Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 117168250
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117168250 phospholipase C, epsilon 1 [Homo sapiens]
(2302 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117168250 phospholipase C, epsilon 1 [Homo sapiens] 4628 0.0
gi|195972873 phospholipase C eta 1 isoform c [Homo sapiens] 307 7e-83
gi|195972871 phospholipase C eta 1 isoform a [Homo sapiens] 307 7e-83
gi|57863298 phospholipase C eta 1 isoform b [Homo sapiens] 307 7e-83
gi|78499633 phospholipase C, eta 2 [Homo sapiens] 298 4e-80
gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens] 219 3e-56
gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens] 219 3e-56
gi|33469933 phospholipase C beta 4 isoform a [Homo sapiens] 204 1e-51
gi|33469939 phospholipase C beta 4 isoform b [Homo sapiens] 204 1e-51
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] 193 1e-48
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] 193 1e-48
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 187 8e-47
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso... 187 8e-47
gi|117320537 phospholipase C, gamma 2 [Homo sapiens] 187 8e-47
gi|19115964 phospholipase C delta 3 [Homo sapiens] 182 3e-45
gi|14249340 phospholipase C, delta 4 [Homo sapiens] 177 8e-44
gi|95147333 phospholipase C, beta 2 [Homo sapiens] 177 8e-44
gi|25188201 phospholipase C, zeta 1 [Homo sapiens] 176 3e-43
gi|221219000 phospholipase C-like 2 isoform 1 [Homo sapiens] 170 1e-41
gi|163644311 phospholipase C-like 2 isoform 2 [Homo sapiens] 170 1e-41
gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens] 162 3e-39
gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens] 162 3e-39
gi|11386139 phospholipase C beta 3 [Homo sapiens] 160 2e-38
gi|7662070 Ral GEF with PH domain and SH3 binding motif 1 [Homo ... 63 3e-09
gi|32441283 Ral GEF with PH domain and SH3 binding motif 2 [Homo... 60 3e-08
gi|15529996 son of sevenless homolog 1 [Homo sapiens] 54 1e-06
gi|213385270 RAS guanyl releasing protein 3 (calcium and DAG-reg... 54 2e-06
gi|24762239 RAS guanyl releasing protein 3 (calcium and DAG-regu... 54 2e-06
gi|7662334 RAS guanyl releasing protein 3 (calcium and DAG-regul... 54 2e-06
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 49 4e-05
>gi|117168250 phospholipase C, epsilon 1 [Homo sapiens]
Length = 2302
Score = 4628 bits (12004), Expect = 0.0
Identities = 2302/2302 (100%), Positives = 2302/2302 (100%)
Query: 1 MTSEEMTASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRRSGETSHTISQLNKL 60
MTSEEMTASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRRSGETSHTISQLNKL
Sbjct: 1 MTSEEMTASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRRSGETSHTISQLNKL 60
Query: 61 KEEPSGSNLPKILSIAREKIVSDENSNEKCWEKIMPDSAKNLNINCNNILRNHQHGLPQR 120
KEEPSGSNLPKILSIAREKIVSDENSNEKCWEKIMPDSAKNLNINCNNILRNHQHGLPQR
Sbjct: 61 KEEPSGSNLPKILSIAREKIVSDENSNEKCWEKIMPDSAKNLNINCNNILRNHQHGLPQR 120
Query: 121 QFYEMYNSVAEEDLCLETGIPSPLERKVFPGIQLELDRPSMGISPLGNQSVIIETGRAHP 180
QFYEMYNSVAEEDLCLETGIPSPLERKVFPGIQLELDRPSMGISPLGNQSVIIETGRAHP
Sbjct: 121 QFYEMYNSVAEEDLCLETGIPSPLERKVFPGIQLELDRPSMGISPLGNQSVIIETGRAHP 180
Query: 181 DSRRAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKKNYVAYTCKLMEL 240
DSRRAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKKNYVAYTCKLMEL
Sbjct: 181 DSRRAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKKNYVAYTCKLMEL 240
Query: 241 AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCEKVDMVYSGDSFCRKDFTDSQAAKTFLSHF 300
AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCEKVDMVYSGDSFCRKDFTDSQAAKTFLSHF
Sbjct: 241 AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCEKVDMVYSGDSFCRKDFTDSQAAKTFLSHF 300
Query: 301 EDFPDNCDDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTA 360
EDFPDNCDDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTA
Sbjct: 301 EDFPDNCDDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTA 360
Query: 361 WSYIDQKRNGPLLPCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETENTVGSLL 420
WSYIDQKRNGPLLPCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETENTVGSLL
Sbjct: 361 WSYIDQKRNGPLLPCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETENTVGSLL 420
Query: 421 HFLTKLPASETAHGRISVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR 480
HFLTKLPASETAHGRISVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
Sbjct: 421 HFLTKLPASETAHGRISVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR 480
Query: 481 SGLLSTFGGSTGRMMLKERQPGPSVANSNALPSSSAGISKELIDLQPLIQFPEEVASILM 540
SGLLSTFGGSTGRMMLKERQPGPSVANSNALPSSSAGISKELIDLQPLIQFPEEVASILM
Sbjct: 481 SGLLSTFGGSTGRMMLKERQPGPSVANSNALPSSSAGISKELIDLQPLIQFPEEVASILM 540
Query: 541 EQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALEDLVMR 600
EQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALEDLVMR
Sbjct: 541 EQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALEDLVMR 600
Query: 601 FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW 660
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
Sbjct: 601 FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW 660
Query: 661 QFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA 720
QFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
Sbjct: 661 QFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA 720
Query: 721 SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRS 780
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRS
Sbjct: 721 SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRS 780
Query: 781 LETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFD 840
LETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFD
Sbjct: 781 LETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFD 840
Query: 841 HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTAS 900
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTAS
Sbjct: 841 HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTAS 900
Query: 901 PASSKAKLGVLNNTAEPGKFPLLGNAGLSSLTEGVLDLFAVKAVYMGHPGIDIHTVCVQN 960
PASSKAKLGVLNNTAEPGKFPLLGNAGLSSLTEGVLDLFAVKAVYMGHPGIDIHTVCVQN
Sbjct: 901 PASSKAKLGVLNNTAEPGKFPLLGNAGLSSLTEGVLDLFAVKAVYMGHPGIDIHTVCVQN 960
Query: 961 KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ 1020
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
Sbjct: 961 KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ 1020
Query: 1021 QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPNMQRNNTLG 1080
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPNMQRNNTLG
Sbjct: 1021 QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPNMQRNNTLG 1080
Query: 1081 ISTTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNAIANP 1140
ISTTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNAIANP
Sbjct: 1081 ISTTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNAIANP 1140
Query: 1141 PNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM 1200
PNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM
Sbjct: 1141 PNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM 1200
Query: 1201 KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTI 1260
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTI
Sbjct: 1201 KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTI 1260
Query: 1261 DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLG 1320
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLG
Sbjct: 1261 DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLG 1320
Query: 1321 IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENF 1380
IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENF
Sbjct: 1321 IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENF 1380
Query: 1381 ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC 1440
ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
Sbjct: 1381 ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC 1440
Query: 1441 WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI 1500
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
Sbjct: 1441 WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI 1500
Query: 1501 FKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLA 1560
FKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLA
Sbjct: 1501 FKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLA 1560
Query: 1561 SMQVQAYNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN 1620
SMQVQAYNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
Sbjct: 1561 SMQVQAYNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN 1620
Query: 1621 EEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGL 1680
EEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGL
Sbjct: 1621 EEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGL 1680
Query: 1681 STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLN 1740
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLN
Sbjct: 1681 STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLN 1740
Query: 1741 PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPN 1800
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPN
Sbjct: 1741 PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPN 1800
Query: 1801 PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE 1860
PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
Sbjct: 1801 PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE 1860
Query: 1861 RDLDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW 1920
RDLDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
Sbjct: 1861 RDLDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW 1920
Query: 1921 NEQFLFHVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS 1980
NEQFLFHVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
Sbjct: 1921 NEQFLFHVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS 1980
Query: 1981 LFINSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQ 2040
LFINSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQ
Sbjct: 1981 LFINSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQ 2040
Query: 2041 LLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPE 2100
LLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPE
Sbjct: 2041 LLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPE 2100
Query: 2101 EGYMGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVST 2160
EGYMGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVST
Sbjct: 2101 EGYMGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVST 2160
Query: 2161 AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQ 2220
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQ
Sbjct: 2161 AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQ 2220
Query: 2221 AQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSES 2280
AQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSES
Sbjct: 2221 AQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSES 2280
Query: 2281 IQTKEEKPVGGLSSSDTMDYRQ 2302
IQTKEEKPVGGLSSSDTMDYRQ
Sbjct: 2281 IQTKEEKPVGGLSSSDTMDYRQ 2302
>gi|195972873 phospholipase C eta 1 isoform c [Homo sapiens]
Length = 1002
Score = 307 bits (787), Expect = 7e-83
Identities = 222/667 (33%), Positives = 333/667 (49%), Gaps = 80/667 (11%)
Query: 1328 QLNDFL-VNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDE 1386
+L FL V + + T D L II+KFE S + ++ EGF F M N
Sbjct: 235 ELAQFLKVEQKMNNVTTDYCLDIIKKFEVSEENKVKNVLGIEGFTNF-MRSPACDIFNPL 293
Query: 1387 SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG 1446
E +++ PL YYI SSHNTYLTG QL +S V++Y++VL +GCR VE+DCWDG DG
Sbjct: 294 HHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDG 353
Query: 1447 MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG 1506
P+++HG+TLT+KI F++VVE I++ AF+ ++ P+I+SIENHCS+ QQRK+A+ K +FG
Sbjct: 354 EPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFG 413
Query: 1507 EKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQA 1566
+KL L D + LPSP L+ K+L+K KKL H
Sbjct: 414 DKL---DLSSVDTGECKQLPSPQSLKGKILVKGKKLPYHL-------------------- 450
Query: 1567 YNGGNANPRPANNEEEEDE-EDEYDYDYESLSDDNILEDRPENKSCNDKLQFE---YNEE 1622
G +A ++E+ DE EDE C KL + +
Sbjct: 451 --GDDAEEGEVSDEDSADEIEDE----------------------CKFKLHYSNGTTEHQ 486
Query: 1623 IPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLST 1682
+ I+K S + ++ D E + F + K + + L+ + VK G +
Sbjct: 487 VESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHE---GLNAHLKQSPDVKESGKKS 543
Query: 1683 LNAS-GSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIR----QTWEESSS 1737
S ++ GK +K+ KS + S K G+ G R + E S
Sbjct: 544 HGRSLMTNFGKHKKTTKSRSKSYSTDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSD 603
Query: 1738 PLNPTTSLSA--IIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRID 1795
+ T S++A I+ ++ S +E A ++ ++ S++ + QL R YP+A RID
Sbjct: 604 LVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRID 663
Query: 1796 SSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQK 1855
SSN NPL +W G QLVALNYQ++ + LN A F+ANG CGYVLKP +
Sbjct: 664 SSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGT------ 717
Query: 1856 FSPLERD-LDSMDPAVYSLTIVSGQNV-CPSNSMG-------SPCIEVDVLGMPLDSCHF 1906
F+P D L + L ++SGQ + P +SM P +EV+++G+P+D C
Sbjct: 718 FNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKD 777
Query: 1907 RTKPIHRNTLNPMWNEQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYR 1964
+T+ + N NP+W E F VH ++ +RF V +++ QR + +L GYR
Sbjct: 778 QTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYR 837
Query: 1965 HLQLRNL 1971
H+ L L
Sbjct: 838 HVYLEGL 844
>gi|195972871 phospholipase C eta 1 isoform a [Homo sapiens]
Length = 1693
Score = 307 bits (787), Expect = 7e-83
Identities = 222/667 (33%), Positives = 333/667 (49%), Gaps = 80/667 (11%)
Query: 1328 QLNDFL-VNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDE 1386
+L FL V + + T D L II+KFE S + ++ EGF F M N
Sbjct: 235 ELAQFLKVEQKMNNVTTDYCLDIIKKFEVSEENKVKNVLGIEGFTNF-MRSPACDIFNPL 293
Query: 1387 SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG 1446
E +++ PL YYI SSHNTYLTG QL +S V++Y++VL +GCR VE+DCWDG DG
Sbjct: 294 HHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDG 353
Query: 1447 MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG 1506
P+++HG+TLT+KI F++VVE I++ AF+ ++ P+I+SIENHCS+ QQRK+A+ K +FG
Sbjct: 354 EPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFG 413
Query: 1507 EKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQA 1566
+KL L D + LPSP L+ K+L+K KKL H
Sbjct: 414 DKL---DLSSVDTGECKQLPSPQSLKGKILVKGKKLPYHL-------------------- 450
Query: 1567 YNGGNANPRPANNEEEEDE-EDEYDYDYESLSDDNILEDRPENKSCNDKLQFE---YNEE 1622
G +A ++E+ DE EDE C KL + +
Sbjct: 451 --GDDAEEGEVSDEDSADEIEDE----------------------CKFKLHYSNGTTEHQ 486
Query: 1623 IPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLST 1682
+ I+K S + ++ D E + F + K + + L+ + VK G +
Sbjct: 487 VESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHE---GLNAHLKQSPDVKESGKKS 543
Query: 1683 LNAS-GSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIR----QTWEESSS 1737
S ++ GK +K+ KS + S K G+ G R + E S
Sbjct: 544 HGRSLMTNFGKHKKTTKSRSKSYSTDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSD 603
Query: 1738 PLNPTTSLSA--IIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRID 1795
+ T S++A I+ ++ S +E A ++ ++ S++ + QL R YP+A RID
Sbjct: 604 LVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRID 663
Query: 1796 SSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQK 1855
SSN NPL +W G QLVALNYQ++ + LN A F+ANG CGYVLKP +
Sbjct: 664 SSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGT------ 717
Query: 1856 FSPLERD-LDSMDPAVYSLTIVSGQNV-CPSNSMG-------SPCIEVDVLGMPLDSCHF 1906
F+P D L + L ++SGQ + P +SM P +EV+++G+P+D C
Sbjct: 718 FNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKD 777
Query: 1907 RTKPIHRNTLNPMWNEQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYR 1964
+T+ + N NP+W E F VH ++ +RF V +++ QR + +L GYR
Sbjct: 778 QTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYR 837
Query: 1965 HLQLRNL 1971
H+ L L
Sbjct: 838 HVYLEGL 844
>gi|57863298 phospholipase C eta 1 isoform b [Homo sapiens]
Length = 1655
Score = 307 bits (787), Expect = 7e-83
Identities = 222/667 (33%), Positives = 333/667 (49%), Gaps = 80/667 (11%)
Query: 1328 QLNDFL-VNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDE 1386
+L FL V + + T D L II+KFE S + ++ EGF F M N
Sbjct: 217 ELAQFLKVEQKMNNVTTDYCLDIIKKFEVSEENKVKNVLGIEGFTNF-MRSPACDIFNPL 275
Query: 1387 SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG 1446
E +++ PL YYI SSHNTYLTG QL +S V++Y++VL +GCR VE+DCWDG DG
Sbjct: 276 HHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDG 335
Query: 1447 MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG 1506
P+++HG+TLT+KI F++VVE I++ AF+ ++ P+I+SIENHCS+ QQRK+A+ K +FG
Sbjct: 336 EPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFG 395
Query: 1507 EKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQA 1566
+KL L D + LPSP L+ K+L+K KKL H
Sbjct: 396 DKL---DLSSVDTGECKQLPSPQSLKGKILVKGKKLPYHL-------------------- 432
Query: 1567 YNGGNANPRPANNEEEEDE-EDEYDYDYESLSDDNILEDRPENKSCNDKLQFE---YNEE 1622
G +A ++E+ DE EDE C KL + +
Sbjct: 433 --GDDAEEGEVSDEDSADEIEDE----------------------CKFKLHYSNGTTEHQ 468
Query: 1623 IPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLST 1682
+ I+K S + ++ D E + F + K + + L+ + VK G +
Sbjct: 469 VESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHE---GLNAHLKQSPDVKESGKKS 525
Query: 1683 LNAS-GSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIR----QTWEESSS 1737
S ++ GK +K+ KS + S K G+ G R + E S
Sbjct: 526 HGRSLMTNFGKHKKTTKSRSKSYSTDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSD 585
Query: 1738 PLNPTTSLSA--IIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRID 1795
+ T S++A I+ ++ S +E A ++ ++ S++ + QL R YP+A RID
Sbjct: 586 LVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRID 645
Query: 1796 SSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQK 1855
SSN NPL +W G QLVALNYQ++ + LN A F+ANG CGYVLKP +
Sbjct: 646 SSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGT------ 699
Query: 1856 FSPLERD-LDSMDPAVYSLTIVSGQNV-CPSNSMG-------SPCIEVDVLGMPLDSCHF 1906
F+P D L + L ++SGQ + P +SM P +EV+++G+P+D C
Sbjct: 700 FNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKD 759
Query: 1907 RTKPIHRNTLNPMWNEQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYR 1964
+T+ + N NP+W E F VH ++ +RF V +++ QR + +L GYR
Sbjct: 760 QTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYR 819
Query: 1965 HLQLRNL 1971
H+ L L
Sbjct: 820 HVYLEGL 826
>gi|78499633 phospholipase C, eta 2 [Homo sapiens]
Length = 1416
Score = 298 bits (763), Expect = 4e-80
Identities = 208/668 (31%), Positives = 324/668 (48%), Gaps = 91/668 (13%)
Query: 1342 TYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYY 1401
T + II++FEP +GL+ +GF + N E +++ PLS+Y
Sbjct: 277 TLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIF-NPEHHHVHQDMTQPLSHY 335
Query: 1402 YIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIP 1461
+I SSHNTYL G QL +S V++Y+ VL GCR VE+DCWDG DG PI++HG+TLT+KI
Sbjct: 336 FITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKIL 395
Query: 1462 FKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSD 1521
FK+V+E I++ AFI ++ P+I+SIENHCS+ QQ+KMA+ + G+KL L D
Sbjct: 396 FKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKL---DLSSVSSED 452
Query: 1522 DPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPANNEE 1581
LPSP L+ K+L+K KKL A+ + + A +
Sbjct: 453 ATTLPSPQMLKGKILVKGKKLPAN------ISEDAEE-------------------GEVS 487
Query: 1582 EEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRIKKADNSACN----K 1637
+ED DE D D + L+ D + + KL E + + +N + +
Sbjct: 488 DEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVSTLSPS 547
Query: 1638 GKV-------YDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASGSSR 1690
GK+ D+E GE+ +++ R + S +
Sbjct: 548 GKLGRKSKAEEDVESGED--AGASRRNGRLVVGSFS-------------------RRKKK 586
Query: 1691 GKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTTSLSA--- 1747
G + K S+ + G+ SPG ++ G + + + S + T S++
Sbjct: 587 GSKLKKAASVEEGDEGQDSPG-----GQSRGATRQKKTMKLSRALSDLVKYTKSVATHDI 641
Query: 1748 IIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLH 1807
+ + +SS +E A ++ ++ + + QL R YP++ R+DSSN NP FW
Sbjct: 642 EMEAASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNA 701
Query: 1808 GIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD-LDSM 1866
G Q+VALNYQ++ L LN A F ANGGCGYVLKP C F+P D L
Sbjct: 702 GCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKP------GCMCQGVFNPNSEDPLPGQ 755
Query: 1867 DPAVYSLTIVSGQNV-CPSNSM-------GSPCIEVDVLGMPLDSCHFRTKPIHRNTLNP 1918
L I+SGQ + P +SM P +EV+++G+P+D +T+ + N NP
Sbjct: 756 LKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNP 815
Query: 1919 MWNEQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVL 1976
W E +F VH ++ +RF V +++ QR + ++ GYRH+ L E +
Sbjct: 816 TWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYL-----EGM 870
Query: 1977 EISSLFIN 1984
E +S+F++
Sbjct: 871 EEASIFVH 878
>gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens]
Length = 756
Score = 219 bits (557), Expect = 3e-56
Identities = 195/668 (29%), Positives = 288/668 (43%), Gaps = 161/668 (24%)
Query: 1328 QLNDFLVNCQGEHCTYDEI-LSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDE 1386
QL FL + Q E + LS+I+++EPS + Q M+ +GF +L+ + A
Sbjct: 232 QLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAH 291
Query: 1387 SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG 1446
+ +++ PLS+Y + SSHNTYL QL G SS E Y + L +GCR +ELDCWDG +
Sbjct: 292 RRV-YQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQ 350
Query: 1447 MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG 1506
PIIYHG+T T+KI F +V+ AI AF S P+I+S+ENHC+L QQR MA + G
Sbjct: 351 EPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILG 410
Query: 1507 EKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQA 1566
L+ + L S LPSP+QL+ K+LLK KKL P
Sbjct: 411 PMLLNRPLDGVTNS----LPSPEQLKGKILLKGKKLGGLLPP------------------ 448
Query: 1567 YNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKR 1626
GG P A +EDE E +D + R ++K DKL
Sbjct: 449 --GGEGGPE-ATVVSDEDEAAE--------MEDEAVRSRVQHKPKEDKL----------- 486
Query: 1627 IKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNAS 1686
++A ELSD+VIYC++V F G S
Sbjct: 487 ---------------------------------RLAQELSDMVIYCKSVHFGGFS----- 508
Query: 1687 GSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTTSLS 1746
+PG +PG+ +F + + S +R E + +
Sbjct: 509 -----------------SPG--TPGQ--AFYEMASFSENRALRLLQESGNGFVRHNVG-- 545
Query: 1747 AIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWL 1806
H+S + + YS + CQ++ ++ P P M
Sbjct: 546 ---------HLSRIYPAGWRTDSSNYSPVEMWNGGCQIV-------ALNFQTPGPEMDVY 589
Query: 1807 HGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSM 1866
G F+ NG CGYVLKP L D N F+P R L +
Sbjct: 590 QG--------------------RFQDNGACGYVLKPAFLRDPN----GTFNP--RAL-AQ 622
Query: 1867 DP----AVYSLTIVSGQNVCP----SNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNP 1918
P ++ ++SGQ + NS+ P + V++ G+ D +T I N NP
Sbjct: 623 GPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNP 682
Query: 1919 MWNEQFLFHVHFEDLVFLRFAVVENNSSA---VTAQRIIPLKALKRGYRHLQLRNLHNEV 1975
W+ +F F V DL +RF V + ++S+ Q IPL +LK+GYRH+ L + + +
Sbjct: 683 WWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLMSKNGDQ 742
Query: 1976 LEISSLFI 1983
++LF+
Sbjct: 743 HPSATLFV 750
>gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens]
Length = 777
Score = 219 bits (557), Expect = 3e-56
Identities = 195/668 (29%), Positives = 288/668 (43%), Gaps = 161/668 (24%)
Query: 1328 QLNDFLVNCQGEHCTYDEI-LSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDE 1386
QL FL + Q E + LS+I+++EPS + Q M+ +GF +L+ + A
Sbjct: 253 QLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAH 312
Query: 1387 SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG 1446
+ +++ PLS+Y + SSHNTYL QL G SS E Y + L +GCR +ELDCWDG +
Sbjct: 313 RRV-YQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQ 371
Query: 1447 MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG 1506
PIIYHG+T T+KI F +V+ AI AF S P+I+S+ENHC+L QQR MA + G
Sbjct: 372 EPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILG 431
Query: 1507 EKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQA 1566
L+ + L S LPSP+QL+ K+LLK KKL P
Sbjct: 432 PMLLNRPLDGVTNS----LPSPEQLKGKILLKGKKLGGLLPP------------------ 469
Query: 1567 YNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKR 1626
GG P A +EDE E +D + R ++K DKL
Sbjct: 470 --GGEGGPE-ATVVSDEDEAAE--------MEDEAVRSRVQHKPKEDKL----------- 507
Query: 1627 IKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNAS 1686
++A ELSD+VIYC++V F G S
Sbjct: 508 ---------------------------------RLAQELSDMVIYCKSVHFGGFS----- 529
Query: 1687 GSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTTSLS 1746
+PG +PG+ +F + + S +R E + +
Sbjct: 530 -----------------SPG--TPGQ--AFYEMASFSENRALRLLQESGNGFVRHNVG-- 566
Query: 1747 AIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWL 1806
H+S + + YS + CQ++ ++ P P M
Sbjct: 567 ---------HLSRIYPAGWRTDSSNYSPVEMWNGGCQIV-------ALNFQTPGPEMDVY 610
Query: 1807 HGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSM 1866
G F+ NG CGYVLKP L D N F+P R L +
Sbjct: 611 QG--------------------RFQDNGACGYVLKPAFLRDPN----GTFNP--RAL-AQ 643
Query: 1867 DP----AVYSLTIVSGQNVCP----SNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNP 1918
P ++ ++SGQ + NS+ P + V++ G+ D +T I N NP
Sbjct: 644 GPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNP 703
Query: 1919 MWNEQFLFHVHFEDLVFLRFAVVENNSSA---VTAQRIIPLKALKRGYRHLQLRNLHNEV 1975
W+ +F F V DL +RF V + ++S+ Q IPL +LK+GYRH+ L + + +
Sbjct: 704 WWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLMSKNGDQ 763
Query: 1976 LEISSLFI 1983
++LF+
Sbjct: 764 HPSATLFV 771
>gi|33469933 phospholipase C beta 4 isoform a [Homo sapiens]
Length = 1194
Score = 204 bits (518), Expect = 1e-51
Identities = 129/337 (38%), Positives = 188/337 (55%), Gaps = 30/337 (8%)
Query: 1347 LSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYIESS 1406
+ II+ +EP + +GL+S +GF R+LM EN D E +E+ PL++Y+I SS
Sbjct: 269 MQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRL-ELYQEMDHPLAHYFISSS 327
Query: 1407 HNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG--DDGMPIIYHGHTLTTKIPFKE 1464
HNTYLTG Q G+SSVE+Y QVLL GCR VELDCWDG +D PII HG + T I FK+
Sbjct: 328 HNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKD 387
Query: 1465 VVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPM 1524
V++AI +AF+ S+ P+I+S ENHCS QQ KM++ + +FG+ L+ + L
Sbjct: 388 VIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRA 447
Query: 1525 LPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPANNEEEED 1584
LPSP+ L++K+L+KNK+LK ++ K++ L SM + AN +NEEE +
Sbjct: 448 LPSPNDLKRKILIKNKRLKP-----EVEKKQLEALRSMMEAGESASPANILEDDNEEEIE 502
Query: 1585 EEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDME 1644
D+ + E PE K N+ + K+A ++ KG V +
Sbjct: 503 SADQEE------------EAHPEFKFGNELSADDLGH------KEAVANSVKKGLVTVED 544
Query: 1645 LGEEFYLDQNK--KESRQIAPELSDLVIYCQAVKFPG 1679
E+ ++ K + I P LS ++ Y Q VKF G
Sbjct: 545 --EQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQG 579
Score = 154 bits (388), Expect = 1e-36
Identities = 91/235 (38%), Positives = 137/235 (58%), Gaps = 12/235 (5%)
Query: 1755 YHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVAL 1814
Y++SS NE+ + ++ + + Q+ R YP R+DSSN P +FW G Q+V+L
Sbjct: 590 YNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSL 649
Query: 1815 NYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL-ERDLDSMDPAVYSL 1873
NYQT DL + LN FE NG CGY+LKP + + + F P E +D + A S+
Sbjct: 650 NYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPD----RTFDPFSETPVDGVIAATCSV 705
Query: 1874 TIVSGQNVCPSNSMGSPCIEVDVLGMPLDSC--HFRTKPIHRNTLNPMWNEQ-FLFH-VH 1929
++SGQ + S+ +EVD+ G+P D+ FRT+ + N LNP++NE+ F+F V
Sbjct: 706 QVISGQFL--SDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVI 763
Query: 1930 FEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984
DL LR AV ++N+ + QRI+PL L+ GYRH+ LRN N+ L + ++F N
Sbjct: 764 LPDLAVLRIAVYDDNNKLI-GQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCN 817
>gi|33469939 phospholipase C beta 4 isoform b [Homo sapiens]
Length = 1175
Score = 204 bits (518), Expect = 1e-51
Identities = 129/337 (38%), Positives = 188/337 (55%), Gaps = 30/337 (8%)
Query: 1347 LSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYIESS 1406
+ II+ +EP + +GL+S +GF R+LM EN D E +E+ PL++Y+I SS
Sbjct: 269 MQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRL-ELYQEMDHPLAHYFISSS 327
Query: 1407 HNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG--DDGMPIIYHGHTLTTKIPFKE 1464
HNTYLTG Q G+SSVE+Y QVLL GCR VELDCWDG +D PII HG + T I FK+
Sbjct: 328 HNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKD 387
Query: 1465 VVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPM 1524
V++AI +AF+ S+ P+I+S ENHCS QQ KM++ + +FG+ L+ + L
Sbjct: 388 VIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRA 447
Query: 1525 LPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPANNEEEED 1584
LPSP+ L++K+L+KNK+LK ++ K++ L SM + AN +NEEE +
Sbjct: 448 LPSPNDLKRKILIKNKRLKP-----EVEKKQLEALRSMMEAGESASPANILEDDNEEEIE 502
Query: 1585 EEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDME 1644
D+ + E PE K N+ + K+A ++ KG V +
Sbjct: 503 SADQEE------------EAHPEFKFGNELSADDLGH------KEAVANSVKKGLVTVED 544
Query: 1645 LGEEFYLDQNK--KESRQIAPELSDLVIYCQAVKFPG 1679
E+ ++ K + I P LS ++ Y Q VKF G
Sbjct: 545 --EQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQG 579
Score = 154 bits (388), Expect = 1e-36
Identities = 91/235 (38%), Positives = 137/235 (58%), Gaps = 12/235 (5%)
Query: 1755 YHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVAL 1814
Y++SS NE+ + ++ + + Q+ R YP R+DSSN P +FW G Q+V+L
Sbjct: 590 YNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSL 649
Query: 1815 NYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL-ERDLDSMDPAVYSL 1873
NYQT DL + LN FE NG CGY+LKP + + + F P E +D + A S+
Sbjct: 650 NYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPD----RTFDPFSETPVDGVIAATCSV 705
Query: 1874 TIVSGQNVCPSNSMGSPCIEVDVLGMPLDSC--HFRTKPIHRNTLNPMWNEQ-FLFH-VH 1929
++SGQ + S+ +EVD+ G+P D+ FRT+ + N LNP++NE+ F+F V
Sbjct: 706 QVISGQFL--SDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVI 763
Query: 1930 FEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984
DL LR AV ++N+ + QRI+PL L+ GYRH+ LRN N+ L + ++F N
Sbjct: 764 LPDLAVLRIAVYDDNNKLI-GQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCN 817
>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
Length = 1291
Score = 193 bits (491), Expect = 1e-48
Identities = 117/307 (38%), Positives = 162/307 (52%), Gaps = 14/307 (4%)
Query: 1324 VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPS-----ISMCHQGLMSFEGFARFLMDKE 1378
V + + FL++ QGE D + +Q+F S + + + F FL KE
Sbjct: 249 VSLPEFQQFLLDYQGELWAVDRLQ--VQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKE 306
Query: 1379 NFASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVEL 1438
N + + PLS+Y+I SSHNTYLTG Q ESS+E Y++ L GCR +EL
Sbjct: 307 NSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIEL 366
Query: 1439 DCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMA 1498
DCWDG DGMP+IYHGHTLTTKI F +V+ I AF+ S+ P+I+SIE+HCS+ QQR MA
Sbjct: 367 DCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMA 426
Query: 1499 EIFKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQ 1558
+ FK V G+ L+TK + S D LPSP+QL++K+L+K+KKL ++ +
Sbjct: 427 QYFKKVLGDTLLTK---PVEISADG-LPSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYS 482
Query: 1559 LASMQVQAYNGGNANPRPANNEEEEDE---EDEYDYDYESLSDDNILEDRPENKSCNDKL 1615
+ NG P N+E Y E S D ED E K +
Sbjct: 483 ENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSST 542
Query: 1616 QFEYNEE 1622
+ NE+
Sbjct: 543 ELHSNEK 549
Score = 142 bits (357), Expect = 5e-33
Identities = 91/264 (34%), Positives = 137/264 (51%), Gaps = 16/264 (6%)
Query: 1754 CYH-ISSLNENAAKRLCRRYS-QKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQL 1811
CY +SS E A++ + +K Q+ QL R YP R+DSSN +PL W+ G QL
Sbjct: 976 CYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQL 1035
Query: 1812 VALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLER-DLDSMDPAV 1870
VALN+QT D P+ +N A+F CGYVL+P + D + F P ++ L ++P
Sbjct: 1036 VALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRD------EAFDPFDKSSLRGLEPCA 1089
Query: 1871 YSLTIVSGQNVCPSNSMGSPC--IEVDVLGMPLDSCHFRTKPIHRNTLNPMW-NEQFLFH 1927
S+ ++ +++ P N G C +E++V G DS +T+ + N LNP+W + F F
Sbjct: 1090 ISIEVLGARHL-PKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQ 1148
Query: 1928 VHFEDLVFLRFAVVEN---NSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984
+ + FLRF V E + AQ P+K LK GYR + L+N ++E LE++SL I
Sbjct: 1149 ISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIK 1208
Query: 1985 SRRMEENSSGNTMSASSMFNTEER 2008
+S S + ER
Sbjct: 1209 IDIFPAKQENGDLSPFSGTSLRER 1232
>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
Length = 1290
Score = 193 bits (491), Expect = 1e-48
Identities = 117/307 (38%), Positives = 162/307 (52%), Gaps = 14/307 (4%)
Query: 1324 VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPS-----ISMCHQGLMSFEGFARFLMDKE 1378
V + + FL++ QGE D + +Q+F S + + + F FL KE
Sbjct: 249 VSLPEFQQFLLDYQGELWAVDRLQ--VQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKE 306
Query: 1379 NFASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVEL 1438
N + + PLS+Y+I SSHNTYLTG Q ESS+E Y++ L GCR +EL
Sbjct: 307 NSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIEL 366
Query: 1439 DCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMA 1498
DCWDG DGMP+IYHGHTLTTKI F +V+ I AF+ S+ P+I+SIE+HCS+ QQR MA
Sbjct: 367 DCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMA 426
Query: 1499 EIFKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQ 1558
+ FK V G+ L+TK + S D LPSP+QL++K+L+K+KKL ++ +
Sbjct: 427 QYFKKVLGDTLLTK---PVEISADG-LPSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYS 482
Query: 1559 LASMQVQAYNGGNANPRPANNEEEEDE---EDEYDYDYESLSDDNILEDRPENKSCNDKL 1615
+ NG P N+E Y E S D ED E K +
Sbjct: 483 ENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSST 542
Query: 1616 QFEYNEE 1622
+ NE+
Sbjct: 543 ELHSNEK 549
Score = 141 bits (355), Expect = 8e-33
Identities = 87/239 (36%), Positives = 131/239 (54%), Gaps = 16/239 (6%)
Query: 1754 CYH-ISSLNENAAKRLCRRYS-QKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQL 1811
CY +SS E A++ + +K Q+ QL R YP R+DSSN +PL W+ G QL
Sbjct: 976 CYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQL 1035
Query: 1812 VALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLER-DLDSMDPAV 1870
VALN+QT D P+ +N A+F CGYVL+P + D + F P ++ L ++P
Sbjct: 1036 VALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRD------EAFDPFDKSSLRGLEPCA 1089
Query: 1871 YSLTIVSGQNVCPSNSMGSPC--IEVDVLGMPLDSCHFRTKPIHRNTLNPMW-NEQFLFH 1927
S+ ++ +++ P N G C +E++V G DS +T+ + N LNP+W + F F
Sbjct: 1090 ISIEVLGARHL-PKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQ 1148
Query: 1928 VHFEDLVFLRFAVVEN---NSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
+ + FLRF V E + AQ P+K LK GYR + L+N ++E LE++SL I
Sbjct: 1149 ISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLI 1207
>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
a [Homo sapiens]
Length = 1216
Score = 187 bits (476), Expect = 8e-47
Identities = 122/337 (36%), Positives = 190/337 (56%), Gaps = 21/337 (6%)
Query: 1344 DEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYI 1403
+++ +I+K+EP+ S+ +G +S +GF R+L +EN ++ N +++ PLS+Y+I
Sbjct: 269 EQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLN-EDMSQPLSHYFI 327
Query: 1404 ESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG--DDGMPIIYHGHTLTTKIP 1461
SSHNTYLT QL G SSVE+Y QVLL GCR VELDCW G + P+I HG T+TT+I
Sbjct: 328 NSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEIS 387
Query: 1462 FKEVVEAIDRSAFINSDLPIIISIENHCSLP-QQRKMAEIFKTVFGEKLVTKFLFETDFS 1520
FKEV+EAI AF S PI++S ENH P QQ KMAE + +FG+ L+ + L +
Sbjct: 388 FKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLE 447
Query: 1521 DDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPAN-- 1578
LPSP L K+L+KNKK K+H++ K+K + AS Y+ ++ P++
Sbjct: 448 SGVPLPSPMDLMYKILVKNKK-KSHKSSEGSGKKKLSEQAS---NTYSDSSSMFEPSSPG 503
Query: 1579 ----NEEEEDEEDEYDYDYESL------SDDNILEDRPENKSCNDKLQFEYNEEIPKRIK 1628
+ E +D++D+ D S+ S+ E+ + ++FE E KR K
Sbjct: 504 AGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNK 563
Query: 1629 KADNSACNKGK-VYDMELGEEFYLDQNKKESRQIAPE 1664
+ S+ + K + + +++ NK + +I P+
Sbjct: 564 SFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK 600
Score = 128 bits (322), Expect = 6e-29
Identities = 81/236 (34%), Positives = 126/236 (53%), Gaps = 12/236 (5%)
Query: 1753 KCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLV 1812
K + +SS E + + ++ QL R YP TR+DSSN P +FW G Q+V
Sbjct: 563 KSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMV 622
Query: 1813 ALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL-ERDLDSMDPAVY 1871
ALN+QT DL + +N M+E NG GY LKP + + + F P E +D +
Sbjct: 623 ALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPD----KHFDPFTEGIVDGIVANTL 678
Query: 1872 SLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCH--FRTKPIHRNTLNPMWNEQFLF--H 1927
S+ I+SGQ + S+ +EVD+ G+P+D+ F+TK N +NP+W E+ +
Sbjct: 679 SVKIISGQFL--SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKK 736
Query: 1928 VHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
V L LR AV E + RI+P++A++ GY ++ LRN N+ L + ++F+
Sbjct: 737 VVLPTLACLRIAVYEEGGKFI-GHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV 791
>gi|33356544 phosphoinositide-specific phospholipase C beta 1 isoform
b [Homo sapiens]
Length = 1173
Score = 187 bits (476), Expect = 8e-47
Identities = 122/337 (36%), Positives = 190/337 (56%), Gaps = 21/337 (6%)
Query: 1344 DEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYI 1403
+++ +I+K+EP+ S+ +G +S +GF R+L +EN ++ N +++ PLS+Y+I
Sbjct: 269 EQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLN-EDMSQPLSHYFI 327
Query: 1404 ESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG--DDGMPIIYHGHTLTTKIP 1461
SSHNTYLT QL G SSVE+Y QVLL GCR VELDCW G + P+I HG T+TT+I
Sbjct: 328 NSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEIS 387
Query: 1462 FKEVVEAIDRSAFINSDLPIIISIENHCSLP-QQRKMAEIFKTVFGEKLVTKFLFETDFS 1520
FKEV+EAI AF S PI++S ENH P QQ KMAE + +FG+ L+ + L +
Sbjct: 388 FKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLE 447
Query: 1521 DDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPAN-- 1578
LPSP L K+L+KNKK K+H++ K+K + AS Y+ ++ P++
Sbjct: 448 SGVPLPSPMDLMYKILVKNKK-KSHKSSEGSGKKKLSEQAS---NTYSDSSSMFEPSSPG 503
Query: 1579 ----NEEEEDEEDEYDYDYESL------SDDNILEDRPENKSCNDKLQFEYNEEIPKRIK 1628
+ E +D++D+ D S+ S+ E+ + ++FE E KR K
Sbjct: 504 AGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNK 563
Query: 1629 KADNSACNKGK-VYDMELGEEFYLDQNKKESRQIAPE 1664
+ S+ + K + + +++ NK + +I P+
Sbjct: 564 SFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK 600
Score = 128 bits (322), Expect = 6e-29
Identities = 81/236 (34%), Positives = 126/236 (53%), Gaps = 12/236 (5%)
Query: 1753 KCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLV 1812
K + +SS E + + ++ QL R YP TR+DSSN P +FW G Q+V
Sbjct: 563 KSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMV 622
Query: 1813 ALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL-ERDLDSMDPAVY 1871
ALN+QT DL + +N M+E NG GY LKP + + + F P E +D +
Sbjct: 623 ALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPD----KHFDPFTEGIVDGIVANTL 678
Query: 1872 SLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCH--FRTKPIHRNTLNPMWNEQFLF--H 1927
S+ I+SGQ + S+ +EVD+ G+P+D+ F+TK N +NP+W E+ +
Sbjct: 679 SVKIISGQFL--SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKK 736
Query: 1928 VHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
V L LR AV E + RI+P++A++ GY ++ LRN N+ L + ++F+
Sbjct: 737 VVLPTLACLRIAVYEEGGKFI-GHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV 791
>gi|117320537 phospholipase C, gamma 2 [Homo sapiens]
Length = 1265
Score = 187 bits (476), Expect = 8e-47
Identities = 100/214 (46%), Positives = 139/214 (64%), Gaps = 7/214 (3%)
Query: 1332 FLVNCQGEHCTYD--EILSIIQKF-EPSISMCHQGLMSFEGFARFLMDKENFASKNDESQ 1388
FL++ Q EH D ++ + KF + ++ + + + F +L +EN
Sbjct: 249 FLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDA 308
Query: 1389 ENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMP 1448
+++++ PLS+Y+I SSHNTYLTG QL+ ESS E Y + L GCR +ELDCWDG DG P
Sbjct: 309 VDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKP 368
Query: 1449 IIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEK 1508
+IYHG T TTKI F +VV+AI AF+ S P+I+SIE HCS+ QQR MA+ FK VFG+
Sbjct: 369 VIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVFGDL 428
Query: 1509 LVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKL 1542
L+TK T+ S D LPSP QLR+K+++K+KKL
Sbjct: 429 LLTK---PTEASAD-QLPSPSQLREKIIIKHKKL 458
Score = 128 bits (322), Expect = 6e-29
Identities = 82/252 (32%), Positives = 131/252 (51%), Gaps = 17/252 (6%)
Query: 1741 PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPN 1800
PT+ + P I S E A + R+ L ++ L R YP R+DSSN +
Sbjct: 939 PTSKTKDNLENPDFREIRSFVETKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYD 998
Query: 1801 PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE 1860
P WL G Q+VALN+QT D + +N A+F NG GYVL+P + +K+ P+
Sbjct: 999 PFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESM------RTEKYDPMP 1052
Query: 1861 RDLDSMDPAVYSLTI-VSGQNVCP--SNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLN 1917
+S + +LT+ V G P S+ P +EV++ G D+ F+T ++ N L+
Sbjct: 1053 P--ESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLS 1110
Query: 1918 PMW---NEQFLFHVHFEDLVFLRFAVVENNSSA---VTAQRIIPLKALKRGYRHLQLRNL 1971
P+W E+ F ++ +L FLRF V E + + A P+KA+K G+R + L+N
Sbjct: 1111 PIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNG 1170
Query: 1972 HNEVLEISSLFI 1983
++E +E++SL +
Sbjct: 1171 YSEDIELASLLV 1182
>gi|19115964 phospholipase C delta 3 [Homo sapiens]
Length = 789
Score = 182 bits (462), Expect = 3e-45
Identities = 103/263 (39%), Positives = 150/263 (57%), Gaps = 23/263 (8%)
Query: 1328 QLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDES 1387
+L +FL + E T +IQ +E + + LM+ +GF +L+ E A N +
Sbjct: 274 ELLEFLEDQGEEGATLARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDNTHT 333
Query: 1388 QENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGM 1447
+++ PL++Y+I SSHNTYLT Q+ G SS E Y + QGCR VELDCW+G G
Sbjct: 334 CV-FQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGE 392
Query: 1448 PIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGE 1507
P+IYHGHTLT+KI F++VV+A+ AF S P+I+S+ENHC L QQ MA T+ G+
Sbjct: 393 PVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGD 452
Query: 1508 KLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAY 1567
LVT+ L D + LPSP+QL+ +VL+K KKL A ++
Sbjct: 453 MLVTQAL---DSPNPEELPSPEQLKGRVLVKGKKLPA-------------------ARSE 490
Query: 1568 NGGNANPRPANNEEEEDEEDEYD 1590
+G + R E++E+EE+E +
Sbjct: 491 DGRALSDREEEEEDDEEEEEEVE 513
Score = 132 bits (332), Expect = 4e-30
Identities = 79/243 (32%), Positives = 120/243 (49%), Gaps = 15/243 (6%)
Query: 1752 PKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQL 1811
P+ +SSL+E AK+L R +H A QL R YP R++S+N +P W G QL
Sbjct: 550 PQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQL 609
Query: 1812 VALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVY 1871
VALN+QT + LNA F NG CGYVLKP L Q S + +
Sbjct: 610 VALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACL-------RQPDSTFDPEYPGPPRTTL 662
Query: 1872 SLTIVSGQ-----NVCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLF 1926
S+ +++ Q N +S+ P + +++ G+P D T + N NP W + F
Sbjct: 663 SIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPADCARQETDYVLNNGFNPRWGQTLQF 722
Query: 1927 HVHFEDLVFLRFAVVENNSSA---VTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
+ +L +RF V + ++++ Q +PL +LK+GYRH+ L + L ++LFI
Sbjct: 723 QLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFI 782
Query: 1984 NSR 1986
R
Sbjct: 783 QIR 785
>gi|14249340 phospholipase C, delta 4 [Homo sapiens]
Length = 762
Score = 177 bits (450), Expect = 8e-44
Identities = 122/353 (34%), Positives = 177/353 (50%), Gaps = 72/353 (20%)
Query: 1326 ILQLNDFLVNCQGEH-CTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKN 1384
+L+ DFL Q E CT + L +I ++EPS S + ++S +GF +L K+ N
Sbjct: 224 LLEFLDFLQEEQKERDCTSELALELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIF-N 282
Query: 1385 DESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD 1444
+++ PL++Y+I SSHNTYL G QL G+SSVE Y + L +GCR VE+D WDG
Sbjct: 283 PACLPIYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGP 342
Query: 1445 DGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTV 1504
G P++YHGHTLT++I FK+VV + + AF SD P+I+S+E HCS QQ+ MA +
Sbjct: 343 SGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEI 402
Query: 1505 FGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQV 1564
GE+L++ L D LPSP++LR+K+L+K KKL +
Sbjct: 403 LGEQLLSTTL---DGVLPTQLPSPEELRRKILVKGKKLTLEE------------------ 441
Query: 1565 QAYNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIP 1624
+ E E+EE E + + L+ ++ E PE + N LQ
Sbjct: 442 --------------DLEYEEEEAEPELEESELALESQFETEPEPQEQN--LQ-------- 477
Query: 1625 KRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKF 1677
NK D+ KK + P LS LVIY ++V F
Sbjct: 478 -----------NK--------------DKKKKSKPILCPALSSLVIYLKSVSF 505
Score = 135 bits (341), Expect = 4e-31
Identities = 79/237 (33%), Positives = 116/237 (48%), Gaps = 13/237 (5%)
Query: 1755 YHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVAL 1814
Y ISS +E AKRL + + QH QL R YP+ R DSSN NP W G Q+VA+
Sbjct: 518 YEISSFSETKAKRLIKEAGNEFVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAM 577
Query: 1815 NYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLT 1874
N QT L + + F NGGCGYVLKP L D + F P E+ + +
Sbjct: 578 NMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRD----IQSSFHP-EKPISPFKAQTLLIQ 632
Query: 1875 IVSGQNV-----CPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFHVH 1929
++SGQ + S+ P ++V + G+ LD+ T + N NP W + F V
Sbjct: 633 VISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDTARQETNYVENNGFNPYWGQTLCFRVL 692
Query: 1930 FEDLVFLRFAVVE---NNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
+L LRF V++ + + Q +P +++GYRH+ L + L +S+F+
Sbjct: 693 VPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQGYRHIHLLSKDGISLRPASIFV 749
>gi|95147333 phospholipase C, beta 2 [Homo sapiens]
Length = 1185
Score = 177 bits (450), Expect = 8e-44
Identities = 110/252 (43%), Positives = 139/252 (55%), Gaps = 9/252 (3%)
Query: 1344 DEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYI 1403
D++ +I K+EPS +G +S EG FL EN D+ + ++ PL++Y+I
Sbjct: 265 DQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLH-HDMTQPLNHYFI 323
Query: 1404 ESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG--DDGMPIIYHGHTLTTKIP 1461
SSHNTYLT Q G SS E+Y QVLL GCR VELDCW G D PII HG T+TT I
Sbjct: 324 NSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIF 383
Query: 1462 FKEVVEAIDRSAFINSDLPIIISIENHCSLP-QQRKMAEIFKTVFGEKLVTKFLFETDFS 1520
FKE +EAI SAF S PII+S ENH P QQ KMAE +T+FG+ L+T+ L +
Sbjct: 384 FKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLK 443
Query: 1521 DDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGN----ANPRP 1576
LPSP+ LR K+L+KNKK P K + + G A
Sbjct: 444 PGVPLPSPEDLRGKILIKNKK-NQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEG 502
Query: 1577 ANNEEEEDEEDE 1588
EEEE EE+E
Sbjct: 503 TELEEEEVEEEE 514
Score = 134 bits (336), Expect = 1e-30
Identities = 99/262 (37%), Positives = 142/262 (54%), Gaps = 17/262 (6%)
Query: 1732 WEESSSPLN---PTTSLSAIIRTPK--CYHISSLNENAAKRLCRRYSQKLTQHTACQLLR 1786
+EE SS +N PT +S K Y ISS E A L + S + + Q+ R
Sbjct: 543 YEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSR 602
Query: 1787 TYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLW 1846
YP TR+DSSN P MFW G Q+VALN+QT DLP+ N A+FE NG GY+LK +
Sbjct: 603 IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMR 662
Query: 1847 DKNCPMYQKFSPLERD-LDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLD-SC 1904
+ ++F+P D +D + S+T++SGQ + S +EV++ G+P D
Sbjct: 663 RPD----KQFNPFSVDRIDVVVATTLSITVISGQFL--SERSVRTYVEVELFGLPGDPKR 716
Query: 1905 HFRTK-PIHRNTLNPMWNEQ-FLFH-VHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKR 1961
+RTK N++NP+W E+ F+F + +L LR AV+E + + RIIP+ AL
Sbjct: 717 RYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFL-GHRIIPINALNS 775
Query: 1962 GYRHLQLRNLHNEVLEISSLFI 1983
GY HL L + N L + +LFI
Sbjct: 776 GYHHLCLHSESNMPLTMPALFI 797
>gi|25188201 phospholipase C, zeta 1 [Homo sapiens]
Length = 608
Score = 176 bits (445), Expect = 3e-43
Identities = 91/196 (46%), Positives = 130/196 (66%), Gaps = 9/196 (4%)
Query: 1349 IIQKFEP--SISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYIESS 1406
IIQK+EP + HQ MS EGF R++ +E KN E ++ +++ PL+ Y+I SS
Sbjct: 113 IIQKYEPIEEVRKAHQ--MSLEGFTRYMDSRECLLFKN-ECRKVYQDMTHPLNDYFISSS 169
Query: 1407 HNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVV 1466
HNTYL QL G S + Y L++GCR +E+DCWDG P++YHG+TLT+K+ FK V+
Sbjct: 170 HNTYLVSDQLLGPSDLWGYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVI 229
Query: 1467 EAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLP 1526
+AI + AF+ SD P+++S+ENHCS QQ MA+ + FGE L++ L DF D LP
Sbjct: 230 QAIHKYAFMTSDYPVVLSLENHCSTAQQEVMADNLQATFGESLLSDML--DDFPD--TLP 285
Query: 1527 SPDQLRKKVLLKNKKL 1542
SP+ L+ K+L+KNKK+
Sbjct: 286 SPEALKFKILVKNKKI 301
Score = 131 bits (329), Expect = 9e-30
Identities = 81/233 (34%), Positives = 122/233 (52%), Gaps = 14/233 (6%)
Query: 1758 SSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALNYQ 1817
+S+ E A++L + + HT + R YP ATR DSSN NP FW G Q+VALN+Q
Sbjct: 377 NSIGETQARKLSKLRVHEFIFHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQ 436
Query: 1818 TDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTIVS 1877
T LP+ L F NGG GY+LKP L + F+P ++ P ++ ++S
Sbjct: 437 TPGLPMDLQNGKFLDNGGSGYILKPHFLRESK----SYFNP--SNIKEGMPITLTIRLIS 490
Query: 1878 GQNV---CPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFHVHFEDLV 1934
G + S++ G + ++V G+P D +T+ I +N +P WNE F F +H +L
Sbjct: 491 GIQLPLTHSSSNKGDSLVIIEVFGVPNDQMKQQTRVIKKNAFSPRWNETFTFIIHVPELA 550
Query: 1935 FLRFAVVENN----SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
+RF VVE + Q +PL + +GYR + L + E LE +SLF+
Sbjct: 551 LIRF-VVEGQGLIAGNEFLGQYTLPLLCMNKGYRRIPLFSRMGESLEPASLFV 602
>gi|221219000 phospholipase C-like 2 isoform 1 [Homo sapiens]
Length = 1127
Score = 170 bits (431), Expect = 1e-41
Identities = 86/211 (40%), Positives = 134/211 (63%), Gaps = 5/211 (2%)
Query: 1340 HCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLS 1399
H + L II K+EPS +G +S +GF +LM + + + E ++ ++++ PLS
Sbjct: 375 HINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIF-DPEHKKVCQDMKQPLS 433
Query: 1400 YYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTK 1459
+Y+I SSHNTYL Q +G S + Y + L GCRSVELD WDG D P+IY GHT+T++
Sbjct: 434 HYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQ 493
Query: 1460 IPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDF 1519
I F+ V++ I++ AF S+ P+I+ +ENHCS+ QQ+ M + K + G+KL T +
Sbjct: 494 IVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYT----TSPN 549
Query: 1520 SDDPMLPSPDQLRKKVLLKNKKLKAHQTPVD 1550
++ LPSPD L+ K+L+K KKL ++ + V+
Sbjct: 550 VEESYLPSPDVLKGKILIKAKKLSSNCSGVE 580
Score = 141 bits (355), Expect = 8e-33
Identities = 81/241 (33%), Positives = 128/241 (53%), Gaps = 13/241 (5%)
Query: 1753 KCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLV 1812
K + + S NE A + + L R +P+ RIDSSN NP FW G Q+V
Sbjct: 641 KYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIV 700
Query: 1813 ALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD-LDSMDPAVY 1871
A+N+QT L + LN F NG CGYVL+P ++ ++ FS +D + + P +
Sbjct: 701 AMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREE----VSFFSANTKDSVPGVSPQLL 756
Query: 1872 SLTIVSGQNVCPSNSMGS------PCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFL 1925
+ I+SGQN G+ P + V++ G+P D RTK +H+N P+++E F
Sbjct: 757 HIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFE 816
Query: 1926 FHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
F ++ +L +RF V++++ Q IP + L+ GYRH+ L++L EVL +SLF+
Sbjct: 817 FQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFV 876
Query: 1984 N 1984
+
Sbjct: 877 H 877
>gi|163644311 phospholipase C-like 2 isoform 2 [Homo sapiens]
Length = 1001
Score = 170 bits (431), Expect = 1e-41
Identities = 86/211 (40%), Positives = 134/211 (63%), Gaps = 5/211 (2%)
Query: 1340 HCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLS 1399
H + L II K+EPS +G +S +GF +LM + + + E ++ ++++ PLS
Sbjct: 249 HINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIF-DPEHKKVCQDMKQPLS 307
Query: 1400 YYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTK 1459
+Y+I SSHNTYL Q +G S + Y + L GCRSVELD WDG D P+IY GHT+T++
Sbjct: 308 HYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQ 367
Query: 1460 IPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDF 1519
I F+ V++ I++ AF S+ P+I+ +ENHCS+ QQ+ M + K + G+KL T +
Sbjct: 368 IVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYT----TSPN 423
Query: 1520 SDDPMLPSPDQLRKKVLLKNKKLKAHQTPVD 1550
++ LPSPD L+ K+L+K KKL ++ + V+
Sbjct: 424 VEESYLPSPDVLKGKILIKAKKLSSNCSGVE 454
Score = 141 bits (355), Expect = 8e-33
Identities = 81/241 (33%), Positives = 128/241 (53%), Gaps = 13/241 (5%)
Query: 1753 KCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLV 1812
K + + S NE A + + L R +P+ RIDSSN NP FW G Q+V
Sbjct: 515 KYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIV 574
Query: 1813 ALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD-LDSMDPAVY 1871
A+N+QT L + LN F NG CGYVL+P ++ ++ FS +D + + P +
Sbjct: 575 AMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREE----VSFFSANTKDSVPGVSPQLL 630
Query: 1872 SLTIVSGQNVCPSNSMGS------PCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFL 1925
+ I+SGQN G+ P + V++ G+P D RTK +H+N P+++E F
Sbjct: 631 HIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFE 690
Query: 1926 FHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFI 1983
F ++ +L +RF V++++ Q IP + L+ GYRH+ L++L EVL +SLF+
Sbjct: 691 FQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFV 750
Query: 1984 N 1984
+
Sbjct: 751 H 751
>gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]
Length = 1095
Score = 162 bits (411), Expect = 3e-39
Identities = 86/221 (38%), Positives = 134/221 (60%), Gaps = 11/221 (4%)
Query: 1327 LQLNDFLVNCQGE----HCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFAS 1382
L ND ++ + E H T D L II+++E S +G ++ +GF ++L+ E
Sbjct: 330 LDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSE--CD 387
Query: 1383 KNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCW 1441
D Q+ + +++ PLS+YYI +SHNTYL Q +G + + Y + L GCRSVELD
Sbjct: 388 IFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVS 447
Query: 1442 DGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIF 1501
DG D PI+ + + +TT + F+ V+E I++ AF+ S+ P+I+ + NHCSLPQQ+ MA+
Sbjct: 448 DGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQM 507
Query: 1502 KTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKL 1542
K VFG KL T E + LPSP++L++ +++K KKL
Sbjct: 508 KKVFGNKLYT----EAPLPSESYLPSPEKLKRMIIVKGKKL 544
Score = 145 bits (365), Expect = 6e-34
Identities = 82/261 (31%), Positives = 135/261 (51%), Gaps = 13/261 (4%)
Query: 1749 IRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHG 1808
+++ + + S +E A R+ Y + + L R YP+A RIDSSN NP FW G
Sbjct: 604 MKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCG 663
Query: 1809 IQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD-LDSMD 1867
Q+VA+N+QT + L+ F NGGCGYVL+P ++ D+ FS + L +
Sbjct: 664 CQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDE----VSYFSANTKGILPGVS 719
Query: 1868 PAVYSLTIVSGQN------VCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWN 1921
P + I+SGQN C + P + +++ G+P D RTK + +N+ NP+++
Sbjct: 720 PLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFD 779
Query: 1922 EQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEIS 1979
E F F V+ +L +RF V++++ Q IP + L+ GYRH+ LR+ +++E
Sbjct: 780 ETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHV 839
Query: 1980 SLFINSRRMEENSSGNTMSAS 2000
+LF++ + G S
Sbjct: 840 TLFVHIAITNRSGGGKAQKRS 860
>gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens]
Length = 997
Score = 162 bits (411), Expect = 3e-39
Identities = 86/221 (38%), Positives = 134/221 (60%), Gaps = 11/221 (4%)
Query: 1327 LQLNDFLVNCQGE----HCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFAS 1382
L ND ++ + E H T D L II+++E S +G ++ +GF ++L+ E
Sbjct: 232 LDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSE--CD 289
Query: 1383 KNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCW 1441
D Q+ + +++ PLS+YYI +SHNTYL Q +G + + Y + L GCRSVELD
Sbjct: 290 IFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVS 349
Query: 1442 DGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIF 1501
DG D PI+ + + +TT + F+ V+E I++ AF+ S+ P+I+ + NHCSLPQQ+ MA+
Sbjct: 350 DGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQM 409
Query: 1502 KTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKL 1542
K VFG KL T E + LPSP++L++ +++K KKL
Sbjct: 410 KKVFGNKLYT----EAPLPSESYLPSPEKLKRMIIVKGKKL 446
Score = 145 bits (365), Expect = 6e-34
Identities = 82/261 (31%), Positives = 135/261 (51%), Gaps = 13/261 (4%)
Query: 1749 IRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHG 1808
+++ + + S +E A R+ Y + + L R YP+A RIDSSN NP FW G
Sbjct: 506 MKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCG 565
Query: 1809 IQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD-LDSMD 1867
Q+VA+N+QT + L+ F NGGCGYVL+P ++ D+ FS + L +
Sbjct: 566 CQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDE----VSYFSANTKGILPGVS 621
Query: 1868 PAVYSLTIVSGQN------VCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWN 1921
P + I+SGQN C + P + +++ G+P D RTK + +N+ NP+++
Sbjct: 622 PLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFD 681
Query: 1922 EQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEIS 1979
E F F V+ +L +RF V++++ Q IP + L+ GYRH+ LR+ +++E
Sbjct: 682 ETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHV 741
Query: 1980 SLFINSRRMEENSSGNTMSAS 2000
+LF++ + G S
Sbjct: 742 TLFVHIAITNRSGGGKAQKRS 762
>gi|11386139 phospholipase C beta 3 [Homo sapiens]
Length = 1234
Score = 160 bits (404), Expect = 2e-38
Identities = 89/196 (45%), Positives = 124/196 (63%), Gaps = 4/196 (2%)
Query: 1349 IIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYIESSHN 1408
+I+K+EP+ + MS EGF+R+L +EN E+ + ++ PLS Y+I SSHN
Sbjct: 275 LIEKYEPNQQFLERDQMSMEGFSRYLGGEENGILPL-EALDLSTDMTQPLSAYFINSSHN 333
Query: 1409 TYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG--DDGMPIIYHGHTLTTKIPFKEVV 1466
TYLT QL G SSVE+Y Q LL GCR VELD W G + P I HG T+TT++P ++V+
Sbjct: 334 TYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVL 393
Query: 1467 EAIDRSAFINSDLPIIISIENHC-SLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPML 1525
EAI +AF S P+I+S ENH S QQ KMAE +++FG+ L+ + L + + L
Sbjct: 394 EAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPL 453
Query: 1526 PSPDQLRKKVLLKNKK 1541
PSP L ++L+KNKK
Sbjct: 454 PSPQDLMGRILVKNKK 469
Score = 130 bits (328), Expect = 1e-29
Identities = 91/276 (32%), Positives = 141/276 (51%), Gaps = 11/276 (3%)
Query: 1744 SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLM 1803
S A + KC+ +SS E A + + ++ QL R YP TR+DSSN P +
Sbjct: 604 SFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQL 663
Query: 1804 FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL-ERD 1862
FW G QLVALN+QT D+ + LNA +FE NG GY+LKP + + + F P E
Sbjct: 664 FWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPD----KSFDPFTEVI 719
Query: 1863 LDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCH-FRTKPIHRNTLNPMWN 1921
+D + + ++SGQ + S+ +EVD+ G+P+D+ +RT+ N+ NP+W+
Sbjct: 720 VDGIVANALRVKVISGQFL--SDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWD 777
Query: 1922 EQ-FLF-HVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEIS 1979
E+ F F V L LR A E V RI+P+ A++ GY ++ LRN N+ L +
Sbjct: 778 EEPFDFPKVVLPTLASLRIAAFEEGGKFV-GHRILPVSAIRSGYHYVCLRNEANQPLCLP 836
Query: 1980 SLFINSRRMEENSSGNTMSASSMFNTEERKCLQTHR 2015
+L I + + + A ++ N + L R
Sbjct: 837 ALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQR 872
>gi|7662070 Ral GEF with PH domain and SH3 binding motif 1 [Homo
sapiens]
Length = 557
Score = 63.2 bits (152), Expect = 3e-09
Identities = 38/149 (25%), Positives = 75/149 (50%), Gaps = 9/149 (6%)
Query: 600 RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSR---KV 656
RFN+VS WV ILTA +++ + E+ S+ V +AK + N +++M ++ L+S ++
Sbjct: 97 RFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRL 156
Query: 657 LKMWQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEV 716
K W +++ D T L M++ ++ R+ + +P +P+ G++L +L +
Sbjct: 157 TKTWALLNRKDKTTFEKLDYLMSKEDNYKRTREYIRSLKMVPS---IPYLGIYLLDLIYI 213
Query: 717 ---LDGASGLMKLCPRYNSQEETLEFVAD 742
+ +M+ R N L +AD
Sbjct: 214 DSAYPASGSIMENEQRSNQMNNILRIIAD 242
>gi|32441283 Ral GEF with PH domain and SH3 binding motif 2 [Homo
sapiens]
Length = 583
Score = 59.7 bits (143), Expect = 3e-08
Identities = 38/149 (25%), Positives = 75/149 (50%), Gaps = 9/149 (6%)
Query: 600 RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSR---KV 656
RFN VS WV IL A +++ + EV S+ + AK + + N +A+M ++GL+S ++
Sbjct: 96 RFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRL 155
Query: 657 LKMWQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEV 716
K W + + D T L+ M++ ++ R ++ +L + C +P+ G++L +L +
Sbjct: 156 TKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYIS-SLKMTPC--IPYLGIYLSDLTYI 212
Query: 717 ---LDGASGLMKLCPRYNSQEETLEFVAD 742
+++ R N L ++D
Sbjct: 213 DSAYPSTGSILENEQRSNLMNNILRIISD 241
>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
Length = 1333
Score = 54.3 bits (129), Expect = 1e-06
Identities = 65/303 (21%), Positives = 128/303 (42%), Gaps = 43/303 (14%)
Query: 493 RMMLKERQPGPSVANSNALPSSSAGISK----ELIDLQPLIQFPEEVASILMEQEQTIYR 548
+ + ++ PG ++ ++ P+ IS+ E DL L P E+A L E +YR
Sbjct: 740 KKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTL--HPIEIARQLTLLESDLYR 797
Query: 549 RVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNA--LEDLVMRFNEVSS 606
V P + + S+ T ++ E N+ L ++ ++
Sbjct: 798 AVQP------------------------SELVGSVWTKEDKEINSPNLLKMIRHTTNLTL 833
Query: 607 WVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQS 666
W I+ ++EE+ V S ++ + + + N+N V+E ++ + S V ++ +Q
Sbjct: 834 WFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQI 893
Query: 667 DIETMRSLKDAMAQHE-SSCEYRKVVTRALHI-PGCKVVPFCGVFLKELCEVLDGASGLM 724
+ L++A HE S Y+K + + I P C VPF G++L + + +G ++
Sbjct: 894 PSRQKKILEEA---HELSEDHYKKYLAKLRSINPPC--VPFFGIYLTNILKTEEGNPEVL 948
Query: 725 KLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRSLETD 784
K + VA+ +G+ +Q+ QN ES + F+ + S+E +
Sbjct: 949 KRHGKELINFSKRRKVAEITGE---IQQY-QNQPYCLRVESDIKRFFENLNPMGNSMEKE 1004
Query: 785 EED 787
D
Sbjct: 1005 FTD 1007
>gi|213385270 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 1 [Homo sapiens]
Length = 690
Score = 53.5 bits (127), Expect = 2e-06
Identities = 44/188 (23%), Positives = 81/188 (43%), Gaps = 31/188 (16%)
Query: 532 PEEVASILMEQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEH 591
P E+A L E +RR+ DY ++ C + P L+ SI+
Sbjct: 153 PIELAEHLTFLEHKSFRRISFTDYQSYVIHG-----CLENNPTLERSIAL---------- 197
Query: 592 NALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGL 651
FN +S WV ++L+ + +++ EV + ++VAK + N+N +M + GL
Sbjct: 198 ---------FNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGL 248
Query: 652 RSRKVLKMWQFMDQSDIETMRS---LKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGV 708
+ ++ + E ++ + + ++ + + C YRK G K +P GV
Sbjct: 249 SHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFA---DCDGFK-IPILGV 304
Query: 709 FLKELCEV 716
LK+L V
Sbjct: 305 HLKDLIAV 312
>gi|24762239 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 1 [Homo sapiens]
Length = 690
Score = 53.5 bits (127), Expect = 2e-06
Identities = 44/188 (23%), Positives = 81/188 (43%), Gaps = 31/188 (16%)
Query: 532 PEEVASILMEQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEH 591
P E+A L E +RR+ DY ++ C + P L+ SI+
Sbjct: 153 PIELAEHLTFLEHKSFRRISFTDYQSYVIHG-----CLENNPTLERSIAL---------- 197
Query: 592 NALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGL 651
FN +S WV ++L+ + +++ EV + ++VAK + N+N +M + GL
Sbjct: 198 ---------FNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGL 248
Query: 652 RSRKVLKMWQFMDQSDIETMRS---LKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGV 708
+ ++ + E ++ + + ++ + + C YRK G K +P GV
Sbjct: 249 SHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFA---DCDGFK-IPILGV 304
Query: 709 FLKELCEV 716
LK+L V
Sbjct: 305 HLKDLIAV 312
>gi|7662334 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 2 [Homo sapiens]
Length = 689
Score = 53.5 bits (127), Expect = 2e-06
Identities = 44/188 (23%), Positives = 81/188 (43%), Gaps = 31/188 (16%)
Query: 532 PEEVASILMEQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEH 591
P E+A L E +RR+ DY ++ C + P L+ SI+
Sbjct: 153 PIELAEHLTFLEHKSFRRISFTDYQSYVIHG-----CLENNPTLERSIAL---------- 197
Query: 592 NALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGL 651
FN +S WV ++L+ + +++ EV + ++VAK + N+N +M + GL
Sbjct: 198 ---------FNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGL 248
Query: 652 RSRKVLKMWQFMDQSDIETMRS---LKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGV 708
+ ++ + E ++ + + ++ + + C YRK G K +P GV
Sbjct: 249 SHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFA---DCDGFK-IPILGV 304
Query: 709 FLKELCEV 716
LK+L V
Sbjct: 305 HLKDLIAV 312
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 49.3 bits (116), Expect = 4e-05
Identities = 38/152 (25%), Positives = 74/152 (48%), Gaps = 11/152 (7%)
Query: 543 EQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALED-----L 597
+Q ++++ PV +L +R LG + +++P +S S S T N ++D L
Sbjct: 1480 QQELFQKCHPVHFLN--SRALGVMDKSTAIPKASSSESLSAKTCSLFLPNYVQDKYLLQL 1537
Query: 598 VMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVL 657
+ ++VS+WV I+T+ + + + + S + +AK C+ N+ M+ L+GL V
Sbjct: 1538 LRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVR 1597
Query: 658 K--MWQFMDQSDIETMRSLK--DAMAQHESSC 685
+ W+ + E M LK + + +S C
Sbjct: 1598 QSPAWRILPAKIAEVMEELKAVEVFLKSDSLC 1629
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,748,958
Number of Sequences: 37866
Number of extensions: 4240244
Number of successful extensions: 18249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 17496
Number of HSP's gapped (non-prelim): 620
length of query: 2302
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2184
effective length of database: 13,779,330
effective search space: 30094056720
effective search space used: 30094056720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.