Guide to the Human Genome
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Search of human proteins with 239747318

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747318 PREDICTED: similar to protein phosphatase 2,
catalytic subunit, alpha [Homo sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly...   537   e-153
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly...   537   e-153
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly...   518   e-147
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo...   274   6e-74
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo...   271   4e-73
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor...   271   4e-73
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]    205   4e-53
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ...   194   6e-50
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H...   181   4e-46
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ...   181   7e-46
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof...   122   2e-28
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo...   121   5e-28
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo...   121   5e-28
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo...   118   4e-27
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor...   118   4e-27
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof...   108   3e-24
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso...   107   8e-24
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso...   107   8e-24
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo...   107   8e-24
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof...   102   4e-22
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof...   102   4e-22
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo...   102   4e-22
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom...    98   6e-21
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]     86   4e-17
gi|23312374 protein phosphatase with EF hand calcium-binding dom...    55   8e-08
gi|23312378 protein phosphatase with EF hand calcium-binding dom...    50   2e-06
gi|23312380 protein phosphatase with EF hand calcium-binding dom...    48   9e-06
gi|23312386 serine/threonine protein phosphatase with EF-hand mo...    44   2e-04
gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]            30   1.6  
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ...    30   1.6  

>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  537 bits (1383), Expect = e-153
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
           MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60

Query: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
           KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120

Query: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
           PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180

Query: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
           EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240

Query: 241 HCGVPLLLFSLLLQ 254
           HCGVPLLLFSLLLQ
Sbjct: 241 HCGVPLLLFSLLLQ 254


>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  537 bits (1383), Expect = e-153
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
           MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60

Query: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
           KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120

Query: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
           PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180

Query: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
           EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240

Query: 241 HCGVPLLLFSLLLQ 254
           HCGVPLLLFSLLLQ
Sbjct: 241 HCGVPLLLFSLLLQ 254


>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 384

 Score =  518 bits (1333), Expect = e-147
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
           MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 122 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 181

Query: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
           KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 182 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 241

Query: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
           PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 242 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 301

Query: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
           EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 302 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 361

Query: 241 HCG 243
           HCG
Sbjct: 362 HCG 364


>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
           [Homo sapiens]
          Length = 309

 Score =  274 bits (700), Expect = 6e-74
 Identities = 144/248 (58%), Positives = 163/248 (65%), Gaps = 55/248 (22%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
           L   +VKSLC++AKEILT+ESN QEV CPVTV GD HGQ                     
Sbjct: 23  LSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82

Query: 90  -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 147
            GDY+DRGYYS+E V LL+A+KV Y E +TIL  NHESRQITQVY  Y+ECLRK+GNAN 
Sbjct: 83  MGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANV 142

Query: 148 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
                            DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202

Query: 192 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
           PDD                 D  ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS 
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

Query: 236 PNYCYHCG 243
           PNYCY CG
Sbjct: 263 PNYCYRCG 270


>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  271 bits (693), Expect = 4e-73
 Identities = 142/248 (57%), Positives = 163/248 (65%), Gaps = 55/248 (22%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
           L   +V++LC++AKEILT+ESN QEV CPVTV GD HGQ                     
Sbjct: 23  LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82

Query: 90  -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 147
            GDY+DRGYYS+E V LL+A+KV Y E +TIL  NHESRQITQVY  Y+ECLRK+GNAN 
Sbjct: 83  MGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANV 142

Query: 148 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
                            DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202

Query: 192 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
           PDD                 D  ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS 
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

Query: 236 PNYCYHCG 243
           PNYCY CG
Sbjct: 263 PNYCYRCG 270


>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  271 bits (693), Expect = 4e-73
 Identities = 142/248 (57%), Positives = 163/248 (65%), Gaps = 55/248 (22%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
           L   +V++LC++AKEILT+ESN QEV CPVTV GD HGQ                     
Sbjct: 23  LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82

Query: 90  -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 147
            GDY+DRGYYS+E V LL+A+KV Y E +TIL  NHESRQITQVY  Y+ECLRK+GNAN 
Sbjct: 83  MGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANV 142

Query: 148 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
                            DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202

Query: 192 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
           PDD                 D  ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS 
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

Query: 236 PNYCYHCG 243
           PNYCY CG
Sbjct: 263 PNYCYRCG 270


>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
          Length = 307

 Score =  205 bits (521), Expect = 4e-53
 Identities = 109/244 (44%), Positives = 146/244 (59%), Gaps = 55/244 (22%)

Query: 55  KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 92
           +VK+LC +A+EIL EESN Q V  PVTV GD HGQ                      GD+
Sbjct: 24  EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83

Query: 93  IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 144
           +DRG+YS+E  +LLLA+KV Y + +T++  NHESRQITQVY  Y+ECLRK+G        
Sbjct: 84  VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143

Query: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 194
                    +A  DG++FC+HGGLSPS+ TL  IRT++  Q++PH+GPM DLL+SDP+D 
Sbjct: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203

Query: 195 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
                           D    FN A+ + ++ RAHQLVM G+ W  +  V+ ++S PNYC
Sbjct: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263

Query: 240 YHCG 243
           Y CG
Sbjct: 264 YRCG 267


>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
           [Homo sapiens]
          Length = 283

 Score =  194 bits (493), Expect = 6e-50
 Identities = 102/226 (45%), Positives = 132/226 (58%), Gaps = 33/226 (14%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 110
           L    +K LC    ++L EESN Q V  PVTV GD HGQGD++DRGYYS+E    LLA+K
Sbjct: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78

Query: 111 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 153
             + + +T+L  NHESRQITQVY  Y+EC  K+GNAN                  D Q+ 
Sbjct: 79  AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138

Query: 154 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 197
           C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SDP+D DT                
Sbjct: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198

Query: 198 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243
              F H + L+L+ RAHQLV  G+ +  D  +V ++S PNYCY CG
Sbjct: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 244


>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
           sapiens]
          Length = 305

 Score =  181 bits (460), Expect = 4e-46
 Identities = 102/248 (41%), Positives = 132/248 (53%), Gaps = 55/248 (22%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
           L    +K LC    ++L EESN Q V  PVTV GD HGQ                     
Sbjct: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78

Query: 90  -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG 148
            GD++DRGYYS+E    LLA+K  + + +T+L  NHESRQITQVY  Y+EC  K+GNAN 
Sbjct: 79  MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138

Query: 149 -----------------DGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
                            D Q+ C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SD
Sbjct: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198

Query: 192 PDDHDT----------------PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
           P+D DT                   F H + L+L+ RAHQLV  G+ +  D  +V ++S 
Sbjct: 199 PEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSA 258

Query: 236 PNYCYHCG 243
           PNYCY CG
Sbjct: 259 PNYCYRCG 266


>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
           [Homo sapiens]
          Length = 342

 Score =  181 bits (458), Expect = 7e-46
 Identities = 108/270 (40%), Positives = 138/270 (51%), Gaps = 59/270 (21%)

Query: 29  GVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHG 88
           G  +    L P P P    L  L  R    LC    ++L EESN Q V  PVTV GD HG
Sbjct: 38  GAPAGRPFLSPGPPPVFHFLRFLKER----LCDYVCDLLLEESNVQPVSTPVTVCGDIHG 93

Query: 89  Q----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHES 126
           Q                      GD++DRGYYS+E    LLA+K  + + +T+L  NHES
Sbjct: 94  QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES 153

Query: 127 RQITQVYHSYEECLRKHGNANG-----------------DGQLFCLHGGLSPSVDTLHHI 169
           RQITQVY  Y+EC  K+GNAN                  D Q+ C+HGGLSP + TL  I
Sbjct: 154 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI 213

Query: 170 RTLNCLQKIPHEGPMGDLLYSDPDDHDT----------------PETFNHASGLRLVSRA 213
           RT+   Q+IPH+G   DL++SDP+D DT                   F H + L+L+ RA
Sbjct: 214 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 273

Query: 214 HQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243
           HQLV  G+ +  D  +V ++S PNYCY CG
Sbjct: 274 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 303


>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
           3 [Homo sapiens]
          Length = 341

 Score =  122 bits (307), Expect = 2e-28
 Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 59/265 (22%)

Query: 34  SASLLPTPAPKAAALDG----LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ 89
           S  L P  AP   +  G    L   +++ LC +++EI   +    E+  P+ + GD HGQ
Sbjct: 20  SRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQ 79

Query: 90  ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESR 127
                                 GDY+DRG  S+E + LLLA K+ Y E   +L  NHE  
Sbjct: 80  YYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECA 139

Query: 128 QITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLHHIRT 171
            I ++Y  Y+EC R++                  A  D ++FC HGGLSP + ++  IR 
Sbjct: 140 SINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRR 199

Query: 172 LNCLQKIPHEGPMGDLLYSDPD---------DHDTPETFN--------HASGLRLVSRAH 214
           +     +P +G + DLL+SDPD         D     TF         H   L L+ RAH
Sbjct: 200 IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAH 259

Query: 215 QLVMVGHNWCHDWNVVAIFSTPNYC 239
           Q+V  G+ +     +V +FS PNYC
Sbjct: 260 QVVEDGYEFFAKRQLVTLFSAPNYC 284


>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
           [Homo sapiens]
          Length = 323

 Score =  121 bits (304), Expect = 5e-28
 Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
           L   +++ LC +++EI   +    E+  P+ + GD HGQ                     
Sbjct: 30  LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 90  -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 144
            GDY+DRG  S+E + LLLA K+ Y E   +L  NHE   I ++Y  Y+EC R++     
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149

Query: 145 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 192
                        A  D ++FC HGGLSP + ++  IR +     +P +G + DLL+SDP
Sbjct: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209

Query: 193 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
           D         D     TF         H   L L+ RAHQ+V  G+ +     +V +FS 
Sbjct: 210 DKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269

Query: 236 PNYC 239
           PNYC
Sbjct: 270 PNYC 273


>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
           1 [Homo sapiens]
          Length = 330

 Score =  121 bits (304), Expect = 5e-28
 Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
           L   +++ LC +++EI   +    E+  P+ + GD HGQ                     
Sbjct: 30  LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 90  -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 144
            GDY+DRG  S+E + LLLA K+ Y E   +L  NHE   I ++Y  Y+EC R++     
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149

Query: 145 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 192
                        A  D ++FC HGGLSP + ++  IR +     +P +G + DLL+SDP
Sbjct: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209

Query: 193 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
           D         D     TF         H   L L+ RAHQ+V  G+ +     +V +FS 
Sbjct: 210 DKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269

Query: 236 PNYC 239
           PNYC
Sbjct: 270 PNYC 273


>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
           1 [Homo sapiens]
          Length = 327

 Score =  118 bits (296), Expect = 4e-27
 Identities = 80/269 (29%), Positives = 117/269 (43%), Gaps = 55/269 (20%)

Query: 26  GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 85
           G   V S    LL     +   +  +   +V+ LC +++EI   +    E+  P+ + GD
Sbjct: 4   GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63

Query: 86  KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 123
            HGQ                      GDY+DRG  S+E + LLLA K+ Y E   +L  N
Sbjct: 64  IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123

Query: 124 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 167
           HE   I ++Y  Y+EC R+                   A  D ++FC HGGLSP + ++ 
Sbjct: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183

Query: 168 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 210
            IR +     +P  G + DLL+SDPD                   D    F +   L L+
Sbjct: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243

Query: 211 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
            RAHQ+V  G+ +     +V +FS PNYC
Sbjct: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272


>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
           [Homo sapiens]
          Length = 327

 Score =  118 bits (296), Expect = 4e-27
 Identities = 80/269 (29%), Positives = 117/269 (43%), Gaps = 55/269 (20%)

Query: 26  GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 85
           G   V S    LL     +   +  +   +V+ LC +++EI   +    E+  P+ + GD
Sbjct: 4   GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63

Query: 86  KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 123
            HGQ                      GDY+DRG  S+E + LLLA K+ Y E   +L  N
Sbjct: 64  IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123

Query: 124 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 167
           HE   I ++Y  Y+EC R+                   A  D ++FC HGGLSP + ++ 
Sbjct: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183

Query: 168 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 210
            IR +     +P  G + DLL+SDPD                   D    F +   L L+
Sbjct: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243

Query: 211 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
            RAHQ+V  G+ +     +V +FS PNYC
Sbjct: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272


>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
           2 [Homo sapiens]
          Length = 286

 Score =  108 bits (271), Expect = 3e-24
 Identities = 65/183 (35%), Positives = 91/183 (49%), Gaps = 33/183 (18%)

Query: 90  GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG----- 144
           GDY+DRG  S+E + LLLA K+ Y E   +L  NHE   I ++Y  Y+EC R++      
Sbjct: 47  GDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWK 106

Query: 145 -----------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD 193
                       A  D ++FC HGGLSP + ++  IR +     +P +G + DLL+SDPD
Sbjct: 107 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPD 166

Query: 194 ---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTP 236
                    D     TF         H   L L+ RAHQ+V  G+ +     +V +FS P
Sbjct: 167 KDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 226

Query: 237 NYC 239
           NYC
Sbjct: 227 NYC 229


>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 3 [Homo sapiens]
          Length = 469

 Score =  107 bits (268), Expect = 8e-24
 Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)

Query: 62  EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
           E   IL +E N  ++  PVTV GD HGQ                      GDY+DRGY+S
Sbjct: 67  EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126

Query: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
           IE V+ L A+K+ Y + + +L  NHE R +T+ +   +EC  K+     D          
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186

Query: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
                  Q  C+HGGLSP ++TL  IR L+  ++ P  GPM D+L+SDP     +  T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246

Query: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
            F H                     + L  + RAH+    G+            +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306

Query: 234 STPNY 238
           S PNY
Sbjct: 307 SAPNY 311


>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 2 [Homo sapiens]
          Length = 511

 Score =  107 bits (268), Expect = 8e-24
 Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)

Query: 62  EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
           E   IL +E N  ++  PVTV GD HGQ                      GDY+DRGY+S
Sbjct: 67  EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126

Query: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
           IE V+ L A+K+ Y + + +L  NHE R +T+ +   +EC  K+     D          
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186

Query: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
                  Q  C+HGGLSP ++TL  IR L+  ++ P  GPM D+L+SDP     +  T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246

Query: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
            F H                     + L  + RAH+    G+            +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306

Query: 234 STPNY 238
           S PNY
Sbjct: 307 SAPNY 311


>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
           isoform 1 [Homo sapiens]
          Length = 521

 Score =  107 bits (268), Expect = 8e-24
 Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)

Query: 62  EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
           E   IL +E N  ++  PVTV GD HGQ                      GDY+DRGY+S
Sbjct: 67  EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126

Query: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
           IE V+ L A+K+ Y + + +L  NHE R +T+ +   +EC  K+     D          
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186

Query: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
                  Q  C+HGGLSP ++TL  IR L+  ++ P  GPM D+L+SDP     +  T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246

Query: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
            F H                     + L  + RAH+    G+            +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306

Query: 234 STPNY 238
           S PNY
Sbjct: 307 SAPNY 311


>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
           c [Homo sapiens]
          Length = 515

 Score =  102 bits (253), Expect = 4e-22
 Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)

Query: 59  LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
           +  E   IL  E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132

Query: 97  YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 145
           Y+SIE V+ L  +K+ Y   + +L  NHE R +T+ +   +EC  K+             
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192

Query: 146 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 196
                A  + Q  C+HGGLSP + TL  IR L+  ++ P  GPM DLL+SDP +      
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252

Query: 197 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
           + E F+H                     + L  + RAH+    G+            +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312

Query: 231 AIFSTPNY 238
            IFS PNY
Sbjct: 313 TIFSAPNY 320


>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
           a [Homo sapiens]
          Length = 525

 Score =  102 bits (253), Expect = 4e-22
 Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)

Query: 59  LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
           +  E   IL  E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132

Query: 97  YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 145
           Y+SIE V+ L  +K+ Y   + +L  NHE R +T+ +   +EC  K+             
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192

Query: 146 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 196
                A  + Q  C+HGGLSP + TL  IR L+  ++ P  GPM DLL+SDP +      
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252

Query: 197 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
           + E F+H                     + L  + RAH+    G+            +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312

Query: 231 AIFSTPNY 238
            IFS PNY
Sbjct: 313 TIFSAPNY 320


>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
           b [Homo sapiens]
          Length = 524

 Score =  102 bits (253), Expect = 4e-22
 Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)

Query: 59  LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
           +  E   IL  E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132

Query: 97  YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 145
           Y+SIE V+ L  +K+ Y   + +L  NHE R +T+ +   +EC  K+             
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192

Query: 146 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 196
                A  + Q  C+HGGLSP + TL  IR L+  ++ P  GPM DLL+SDP +      
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252

Query: 197 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
           + E F+H                     + L  + RAH+    G+            +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312

Query: 231 AIFSTPNY 238
            IFS PNY
Sbjct: 313 TIFSAPNY 320


>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
           sapiens]
          Length = 512

 Score = 98.2 bits (243), Expect = 6e-21
 Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 68/248 (27%)

Query: 59  LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
           +  +   IL +E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 60  IINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRG 119

Query: 97  YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG------ 150
           Y+SIE V+ L ++K+++ + + +L  NHE R +T  +   +EC  K+     D       
Sbjct: 120 YFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFD 179

Query: 151 ----------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP-DDHDTPE 199
                     Q  C+HGG+SP + +L  IR L+   + P  GP+ DLL+SDP +D+   +
Sbjct: 180 CLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEK 239

Query: 200 TFNH-----------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
           T  H                        + L  + RAH+    G+            +++
Sbjct: 240 TLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLI 299

Query: 231 AIFSTPNY 238
            IFS PNY
Sbjct: 300 TIFSAPNY 307


>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
          Length = 499

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 65/242 (26%), Positives = 100/242 (41%), Gaps = 60/242 (24%)

Query: 62  EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
           + KE+L++ S   E        +TV GD HGQ                       GD++D
Sbjct: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274

Query: 95  RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGD----- 149
           RG +S+E+++ L   K+ Y +   +L  NHE+  + Q+Y    E   K+     +     
Sbjct: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334

Query: 150 -----------GQLFCLHGGL-SPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDH-- 195
                      G++  +HGGL S    TL  IR +   ++ P  GPM DLL+SDP     
Sbjct: 335 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG 394

Query: 196 --------------DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYH 241
                         D  + F   + L  + R+H++   G+   H    V +FS PNYC  
Sbjct: 395 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ 454

Query: 242 CG 243
            G
Sbjct: 455 MG 456


>gi|23312374 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1b [Homo sapiens]
          Length = 625

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 62/256 (24%), Positives = 96/256 (37%), Gaps = 80/256 (31%)

Query: 62  EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
           E K++L +  N   +       VT+ GD HG+                       GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204

Query: 95  RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HGN------ 145
           RG  SIEI+M+L    + Y   + +   NHE   +   Y   +E L K   HG       
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264

Query: 146 ----------ANGDGQLFCLHGGLSPSVDT--LHHIRTLNCLQKI---PHE--------- 181
                        D ++  +HGG+S + D   LH +   N ++ +   P E         
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVER-NKMKSVLIPPTETNRDHDTDS 323

Query: 182 --GPMGDLLYSDPDDH-----------------DTPETFNHASGLRLVSRAHQLVMVGHN 222
               + D+L+SDP                    D      +   L+++ R+H+    G+ 
Sbjct: 324 KHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYE 383

Query: 223 WCHDWNVVAIFSTPNY 238
            CHD  VV IFS  NY
Sbjct: 384 ICHDGKVVTIFSASNY 399


>gi|23312378 protein phosphatase with EF hand calcium-binding domain
           1 isoform 3 [Homo sapiens]
          Length = 591

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 66/232 (28%)

Query: 62  EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
           E K++L +  N   +       VT+ GD HG+                       GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204

Query: 95  RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
           RG  SIEI+M+L    + Y   + +   NHE   +   Y   +E L K   HG       
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264

Query: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD-- 193
                        D ++  +HGG+S + D       LN L ++     M  +L    +  
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTD-------LNLLHRV-ERNKMKSVLIPPTETN 316

Query: 194 -DHDTPETFNHASGLRLVSRAHQLVMVG-----HNWCHDW-NVVAIFSTPNY 238
            DHDT    N      +   AH  +        H   H+W  VV IFS  NY
Sbjct: 317 RDHDTDSKHNKVG---VTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNY 365


>gi|23312380 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1 [Homo sapiens]
          Length = 653

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 63/283 (22%), Positives = 95/283 (33%), Gaps = 106/283 (37%)

Query: 62  EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
           E K++L +  N   +       VT+ GD HG+                       GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204

Query: 95  RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
           RG  SIEI+M+L    + Y   + +   NHE   +   Y   +E L K   HG       
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264

Query: 145 ---------NANGDGQLFCLHGGLSPSVD--TLHHIR----------------------- 170
                        D ++  +HGG+S + D   LH +                        
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324

Query: 171 ------TLNCLQKIPHEG------------PMGDLLYSDPDDH----------------- 195
                 T N   +I   G             + D+L+SDP                    
Sbjct: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384

Query: 196 DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 238
           D      +   L+++ R+H+    G+  CHD  VV IFS  NY
Sbjct: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 427


>gi|23312386 serine/threonine protein phosphatase with EF-hand
           motifs 2 [Homo sapiens]
          Length = 753

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 43/160 (26%), Positives = 62/160 (38%), Gaps = 46/160 (28%)

Query: 51  LGSRKVKSLCKEAKEILTEESNAQEVWC----PVTVSGDKHGQ----------------- 89
           L +R V +L  E K+ L +  N   V       +TV GD HGQ                 
Sbjct: 141 LHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPE 200

Query: 90  ------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK- 142
                 GD++DRG  S+EI+M+L A  + Y +   +   NHE   +   Y   +E + K 
Sbjct: 201 RSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKY 260

Query: 143 --HGN----------------ANGDGQLFCLHGGLSPSVD 164
             HG                    D ++  LHGG+S   D
Sbjct: 261 KVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITD 300



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 11/32 (34%), Positives = 20/32 (62%)

Query: 207 LRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 238
           ++ + R+H+    G+ +CH+  V+ IFS  NY
Sbjct: 481 MQFLIRSHECKPEGYEFCHNRKVLTIFSASNY 512


>gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 525

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 3/45 (6%)

Query: 2   RQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAA 46
           R  ++  G   A +P   P R C G+RGV S    LL +PAP++A
Sbjct: 377 RSELAPPGAQDALSPD--PERPCPGTRGVRSGREGLL-SPAPRSA 418


>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
           sapiens]
          Length = 800

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 3/45 (6%)

Query: 2   RQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAA 46
           R  ++  G   A +P   P R C G+RGV S    LL +PAP++A
Sbjct: 477 RSELAPPGARDALSPD--PERPCPGTRGVRSGREGLL-SPAPRSA 518


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,366,194
Number of Sequences: 37866
Number of extensions: 560927
Number of successful extensions: 2145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2051
Number of HSP's gapped (non-prelim): 57
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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