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Search of human proteins with 10835109
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10835109 myotubularin-related protein 3 isoform c [Homo
sapiens]
(1198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 2464 0.0
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 2370 0.0
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 2362 0.0
gi|217272865 myotubularin related protein 4 [Homo sapiens] 1094 0.0
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 350 5e-96
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 350 5e-96
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 350 5e-96
gi|4557896 myotubularin [Homo sapiens] 335 2e-91
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 317 6e-86
gi|21361759 myotubularin related protein 8 [Homo sapiens] 282 1e-75
gi|225543474 myotubularin related protein 7 [Homo sapiens] 281 3e-75
gi|134142348 myotubularin related protein 6 [Homo sapiens] 280 8e-75
gi|19923424 myotubularin related protein 9 [Homo sapiens] 240 5e-63
gi|239735519 SET binding factor 1 [Homo sapiens] 176 2e-43
gi|29788755 SET binding factor 2 [Homo sapiens] 172 1e-42
gi|124028527 myotubularin related protein 10 [Homo sapiens] 133 9e-31
gi|94721263 myotubularin related protein 12 [Homo sapiens] 108 3e-23
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 102 3e-21
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 102 3e-21
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 83 1e-15
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 83 1e-15
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 83 1e-15
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 80 9e-15
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 79 3e-14
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 72 2e-12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 68 5e-11
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 68 6e-11
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 67 8e-11
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 67 8e-11
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 65 3e-10
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 2464 bits (6385), Expect = 0.0
Identities = 1198/1198 (100%), Positives = 1198/1198 (100%)
Query: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL
Sbjct: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
Query: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP
Sbjct: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
Query: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN
Sbjct: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
Query: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV
Sbjct: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
Query: 241 SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS 300
SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS
Sbjct: 241 SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS 300
Query: 301 GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ 360
GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ
Sbjct: 301 GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ 360
Query: 361 SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT 420
SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT
Sbjct: 361 SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT 420
Query: 421 PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL 480
PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL
Sbjct: 421 PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL 480
Query: 481 DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540
DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL
Sbjct: 481 DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540
Query: 541 RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP 600
RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP
Sbjct: 541 RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP 600
Query: 601 DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP 660
DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP
Sbjct: 601 DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP 660
Query: 661 LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED 720
LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED
Sbjct: 661 LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED 720
Query: 721 PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ 780
PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ
Sbjct: 721 PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ 780
Query: 781 VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP 840
VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP
Sbjct: 781 VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP 840
Query: 841 NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH 900
NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH
Sbjct: 841 NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH 900
Query: 901 RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN 960
RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN
Sbjct: 901 RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN 960
Query: 961 GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM 1020
GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM
Sbjct: 961 GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM 1020
Query: 1021 SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPD 1080
SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPD
Sbjct: 1021 SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPD 1080
Query: 1081 SESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHH 1140
SESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHH
Sbjct: 1081 SESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHH 1140
Query: 1141 CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN 1198
CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN
Sbjct: 1141 CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN 1198
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 2370 bits (6142), Expect = 0.0
Identities = 1161/1198 (96%), Positives = 1161/1198 (96%), Gaps = 37/1198 (3%)
Query: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL
Sbjct: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
Query: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP
Sbjct: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
Query: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN
Sbjct: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
Query: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV
Sbjct: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
Query: 241 SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS 300
SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS
Sbjct: 241 SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS 300
Query: 301 GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ 360
GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ
Sbjct: 301 GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ 360
Query: 361 SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT 420
SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT
Sbjct: 361 SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT 420
Query: 421 PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL 480
PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL
Sbjct: 421 PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL 480
Query: 481 DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540
DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL
Sbjct: 481 DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540
Query: 541 RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP 600
RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP
Sbjct: 541 RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP 600
Query: 601 DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP 660
DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP
Sbjct: 601 DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP 660
Query: 661 LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED 720
LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED
Sbjct: 661 LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED 720
Query: 721 PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ 780
PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ
Sbjct: 721 PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ 780
Query: 781 VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP 840
VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP
Sbjct: 781 VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP 840
Query: 841 NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH 900
NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH
Sbjct: 841 NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH 900
Query: 901 RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN 960
RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN
Sbjct: 901 RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN 960
Query: 961 GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM 1020
GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM
Sbjct: 961 GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM 1020
Query: 1021 SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPD 1080
SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEV
Sbjct: 1021 SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEV----- 1075
Query: 1081 SESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHH 1140
MTRWLPDHLAAHCYACDSAFWLASRKHH
Sbjct: 1076 --------------------------------MTRWLPDHLAAHCYACDSAFWLASRKHH 1103
Query: 1141 CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN 1198
CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN
Sbjct: 1104 CRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN 1161
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 2362 bits (6122), Expect = 0.0
Identities = 1161/1207 (96%), Positives = 1161/1207 (96%), Gaps = 46/1207 (3%)
Query: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL
Sbjct: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
Query: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP
Sbjct: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
Query: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN
Sbjct: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
Query: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV
Sbjct: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
Query: 241 SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS 300
SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS
Sbjct: 241 SWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNAS 300
Query: 301 GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ 360
GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ
Sbjct: 301 GAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQ 360
Query: 361 SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT 420
SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT
Sbjct: 361 SLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRT 420
Query: 421 PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL 480
PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL
Sbjct: 421 PQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWL 480
Query: 481 DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540
DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL
Sbjct: 481 DCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540
Query: 541 RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP 600
RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP
Sbjct: 541 RAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSP 600
Query: 601 DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP 660
DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP
Sbjct: 601 DDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDP 660
Query: 661 LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED 720
LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED
Sbjct: 661 LSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKED 720
Query: 721 PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ 780
PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ
Sbjct: 721 PLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQ 780
Query: 781 VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP 840
VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP
Sbjct: 781 VPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGP 840
Query: 841 NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH 900
NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH
Sbjct: 841 NVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVH 900
Query: 901 RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN 960
RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN
Sbjct: 901 RTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCAN 960
Query: 961 GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM 1020
GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM
Sbjct: 961 GEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGM 1020
Query: 1021 SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPD 1080
SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEV
Sbjct: 1021 SVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEV----- 1075
Query: 1081 SESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHH 1140
MTRWLPDHLAAHCYACDSAFWLASRKHH
Sbjct: 1076 --------------------------------MTRWLPDHLAAHCYACDSAFWLASRKHH 1103
Query: 1141 CR---------NCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDK 1191
CR NCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDK
Sbjct: 1104 CRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDK 1163
Query: 1192 PIAATSN 1198
PIAATSN
Sbjct: 1164 PIAATSN 1170
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 1094 bits (2830), Expect = 0.0
Identities = 611/1240 (49%), Positives = 793/1240 (63%), Gaps = 87/1240 (7%)
Query: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
M EE SLE IQA +FP K+L++E+ENLQVPF L GE EF+GRA DA+IA+SNYRL
Sbjct: 1 MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL 60
Query: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
HIKFK+S++NVPL++I+SVE RD+FQLH++CKD KV+RC FSTF+QCQEWL RL+ A
Sbjct: 61 HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR 120
Query: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
PAK EDLF+FAYHAWC+ + +E++QH LC+PGEH+ R + E+ RMGFD+ N WR+S+
Sbjct: 121 PAKPEDLFAFAYHAWCLGL--TEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSH 178
Query: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
IN YKLC SYPQ+L+VP WITDKELE+V+SFRSWKRIP V+YRH NGA IARC QPE+
Sbjct: 179 INSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEI 238
Query: 241 SWWGWRNADDEHLVQSVAKACASD--SRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSN 298
SWWGWRNADDE+LV S+AKACA D +R++G LST N + D +FDSSL+
Sbjct: 239 SWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTS-----EACDADFDSSLTA 293
Query: 299 ASGAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRS 358
SG ES A PQKLLILDARSY AAVANRAKGGGCEC EYYPNCEVVFMGMANIH+IR S
Sbjct: 294 CSGVESTAA-PQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNS 352
Query: 359 FQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWD 418
FQ LR +C+QMPDP NWLSALESTKWL HLSV+LK+A+LV + VD++ RPVLVHCSDGWD
Sbjct: 353 FQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWD 412
Query: 419 RTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQ 478
RTPQIVALAK+LLDPYYRT+EGFQVLVE +WLDFGHKF DRCGH EN +D NE+CPVFLQ
Sbjct: 413 RTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQ 472
Query: 479 WLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWS 538
WLD VHQL +QFPC FEFNEAFLVKLVQHTYSCL+GTFL NN ER +++ +RTCSVW+
Sbjct: 473 WLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWA 532
Query: 539 LLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGT 598
LLRAGNK F N LY+ S+ VL+PVCHVR L LW+AVYLP SP T +++ Y +P
Sbjct: 533 LLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVA 592
Query: 599 SPDD---PPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAG 655
+ L RLPKTRS D+L +ACD + PL +R SDP+LN QE R LE
Sbjct: 593 QSQEFSGRSLDRLPKTRSMDDLLSACDTSSPL-TRTSSDPNLNNHCQEVRVGLEPWHSNP 651
Query: 656 PGEDPLSADS-LGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHR----- 709
G + DS +G P + G E+ + + Q + + + K P+++
Sbjct: 652 EGSETSFVDSGVGGPQQTVG--EVGLPPPLPSSQKDYLSNKPFKSHKSC-SPSYKLLNTA 708
Query: 710 AGIEIQEGKEDPLLE--KESRRKTPEASA---IGLHQDPELGDAALRSHLDMSWPLFSQG 764
E++ DP ++ +E++ P+ SA +G D +G+ + S+
Sbjct: 709 VPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLD-GIGEPPEHCPETEAVSALSKV 767
Query: 765 ISEQQSGLSVLLSSLQVPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQ 824
IS + G+ S Q P G + + +++L +P + + S
Sbjct: 768 ISNKCDGVCNFPESSQNSPTGTPQ--------------QAQPDSMLGVPSKCVLDHSLST 813
Query: 825 SCSLLPSQVPFETRGPNVDSSTDMLVED---KVKSVSGPQ--------GHHRSCLVNSGK 873
C+ P +T +D STD L +D V S+S + H + G
Sbjct: 814 VCN--PPSAACQT---PLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGN 868
Query: 874 DRLPQTMEP---SPSETSLVERPQVGSVVHRTS-LGSTL-SLTRSPCALPLAEC-KEGLV 927
+R Q +E LV +P S + S LGS S + P E L+
Sbjct: 869 NRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLL 928
Query: 928 CNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSAHLHS- 986
G S++P ++ QM T G C G+ + + S S S S+ H
Sbjct: 929 SYGC------CSKRP---NSKQMRAT--GPCFGGQWAQREGVKSPVCS--SHSNGHCTGP 975
Query: 987 RNLHHKWLHSH-----SGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQE 1041
+ WL SH S +P + P +LDDDG+ TD IQ RLRQIE+G++QE
Sbjct: 976 GGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQE 1035
Query: 1042 VETLKKQVQELKSRLESQYLTS-SLHFNGDFGDEVTSIPDSESNLDQNCLSRCSTEIFSE 1100
VE L++QV+EL+ RL+ ++ + D+ D+ T + +S+ + ++ S S + SE
Sbjct: 1036 VEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSE 1095
Query: 1101 ASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVP 1160
ASWE VDK++TE+TRW+PDH+A+HCY CD FWLA R+HHCRNCGNVFC+ CC+ K+P+P
Sbjct: 1096 ASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIP 1155
Query: 1161 SQQLFEPSRVCKSCYSSLHPTSSS--IDLELDKPIAATSN 1198
QQL++P VC SCY + + + + +L KPIA S+
Sbjct: 1156 DQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS 1195
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 350 bits (898), Expect = 5e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 105 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 164
Query: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 165 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 210
Query: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 211 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 261
Query: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 262 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 308
Query: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 309 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 336
Query: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 337 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 396
Query: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 397 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 456
Query: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 457 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 516
Query: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 517 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 576
Query: 573 SAVYL---PCPSPTTPV 586
Y+ P P P+
Sbjct: 577 VGYYIRWNPRMKPQEPI 593
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 350 bits (898), Expect = 5e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 33 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 92
Query: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 93 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 138
Query: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 139 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 189
Query: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 190 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 236
Query: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 237 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 264
Query: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 265 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 324
Query: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 325 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 384
Query: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 385 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 444
Query: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 445 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 504
Query: 573 SAVYL---PCPSPTTPV 586
Y+ P P P+
Sbjct: 505 VGYYIRWNPRMKPQEPI 521
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 350 bits (898), Expect = 5e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 33 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 92
Query: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 93 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 138
Query: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 139 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 189
Query: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 190 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 236
Query: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 237 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 264
Query: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 265 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 324
Query: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 325 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 384
Query: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 385 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 444
Query: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 445 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 504
Query: 573 SAVYL---PCPSPTTPV 586
Y+ P P P+
Sbjct: 505 VGYYIRWNPRMKPQEPI 521
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 335 bits (858), Expect = 2e-91
Identities = 197/538 (36%), Positives = 294/538 (54%), Gaps = 74/538 (13%)
Query: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIRCQ 100
+ ++NYRL+++ E+ +++VPL +I +E + + L +TCKD + +R
Sbjct: 63 VYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKDMRNLRFA 122
Query: 101 FSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAY-HAWCMEVYASEKEQHGDLCRPGEHVTS 159
LK+ ++ R +I ++F H+ + + +E++ + D G V +
Sbjct: 123 ----------LKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFNVD----GWTVYN 168
Query: 160 RFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIP 219
+ E R G N+ WRI+ IN+ Y+LC +YP L+VP +D +L V++FRS RIP
Sbjct: 169 PVE-EYRRQGLP-NHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIP 226
Query: 220 AVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSR 279
+ + H N VI RC QP V G RN DDE + + R T++
Sbjct: 227 VLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVI-----------------RETNK 269
Query: 280 DFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYY 339
Q KL I DAR AVAN+A GGG E + Y
Sbjct: 270 ----------------------------QISKLTIYDARPSVNAVANKATGGGYESDDAY 301
Query: 340 PNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVV 399
N E+ F+ + NIH +R S + ++ + + +WLS+LEST WL H+ ++L A+ V
Sbjct: 302 HNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVA 361
Query: 400 HAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADR 459
V + VLVHCSDGWDRT Q+ +LA L+LD +YR+IEGF++LV+ EW+ FGHKFA R
Sbjct: 362 DKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASR 421
Query: 460 CGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCN 519
GHG+ + +R P+FLQ++DCV Q+ +QFP +FEFNE FL+ ++ H YSC FGTFL N
Sbjct: 422 IGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFN 481
Query: 520 NAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYL 577
R + ERT S+WSL+ + + FKN Y+ + VLYPV +R+L LW Y+
Sbjct: 482 CESARERQKVTERTVSLWSLINSNKEKFKNPFYTKEINRVLYPVASMRHLELWVNYYI 539
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 317 bits (811), Expect = 6e-86
Identities = 189/564 (33%), Positives = 290/564 (51%), Gaps = 89/564 (15%)
Query: 44 FVGRAEDAIIALSNYRLHIKFKES----LVNVPLQLIESVEC-------RDIFQLHLTCK 92
F+G A + +++++L+ K E +++VPL +I VE + + + CK
Sbjct: 119 FMG-AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCK 177
Query: 93 DCKVIRCQFSTFEQCQEWL-KRLNNAIRPPAKIEDLFSFAY------HAWCMEVYASEKE 145
D + +R + EQ + + + LN P + + LF+F+Y + W +VY
Sbjct: 178 DMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGW--KVYDPV-- 233
Query: 146 QHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKE 205
+E +R G N +W+IS IN Y+ C +YP ++VP + D +
Sbjct: 234 -----------------SEYKRQGLP-NESWKISKINSNYEFCDTYPAIIVVPTSVKDDD 275
Query: 206 LESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDS 265
L V++FR+ R+P + + H + A I RC QP V R +DE +Q++ A A
Sbjct: 276 LSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANA--- 332
Query: 266 RSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVA 325
Q KL+I DAR + A
Sbjct: 333 ------------------------------------------QSHKLIIFDARQNSVADT 350
Query: 326 NRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWL 385
N+ KGGG E YPN E+VF+ + NIH +R S + L+ + D WLS ++ T WL
Sbjct: 351 NKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWL 410
Query: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
++ +LL A+ + ++ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI+GF+ LV
Sbjct: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
Query: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
E EW+ FGH+FA R GHG ++ +R P+FLQ++DCV Q+ RQFP +FEFNE FL+ ++
Sbjct: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
Query: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCH 565
H YSCLFGTFLCN ++R ++ +T S+WS + + F N + + VLYPV
Sbjct: 531 DHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVAS 590
Query: 566 VRNLMLWSAVYL---PCPSPTTPV 586
+ +L LW Y+ P P P+
Sbjct: 591 LSHLELWVNYYVRWNPRMRPQMPI 614
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 282 bits (722), Expect = 1e-75
Identities = 171/492 (34%), Positives = 250/492 (50%), Gaps = 63/492 (12%)
Query: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
L L CK+ +V + C E L + PA EDL++F+Y+ S KE
Sbjct: 70 LTLRCKNFRVAHFVLDSDLVCHEVYISLLK-LSQPALPEDLYAFSYNP------KSSKEM 122
Query: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
+ + ++ + RMG N W I++ N Y++C +YP E++VP +T +
Sbjct: 123 RESGWKLIDPIS-----DFGRMGIPNRN-WTITDANRNYEICSTYPPEIVVPKSVTLGTV 176
Query: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
S FRS +R+P + Y ++ N A I RC QP +S + R DDE L++++++
Sbjct: 177 VGSSKFRSKERVPVLSYLYKENNAAICRCSQP-LSGFYTRCVDDELLLEAISQT------ 229
Query: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
N G Q + ++D R A+AN
Sbjct: 230 ----------------NPGS-----------------------QFMYVVDTRPKLNAMAN 250
Query: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385
RA G G E + Y N FMG+ NIH +R S Q L +C + P +LS LES+ WL
Sbjct: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWL 310
Query: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
H+ ++ + + + AV ++ VLVHCSDGWDRT Q+ ++A +LLDP+YRT +G +L+
Sbjct: 311 RHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILI 370
Query: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
E EW+ GHKF+ RCGH + D E P+F Q+LDC+ QL QFPC+FEFNE FL+++
Sbjct: 371 EKEWISMGHKFSQRCGHLDG--DSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIH 428
Query: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSS-QSEAVLYPVC 564
H +SC FG FL N K+R + E+T SVW L F+N LY VL P
Sbjct: 429 DHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPST 488
Query: 565 HVRNLMLWSAVY 576
N+ W +Y
Sbjct: 489 VPYNIQFWCGMY 500
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 281 bits (718), Expect = 3e-75
Identities = 174/496 (35%), Positives = 255/496 (51%), Gaps = 67/496 (13%)
Query: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
L + CK+ ++I+ C + L RP K E+L+ F+++ + E+EQ
Sbjct: 70 LLIRCKNFQIIQLIIPQERDCHDVYISLIRLARP-VKYEELYCFSFNPMLDK---EEREQ 125
Query: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
L E T RMG N+ W++S++N Y++C SYP EL VP T +
Sbjct: 126 GWVLIDLSEEYT--------RMGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHII 176
Query: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
S FRS +R P + Y ++ N A I R QP +S + R +DE ++Q++ KA
Sbjct: 177 VGSSKFRSRRRFPVLSYYYKDNHASICRSSQP-LSGFSARCLEDEQMLQAIRKA------ 229
Query: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
N DF + ++D R A+AN
Sbjct: 230 ---------NPGSDF------------------------------VYVVDTRPKLNAMAN 250
Query: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385
RA G G E + Y N + F+G+ NIH +R S Q + +C + P ++L LE++ WL
Sbjct: 251 RAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWL 310
Query: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
H+ ++ + + + AV ++ VLVHCSDGWDRT Q+ ++A LLLDP+YRT++GF VL+
Sbjct: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
Query: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
E +W+ FGHKF R +G D E PV Q+++CV QL QFPC+FEFNE FL+ +
Sbjct: 371 EKDWISFGHKFNHR--YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
Query: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLY---SSQSEAVLYP 562
H YSC FG FLCN+ KER E QERT S+W+ L + N L+ SQ++ L+
Sbjct: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
Query: 563 VCHVRNLM--LWSAVY 576
N M WS +Y
Sbjct: 489 PTTPCNFMYKFWSGMY 504
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 280 bits (715), Expect = 8e-75
Identities = 176/493 (35%), Positives = 253/493 (51%), Gaps = 64/493 (12%)
Query: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
L + CK+ + + C + L + AK EDL++F+Y+ + SE+ Q
Sbjct: 68 LVIQCKNFRTVHFIVPRERDCHDIYNSLLQ-LSKQAKYEDLYAFSYNP---KQNDSERLQ 123
Query: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
L E E +RMG N+ W++S+ N YK+C +YP+EL VP + +
Sbjct: 124 GWQLIDLAE--------EYKRMGVP-NSHWQLSDANRDYKICETYPRELYVPRIASKPII 174
Query: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
S FRS R P + Y HQ A I RC QP +S + R +DEHL+Q+++KA +
Sbjct: 175 VGSSKFRSKGRFPVLSYYHQDKEAAICRCSQP-LSGFSARCLEDEHLLQAISKANPVN-- 231
Query: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
+ + ++D R A+AN
Sbjct: 232 -------------------------------------------RYMYVMDTRPKLNAMAN 248
Query: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSL-RLLCTQMPDPGNWLSALESTKWL 385
RA G G E + Y N F+G+ NIH +R S Q L + T+ ++ S LES+ WL
Sbjct: 249 RAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWL 308
Query: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
H+ ++ +A+ + A+ + VLVHCSDGWDRT Q+ +L LLLD YYRTI+GF VL+
Sbjct: 309 RHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLI 368
Query: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
E +W+ FGHKF++RC G+ D E PVF Q+L+CV L QFP +FEF+EAFL+++
Sbjct: 369 EKDWISFGHKFSERC--GQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIH 426
Query: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSE--AVLYPV 563
+H +SC FG FL N KER E +E+T S+W L K + N LYSS+S VL P
Sbjct: 427 EHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPN 486
Query: 564 CHVRNLMLWSAVY 576
N W +Y
Sbjct: 487 TVSFNFKFWRNMY 499
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 240 bits (613), Expect = 5e-63
Identities = 151/493 (30%), Positives = 233/493 (47%), Gaps = 68/493 (13%)
Query: 89 LTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHG 148
+ CKD ++I+ E+C + A+ I ++ F Y
Sbjct: 71 IKCKDFRIIQLDIPGMEECLNIASSIE-ALSTLDSITLMYPFFYRPMF------------ 117
Query: 149 DLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELES 208
++ G H S + + + WR+S +N+++ +C SYP + VP I D+ L
Sbjct: 118 EVIEDGWH--SFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRK 175
Query: 209 VSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSS 268
V++FR R P + Y H+ NG VI R GQP G R +DE L+ + +A
Sbjct: 176 VATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRA-------- 227
Query: 269 GSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRA 328
++ I+D RS A RA
Sbjct: 228 ----------------------------------------GKRGYIIDTRSLNVAQQTRA 247
Query: 329 KGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWLHH 387
KGGG E +YP + + H ++ S L C Q + WLS LE++ WL H
Sbjct: 248 KGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLSKLEASNWLTH 307
Query: 388 LSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEM 447
+ +L +A L +D++ +L+H ++G D T Q+ +LA+++L+P RTI GF+ L+E
Sbjct: 308 IKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIER 367
Query: 448 EWLDFGHKFADRCGHGENSDDLNE-RCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQ 506
EWL GH F RC + + PVFL +LDCV Q+ RQFPCSFEFNE FL+ L +
Sbjct: 368 EWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFE 427
Query: 507 HTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNK--AFKNLLYSSQSEAVLYPVC 564
H Y+ FGTFL NN ER + Q++T S+WS + ++ F N L+ + + V++P
Sbjct: 428 HAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEA-NNLVIWPSV 486
Query: 565 HVRNLMLWSAVYL 577
++L LW ++L
Sbjct: 487 APQSLPLWEGIFL 499
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 176 bits (445), Expect = 2e-43
Identities = 144/475 (30%), Positives = 220/475 (46%), Gaps = 84/475 (17%)
Query: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
+RIS +N Y +C SYP LIVP + D L+ VS R P V +R + AV+ R
Sbjct: 1150 FRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRS 1209
Query: 236 ----GQPEVSWWGWRNA-------------DDEHLVQSVAKACASDSRSSG--------- 269
G+ V + +NA + E +Q+V + + +SG
Sbjct: 1210 GGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSS 1269
Query: 270 ------------------SKLSTRNTSRDFPNG--GDLSDVEFDSSL-----SNASGAES 304
+ ++ + R P G G + S L S +G ++
Sbjct: 1270 AHMGSHVPSPRARVTTLSNPMAASASRRTAPRGKWGSVRTSGRSSGLGTDVGSRLAGRDA 1329
Query: 305 LAIQ------PQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRS 358
LA P + R+ + ++A+ G + E+V + + ++ S
Sbjct: 1330 LAPPQANGGPPDPGFLRPQRAALYILGDKAQLKGVRS-DPLQQWELVPIEVFEARQVKAS 1388
Query: 359 FQSLRLLCTQ-----MPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHC 413
F+ L C P P ++L +LE ++WL + LL+ ++LVV +D VLV
Sbjct: 1389 FKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSS-VLVGL 1447
Query: 414 SDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGH---GENSDDLN 470
DGWD T Q+V+L +LL DP+YRT+EGF++LVE EWL FGH+F+ R H G++S
Sbjct: 1448 EDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSG--- 1504
Query: 471 ERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNN---------- 520
PVFLQ+LDCVHQ+ QFP FEF++ +L L H S F TFL ++
Sbjct: 1505 -FTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLL 1563
Query: 521 AKERGEKHTQERTCSVWSLLRAGNK---AFKNLLYSSQSEAVLYPVCHVRNLMLW 572
+E+GE+ Q SVW + +K F N +Y+ + VL P +V NL +W
Sbjct: 1564 YEEKGERRGQVPCRSVWEYVDRLSKRTPVFHNYMYAPEDAEVLRPYSNVSNLKVW 1618
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 172 bits (437), Expect = 1e-42
Identities = 136/455 (29%), Positives = 208/455 (45%), Gaps = 70/455 (15%)
Query: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
+RI+ N Y LC SYP L+VP + D L V+ R+P V +++ +G ++ R
Sbjct: 1138 FRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRS 1197
Query: 236 G-------------------QPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKLST-- 274
G P S + + E +Q++ A + + G+ T
Sbjct: 1198 GGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVR 1257
Query: 275 -------------RNTSRDFPN-------GGDLSDVEFDSSLSNASGAESLAIQPQKLLI 314
R+++R + G L+ + +S SN+S ++ ++ Q L
Sbjct: 1258 PAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAALY 1317
Query: 315 LDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGN 374
+ + + N E+ NCE V + I ++ SF+ L C P +
Sbjct: 1318 IFGEK--SQLRNFKV-------EFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTD 1368
Query: 375 ----WLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLL 430
+L AL ++W L +++ A+ VV V ++ VLV +GWD T Q+ +L +LL
Sbjct: 1369 SEVTFLKALGDSEWFPQLHRIMQLAV-VVSEVLENGSSVLVCLEEGWDITAQVTSLVQLL 1427
Query: 431 LDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQF 490
DP+YRT+EGFQ+LVE EWL FGHKF+ R N + PVFLQ+LDCVHQ+ Q+
Sbjct: 1428 SDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQG-SGFAPVFLQFLDCVHQVHNQY 1486
Query: 491 PCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKER----------GEKHTQERTCSVWSLL 540
P FEFN +L L H S F TFL ++ ER GEKH ++ C +W +
Sbjct: 1487 PTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVC-IWECI 1545
Query: 541 RAGNK---AFKNLLYSSQSEAVLYPVCHVRNLMLW 572
+K F N LYS L P +V +L W
Sbjct: 1546 DRMHKRSPIFFNYLYSPLEIEALKPNVNVSSLKKW 1580
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 133 bits (335), Expect = 9e-31
Identities = 67/185 (36%), Positives = 111/185 (60%), Gaps = 6/185 (3%)
Query: 349 MANIHSIRRSFQSLRLLCTQMP---DPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQD 405
+ NI ++ +F L+ LC P WLS+LE+T+WL ++ LK + +V+ ++
Sbjct: 336 LPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESK 395
Query: 406 QRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGEN 465
V++ +G D + + +L +++LDPY+RTI GFQ L++ EW+ G++F DRC H +
Sbjct: 396 HLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKR 455
Query: 466 SDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERG 525
S+ + P+FL +LD QL Q+P +FEF+E +L L T LFGTFL N+ +R
Sbjct: 456 SE---KESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRV 512
Query: 526 EKHTQ 530
++ T+
Sbjct: 513 KQSTE 517
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 108 bits (270), Expect = 3e-23
Identities = 65/182 (35%), Positives = 95/182 (52%), Gaps = 5/182 (2%)
Query: 346 FMGMANIHSIRRSFQSLRLL--CTQMPDPG-NWLSALESTKWLHHLSVLLKSALLVVHAV 402
F+ + I + F+ L L+ T+ D W S LES+ WL + LK A+ + +
Sbjct: 321 FLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECM 380
Query: 403 DQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGH 462
+ VL+ + D I +L +L++DP+ RT GFQ L++ EW+ GH F DRC H
Sbjct: 381 EAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNH 440
Query: 463 GENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAK 522
+D E PVFL +LDCV QL Q P +FEF E +L L Y +F TF N+
Sbjct: 441 LRQND--KEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPH 498
Query: 523 ER 524
++
Sbjct: 499 QK 500
Score = 32.7 bits (73), Expect = 2.1
Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 22/131 (16%)
Query: 86 QLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAI----RPPAKIEDLFSFAYHAWCMEVYA 141
+L + CKD +V QF +E +KR+ + I + P ++ LF F+Y
Sbjct: 138 KLIIHCKDLRVF--QFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSY--------- 186
Query: 142 SEKEQHGDLCRPGEHVT--SRFKN---EVERMGFDMNNAWRISNINEKYKLCGSYPQELI 196
+ Q+ + P H K+ E+ER +M ++ ++NE YK+C P +
Sbjct: 187 ATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMK--YKAVSVNEGYKVCERLPAYFV 244
Query: 197 VPAWITDKELE 207
VP + ++ ++
Sbjct: 245 VPTPLPEENVQ 255
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 102 bits (253), Expect = 3e-21
Identities = 91/270 (33%), Positives = 123/270 (45%), Gaps = 30/270 (11%)
Query: 349 MANIHSIRRSFQSLRLLCTQMPDPG----NWLSALESTKWLHHLSVLLKSALLVVHAVDQ 404
+ ++ ++ + LR LC +PD WLSALE T+WL ++ L+ A + V
Sbjct: 309 LPSLADVQLAHLRLRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTS 366
Query: 405 DQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGE 464
R V++ D + +L +LL P RT+ GFQ LV+ EW+ GH F R G
Sbjct: 367 RVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG--- 423
Query: 465 NSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKER 524
+E PVFL +LDCV QL +QFP FEF+E FL+ L TFL N ER
Sbjct: 424 -GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 482
Query: 525 GEK------HTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLP 578
G++ +TQ T +S AGN NL S + Y + L + Y P
Sbjct: 483 GKQSGQLNSYTQVYTPG-YSQPPAGNSF--NLQLSVWDWDLRYSNAQI--LQFQNPGYDP 537
Query: 579 --CPSPTTPVDDSCAPYPAPGTSPDDPPLS 606
CP DS P P P PP S
Sbjct: 538 EHCP-------DSWLPRPQPSFMVPGPPSS 560
Score = 36.6 bits (83), Expect = 0.15
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
WR+S +NE++ + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 214 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLLRC 272
Query: 236 G 236
G
Sbjct: 273 G 273
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 102 bits (253), Expect = 3e-21
Identities = 91/270 (33%), Positives = 123/270 (45%), Gaps = 30/270 (11%)
Query: 349 MANIHSIRRSFQSLRLLCTQMPDPG----NWLSALESTKWLHHLSVLLKSALLVVHAVDQ 404
+ ++ ++ + LR LC +PD WLSALE T+WL ++ L+ A + V
Sbjct: 237 LPSLADVQLAHLRLRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTS 294
Query: 405 DQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGE 464
R V++ D + +L +LL P RT+ GFQ LV+ EW+ GH F R G
Sbjct: 295 RVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG--- 351
Query: 465 NSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKER 524
+E PVFL +LDCV QL +QFP FEF+E FL+ L TFL N ER
Sbjct: 352 -GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
Query: 525 GEK------HTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLP 578
G++ +TQ T +S AGN NL S + Y + L + Y P
Sbjct: 411 GKQSGQLNSYTQVYTPG-YSQPPAGNSF--NLQLSVWDWDLRYSNAQI--LQFQNPGYDP 465
Query: 579 --CPSPTTPVDDSCAPYPAPGTSPDDPPLS 606
CP DS P P P PP S
Sbjct: 466 EHCP-------DSWLPRPQPSFMVPGPPSS 488
Score = 36.6 bits (83), Expect = 0.15
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
WR+S +NE++ + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLLRC 200
Query: 236 G 236
G
Sbjct: 201 G 201
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sapiens]
Length = 600
Score = 83.2 bits (204), Expect = 1e-15
Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 27/216 (12%)
Query: 987 RNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIE---SGHQQEVE 1043
+ + + HS R A RSH + +Q +L Q+ S ++E++
Sbjct: 391 KQMEERLQHSERARQGAEE------RSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELK 444
Query: 1044 TLKKQVQELKSRLESQYLTSSL------HFNGDFGDEVTSIPDSESNLDQNC--LSRCST 1095
+ K+Q Q L+ L+ + TSSL G E+ + D ++ L + C +
Sbjct: 445 SEKEQRQALQRELQHEKDTSSLLRMELQQVEG-LKKELRELQDEKAELQKICEEQEQALQ 503
Query: 1096 EIFSEASWEQVDKQDTEMTR-------WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVF 1148
E+ S ++ +D + WL D A HC C+ F ++ RKHHCRNCG++F
Sbjct: 504 EMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIF 563
Query: 1149 CSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSS 1184
C++C + ++ +PS +P RVC SC++ L SS
Sbjct: 564 CNTCSSNELALPSYP--KPVRVCDSCHTLLLQRCSS 597
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sapiens]
Length = 600
Score = 83.2 bits (204), Expect = 1e-15
Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 27/216 (12%)
Query: 987 RNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIE---SGHQQEVE 1043
+ + + HS R A RSH + +Q +L Q+ S ++E++
Sbjct: 391 KQMEERLQHSERARQGAEE------RSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELK 444
Query: 1044 TLKKQVQELKSRLESQYLTSSL------HFNGDFGDEVTSIPDSESNLDQNC--LSRCST 1095
+ K+Q Q L+ L+ + TSSL G E+ + D ++ L + C +
Sbjct: 445 SEKEQRQALQRELQHEKDTSSLLRMELQQVEG-LKKELRELQDEKAELQKICEEQEQALQ 503
Query: 1096 EIFSEASWEQVDKQDTEMTR-------WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVF 1148
E+ S ++ +D + WL D A HC C+ F ++ RKHHCRNCG++F
Sbjct: 504 EMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIF 563
Query: 1149 CSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSS 1184
C++C + ++ +PS +P RVC SC++ L SS
Sbjct: 564 CNTCSSNELALPSYP--KPVRVCDSCHTLLLQRCSS 597
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sapiens]
Length = 708
Score = 83.2 bits (204), Expect = 1e-15
Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 27/216 (12%)
Query: 987 RNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIE---SGHQQEVE 1043
+ + + HS R A RSH + +Q +L Q+ S ++E++
Sbjct: 499 KQMEERLQHSERARQGAEE------RSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELK 552
Query: 1044 TLKKQVQELKSRLESQYLTSSL------HFNGDFGDEVTSIPDSESNLDQNC--LSRCST 1095
+ K+Q Q L+ L+ + TSSL G E+ + D ++ L + C +
Sbjct: 553 SEKEQRQALQRELQHEKDTSSLLRMELQQVEG-LKKELRELQDEKAELQKICEEQEQALQ 611
Query: 1096 EIFSEASWEQVDKQDTEMTR-------WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVF 1148
E+ S ++ +D + WL D A HC C+ F ++ RKHHCRNCG++F
Sbjct: 612 EMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIF 671
Query: 1149 CSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSS 1184
C++C + ++ +PS +P RVC SC++ L SS
Sbjct: 672 CNTCSSNELALPSYP--KPVRVCDSCHTLLLQRCSS 705
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 80.5 bits (197), Expect = 9e-15
Identities = 116/497 (23%), Positives = 184/497 (37%), Gaps = 71/497 (14%)
Query: 696 ATKEESGVEEPAHRAGIEIQEGKEDPLLEKESRRKTPEASAIGLHQDPELGDAAL----- 750
A +E G P AGI + P EKE A G G ++
Sbjct: 431 ADPQEKGQGGPGGAAGISL------PASEKEEDLSNNNLEAEGTDGASLAGTSSCSCLDS 484
Query: 751 RSHLDMSWPL------FSQGISEQQSGLSVLLSSLQVPPRGEDSLE--VPVEQFRIEEIA 802
R HLD W + ++ I+ + G+ L +++ P+ SL+ V ++ E +A
Sbjct: 485 RLHLD-GWEVGADDAETAEMIAHRTGGMK-LSATVIFNPKSPTSLDSAVATQEAASEPVA 542
Query: 803 EGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGPNVDSSTDMLVEDKVK-SVSGPQ 861
EG + + T + LL S V + G DS D++ + K S G
Sbjct: 543 EGMDGGPHKL--------STGATNCLLHSCVCCGSCG---DSREDVVERLREKCSPGGVI 591
Query: 862 GHHRSCLVNSGKDRLPQTME--PSPSETSLVERPQVGSVVHRTSLGSTLSLTRSPCALPL 919
G + + DR P+ E P PSE + S G S LP
Sbjct: 592 GASYAAGLAKASDRAPERQEEAPPPSEDA--------------SNGREPKAPTSDKCLPH 637
Query: 920 AECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSC 979
+ +G A +Q P L P +G S + A SC
Sbjct: 638 TSGSQVDTASGLQGEAGVAGQQEPEARELHAGSPPAHEAPQALSGSSSST------AGSC 691
Query: 980 SSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQ 1039
SS + P+AT + Q +R + + + RL SG
Sbjct: 692 SSDKM-----------GPEAAPAATHAAPQATREKIRSRFHGSHD--LIHRLFVCISGVA 738
Query: 1040 QEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPDS-ESNLDQNCLSRCSTEIF 1098
+++T +L+S L++ + + D +++ + + S ++C T
Sbjct: 739 DQLQT--NYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSS 796
Query: 1099 SEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVP 1158
SE + + D + W+PD C AC + F + RKHHCR+CG +FCS C + P
Sbjct: 797 SELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAP 856
Query: 1159 VPSQQLFEPSRVCKSCY 1175
+P +P RVC CY
Sbjct: 857 LPRYGQVKPVRVCTHCY 873
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 78.6 bits (192), Expect = 3e-14
Identities = 33/69 (47%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
WL D A HC C+ F L+ RKHHCRNCG +FC++C + ++P+PS +P RVC SC+
Sbjct: 572 WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSP--KPVRVCDSCH 629
Query: 1176 SSLHPTSSS 1184
+ L SS
Sbjct: 630 ALLIQRCSS 638
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 72.4 bits (176), Expect = 2e-12
Identities = 28/63 (44%), Positives = 35/63 (55%)
Query: 1112 EMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVC 1171
E +W+PD C CD+ F +RKHHCR CG FC CC+QKVP+ +P R C
Sbjct: 37 EEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQC 96
Query: 1172 KSC 1174
C
Sbjct: 97 AEC 99
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 68.2 bits (165), Expect = 5e-11
Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 1039 QQEVETLKKQVQELKSRL-------------ESQYLTSSLHFNGDFGDEVTSIPDSESNL 1085
Q+ V L+KQ +L+ + L L G+ T + + + L
Sbjct: 1261 QRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL 1320
Query: 1086 DQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCG 1145
D + E+ E Q+ +W D+ +C AC F + R+HHCR CG
Sbjct: 1321 DNT--TAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCG 1378
Query: 1146 NVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSL 1178
N+FC+ C + PS + +P RVC +C++ L
Sbjct: 1379 NIFCAECSAKNALTPSSK--KPVRVCDACFNDL 1409
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 67.8 bits (164), Expect = 6e-11
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 1109 QDTEMTR-WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEP 1167
QD+++ + W+PD CY C F R+HHCR CG +FCS CCNQ++P
Sbjct: 147 QDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGD 206
Query: 1168 SRVCKSC----YSSLHPTSSS 1184
R C C S H T S+
Sbjct: 207 LRACTYCRKIALSYAHSTDSN 227
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 67.4 bits (163), Expect = 8e-11
Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
W+PD A +C C F R+HHCR CG VFC CCN+K + Q L + +RVC CY
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCY 801
Query: 1176 SSL 1178
++
Sbjct: 802 ETI 804
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 67.4 bits (163), Expect = 8e-11
Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
W+PD A +C C F R+HHCR CG VFC CCN+K + Q L + +RVC CY
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCY 801
Query: 1176 SSL 1178
++
Sbjct: 802 ETI 804
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 65.5 bits (158), Expect = 3e-10
Identities = 28/63 (44%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
W+PD A +C C++ F R+HHCR CG VFC+SCC+ K + E +RVC C+
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKE-ARVCVICH 754
Query: 1176 SSL 1178
S L
Sbjct: 755 SVL 757
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,502,526
Number of Sequences: 37866
Number of extensions: 2554001
Number of successful extensions: 10712
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 10404
Number of HSP's gapped (non-prelim): 351
length of query: 1198
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1084
effective length of database: 13,930,794
effective search space: 15100980696
effective search space used: 15100980696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.