Search of human proteins with 239748995

Search of human proteins with 239748995

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239748995 PREDICTED: hypothetical protein XP_002346877 [Homo
sapiens]
         (326 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239748995 PREDICTED: hypothetical protein XP_002346877 [Homo ...   682   0.0  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    60   2e-09
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   50   2e-06
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   50   3e-06
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   50   3e-06
gi|157785645 SPEG complex locus [Homo sapiens]                         50   4e-06
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   49   5e-06
gi|157364934 fibrosin [Homo sapiens]                                   49   5e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     49   8e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   2e-05
gi|45120119 microtubule associated serine/threonine kinase 1 [Ho...    47   2e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   2e-05
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]            47   2e-05
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]             47   2e-05
gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]            47   3e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                47   3e-05
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            45   7e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    45   7e-05
gi|239756545 PREDICTED: hypothetical protein XP_002344931 [Homo ...    45   9e-05
gi|239751065 PREDICTED: hypothetical protein XP_002347692 [Homo ...    45   9e-05
gi|239745511 PREDICTED: hypothetical protein XP_002343508 [Homo ...    45   9e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     45   1e-04
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     45   1e-04
gi|56549694 enabled homolog isoform a [Homo sapiens]                   45   1e-04
gi|39930375 enabled homolog isoform b [Homo sapiens]                   45   1e-04
gi|239757559 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ...    45   1e-04
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ...    45   1e-04
gi|91208420 bassoon protein [Homo sapiens]                             45   1e-04
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       45   1e-04

>gi|239748995 PREDICTED: hypothetical protein XP_002346877 [Homo
           sapiens]
          Length = 326

 Score =  682 bits (1761), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MLEIHQTAEKDLLPPYSFFICKNVDFCFSDYAHSLFISYCGFIPSRNTDAIAKEAFRARL 60
           MLEIHQTAEKDLLPPYSFFICKNVDFCFSDYAHSLFISYCGFIPSRNTDAIAKEAFRARL
Sbjct: 1   MLEIHQTAEKDLLPPYSFFICKNVDFCFSDYAHSLFISYCGFIPSRNTDAIAKEAFRARL 60

Query: 61  TLPLLFAKPLRSGLATICFQNNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPA 120
           TLPLLFAKPLRSGLATICFQNNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPA
Sbjct: 61  TLPLLFAKPLRSGLATICFQNNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPA 120

Query: 121 WRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADA 180
           WRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADA
Sbjct: 121 WRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADA 180

Query: 181 AARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSR 240
           AARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSR
Sbjct: 181 AARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSR 240

Query: 241 LPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAG 300
           LPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAG
Sbjct: 241 LPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAG 300

Query: 301 PAPPLGLPSLLCADPHRPAFGSSPLP 326
           PAPPLGLPSLLCADPHRPAFGSSPLP
Sbjct: 301 PAPPLGLPSLLCADPHRPAFGSSPLP 326


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 71/254 (27%), Positives = 96/254 (37%), Gaps = 28/254 (11%)

Query: 91  PRGASPAWPGPPTPARRPVGAHACPRRLPAWRV----QGSSPPCC-FPASQQIT-NTERS 144
           P G  P  PGPP+P R  V A   P   PA ++    +GS+  C   PA+  +    E +
Sbjct: 97  PGGGGPQRPGPPSPRRPLVPAGPAP---PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153

Query: 145 HGGDGRGVARASLGDKAGAGRA-----GRGRPAQSPAEADAAARASKSLKLLSS--ALPP 197
             G  +    A+L  +AG G       G G     PA   AA   + S  LL+S  A  P
Sbjct: 154 PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAP 213

Query: 198 HLRPAAKTRAVAGPTAKESPPA--LRT---VGDGPRPGPKRPDPAPSRLPPPPHAGALRG 252
            +       A   P  K + P   ++T   VG    P P  P P  +  P  P A     
Sbjct: 214 AVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP 273

Query: 253 PPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLC 312
           PP P  L R      G   A   V    + +   +A  A         PAP  G P+ + 
Sbjct: 274 PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA-------PAPAPAAGGPAGVS 326

Query: 313 ADPHRPAFGSSPLP 326
             P   A  ++P P
Sbjct: 327 GQPGPGAAAAAPAP 340



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 45/148 (30%), Positives = 59/148 (39%), Gaps = 16/148 (10%)

Query: 96  PAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARA 155
           PA P P  PA  P      P  L       + PP   PA   +     +  G   G A A
Sbjct: 258 PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA---VPPPAAAQNGGSAGAAPA 314

Query: 156 ---SLGDKAG-AGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGP 211
              + G  AG +G+ G G  A +PA    A    +S K +  A PP    AA+T A +GP
Sbjct: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKA----ESPKRVVQAAPP----AAQTLAASGP 366

Query: 212 TAKESPPALRTVGDGPRPGPKR-PDPAP 238
            +  +   +     G  P P   P PAP
Sbjct: 367 ASTAASMVIGPTMQGALPSPAAVPPPAP 394



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 52/167 (31%), Positives = 59/167 (35%), Gaps = 29/167 (17%)

Query: 156 SLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSS--ALPPHLRPAAKTRAVAGPTA 213
           SL  +  A  A     A    E  AAA  +    ++S   A      PAA      G  A
Sbjct: 28  SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPG-AA 86

Query: 214 KESPPALRTVGDGPRPGPKRPDPAPSRLP-----PPPHAGALRGPPLPHRLRRSHFREVG 268
            E PPA R    G   GP+RP P   R P     P P A  LR PP              
Sbjct: 87  PEPPPAGRARPGG--GGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP----------EGSA 134

Query: 269 GGCAD----SVVLAEPSREQAHAAPPAWRTRV-----PGAGPAPPLG 306
           G CA     + V A P    A  A PA    +     PG GP P  G
Sbjct: 135 GSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 38/142 (26%), Positives = 46/142 (32%), Gaps = 27/142 (19%)

Query: 169 GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPR 228
           G PA  P  A A    + +    S+   P   PAA      GP      P        P 
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA-----GGPAGVSGQPGPGAAAAAPA 339

Query: 229 PGPKRPDP--APSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAH 286
           PG K   P       PP     A  GP                  A S+V+  P+ + A 
Sbjct: 340 PGVKAESPKRVVQAAPPAAQTLAASGP---------------ASTAASMVIG-PTMQGAL 383

Query: 287 AAPPAWRTRVPGAGPAPPLGLP 308
            +P A    VP   P  P GLP
Sbjct: 384 PSPAA----VPPPAPGTPTGLP 401



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 5/82 (6%)

Query: 173 QSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPK 232
           Q P    + A  + +  +LSS++    R A KT A    T+   PP L           K
Sbjct: 680 QQPPPPTSQATTALTAVVLSSSVQ---RTAGKTAATV--TSALQPPVLSLTQPTQVGVGK 734

Query: 233 RPDPAPSRLPPPPHAGALRGPP 254
           +  P P  +  PP  GAL  PP
Sbjct: 735 QGQPTPLVIQQPPKPGALIRPP 756



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 22/59 (37%), Positives = 24/59 (40%), Gaps = 6/59 (10%)

Query: 268 GGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
           G   A     AE +   A   PPA R R  G GP  P G PS     P RP   + P P
Sbjct: 69  GAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRP-GPPS-----PRRPLVPAGPAP 121


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 49/169 (28%), Positives = 63/169 (37%), Gaps = 31/169 (18%)

Query: 169  GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA--KESPPALRTVGDG 226
            G  A+  A+ D           +   LP HL+P++ +     P++  + SP    T+ +G
Sbjct: 1000 GEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG 1059

Query: 227  PRPG-PKRPDPAPSRLPPPPHA-----GALRGPPLPHRLRRSHFREVGGGCADSVVLAEP 280
            P P  P RP  APSR P PP A      A    PLP +              D     EP
Sbjct: 1060 PVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQK--------------DPAQPLEP 1105

Query: 281  SREQAHAAPPAWRTRVPGAGPAPPLGLP---SLLCADPHRPAFGSSPLP 326
             R      PP  R   P   PAPP   P         P R  FG+   P
Sbjct: 1106 KR------PPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSP 1148



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 40/163 (24%), Positives = 60/163 (36%), Gaps = 20/163 (12%)

Query: 92   RGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGD-GR 150
            R A P  P PP+ AR P       +   A +  G++       SQ       +  G  G 
Sbjct: 1119 RPAPPQRPPPPSGARSPAPTR---KEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1175

Query: 151  GVARASLGDKAGA-------GRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAA 203
              AR ++  +AG         RA  GR   +P      +  SK     S+ LP  L+P A
Sbjct: 1176 STARPTIPPRAGVISAPQSHARASAGR--LTPESQSKTSETSKG----STFLPEPLKPQA 1229

Query: 204  ---KTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPP 243
                  ++  P  +   P +      P+ GP+     P + PP
Sbjct: 1230 AFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1272



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 41/156 (26%), Positives = 48/156 (30%), Gaps = 34/156 (21%)

Query: 197  PHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKR--------PDPAPSRLPPPPHAG 248
            P  RPA   R      A+   P  +  G    PG  R        P P      P P   
Sbjct: 1116 PPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1175

Query: 249  ALRGPPLPHR-----LRRSHFREVGGGCA------------DSVVLAEPSREQA------ 285
            +   P +P R       +SH R   G                S  L EP + QA      
Sbjct: 1176 STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1235

Query: 286  HAAPPAWRTR---VPGAGPAPPLGLPSLLCADPHRP 318
               PPA R +   VP A P P  G    L   P  P
Sbjct: 1236 SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPP 1271


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 48/166 (28%), Positives = 62/166 (37%), Gaps = 36/166 (21%)

Query: 169  GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA--KESPPALRTVGDG 226
            G  A+  A+ D           +   LP HL+P++ +     P++  + SP    T+ +G
Sbjct: 1039 GEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG 1098

Query: 227  PRPG-PKRPDPAPSRLPPPPHA-----GALRGPPLPHRLRRSHFREVGGGCADSVVLAEP 280
            P P  P RP  APSR P PP A      A    PLP +              D     EP
Sbjct: 1099 PVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQK--------------DPAQPLEP 1144

Query: 281  SREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
             R      PP  R   P   PAPP          P  P+   SP P
Sbjct: 1145 KR------PPPPRPVAPPTRPAPP--------QRPPPPSGARSPAP 1176



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 42/159 (26%), Positives = 60/159 (37%), Gaps = 38/159 (23%)

Query: 161  AGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPA-AKTRAVAGPTAKESP-- 217
            +G G +    P  SP ++   +           +LP  +RP+ A +R    P+A+ SP  
Sbjct: 1075 SGLGTSPSSSPRTSPCQSPTISEGPVP------SLP--IRPSRAPSRTPGPPSAQSSPID 1126

Query: 218  --PALRTVGDGP-------RPGPKRP-----DPAPSRLPPPPHA-----------GALRG 252
              PA       P       RP P RP      PAP + PPPP             G +  
Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGA 1186

Query: 253  PPLPHRLRRSHFREVGGGCA--DSVVLAEPSREQAHAAP 289
            PP P   RR        G    D++  ++PS +   A P
Sbjct: 1187 PPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGP 1225



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 44/178 (24%), Positives = 63/178 (35%), Gaps = 34/178 (19%)

Query: 92   RGASPAWPGPPTPARRPV------GAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSH 145
            R A P  P PP+ AR P       G    P      R +  +P    P + +  N  RS 
Sbjct: 1158 RPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKS--PGTTRKDNIGRSQ 1215

Query: 146  ----------GGDGRGVARASLGDKAGA-------GRAGRGRPAQSPAEADAAARASKSL 188
                      G  G   AR ++  +AG         RA  GR   +P      +  SK  
Sbjct: 1216 PSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR--LTPESQSKTSETSKG- 1272

Query: 189  KLLSSALPPHLRPAA---KTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPP 243
               S+ LP  L+P A      ++  P  +   P +      P+ GP+     P + PP
Sbjct: 1273 ---STFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1327


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 48/166 (28%), Positives = 62/166 (37%), Gaps = 36/166 (21%)

Query: 169  GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA--KESPPALRTVGDG 226
            G  A+  A+ D           +   LP HL+P++ +     P++  + SP    T+ +G
Sbjct: 1039 GEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG 1098

Query: 227  PRPG-PKRPDPAPSRLPPPPHA-----GALRGPPLPHRLRRSHFREVGGGCADSVVLAEP 280
            P P  P RP  APSR P PP A      A    PLP +              D     EP
Sbjct: 1099 PVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQK--------------DPAQPLEP 1144

Query: 281  SREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
             R      PP  R   P   PAPP          P  P+   SP P
Sbjct: 1145 KR------PPPPRPVAPPTRPAPP--------QRPPPPSGARSPAP 1176



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 42/159 (26%), Positives = 60/159 (37%), Gaps = 38/159 (23%)

Query: 161  AGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPA-AKTRAVAGPTAKESP-- 217
            +G G +    P  SP ++   +           +LP  +RP+ A +R    P+A+ SP  
Sbjct: 1075 SGLGTSPSSSPRTSPCQSPTISEGPVP------SLP--IRPSRAPSRTPGPPSAQSSPID 1126

Query: 218  --PALRTVGDGP-------RPGPKRP-----DPAPSRLPPPPHA-----------GALRG 252
              PA       P       RP P RP      PAP + PPPP             G +  
Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGA 1186

Query: 253  PPLPHRLRRSHFREVGGGCA--DSVVLAEPSREQAHAAP 289
            PP P   RR        G    D++  ++PS +   A P
Sbjct: 1187 PPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGP 1225



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 44/178 (24%), Positives = 63/178 (35%), Gaps = 34/178 (19%)

Query: 92   RGASPAWPGPPTPARRPV------GAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSH 145
            R A P  P PP+ AR P       G    P      R +  +P    P + +  N  RS 
Sbjct: 1158 RPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKS--PGTTRKDNIGRSQ 1215

Query: 146  ----------GGDGRGVARASLGDKAGA-------GRAGRGRPAQSPAEADAAARASKSL 188
                      G  G   AR ++  +AG         RA  GR   +P      +  SK  
Sbjct: 1216 PSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR--LTPESQSKTSETSKG- 1272

Query: 189  KLLSSALPPHLRPAA---KTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPP 243
               S+ LP  L+P A      ++  P  +   P +      P+ GP+     P + PP
Sbjct: 1273 ---STFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1327


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 60/204 (29%), Positives = 79/204 (38%), Gaps = 33/204 (16%)

Query: 148  DGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAA------RASKSLKLLSSALPPHLRP 201
            + RG+ ++S   +  A   GR R A +P E   A       + S SL  LS A P     
Sbjct: 2121 ENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSS--- 2177

Query: 202  AAKTRAVAGPTAKESPPALRTVGDGPRP------GPKRPDPAP-----SRLPPPPHAGAL 250
             A+  A    T K + P+  T  D P+P        K P+P P     S+  PPP A   
Sbjct: 2178 PARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQT 2237

Query: 251  RGPPLPHRLRRSHFREVGGGC--ADSVVLAEPSREQAHAA---------PPAWRTRVPGA 299
               PL    +     ++ G          A PS  + HAA         P A   RVP A
Sbjct: 2238 LALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSA 2297

Query: 300  GPAPPLGLPSLLCADPHRPAFGSS 323
            G  P L   + +   P RP  GSS
Sbjct: 2298 GGPPVLAEKARVPTVPPRP--GSS 2319



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 35/133 (26%), Positives = 49/133 (36%), Gaps = 25/133 (18%)

Query: 92  RGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRG 151
           R  SP  PG P    RP    + P+   A     + PP   P+S +         GD  G
Sbjct: 523 RAPSPREPGEPPLFSRP----STPKTSRAVSPAAAQPPS--PSSAE-------KPGDEPG 569

Query: 152 VARASLGDKAGAGRAGRGRPAQSPAEA-----DAAARASKSLKLLSSALPPHLRPAAKTR 206
             R+        G AGR  P + P +            S++++   S +PP      + R
Sbjct: 570 RPRSR-------GPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEAR 622

Query: 207 AVAGPTAKESPPA 219
             A P  K  PPA
Sbjct: 623 TKAPPGRKREPPA 635


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 43/144 (29%), Positives = 56/144 (38%), Gaps = 28/144 (19%)

Query: 169  GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA--KESPPALRTVGDG 226
            G  A+  A+ D           +   LP HL+P++ +     P++  + SP    T+ +G
Sbjct: 995  GEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG 1054

Query: 227  PRPG-PKRPDPAPSRLPPPPHA-----GALRGPPLPHRLRRSHFREVGGGCADSVVLAEP 280
            P P  P RP  APSR P PP A      A    PLP +              D     EP
Sbjct: 1055 PVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQK--------------DPAQPLEP 1100

Query: 281  SREQAHAAPPAWRTRVPGAGPAPP 304
             R      PP  R   P   PAPP
Sbjct: 1101 KR------PPPPRPVAPPTRPAPP 1118



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 52/186 (27%), Positives = 63/186 (33%), Gaps = 44/186 (23%)

Query: 170  RPAQSPAEADAAARASKSLKLLSSALP-PHLRPAAKTRAVAGPTAKESPPALRTVGDGPR 228
            RP+++P+       A  S      A P P   PA        P   + PP  R V    R
Sbjct: 1062 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ-------PLEPKRPPPPRPVAPPTR 1114

Query: 229  PGPKRPDPAPS-RLPPPPHAG---------ALRGPPLPHR-----LRRSHFREVGGGCA- 272
            P P +  P PS R  P P AG         +   P +P R       +SH R   G    
Sbjct: 1115 PAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1174

Query: 273  -----------DSVVLAEPSREQA------HAAPPAWRTR---VPGAGPAPPLGLPSLLC 312
                        S  L EP + QA         PPA R +   VP A P P  G    L 
Sbjct: 1175 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1234

Query: 313  ADPHRP 318
              P  P
Sbjct: 1235 TPPQPP 1240



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 40/162 (24%), Positives = 53/162 (32%), Gaps = 9/162 (5%)

Query: 91   PRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGR 150
            P  A PA P P     +P+     P   P       +PP   P     +      G  G 
Sbjct: 1080 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGP 1139

Query: 151  GVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSA------LPPHLRPAA- 203
            G A  S        RAG     QS A A A     +S    S        LP  L+P A 
Sbjct: 1140 GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA 1199

Query: 204  --KTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPP 243
                 ++  P  +   P +      P+ GP+     P + PP
Sbjct: 1200 FPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1241


>gi|157364934 fibrosin [Homo sapiens]
          Length = 460

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 74/305 (24%), Positives = 100/305 (32%), Gaps = 38/305 (12%)

Query: 32  AHSLFISYCGFIPSRNTDAIAKEAFRARLTLPLLFAKPLRSGLATICFQNNGKVQQDRFP 91
           AH  F+S     PS + D   +    A L      +     GL +  F N+G V   +  
Sbjct: 160 AHGPFLS-----PSTHIDPFGRPTSFASLAA---LSNGAFGGLGSPTF-NSGAVFAQKES 210

Query: 92  RGASPAWPGPPTPARRPVGAHACPRRLPAW-------RVQGSSPPCCFPASQQITNTERS 144
            GA PA+  PP P  R    H  P   PAW       R  GS      P  ++  +  + 
Sbjct: 211 PGAPPAFASPPDPWGR---LHRSPLTFPAWVRPPEAARTPGSDKE--RPVERREPSITKE 265

Query: 145 HGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAK 204
                   +R  L       +A  G     P +     +  +  +  ++A       AA 
Sbjct: 266 EKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAA------AAAA 319

Query: 205 TRAVAGPTAKESPPALRTVGDGPRP----GPKRPDPAPSRLPPPPHAGALRGPPLPHRLR 260
             A A   A   P  L  + + PRP    GP  PD     L P   A        P   R
Sbjct: 320 AAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAP------PRLAR 373

Query: 261 RSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRV-PGAGPAPPLGLPSLLCADPHRPA 319
              F E G        +A         A P   +R+ P   PA   G P LL   P    
Sbjct: 374 PPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLSKTPPGAL 433

Query: 320 FGSSP 324
            G+ P
Sbjct: 434 LGAPP 438


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 71/259 (27%), Positives = 89/259 (34%), Gaps = 30/259 (11%)

Query: 14  PPYSFFICKNVDFCFSDYAHSLFISYCGFIPSRNTDAIAKEAFRARLTLPLLFAKPLR-S 72
           P Y  +I   +D   S  A       C  +  R+      E  RA L   +     LR S
Sbjct: 29  PHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPE--PERTRAELEKLIQQRAVLRVS 86

Query: 73  GLATICFQNNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCF 132
              +I ++N  +VQ  R  RGA+P     P P R P GA A              PP   
Sbjct: 87  YKGSISYRNAARVQPPR--RGATP-----PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP 139

Query: 133 PASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLS 192
            A+       R+        A  S G      RA R  P  +P  A AA           
Sbjct: 140 VAAAAPARAPRAAAA--AATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA----------- 186

Query: 193 SALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALR- 251
              PP + P A  R    P      P L      P P  ++  P P    PPP  GA+R 
Sbjct: 187 ---PPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQP-QPPPEGGAVRA 242

Query: 252 -GPPLPHRLRRSHFREVGG 269
            G   P  LR    R +GG
Sbjct: 243 GGAARPVSLREV-VRYLGG 260



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 52/180 (28%), Positives = 63/180 (35%), Gaps = 29/180 (16%)

Query: 69  PLRSGLATICFQNNGKVQQDRFPRGASPAWPGPPTPARRP-VGAHACPRRLPAWRVQGSS 127
           P  +  A     + G  Q     + A+P    PP PA  P V   A PRR P   V    
Sbjct: 149 PRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAARE 208

Query: 128 PPCC------FPASQQITNTERSHGGDGRGVARAS--------------LGDKAGAG-RA 166
           PP         P  QQ     +       G  RA               LG   GAG R 
Sbjct: 209 PPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRL 268

Query: 167 GRGRPAQSPAEADAAARAS-KSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGD 225
            RGR  Q   E +AAAR   +  +L + ALP   RP       A P A   P   +  G+
Sbjct: 269 TRGR-VQGLLEEEAAARGRLERTRLGALALPRGDRPGR-----APPAASARPSRSKRGGE 322


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 69/259 (26%), Positives = 91/259 (35%), Gaps = 56/259 (21%)

Query: 92  RGASPAWPGPPTPAR----RPVGAHA-CPRRLPAWRVQGSS--PPCCFPASQQITNTERS 144
           R  S   PG P+PA     R  G     PR  P+ R +  +  P     ++ + + TE S
Sbjct: 162 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221

Query: 145 HGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSL---------KLLSSAL 195
                R  A   L   A    +    P  SPA +  +AR +            K L +  
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281

Query: 196 PPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALR---G 252
           PP + P  K  A A      SP A       P P       AP  LP  PH+ +L     
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLAT------PSPSAALQSQAPPTLPATPHSSSLTCQLA 335

Query: 253 PPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPP------LG 306
            PLP                    LA PS     +APP+ +T +P     PP      LG
Sbjct: 336 TPLP--------------------LAPPS----PSAPPSLQT-LPSPPATPPSQATTSLG 370

Query: 307 LPSLLCADPHRPAFGSSPL 325
            P+L       P+   SPL
Sbjct: 371 SPTLQATHSFLPSPPLSPL 389



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 63/252 (25%), Positives = 83/252 (32%), Gaps = 51/252 (20%)

Query: 85  VQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERS 144
           VQ    P  + P  P    P++ P    A P ++P       SPP   P S   T   ++
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP------SPPASPPMSPSATPPPQA 501

Query: 145 HGGDG-------RGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPP 197
                       +   +A         +A    PA  P +A  +  AS  +  L++  PP
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP-PP 560

Query: 198 HLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKR--------------PDPAPSRLPP 243
              P      +  P +  + P L+     P PGP                P P PSR P 
Sbjct: 561 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP- 619

Query: 244 PPHAGALRGPPL----------PHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWR 293
              +  L GP L          P  LR       GG  A       P  E A   P AW 
Sbjct: 620 ---SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS----PPPDAELAACHPAAW- 671

Query: 294 TRVPGAGPAPPL 305
                 GPAPPL
Sbjct: 672 ----SRGPAPPL 679



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 65/246 (26%), Positives = 79/246 (32%), Gaps = 41/246 (16%)

Query: 95  SPAWPGPPTPAR-RPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVA 153
           SP  P P TPA  R +GA     R P     G       P S       RS G   R  A
Sbjct: 32  SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPA 91

Query: 154 R----ASLGDKAGAGRAGRGRPAQSPAEADAAAR----ASKSLKL----------LSSAL 195
                +  G++A   +     P  SP  A    R      K L++           + A 
Sbjct: 92  SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151

Query: 196 PPHLRPAAKTRAVAGPTAKESPPAL--RTVGDGPRPGPKRPDPAPSRLPPPPHAGALRG- 252
                 A   R  +GPT     PA+  R+   G   G   P PAPS  P PP  G  +  
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG--LPRPAPSARPRPPTEGPRKSV 209

Query: 253 ---------PPLPHRLRRSHFREVGGGCADSV-----VLAEPSREQAHAAPPAWRTRVPG 298
                     P P   RR      GGG            A P    A + P A  T    
Sbjct: 210 SSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 299 AGPAPP 304
           A P+ P
Sbjct: 267 AHPSQP 272



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 25/113 (22%)

Query: 197 PHLRPAAKTRAVAGPTAKESPPALRTVG-DGPRPGPKRPDPAPSRLPPPPHAGALRGPPL 255
           P   PA+   + +     ++PP+L       P   P  P  +PS  PPP     L  PPL
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510

Query: 256 PHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLP 308
                                LA+P  +    APPA  T    A P+PP   P
Sbjct: 511 Q--------------------LAKPPPQ----APPALATPPLQALPSPPASFP 539



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 39/148 (26%), Positives = 56/148 (37%), Gaps = 9/148 (6%)

Query: 178 ADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPA 237
           A  +  A  SL+ L S  PP   P+  T ++  PT + +   L +    P   P  P  A
Sbjct: 341 APPSPSAPPSLQTLPS--PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP--PPQA 396

Query: 238 PSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVP 297
           P  L  PP    L+ PP P               A +  LA    +   + PP+   + P
Sbjct: 397 PPALALPP----LQAPPSPPASPPLSPLATPSPQAPN-ALAVHLLQAPFSPPPSPPVQAP 451

Query: 298 GAGPAPPLGLPSLLCADPHRPAFGSSPL 325
            + PA P   PS        P+  + PL
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPL 479



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 52/226 (23%), Positives = 74/226 (32%), Gaps = 24/226 (10%)

Query: 99  PGPPT------PARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGV 152
           P PP       P + P      P + P       SPP   P S   T + ++       +
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPP------SPPASPPLSPLATPSPQAPNALAVHL 435

Query: 153 ARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPT 212
            +A               P  SP  + +A   S++   L+ A P  + P+        P+
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPS 494

Query: 213 AKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCA 272
           A   P A   +   P    K P  AP  L  PP   AL  PP       + F        
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP-LQALPSPP-------ASFPGQAPFSP 546

Query: 273 DSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADPHRP 318
            + +   P       APP     +    P+PP   P+L    P RP
Sbjct: 547 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQA--PRRP 589


>gi|45120119 microtubule associated serine/threonine kinase 1 [Homo
            sapiens]
          Length = 1570

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 72/257 (28%), Positives = 94/257 (36%), Gaps = 60/257 (23%)

Query: 86   QQDRFPRGASPAWPG----PPTPARR---PVGAHAC--PRRL-PAWRVQGSSPPCCFPAS 135
            Q+     GA P  P     PP  ++    P GA AC  PR   P  R       C     
Sbjct: 1334 QESPLSLGADPLLPEGASRPPVSSKEKESPGGAEACTPPRATTPGGRTLERDVGC---TR 1390

Query: 136  QQITNTERSHGGDGRGVARASL--------GDKAGAGRAGRG------RPAQSPAEADAA 181
             Q   TE   GG  R VA+A+L        G ++ +G AG         PA+  A+A   
Sbjct: 1391 HQSVQTEDGTGGMARAVAKAALSPVQEHETGRRSSSGEAGTPLVPIVVEPARPGAKAVVP 1450

Query: 182  ARASKSLKLLSSALP--PHLRPAAKTR------------AVAGPTAKESPPALRTVGDGP 227
                   K L    P  P +  A + R             ++GP +K + P L       
Sbjct: 1451 QPLGADSKGLQEPAPLAPSVPEAPRGRERWVLEVVEERTTLSGPRSKPASPKLS------ 1504

Query: 228  RPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHA 287
             P P+ P  AP++   P  A     P  P  L       +G G    V L   SR  A A
Sbjct: 1505 -PEPQTPSLAPAKCSAPSSAVT---PVPPASL-------LGSGTKPQVGLT--SRCPAEA 1551

Query: 288  APPAWRTRVPGAGPAPP 304
             PPA  T+   + PAPP
Sbjct: 1552 VPPAGLTKKGVSSPAPP 1568


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 61/231 (26%), Positives = 85/231 (36%), Gaps = 23/231 (9%)

Query: 92  RGASPAWPGPPTPAR----RPVGAHA-CPRRLPAWRVQGSS--PPCCFPASQQITNTERS 144
           R  S   PG P+PA     R  G     PR  P+ R +  +  P     ++ + + TE S
Sbjct: 162 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221

Query: 145 HGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAK 204
                R  A   L   A    +    P  SPA +  +AR +       S   P    A +
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281

Query: 205 TRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHF 264
              V  P  K++ PAL  +   P   P         +PPP +A      PLP  L  S  
Sbjct: 282 PPQVT-PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT----PLPATLPPS-- 334

Query: 265 REVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADP 315
                  A  + LA PS     +APP+ +T +P     PP   P  +   P
Sbjct: 335 ----PPLATPLPLAPPS----PSAPPSLQT-LPSPPATPPSQAPPSMTTPP 376



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 63/241 (26%), Positives = 79/241 (32%), Gaps = 47/241 (19%)

Query: 91  PRGASPAWPGPPTPARRPVGAHACP--RRLPAWRVQGSSPPCCFPASQQITNTERSHGGD 148
           P  A P    P  PA  P+   A P  R  P         P   PAS  ++   +     
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788

Query: 149 GRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAV 208
              +A   L       +A    PA  P +A  +  AS  +  L++  PP   P      +
Sbjct: 789 PPALATPPL-------QALPSPPASFPGQAPFSPSASLPMSPLATP-PPQAPPVLAAPLL 840

Query: 209 AGPTAKESPPALRTVGDGPRPGPKR--------------PDPAPSRLPPPPHAGALRGPP 254
             P +  + P L+     P PGP                P P PSR P    +  L GP 
Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP----SSTLSGPD 896

Query: 255 L----------PHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPP 304
           L          P  LR       GG  A       P  E A   P AW       GPAPP
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAAS----PPPDAELAACHPAAW-----SRGPAPP 947

Query: 305 L 305
           L
Sbjct: 948 L 948



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 56/224 (25%), Positives = 78/224 (34%), Gaps = 17/224 (7%)

Query: 91  PRGASPAWPGPPTPARRPVGAHA--CPRRLPAWRVQGS-SPPCCFPASQQITNTERSHGG 147
           P  ASP   G P+P   P+       P  L    +Q   SPP   P S   T + ++   
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655

Query: 148 DGRGVARASLGDKAGAGRAGRGRPAQSPAEADAA---ARASKSLKLLSSALPPHLRPAAK 204
               + +A               P  SP  + +A   ++A  SL      +PP    +  
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715

Query: 205 TRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHF 264
               A P  +  PP        P   P  P  +PS  PPP     L  PPL         
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL--------- 766

Query: 265 REVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLP 308
            +V      S+ ++ P  +    APPA  T    A P+PP   P
Sbjct: 767 -QVPPSPPASLPMS-PLAKPPPQAPPALATPPLQALPSPPASFP 808



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 59/245 (24%), Positives = 84/245 (34%), Gaps = 50/245 (20%)

Query: 94  ASPAWPGPPTPARRPVGAHAC---PRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGR 150
           +SPA  GP         AH     P+ L A R    +PP                    R
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--------------------R 289

Query: 151 GVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAG 210
             A  +LG  + +  A    P+ S  +A        +   L + LPP   P   T     
Sbjct: 290 KDAAPALGPLSSSPLA---TPSPSGTKARPVPPPDNAATPLPATLPPS--PPLATPLPLA 344

Query: 211 PTAKESPPALRTVGDGPRPGPKRPDPA----PSRLPPP---------PH---AGALRGPP 254
           P +  +PP+L+T+   P   P +  P+    P + PP          PH   + +L+ PP
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404

Query: 255 LPHRLRRSHFREVGGG----CADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSL 310
            P  L         G        S +   P + QA    P+     P    +PPL  P  
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP--PDSPPLQAPLS 462

Query: 311 LCADP 315
           L A P
Sbjct: 463 LPASP 467



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 30/226 (13%)

Query: 95  SPAWPGPPTPARRPVGAHACPRRLPAWR-VQGSSPPCCFPASQQIT-------NTERSHG 146
           SP+ P    P   P+ A   P  LPA   +Q S  P   P S  +T       ++  SH 
Sbjct: 443 SPSRPASTPPDSPPLQA---PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499

Query: 147 GDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTR 206
                  +A L          +   A    +   A+  +  L+ L S  PP L+ A+   
Sbjct: 500 ------PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS--- 550

Query: 207 AVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPP--LPHRLRRSHF 264
           A       E+PP        P P P +  P+P   PPP    ++  PP   P  L     
Sbjct: 551 APLTTPHLETPPC-------PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603

Query: 265 REVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAG-PAPPLGLPS 309
           + +       +    P      A PP      P A  P  PL  PS
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649


>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 51/187 (27%), Positives = 67/187 (35%), Gaps = 21/187 (11%)

Query: 113 ACPRRL---PAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRG 169
           +CP RL   PA      SPP    +  ++    +  GG G    R S+GD +      + 
Sbjct: 519 SCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQE 578

Query: 170 RPAQSPAEADAAARASKSLKLL-----SSALPPHLRPAAKTRAVAGPTAKESPPA-LRTV 223
                 A  D     S SL  +        L P   P   T+   GP + E PPA LR  
Sbjct: 579 AQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRAT 638

Query: 224 GDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSRE 283
           G GP    +  DP P          AL G P     +R       GG  +S  +   S+E
Sbjct: 639 GQGPL--AQLMDPGP----------ALPGSPANSHTQRDARARADGGGTESRPVLRYSKE 686

Query: 284 QAHAAPP 290
           Q     P
Sbjct: 687 QRPTTLP 693


>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 51/187 (27%), Positives = 67/187 (35%), Gaps = 21/187 (11%)

Query: 113 ACPRRL---PAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRG 169
           +CP RL   PA      SPP    +  ++    +  GG G    R S+GD +      + 
Sbjct: 519 SCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQE 578

Query: 170 RPAQSPAEADAAARASKSLKLL-----SSALPPHLRPAAKTRAVAGPTAKESPPA-LRTV 223
                 A  D     S SL  +        L P   P   T+   GP + E PPA LR  
Sbjct: 579 AQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRAT 638

Query: 224 GDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSRE 283
           G GP    +  DP P          AL G P     +R       GG  +S  +   S+E
Sbjct: 639 GQGPL--AQLMDPGP----------ALPGSPANSHTQRDARARADGGGTESRPVLRYSKE 686

Query: 284 QAHAAPP 290
           Q     P
Sbjct: 687 QRPTTLP 693


>gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 320

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 73/240 (30%), Positives = 90/240 (37%), Gaps = 49/240 (20%)

Query: 81  NNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITN 140
           N G + Q   PR    +      P RR    +  PRRLP    QGS   C F      T 
Sbjct: 7   NKGSIGQSAIPRFHLRS------PGRRGTAGNL-PRRLPL--AQGSPRCCRFCKGSVSTA 57

Query: 141 TERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLR 200
           T  S G    G A  +LG  A        R A +P  A  + RA   L+ L       LR
Sbjct: 58  TVTSSGASAPGSADPTLGSTAA-------RRASAPW-ASLSTRADSGLRHLD-----RLR 104

Query: 201 PAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGA--LRGPPLPHR 258
            AA+   V  P  + SP  +R+      P P R DP  S    P H G   L+ PP   R
Sbjct: 105 KAARLLFVNTPHVR-SPCPIRS------PLPAREDPPLS----PQHWGGEILKFPP---R 150

Query: 259 LRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADPHRP 318
            +R+   E G          E  +++     P    R P   PA    LP   CA P RP
Sbjct: 151 EKRASSAEPGHW--------EKRQDKRLETHPC---RAPPLPPARRSPLPRAACAHPRRP 199


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 45/154 (29%), Positives = 59/154 (38%), Gaps = 26/154 (16%)

Query: 171 PAQSPAEADAAARASKSLK-LLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRP 229
           PA +PA A A A AS + K    S +PP  RPA+       P    SPP      +    
Sbjct: 513 PAPAPAPAPAPALASAATKERTESEVPP--RPAS-------PKVTRSPPETAAPVEDMAR 563

Query: 230 GPKRPDPAPSRLPPPPHAGALRGPP----------------LPHRLRRSHFREVGGGCAD 273
             KRP PA   +PPP  +G+   PP                LP RL  S  R        
Sbjct: 564 RTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPL 623

Query: 274 SVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGL 307
                +P+R Q+  +P +     PG     P+ L
Sbjct: 624 PPTPPQPARRQSRRSPASPSPASPGPASPSPVSL 657



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 53/222 (23%), Positives = 75/222 (33%), Gaps = 30/222 (13%)

Query: 95  SPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVAR 154
           +PA    P PA  P  A A        R +   PP   PAS ++T +          +AR
Sbjct: 506 TPATTPAPAPAPAPAPAPALASAATKERTESEVPPR--PASPKVTRSPPETAAPVEDMAR 563

Query: 155 ASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPT-- 212
            +        R    RP   P +   +  +  +  L   +  P   P A  R + G +  
Sbjct: 564 RTK-------RPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGT-PQALPRRLVGSSLR 615

Query: 213 AKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCA 272
           A   PP L        P P +P    SR  P   + A  GP  P  +  S+  +V  G A
Sbjct: 616 APTVPPPLP-------PTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAA 668

Query: 273 DSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCAD 314
                       A    P   + VP     PP   P  L ++
Sbjct: 669 -----------TAEGGAPEAISGVPTPPAIPPQPRPRSLASE 699


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 42/133 (31%), Positives = 54/133 (40%), Gaps = 25/133 (18%)

Query: 197 PHLRPAAKTRA--VAGPTAKESPPALRTVGDGPRPGPKRPDPAP-SRLPPPP----HAGA 249
           PH + +   RA  + GP  ++ PP        PRP P RP   P +R PPPP    H G+
Sbjct: 17  PHSQVSLARRAPLMFGPGLRDPPP--------PRPAPPRPGEEPGNRHPPPPAARTHPGS 68

Query: 250 LRG---PPLPHRLRRSHFREVGGGCAD-SVVLAEPSREQAHAAPPAWRTRVPGAGPAPPL 305
            R     P    LR       G   AD     A P R++       W  R+PG+  AP  
Sbjct: 69  CRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQR------VWARRLPGSAAAPAP 122

Query: 306 GLPSLLCADPHRP 318
           G  +L    P  P
Sbjct: 123 GRDALRLPPPPPP 135



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 45/150 (30%), Positives = 54/150 (36%), Gaps = 17/150 (11%)

Query: 92  RGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSS--PPCCFPASQQITNTERSHGGDG 149
           R   P  P PP P   P   H  P   PA R    S    C  PA+  +    R      
Sbjct: 36  RDPPPPRPAPPRPGEEPGNRHPPP---PAARTHPGSCRARCPSPAAGGL----RGPWTAA 88

Query: 150 RGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVA 209
            G  RA  G  A      R    + P  A A A    +L+L     PP  RP      +A
Sbjct: 89  PGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLA 148

Query: 210 GPTAKESPPALRTVGDGPRPGPK-RPDPAP 238
           G  A  +PP+       P P P+ RP P P
Sbjct: 149 GGPADSAPPS-------PAPAPRSRPAPRP 171


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 48/178 (26%), Positives = 58/178 (32%), Gaps = 21/178 (11%)

Query: 143 RSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPA 202
           RS GG G G  R     + G G  G     +SP                   L  +  P 
Sbjct: 7   RSRGGGGGGFHR-----RGGGGGRGGLHDFRSPPPG--------------MGLNQNRGPM 47

Query: 203 AKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPP-PHAGALRGPPLPHRLRR 261
                 +GP     PP        P P    P   P   PPP P     + PP P +   
Sbjct: 48  GPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSS 107

Query: 262 SHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAP-PLGLPSLLCADPHRP 318
                 G G A  V  A P+   A  A P      PG+GP P P   P++  A P  P
Sbjct: 108 KPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP 165



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 34/116 (29%), Positives = 40/116 (34%), Gaps = 7/116 (6%)

Query: 196 PPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPP--PPHAGALRGP 253
           PPH +P  + +    P     P   +  G GP PG     PA S  PP  PP +GA  G 
Sbjct: 88  PPHPQPHQQQQPPPPPQDSSKPVVAQ--GPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145

Query: 254 ---PLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLG 306
              P P           G           P+       PP     VPG GP P  G
Sbjct: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 43/173 (24%), Positives = 61/173 (35%), Gaps = 26/173 (15%)

Query: 85  VQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERS 144
           + Q+R P G  P   GP  P   P   H   ++ P  +     PP   P      + ++ 
Sbjct: 40  LNQNRGPMGPGPGQSGPKPPIPPPP-PHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQ 98

Query: 145 HGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAK 204
                +  ++  +              AQ P  A     A  +    SS+ PP   P + 
Sbjct: 99  PPPPPQDSSKPVV--------------AQGPGPAPGVGSAPPA----SSSAPPATPPTSG 140

Query: 205 TRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLP-PPPHAGALRGPPLP 256
               +GP    +PP   T      PG   P P  S +P  PP AG   GPP P
Sbjct: 141 APPGSGPGPTPTPPPAVT---SAPPGAPPPTPPSSGVPTTPPQAG---GPPPP 187


>gi|239756545 PREDICTED: hypothetical protein XP_002344931 [Homo
           sapiens]
          Length = 427

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 51/180 (28%), Positives = 65/180 (36%), Gaps = 12/180 (6%)

Query: 102 PTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKA 161
           P PA RP      P    A  V GS  P    +    T+     G    G    S+GD A
Sbjct: 198 PGPAERPFPGEKGPPGAAASAVSGSWLPIMLESEAGGTDAAGQAGWRSPG---KSMGDAA 254

Query: 162 GAG--------RAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA 213
             G        R GRG   Q+P EA  +  +  + KL S    P    +  +    G T 
Sbjct: 255 APGGSLGNPRLRPGRGSANQTPGEAFPSPVSFSAAKLRSDRGGPSWSISELSVDPQGSTV 314

Query: 214 KESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPH-RLRRSHFREVGGGCA 272
           K+ P +L++    P   P      PS LP P         P PH R   SH      GC+
Sbjct: 315 KQIPSSLQSREVPPTDAPSLLASPPSGLPRPGTRWFRSFLPRPHSRPLSSHSLPSPKGCS 374


>gi|239751065 PREDICTED: hypothetical protein XP_002347692 [Homo
           sapiens]
          Length = 537

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 51/180 (28%), Positives = 65/180 (36%), Gaps = 12/180 (6%)

Query: 102 PTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKA 161
           P PA RP      P    A  V GS  P    +    T+     G    G    S+GD A
Sbjct: 308 PGPAERPFPGEKGPPGAAASAVSGSWLPIMLESEAGGTDAAGQAGWRSPG---KSMGDAA 364

Query: 162 GAG--------RAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA 213
             G        R GRG   Q+P EA  +  +  + KL S    P    +  +    G T 
Sbjct: 365 APGGSLGNPRLRPGRGSANQTPGEAFPSPVSFSAAKLRSDRGGPSWSISELSVDPQGSTV 424

Query: 214 KESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPH-RLRRSHFREVGGGCA 272
           K+ P +L++    P   P      PS LP P         P PH R   SH      GC+
Sbjct: 425 KQIPSSLQSREVPPTDAPSLLASPPSGLPRPGTRWFRSFLPRPHSRPLSSHSLPSPKGCS 484



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 41/156 (26%), Positives = 54/156 (34%), Gaps = 16/156 (10%)

Query: 146 GGDGRGVARASLGDKAGAGR---AGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPA 202
           GG  R ++      + G GR    G G   Q   +   ++    S  LL  +        
Sbjct: 216 GGGARAISPPPTVCRRGRGRLGWGGAGGQVQDVPDTQVSSDLYPSPYLLVGSPEGLQAEQ 275

Query: 203 AKTRAVAGPTAKESPPALRT------VGDGPRPGP-KRPDPAPSRLPPPPHAGALRGPPL 255
                V GP  +     L +       G  PRPGP +RP P   + PP   A A+ G  L
Sbjct: 276 MAGMGVLGPQVEALAGELSSWAQLWGEGQAPRPGPAERPFPG-EKGPPGAAASAVSGSWL 334

Query: 256 PHRLRRSHFREVGG-GCADSVVLAEPSREQAHAAPP 290
           P  L      E GG   A       P +    AA P
Sbjct: 335 PIMLE----SEAGGTDAAGQAGWRSPGKSMGDAAAP 366


>gi|239745511 PREDICTED: hypothetical protein XP_002343508 [Homo
           sapiens]
          Length = 427

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 51/180 (28%), Positives = 65/180 (36%), Gaps = 12/180 (6%)

Query: 102 PTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKA 161
           P PA RP      P    A  V GS  P    +    T+     G    G    S+GD A
Sbjct: 198 PGPAERPFPGEKGPPGAAASAVSGSWLPIMLESEAGGTDAAGQAGWRSPG---KSMGDAA 254

Query: 162 GAG--------RAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTA 213
             G        R GRG   Q+P EA  +  +  + KL S    P    +  +    G T 
Sbjct: 255 APGGSLGNPRLRPGRGSANQTPGEAFPSPVSFSAAKLRSDRGGPSWSISELSVDPQGSTV 314

Query: 214 KESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPH-RLRRSHFREVGGGCA 272
           K+ P +L++    P   P      PS LP P         P PH R   SH      GC+
Sbjct: 315 KQIPSSLQSREVPPTDAPSLLASPPSGLPRPGTRWFRSFLPRPHSRPLSSHSLPSPKGCS 374


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 43/158 (27%), Positives = 56/158 (35%), Gaps = 15/158 (9%)

Query: 169 GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPR 228
           G  A+   E + A +   SL   +  +PP +           P+    PPA    GD   
Sbjct: 537 GEVAKLTKELEDAKKEMASLSAAAITVPPSV-----------PSRAPVPPAPPLPGDSGT 585

Query: 229 PGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAA 288
             P  P P  S  PPPP       PPLP  +  S    + GG A    ++ P      A 
Sbjct: 586 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTA----ISPPPPLSGDAT 641

Query: 289 PPAWRTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
            P       G G   P  LP      P  P  GS+ +P
Sbjct: 642 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 679



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 24/132 (18%)

Query: 207 AVAGPTAKESPPALRTVGDGPRPGPKRPD----PAPSRLP-------PPPHAGALRGPPL 255
           ++ G TA   PP L      P P P  P+    P+PS LP       PPP  G+ R PP 
Sbjct: 623 SLPGGTAISPPPPLSGDATIPPP-PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681

Query: 256 PHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGA-GPAPPLGLPSLLCAD 314
           P  L          G A       P   +A   PP     +PG  G  PP   P      
Sbjct: 682 PPPL---------PGSAGIPPPPPPLPGEAGMPPPP--PPLPGGPGIPPPPPFPGGPGIP 730

Query: 315 PHRPAFGSSPLP 326
           P  P  G  P P
Sbjct: 731 PPPPGMGMPPPP 742



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 41/163 (25%), Positives = 51/163 (31%), Gaps = 21/163 (12%)

Query: 95  SPAWPGPPTPARRPVGAHAC---PRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRG 151
           +P  P PP P   P+    C   P  LP      S PP   P S   T        +G G
Sbjct: 598 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPP---PLSGDATIPPPPPLPEGVG 653

Query: 152 VARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGP 211
           +   S      +   G   P   P    A           S+ +PP   P         P
Sbjct: 654 IPSPS------SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL--------P 699

Query: 212 TAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPP 254
                PP    +  GP   P  P P    +PPPP    +  PP
Sbjct: 700 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 742



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 6/65 (9%)

Query: 192 SSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALR 251
           S+ +PP   P   +  +  P     PP L      P P P  P   P   PPPP  G   
Sbjct: 675 SARIPPPPPPLPGSAGIPPP-----PPPLPGEAGMPPPPPPLPG-GPGIPPPPPFPGGPG 728

Query: 252 GPPLP 256
            PP P
Sbjct: 729 IPPPP 733


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 43/158 (27%), Positives = 56/158 (35%), Gaps = 15/158 (9%)

Query: 169 GRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPR 228
           G  A+   E + A +   SL   +  +PP +           P+    PPA    GD   
Sbjct: 546 GEVAKLTKELEDAKKEMASLSAAAITVPPSV-----------PSRAPVPPAPPLPGDSGT 594

Query: 229 PGPKRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAA 288
             P  P P  S  PPPP       PPLP  +  S    + GG A    ++ P      A 
Sbjct: 595 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTA----ISPPPPLSGDAT 650

Query: 289 PPAWRTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
            P       G G   P  LP      P  P  GS+ +P
Sbjct: 651 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 688



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 24/132 (18%)

Query: 207 AVAGPTAKESPPALRTVGDGPRPGPKRPD----PAPSRLP-------PPPHAGALRGPPL 255
           ++ G TA   PP L      P P P  P+    P+PS LP       PPP  G+ R PP 
Sbjct: 632 SLPGGTAISPPPPLSGDATIPPP-PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690

Query: 256 PHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGA-GPAPPLGLPSLLCAD 314
           P  L          G A       P   +A   PP     +PG  G  PP   P      
Sbjct: 691 PPPL---------PGSAGIPPPPPPLPGEAGMPPPP--PPLPGGPGIPPPPPFPGGPGIP 739

Query: 315 PHRPAFGSSPLP 326
           P  P  G  P P
Sbjct: 740 PPPPGMGMPPPP 751



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 41/163 (25%), Positives = 51/163 (31%), Gaps = 21/163 (12%)

Query: 95  SPAWPGPPTPARRPVGAHAC---PRRLPAWRVQGSSPPCCFPASQQITNTERSHGGDGRG 151
           +P  P PP P   P+    C   P  LP      S PP   P S   T        +G G
Sbjct: 607 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPP---PLSGDATIPPPPPLPEGVG 662

Query: 152 VARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGP 211
           +   S      +   G   P   P    A           S+ +PP   P         P
Sbjct: 663 IPSPS------SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL--------P 708

Query: 212 TAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPP 254
                PP    +  GP   P  P P    +PPPP    +  PP
Sbjct: 709 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 751



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 6/65 (9%)

Query: 192 SSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALR 251
           S+ +PP   P   +  +  P     PP L      P P P  P   P   PPPP  G   
Sbjct: 684 SARIPPPPPPLPGSAGIPPP-----PPPLPGEAGMPPPPPPLPG-GPGIPPPPPFPGGPG 737

Query: 252 GPPLP 256
            PP P
Sbjct: 738 IPPPP 742


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 11/102 (10%)

Query: 157 LGDKAGA--GRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAK 214
           LGD + +  G     +PA++P++          L  L+   PP L P     +VA P   
Sbjct: 281 LGDSSASEPGLQAASQPAETPSQQGIV------LGPLAPPPPPPLPPGPAQASVALPPPP 334

Query: 215 ESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLP 256
             PP       GP P P  P P P+++PPPP       PPLP
Sbjct: 335 GPPPPPPLPSTGPPP-PPPPPPLPNQVPPPPPPPP--APPLP 373



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 17/81 (20%)

Query: 192 SSALPPHLRPAAKTRA-------VAGPTAKESPPAL------RTVGDGPRPGPKRPDPAP 238
           SSA  P L+ A++          V GP A   PP L       +V   P PGP  P P P
Sbjct: 284 SSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLP 343

Query: 239 SRLPPPPHAGALRGPPLPHRL 259
           S  PPPP       PPLP+++
Sbjct: 344 STGPPPPPP----PPPLPNQV 360


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 11/102 (10%)

Query: 157 LGDKAGA--GRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAK 214
           LGD + +  G     +PA++P++          L  L+   PP L P     +VA P   
Sbjct: 281 LGDSSASEPGLQAASQPAETPSQQGIV------LGPLAPPPPPPLPPGPAQASVALPPPP 334

Query: 215 ESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLP 256
             PP       GP P P  P P P+++PPPP       PPLP
Sbjct: 335 GPPPPPPLPSTGPPP-PPPPPPLPNQVPPPPPPPP--APPLP 373



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 17/81 (20%)

Query: 192 SSALPPHLRPAAKTRA-------VAGPTAKESPPAL------RTVGDGPRPGPKRPDPAP 238
           SSA  P L+ A++          V GP A   PP L       +V   P PGP  P P P
Sbjct: 284 SSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLP 343

Query: 239 SRLPPPPHAGALRGPPLPHRL 259
           S  PPPP       PPLP+++
Sbjct: 344 STGPPPPPP----PPPLPNQV 360


>gi|239757559 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 196

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 50/162 (30%), Positives = 66/162 (40%), Gaps = 20/162 (12%)

Query: 172 AQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGP 231
           A  PA     A  + S + + +A     R +AK  ++A  T + +P AL    D PRP  
Sbjct: 40  ASRPALPSVGAAPTSSARAVQAAS----RSSAKPGSIA--TLRGAPSALLCEWDPPRPCS 93

Query: 232 KRPDPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGC---ADSVVLAEP--SREQAH 286
            R   A     P   + A    PLP +L      E GGG    A  ++   P  +RE+  
Sbjct: 94  ARAATAAVSRGPRARSSACSRLPLPRKLTEP---ERGGGAQSQASQLIRPTPLGTRERPL 150

Query: 287 AAPP--AWRTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
           AAPP    R+R  G     P G   L    PH P     PLP
Sbjct: 151 AAPPGNCARSRREGPSRPAPTGAAPLAPPAPHAP----PPLP 188


>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
           sapiens]
          Length = 459

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 68/274 (24%), Positives = 90/274 (32%), Gaps = 44/274 (16%)

Query: 67  AKPLRSGLATICFQNNGKVQQDRFPR--GASP---AWPGPPTPAR--RPVGAHACPRRLP 119
           A  L+ G    C      +   R+P   G  P    W  P  P R   P       +R P
Sbjct: 63  AAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSP 122

Query: 120 AWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEAD 179
           A     +SP   F +++    T  +  G GR   R     ++ A   GR      P    
Sbjct: 123 A----RASPGGGFTSAEGKRKTRPAGRGGGR-TRRVVAAPESAAAAPGRSPSPADPGSTS 177

Query: 180 AAARASKSLKLLSSALPP-HLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAP 238
           +A R  ++ +    AL P H  P A                         PG      + 
Sbjct: 178 SATRVPRARRSSRRALQPRHAAPDA-------------------------PGAPSRSTSQ 212

Query: 239 SRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEP---SREQAHAA---PPAW 292
           +  PP P   A R P  P  L R+  RE+GG  A SV  +     S E+  A+   PP  
Sbjct: 213 ATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQV 272

Query: 293 RTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
            T  P     P  G        PH P     P P
Sbjct: 273 LTAEPREDATPGEGRLPDFEKQPHSPRERLDPPP 306


>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
           sapiens]
          Length = 459

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 68/274 (24%), Positives = 90/274 (32%), Gaps = 44/274 (16%)

Query: 67  AKPLRSGLATICFQNNGKVQQDRFPR--GASP---AWPGPPTPAR--RPVGAHACPRRLP 119
           A  L+ G    C      +   R+P   G  P    W  P  P R   P       +R P
Sbjct: 63  AAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSP 122

Query: 120 AWRVQGSSPPCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEAD 179
           A     +SP   F +++    T  +  G GR   R     ++ A   GR      P    
Sbjct: 123 A----RASPGGGFTSAEGKRKTRPAGRGGGR-TRRVVAAPESAAAAPGRSPSPADPGSTS 177

Query: 180 AAARASKSLKLLSSALPP-HLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAP 238
           +A R  ++ +    AL P H  P A                         PG      + 
Sbjct: 178 SATRVPRARRSSRRALQPRHAAPDA-------------------------PGAPSRSTSQ 212

Query: 239 SRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEP---SREQAHAA---PPAW 292
           +  PP P   A R P  P  L R+  RE+GG  A SV  +     S E+  A+   PP  
Sbjct: 213 ATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQV 272

Query: 293 RTRVPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
            T  P     P  G        PH P     P P
Sbjct: 273 LTAEPREDATPGEGRLPDFEKQPHSPRERLDPPP 306


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 27/201 (13%)

Query: 80   QNNGKVQQDRFPRGASPAWP-------------GPPTPARRPVGAHACPRRLPAWRVQGS 126
            Q+  K  QD     +SPA P             GP TPA   V    CP  LP   +  +
Sbjct: 1344 QHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAP--CPAGLPRGYMTPA 1401

Query: 127  SP--------PCCFPASQQITNTERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEA 178
            SP        P     S   + T  ++G     + +A  G  A AGRA R +P  +    
Sbjct: 1402 SPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSG-LAAAGRAAREKPLSASDGE 1460

Query: 179  DAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESPPALRTVG-DGPRPGPKRPDPA 237
                + S++    +S+ PP L P++ + +      K  P A        P P P    P 
Sbjct: 1461 GGTPQPSRAYSYFASSSPP-LSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPR 1519

Query: 238  PSRLPPPPHAGALRGPPLPHR 258
                P P    A +G   PHR
Sbjct: 1520 SPGAPTPSPMVA-QGTQTPHR 1539



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 46/180 (25%), Positives = 66/180 (36%), Gaps = 21/180 (11%)

Query: 83  GKVQQDRFPRGASPAWPGPPTP-ARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNT 141
           GK  Q+R  RG     PG P P +R+   A A     PA   Q ++PP     S Q    
Sbjct: 259 GKPDQER-SRG-----PGGPQPGSRQAETARATSVPGPA---QAAAPPEVGRVSPQPPQP 309

Query: 142 ERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRP 201
            +    + R  A  +    A A  AG G   Q+            +  L  ++    ++P
Sbjct: 310 TKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQP 369

Query: 202 AAKTRAVAGPT-----------AKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGAL 250
            A T+    P+           +KE+ P     G GP P P       +R+ P    GAL
Sbjct: 370 EADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGAL 429



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 64/300 (21%), Positives = 96/300 (32%), Gaps = 47/300 (15%)

Query: 25   DFCFSDYAHSLFISYCGFIPSRNTDAIAKEAFRARLTLPLLFAKPLRSGLATICFQNNGK 84
            D+      + L +  C     +  D  A  A  A  + P  F +P     A      +G 
Sbjct: 3010 DYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGG 3069

Query: 85   VQQDRFPRGASPAWPGPPT-PARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTER 143
              Q+ FP   +P +PGP T PA             PA+      P   +PA   + N + 
Sbjct: 3070 PTQNGFPAHQAPTYPGPSTYPA-------------PAF-----PPGASYPAEPGLPNQQ- 3110

Query: 144  SHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASK----SLKLLSSALPPHL 199
                     A    G  AG       +    P  AD+ A   K    SL  L   +P + 
Sbjct: 3111 ---------AFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNY 3161

Query: 200  RPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGALRGPPLPHRL 259
                    +A P    S     T   GP             +P     G++   P P   
Sbjct: 3162 ------EVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYP 3215

Query: 260  RRSHFREVGGGCADSVV----LAEPSREQAHAAPPAWRTRVPGAG----PAPPLGLPSLL 311
              SH+  +      + V    ++E +++    AP + R    G G    P    G P +L
Sbjct: 3216 SDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVL 3275



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 217 PPALRTVGDGPRPGP--KRPDPAPSRLPPPPHAGALRG---PPLP 256
           PP     G GP PGP   +P  AP+     P AGA R    PP+P
Sbjct: 17  PPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVP 61



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 58/240 (24%), Positives = 85/240 (35%), Gaps = 63/240 (26%)

Query: 93   GASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITNTERS-----HGG 147
            G   A P      R     H+ P   PA   +G      +P+S + +   R+     H  
Sbjct: 3663 GRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPG---YPSSAEYSQPSRASSAYHHAS 3719

Query: 148  DGRGVAR------ASLGDKA---------GAGRAGRGRPAQSPAE----ADAAARASKSL 188
            D +  +R      A+L  KA         G   A   + +QSP+     + AA+R  ++ 
Sbjct: 3720 DSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQ 3779

Query: 189  KL---LSSALPPHLRPAAKTRAVAGPTAKESPPALRTVGDGPRPGPKR---PDPAPSRLP 242
            +    L    P      A+ +  + PT + S PA       P+PGP     P PA     
Sbjct: 3780 QQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPA----- 3834

Query: 243  PPPHAGALRGPPLPHRLRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPA 302
                     GPP   +   S       G A +     P + +A  A PA     PG GPA
Sbjct: 3835 ---------GPPRAEQTNGSK------GTAKA-----PQQGRAPQAQPA-----PGPGPA 3869


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 59/210 (28%), Positives = 72/210 (34%), Gaps = 35/210 (16%)

Query: 80  QNNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQI- 138
           Q  G   Q R P    P  PGP  P R+       P       + G  PP   P  Q++ 
Sbjct: 451 QPAGPPAQQRPPPQGGPPQPGPG-PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP 509

Query: 139 --TNTERSHGGDG----RGVARASLGDKAGAGRAGRGRPAQSPA--------EADAAARA 184
             T+  +          +G  R S     G G     RP  SP+        +A      
Sbjct: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSV 569

Query: 185 SKSLKLLSSALPPHLR-----------PAAKTRAV--AGPTAKESPPAL---RTVGDGPR 228
           S      +S  PP  +           PA  TR    AGP  +  PP     R  G GP 
Sbjct: 570 SGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPA 629

Query: 229 PGPKRPDPA--PSRLPPPPHAGALRGPPLP 256
             PK P  A  PS+  PPP   A  GPP P
Sbjct: 630 GRPK-PQLAQKPSQDVPPPATAAAGGPPHP 658



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 29/124 (23%)

Query: 209 AGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPP---HAGAL---RGPPLPHRL--- 259
           AGP A++ PP  +     P PGP+R  P   + PPP    H   L    G PLP RL   
Sbjct: 453 AGPPAQQRPPP-QGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511

Query: 260 -----------------RRSHFREVGGGCADSVVLAEPSRE--QAHAAPPAWRTRVPGAG 300
                            +    R V GG         P+    Q  A PP    +   +G
Sbjct: 512 TSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG 571

Query: 301 PAPP 304
           PAPP
Sbjct: 572 PAPP 575



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 62/236 (26%), Positives = 75/236 (31%), Gaps = 40/236 (16%)

Query: 103 TPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQ----QITNTERSHGGDGRGVARASLG 158
           +P R   G    P  LP  R Q S  P   PA Q    Q    +   G   +G       
Sbjct: 427 SPGRGSHGQTPSPGALPLGR-QTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485

Query: 159 DKAGAGR-AGRGRPAQSPAEADAAARASKSLKLLSSALPPHLRPAAKTRAVAGPTAKESP 217
              G    +G G PA SP      +  S   +  S A PP      ++R VAG       
Sbjct: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG------- 538

Query: 218 PALRTVGDGPRPGPKRP-DPAPSRLPPPPHAGALRGPPLPHRLRRSHFREVGGGCADSVV 276
                 G G  P  + P  P+P R   PP A              +    V G       
Sbjct: 539 ------GPGAPPAARPPASPSPQRQAGPPQA--------------TRQTSVSGPAPPKAS 578

Query: 277 LAEPSREQAHAAP-----PAWRTR-VPGAGPAPPLGLPSLLCADPHRPAFGSSPLP 326
            A P  +Q    P     PA  TR    AGP P  G P+     P  P     P P
Sbjct: 579 GAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP 634


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,092,475
Number of Sequences: 37866
Number of extensions: 1220949
Number of successful extensions: 14871
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 226
Number of HSP's successfully gapped in prelim test: 1258
Number of HSP's that attempted gapping in prelim test: 9271
Number of HSP's gapped (non-prelim): 4754
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.