681
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L+C+ + P WFKDG ++ +P+ ++ + K L+ D GEY
Sbjct: 11682 LKCEVSKDVPVK---WFKDGEEIVPSPKYSIKADGLRRILKIKKADLK-------DKGEY 11731
Query: 213 SCE 215
C+
Sbjct: 11732 VCD 11734
Score = 33.1 bits (74), Expect = 0.30
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 9/63 (14%)
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
+G PAPE W +D L+ S + SSYT+ L V++ D+G+Y N
Sbjct: 21885 KGRPAPEVKWARDHGESLDK---ASIESTSSYTL------LIVGNVNRFDSGKYILTVEN 21935
Query: 219 SVG 221
S G
Sbjct: 21936 SSG 21938
Score = 32.7 bits (73), Expect = 0.40
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P P TW K L + R+ ++T +S +N N + D+G Y ARN
Sbjct: 21091 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILN-------INECVRSDSGPYPLTARNI 21143
Query: 220 VG 221
VG
Sbjct: 21144 VG 21145
Score = 32.3 bits (72), Expect = 0.52
Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 5/62 (8%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P PE +WF+DG + + G Q + + L V+K ++G YS +A N
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQ-----ISFSDGRAKLTIPAVTKANSGRYSLKATNG 85
Query: 220 VG 221
G
Sbjct: 86 SG 87
Score = 32.3 bits (72), Expect = 0.52
Identities = 30/127 (23%), Positives = 47/127 (37%), Gaps = 17/127 (13%)
Query: 102 SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL---SGTVVELRCQDK 158
+D+G Y C++S ++ T + V + PS L +G CQ
Sbjct: 4833 TDSGTYICQLS------NDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQIT 4886
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
G P +W+ DG + + G + T Q + ++G Y CEARN
Sbjct: 4887 -GTPKIRVSWYLDGNEITAIQKHGISFIDG-------LATFQISGARVENSGTYVCEARN 4938
Query: 219 SVGYRRC 225
G C
Sbjct: 4939 DAGTASC 4945
Score = 32.3 bits (72), Expect = 0.52
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D + I +V SDAG+Y C + +++ + + + +E L V + E + + G
Sbjct: 11172 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAK--LVVEELPVRFVKTLEEEVTVVKGQP 11229
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENP 179
+ L C E N + W KDG ++E P
Sbjct: 11230 LYLSC---ELNKERDVVWRKDGKIVVEKP 11255
Score = 32.3 bits (72), Expect = 0.52
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 157 DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
D G P P W K L RL +ST+ + +++ K ++D+G Y +A
Sbjct: 22566 DIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAV-------RVDSGNYILKA 22618
Query: 217 RNSVGYR 223
+N G R
Sbjct: 22619 KNVAGER 22625
Score = 32.3 bits (72), Expect = 0.52
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P P+ T +DG+ L R ++ T + T+N K D G Y A NS
Sbjct: 26502 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESV-------TADAGRYEITAANS 26554
Query: 220 VG 221
G
Sbjct: 26555 SG 26556
Score = 32.0 bits (71), Expect = 0.68
Identities = 30/104 (28%), Positives = 35/104 (33%), Gaps = 12/104 (11%)
Query: 124 DTVTLEVLVAPAVPSCE------VPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLE 177
DT E P P+ V + G V CQ GNP P W K G+ L
Sbjct: 1066 DTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQ-VGGNPKPHVYWKKSGVPLTT 1124
Query: 178 NPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
R SY T L + D GEY+ RN G
Sbjct: 1125 GYRY-----KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163
Score = 32.0 bits (71), Expect = 0.68
Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 118 GQNLEE-DTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLL 176
G+ LEE D LE L P V L G + G P PE WF DG +++
Sbjct: 1440 GRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLK-VVGRPMPETFWFHDGQQIV 1498
Query: 177 ENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
+ T+ T +L + D+GE++ A+N G
Sbjct: 1499 ------NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG 1537
Score = 31.6 bits (70), Expect = 0.88
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 22/130 (16%)
Query: 95 RIKNVTRSDAGKYRCEVSAPSEQGQNL---EEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
R+K + R A K S P+E+ Q + E + L+V + + + +GT +
Sbjct: 13660 RVKALNRQGASK----PSRPTEEIQAVDTQEAPEIFLDVKLLAGL-------TVKAGTKI 13708
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
EL G P P+ TW K + L ++ R+ ++ K T+ + DTG
Sbjct: 13709 ELPAT-VTGKPEPKITWTKADMILKQDKRITIENV-------PKKSTVTIVDSKRSDTGT 13760
Query: 212 YSCEARNSVG 221
Y EA N G
Sbjct: 13761 YIIEAVNVCG 13770
Score = 31.6 bits (70), Expect = 0.88
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 14/144 (9%)
Query: 85 NRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSS 144
N+ ++ + ++++ + G+Y V A + G + TV P +P PS
Sbjct: 16067 NKRDVEELQFTVEDLV--EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMP----PSI 16120
Query: 145 ALS-------GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTG 197
L GT V + + K G P P TWFK + +N T+ + + T
Sbjct: 16121 DLKEFMEVEEGTNVNIVAKIK-GVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTC 16179
Query: 198 TLQFNTVSKLDTGEYSCEARNSVG 221
TL + DTG Y+ A N++G
Sbjct: 16180 TLVIPQSRRSDTGLYTITAVNNLG 16203
Score = 31.6 bits (70), Expect = 0.88
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
+G P P+ TW K + L + L +ST+ L+ V+K D G+Y N
Sbjct: 19718 KGRPPPKITWSKPNVNLRDRIGLDIKSTDFD-------TFLRCENVNKYDAGKYILTLEN 19770
Query: 219 SVG 221
S G
Sbjct: 19771 SCG 19773
Score = 31.6 bits (70), Expect = 0.88
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 22/125 (17%)
Query: 106 KYRCEVSAPSEQGQN----LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK--- 158
+Y V+A +E+G++ L + ++ + P+V E+P + V+ R Q K
Sbjct: 25363 EYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSV---ELPFHTFN---VKAREQLKIDV 25416
Query: 159 --EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
+G P W KDG L E R+ + +SS T+ +L SK D G Y
Sbjct: 25417 PFKGRPQATVNWRKDGQTLKETTRV---NVSSSKTVT----SLSIKEASKEDVGTYELCV 25469
Query: 217 RNSVG 221
NS G
Sbjct: 25470 SNSAG 25474
Score = 31.6 bits (70), Expect = 0.88
Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G V+ C+ + + + + TW+ G+R LEN S T L ++KL
Sbjct: 31582 GGHVKYVCKIENYDQSTQVTWYF-GVRQLEN------SEKYEITYEDGVAILYVKDITKL 31634
Query: 208 DTGEYSCEARNSVG 221
D G Y C+ N G
Sbjct: 31635 DDGTYRCKVVNDYG 31648
Score = 31.2 bits (69), Expect = 1.2
Identities = 18/78 (23%), Positives = 31/78 (39%), Gaps = 8/78 (10%)
Query: 144 SALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNT 203
+ + G V L C G P+P TW+++ ++ S + T + L
Sbjct: 953 TVIEGESVTLECHIS-GYPSPTVTWYREDYQI-------ESSIDFQITFQSGIARLMIRE 1004
Query: 204 VSKLDTGEYSCEARNSVG 221
D+G ++C A N G
Sbjct: 1005 AFAEDSGRFTCSAVNEAG 1022
Score = 30.8 bits (68), Expect = 1.5
Identities = 31/134 (23%), Positives = 50/134 (37%), Gaps = 14/134 (10%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
++ I V +DAG + C + ++ + L V P+ + L G+ V
Sbjct: 4169 SLEIIRVDMNDAGNFTCRAT----NSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVC 4224
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSY-TMNTKTGTLQFNTVSKLDTGE 211
L+ + P WFK L+ S S Y T +L+ V D+G
Sbjct: 4225 LKSTFQGSTPLT-IRWFKGNKELV--------SGGSCYITKEALESSLELYLVKTSDSGT 4275
Query: 212 YSCEARNSVGYRRC 225
Y+C+ N G C
Sbjct: 4276 YTCKVSNVAGGVEC 4289
Score = 30.8 bits (68), Expect = 1.5
Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 7/66 (10%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P +W KD + SQS S TM K+ L+ + D +YSC N
Sbjct: 6952 GTPPISVSWIKDEYLI-------SQSERCSITMTEKSTILEILESTIEDYAQYSCLIENE 7004
Query: 220 VGYRRC 225
G C
Sbjct: 7005 AGQDIC 7010
Score = 30.8 bits (68), Expect = 1.5
Identities = 40/160 (25%), Positives = 59/160 (36%), Gaps = 37/160 (23%)
Query: 106 KYRCEVSAPSEQGQNLEEDTV----------TLEVLVAPAVPSCEVPSSALSGTVVELRC 155
KYR V A +E G++ DT EV + C V +G+ + +
Sbjct: 15776 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLV---CKAGSQIRIPA 15832
Query: 156 QDKEGNPAPEYTW---------FKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
K G P P+ +W KDG+ + + NSS + +
Sbjct: 15833 VIK-GRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS--------VIIIPECKR 15883
Query: 207 LDTGEYSCEARNSVGYR--RCPGKRMQV----DDLNISGI 240
TG+YS A+N G + C K M V DL +S I
Sbjct: 15884 SHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDI 15923
Score = 30.8 bits (68), Expect = 1.5
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 25/123 (20%)
Query: 102 SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGN 161
SDA R +V AP + +DTV L+ +G L D G
Sbjct: 21447 SDAITCRDDVEAPKIKVDVKFKDTVILK-----------------AGEAFRLEA-DVSGR 21488
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P P W KDG L +L + + S + K T + D+G Y+ A N G
Sbjct: 21489 PPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDST-------RRDSGAYTLTATNPGG 21541
Query: 222 YRR 224
+ +
Sbjct: 21542 FAK 21544
Score = 30.0 bits (66), Expect = 2.6
Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 9/128 (7%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ I VT++++G+Y + + S Q + E V E V + + G+ V L
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-SMTVRQGSQVRL 123
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
+ + G P P +++DG + S + + +L D+G YS
Sbjct: 124 QVR-VTGIPTPVVKFYRDGAEI-------QSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 214 CEARNSVG 221
A NSVG
Sbjct: 176 VNATNSVG 183
Score = 28.9 bits (63), Expect = 5.7
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 167 TWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
TW KDG + E+P+ + + K L V D GEY+C R
Sbjct: 11150 TWMKDGSNIRESPK-------HRFIADGKDRKLHIIDVQLSDAGEYTCVLR 11193
Score = 28.5 bits (62), Expect = 7.5
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 8/71 (11%)
Query: 157 DKEGNPAPEYTWFKDGIRLLEN-PRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCE 215
D G P P+ W KDG L E R+ +ST T+ K + D G+Y +
Sbjct: 24730 DIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVK-------DCIRTDGGQYILK 24782
Query: 216 ARNSVGYRRCP 226
N G + P
Sbjct: 24783 LSNVGGTKSIP 24793
Score = 28.1 bits (61), Expect = 9.8
Identities = 35/153 (22%), Positives = 55/153 (35%), Gaps = 21/153 (13%)
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+ + I +VT D +Y V A ++ G++ + +T+ + P + L +
Sbjct: 31748 YQLTINSVTTDDDAEYT--VVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL---LA 31802
Query: 152 ELRCQDKE---------GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFN 202
CQ+ + G P P W KDG L P + Y L
Sbjct: 31803 NAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYY------ALHIR 31856
Query: 203 TVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDL 235
DTG Y A N+ G C +QV+ L
Sbjct: 31857 DTLPEDTGYYRVTATNTAGSTSCQA-HLQVERL 31888
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 11/154 (7%)
Query: 69 SVSFVYYQQTLQGDFKNRAEMI-DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVT 127
+VS++Y+ + + NR M+ + N++I N+ +SD G YRCE + + + V
Sbjct: 145 AVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVI 204
Query: 128 LEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTN 187
+ V A ++P ++A G + C+ G+P P +WF++G +L+E N
Sbjct: 205 VNVPPAISMPQKSFNATAERGEEMTFSCR-ASGSPEPAISWFRNG-KLIEE--------N 254
Query: 188 SSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
Y + L + D G Y C A N G
Sbjct: 255 EKYILKGSNTELTVRNIINSDGGPYVCRATNKAG 288
Score = 54.7 bits (130), Expect = 1e-07
Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 11/185 (5%)
Query: 39 TAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKN 98
T E + L C + + + WK+ +F ++L G + + + ++ IK+
Sbjct: 311 TTYENGQVTLVCDAEGEPIPE-ITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKD 369
Query: 99 VTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK 158
V SD+G+Y CE A S G + + ++ L++ AP S + + G + + C D
Sbjct: 370 VKLSDSGRYDCE--AASRIGGH--QKSMYLDIEYAPKFISNQTIYYSWEGNPINISC-DV 424
Query: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
+ NP W +D + L +TN + L+ S D G Y+C A N
Sbjct: 425 KSNPPASIHWRRDKLVL-----PAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
Query: 219 SVGYR 223
+G R
Sbjct: 480 HIGTR 484
Score = 43.5 bits (101), Expect = 2e-04
Identities = 38/130 (29%), Positives = 53/130 (40%), Gaps = 12/130 (9%)
Query: 88 EMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS 147
E + + I N DAG YRC+ A +GQ +E TV LE+ P
Sbjct: 72 EGVRSRLTIYNANIEDAGIYRCQ--ATDAKGQT-QEATVVLEIYQKLTFREVVSPQEFKQ 128
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G E+ C+ +PAP +W L N + + S N + LQ ++K
Sbjct: 129 GEDAEVVCR-VSSSPAPAVSW------LYHNEEVTTISDNRFAML--ANNNLQILNINKS 179
Query: 208 DTGEYSCEAR 217
D G Y CE R
Sbjct: 180 DEGIYRCEGR 189
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 59.3 bits (142), Expect = 4e-09
Identities = 57/193 (29%), Positives = 85/193 (44%), Gaps = 35/193 (18%)
Query: 37 VVTAVEYQEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFN 93
VV AV +E +L C+ P+ T++ W+K G +V+ Q L G
Sbjct: 2765 VVRAVAEEEVLLPCEASGIPRPTIT----WQKEGLNVATGVSTQVLPGG----------Q 2810
Query: 94 IRIKNVTRSDAGKYRC--EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+RI + + DAG Y C + SA S G+ L V V P + + S G+
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKT------RLVVQVPPVIENGLPDLSTTEGSHA 2864
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C+ + G+P P TW KDG P G++ +T+ +G L + D G
Sbjct: 2865 FLPCKAR-GSPEPNITWDKDG-----QPVSGAEG---KFTIQP-SGELLVKNLEGQDAGT 2914
Query: 212 YSCEARNSVGYRR 224
Y+C A N+VG R
Sbjct: 2915 YTCTAENAVGRAR 2927
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 30/193 (15%)
Query: 31 APKDQQVVTAVEY-QEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNR 86
AP+ Q V +A+L+C+T P+ TV+ W K G+ + Q L+G +
Sbjct: 1843 APRGPQDAVLVRVGDKAVLSCETDALPEPTVT----WYKDGQPLVLAQRTQALRGGQR-- 1896
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL 146
+ I+ SD G Y C+VS + G+ + T+T++V P E S +
Sbjct: 1897 -------LEIQEAQVSDKGLYSCKVS--NVAGEAVRTFTLTVQVPPTFENPKTETVSQ-V 1946
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
+G+ + L C D G PAP TW KD + + +++ + + ++ G LQ + +
Sbjct: 1947 AGSPLVLTC-DVSGVPAPTVTWLKDRMPV---------ESSAVHGVVSRGGRLQLSRLQP 1996
Query: 207 LDTGEYSCEARNS 219
G Y+C A N+
Sbjct: 1997 AQAGTYTCVAENT 2009
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 20/133 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL--SGTVV 151
+RI V +DAG + C ++P+ + + TL+V V P + E + + G++V
Sbjct: 2178 LRISKVQLADAGIFTCVAASPA----GVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLV 2233
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
EL C+ + G P P +W KDG LL SQS +LQ V D+G
Sbjct: 2234 ELPCEAR-GVPLPLVSWMKDGEPLL------SQSLEQG-------PSLQLEAVGAGDSGT 2279
Query: 212 YSCEARNSVGYRR 224
YSC A + G R
Sbjct: 2280 YSCVAVSEAGEAR 2292
Score = 53.1 bits (126), Expect = 3e-07
Identities = 42/129 (32%), Positives = 61/129 (47%), Gaps = 16/129 (12%)
Query: 94 IRIKNVTRSDAGKYRC-EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
+ + + SD+G+Y C VSA E Q+ V L+V + P++ E+ S ++ V
Sbjct: 844 LTLASARASDSGRYSCVAVSAVGEDRQD-----VVLQVHMPPSILGEELNVSVVANESVA 898
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L CQ P P +W+KDG R LE PR G ++ LQ + D G Y
Sbjct: 899 LECQS-HAMPPPVLSWWKDG-RPLE-PRPGVH-------LSADKALLQVDRADVWDAGHY 948
Query: 213 SCEARNSVG 221
+CEA N G
Sbjct: 949 TCEALNQAG 957
Score = 50.8 bits (120), Expect = 1e-06
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 15/136 (11%)
Query: 86 RAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSA 145
R ++ + ++ I R DAG+Y+C A +E G + + V L + AP +
Sbjct: 3074 RHQLQNGSLTIHRTERDDAGRYQC--LAENEMG--VAKKVVILVLQSAPVFQVEPQDMTV 3129
Query: 146 LSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVS 205
SG V LRCQ G P P W + G L + RL + S + N +TG
Sbjct: 3130 RSGDDVALRCQ-ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETG-------- 3180
Query: 206 KLDTGEYSCEARNSVG 221
D G Y C A N +G
Sbjct: 3181 --DAGTYDCVAHNLLG 3194
Score = 49.7 bits (117), Expect = 3e-06
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 15/129 (11%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS-SALSGTVVE 152
+++ +DA Y C +E E TL V V P + ++ +A+ + V
Sbjct: 1710 LQVSTAEVADAASYMCV----AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVS 1765
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C D +P PE TW+KD L S + T TLQ D+G Y
Sbjct: 1766 LPC-DVHAHPNPEVTWYKDSQAL---------SLGEEVFLLPGTHTLQLGRARLSDSGMY 1815
Query: 213 SCEARNSVG 221
+CEA N+ G
Sbjct: 1816 TCEALNAAG 1824
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 21/137 (15%)
Query: 90 IDFNIRIKNVTR-SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS- 147
++ N R V R DAG Y C +P+ E + + V P + P +
Sbjct: 2348 LENNSRATRVLRVRDAGLYTCLAESPA----GAIEKSFRVRVQAPPNIVGPRGPRFVVGL 2403
Query: 148 --GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGT-LQFNTV 204
G +V L C E PAP+ TW +DGI L E+ ++T + G LQ +
Sbjct: 2404 APGQLV-LECS-VEAEPAPKITWHRDGIVLQED----------AHTQFPERGRFLQLQAL 2451
Query: 205 SKLDTGEYSCEARNSVG 221
S D+G+YSC ARN+ G
Sbjct: 2452 STADSGDYSCTARNAAG 2468
Score = 48.9 bits (115), Expect = 5e-06
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+RI D G+Y+C +P+ Q + L V P + + + +V
Sbjct: 274 LRITGSHVGDEGRYQCVAFSPAGQ----QARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 329
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
+L C+ + G P P TWFKDG L ST YT + LQ D G
Sbjct: 330 QLLCEAR-GVPTPNITWFKDGALL-------PTSTKVVYTRGGR--QLQLGRAQSSDAGV 379
Query: 212 YSCEARNSVG 221
Y+C+A N+VG
Sbjct: 380 YTCKASNAVG 389
Score = 48.9 bits (115), Expect = 5e-06
Identities = 50/184 (27%), Positives = 73/184 (39%), Gaps = 26/184 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
++ E A L CK + + + W K G+ VS + T+Q + + +K
Sbjct: 2856 LSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---------LLVK 2905
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
N+ DAG Y C +E V L +LV P + S G + LRC
Sbjct: 2906 NLEGQDAGTYTCT----AENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 2961
Query: 158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
+ G+P P W + + E + Q S TLQ VS+ D+G Y C A
Sbjct: 2962 R-GSPTPRIGWTVNDRPVTEG--VSEQDGGS---------TLQRAAVSREDSGTYVCWAE 3009
Query: 218 NSVG 221
N VG
Sbjct: 3010 NRVG 3013
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+++ D+G Y C S + + + ++EVLV P++ + ++ L G
Sbjct: 1217 LKMTQTQEQDSGLYSCLASNEAGEARR----NFSVEVLVPPSIENEDLEEVIKVLDGQTA 1272
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C + G+P P+ TWFKDG L + ++ ++ LQ + G
Sbjct: 1273 HLMC-NVTGHPQPKLTWFKDGRPL---------ARGDAHHISPDGVLLQVLQANLSSAGH 1322
Query: 212 YSCEARNSVG 221
YSC A N+VG
Sbjct: 1323 YSCIAANAVG 1332
Score = 45.4 bits (106), Expect = 6e-05
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 14/130 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSS--ALSGTVV 151
+++ + + AG Y C +E Q + VLVAP + S V L G V
Sbjct: 1989 LQLSRLQPAQAGTYTCV----AENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV 2044
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C+ +G P P+ W KDG L Q G+L + D G
Sbjct: 2045 RLDCE-ADGQPPPDVAWLKDGSPL-------GQDMGPHLRFYLDGGSLVLKGLRASDAGA 2096
Query: 212 YSCEARNSVG 221
Y+C A N G
Sbjct: 2097 YTCVAHNPAG 2106
Score = 45.1 bits (105), Expect = 8e-05
Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 17/134 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV---PSCEVPSSALSGTV 150
+RI+ SDAG YRC S + E L V V P + PS +P L T
Sbjct: 750 LRIEQAQLSDAGSYRCVASNVA----GSTELRYGLRVNVPPRITLPPS--LPGPVLVNTP 803
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C + G P+P W KDG NP + + + TL S D+G
Sbjct: 804 VRLTC-NATGAPSPTLMWLKDG-----NPVSPAGTPGLQVFPGGRVLTLASARAS--DSG 855
Query: 211 EYSCEARNSVGYRR 224
YSC A ++VG R
Sbjct: 856 RYSCVAVSAVGEDR 869
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 18/130 (13%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I+ V D G Y C +A + G++ E V L+VLV P + V + L V L
Sbjct: 659 LQIEKVDLRDEGIYTC--AATNLAGESKRE--VALKVLVPPNIEPGPVNKAVLENASVTL 714
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNS--SYTMNTKTGTLQFNTVSKLDTGE 211
C G P P+ +WFK G Q +S T++ L+ D G
Sbjct: 715 ECL-ASGVPPPDVSWFK-----------GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 762
Query: 212 YSCEARNSVG 221
Y C A N G
Sbjct: 763 YRCVASNVAG 772
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 17/129 (13%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL---SGTVVE 152
+K + SDAG Y C P+ + L T+ VLV P + S L G +V
Sbjct: 2086 LKGLRASDAGAYTCVAHNPAGEDARLH----TVNVLVPPTIKQGADGSGTLVSRPGELVT 2141
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+ C + G+P +W KDG+ L + R ++ TL+ + V D G +
Sbjct: 2142 MVCPVR-GSPPIHVSWLKDGLPLPLSQRT---------LLHGSGHTLRISKVQLADAGIF 2191
Query: 213 SCEARNSVG 221
+C A + G
Sbjct: 2192 TCVAASPAG 2200
Score = 41.6 bits (96), Expect = 9e-04
Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSC---EVPSSALSGTV 150
+++ SDAG Y C+ S E L+V V P + A++G
Sbjct: 367 LQLGRAQSSDAGVYTCKAS----NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRP 422
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C + G+P+P +W +G+ + E ++ + T L+ + + +G
Sbjct: 423 VALECVAR-GHPSPTLSWHHEGLPVAE---------SNESRLETDGSVLRLESPGEASSG 472
Query: 211 EYSCEARNSVG 221
YSC A + G
Sbjct: 473 LYSCVASSPAG 483
Score = 41.6 bits (96), Expect = 9e-04
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 94 IRIKNVTRSDAGKYRCEVSAP-SEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
++I V +AG+Y C+ S E + E +T V++ E + S TV
Sbjct: 1615 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTV-S 1673
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L+C GNP P +W ++G+ +PRL LQ +T D Y
Sbjct: 1674 LQCPAL-GNPVPTISWLQNGLPFSPSPRLQVLEDGQ---------VLQVSTAEVADAASY 1723
Query: 213 SCEARNSVG 221
C A N G
Sbjct: 1724 MCVAENQAG 1732
Score = 41.6 bits (96), Expect = 9e-04
Identities = 46/188 (24%), Positives = 76/188 (40%), Gaps = 30/188 (15%)
Query: 38 VTAVEYQEAILACK---TPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
+T + A+L C+ +PK V W K G+ + F + QG ++ ++ N
Sbjct: 2582 LTLTAHTPALLPCEASGSPKPLVV----WWKDGQKLDF----RLQQGAYR----LLPSNA 2629
Query: 95 RIKNVTR-SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ D+ ++ C VS + L + TV V P + + + V L
Sbjct: 2630 LLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----VPPTIADDQTDFTVTMMAPVVL 2685
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C G PAP +W K G +L + S Y ++ +G L+ + G Y+
Sbjct: 2686 TCHST-GIPAPTVSWSKAGAQL--------GARGSGYRVSP-SGALEIGQALPIHAGRYT 2735
Query: 214 CEARNSVG 221
C ARNS G
Sbjct: 2736 CSARNSAG 2743
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/190 (22%), Positives = 73/190 (38%), Gaps = 25/190 (13%)
Query: 35 QQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
++V+ ++ Q A L C +L W K GR ++ +GD + +
Sbjct: 1261 EEVIKVLDGQTAHLMCNVTGHP-QPKLTWFKDGRPLA--------RGD-AHHISPDGVLL 1310
Query: 95 RIKNVTRSDAGKYRC-EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++ S AG Y C +A E+ ++ + + ++ A S + + + L
Sbjct: 1311 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISL 1370
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGT--LQFNTVSKLDTGE 211
C+ P+P TW KDG +S + GT LQ K D G+
Sbjct: 1371 ICEAL-AFPSPNITWMKDGAPF-----------EASRNIQLLPGTHGLQILNAQKEDAGQ 1418
Query: 212 YSCEARNSVG 221
Y+C N +G
Sbjct: 1419 YTCVVTNELG 1428
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 21/135 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV----PSCEVPSSALSGT 149
++I N + DAG+Y C V+ +E G+ ++ V EVL+ P++ P EV +
Sbjct: 1406 LQILNAQKEDAGQYTCVVT--NELGEAVKNYHV--EVLIPPSISKDDPLGEVGVKEVKTK 1461
Query: 150 V---VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
V + L C+ P P W+KDG + + RL + + LQ
Sbjct: 1462 VNSTLTLECESW-AVPPPTIRWYKDGQPVTPSSRL---------QVLGEGRLLQIQPTQV 1511
Query: 207 LDTGEYSCEARNSVG 221
D+G Y C A N G
Sbjct: 1512 SDSGRYLCVATNVAG 1526
Score = 39.7 bits (91), Expect = 0.003
Identities = 40/133 (30%), Positives = 56/133 (42%), Gaps = 27/133 (20%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTV 150
+++++ V D+G Y C A SE G+ +T V+ P + P+ S G
Sbjct: 2266 SLQLEAVGAGDSGTYSCV--AVSEAGEARRHFQLT--VMEPPHIEDSGQPTELSLTPGAP 2321
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRL--LENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
+EL C D +G P P TW KDG L LEN NS T + D
Sbjct: 2322 MELLC-DAQGTPQPNITWHKDGQALTRLEN--------NSRAT----------RVLRVRD 2362
Query: 209 TGEYSCEARNSVG 221
G Y+C A + G
Sbjct: 2363 AGLYTCLAESPAG 2375
Score = 39.7 bits (91), Expect = 0.003
Identities = 44/193 (22%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 32 PKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
P+ + V + + +L C + + ++ W + G + Q+ F R +
Sbjct: 2394 PRGPRFVVGLAPGQLVLECSVEAEP-APKITWHRDG-----IVLQEDAHTQFPERGRFL- 2446
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+++ ++ +D+G Y C +A + G +E+ P + S +
Sbjct: 2447 ---QLQALSTADSGDYSC--TARNAAGST--SVAFRVEIHTVPTIRSGPPAVNVSVNQTA 2499
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L CQ +G PAP +W KD + L +PR S G+L+ V D G
Sbjct: 2500 LLPCQ-ADGVPAPLVSWRKDRVPL--DPR-------SPRFEILPEGSLRIQPVLAQDAGH 2549
Query: 212 YSCEARNSVGYRR 224
Y C A NS G R
Sbjct: 2550 YLCLASNSAGSDR 2562
Score = 38.9 bits (89), Expect = 0.006
Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 15/121 (12%)
Query: 103 DAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL-SGTVVELRCQDKEGN 161
DAG Y CE A ++ G++ E L V VAP P E + + G L C+ + G
Sbjct: 944 DAGHYTCE--ALNQAGRS--EKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR-GV 998
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL-DTGEYSCEARNSV 220
P P+ +W KDG + L G Q ++ G L + ++L G Y+CE N V
Sbjct: 999 PFPKISWRKDG-QPLPGEGAGLQHVSA-------VGRLLYLGQAQLAQEGTYTCECSNVV 1050
Query: 221 G 221
G
Sbjct: 1051 G 1051
Score = 37.0 bits (84), Expect = 0.021
Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 18/125 (14%)
Query: 99 VTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS--GTVVELRCQ 156
V+R D+G Y C +E + + V AP + E S + G ++L C
Sbjct: 2996 VSREDSGTYVCW----AENRVGRTQAVSFVHVKEAPVLQG-EAFSYLVEPVGGSIQLDCV 3050
Query: 157 DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
+ G+P P+ W KDG+ L S + G+L + + D G Y C A
Sbjct: 3051 VR-GDPVPDIHWIKDGLPL----------RGSHLRHQLQNGSLTIHRTERDDAGRYQCLA 3099
Query: 217 RNSVG 221
N +G
Sbjct: 3100 ENEMG 3104
Score = 34.7 bits (78), Expect = 0.10
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 7/78 (8%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV--PSCEVPSSALSGTVVEL 153
+ +V+ +D+G Y C+ A +E G L V V P++ + S ++G + L
Sbjct: 61 LASVSPADSGDYECQ--ATNEVGSTSRR--AKLVVYVPPSIREDGRKANVSGMAGQSLTL 116
Query: 154 RCQDKEGNPAPEYTWFKD 171
C D G P PE W KD
Sbjct: 117 EC-DANGFPVPEIVWLKD 133
Score = 31.6 bits (70), Expect = 0.88
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 8/62 (12%)
Query: 160 GNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNS 219
G P P+ TW K P G + G+L +VS D+G+Y C+A N
Sbjct: 28 GTPKPQVTWRKGPS---SEPLHGQPGVAV-----LEEGSLFLASVSPADSGDYECQATNE 79
Query: 220 VG 221
VG
Sbjct: 80 VG 81
Score = 28.1 bits (61), Expect = 9.8
Identities = 42/190 (22%), Positives = 72/190 (37%), Gaps = 27/190 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
V+ V+ A L C K + + W++ G+ V L +N+ + ++ ++
Sbjct: 1077 VSVVQDGVATLECNATGKPPPT-VTWERDGQPVG-----AELGLQLQNQGQ----SLHVE 1126
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV---VELR 154
+ G+Y C +E E L VLV P + P + ++ + + L
Sbjct: 1127 RAQAAHTGRYSCV----AENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 1182
Query: 155 CQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSC 214
C+ G P P WF+ E P + T + L+ + D+G YSC
Sbjct: 1183 CEAM-GIPPPAIRWFRG-----EEPVSPGEDTY----LLAGGWMLKMTQTQEQDSGLYSC 1232
Query: 215 EARNSVGYRR 224
A N G R
Sbjct: 1233 LASNEAGEAR 1242
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 59.3 bits (142), Expect = 4e-09
Identities = 57/193 (29%), Positives = 85/193 (44%), Gaps = 35/193 (18%)
Query: 37 VVTAVEYQEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFN 93
VV AV +E +L C+ P+ T++ W+K G +V+ Q L G
Sbjct: 3956 VVRAVAEEEVLLPCEASGIPRPTIT----WQKEGLNVATGVSTQVLPGG----------Q 4001
Query: 94 IRIKNVTRSDAGKYRC--EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+RI + + DAG Y C + SA S G+ L V V P + + S G+
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKT------RLVVQVPPVIENGLPDLSTTEGSHA 4055
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C+ + G+P P TW KDG P G++ +T+ +G L + D G
Sbjct: 4056 FLPCKAR-GSPEPNITWDKDG-----QPVSGAEG---KFTIQP-SGELLVKNLEGQDAGT 4105
Query: 212 YSCEARNSVGYRR 224
Y+C A N+VG R
Sbjct: 4106 YTCTAENAVGRAR 4118
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 30/193 (15%)
Query: 31 APKDQQVVTAVEY-QEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNR 86
AP+ Q V +A+L+C+T P+ TV+ W K G+ + Q L+G +
Sbjct: 3034 APRGPQDAVLVRVGDKAVLSCETDALPEPTVT----WYKDGQPLVLAQRTQALRGGQR-- 3087
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL 146
+ I+ SD G Y C+VS + G+ + T+T++V P E S +
Sbjct: 3088 -------LEIQEAQVSDKGLYSCKVS--NVAGEAVRTFTLTVQVPPTFENPKTETVSQ-V 3137
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
+G+ + L C D G PAP TW KD + + +++ + + ++ G LQ + +
Sbjct: 3138 AGSPLVLTC-DVSGVPAPTVTWLKDRMPV---------ESSAVHGVVSRGGRLQLSRLQP 3187
Query: 207 LDTGEYSCEARNS 219
G Y+C A N+
Sbjct: 3188 AQAGTYTCVAENT 3200
Score = 55.8 bits (133), Expect = 4e-08
Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 20/129 (15%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
++R+ V D+G Y C S P+ + L V V P V L G ++
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASH----RYVLGVQVPPQVQPGPRVLKVLVGEALD 1138
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C EGNP P+ +W KDG+ L G Q G++ F + D G Y
Sbjct: 1139 LNCV-AEGNPEPQLSWSKDGVVLQGR---GPQ------------GSVHFAAIRTSDAGRY 1182
Query: 213 SCEARNSVG 221
CEA NS G
Sbjct: 1183 RCEASNSAG 1191
Score = 55.5 bits (132), Expect = 6e-08
Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 15/160 (9%)
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL 146
A++ D ++ I + +D G+Y+C S + +V L V AP V
Sbjct: 565 AQLADLSLEISGIIPTDGGRYQCVAS----NANGVTRASVWLLVREAPQVSIHTSSQHFS 620
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
G V++ C G P P +W ++ L E+ R+ + GTL V+
Sbjct: 621 QGVEVKVSCS-ASGYPTPHISWSRESQALQEDSRIHVDAQ----------GTLIIQGVAP 669
Query: 207 LDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVV 246
D G YSC+A N VG + D ++S + A V+V
Sbjct: 670 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 709
Score = 53.9 bits (128), Expect = 2e-07
Identities = 42/130 (32%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRC-EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
+ + + SD+G+Y C VSA E Q+ V L+V + P++ E+ S ++ V
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQD-----VVLQVHMPPSILGEELNVSVVANESVA 2089
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L CQ P P +W+KDG R LE PR G ++ LQ + D G Y
Sbjct: 2090 LECQS-HAMPPPVLSWWKDG-RPLE-PRPGVH-------LSADKALLQVDRADVWDAGHY 2139
Query: 213 SCEARNSVGY 222
+CEA N G+
Sbjct: 2140 TCEALNQAGH 2149
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 20/133 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL--SGTVV 151
+RI V +DAG + C ++P+ + + TL+V V P + E + + G++V
Sbjct: 3369 LRISKVQLADAGIFTCVAASPA----GVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLV 3424
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
EL C+ + G P P +W KDG LL SQS +LQ V D+G
Sbjct: 3425 ELPCEAR-GVPLPLVSWMKDGEPLL------SQSLEQG-------PSLQLEAVGAGDSGT 3470
Query: 212 YSCEARNSVGYRR 224
YSC A + G R
Sbjct: 3471 YSCVAVSEAGEAR 3483
Score = 50.8 bits (120), Expect = 1e-06
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 15/136 (11%)
Query: 86 RAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSA 145
R ++ + ++ I R DAG+Y+C A +E G + + V L + AP +
Sbjct: 4265 RHQLQNGSLTIHRTERDDAGRYQC--LAENEMG--VAKKVVILVLQSAPVFQVEPQDMTV 4320
Query: 146 LSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVS 205
SG V LRCQ G P P W + G L + RL + S + N +TG
Sbjct: 4321 RSGDDVALRCQ-ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETG-------- 4371
Query: 206 KLDTGEYSCEARNSVG 221
D G Y C A N +G
Sbjct: 4372 --DAGTYDCVAHNLLG 4385
Score = 50.1 bits (118), Expect = 2e-06
Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 18/152 (11%)
Query: 70 VSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLE 129
+S+ Q LQ D + + + I+ V DAG Y C+ A +E G +++TVTL
Sbjct: 639 ISWSRESQALQEDSRIHVDA-QGTLIIQGVAPEDAGNYSCQ--ATNEVGT--DQETVTLY 693
Query: 130 VLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSS 189
P+V + G L C+ G P P W++ G+ ++ P GS S
Sbjct: 694 YTDPPSVSAVNAVVLVAVGEEAVLVCE-ASGVPPPRVIWYRGGLEMILAPE-GSSS---- 747
Query: 190 YTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
G L+ + D G Y+C A N +G
Sbjct: 748 -------GKLRIPAAQERDAGTYTCRAVNELG 772
Score = 49.7 bits (117), Expect = 3e-06
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 15/129 (11%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS-SALSGTVVE 152
+++ +DA Y C +E E TL V V P + ++ +A+ + V
Sbjct: 2901 LQVSTAEVADAASYMCV----AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVS 2956
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C D +P PE TW+KD L S + T TLQ D+G Y
Sbjct: 2957 LPC-DVHAHPNPEVTWYKDSQAL---------SLGEEVFLLPGTHTLQLGRARLSDSGMY 3006
Query: 213 SCEARNSVG 221
+CEA N+ G
Sbjct: 3007 TCEALNAAG 3015
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 21/137 (15%)
Query: 90 IDFNIRIKNVTR-SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS- 147
++ N R V R DAG Y C +P+ E + + V P + P +
Sbjct: 3539 LENNSRATRVLRVRDAGLYTCLAESPA----GAIEKSFRVRVQAPPNIVGPRGPRFVVGL 3594
Query: 148 --GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGT-LQFNTV 204
G +V L C E PAP+ TW +DGI L E+ ++T + G LQ +
Sbjct: 3595 APGQLV-LECS-VEAEPAPKITWHRDGIVLQED----------AHTQFPERGRFLQLQAL 3642
Query: 205 SKLDTGEYSCEARNSVG 221
S D+G+YSC ARN+ G
Sbjct: 3643 STADSGDYSCTARNAAG 3659
Score = 48.9 bits (115), Expect = 5e-06
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+RI D G+Y+C +P+ Q + L V P + + + +V
Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQ----QARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 1520
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
+L C+ + G P P TWFKDG L ST YT + LQ D G
Sbjct: 1521 QLLCEAR-GVPTPNITWFKDGALL-------PTSTKVVYTRGGR--QLQLGRAQSSDAGV 1570
Query: 212 YSCEARNSVG 221
Y+C+A N+VG
Sbjct: 1571 YTCKASNAVG 1580
Score = 48.9 bits (115), Expect = 5e-06
Identities = 50/184 (27%), Positives = 73/184 (39%), Gaps = 26/184 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
++ E A L CK + + + W K G+ VS + T+Q + + +K
Sbjct: 4047 LSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---------LLVK 4096
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
N+ DAG Y C +E V L +LV P + S G + LRC
Sbjct: 4097 NLEGQDAGTYTCT----AENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 4152
Query: 158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
+ G+P P W + + E + Q S TLQ VS+ D+G Y C A
Sbjct: 4153 R-GSPTPRIGWTVNDRPVTEG--VSEQDGGS---------TLQRAAVSREDSGTYVCWAE 4200
Query: 218 NSVG 221
N VG
Sbjct: 4201 NRVG 4204
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+++ D+G Y C S + + + ++EVLV P++ + ++ L G
Sbjct: 2408 LKMTQTQEQDSGLYSCLASNEAGEARR----NFSVEVLVPPSIENEDLEEVIKVLDGQTA 2463
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C + G+P P+ TWFKDG L + ++ ++ LQ + G
Sbjct: 2464 HLMC-NVTGHPQPKLTWFKDGRPL---------ARGDAHHISPDGVLLQVLQANLSSAGH 2513
Query: 212 YSCEARNSVG 221
YSC A N+VG
Sbjct: 2514 YSCIAANAVG 2523
Score = 45.8 bits (107), Expect = 5e-05
Identities = 38/131 (29%), Positives = 55/131 (41%), Gaps = 15/131 (11%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTV 150
++ + SDAG+YRCE S ++ V L VL P + E ++G
Sbjct: 1168 SVHFAAIRTSDAGRYRCEAS----NSAGVDAWEVELRVLEPPHWGADETSGLLERVAGEN 1223
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
L C + G P P+ TW K P G + G+L +VS D+G
Sbjct: 1224 ASLPCPAR-GTPKPQVTWRKGPS---SEPLHGQPGVAV-----LEEGSLFLASVSPADSG 1274
Query: 211 EYSCEARNSVG 221
+Y C+A N VG
Sbjct: 1275 DYECQATNEVG 1285
Score = 45.4 bits (106), Expect = 6e-05
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 14/130 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSS--ALSGTVV 151
+++ + + AG Y C +E Q + VLVAP + S V L G V
Sbjct: 3180 LQLSRLQPAQAGTYTCV----AENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV 3235
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C+ +G P P+ W KDG L Q G+L + D G
Sbjct: 3236 RLDCE-ADGQPPPDVAWLKDGSPL-------GQDMGPHLRFYLDGGSLVLKGLRASDAGA 3287
Query: 212 YSCEARNSVG 221
Y+C A N G
Sbjct: 3288 YTCVAHNPAG 3297
Score = 45.1 bits (105), Expect = 8e-05
Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 17/134 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV---PSCEVPSSALSGTV 150
+RI+ SDAG YRC S + E L V V P + PS +P L T
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVA----GSTELRYGLRVNVPPRITLPPS--LPGPVLVNTP 1994
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C + G P+P W KDG NP + + + TL S D+G
Sbjct: 1995 VRLTC-NATGAPSPTLMWLKDG-----NPVSPAGTPGLQVFPGGRVLTLASARAS--DSG 2046
Query: 211 EYSCEARNSVGYRR 224
YSC A ++VG R
Sbjct: 2047 RYSCVAVSAVGEDR 2060
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 18/130 (13%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I+ V D G Y C +A + G++ E V L+VLV P + V + L V L
Sbjct: 1850 LQIEKVDLRDEGIYTC--AATNLAGESKRE--VALKVLVPPNIEPGPVNKAVLENASVTL 1905
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNS--SYTMNTKTGTLQFNTVSKLDTGE 211
C G P P+ +WFK G Q +S T++ L+ D G
Sbjct: 1906 ECL-ASGVPPPDVSWFK-----------GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 1953
Query: 212 YSCEARNSVG 221
Y C A N G
Sbjct: 1954 YRCVASNVAG 1963
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 17/129 (13%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL---SGTVVE 152
+K + SDAG Y C P+ + L T+ VLV P + S L G +V
Sbjct: 3277 LKGLRASDAGAYTCVAHNPAGEDARLH----TVNVLVPPTIKQGADGSGTLVSRPGELVT 3332
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+ C + G+P +W KDG+ L + R ++ TL+ + V D G +
Sbjct: 3333 MVCPVR-GSPPIHVSWLKDGLPLPLSQRT---------LLHGSGHTLRISKVQLADAGIF 3382
Query: 213 SCEARNSVG 221
+C A + G
Sbjct: 3383 TCVAASPAG 3391
Score = 42.4 bits (98), Expect = 5e-04
Identities = 50/203 (24%), Positives = 88/203 (43%), Gaps = 26/203 (12%)
Query: 29 FSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAE 88
+ A + ++ V + A L C + T ++ W+K G S ++ Q + A
Sbjct: 1207 WGADETSGLLERVAGENASLPCPA-RGTPKPQVTWRK-GPSSEPLHGQPGV-------AV 1257
Query: 89 MIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV--PSCEVPSSAL 146
+ + ++ + +V+ +D+G Y C+ A +E G L V V P++ + S +
Sbjct: 1258 LEEGSLFLASVSPADSGDYECQ--ATNEVGSTSRR--AKLVVYVPPSIREDGRKANVSGM 1313
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTN--------SSYTMNTKTGT 198
+G + L C D G P PE W KD +L+ P LG + + + +
Sbjct: 1314 AGQSLTLEC-DANGFPVPEIVWLKDA-QLVGVP-LGWAGYGWDLGWGQVGGHRLLDEGQS 1370
Query: 199 LQFNTVSKLDTGEYSCEARNSVG 221
L F + + D+G YSC A N G
Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAG 1393
Score = 41.6 bits (96), Expect = 9e-04
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 14/132 (10%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D ++ + + AG+Y C V+ + Q+ + V L V V P + G
Sbjct: 937 DGSLHLDRALQEHAGRYSC-VATNTAGSQHRD---VELVVQVPPRIHPTATHHITNEGVP 992
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
L C G PAP TW K+ L S Y ++ K GTL S D G
Sbjct: 993 ASLPCV-ASGVPAPTITWTKETNALT--------SRGPHYNVS-KEGTLLIAQPSAQDAG 1042
Query: 211 EYSCEARNSVGY 222
Y C A N+VG+
Sbjct: 1043 AYVCTATNTVGF 1054
Score = 41.6 bits (96), Expect = 9e-04
Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSC---EVPSSALSGTV 150
+++ SDAG Y C+ S E L+V V P + A++G
Sbjct: 1558 LQLGRAQSSDAGVYTCKAS----NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRP 1613
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C + G+P+P +W +G+ + E ++ + T L+ + + +G
Sbjct: 1614 VALECVAR-GHPSPTLSWHHEGLPVAE---------SNESRLETDGSVLRLESPGEASSG 1663
Query: 211 EYSCEARNSVG 221
YSC A + G
Sbjct: 1664 LYSCVASSPAG 1674
Score = 41.6 bits (96), Expect = 9e-04
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 94 IRIKNVTRSDAGKYRCEVSAP-SEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
++I V +AG+Y C+ S E + E +T V++ E + S TV
Sbjct: 2806 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTV-S 2864
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L+C GNP P +W ++G+ +PRL LQ +T D Y
Sbjct: 2865 LQCPAL-GNPVPTISWLQNGLPFSPSPRLQVLEDGQ---------VLQVSTAEVADAASY 2914
Query: 213 SCEARNSVG 221
C A N G
Sbjct: 2915 MCVAENQAG 2923
Score = 41.6 bits (96), Expect = 9e-04
Identities = 46/188 (24%), Positives = 76/188 (40%), Gaps = 30/188 (15%)
Query: 38 VTAVEYQEAILACK---TPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
+T + A+L C+ +PK V W K G+ + F + QG ++ ++ N
Sbjct: 3773 LTLTAHTPALLPCEASGSPKPLVV----WWKDGQKLDF----RLQQGAYR----LLPSNA 3820
Query: 95 RIKNVTR-SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ D+ ++ C VS + L + TV V P + + + V L
Sbjct: 3821 LLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----VPPTIADDQTDFTVTMMAPVVL 3876
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C G PAP +W K G +L + S Y ++ +G L+ + G Y+
Sbjct: 3877 TCHST-GIPAPTVSWSKAGAQL--------GARGSGYRVSP-SGALEIGQALPIHAGRYT 3926
Query: 214 CEARNSVG 221
C ARNS G
Sbjct: 3927 CSARNSAG 3934
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 10/129 (7%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+RI DAG Y C A +E G E + L V AP + + G L
Sbjct: 750 LRIPAAQERDAGTYTCR--AVNELGDASAE--IQLAVGHAPQLTELPRDVTVELGRSALL 805
Query: 154 RCQDKEGNPAPEYTWFK-DGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
C+ G P P TW + DG L RLG+ S + +G L F +V+ D Y
Sbjct: 806 ACR-ATGRPPPTVTWRRGDGQPL--GLRLGAG--RGSRSRQPDSGVLFFESVAPEDQAPY 860
Query: 213 SCEARNSVG 221
CEARN G
Sbjct: 861 VCEARNVFG 869
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/190 (22%), Positives = 73/190 (38%), Gaps = 25/190 (13%)
Query: 35 QQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
++V+ ++ Q A L C +L W K GR ++ +GD + +
Sbjct: 2452 EEVIKVLDGQTAHLMCNVTGHP-QPKLTWFKDGRPLA--------RGD-AHHISPDGVLL 2501
Query: 95 RIKNVTRSDAGKYRC-EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++ S AG Y C +A E+ ++ + + ++ A S + + + L
Sbjct: 2502 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISL 2561
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGT--LQFNTVSKLDTGE 211
C+ P+P TW KDG +S + GT LQ K D G+
Sbjct: 2562 ICEAL-AFPSPNITWMKDGAPF-----------EASRNIQLLPGTHGLQILNAQKEDAGQ 2609
Query: 212 YSCEARNSVG 221
Y+C N +G
Sbjct: 2610 YTCVVTNELG 2619
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 12/125 (9%)
Query: 97 KNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQ 156
++V D Y CE A + G+ E + + P + S L G V L C
Sbjct: 850 ESVAPEDQAPYVCE--ARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCI 907
Query: 157 DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
G P PE W KDG L R ++ G+L + + G YSC A
Sbjct: 908 VLAGRPLPERHWLKDGRPLPPGSRHSIRA----------DGSLHLDRALQEHAGRYSCVA 957
Query: 217 RNSVG 221
N+ G
Sbjct: 958 TNTAG 962
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 21/135 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV----PSCEVPSSALSGT 149
++I N + DAG+Y C V+ +E G+ ++ V EVL+ P++ P EV +
Sbjct: 2597 LQILNAQKEDAGQYTCVVT--NELGEAVKNYHV--EVLIPPSISKDDPLGEVGVKEVKTK 2652
Query: 150 V---VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
V + L C+ P P W+KDG + + RL + + LQ
Sbjct: 2653 VNSTLTLECESW-AVPPPTIRWYKDGQPVTPSSRL---------QVLGEGRLLQIQPTQV 2702
Query: 207 LDTGEYSCEARNSVG 221
D+G Y C A N G
Sbjct: 2703 SDSGRYLCVATNVAG 2717
Score = 39.7 bits (91), Expect = 0.003
Identities = 40/133 (30%), Positives = 56/133 (42%), Gaps = 27/133 (20%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTV 150
+++++ V D+G Y C A SE G+ +T V+ P + P+ S G
Sbjct: 3457 SLQLEAVGAGDSGTYSCV--AVSEAGEARRHFQLT--VMEPPHIEDSGQPTELSLTPGAP 3512
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRL--LENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
+EL C D +G P P TW KDG L LEN NS T + D
Sbjct: 3513 MELLC-DAQGTPQPNITWHKDGQALTRLEN--------NSRAT----------RVLRVRD 3553
Query: 209 TGEYSCEARNSVG 221
G Y+C A + G
Sbjct: 3554 AGLYTCLAESPAG 3566
Score = 39.7 bits (91), Expect = 0.003
Identities = 44/193 (22%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 32 PKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
P+ + V + + +L C + + ++ W + G + Q+ F R +
Sbjct: 3585 PRGPRFVVGLAPGQLVLECSVEAEP-APKITWHRDG-----IVLQEDAHTQFPERGRFL- 3637
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+++ ++ +D+G Y C +A + G +E+ P + S +
Sbjct: 3638 ---QLQALSTADSGDYSC--TARNAAGST--SVAFRVEIHTVPTIRSGPPAVNVSVNQTA 3690
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L CQ +G PAP +W KD + L +PR S G+L+ V D G
Sbjct: 3691 LLPCQ-ADGVPAPLVSWRKDRVPL--DPR-------SPRFEILPEGSLRIQPVLAQDAGH 3740
Query: 212 YSCEARNSVGYRR 224
Y C A NS G R
Sbjct: 3741 YLCLASNSAGSDR 3753
Score = 38.5 bits (88), Expect = 0.007
Identities = 39/121 (32%), Positives = 55/121 (45%), Gaps = 15/121 (12%)
Query: 103 DAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL-SGTVVELRCQDKEGN 161
DAG Y CE A ++ G + E L V VAP P E + + G L C+ + G
Sbjct: 2135 DAGHYTCE--ALNQAGHS--EKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR-GV 2189
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL-DTGEYSCEARNSV 220
P P+ +W KDG + L G Q ++ G L + ++L G Y+CE N V
Sbjct: 2190 PFPKISWRKDG-QPLPGEGAGLQHVSA-------VGRLLYLGQAQLAQEGTYTCECSNVV 2241
Query: 221 G 221
G
Sbjct: 2242 G 2242
Score = 37.0 bits (84), Expect = 0.021
Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 18/125 (14%)
Query: 99 VTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS--GTVVELRCQ 156
V+R D+G Y C +E + + V AP + E S + G ++L C
Sbjct: 4187 VSREDSGTYVCW----AENRVGRTQAVSFVHVKEAPVLQG-EAFSYLVEPVGGSIQLDCV 4241
Query: 157 DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
+ G+P P+ W KDG+ L S + G+L + + D G Y C A
Sbjct: 4242 VR-GDPVPDIHWIKDGLPL----------RGSHLRHQLQNGSLTIHRTERDDAGRYQCLA 4290
Query: 217 RNSVG 221
N +G
Sbjct: 4291 ENEMG 4295
Score = 28.1 bits (61), Expect = 9.8
Identities = 42/190 (22%), Positives = 72/190 (37%), Gaps = 27/190 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
V+ V+ A L C K + + W++ G+ V L +N+ + ++ ++
Sbjct: 2268 VSVVQDGVATLECNATGKPPPT-VTWERDGQPVG-----AELGLQLQNQGQ----SLHVE 2317
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV---VELR 154
+ G+Y C +E E L VLV P + P + ++ + + L
Sbjct: 2318 RAQAAHTGRYSCV----AENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 2373
Query: 155 CQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSC 214
C+ G P P WF+ E P + T + L+ + D+G YSC
Sbjct: 2374 CEAM-GIPPPAIRWFRG-----EEPVSPGEDTY----LLAGGWMLKMTQTQEQDSGLYSC 2423
Query: 215 EARNSVGYRR 224
A N G R
Sbjct: 2424 LASNEAGEAR 2433
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 59.3 bits (142), Expect = 4e-09
Identities = 57/193 (29%), Positives = 85/193 (44%), Gaps = 35/193 (18%)
Query: 37 VVTAVEYQEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFN 93
VV AV +E +L C+ P+ T++ W+K G +V+ Q L G
Sbjct: 2674 VVRAVAEEEVLLPCEASGIPRPTIT----WQKEGLNVATGVSTQVLPGG----------Q 2719
Query: 94 IRIKNVTRSDAGKYRC--EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+RI + + DAG Y C + SA S G+ L V V P + + S G+
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKT------RLVVQVPPVIENGLPDLSTTEGSHA 2773
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C+ + G+P P TW KDG P G++ +T+ +G L + D G
Sbjct: 2774 FLPCKAR-GSPEPNITWDKDG-----QPVSGAEG---KFTIQP-SGELLVKNLEGQDAGT 2823
Query: 212 YSCEARNSVGYRR 224
Y+C A N+VG R
Sbjct: 2824 YTCTAENAVGRAR 2836
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 30/193 (15%)
Query: 31 APKDQQVVTAVEY-QEAILACKT---PKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNR 86
AP+ Q V +A+L+C+T P+ TV+ W K G+ + Q L+G +
Sbjct: 1752 APRGPQDAVLVRVGDKAVLSCETDALPEPTVT----WYKDGQPLVLAQRTQALRGGQR-- 1805
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL 146
+ I+ SD G Y C+VS + G+ + T+T++V P E S +
Sbjct: 1806 -------LEIQEAQVSDKGLYSCKVS--NVAGEAVRTFTLTVQVPPTFENPKTETVSQ-V 1855
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
+G+ + L C D G PAP TW KD + + +++ + + ++ G LQ + +
Sbjct: 1856 AGSPLVLTC-DVSGVPAPTVTWLKDRMPV---------ESSAVHGVVSRGGRLQLSRLQP 1905
Query: 207 LDTGEYSCEARNS 219
G Y+C A N+
Sbjct: 1906 AQAGTYTCVAENT 1918
Score = 53.9 bits (128), Expect = 2e-07
Identities = 42/130 (32%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRC-EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
+ + + SD+G+Y C VSA E Q+ V L+V + P++ E+ S ++ V
Sbjct: 753 LTLASARASDSGRYSCVAVSAVGEDRQD-----VVLQVHMPPSILGEELNVSVVANESVA 807
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L CQ P P +W+KDG R LE PR G ++ LQ + D G Y
Sbjct: 808 LECQS-HAMPPPVLSWWKDG-RPLE-PRPGVH-------LSADKALLQVDRADVWDAGHY 857
Query: 213 SCEARNSVGY 222
+CEA N G+
Sbjct: 858 TCEALNQAGH 867
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 20/133 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL--SGTVV 151
+RI V +DAG + C ++P+ + + TL+V V P + E + + G++V
Sbjct: 2087 LRISKVQLADAGIFTCVAASPA----GVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLV 2142
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
EL C+ + G P P +W KDG LL SQS +LQ V D+G
Sbjct: 2143 ELPCEAR-GVPLPLVSWMKDGEPLL------SQSLEQG-------PSLQLEAVGAGDSGT 2188
Query: 212 YSCEARNSVGYRR 224
YSC A + G R
Sbjct: 2189 YSCVAVSEAGEAR 2201
Score = 52.0 bits (123), Expect = 6e-07
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
Query: 86 RAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSA 145
R ++ + ++ I+ R DAG+Y+C A +E G + + V L + AP +
Sbjct: 2983 RHQLQNGSLTIRRTERDDAGRYQC--LAENEMG--VAKKVVILVLQSAPVFQVEPQDMTV 3038
Query: 146 LSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVS 205
SG V LRCQ G P P W + G L + RL + S + N +TG
Sbjct: 3039 RSGDDVALRCQ-ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETG-------- 3089
Query: 206 KLDTGEYSCEARNSVG 221
D G Y C A N +G
Sbjct: 3090 --DAGTYDCVAHNLLG 3103
Score = 49.7 bits (117), Expect = 3e-06
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 15/129 (11%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS-SALSGTVVE 152
+++ +DA Y C +E E TL V V P + ++ +A+ + V
Sbjct: 1619 LQVSTAEVADAASYMCV----AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVS 1674
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C D +P PE TW+KD L S + T TLQ D+G Y
Sbjct: 1675 LPC-DVHAHPNPEVTWYKDSQAL---------SLGEEVFLLPGTHTLQLGRARLSDSGMY 1724
Query: 213 SCEARNSVG 221
+CEA N+ G
Sbjct: 1725 TCEALNAAG 1733
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 21/137 (15%)
Query: 90 IDFNIRIKNVTR-SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS- 147
++ N R V R DAG Y C +P+ E + + V P + P +
Sbjct: 2257 LENNSRATRVLRVRDAGLYTCLAESPA----GAIEKSFRVRVQAPPNIVGPRGPRFVVGL 2312
Query: 148 --GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGT-LQFNTV 204
G +V L C E PAP+ TW +DGI L E+ ++T + G LQ +
Sbjct: 2313 APGQLV-LECS-VEAEPAPKITWHRDGIVLQED----------AHTQFPERGRFLQLQAL 2360
Query: 205 SKLDTGEYSCEARNSVG 221
S D+G+YSC ARN+ G
Sbjct: 2361 STADSGDYSCTARNAAG 2377
Score = 48.9 bits (115), Expect = 5e-06
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+RI D G+Y+C +P+ Q + L V P + + + +V
Sbjct: 183 LRITGSHVGDEGRYQCVAFSPAGQ----QARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 238
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
+L C+ + G P P TWFKDG L ST YT + LQ D G
Sbjct: 239 QLLCEAR-GVPTPNITWFKDGALL-------PTSTKVVYTRGGR--QLQLGRAQSSDAGV 288
Query: 212 YSCEARNSVG 221
Y+C+A N+VG
Sbjct: 289 YTCKASNAVG 298
Score = 48.9 bits (115), Expect = 5e-06
Identities = 50/184 (27%), Positives = 73/184 (39%), Gaps = 26/184 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
++ E A L CK + + + W K G+ VS + T+Q + + +K
Sbjct: 2765 LSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---------LLVK 2814
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
N+ DAG Y C +E V L +LV P + S G + LRC
Sbjct: 2815 NLEGQDAGTYTCT----AENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 2870
Query: 158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEAR 217
+ G+P P W + + E + Q S TLQ VS+ D+G Y C A
Sbjct: 2871 R-GSPTPRIGWTVNDRPVTEG--VSEQDGGS---------TLQRAAVSREDSGTYVCWAE 2918
Query: 218 NSVG 221
N VG
Sbjct: 2919 NRVG 2922
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 16/130 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTVV 151
+++ D+G Y C S + + + ++EVLV P++ + ++ L G
Sbjct: 1126 LKMTQTQEQDSGLYSCLASNEAGEARR----NFSVEVLVPPSIENEDLEEVIKVLDGQTA 1181
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C + G+P P+ TWFKDG L + ++ ++ LQ + G
Sbjct: 1182 HLMC-NVTGHPQPKLTWFKDGRPL---------ARGDAHHISPDGVLLQVLQANLSSAGH 1231
Query: 212 YSCEARNSVG 221
YSC A N+VG
Sbjct: 1232 YSCIAANAVG 1241
Score = 45.4 bits (106), Expect = 6e-05
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 14/130 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSS--ALSGTVV 151
+++ + + AG Y C +E Q + VLVAP + S V L G V
Sbjct: 1898 LQLSRLQPAQAGTYTCV----AENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV 1953
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L C+ +G P P+ W KDG L Q G+L + D G
Sbjct: 1954 RLDCE-ADGQPPPDVAWLKDGSPL-------GQDMGPHLRFYLDGGSLVLKGLRASDAGA 2005
Query: 212 YSCEARNSVG 221
Y+C A N G
Sbjct: 2006 YTCVAHNPAG 2015
Score = 45.1 bits (105), Expect = 8e-05
Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 17/134 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV---PSCEVPSSALSGTV 150
+RI+ SDAG YRC S + E L V V P + PS +P L T
Sbjct: 659 LRIEQAQLSDAGSYRCVASNVA----GSTELRYGLRVNVPPRITLPPS--LPGPVLVNTP 712
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C + G P+P W KDG NP + + + TL S D+G
Sbjct: 713 VRLTC-NATGAPSPTLMWLKDG-----NPVSPAGTPGLQVFPGGRVLTLASARAS--DSG 764
Query: 211 EYSCEARNSVGYRR 224
YSC A ++VG R
Sbjct: 765 RYSCVAVSAVGEDR 778
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 18/130 (13%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++I+ V D G Y C +A + G++ E V L+VLV P + V + L V L
Sbjct: 568 LQIEKVDLRDEGIYTC--AATNLAGESKRE--VALKVLVPPNIEPGPVNKAVLENASVTL 623
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNS--SYTMNTKTGTLQFNTVSKLDTGE 211
C G P P+ +WFK G Q +S T++ L+ D G
Sbjct: 624 ECL-ASGVPPPDVSWFK-----------GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 671
Query: 212 YSCEARNSVG 221
Y C A N G
Sbjct: 672 YRCVASNVAG 681
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 17/129 (13%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL---SGTVVE 152
+K + SDAG Y C P+ + L T+ VLV P + S L G +V
Sbjct: 1995 LKGLRASDAGAYTCVAHNPAGEDARLH----TVNVLVPPTIKQGADGSGTLVSRPGELVT 2050
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+ C + G+P +W KDG+ L + R ++ TL+ + V D G +
Sbjct: 2051 MVCPVR-GSPPIHVSWLKDGLPLPLSQRT---------LLHGSGHTLRISKVQLADAGIF 2100
Query: 213 SCEARNSVG 221
+C A + G
Sbjct: 2101 TCVAASPAG 2109
Score = 41.6 bits (96), Expect = 9e-04
Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSC---EVPSSALSGTV 150
+++ SDAG Y C+ S E L+V V P + A++G
Sbjct: 276 LQLGRAQSSDAGVYTCKAS----NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRP 331
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V L C + G+P+P +W +G+ + E ++ + T L+ + + +G
Sbjct: 332 VALECVAR-GHPSPTLSWHHEGLPVAE---------SNESRLETDGSVLRLESPGEASSG 381
Query: 211 EYSCEARNSVG 221
YSC A + G
Sbjct: 382 LYSCVASSPAG 392
Score = 41.6 bits (96), Expect = 9e-04
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 94 IRIKNVTRSDAGKYRCEVSAP-SEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
++I V +AG+Y C+ S E + E +T V++ E + S TV
Sbjct: 1524 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTV-S 1582
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L+C GNP P +W ++G+ +PRL LQ +T D Y
Sbjct: 1583 LQCPAL-GNPVPTISWLQNGLPFSPSPRLQVLEDGQ---------VLQVSTAEVADAASY 1632
Query: 213 SCEARNSVG 221
C A N G
Sbjct: 1633 MCVAENQAG 1641
Score = 41.6 bits (96), Expect = 9e-04
Identities = 46/188 (24%), Positives = 76/188 (40%), Gaps = 30/188 (15%)
Query: 38 VTAVEYQEAILACK---TPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
+T + A+L C+ +PK V W K G+ + F + QG ++ ++ N
Sbjct: 2491 LTLTAHTPALLPCEASGSPKPLVV----WWKDGQKLDF----RLQQGAYR----LLPSNA 2538
Query: 95 RIKNVTR-SDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+ D+ ++ C VS + L + TV V P + + + V L
Sbjct: 2539 LLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----VPPTIADDQTDFTVTMMAPVVL 2594
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C G PAP +W K G +L + S Y ++ +G L+ + G Y+
Sbjct: 2595 TCHST-GIPAPTVSWSKAGAQL--------GARGSGYRVSP-SGALEIGQALPIHAGRYT 2644
Query: 214 CEARNSVG 221
C ARNS G
Sbjct: 2645 CSARNSAG 2652
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 21/135 (15%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAV----PSCEVPSSALSGT 149
++I N + DAG+Y C V+ +E G+ ++ V EVL+ P++ P EV +
Sbjct: 1315 LQILNAQKEDAGQYTCVVT--NELGEAVKNYHV--EVLIPPSISKDDPLAEVGVKEVKTK 1370
Query: 150 V---VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
V + L C+ P P W+KDG + + RL + + LQ
Sbjct: 1371 VNSTLTLECESW-AVPPPTIRWYKDGQPVTPSSRL---------QVLGEGRLLQIQPTQV 1420
Query: 207 LDTGEYSCEARNSVG 221
D+G Y C A N G
Sbjct: 1421 SDSGRYLCVATNVAG 1435
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/190 (22%), Positives = 73/190 (38%), Gaps = 25/190 (13%)
Query: 35 QQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNI 94
++V+ ++ Q A L C +L W K GR ++ +GD + +
Sbjct: 1170 EEVIKVLDGQTAHLMCNVTGHP-QPKLTWFKDGRPLA--------RGD-AHHISPDGVLL 1219
Query: 95 RIKNVTRSDAGKYRC-EVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
++ S AG Y C +A E+ ++ + + ++ A S + + + L
Sbjct: 1220 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISL 1279
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGT--LQFNTVSKLDTGE 211
C+ P+P TW KDG +S + GT LQ K D G+
Sbjct: 1280 ICEAL-AFPSPNITWMKDGAPF-----------EASRNIQLLPGTHGLQILNAQKEDAGQ 1327
Query: 212 YSCEARNSVG 221
Y+C N +G
Sbjct: 1328 YTCVVTNELG 1337
Score = 39.7 bits (91), Expect = 0.003
Identities = 40/133 (30%), Positives = 56/133 (42%), Gaps = 27/133 (20%)
Query: 93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPS--SALSGTV 150
+++++ V D+G Y C A SE G+ +T V+ P + P+ S G
Sbjct: 2175 SLQLEAVGAGDSGTYSCV--AVSEAGEARRHFQLT--VMEPPHIEDSGQPTELSLTPGAP 2230
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRL--LENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
+EL C D +G P P TW KDG L LEN NS T + D
Sbjct: 2231 MELLC-DAQGTPQPNITWHKDGQALTRLEN--------NSRAT----------RVLRVRD 2271
Query: 209 TGEYSCEARNSVG 221
G Y+C A + G
Sbjct: 2272 AGLYTCLAESPAG 2284
Score = 39.7 bits (91), Expect = 0.003
Identities = 44/193 (22%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 32 PKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
P+ + V + + +L C + + ++ W + G + Q+ F R +
Sbjct: 2303 PRGPRFVVGLAPGQLVLECSVEAEP-APKITWHRDG-----IVLQEDAHTQFPERGRFL- 2355
Query: 92 FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
+++ ++ +D+G Y C +A + G +E+ P + S +
Sbjct: 2356 ---QLQALSTADSGDYSC--TARNAAGST--SVAFRVEIHTVPTIRSGPPAVNVSVNQTA 2408
Query: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
L CQ +G PAP +W KD + L +PR S G+L+ V D G
Sbjct: 2409 LLPCQ-ADGVPAPLVSWRKDRVPL--DPR-------SPRFEILPEGSLRIQPVLAQDAGH 2458
Query: 212 YSCEARNSVGYRR 224
Y C A NS G R
Sbjct: 2459 YLCLASNSAGSDR 2471
Score = 38.5 bits (88), Expect = 0.007
Identities = 39/121 (32%), Positives = 55/121 (45%), Gaps = 15/121 (12%)
Query: 103 DAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL-SGTVVELRCQDKEGN 161
DAG Y CE A ++ G + E L V VAP P E + + G L C+ + G
Sbjct: 853 DAGHYTCE--ALNQAGHS--EKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECR-GV 907
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL-DTGEYSCEARNSV 220
P P+ +W KDG + L G Q ++ G L + ++L G Y+CE N V
Sbjct: 908 PFPKISWRKDG-QPLPGEGAGLQHVSA-------VGRLLYLGQAQLAQEGTYTCECSNVV 959
Query: 221 G 221
G
Sbjct: 960 G 960
Score = 36.6 bits (83), Expect = 0.027
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 18/125 (14%)
Query: 99 VTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS--GTVVELRCQ 156
V+R D+G Y C +E + + V AP + E S + G ++L C
Sbjct: 2905 VSREDSGTYVCW----AENRVGRTQAVSFVHVKEAPVLQG-EAFSYLVEPVGGSIQLDCV 2959
Query: 157 DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
+ G+P P+ W KDG+ L S + G+L + D G Y C A
Sbjct: 2960 VR-GDPVPDIHWIKDGLPL----------RGSHLRHQLQNGSLTIRRTERDDAGRYQCLA 3008
Query: 217 RNSVG 221
N +G
Sbjct: 3009 ENEMG 3013
Score = 34.7 bits (78), Expect = 0.10
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 144 SALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTN--------SSYTMNTK 195
S ++G + L C D G P PE W KD +L+ P LG + + +
Sbjct: 29 SGMAGQSLTLEC-DANGFPVPEIVWLKDA-QLVGVP-LGWAGYGWDLGWGQVGGHRLLDE 85
Query: 196 TGTLQFNTVSKLDTGEYSCEARNSVG 221
+L F + + D+G YSC A N G
Sbjct: 86 GQSLHFPRIQEGDSGLYSCRAENQAG 111
Score = 28.1 bits (61), Expect = 9.8
Identities = 42/190 (22%), Positives = 72/190 (37%), Gaps = 27/190 (14%)
Query: 38 VTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK 97
V+ V+ A L C K + + W++ G+ V L +N+ + ++ ++
Sbjct: 986 VSVVQDGVATLECNATGKPPPT-VTWERDGQPVG-----AELGLQLQNQGQ----SLHVE 1035
Query: 98 NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV---VELR 154
+ G+Y C +E E L VLV P + P + ++ + + L
Sbjct: 1036 RAQAAHTGRYSCV----AENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 1091
Query: 155 CQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSC 214
C+ G P P WF+ E P + T + L+ + D+G YSC
Sbjct: 1092 CEAM-GIPPPAIRWFRG-----EEPVSPGEDTY----LLAGGWMLKMTQTQEQDSGLYSC 1141
Query: 215 EARNSVGYRR 224
A N G R
Sbjct: 1142 LASNEAGEAR 1151
>gi|54792136 follistatin-like 4 [Homo sapiens]
Length = 842
Score = 58.5 bits (140), Expect = 7e-09
Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 20/191 (10%)
Query: 31 APKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMI 90
AP+D+ VT V + + + + WK+ G +++F+ + DF
Sbjct: 250 APEDRVSVTTVTVGLSTVLTCAVHGDLRPPIIWKRNGLTLNFLDLEDI--NDFGE----- 302
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D ++ I VT G Y C S + Q T L+V V P + + G
Sbjct: 303 DDSLYITKVTTIHMGNYTCHASGHEQLFQ-----THVLQVNVPPVIRVYPESQAQEPGVA 357
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
LRC EG P P TW K+G+ + S + ++ L ++V DTG
Sbjct: 358 ASLRCH-AEGIPMPRITWLKNGVDV-------STQMSKQLSLLANGSELHISSVRYEDTG 409
Query: 211 EYSCEARNSVG 221
Y+C A+N VG
Sbjct: 410 AYTCIAKNEVG 420
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 58.5 bits (140), Expect = 7e-09
Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 23/179 (12%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D +I + N+ SD Y C V + + V + V PAVP C G
Sbjct: 108 DASINLMNLQVSDTATYECRVKKTT-----MATRKVIVTVQARPAVPMCWTEGHMTYGND 162
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENP-RLGS--------------QSTNSSYTMNTK 195
V L+C G+ Y W K I P R GS +S +SS
Sbjct: 163 VVLKCYASGGSQPLSYKWAK--ISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLN 220
Query: 196 TGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVC 254
G L +S+ D G Y C N+VGY C ++V D G+I +V+ +L+ C
Sbjct: 221 NGDLVLKDISRADDGLYQCTVANNVGYSVCV-VEVKVSDSRRIGVIIGIVLGSLLALGC 278
>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
Length = 844
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/74 (41%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G L+C+ GNP P Y WFKDG L S+ Y K LQFN V
Sbjct: 250 GEKQSLKCEAAAGNPQPSYRWFKDGKELNR-----SRDIRIKYGNGRKNSRLQFNKVKVE 304
Query: 208 DTGEYSCEARNSVG 221
D GEY CEA N +G
Sbjct: 305 DAGEYVCEAENILG 318
>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
Length = 852
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/74 (41%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G L+C+ GNP P Y WFKDG L S+ Y K LQFN V
Sbjct: 250 GEKQSLKCEAAAGNPQPSYRWFKDGKELNR-----SRDIRIKYGNGRKNSRLQFNKVKVE 304
Query: 208 DTGEYSCEARNSVG 221
D GEY CEA N +G
Sbjct: 305 DAGEYVCEAENILG 318
>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
Length = 858
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/74 (41%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G L+C+ GNP P Y WFKDG L S+ Y K LQFN V
Sbjct: 250 GEKQSLKCEAAAGNPQPSYRWFKDGKELNR-----SRDIRIKYGNGRKNSRLQFNKVKVE 304
Query: 208 DTGEYSCEARNSVG 221
D GEY CEA N +G
Sbjct: 305 DAGEYVCEAENILG 318
>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
Length = 850
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/74 (41%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G L+C+ GNP P Y WFKDG L S+ Y K LQFN V
Sbjct: 250 GEKQSLKCEAAAGNPQPSYRWFKDGKELNR-----SRDIRIKYGNGRKNSRLQFNKVKVE 304
Query: 208 DTGEYSCEARNSVG 221
D GEY CEA N +G
Sbjct: 305 DAGEYVCEAENILG 318
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 57.8 bits (138), Expect = 1e-08
Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 13/128 (10%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+RI V D G+Y C+ A + G +T++ V P S ++ G V+L
Sbjct: 487 LRISGVALHDQGQYECQ--AVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQL 544
Query: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYS 213
C +G P P TW KDG+++ E+ + + G L N V D G Y
Sbjct: 545 PCSS-QGEPEPAITWNKDGVQVTESGKFHI----------SPEGFLTINDVGPADAGRYE 593
Query: 214 CEARNSVG 221
C ARN++G
Sbjct: 594 CVARNTIG 601
Score = 52.8 bits (125), Expect = 4e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 21/132 (15%)
Query: 96 IKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSS---ALSGTVVE 152
I+NV + D+G+Y C + N++ T ++V A+P V + G V+
Sbjct: 399 IQNVVQGDSGEYACSAT------NNIDSVHATAFIIVQ-ALPQFTVTPQDRVVIEGQTVD 451
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
+C+ K GNP P W K G +L + R + +GTL+ + V+ D G+Y
Sbjct: 452 FQCEAK-GNPPPVIAWTKGGSQLSVDRR----------HLVLSSGTLRISGVALHDQGQY 500
Query: 213 SCEARNSVGYRR 224
C+A N +G ++
Sbjct: 501 ECQAVNIIGSQK 512
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 18/134 (13%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVP---SSALS 147
D + I+N +D G Y+C A + G+ ++ VTL +PA P+ + + L
Sbjct: 299 DGTLMIQNTQETDQGIYQC--MAKNVAGE-VKTQEVTLRYFGSPARPTFVIQPQNTEVLV 355
Query: 148 GTVVELRCQDKEGNPAPEYTWFK-DGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
G V L C G+P P +W + D L +PR+ + Y N G
Sbjct: 356 GESVTLECS-ATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQG--------- 405
Query: 207 LDTGEYSCEARNSV 220
D+GEY+C A N++
Sbjct: 406 -DSGEYACSATNNI 418
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 125 TVTLEVLVA--PAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLG 182
T+T E L P + S + SG V C+ EGNP PE W ++ L
Sbjct: 235 TITPEELNCERPRITSEPQDADVTSGNTVYFTCR-AEGNPKPEIIWLRNNNEL------- 286
Query: 183 SQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
S T+S + GTL + D G Y C A+N G
Sbjct: 287 SMKTDSRLNL-LDDGTLMIQNTQETDQGIYQCMAKNVAG 324
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 55.8 bits (133), Expect = 4e-08
Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 32/168 (19%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSA--LSG 148
+ + + +V R+DAG Y CE+ P+ ++ D VTL VL P P+ PS A G
Sbjct: 197 NMTLTLLSVKRNDAGSYECEIQNPASANRS---DPVTLNVLYGPDGPTIS-PSKANYRPG 252
Query: 149 TVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLD 208
+ L C NP +Y+WF +G T T L ++ +
Sbjct: 253 ENLNLSCH-AASNPPAQYSWFING------------------TFQQSTQELFIPNITVNN 293
Query: 209 TGEYSCEARNSVGYRRCPGKRMQVDDLNISG---IIAAVVVVALVISV 253
+G Y C+A NS R V + +SG +++AV V + I V
Sbjct: 294 SGSYMCQAHNSA----TGLNRTTVTMITVSGSAPVLSAVATVGITIGV 337
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/155 (25%), Positives = 64/155 (41%), Gaps = 22/155 (14%)
Query: 76 QQTLQGDFKNRAEMI--DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVA 133
QQ G + E I + ++ I+NVT++D G Y +V +L + T + V
Sbjct: 87 QQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIK-----SDLVNEEATGQFHVY 141
Query: 134 PAVPSCEVPSSALSGT----VVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSS 189
P +P + S+ + V C+ + N Y W+ +G L +PRL + N
Sbjct: 142 PELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT--YLWWVNGQSLPVSPRLQLSNGNM- 198
Query: 190 YTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRR 224
TL +V + D G Y CE +N R
Sbjct: 199 --------TLTLLSVKRNDAGSYECEIQNPASANR 225
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 55.5 bits (132), Expect = 6e-08
Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 15/160 (9%)
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL 146
A++ D ++ I + +D G+Y+C S + +V L V AP V
Sbjct: 448 AQLADLSLEISGIIPTDGGRYQCVAS----NANGVTRASVWLLVREAPQVSIHTSSQHFS 503
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
G V++ C G P P +W ++ L E+ R+ + GTL V+
Sbjct: 504 QGVEVKVSCS-ASGYPTPHISWSRESQALQEDSRIHVDAQ----------GTLIIQGVAP 552
Query: 207 LDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVV 246
D G YSC+A N VG + D ++S + A V+V
Sbjct: 553 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 592
Score = 50.1 bits (118), Expect = 2e-06
Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 18/152 (11%)
Query: 70 VSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLE 129
+S+ Q LQ D + + + I+ V DAG Y C+ A +E G +++TVTL
Sbjct: 522 ISWSRESQALQEDSRIHVDA-QGTLIIQGVAPEDAGNYSCQ--ATNEVGT--DQETVTLY 576
Query: 130 VLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSS 189
P+V + G L C+ G P P W++ G+ ++ P GS S
Sbjct: 577 YTDPPSVSAVNAVVLVAVGEEAVLVCE-ASGVPPPRVIWYRGGLEMILAPE-GSSS---- 630
Query: 190 YTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
G L+ + D G Y+C A N +G
Sbjct: 631 -------GKLRIPAAQERDAGTYTCRAVNELG 655
Score = 41.6 bits (96), Expect = 9e-04
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 14/132 (10%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D ++ + + AG+Y C V+ + Q+ + V L V V P + G
Sbjct: 820 DGSLHLDRALQEHAGRYSC-VATNTAGSQHRD---VELVVQVPPRIHPTATHHITNEGVP 875
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
L C G PAP TW K+ L S Y ++ K GTL S D G
Sbjct: 876 ASLPCV-ASGVPAPTITWTKETNALT--------SRGPHYNVS-KEGTLLIAQPSAQDAG 925
Query: 211 EYSCEARNSVGY 222
Y C A N+VG+
Sbjct: 926 AYVCTATNTVGF 937
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 10/129 (7%)
Query: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
+RI DAG Y C A +E G E + L V AP + + G L
Sbjct: 633 LRIPAAQERDAGTYTCR--AVNELGDASAE--IQLAVGHAPQLTELPRDVTVELGRSALL 688
Query: 154 RCQDKEGNPAPEYTWFK-DGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
C+ G P P TW + DG L RLG+ S + +G L F +V+ D Y
Sbjct: 689 ACR-ATGRPPPTVTWRRGDGQPL--GLRLGAG--RGSRSRQPDSGVLFFESVAPEDQAPY 743
Query: 213 SCEARNSVG 221
CEARN G
Sbjct: 744 VCEARNVFG 752
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 12/125 (9%)
Query: 97 KNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQ 156
++V D Y CE A + G+ E + + P + S L G V L C
Sbjct: 733 ESVAPEDQAPYVCE--ARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCI 790
Query: 157 DKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEA 216
G P PE W KDG L R ++ G+L + + G YSC A
Sbjct: 791 VLAGRPLPERHWLKDGRPLPPGSRHSIRA----------DGSLHLDRALQEHAGRYSCVA 840
Query: 217 RNSVG 221
N+ G
Sbjct: 841 TNTAG 845
Score = 35.4 bits (80), Expect = 0.061
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 13/129 (10%)
Query: 96 IKNVTRSDAGKYRCEVSAP---SEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVE 152
I + DAG Y C + S Q L +T + + + +A +G V
Sbjct: 916 IAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVT 975
Query: 153 LRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEY 212
L C+ K G+P P TW KD R TN + +G+L+ V D+G Y
Sbjct: 976 LDCEAK-GSPPPLVTWTKDS-------RPVPPITNRYGLL--PSGSLRLAQVQVGDSGHY 1025
Query: 213 SCEARNSVG 221
C A N G
Sbjct: 1026 ECTASNPAG 1034
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 55.5 bits (132), Expect = 6e-08
Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 15/160 (9%)
Query: 87 AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSAL 146
A++ D ++ I + +D G+Y+C S + +V L V AP V
Sbjct: 564 AQLADLSLEISGIIPTDGGRYQCVAS----NANGVTRASVWLLVREAPQVSIHTSSQHFS 619
Query: 147 SGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSK 206
G V++ C G P P +W ++ L E+ R+ + GTL V+
Sbjct: 620 QGVEVKVSCS-ASGYPTPHISWSRESQALQEDSRIHVDAQ----------GTLIIQGVAP 668
Query: 207 LDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVV 246
D G YSC+A N VG + D ++S + A V+V
Sbjct: 669 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 708
Score = 50.1 bits (118), Expect = 2e-06
Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 18/152 (11%)
Query: 70 VSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLE 129
+S+ Q LQ D + + + I+ V DAG Y C+ A +E G +++TVTL
Sbjct: 638 ISWSRESQALQEDSRIHVDA-QGTLIIQGVAPEDAGNYSCQ--ATNEVGT--DQETVTLY 692
Query: 130 VLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSS 189
P+V + G L C+ G P P W++ G+ ++ P GS S
Sbjct: 693 YTDPPSVSAVNAVVLVAVGEEAVLVCE-ASGVPPPRVIWYRGGLEMILAPE-GSSS---- 746
Query: 190 YTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
G L+ + D G Y+C A N +G
Sbjct: 747 -------GKLRIPAAQERDAGTYTCRAVNELG 771
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 55.5 bits (132), Expect = 6e-08
Identities = 62/251 (24%), Positives = 104/251 (41%), Gaps = 31/251 (12%)
Query: 9 LLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEW----- 63
LLLLL+ Y V LG H A +++V +Q + P+K +EW
Sbjct: 5 LLLLLVSYYVGTLGTHTEIKRVA--EEKVTLPCHHQLGL-----PEKDTLD-IEWLLTDN 56
Query: 64 ---KKLGRSVSFVYYQQTLQGDFKNRAEMI------DFNIRIKNVTRSDAGKYRCEVSAP 114
+K+ + S + L + K R D +++I+ + SD G+Y C+V
Sbjct: 57 EGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKVK-- 114
Query: 115 SEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIR 174
G+ + + L+VLV P+ P CE+ G+ + L+C+ G Y W + +
Sbjct: 115 -NSGRYVWSHVI-LKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREK 172
Query: 175 LLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDD 234
E+ RL +S G + ++ +G Y C A N G C R+ V
Sbjct: 173 EGEDERLPPKSRID----YNHPGRVLLQNLTMSYSGLYQCTAGNEAGKESCV-VRVTVQY 227
Query: 235 LNISGIIAAVV 245
+ G++A V
Sbjct: 228 VQSIGMVAGAV 238
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 55.1 bits (131), Expect = 7e-08
Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 25/178 (14%)
Query: 44 QEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSD 103
+ AIL C+ P+ + WKK + D + R + + I N +SD
Sbjct: 164 EPAILECQPPRGHPEPTIYWKK----------DKVRIDDKEERISIRGGKLMISNTRKSD 213
Query: 104 AGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPA 163
AG Y C + + D L V P + L VE RCQ +G+P
Sbjct: 214 AGMYTC---VGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQ-VQGDPQ 269
Query: 164 PEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P W KD L PR G YT+ K T+S D G Y C A N VG
Sbjct: 270 PTVRWKKDDADL---PR-GRYDIKDDYTLRIK------KTMS-TDEGTYMCIAENRVG 316
Score = 50.1 bits (118), Expect = 2e-06
Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 7/131 (5%)
Query: 91 DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150
D+ +RIK +D G Y C +E E + TL V P G
Sbjct: 291 DYTLRIKKTMSTDEGTYMC----IAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRT 346
Query: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTG 210
V C+ K GNP P W K+G + L P Q NS ++ + TG L + + D G
Sbjct: 347 VTFPCETK-GNPQPAVFWQKEGSQNLLFPN-QPQQPNSRCSV-SPTGDLTITNIQRSDAG 403
Query: 211 EYSCEARNSVG 221
Y C+A G
Sbjct: 404 YYICQALTVAG 414
Score = 47.4 bits (111), Expect = 2e-05
Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 32/199 (16%)
Query: 32 PKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID 91
P+DQ V + C+T K + W+K G S + ++ Q Q + +
Sbjct: 336 PRDQIVAQG---RTVTFPCET-KGNPQPAVFWQKEG-SQNLLFPNQPQQPNSRCSVSPTG 390
Query: 92 FNIRIKNVTRSDAGKYRCE---VSAPSEQGQNLEEDTVTLE-----VLVAPAVPSCEVPS 143
++ I N+ RSDAG Y C+ V+ LE V + +L PA + V
Sbjct: 391 -DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG 449
Query: 144 SALSGTVVELRCQDKEGNPAPEYTWFKDGIRLL-ENPRLGSQSTNSSYTMNTKTGTLQFN 202
+AL L+C+ G+P P +W K+G +PR Q + GTLQ
Sbjct: 450 TAL------LKCK-ATGDPLPVISWLKEGFTFPGRDPRATIQ----------EQGTLQIK 492
Query: 203 TVSKLDTGEYSCEARNSVG 221
+ DTG Y+C A +S G
Sbjct: 493 NLRISDTGTYTCVATSSSG 511
Score = 41.6 bits (96), Expect = 9e-04
Identities = 44/182 (24%), Positives = 70/182 (38%), Gaps = 25/182 (13%)
Query: 48 LACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMID----FNIRIKNVTRS- 102
L CK + + +EW K G V +T + D ++ ++ F +RI + RS
Sbjct: 66 LNCKAEGRPTPT-IEWYKDGERV------ETDKDDPRSHRMLLPSGSLFFLRIVHGRRSK 118
Query: 103 -DAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGN 161
D G Y C A + G+ + + L+ +G L CQ G+
Sbjct: 119 PDEGSYVCV--ARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGH 176
Query: 162 PAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG 221
P P W KD +R+ + ++ + G L + K D G Y+C N VG
Sbjct: 177 PEPTIYWKKDKVRI----------DDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVG 226
Query: 222 YR 223
R
Sbjct: 227 ER 228
>gi|190358524 follistatin-like 5 isoform c [Homo sapiens]
Length = 837
Score = 55.1 bits (131), Expect = 7e-08
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 23/194 (11%)
Query: 30 SAPKDQQ--VVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRA 87
S P+DQ+ + A Q A+L+C + T+ + WK+ ++ + + DF +
Sbjct: 247 SLPEDQKLSITAATVGQSAVLSCAI-QGTLRPPIIWKRNNIILNNLDLEDI--NDFGD-- 301
Query: 88 EMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS 147
D ++ I VT + G Y C + Q T +V V P + +
Sbjct: 302 ---DGSLYITKVTTTHVGNYTCYADGYEQVYQ-----THIFQVNVPPVIRVYPESQAREP 353
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G LRC EG P P+ W K+GI + P+L Q T+ + + V
Sbjct: 354 GVTASLRCH-AEGIPKPQLGWLKNGIDI--TPKLSKQ-----LTLQANGSEVHISNVRYE 405
Query: 208 DTGEYSCEARNSVG 221
DTG Y+C A+N G
Sbjct: 406 DTGAYTCIAKNEAG 419
>gi|190358522 follistatin-like 5 isoform b [Homo sapiens]
Length = 846
Score = 55.1 bits (131), Expect = 7e-08
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 23/194 (11%)
Query: 30 SAPKDQQ--VVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRA 87
S P+DQ+ + A Q A+L+C + T+ + WK+ ++ + + DF +
Sbjct: 247 SLPEDQKLSITAATVGQSAVLSCAI-QGTLRPPIIWKRNNIILNNLDLEDI--NDFGD-- 301
Query: 88 EMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS 147
D ++ I VT + G Y C + Q T +V V P + +
Sbjct: 302 ---DGSLYITKVTTTHVGNYTCYADGYEQVYQ-----THIFQVNVPPVIRVYPESQAREP 353
Query: 148 GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKL 207
G LRC EG P P+ W K+GI + P+L Q T+ + + V
Sbjct: 354 GVTASLRCH-AEGIPKPQLGWLKNGIDI--TPKLSKQ-----LTLQANGSEVHISNVRYE 405
Query: 208 DTGEYSCEARNSVG 221
DTG Y+C A+N G
Sbjct: 406 DTGAYTCIAKNEAG 419
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.130 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,597,386
Number of Sequences: 37866
Number of extensions: 448404
Number of successful extensions: 3844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 313
Number of HSP's that attempted gapping in prelim test: 1600
Number of HSP's gapped (non-prelim): 1613
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.