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Search of human proteins with 239745208
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo
sapiens]
(463 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239750846 PREDICTED: hypothetical protein [Homo sapiens] 947 0.0
gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo ... 947 0.0
gi|239756319 PREDICTED: hypothetical protein [Homo sapiens] 944 0.0
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 50 3e-06
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 50 3e-06
gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo ... 50 4e-06
gi|239750438 PREDICTED: hypothetical protein [Homo sapiens] 50 4e-06
gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo ... 50 4e-06
gi|109452587 family with sequence similarity 98, member B isofor... 45 1e-04
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 45 2e-04
gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo ... 44 2e-04
gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo ... 44 2e-04
gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo ... 44 4e-04
gi|119395750 keratin 1 [Homo sapiens] 43 5e-04
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 43 7e-04
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 43 7e-04
gi|31542255 hypothetical protein LOC140706 [Homo sapiens] 43 7e-04
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 42 0.001
gi|57864582 hornerin [Homo sapiens] 42 0.001
gi|55956899 keratin 9 [Homo sapiens] 42 0.001
gi|239749709 PREDICTED: hypothetical protein [Homo sapiens] 41 0.003
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ... 40 0.003
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap... 40 0.003
gi|62122917 filaggrin family member 2 [Homo sapiens] 40 0.004
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 40 0.004
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s... 40 0.004
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006
>gi|239750846 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 947 bits (2448), Expect = 0.0
Identities = 463/463 (100%), Positives = 463/463 (100%)
Query: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA
Sbjct: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV
Sbjct: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180
GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL
Sbjct: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180
Query: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240
VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL
Sbjct: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240
Query: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300
AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ
Sbjct: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300
Query: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360
TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH
Sbjct: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360
Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR
Sbjct: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
Query: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463
REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC
Sbjct: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463
>gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo
sapiens]
Length = 463
Score = 947 bits (2448), Expect = 0.0
Identities = 463/463 (100%), Positives = 463/463 (100%)
Query: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA
Sbjct: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV
Sbjct: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180
GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL
Sbjct: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180
Query: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240
VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL
Sbjct: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240
Query: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300
AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ
Sbjct: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300
Query: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360
TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH
Sbjct: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360
Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR
Sbjct: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
Query: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463
REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC
Sbjct: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463
>gi|239756319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 944 bits (2440), Expect = 0.0
Identities = 462/463 (99%), Positives = 462/463 (99%)
Query: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
MGGGEWG GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA
Sbjct: 1 MGGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV
Sbjct: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180
GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL
Sbjct: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180
Query: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240
VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL
Sbjct: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240
Query: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300
AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ
Sbjct: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300
Query: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360
TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH
Sbjct: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360
Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR
Sbjct: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
Query: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463
REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC
Sbjct: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463
>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 54.7 bits (130), Expect = 2e-07
Identities = 128/435 (29%), Positives = 154/435 (35%), Gaps = 104/435 (23%)
Query: 18 ASEVVGR-RTRGGVGSCGSVHRHRVQ---------GGGRAGERFAGGGGAALAGGCLRGR 67
A+ V GR R R G+G SV Q G AG GG A AGG L G
Sbjct: 783 AAAVSGRGRLRDGLGRVASVAAEGAQVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGA 842
Query: 68 GAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127
+R R+ R + G R R GR+G G G GG+R+ RH
Sbjct: 843 VVQRMRQRRVRAGRRRVGARAVAAAGRQGA-GAGGGGRRV---------RHG-------- 884
Query: 128 HGDGGGRVDHA--GGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPP-RHLVFPR 184
HG G + A H+ PA A AA G V G HR G +G P RH
Sbjct: 885 HGHGAAVLQRAPCRQQRHLAPAAAAAAAQG---VRAAQGRAHR-PGAQGAPSHRH----- 935
Query: 185 DDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244
G R R AA + GG H + A GR+R G Q
Sbjct: 936 -----RPGARGRRSRRRAAVALAGGAHPARA-ALGRRR------------------GGGQ 971
Query: 245 VVGLK--HLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQTV 302
VG + H LA Q V + V AA R A R PR L A T
Sbjct: 972 AVGARAAHQARLAGGQ---VDQVVVAA---RAGDADGVRGRRPRRL----------ALTA 1015
Query: 303 LPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRL--LVAVRVAAGPRH 360
P L L + D LVD+ R H + R +G D R L AVRVAA
Sbjct: 1016 RPELEELLERLHGLQDGLVDVL-RHHRVVRLHPQLAGACDGRAAHLDEEEAVRVAAA--- 1071
Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
AD +L R L V + E ARR + H + A G
Sbjct: 1072 --------------ADVHELQRHRRLLAVELHEADGARRQAQTVHPRQVLALAQTLGLQV 1117
Query: 421 REPGLLSSAPQRPVP 435
P L + +R VP
Sbjct: 1118 HLPHL--TVGERAVP 1130
Score = 37.0 bits (84), Expect = 0.038
Identities = 77/252 (30%), Positives = 91/252 (36%), Gaps = 37/252 (14%)
Query: 43 GGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG--GDGRWQRRQRGHGGRRGLNGH 100
GGGR AALA R G RV G G+GR GHGG R G
Sbjct: 223 GGGRLVAPSRADTHAALAA--FPERDIFHGGRVVALGVVGEGR------GHGGDR--RGG 272
Query: 101 GDGGQRLARRVAQRLQRHAVGAVVATR------HGDGGGRVDHAGGAIHVWPAGAQRAAH 154
G+G +A R+ +GA V R G + H +H +RA H
Sbjct: 273 GEGLGTVAAAAPLRVCADDLGAAVGVRGLAGLQEGLDSRHLLHEAQPLH----ARRRAGH 328
Query: 155 GSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQ 214
G RL G G HL ++ G RG Q GG G Q
Sbjct: 329 AGSFWLR--GGRDRLRRGGGHTKSHLGVV--TIVPGR-----RGRAAGGQERGGRGRRRQ 379
Query: 215 VRARGRQRAEPQLGLL-LQVLRRVGWLAGRQVVGLKHLEALAAP-QEAAVLEHVPAAWVQ 272
RGR++A P L + + VL G L R L H P Q A H PAA Q
Sbjct: 380 QGRRGRRQAGPGLAKVDVDVL--AGALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQ 437
Query: 273 RPEAALAWLVRP 284
EA A RP
Sbjct: 438 --EALRAAAARP 447
Score = 35.4 bits (80), Expect = 0.11
Identities = 85/305 (27%), Positives = 94/305 (30%), Gaps = 106/305 (34%)
Query: 17 KASEVVGRRTRGGVGSC---GSVHRHRVQGGGRA-----------GERFAGGGGAALAGG 62
+A + RR G GS G R R +GGG G R GG G
Sbjct: 316 EAQPLHARRRAGHAGSFWLRGGRDRLR-RGGGHTKSHLGVVTIVPGRRGRAAGGQERGG- 373
Query: 63 CLRGRGAERGRRVREQGGDG---------------RWQ---------------------- 85
RGR ++GRR R Q G G RWQ
Sbjct: 374 --RGRRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAGQAGQPLQGQARGPHR 431
Query: 86 -----------RRQRGHGGR----RGLNGHG-DGGQRLA------RRVAQRLQ------- 116
R HG R RGL G G +G RLA R LQ
Sbjct: 432 PAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGA 491
Query: 117 -RHAVGAVVATRHGD----GGGRVDHAGGAIHVWPAGAQRAAH--GSQLVGERVGSGH-- 167
H + AV AT G G G V AG A PAG Q G G+RV GH
Sbjct: 492 HEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHVE 551
Query: 168 -----------RLHGGEGQPPR-HLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQV 215
LHG G P H+ L G L A R GG W
Sbjct: 552 VVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGG-CWPR 610
Query: 216 RARGR 220
R R R
Sbjct: 611 RPRRR 615
Score = 35.4 bits (80), Expect = 0.11
Identities = 67/207 (32%), Positives = 73/207 (35%), Gaps = 54/207 (26%)
Query: 7 GGGRQDWEPGKASEVVGRRTRGGVGS-CGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
GGG G + V GRR R G G R R QG R G R AG G A + L
Sbjct: 344 GGGHTKSHLGVVTIVPGRRGRAAGGQERGGRGRRRQQG--RRGRRQAGPGLAKVDVDVLA 401
Query: 66 GRGAER--------GRRVREQGGDGRWQRRQ-------------RGHGGR----RGLNGH 100
G R G+ + G R R R HG R RGL G
Sbjct: 402 GALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGA 461
Query: 101 G-DGGQRLA------RRVAQRLQ--------RHAVGAVVATRHGD----GGGRVDHAGGA 141
G +G RLA R LQ H + AV AT G G G V AG A
Sbjct: 462 GPEGAGRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNA 521
Query: 142 IHVWPAGAQRAAHGSQLVGERVGSGHR 168
PAG Q GE VG G R
Sbjct: 522 PERLPAGVQGC-------GEEVGRGAR 541
Score = 33.9 bits (76), Expect = 0.32
Identities = 49/178 (27%), Positives = 61/178 (34%), Gaps = 28/178 (15%)
Query: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
+ GG GGG P + V R R V V GR G AGGGG +
Sbjct: 824 VAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAG-AGGGGRRVR 882
Query: 61 GGCLRGRGAERGRRVREQ--------GGDGRWQRRQRGHGGRRGLNG-------HGDGGQ 105
G G + R+Q + R +G R G G G G+
Sbjct: 883 HGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRHRPGARGR 942
Query: 106 RLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERV 163
R RR A L A A A GGG+ A RAAH ++L G +V
Sbjct: 943 RSRRRAAVALAGGAHPARAALGRRRGGGQ------------AVGARAAHQARLAGGQV 988
>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 54.7 bits (130), Expect = 2e-07
Identities = 128/435 (29%), Positives = 154/435 (35%), Gaps = 104/435 (23%)
Query: 18 ASEVVGR-RTRGGVGSCGSVHRHRVQ---------GGGRAGERFAGGGGAALAGGCLRGR 67
A+ V GR R R G+G SV Q G AG GG A AGG L G
Sbjct: 783 AAAVSGRGRLRDGLGRVASVAAEGAQVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGA 842
Query: 68 GAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127
+R R+ R + G R R GR+G G G GG+R+ RH
Sbjct: 843 VVQRMRQRRVRAGRRRVGARAVAAAGRQGA-GAGGGGRRV---------RHG-------- 884
Query: 128 HGDGGGRVDHA--GGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPP-RHLVFPR 184
HG G + A H+ PA A AA G V G HR G +G P RH
Sbjct: 885 HGHGAAVLQRAPCRQQRHLAPAAAAAAAQG---VRAAQGRAHR-PGAQGAPSHRH----- 935
Query: 185 DDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244
G R R AA + GG H + A GR+R G Q
Sbjct: 936 -----RPGARGRRSRRRAAVALAGGAHPARA-ALGRRR------------------GGGQ 971
Query: 245 VVGLK--HLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQTV 302
VG + H LA Q V + V AA R A R PR L A T
Sbjct: 972 AVGARAAHQARLAGGQ---VDQVVVAA---RAGDADGVRGRRPRRL----------ALTA 1015
Query: 303 LPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRL--LVAVRVAAGPRH 360
P L L + D LVD+ R H + R +G D R L AVRVAA
Sbjct: 1016 RPELEELLERLHGLQDGLVDVL-RHHRVVRLHPQLAGACDGRAAHLDEEEAVRVAAA--- 1071
Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420
AD +L R L V + E ARR + H + A G
Sbjct: 1072 --------------ADVHELQRHRRLLAVELHEADGARRQAQTVHPRQVLALAQTLGLQV 1117
Query: 421 REPGLLSSAPQRPVP 435
P L + +R VP
Sbjct: 1118 HLPHL--TVGERAVP 1130
Score = 37.0 bits (84), Expect = 0.038
Identities = 77/252 (30%), Positives = 91/252 (36%), Gaps = 37/252 (14%)
Query: 43 GGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG--GDGRWQRRQRGHGGRRGLNGH 100
GGGR AALA R G RV G G+GR GHGG R G
Sbjct: 223 GGGRLVAPSRADTHAALAA--FPERDIFHGGRVVALGVVGEGR------GHGGDR--RGG 272
Query: 101 GDGGQRLARRVAQRLQRHAVGAVVATR------HGDGGGRVDHAGGAIHVWPAGAQRAAH 154
G+G +A R+ +GA V R G + H +H +RA H
Sbjct: 273 GEGLGTVAAAAPLRVCADDLGAAVGVRGLAGLQEGLDSRHLLHEAQPLH----ARRRAGH 328
Query: 155 GSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQ 214
G RL G G HL ++ G RG Q GG G Q
Sbjct: 329 AGSFWLR--GGRDRLRRGGGHTKSHLGVV--TIVPGR-----RGRAAGGQERGGRGRRRQ 379
Query: 215 VRARGRQRAEPQLGLL-LQVLRRVGWLAGRQVVGLKHLEALAAP-QEAAVLEHVPAAWVQ 272
RGR++A P L + + VL G L R L H P Q A H PAA Q
Sbjct: 380 QGRRGRRQAGPGLAKVDVDVL--AGALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQ 437
Query: 273 RPEAALAWLVRP 284
EA A RP
Sbjct: 438 --EALRAAAARP 447
Score = 35.4 bits (80), Expect = 0.11
Identities = 85/305 (27%), Positives = 94/305 (30%), Gaps = 106/305 (34%)
Query: 17 KASEVVGRRTRGGVGSC---GSVHRHRVQGGGRA-----------GERFAGGGGAALAGG 62
+A + RR G GS G R R +GGG G R GG G
Sbjct: 316 EAQPLHARRRAGHAGSFWLRGGRDRLR-RGGGHTKSHLGVVTIVPGRRGRAAGGQERGG- 373
Query: 63 CLRGRGAERGRRVREQGGDG---------------RWQ---------------------- 85
RGR ++GRR R Q G G RWQ
Sbjct: 374 --RGRRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAGQAGQPLQGQARGPHR 431
Query: 86 -----------RRQRGHGGR----RGLNGHG-DGGQRLA------RRVAQRLQ------- 116
R HG R RGL G G +G RLA R LQ
Sbjct: 432 PAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGA 491
Query: 117 -RHAVGAVVATRHGD----GGGRVDHAGGAIHVWPAGAQRAAH--GSQLVGERVGSGH-- 167
H + AV AT G G G V AG A PAG Q G G+RV GH
Sbjct: 492 HEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHVE 551
Query: 168 -----------RLHGGEGQPPR-HLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQV 215
LHG G P H+ L G L A R GG W
Sbjct: 552 VVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGG-CWPR 610
Query: 216 RARGR 220
R R R
Sbjct: 611 RPRRR 615
Score = 35.4 bits (80), Expect = 0.11
Identities = 67/207 (32%), Positives = 73/207 (35%), Gaps = 54/207 (26%)
Query: 7 GGGRQDWEPGKASEVVGRRTRGGVGS-CGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
GGG G + V GRR R G G R R QG R G R AG G A + L
Sbjct: 344 GGGHTKSHLGVVTIVPGRRGRAAGGQERGGRGRRRQQG--RRGRRQAGPGLAKVDVDVLA 401
Query: 66 GRGAER--------GRRVREQGGDGRWQRRQ-------------RGHGGR----RGLNGH 100
G R G+ + G R R R HG R RGL G
Sbjct: 402 GALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGA 461
Query: 101 G-DGGQRLA------RRVAQRLQ--------RHAVGAVVATRHGD----GGGRVDHAGGA 141
G +G RLA R LQ H + AV AT G G G V AG A
Sbjct: 462 GPEGAGRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNA 521
Query: 142 IHVWPAGAQRAAHGSQLVGERVGSGHR 168
PAG Q GE VG G R
Sbjct: 522 PERLPAGVQGC-------GEEVGRGAR 541
Score = 33.9 bits (76), Expect = 0.32
Identities = 49/178 (27%), Positives = 61/178 (34%), Gaps = 28/178 (15%)
Query: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
+ GG GGG P + V R R V V GR G AGGGG +
Sbjct: 824 VAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAG-AGGGGRRVR 882
Query: 61 GGCLRGRGAERGRRVREQ--------GGDGRWQRRQRGHGGRRGLNG-------HGDGGQ 105
G G + R+Q + R +G R G G G G+
Sbjct: 883 HGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRHRPGARGR 942
Query: 106 RLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERV 163
R RR A L A A A GGG+ A RAAH ++L G +V
Sbjct: 943 RSRRRAAVALAGGAHPARAALGRRRGGGQ------------AVGARAAHQARLAGGQV 988
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 50.4 bits (119), Expect = 3e-06
Identities = 56/174 (32%), Positives = 66/174 (37%), Gaps = 16/174 (9%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
GGE G + G G R+ GG G R GGG +G+R GG G +GG
Sbjct: 397 GGERGYRGRGGRGGDRGGYGGDRSGGGYGG------DRSSGGGYSGDRSGGGYGGDRSGG 450
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122
G G +RG G G R G+GG RG G GG R R G
Sbjct: 451 ---GYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG- 506
Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVG--SGHRLHGGEG 174
R G GG R + G G + GS G+R G G R GG G
Sbjct: 507 --GDRGGYGGDRGGYGGDRSRGGYGGDR--GGGSGYGGDRSGGYGGDRSGGGYG 556
Score = 46.2 bits (108), Expect = 6e-05
Identities = 53/173 (30%), Positives = 65/173 (37%), Gaps = 16/173 (9%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVG---SCGSVHRHRVQGGGRAGERFAGGGGAAL 59
GG+ GG + G R+ GG G S G R GGG G+R GG G
Sbjct: 416 GGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR--GGGYGGDR-GGGYGGDR 472
Query: 60 AGGCLRGRGAERGRRVREQGGD-GRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
GG RG G R GGD G + + G+GG RG G GG R
Sbjct: 473 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--------- 523
Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG 171
+ G R G G D +GG G G G+R G G ++ G
Sbjct: 524 SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 576
Score = 37.7 bits (86), Expect = 0.022
Identities = 36/109 (33%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRR-----TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGA 57
GG +GG R + + G R RGG G G + GG G+R GG G
Sbjct: 473 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGG 530
Query: 58 ALAGGCLRGRGAER-GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQ 105
GG G G +R G ++ G G R G+GG RG G GG+
Sbjct: 531 DRGGGS--GYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 577
Score = 33.1 bits (74), Expect = 0.55
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 12/93 (12%)
Query: 3 GGEWGG--GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
GG+ GG G + G G R+RGG G R G G G+R G GG
Sbjct: 499 GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG------DRGGGSGYGGDRSGGYGGDRSG 552
Query: 61 GGCLRGRGA----ERGRRVREQGGDGRWQRRQR 89
GG RG +RG + GG ++ QR
Sbjct: 553 GGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQR 585
Score = 32.0 bits (71), Expect = 1.2
Identities = 49/171 (28%), Positives = 55/171 (32%), Gaps = 32/171 (18%)
Query: 27 RGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-------GCLRGRGAERG------- 72
RGG GS R +GG R F G GG +G C A R
Sbjct: 323 RGG----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 378
Query: 73 ---RRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRL------QRHAVGAV 123
R GGD R RG+GG RG G G G R R + G
Sbjct: 379 PRPEDSRPSGGDFRG----RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 434
Query: 124 VATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEG 174
R G G G D +GG G G G+R G GG G
Sbjct: 435 SGDRSGGGYGG-DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYG 484
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 50.4 bits (119), Expect = 3e-06
Identities = 56/174 (32%), Positives = 66/174 (37%), Gaps = 16/174 (9%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
GGE G + G G R+ GG G R GGG +G+R GG G +GG
Sbjct: 400 GGERGYRGRGGRGGDRGGYGGDRSGGGYGG------DRSSGGGYSGDRSGGGYGGDRSGG 453
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122
G G +RG G G R G+GG RG G GG R R G
Sbjct: 454 ---GYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG- 509
Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVG--SGHRLHGGEG 174
R G GG R + G G + GS G+R G G R GG G
Sbjct: 510 --GDRGGYGGDRGGYGGDRSRGGYGGDR--GGGSGYGGDRSGGYGGDRSGGGYG 559
Score = 46.2 bits (108), Expect = 6e-05
Identities = 53/173 (30%), Positives = 65/173 (37%), Gaps = 16/173 (9%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVG---SCGSVHRHRVQGGGRAGERFAGGGGAAL 59
GG+ GG + G R+ GG G S G R GGG G+R GG G
Sbjct: 419 GGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR--GGGYGGDR-GGGYGGDR 475
Query: 60 AGGCLRGRGAERGRRVREQGGD-GRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
GG RG G R GGD G + + G+GG RG G GG R
Sbjct: 476 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--------- 526
Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG 171
+ G R G G D +GG G G G+R G G ++ G
Sbjct: 527 SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 579
Score = 37.7 bits (86), Expect = 0.022
Identities = 36/109 (33%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRR-----TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGA 57
GG +GG R + + G R RGG G G + GG G+R GG G
Sbjct: 476 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGG 533
Query: 58 ALAGGCLRGRGAER-GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQ 105
GG G G +R G ++ G G R G+GG RG G GG+
Sbjct: 534 DRGGGS--GYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 580
Score = 33.1 bits (74), Expect = 0.55
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 12/93 (12%)
Query: 3 GGEWGG--GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
GG+ GG G + G G R+RGG G R G G G+R G GG
Sbjct: 502 GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG------DRGGGSGYGGDRSGGYGGDRSG 555
Query: 61 GGCLRGRGA----ERGRRVREQGGDGRWQRRQR 89
GG RG +RG + GG ++ QR
Sbjct: 556 GGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQR 588
Score = 32.0 bits (71), Expect = 1.2
Identities = 49/171 (28%), Positives = 55/171 (32%), Gaps = 32/171 (18%)
Query: 27 RGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-------GCLRGRGAERG------- 72
RGG GS R +GG R F G GG +G C A R
Sbjct: 326 RGG----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 381
Query: 73 ---RRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRL------QRHAVGAV 123
R GGD R RG+GG RG G G G R R + G
Sbjct: 382 PRPEDSRPSGGDFRG----RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 437
Query: 124 VATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEG 174
R G G G D +GG G G G+R G GG G
Sbjct: 438 SGDRSGGGYGG-DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYG 487
>gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo
sapiens]
Length = 600
Score = 50.1 bits (118), Expect = 4e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 293 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 337
Query: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 338 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 387
Query: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
+R G HG G D GG R G+ G H GEG
Sbjct: 388 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 426
Query: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 427 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 481
Query: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
R+ L GR+ AL Q A+
Sbjct: 482 ERARLFHL-GRRCALANRAPALLRAQAAS 509
Score = 37.4 bits (85), Expect = 0.029
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 249 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 294
Query: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
GG V R R VGAV R HG + G V AGG HV
Sbjct: 295 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 353
Query: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
++A+ HG L G+ V GG G+P + L
Sbjct: 354 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 247 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 293
Query: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 294 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 344
Query: 212 LWQVRARGRQRA 223
VR R++A
Sbjct: 345 CGHVRVGVREQA 356
>gi|239750438 PREDICTED: hypothetical protein [Homo sapiens]
Length = 510
Score = 50.1 bits (118), Expect = 4e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 150 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 194
Query: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 195 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 244
Query: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
+R G HG G D GG R G+ G H GEG
Sbjct: 245 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 283
Query: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 284 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 338
Query: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
R+ L GR+ AL Q A+
Sbjct: 339 ERARLFHL-GRRCALANRAPALLRAQAAS 366
Score = 37.4 bits (85), Expect = 0.029
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151
Query: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
GG V R R VGAV R HG + G V AGG HV
Sbjct: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210
Query: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
++A+ HG L G+ V GG G+P + L
Sbjct: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150
Query: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201
Query: 212 LWQVRARGRQRA 223
VR R++A
Sbjct: 202 CGHVRVGVREQA 213
>gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo
sapiens]
Length = 457
Score = 50.1 bits (118), Expect = 4e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 150 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 194
Query: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 195 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 244
Query: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
+R G HG G D GG R G+ G H GEG
Sbjct: 245 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 283
Query: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 284 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 338
Query: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
R+ L GR+ AL Q A+
Sbjct: 339 ERARLFHL-GRRCALANRAPALLRAQAAS 366
Score = 37.4 bits (85), Expect = 0.029
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151
Query: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
GG V R R VGAV R HG + G V AGG HV
Sbjct: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210
Query: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
++A+ HG L G+ V GG G+P + L
Sbjct: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150
Query: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201
Query: 212 LWQVRARGRQRA 223
VR R++A
Sbjct: 202 CGHVRVGVREQA 213
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/102 (37%), Positives = 41/102 (40%), Gaps = 24/102 (23%)
Query: 2 GGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61
G G WGGG G RGG G G GGG G GGGG G
Sbjct: 334 GRGGWGGGG------------GGGGRGGGGGGGG---RGGWGGGGGGWGGGGGGGGGWGG 378
Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103
G GRG +GR + GG G G+GGR G G G G
Sbjct: 379 GGGGGRGGFQGR--GDYGGRG-------GYGGRGGYGGRGYG 411
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/105 (35%), Positives = 38/105 (36%), Gaps = 21/105 (20%)
Query: 2 GGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61
GGG GGGR W GG G G GGG G + GGGG G
Sbjct: 348 GGGGGGGGRGGWG-------------GGGGGWG--------GGGGGGGGWGGGGGGGRGG 386
Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQR 106
RG RG G GR G GG G G G GG R
Sbjct: 387 FQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
Score = 39.3 bits (90), Expect = 0.008
Identities = 41/135 (30%), Positives = 47/135 (34%), Gaps = 37/135 (27%)
Query: 40 RVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNG 99
R +GGG G GGGG GG G G RG GG G W G GG G G
Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGG---GGGGGRG---GWGGGGGGWGGGGGGGGGWGGGGG 381
Query: 100 HGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLV 159
G GG + GD GGR + G R +G +
Sbjct: 382 GGRGGFQ--------------------GRGDYGGRGGYGG-----------RGGYGGRGY 410
Query: 160 GERVGSGHRLHGGEG 174
G+ G G GG G
Sbjct: 411 GDPYGGGGGGGGGGG 425
Score = 38.9 bits (89), Expect = 0.010
Identities = 38/115 (33%), Positives = 42/115 (36%), Gaps = 16/115 (13%)
Query: 64 LRGRGAERGRRVREQGGDGR----WQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHA 119
L GR +RG R E WQ+RQ G GGR G G G GG R
Sbjct: 301 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGR----------GGG 350
Query: 120 VGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEG 174
G G GGG GG W G G Q G+ G G +GG G
Sbjct: 351 GGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGG--YGGRG 403
Score = 38.9 bits (89), Expect = 0.010
Identities = 32/81 (39%), Positives = 34/81 (41%), Gaps = 8/81 (9%)
Query: 27 RGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQR 86
RGG G G GGGR G GG G GG G G G GG GR
Sbjct: 335 RGGWGGGGG-------GGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGF 387
Query: 87 RQRG-HGGRRGLNGHGDGGQR 106
+ RG +GGR G G G G R
Sbjct: 388 QGRGDYGGRGGYGGRGGYGGR 408
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 44.7 bits (104), Expect = 2e-04
Identities = 65/217 (29%), Positives = 70/217 (32%), Gaps = 44/217 (20%)
Query: 8 GGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGR 67
GGR EP R RGG G + GGG GGGG G G
Sbjct: 708 GGRGGNEPPPPPPPF-RGARGGRSGGGPPNGRGGPGGG-----MVGGGGHRPHEGPGGGM 761
Query: 68 GAERGRRVRE--QGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVA 125
G G R E GG G R G GG G G GG R
Sbjct: 762 GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG----GGGGHR------------------- 798
Query: 126 TRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGS-----GHRLHGGEGQPPRHL 180
G GGG +G H P G A G + GS GHR H G G H
Sbjct: 799 PHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG 858
Query: 181 VFPRDDVLDGEGVLEARG------LRHAAQVVGGGGH 211
P D + G + RG H GGGGH
Sbjct: 859 HRPHD--VPGHRGHDHRGPPPHEHRGHDGPGHGGGGH 893
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/185 (27%), Positives = 60/185 (32%), Gaps = 40/185 (21%)
Query: 2 GGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61
GG G Q + PG + G GG G R G+ F G G + G
Sbjct: 632 GGPGGPKGMQHFPPGPGGPMPG--PHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRG 689
Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGR---------RGLNGHGDGGQRLARRVA 112
G +RG G G + R + G GG RG G G
Sbjct: 690 GPMRGGPGP---------GPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSG--------- 731
Query: 113 QRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG---SQLVGERVGSGHRL 169
G R G GGG V G H P G + G + G +GSGHR
Sbjct: 732 --------GGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP 783
Query: 170 HGGEG 174
H G G
Sbjct: 784 HEGPG 788
>gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo
sapiens]
Length = 594
Score = 44.3 bits (103), Expect = 2e-04
Identities = 125/487 (25%), Positives = 160/487 (32%), Gaps = 135/487 (27%)
Query: 44 GGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG-------GDGRWQRRQRGHG---- 92
GG+AG G G GC R + RG R G G W R++ HG
Sbjct: 33 GGQAGHPVVGDTGQ-FERGCARRHRSPRGHRHAVPGPRLQRALGGQAWAGRRQLHGFMLY 91
Query: 93 ------GRRG---LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIH 143
G RG + G G GG RLQ +VA G G G +DH+G +
Sbjct: 92 SGQQRDGHRGGHDVGGRGGGG---------RLQ------LVAGALGLGAGVLDHSGLRVA 136
Query: 144 VWPAGAQR----AAHGSQLVGE--RVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEAR 197
V A + A H + E RV L G G+P R V +G+ +LEA
Sbjct: 137 VGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPAR--------VAEGQDLLEAG 188
Query: 198 GLRHAAQVVG----GGGHLWQVRARGRQR-----------------AEPQLGLLLQVLRR 236
G A Q+ G + +V A G Q E Q LL+Q +
Sbjct: 189 GRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQALLVQAAQH 248
Query: 237 ----------------------VGWLAGRQVVGLKHLEALAAPQEAAVLEHVPAAWV-QR 273
+G G + GL +L + A AA H P Q
Sbjct: 249 CVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAA----AAAGRHCPLRLAGQA 304
Query: 274 PEAALAWLVRPPRDLDEAVVEGEVVA-----------------QTVLPALRVLPVVGEAV 316
P A P E G A Q++ L V P G V
Sbjct: 305 PRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV 364
Query: 317 HD--ELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAA-GPRHLLPRPLLALGPRG 373
+ E V +R HL G+ R+G+ +R G R LG RG
Sbjct: 365 GEAREAVTTHERAHL------DREGEARARLGQAAAQMRREGWGAR-------AKLGGRG 411
Query: 374 PADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAPQRP 433
C G G + R R AA R L RA +GS R G A +
Sbjct: 412 V--CGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGR-- 467
Query: 434 VPPGPRR 440
VP G RR
Sbjct: 468 VPSGGRR 474
>gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo
sapiens]
Length = 594
Score = 44.3 bits (103), Expect = 2e-04
Identities = 125/487 (25%), Positives = 160/487 (32%), Gaps = 135/487 (27%)
Query: 44 GGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG-------GDGRWQRRQRGHG---- 92
GG+AG G G GC R + RG R G G W R++ HG
Sbjct: 33 GGQAGHPVVGDTGQ-FERGCARRHRSPRGHRHAVPGPRLQRALGGQAWAGRRQLHGFMLY 91
Query: 93 ------GRRG---LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIH 143
G RG + G G GG RLQ +VA G G G +DH+G +
Sbjct: 92 SGQQRDGHRGGHDVGGRGGGG---------RLQ------LVAGALGLGAGVLDHSGLRVA 136
Query: 144 VWPAGAQR----AAHGSQLVGE--RVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEAR 197
V A + A H + E RV L G G+P R V +G+ +LEA
Sbjct: 137 VGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPAR--------VAEGQDLLEAG 188
Query: 198 GLRHAAQVVG----GGGHLWQVRARGRQR-----------------AEPQLGLLLQVLRR 236
G A Q+ G + +V A G Q E Q LL+Q +
Sbjct: 189 GRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQALLVQAAQH 248
Query: 237 ----------------------VGWLAGRQVVGLKHLEALAAPQEAAVLEHVPAAWV-QR 273
+G G + GL +L + A AA H P Q
Sbjct: 249 CVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAA----AAAGRHCPLRLAGQA 304
Query: 274 PEAALAWLVRPPRDLDEAVVEGEVVA-----------------QTVLPALRVLPVVGEAV 316
P A P E G A Q++ L V P G V
Sbjct: 305 PRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV 364
Query: 317 HD--ELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAA-GPRHLLPRPLLALGPRG 373
+ E V +R HL G+ R+G+ +R G R LG RG
Sbjct: 365 GEAREAVTTHERAHL------DREGEARARLGQAAAQMRREGWGAR-------AKLGGRG 411
Query: 374 PADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAPQRP 433
C G G + R R AA R L RA +GS R G A +
Sbjct: 412 V--CGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGR-- 467
Query: 434 VPPGPRR 440
VP G RR
Sbjct: 468 VPSGGRR 474
>gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo
sapiens]
Length = 321
Score = 43.5 bits (101), Expect = 4e-04
Identities = 52/175 (29%), Positives = 71/175 (40%), Gaps = 20/175 (11%)
Query: 7 GGGRQDWEPGKASEVVGRRTR-GGVGSCGSVH-RHRVQGGGRAGERFAGGGG-----AAL 59
GGG + G+ + G ++R GGV S G R R Q AG + GGGG A
Sbjct: 146 GGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARA 205
Query: 60 AGGCLRG--RGAERGRRVREQGGDGRWQR-RQRGHGG-----RRGLNGHGDGGQRLARRV 111
G RG + RG++ GG+ ++ RQ+G G RRG GG+R
Sbjct: 206 VGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGER----- 260
Query: 112 AQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSG 166
++ +R AV A RV ++ QR S RVGSG
Sbjct: 261 CKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGSG 315
Score = 33.5 bits (75), Expect = 0.42
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 25 RTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRR-VREQGGDGR 83
+TRGG G R Q AG + GGG + G +R RG + + GG G+
Sbjct: 143 QTRGG----GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198
Query: 84 WQRRQRGHGG---------RRGLNGHGDGGQRLARRVAQR 114
++ R G RRG GG++ +++ Q+
Sbjct: 199 KPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQ 238
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 43.1 bits (100), Expect = 5e-04
Identities = 35/103 (33%), Positives = 38/103 (36%), Gaps = 12/103 (11%)
Query: 2 GGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61
GGG +G G + G S G GG GS GS GGG G GGG +
Sbjct: 521 GGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGS 580
Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104
G G G R GG G G G RG G GG
Sbjct: 581 GSSSG-----GYRGGSGGGGG-------GSSGGRGSGGGSSGG 611
Score = 38.5 bits (88), Expect = 0.013
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRG---GVGSCGSVHRHRVQGGGRAGERFAGGG---- 55
GG GGGR + G +S G + G G G GS GG R G GGG
Sbjct: 542 GGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGG 601
Query: 56 ---GAALAGGCLRGRGAERGRRVREQGG 80
G +GG + GRG+ G V+ GG
Sbjct: 602 RGSGGGSSGGSIGGRGSSSG-GVKSSGG 628
Score = 38.1 bits (87), Expect = 0.017
Identities = 42/144 (29%), Positives = 49/144 (34%), Gaps = 26/144 (18%)
Query: 2 GGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61
GGG GGG GG GS GS + GGG G GGGG G
Sbjct: 514 GGGSRGGGG-----------------GGYGSGGSSYG---SGGGSYGSGGGGGGGRGSYG 553
Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQ-RGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
G+ G GG G GG RG +G G GG R ++
Sbjct: 554 SGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSI 613
Query: 121 GAVVATRHGDGGGRVDHAGGAIHV 144
G G G V +GG+ V
Sbjct: 614 GG-----RGSSSGGVKSSGGSSSV 632
Score = 34.3 bits (77), Expect = 0.25
Identities = 37/107 (34%), Positives = 44/107 (41%), Gaps = 11/107 (10%)
Query: 2 GGGEW---GGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGG-GGA 57
GGG + GGG + G G R+ +G S+ +GGGR G F GG GG
Sbjct: 42 GGGRFSSCGGGGGSFGAGGG---FGSRSLVNLGGSKSISISVARGGGR-GSGFGGGYGGG 97
Query: 58 ALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104
GG G G G GG G + G GG G G G GG
Sbjct: 98 GFGGGGFGGGGFGGGG--IGGGGFGGFGSGGGGFGG-GGFGGGGYGG 141
Score = 32.0 bits (71), Expect = 1.2
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 20/98 (20%)
Query: 23 GRRTRGGV--GSCGSVHRHR------VQGGGRAGERFA---GGGGAALAGGCLRGR---- 67
G R+ GG GS G ++ R + G G RF+ GGGG+ AGG R
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVN 69
Query: 68 -GAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104
G + + G GR G GG G G G GG
Sbjct: 70 LGGSKSISISVARGGGRGS----GFGGGYGGGGFGGGG 103
Score = 30.0 bits (66), Expect = 4.6
Identities = 20/64 (31%), Positives = 23/64 (35%), Gaps = 3/64 (4%)
Query: 41 VQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGH 100
+ GGG G GGGG G G G GG G + +G G G
Sbjct: 512 ISGGGSRG---GGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS 568
Query: 101 GDGG 104
G GG
Sbjct: 569 GGGG 572
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 42.7 bits (99), Expect = 7e-04
Identities = 38/103 (36%), Positives = 42/103 (40%), Gaps = 16/103 (15%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERF--AGGGGAALA 60
GG GG E G + GV R +GGGR R+ AG GG
Sbjct: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGV------RREGARGGGRGRGRWKQAGRGG---- 71
Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103
G C RGRG RGR G GR + R R G GL G G G
Sbjct: 72 GVCGRGRGRGRGR----GRGRGRGRGRGRPPSGGSGLGGDGGG 110
Score = 33.1 bits (74), Expect = 0.55
Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 11/105 (10%)
Query: 43 GGGRAGERFA---GGGGAALAGGCLRG---RGAERGRRVREQGGDGRWQRRQRGHGGRRG 96
GG AG A GG G+ALA + G GA G R G GRW++ RG G
Sbjct: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGR-----GRGRWKQAGRGGGVCGR 76
Query: 97 LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141
G G G R R R + + G+ + G GG GGA
Sbjct: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
Score = 30.4 bits (67), Expect = 3.5
Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 7 GGGRQDW-EPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
G GR W + G+ V GR G G R R +G +G GG G GG
Sbjct: 58 GRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSG 117
Query: 66 GRGAER 71
G GA R
Sbjct: 118 GGGAPR 123
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 42.7 bits (99), Expect = 7e-04
Identities = 38/103 (36%), Positives = 42/103 (40%), Gaps = 16/103 (15%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERF--AGGGGAALA 60
GG GG E G + GV R +GGGR R+ AG GG
Sbjct: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGV------RREGARGGGRGRGRWKQAGRGG---- 71
Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103
G C RGRG RGR G GR + R R G GL G G G
Sbjct: 72 GVCGRGRGRGRGR----GRGRGRGRGRGRPPSGGSGLGGDGGG 110
Score = 33.1 bits (74), Expect = 0.55
Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 11/105 (10%)
Query: 43 GGGRAGERFA---GGGGAALAGGCLRG---RGAERGRRVREQGGDGRWQRRQRGHGGRRG 96
GG AG A GG G+ALA + G GA G R G GRW++ RG G
Sbjct: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGR-----GRGRWKQAGRGGGVCGR 76
Query: 97 LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141
G G G R R R + + G+ + G GG GGA
Sbjct: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
Score = 30.4 bits (67), Expect = 3.5
Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 7 GGGRQDW-EPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
G GR W + G+ V GR G G R R +G +G GG G GG
Sbjct: 58 GRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSG 117
Query: 66 GRGAER 71
G GA R
Sbjct: 118 GGGAPR 123
>gi|31542255 hypothetical protein LOC140706 [Homo sapiens]
Length = 433
Score = 42.7 bits (99), Expect = 7e-04
Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 6 WGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
WGGG + G R R G + GS R + G + ER GGGG GG
Sbjct: 207 WGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSG--SWERRHGGGG---GGGGAG 261
Query: 66 GRGAERGRRVREQGGDGRWQRRQRG 90
G RR GG G W+RR G
Sbjct: 262 KPGGSWERRQAGSGGGGSWERRHPG 286
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/108 (36%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 7 GGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRG 66
G GR PG A E T + S+ GGG A R GGGG +L R
Sbjct: 172 GAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLE----RQ 227
Query: 67 RGAER--GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVA 112
R R G R Q G W+RR HGG G G G G RR A
Sbjct: 228 RAGARASGSWERRQTFSGSWERR---HGGGGGGGGAGKPGGSWERRQA 272
Score = 35.0 bits (79), Expect = 0.14
Identities = 40/139 (28%), Positives = 53/139 (38%), Gaps = 21/139 (15%)
Query: 93 GRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDH-----AGGAIHVWPA 147
G G + GG RRV +RH + ++ R G GGG + GG++ A
Sbjct: 171 GGAGRDPGPPGGAPEKRRVGTAERRHTICSL-DWRMGWGGGAAEARAGGGGGGSLERQRA 229
Query: 148 GAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVG 207
GA RA+ + GS R HGG G G G + G Q
Sbjct: 230 GA-RASGSWERRQTFSGSWERRHGGGG--------------GGGGAGKPGGSWERRQAGS 274
Query: 208 GGGHLWQVRARGRQRAEPQ 226
GGG W+ R G +PQ
Sbjct: 275 GGGGSWERRHPGPNPLDPQ 293
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 37/191 (19%)
Query: 6 WGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
W G++D + + G +RG G + R Q AG AA G
Sbjct: 633 WRRGQKDAAAAEKAWATGATSRGSGGK-----QPRWQKPAAAGSE---SSAAAAVGQEAE 684
Query: 66 GRGAERGRRVREQGGDGR--------WQRR--------QRGHGGRRGLNGHGDGGQRLAR 109
R R RR + +G G+ WQRR RG GG + G GG + +R
Sbjct: 685 ARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKS---RGSGGAK-SR 740
Query: 110 RVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA-----IHVWPAGAQRAAHGSQLVGERVG 164
R A + HG GG + GGA AG Q+AA RV
Sbjct: 741 GSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVK 800
Query: 165 SGHRLHGGEGQ 175
S GG GQ
Sbjct: 801 S----RGGRGQ 807
Score = 33.9 bits (76), Expect = 0.32
Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 28/156 (17%)
Query: 7 GGGRQDWEPG-KASEVVGRRTRGGVGSC----GSVHRHRVQGGGRA--GERFAGGGGAAL 59
GG ++ G KA++ G ++R G G G R + G G++ G A+
Sbjct: 422 GGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASA 481
Query: 60 AGGCLRGRGAERGRRVREQGGDGRWQRRQRGH--GGRRGLNGHGDGGQRLARRV------ 111
AG RG G ++ G W+R Q+ G + G G++ RR
Sbjct: 482 AGTKSRGGG------LKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAG 535
Query: 112 -------AQRLQRHAVGAVVATRHGDGGGRVDHAGG 140
++ QR A AT HG GG + GG
Sbjct: 536 AKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGG 571
Score = 32.3 bits (72), Expect = 0.93
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 11/129 (8%)
Query: 10 RQDWEPGKA-SEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERF-AGGGGAALAGGCLRGR 67
R D + G+ + G ++RGG + H + R G++ A G A AG RGR
Sbjct: 469 RGDKKQGRQKASAAGTKSRGG-----GLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGR 523
Query: 68 GAERGRRVREQGGDGRW---QRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVV 124
R ++ G R + RQR G HG GG + +R R G
Sbjct: 524 KQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQ-WGQTA 582
Query: 125 ATRHGDGGG 133
A GGG
Sbjct: 583 AAAKTRGGG 591
Score = 31.6 bits (70), Expect = 1.6
Identities = 29/131 (22%), Positives = 53/131 (40%), Gaps = 9/131 (6%)
Query: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
+G GG ++ G+ + + G + RG + + + +G G G + GG
Sbjct: 263 VGKSRGGGDKKLRRQGQNAALAGAKRRG---AATAGEKPAAKGRGGRGPKSLGGQNPRW- 318
Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120
GRG ++ RR ++ +RG GG++ G ++ RR ++ +R
Sbjct: 319 -----GRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKA 373
Query: 121 GAVVATRHGDG 131
A A G G
Sbjct: 374 SAAGAKSRGGG 384
Score = 30.4 bits (67), Expect = 3.5
Identities = 52/206 (25%), Positives = 78/206 (37%), Gaps = 46/206 (22%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGA-ALAG 61
G + GGG Q + + VVG ++R G + R Q AG + GGG L
Sbjct: 339 GTKRGGGGQ-----QKAAVVGVKSRKKQRRRGK--KPRRQKASAAGAKSRGGGDKKGLRE 391
Query: 62 GCLRGRG------------AERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG-DGGQRLA 108
RG G A++ + +GG + RR RG + G GG +
Sbjct: 392 AKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRR-RGPKAAKSRGGKSRSGGGKKP 450
Query: 109 RRVAQRLQRHAVGAVVATRHGD----------------GGGRVDHAGGAIHVWPAGAQRA 152
RR Q+ ++ A A +R GD GGG H+G ++W G +
Sbjct: 451 RRRGQKARQKAAEAGAESR-GDKKQGRQKASAAGTKSRGGGLKSHSGK--NLWRRGQK-- 505
Query: 153 AHGSQLVGERVGSGHRLHGGEGQPPR 178
++ GE+ + G QP R
Sbjct: 506 ---AEAAGEKATAAGAKSRGRKQPRR 528
Score = 30.0 bits (66), Expect = 4.6
Identities = 50/210 (23%), Positives = 74/210 (35%), Gaps = 25/210 (11%)
Query: 25 RTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVR---EQGGD 81
++R G G +HR G + GGG RG+ A G + R +GG
Sbjct: 211 KSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGG 270
Query: 82 GRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141
+ RRQ GQ A A+R G A + G GG GG
Sbjct: 271 DKKLRRQ---------------GQNAALAGAKRRGAATAGEKPAAK-GRGGRGPKSLGGQ 314
Query: 142 IHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLD---GEGVLEARG 198
W G ++ Q + +G + GG GQ +V + G+ +
Sbjct: 315 NPRWGRGGKKPRRRGQKATKAAAAGTK-RGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKA 373
Query: 199 LRHAAQVVGGGGH--LWQVRARGRQRAEPQ 226
A+ GGG L + + RG R +P+
Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPR 403
Score = 30.0 bits (66), Expect = 4.6
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 7/89 (7%)
Query: 2 GGG---EWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGG--RAGERF--AGG 54
GGG GG + G A G++ G + R GG R+GE+ AGG
Sbjct: 726 GGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGG 785
Query: 55 GGAALAGGCLRGRGAERGRRVREQGGDGR 83
AA AGG R RG R ++ G+
Sbjct: 786 QKAAAAGGKKPPRVKSRGGRGQKAAAGGK 814
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 9/147 (6%)
Query: 29 GVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG----GCLRGRGAERGRRVREQGGDGRW 84
G G +H+ G +G G G +G G G+ + RG R R G
Sbjct: 224 GSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSS-RGERHRSSSGSSS- 281
Query: 85 QRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHV 144
Q G G R+ L GHG G R + RH G+ ++ HG G ++ H
Sbjct: 282 SYGQHGSGSRQSL-GHGRQGS--GSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHY 338
Query: 145 WPAGAQRAAHGSQLVGERVGSGHRLHG 171
Q + G G SG+ HG
Sbjct: 339 ESGSGQTSGFGQHESGSGQSSGYSKHG 365
Score = 38.5 bits (88), Expect = 0.013
Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%)
Query: 3 GGEWGGGRQDWEPGK--ASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
G W R +E G +S + R +R G S H G+ + G ++
Sbjct: 1030 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1089
Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G G G+ + G Q G G Q G G G G + R + RH
Sbjct: 1090 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144
Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177
G+ ++ G G + + G H + Q +++ G SG+ HG GQ
Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204
Query: 178 R 178
R
Sbjct: 1205 R 1205
Score = 38.5 bits (88), Expect = 0.013
Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%)
Query: 3 GGEWGGGRQDWEPGKA--SEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
G W R +E G + S + R +R G S H G+ + G ++
Sbjct: 1500 GSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1559
Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G G G+ + G Q G G Q G G G G + R + RH
Sbjct: 1560 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614
Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177
G+ ++ G G + + G H + Q +++ G SG+ HG GQ
Sbjct: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1674
Query: 178 R 178
R
Sbjct: 1675 R 1675
Score = 38.5 bits (88), Expect = 0.013
Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%)
Query: 3 GGEWGGGRQDWEPGK--ASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
G W R +E G +S + R +R G S H G+ + G ++
Sbjct: 1970 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029
Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G G G+ + G Q G G Q G G G G + R + RH
Sbjct: 2030 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084
Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177
G+ ++ G G + + G H + Q +++ G SG+ HG GQ
Sbjct: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2144
Query: 178 R 178
R
Sbjct: 2145 R 2145
Score = 38.5 bits (88), Expect = 0.013
Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%)
Query: 3 GGEWGGGRQDWEPGK--ASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
G W R +E G +S + R +R G S H G+ + G ++
Sbjct: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 2499
Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G G G+ + G Q G G Q G G G G + R + RH
Sbjct: 2500 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554
Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177
G+ ++ G G + + G H + Q +++ G SG+ HG GQ
Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614
Query: 178 R 178
R
Sbjct: 2615 R 2615
Score = 35.8 bits (81), Expect = 0.084
Identities = 41/178 (23%), Positives = 59/178 (33%), Gaps = 6/178 (3%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
G G G+ G++S G R GS S +H G ++ G G+ +
Sbjct: 486 GHSSGHGQHGSRSGQSSR--GERQGSSAGSSSSYGQHG-SGSRQSLGHSRHGSGSGQSPS 542
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQR--LQRHAV 120
RGR R+ G G R G +GH G R Q +H
Sbjct: 543 PSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGS 602
Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
+ ++ HG G + Q ++HG G S + G G GQ P
Sbjct: 603 SSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP 660
Score = 35.0 bits (79), Expect = 0.14
Identities = 42/165 (25%), Positives = 53/165 (32%), Gaps = 33/165 (20%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
G G G + G++S + G S H R G GER G++
Sbjct: 2102 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-SGQSSRGERHGSSSGSS---- 2156
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122
R + G R+ G GR Q GH RG +G G G H
Sbjct: 2157 ---SRYGQHGSGSRQSSGHGR-QGSGSGHSPSRGRHGSGSG----------HSSSHG--- 2199
Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGH 167
+HG G GR G R+ H S GSGH
Sbjct: 2200 ----QHGSGSGRSSSRG-------PYESRSGHSSVFGQHESGSGH 2233
Score = 34.7 bits (78), Expect = 0.19
Identities = 33/147 (22%), Positives = 52/147 (35%), Gaps = 7/147 (4%)
Query: 35 SVHRHRVQGGGRA---GERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGH 91
S + HR G ++ G AG G + G G G+ + G W H
Sbjct: 1334 SSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR--HGSGSGHSSSYGQHGSGSGWSSSSGRH 1391
Query: 92 GGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQR 151
G G + G G + + +H G+ ++ + G R + +
Sbjct: 1392 GSGSGQSS-GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450
Query: 152 AAHGSQLVGERVGSGHRLHG-GEGQPP 177
+++G G R GH HG G GQ P
Sbjct: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQSP 1477
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/165 (22%), Positives = 58/165 (35%), Gaps = 16/165 (9%)
Query: 26 TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQ 85
T G SCG +H G + G G + +G +G G+ + ++G R
Sbjct: 1552 TSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1608
Query: 86 RRQRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGG 133
HG GR +G G G + + +H G+ ++ +G G
Sbjct: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1668
Query: 134 RVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
R + + + +G G R SGH G G GQ P
Sbjct: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSP 1713
Score = 34.7 bits (78), Expect = 0.19
Identities = 33/150 (22%), Positives = 50/150 (33%), Gaps = 5/150 (3%)
Query: 32 SCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGR---GAERGRRVREQGGDGRWQRRQ 88
S G H G G + G G+ RGR G+ + G W
Sbjct: 1799 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 1858
Query: 89 RGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAG 148
HG G + G G + + +H G+ ++ + G R + +
Sbjct: 1859 GRHGSGSGQSS-GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917
Query: 149 AQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
+++G G R GH HG G GQ P
Sbjct: 1918 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1947
Score = 34.7 bits (78), Expect = 0.19
Identities = 33/150 (22%), Positives = 50/150 (33%), Gaps = 5/150 (3%)
Query: 32 SCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGR---GAERGRRVREQGGDGRWQRRQ 88
S G H G G + G G+ RGR G+ + G W
Sbjct: 2269 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 2328
Query: 89 RGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAG 148
HG G + G G + + +H G+ ++ + G R + +
Sbjct: 2329 GRHGSGSGQSS-GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 2387
Query: 149 AQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
+++G G R GH HG G GQ P
Sbjct: 2388 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 2417
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/165 (22%), Positives = 58/165 (35%), Gaps = 16/165 (9%)
Query: 26 TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQ 85
T G SCG +H G + G G + +G +G G+ + ++G R
Sbjct: 2492 TSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 2548
Query: 86 RRQRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGG 133
HG GR +G G G + + +H G+ ++ +G G
Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2608
Query: 134 RVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
R + + + +G G R SGH G G GQ P
Sbjct: 2609 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
Score = 34.7 bits (78), Expect = 0.19
Identities = 45/202 (22%), Positives = 63/202 (31%), Gaps = 26/202 (12%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
G G G + G++S + G S H R G GER G++ G
Sbjct: 2572 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-SGQSSRGERHGSSSGSSSHYG 2630
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQR-----GHGGRRGLNGHGDGGQRLARRVAQRLQR 117
+ R+ G G+ R R GH G +G G G RL
Sbjct: 2631 QHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGH 2690
Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAG-------------------AQRAAHGSQL 158
+V + G H G+ H G Q +++G +
Sbjct: 2691 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG 2750
Query: 159 VGERVGSGHRLHG-GEGQPPRH 179
G SG+ HG G GQ H
Sbjct: 2751 SGSSQSSGYGRHGAGSGQSLSH 2772
Score = 34.3 bits (77), Expect = 0.25
Identities = 41/175 (23%), Positives = 59/175 (33%), Gaps = 15/175 (8%)
Query: 9 GRQDWEPGKASEVVGRRTRGGVGSCGSVHR---HRVQGGGRAGERFAGGGGAALAG--GC 63
GR G++S + G S H H G GR G +G G + G G
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHG---SGSGQSPGHGQRGS 898
Query: 64 LRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAV 123
G+ GR G R G G G GQ + +H G+
Sbjct: 899 GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQ------SSGYTQHGSGSG 952
Query: 124 VATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
++ + G R + + + +++G G R GH HG G GQ P
Sbjct: 953 HSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1007
Score = 33.5 bits (75), Expect = 0.42
Identities = 43/179 (24%), Positives = 61/179 (34%), Gaps = 10/179 (5%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA-----GERFAGGGGA 57
G G + G S R G GS G H +G G G +G G +
Sbjct: 1563 GASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1621
Query: 58 ALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQR 117
+ +G G G G E Q G G +G+G G R + + R +R
Sbjct: 1622 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS-SGYGQHGSRSGQ--SSRGER 1678
Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQ 175
H + ++R+G G + G Q + G G S H HG G G+
Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR 1737
Score = 32.7 bits (73), Expect = 0.71
Identities = 41/159 (25%), Positives = 58/159 (36%), Gaps = 35/159 (22%)
Query: 23 GRRTRGGVGSCGSVHRHRVQGGGRA---GERFAGGGGAALAGGCLRGRGAERGRRVREQG 79
G+ + G S G H R G G++ G+ G G ++ +G + G G G E
Sbjct: 414 GQHSSGSGQSPG--HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESS 471
Query: 80 GDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAG 139
+ Q G G +GHG G R + + R +R A ++ +G
Sbjct: 472 SEHSSGYTQHGSGSGHS-SGHGQHGSRSGQ--SSRGERQGSSAGSSSSYGQ--------- 519
Query: 140 GAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
HGS G R GH HG G GQ P
Sbjct: 520 --------------HGS---GSRQSLGHSRHGSGSGQSP 541
Score = 32.7 bits (73), Expect = 0.71
Identities = 36/165 (21%), Positives = 57/165 (34%), Gaps = 16/165 (9%)
Query: 26 TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQ 85
T G SCG +H G + G G + +G +G G+ + ++G R
Sbjct: 1082 TSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1138
Query: 86 RRQRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGG 133
HG GR +G G G + + +H G+ ++ +G G
Sbjct: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1198
Query: 134 RVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
R + + + +G G R SGH G G G P
Sbjct: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSP 1243
Score = 32.3 bits (72), Expect = 0.93
Identities = 42/179 (23%), Positives = 60/179 (33%), Gaps = 10/179 (5%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA-----GERFAGGGGA 57
G G + G S R G GS G H +G G G +G G +
Sbjct: 2033 GASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRS 2091
Query: 58 ALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQR 117
+ +G G G G E Q G G +G+G G R + + R +R
Sbjct: 2092 SSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS-SGYGQHGSRSGQ--SSRGER 2148
Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQ 175
H + ++R+G G + G + G G S H HG G G+
Sbjct: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGR 2207
Score = 32.0 bits (71), Expect = 1.2
Identities = 35/155 (22%), Positives = 49/155 (31%), Gaps = 15/155 (9%)
Query: 29 GVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQ 88
G G S H G +G G G + +G G G+ R+ G R
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQS-SGYSQHGSGSSHSSGYRKHGSRSGQSSRS 739
Query: 89 RGHGGRRGLNG----HGDGGQRLARRVAQ--------RLQRHAVGAVVATRHGDGGGRVD 136
HG GL+ HG G + + Q RH + ++ HG G
Sbjct: 740 EQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTS 799
Query: 137 HAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG 171
+ H Q + G G G G+ HG
Sbjct: 800 CSSSCGHYESGSGQASGFGQHESGS--GQGYSQHG 832
Score = 31.6 bits (70), Expect = 1.6
Identities = 35/163 (21%), Positives = 56/163 (34%), Gaps = 16/163 (9%)
Query: 28 GGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRR 87
G SCG +H G + G G + +G +G G+ + ++G R
Sbjct: 2024 GQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2080
Query: 88 QRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRV 135
HG GR +G G G + + +H G+ ++ +G G R
Sbjct: 2081 YGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2140
Query: 136 DHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177
+ + + +G G R SGH G G G P
Sbjct: 2141 GQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSP 2183
Score = 31.2 bits (69), Expect = 2.1
Identities = 40/183 (21%), Positives = 61/183 (33%), Gaps = 32/183 (17%)
Query: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-- 61
G+ G + +S G+ G S G H + G G + R G G +
Sbjct: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSG--HGRQGSGSGHSPSRGRHGSGLGHSSSH 1258
Query: 62 ---GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G GR + RG G + + + G G + HG G +
Sbjct: 1259 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ-------- 1310
Query: 119 AVGAVVATRHGDGGGR---VDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEG 174
+HG G+ D G + Q +++G + G SG+ HG G G
Sbjct: 1311 -------GQHGSTSGQSSTFDQEGSST------GQSSSYGHRGSGSSQSSGYGRHGAGSG 1357
Query: 175 QPP 177
Q P
Sbjct: 1358 QSP 1360
Score = 30.4 bits (67), Expect = 3.5
Identities = 44/190 (23%), Positives = 60/190 (31%), Gaps = 20/190 (10%)
Query: 2 GGGEWGGGR-QDWEPGKASEVVGRRTRGGVGSCGSVH-----RHRVQGGGRAGERFAGGG 55
G G+ G G Q G+ GR + G GS + H +G G G
Sbjct: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG 484
Query: 56 GAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHG-GRRGLNGHGDGGQRLARRVAQR 114
+G G + + R QG HG G R GH G + +
Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPS 544
Query: 115 LQRHAVGAVVATR---HGDGGGRVD----------HAGGAIHVWPAGAQRAAHGSQLVGE 161
RH G+ ++ HG G GR H+ G H Q + +G
Sbjct: 545 RGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSS 604
Query: 162 RVGSGHRLHG 171
S H HG
Sbjct: 605 GHSSTHGQHG 614
Score = 30.0 bits (66), Expect = 4.6
Identities = 39/183 (21%), Positives = 60/183 (32%), Gaps = 32/183 (17%)
Query: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-- 61
G+ G + ++S G+ G S G H + G G++ R G G +
Sbjct: 1671 GQSSRGERHGSSSRSSSRYGQHGSGSRQSSG--HGRQGSGSGQSPSRGRHGSGLGHSSSH 1728
Query: 62 ---GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G GR + RG G + + + G G + HG G +
Sbjct: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ-------- 1780
Query: 119 AVGAVVATRHGDGGGR---VDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEG 174
+HG G+ D G + Q ++HG G S + G G G
Sbjct: 1781 -------GQHGSTSGQSSTFDQEGSST------GQSSSHGQHGSGSSQSSSYGQQGSGSG 1827
Query: 175 QPP 177
Q P
Sbjct: 1828 QSP 1830
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/184 (27%), Positives = 65/184 (35%), Gaps = 40/184 (21%)
Query: 8 GGRQDWEPGKASEV-----------VGRRTRGGVGSC----GSVHRHRVQGGGRAGERFA 52
GG++D+E A ++ GR +RGG G GS + G R G +
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519
Query: 53 GGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVA 112
GGG+ GG G G G G G +GG G G GG
Sbjct: 520 YGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG-------- 571
Query: 113 QRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERV-GSGHRLHG 171
G +R G GG H GG +G + GS GE GSG G
Sbjct: 572 -------YGGGSGSRGGSGG---SHGGG------SGFGGESGGSYGGGEEASGSGGGYGG 615
Query: 172 GEGQ 175
G G+
Sbjct: 616 GSGK 619
Score = 40.8 bits (94), Expect = 0.003
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 23/152 (15%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
GG +GGG G G +RGG G GS GGG G + GG G +GG
Sbjct: 494 GGSYGGGGSGGGYGG-----GSGSRGGSG--GSYGGGSGSGGGSGG-GYGGGSGGGHSGG 545
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122
G G G GG G G+GG G G G GG H G+
Sbjct: 546 --SGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRG-GSGGS------------HGGGS 590
Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAH 154
G G + A G+ + G+ +++H
Sbjct: 591 GFGGESGGSYGGGEEASGSGGGYGGGSGKSSH 622
Score = 35.8 bits (81), Expect = 0.084
Identities = 32/102 (31%), Positives = 33/102 (32%), Gaps = 10/102 (9%)
Query: 2 GGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61
GGG G G S G G G G H GG G GGG+ G
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGG 566
Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103
G G G G R GG G HGG G G G
Sbjct: 567 GSGGGYGGGSGSR----GGSG------GSHGGGSGFGGESGG 598
Score = 35.4 bits (80), Expect = 0.11
Identities = 30/85 (35%), Positives = 34/85 (40%), Gaps = 8/85 (9%)
Query: 28 GGVGSCGSVH----RHRVQGGGRAGERF--AGGGGAALAGGCLRGRGAERGRRVREQGGD 81
GG+GS GS+ R GGG G RF + G G + C RG G G G
Sbjct: 20 GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
Query: 82 GRWQRRQRG--HGGRRGLNGHGDGG 104
G G GG RG G GG
Sbjct: 80 GFSASSLGGGFGGGSRGFGGASGGG 104
Score = 30.8 bits (68), Expect = 2.7
Identities = 33/110 (30%), Positives = 36/110 (32%), Gaps = 31/110 (28%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA-- 60
GG GGGR G G CG GGG G + GG G +
Sbjct: 39 GGGGGGGRFSSSSGYGG--------GSSRVCGR------GGGGSFGYSYGGGSGGGFSAS 84
Query: 61 ------GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104
GG RG G G GG G GG G +G G GG
Sbjct: 85 SLGGGFGGGSRGFGGASGGGYSSSGGFG---------GGFGGGSGGGFGG 125
Score = 29.6 bits (65), Expect = 6.0
Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 20/80 (25%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
GG +GGG + + G + GG S G GGG F GG G GG
Sbjct: 87 GGGFGGGSRGF---------GGASGGGYSSSGGF------GGG-----FGGGSGGGFGGG 126
Query: 63 CLRGRGAERGRRVREQGGDG 82
G G G GGDG
Sbjct: 127 YGSGFGGFGGFGGGAGGGDG 146
>gi|239749709 PREDICTED: hypothetical protein [Homo sapiens]
Length = 178
Score = 40.8 bits (94), Expect = 0.003
Identities = 44/154 (28%), Positives = 54/154 (35%), Gaps = 16/154 (10%)
Query: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQG-------GGRAGERFAGGGGAALAGGCLRGRG 68
G+AS G R R G+G G R R +G G R GG A A G
Sbjct: 2 GEASSAPGGRGRSGLGGSGGAPRVRGRGTAVGVGIGVRVWRSRRAEGGGAEAAAARTAGG 61
Query: 69 AERGRRVREQGGDGRWQRRQR-GHG----GRR----GLNGHGDGGQRLARRVAQRLQRHA 119
R +R D R +R HG G R G G G Q R+ ++ H
Sbjct: 62 EPRAQRQAGSQADEEGGRPERVNHGQVPQGERLRAMAKGGVGKGSQGAERQASRPHAEHR 121
Query: 120 VGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAA 153
+G TR G AG A P G + A
Sbjct: 122 LGLSHLTRAAGAGAARRRAGAARTRSPKGCRAGA 155
Score = 31.2 bits (69), Expect = 2.1
Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 40/141 (28%)
Query: 44 GGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103
GGR G GGA +RGRG G + G W+ R+ GG G
Sbjct: 9 GGRGRSGLGGSGGAPR----VRGRGTAVGVGI----GVRVWRSRRAEGGGAEAAAARTAG 60
Query: 104 GQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERV 163
G+ A+R A G + D GG +R HG GER+
Sbjct: 61 GEPRAQRQA-------------------GSQADEEGGR-------PERVNHGQVPQGERL 94
Query: 164 ------GSGHRLHGGEGQPPR 178
G G G E Q R
Sbjct: 95 RAMAKGGVGKGSQGAERQASR 115
>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
sapiens]
Length = 351
Score = 40.4 bits (93), Expect = 0.003
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 24/167 (14%)
Query: 26 TRGGVGSCGSVHRHRVQGGG-----RAGERFA---GGGGAALAGGCLRGRGAERGRRVRE 77
+R G C S ++R GGG R G++ A GGGG G G GA++ R+ R
Sbjct: 124 SRAGSRVCRSRPQNR--GGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRR 181
Query: 78 QGGDGRWQRRQRGHGGRR-----GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGG 132
+G R GG++ G GG++ A ++ +R G A G G
Sbjct: 182 RG------ERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRR-GQKAAKSRGGGD 234
Query: 133 GRVDHAGGAI-HVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPR 178
+++ A+ V G ++ G + ER G + GG G+ P+
Sbjct: 235 KKLERQKAALTGVKSRGDKKPLRGGKKQRER-GQNTKSRGGGGEKPQ 280
>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens]
Length = 1555
Score = 40.4 bits (93), Expect = 0.003
Identities = 63/234 (26%), Positives = 81/234 (34%), Gaps = 39/234 (16%)
Query: 4 GEWGGG---RQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60
G+ GGG R + G+ R G G G+ R G G+ AGGGG
Sbjct: 796 GQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFE----GPIGQ--AGGGGFRFE 849
Query: 61 GGC-LRGRGAERGRRVREQGGDGRWQRRQRGHGGRR--GLNGHGDGGQRLARRVAQRLQR 117
G LR G+ G R GG R GH G+ GL G GQ + +
Sbjct: 850 GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRG 909
Query: 118 HAVGAV----------VATR----HGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGER- 162
VG + A R HG GG + G + HG + G R
Sbjct: 910 QPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRF 969
Query: 163 ------VGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGG 210
+G R G GQP + F +G V + G+R V GGG
Sbjct: 970 EGQHNQLGGNLRFEGPHGQPGVGIRF------EGPLVQQGGGMRFEGPSVPGGG 1017
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 40.0 bits (92), Expect = 0.004
Identities = 56/199 (28%), Positives = 68/199 (34%), Gaps = 44/199 (22%)
Query: 19 SEVVGRRTRG------GVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERG 72
S GRR G G G H H G+AG + E G
Sbjct: 1945 SRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYP-----------------ESG 1987
Query: 73 RRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGG 132
V E+ G Q R G +GHG QR +R +R H + + G G
Sbjct: 1988 SSVHERHGTTHGQTADTT---RHGHSGHGQSTQRGSRTTGRRASGH---SEYSDSEGHSG 2041
Query: 133 GRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEG 192
H+G A AG+Q GS V ER G+ HG G RH G G
Sbjct: 2042 VSHTHSGHA--HGQAGSQHGESGSS-VHERHGT---THGQTGDTTRH-------AHSGHG 2088
Query: 193 VLEARGLRHAAQVVGGGGH 211
RG R A + G GH
Sbjct: 2089 QSTQRGSRTAGR--RGSGH 2105
Score = 32.3 bits (72), Expect = 0.93
Identities = 48/205 (23%), Positives = 66/205 (32%), Gaps = 47/205 (22%)
Query: 9 GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA---GERFAGGGGAA------- 58
G+ + G++ V R G G RH G G++ G R AG G+
Sbjct: 2052 GQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDS 2111
Query: 59 -LAGGCLRGRGAERGRRVREQGGD------GRWQ--RRQRGHGGRRGLNGHGDGGQRLAR 109
+ G + R Q G+ GR Q G R G +GHG Q +R
Sbjct: 2112 EVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSR 2171
Query: 110 RVAQRLQRHA------------------VGAVVATRHGDGGGRVDHAGGAIHVWPAGAQR 151
++ H+ + +RHG G G H R
Sbjct: 2172 TTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTR 2231
Query: 152 AAH---------GSQLVGERVGSGH 167
AH GS+ G R GSGH
Sbjct: 2232 HAHYGYGQSTQRGSRTTGRR-GSGH 2255
Score = 29.3 bits (64), Expect = 7.9
Identities = 31/105 (29%), Positives = 35/105 (33%), Gaps = 7/105 (6%)
Query: 67 RGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARR---VAQRLQRHAVG-A 122
R A G Q G RR GH GH QR R Q +H +
Sbjct: 1779 RHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESES 1838
Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGH 167
+V RHG G+ G H Q GS G R SGH
Sbjct: 1839 IVDERHGTTHGQTGDTSG--HSQSGHGQSTQSGSSTTGRR-RSGH 1880
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 12/102 (11%)
Query: 3 GGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62
GG +GGG ++ G+ GR GG G G R GG F G GG G
Sbjct: 227 GGNFGGGGGNF--GRGGNFGGR---GGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGP 281
Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104
RG G GG G + + G+GG G +G+ +GG
Sbjct: 282 GYSSRGGYGG------GGPG-YGNQGGGYGGGGGYDGYNEGG 316
Score = 36.2 bits (82), Expect = 0.065
Identities = 41/124 (33%), Positives = 48/124 (38%), Gaps = 30/124 (24%)
Query: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA-----GERFAGGGGAALAGGCLRGRGAE 70
G EV ++ + S GS R +GGG G F GGGG GG GRG
Sbjct: 193 GHNCEVKKALSKQEMQSAGS---QRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGG- 248
Query: 71 RGRRVREQGGDGRWQRRQRGHGGRRGLNGH-GDGGQRLARRVAQRLQRHAVGAVVATRHG 129
GG G R G GG G NG GDGG + G ++R G
Sbjct: 249 -------YGGGGGGSRGSYG-GGDGGYNGFGGDGG------------NYGGGPGYSSRGG 288
Query: 130 DGGG 133
GGG
Sbjct: 289 YGGG 292
Score = 30.4 bits (67), Expect = 3.5
Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 9 GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRG 68
G Q G + +GR G G G GGR G GGG GG G G
Sbjct: 211 GSQRGRGGGSGNFMGRG--GNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGG---GDG 265
Query: 69 AERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103
G GGDG G+ R G G G G
Sbjct: 266 GYNG-----FGGDGGNYGGGPGYSSRGGYGGGGPG 295
>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
sapiens]
Length = 451
Score = 40.0 bits (92), Expect = 0.004
Identities = 54/172 (31%), Positives = 63/172 (36%), Gaps = 20/172 (11%)
Query: 2 GGGEWGGGRQDWEPGKASEV-VGRRTRGGVGSCGSVHRHRV-QGGGRAGERFAGGGGAAL 59
GGG+W GG E GKA GR GG G G H V QG AG +A G A
Sbjct: 80 GGGDWAGGPH-LEHGKAGGGGTGRADDGGGG--GGFHARLVHQGAAHAGAAWAQGSTAHH 136
Query: 60 AGGCLR-GRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118
G + GA G + + G + G GG G+ G GG A H
Sbjct: 137 LGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGH 196
Query: 119 AVGAVVAT-----RHGDGGGRVDHAGG----AIHVWPAGAQRAAHGSQLVGE 161
+ HG G HAGG A H+ P A G VGE
Sbjct: 197 EAQLEPSPPPHLGAHGHAHGHA-HAGGLHAAAAHLHPG----AGGGGSSVGE 243
>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 39.7 bits (91), Expect = 0.006
Identities = 59/194 (30%), Positives = 70/194 (36%), Gaps = 26/194 (13%)
Query: 43 GGGRAGER------FAGGGGAAL--AGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGR 94
GGGR R F GG L G LRG G RG +R Q R + R G G
Sbjct: 112 GGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQ----RVRSRLAGLGAP 167
Query: 95 RG--LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRA 152
RG G GGQ A+RL H G GGG + GG P A++
Sbjct: 168 RGGAAAPRGWGGQG-----AERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQP 222
Query: 153 AHGSQLVGER--VGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGG 210
G +GS R H G RH R V + R AA V
Sbjct: 223 PSGRPRPRRTRLLGSAER-HTGRAALARHGQLSRPHA----AVRNSSRGRGAATSVSAAA 277
Query: 211 HLWQVRARGRQRAE 224
+ ARG +RA+
Sbjct: 278 RPTRGGARGHRRAD 291
>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 39.7 bits (91), Expect = 0.006
Identities = 59/194 (30%), Positives = 70/194 (36%), Gaps = 26/194 (13%)
Query: 43 GGGRAGER------FAGGGGAAL--AGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGR 94
GGGR R F GG L G LRG G RG +R Q R + R G G
Sbjct: 112 GGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQ----RVRSRLAGLGAP 167
Query: 95 RG--LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRA 152
RG G GGQ A+RL H G GGG + GG P A++
Sbjct: 168 RGGAAAPRGWGGQG-----AERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQP 222
Query: 153 AHGSQLVGER--VGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGG 210
G +GS R H G RH R V + R AA V
Sbjct: 223 PSGRPRPRRTRLLGSAER-HTGRAALARHGQLSRPHA----AVRNSSRGRGAATSVSAAA 277
Query: 211 HLWQVRARGRQRAE 224
+ ARG +RA+
Sbjct: 278 RPTRGGARGHRRAD 291
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,689,535
Number of Sequences: 37866
Number of extensions: 1223621
Number of successful extensions: 6966
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 5505
Number of HSP's gapped (non-prelim): 1085
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.