Guide to the Human Genome
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Search of human proteins with 116734706

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116734706 interferon regulatory factor 2 binding protein 2
isoform B [Homo sapiens]
         (571 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116734706 interferon regulatory factor 2 binding protein 2 is...  1165   0.0  
gi|116734704 interferon regulatory factor 2 binding protein 2 is...  1155   0.0  
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]         300   3e-81
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho...   192   5e-49
gi|150170670 piccolo isoform 2 [Homo sapiens]                          62   1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          62   1e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni...    61   3e-09
gi|33286436 gametogenetin [Homo sapiens]                               60   7e-09
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       58   2e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       58   2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   5e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   4e-07
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]            54   5e-07
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]            54   5e-07
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]             54   5e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    53   7e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is...    51   3e-06
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             50   4e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         50   4e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  50   6e-06
gi|54860079 nadrin isoform 1 [Homo sapiens]                            50   6e-06
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  50   7e-06
gi|217416343 fibrosin-like 1 [Homo sapiens]                            49   1e-05
gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo ...    49   2e-05
gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo ...    49   2e-05
gi|239508758 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|221139926 NHS-like 1 [Homo sapiens]                                 48   2e-05
gi|239754516 PREDICTED: hypothetical protein [Homo sapiens]            48   2e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       48   2e-05
gi|18959210 WIRE protein [Homo sapiens]                                48   2e-05

>gi|116734706 interferon regulatory factor 2 binding protein 2
           isoform B [Homo sapiens]
          Length = 571

 Score = 1165 bits (3014), Expect = 0.0
 Identities = 571/571 (100%), Positives = 571/571 (100%)

Query: 1   MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60
           MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK
Sbjct: 1   MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60

Query: 61  RAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLA 120
           RAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLA
Sbjct: 61  RAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLA 120

Query: 121 AAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRR 180
           AAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRR
Sbjct: 121 AAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRR 180

Query: 181 GHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPAS 240
           GHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPAS
Sbjct: 181 GHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPAS 240

Query: 241 VSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN 300
           VSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN
Sbjct: 241 VSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN 300

Query: 301 RPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEA 360
           RPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEA
Sbjct: 301 RPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEA 360

Query: 361 QPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAG 420
           QPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAG
Sbjct: 361 QPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAG 420

Query: 421 GSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDS 480
           GSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDS
Sbjct: 421 GSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDS 480

Query: 481 SLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCP 540
           SLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCP
Sbjct: 481 SLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCP 540

Query: 541 LVGSNVPWAFMQGEIATILAGDVKVKKERDS 571
           LVGSNVPWAFMQGEIATILAGDVKVKKERDS
Sbjct: 541 LVGSNVPWAFMQGEIATILAGDVKVKKERDS 571


>gi|116734704 interferon regulatory factor 2 binding protein 2
           isoform A [Homo sapiens]
          Length = 587

 Score = 1155 bits (2987), Expect = 0.0
 Identities = 571/587 (97%), Positives = 571/587 (97%), Gaps = 16/587 (2%)

Query: 1   MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60
           MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK
Sbjct: 1   MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60

Query: 61  RAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLA 120
           RAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLA
Sbjct: 61  RAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLA 120

Query: 121 AAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRR 180
           AAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRR
Sbjct: 121 AAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRR 180

Query: 181 GHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPAS 240
           GHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPAS
Sbjct: 181 GHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPAS 240

Query: 241 VSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN 300
           VSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN
Sbjct: 241 VSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN 300

Query: 301 RPKTVRDTLLALHQHGHSGPFESKFKKEPALT----------------AVARTARKRKPS 344
           RPKTVRDTLLALHQHGHSGPFESKFKKEPALT                AVARTARKRKPS
Sbjct: 301 RPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPS 360

Query: 345 PEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQN 404
           PEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQN
Sbjct: 361 PEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQN 420

Query: 405 GQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAG 464
           GQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAG
Sbjct: 421 GQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAG 480

Query: 465 NTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQ 524
           NTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQ
Sbjct: 481 NTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQ 540

Query: 525 QGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS 571
           QGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS
Sbjct: 541 QGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS 587


>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
          Length = 796

 Score =  300 bits (767), Expect = 3e-81
 Identities = 159/264 (60%), Positives = 186/264 (70%), Gaps = 22/264 (8%)

Query: 329 PALTAVARTARKRKPSPEP-EGEVGPPKINGEAQ--PWLSTSTEGLKIPMTP-------- 377
           P+    A + RKRK SPEP +   G  K+  E Q   W++  +E LK+ M+         
Sbjct: 532 PSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGH 591

Query: 378 TSSFVSPPPPTASPHSNRTTPPEAA-QNGQSPMAALILVADNAGGSHASKDANQVHSTT- 435
            +    PPPP   PHSNRTTPPE+A QNG SPMAAL+ VAD  G +H+ KD + VHSTT 
Sbjct: 592 AAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTA 651

Query: 436 --RRNSNSPPSPSSM-NQRRLGPR------EVGGQGAGNTGGLEPVHPASLPDSSLATSA 486
             RRNS+SP SP+S+  QRRL  R      +V         G++ VHP ++PDS +A S 
Sbjct: 652 SARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSG 711

Query: 487 PLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNV 546
           PLCCT+CHERLEDTHFVQCPSVPSHKFCFPCSR+SIK QGA+GEVYCPSGEKCPLVGSNV
Sbjct: 712 PLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNV 771

Query: 547 PWAFMQGEIATILAGDVKVKKERD 570
           PWAFMQGEIATILAGDVKVKKERD
Sbjct: 772 PWAFMQGEIATILAGDVKVKKERD 795



 Score =  205 bits (522), Expect = 8e-53
 Identities = 167/425 (39%), Positives = 198/425 (46%), Gaps = 125/425 (29%)

Query: 4   AVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAH 63
           + A  ++SRRQSCYLCDLPRMPWAMIWDF+EPVCRGCVNYEGADR+EFVIETARQLKRAH
Sbjct: 2   SAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAH 61

Query: 64  GCFPEGRSP----------------PGAAASAAAKPPPLSA---------------KDIL 92
           GCF +GRSP                  AAA+AAA     +A               +   
Sbjct: 62  GCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQ 121

Query: 93  LQQQQQLGHGGPEAAP---RAPQALERYPL------AAAAERPPRLGSDFGSSRPAASLA 143
            QQQQQL H    + P    AP  LERY L      AAAA       S F    P  SL 
Sbjct: 122 QQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLG 181

Query: 144 QPPTPQPPPVNGILVPNGFSK---LEEPPELNRQSPN---------PRRGH--------- 182
                   P NG+  PNGF K    E PPELNRQSPN          RRG          
Sbjct: 182 SSSHTARLP-NGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLP 240

Query: 183 ----------AVPPTLVP--LMNGSAT------PLPTALG------------------LG 206
                      VPP L+P  L+NG A+      P P ALG                  LG
Sbjct: 241 NPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLG 300

Query: 207 GRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAH 266
           G    S  + S +++ S   A+       KRP SVSS+       +E   KEKQ      
Sbjct: 301 GTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSST------DQERELKEKQ------ 348

Query: 267 RGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFK 326
                    A   AELS     +S  +  ++W ++PK VRDTLL L       P+E +FK
Sbjct: 349 -------RNAEALAELS-----ESLRNRAEEWASKPKMVRDTLLTL---AGCTPYEVRFK 393

Query: 327 KEPAL 331
           K+ +L
Sbjct: 394 KDHSL 398



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 49/204 (24%), Positives = 66/204 (32%), Gaps = 36/204 (17%)

Query: 71  SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQAL------ERYPLAAAAE 124
           +PPG  A   A P    A   L +++       PE    A  AL      +R    A   
Sbjct: 520 APPGTGALPPAAPSGRGAAASLRKRK-----ASPEPPDSAEGALKLGEEQQRQQWMANQS 574

Query: 125 RPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAV 184
              +L    G        A  P P PPP+               P  NR +P        
Sbjct: 575 EALKLTMSAGGFAAPGHAAGGPPPPPPPLG--------------PHSNRTTPPESAPQNG 620

Query: 185 PPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSS 244
           P  +  LM+ + T     LG         +  S TA+A   S+ P        PASV   
Sbjct: 621 PSPMAALMSVADT-----LGTAHSPKDGSSVHSTTASARRNSSSPVS------PASVPGQ 669

Query: 245 AAVEHEQREAAAKEKQPPPPAHRG 268
             +     +   +   PPP AH G
Sbjct: 670 RRLASRNGDLNLQVAPPPPSAHPG 693


>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
           sapiens]
          Length = 584

 Score =  192 bits (489), Expect = 5e-49
 Identities = 118/240 (49%), Positives = 134/240 (55%), Gaps = 33/240 (13%)

Query: 334 VARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHS 393
           +A T R+RK SPEPEGE        E Q                   +V+P      P+S
Sbjct: 374 LAPTPRRRKASPEPEGEAAGKMTTEEQQQ----------------RHWVAP----GGPYS 413

Query: 394 NRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMN---Q 450
             T          SP+AAL  VA+  G  H+ KD        R    SP + S+     Q
Sbjct: 414 AETP------GVPSPIAALKNVAEALG--HSPKDPGGGGGPVRAGGASPAASSTAQPPTQ 465

Query: 451 RRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPS 510
            RL  R  G      T G E V       +     APLCCTLC ERLEDTHFVQCPSVP 
Sbjct: 466 HRLVARN-GEAEVSPTAGAEAVSGGG-SGTGATPGAPLCCTLCRERLEDTHFVQCPSVPG 523

Query: 511 HKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERD 570
           HKFCFPCSR+ IK QG +GEVYCPSG+KCPLVGS+VPWAFMQGEIATILAGD+KVKKERD
Sbjct: 524 HKFCFPCSREFIKAQGPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERD 583



 Score =  129 bits (323), Expect = 9e-30
 Identities = 120/355 (33%), Positives = 152/355 (42%), Gaps = 95/355 (26%)

Query: 5   VAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHG 64
           +A   ASRRQ CYLCDLP+MPWAM+WDF+E VCRGCVN+EGADR+E +I+ ARQLKR+H 
Sbjct: 1   MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSH- 59

Query: 65  CFPEGRSPPGAA---------ASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALE 115
             PEGRSP   A         A+AAA+ P L        Q Q  G GG           +
Sbjct: 60  VLPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQ---AQPQPSGTGG------GVSGQD 110

Query: 116 RYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQS 175
           RY  A ++ R P                  P+P      G  + NG  + E   E  R++
Sbjct: 111 RYDRATSSGRLPL-----------------PSPALEYTLGSRLANGLGREEAVAEGARRA 153

Query: 176 PNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAH 235
                       L+  M G   P     GL   A + L +   T A  L  A+P      
Sbjct: 154 ------------LLGSMPGLMPP-----GLLAAAVSGLGSRGLTLAPGLSPARPL----- 191

Query: 236 KRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGE 295
                  S    E +QR                 AD L      AEL+    G++     
Sbjct: 192 -----FGSDFEKEKQQRN----------------ADCL------AELNEAMRGRA----- 219

Query: 296 QDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALT--AVARTARKRKPSPEPE 348
           ++W  RPK VR+ LLAL       PF  +FKK+  L     A  A  R P  E E
Sbjct: 220 EEWHGRPKAVREQLLAL---SACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFE 271


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 80/392 (20%), Positives = 139/392 (35%), Gaps = 23/392 (5%)

Query: 69  GRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPR 128
           G + P       AKPPP          QQ    G  +  P+ P   +  P    + +PP 
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQP---GSTKPPPQQPGPAKPSPQQPGSTKPP- 530

Query: 129 LGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTL 188
                GS++P+A    P  P        +   G  K  +PP ++  +  P     +P T+
Sbjct: 531 -SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP-SQGLPKTI 588

Query: 189 VPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVE 248
            PL N +       L +  +A  +      T   SL    P       +     +     
Sbjct: 589 CPLCNTTEL----LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644

Query: 249 HEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDT 308
               + A     P P     P  + S  + ++    + + K   + +QD    P+  +  
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704

Query: 309 LLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTST 368
            L      H  P  +K K+ P   ++++ A  ++PS   E +  P   +   QP +   T
Sbjct: 705 PLVKQPTLHGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763

Query: 369 EGLKIPMTPTSSFVSPPPPTASPHSNRTTPP---EAAQNGQS--PMAALILVADNAGGSH 423
             L    + T+    P     S    +TTPP   ++A+  QS  P    +   D+     
Sbjct: 764 TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823

Query: 424 ASKDANQVHSTTRRNSNSPPSPSSMNQRRLGP 455
            + D+  +       S+  PS  S  Q+++ P
Sbjct: 824 PASDSKII-------SHPGPSSESKGQKQVDP 848



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 90/396 (22%), Positives = 132/396 (33%), Gaps = 52/396 (13%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHG----GPEAAPRAPQALERYPLAAA 122
           P+ + P          P  +S++     + Q  G G    GP   P+   A  + PL   
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRD 277

Query: 123 AERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGH 182
           A RP    +D    R  +     P+P  PP+     P       + P   +  P P +  
Sbjct: 278 ASRPQTKQADI--VRGESVKPSLPSPSKPPIQQ---PTPGKPPAQQPGHEKSQPGPAKPP 332

Query: 183 AVPPTLV-PLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASV 241
           A P  L  PL     T  P     G                +   AQP  LG  K PA  
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPG---------------TTKPPAQP--LGPAKPPAQQ 375

Query: 242 SSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNR 301
           + S     EQ     K    PP   + PA       G A+   +  G  +   +Q  +  
Sbjct: 376 TGSEKPSSEQ--PGPKALAQPPGVGKTPAQQ----PGPAKPPTQQVGTPKPLAQQPGLQS 429

Query: 302 P-KTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEA 360
           P K    T   + Q G  G   ++ +  P  T+  +T   + PS  P     PP+  G A
Sbjct: 430 PAKAPGPTKTPVQQPG-PGKIPAQ-QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487

Query: 361 QPWLSTSTEGLKIPMTPTSSFVSPP-----PPTASPHSNRTTPPEAAQNGQSPMAALILV 415
           +P       G   P +       PP     P   SP    +T P + Q G +  +A    
Sbjct: 488 KP--PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545

Query: 416 ADNAGGSHASKDANQVHS-------TTRRNSNSPPS 444
                   ++K  +Q  S       T   ++  PPS
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 76/374 (20%), Positives = 123/374 (32%), Gaps = 84/374 (22%)

Query: 67   PEGRSPPG--------AAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYP 118
            PE + PP          + SA AK PP         +   L    P   P  P   ++ P
Sbjct: 698  PEPKKPPPLVKQPTLHGSPSAKAKQPP---------EADSLSKPAPPKEPSVPSEQDKAP 748

Query: 119  LAAAAERPPRL---GSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEP--PELNR 173
            +A    + P++    +D  SS  A +    P+ +             S+ EE   P L  
Sbjct: 749  VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ-----------SQAEEKTTPPLKT 797

Query: 174  QSPNPRRGHAVPPT--LVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTD 231
             S  P +  + PPT   V   +  A P P +        + + +  G ++ S G  Q   
Sbjct: 798  DSAKPSQ--SFPPTGEKVSPFDSKAIPRPAS-------DSKIISHPGPSSESKGQKQVDP 848

Query: 232  LGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSR 291
            +   + P    +  + + + +        PP     GP  +        + S +   +SR
Sbjct: 849  VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP-----GPRPTAGQTVPTPQQSPKPQEQSR 903

Query: 292  ------GSGEQDWVNRPKTVRDTLLA----------------LHQHGHSGPFESKFKKEP 329
                  GS      ++P T ++T+                  +   G  GP        P
Sbjct: 904  RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963

Query: 330  ALTAVARTARKRKPSP-EPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSP---P 385
                      K+ P+P +P    GPPK  G+A P  + S    K    P +  + P    
Sbjct: 964  M---------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ 1014

Query: 386  PPTASPHSNRTTPP 399
             PT         PP
Sbjct: 1015 APTVKRTETEKKPP 1028



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 90/439 (20%), Positives = 138/439 (31%), Gaps = 47/439 (10%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALER--------YP 118
           PEG +   AA   A+     S   I    +  L     E   +    + R         P
Sbjct: 13  PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP 72

Query: 119 LAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNP 178
            AAA         +  SS P     +PP P  P         G SK         +   P
Sbjct: 73  PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP------AQPGLSKSRTTDTFRSEQKLP 126

Query: 179 RRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAAS--LGSAQPTDLGAHK 236
            R    P T+    + S T L             L+ V+  +A S  +    P DL +  
Sbjct: 127 GRS---PSTISLKESKSRTDLKEE-HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182

Query: 237 RPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAE--LSAEGAGKSRGSG 294
             +   ++   +  Q+E    E    PP  + P   +    G     L  +G  KS  S 
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ 242

Query: 295 EQDWVNR--PKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTAR-KRKPSPEPEGEV 351
           + + +    P T +            GP ++       L      +R + K +    GE 
Sbjct: 243 QPEKIKSQPPGTGKPI---------QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293

Query: 352 GPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNG--QSPM 409
             P +   ++P +   T G      P      P P       +  T P A Q G  + P+
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353

Query: 410 AALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGL 469
                    A     +K   Q  + + + S+  P P ++ Q           G G T   
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQ-QTGSEKPSSEQPGPKALAQ---------PPGVGKTPAQ 403

Query: 470 EPVHPASLPDSSLATSAPL 488
           +P  PA  P   + T  PL
Sbjct: 404 QP-GPAKPPTQQVGTPKPL 421


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 80/392 (20%), Positives = 139/392 (35%), Gaps = 23/392 (5%)

Query: 69  GRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPR 128
           G + P       AKPPP          QQ    G  +  P+ P   +  P    + +PP 
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQP---GSTKPPPQQPGPAKPSPQQPGSTKPP- 530

Query: 129 LGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTL 188
                GS++P+A    P  P        +   G  K  +PP ++  +  P     +P T+
Sbjct: 531 -SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP-SQGLPKTI 588

Query: 189 VPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVE 248
            PL N +       L +  +A  +      T   SL    P       +     +     
Sbjct: 589 CPLCNTTEL----LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644

Query: 249 HEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDT 308
               + A     P P     P  + S  + ++    + + K   + +QD    P+  +  
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704

Query: 309 LLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTST 368
            L      H  P  +K K+ P   ++++ A  ++PS   E +  P   +   QP +   T
Sbjct: 705 PLVKQPTLHGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763

Query: 369 EGLKIPMTPTSSFVSPPPPTASPHSNRTTPP---EAAQNGQS--PMAALILVADNAGGSH 423
             L    + T+    P     S    +TTPP   ++A+  QS  P    +   D+     
Sbjct: 764 TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823

Query: 424 ASKDANQVHSTTRRNSNSPPSPSSMNQRRLGP 455
            + D+  +       S+  PS  S  Q+++ P
Sbjct: 824 PASDSKII-------SHPGPSSESKGQKQVDP 848



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 90/396 (22%), Positives = 132/396 (33%), Gaps = 52/396 (13%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHG----GPEAAPRAPQALERYPLAAA 122
           P+ + P          P  +S++     + Q  G G    GP   P+   A  + PL   
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRD 277

Query: 123 AERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGH 182
           A RP    +D    R  +     P+P  PP+     P       + P   +  P P +  
Sbjct: 278 ASRPQTKQADI--VRGESVKPSLPSPSKPPIQQ---PTPGKPPAQQPGHEKSQPGPAKPP 332

Query: 183 AVPPTLV-PLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASV 241
           A P  L  PL     T  P     G                +   AQP  LG  K PA  
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPG---------------TTKPPAQP--LGPAKPPAQQ 375

Query: 242 SSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNR 301
           + S     EQ     K    PP   + PA       G A+   +  G  +   +Q  +  
Sbjct: 376 TGSEKPSSEQ--PGPKALAQPPGVGKTPAQQ----PGPAKPPTQQVGTPKPLAQQPGLQS 429

Query: 302 P-KTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEA 360
           P K    T   + Q G  G   ++ +  P  T+  +T   + PS  P     PP+  G A
Sbjct: 430 PAKAPGPTKTPVQQPG-PGKIPAQ-QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487

Query: 361 QPWLSTSTEGLKIPMTPTSSFVSPP-----PPTASPHSNRTTPPEAAQNGQSPMAALILV 415
           +P       G   P +       PP     P   SP    +T P + Q G +  +A    
Sbjct: 488 KP--PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545

Query: 416 ADNAGGSHASKDANQVHS-------TTRRNSNSPPS 444
                   ++K  +Q  S       T   ++  PPS
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 76/374 (20%), Positives = 123/374 (32%), Gaps = 84/374 (22%)

Query: 67   PEGRSPPG--------AAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYP 118
            PE + PP          + SA AK PP         +   L    P   P  P   ++ P
Sbjct: 698  PEPKKPPPLVKQPTLHGSPSAKAKQPP---------EADSLSKPAPPKEPSVPSEQDKAP 748

Query: 119  LAAAAERPPRL---GSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEP--PELNR 173
            +A    + P++    +D  SS  A +    P+ +             S+ EE   P L  
Sbjct: 749  VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ-----------SQAEEKTTPPLKT 797

Query: 174  QSPNPRRGHAVPPT--LVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTD 231
             S  P +  + PPT   V   +  A P P +        + + +  G ++ S G  Q   
Sbjct: 798  DSAKPSQ--SFPPTGEKVSPFDSKAIPRPAS-------DSKIISHPGPSSESKGQKQVDP 848

Query: 232  LGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSR 291
            +   + P    +  + + + +        PP     GP  +        + S +   +SR
Sbjct: 849  VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP-----GPRPTAGQTVPTPQQSPKPQEQSR 903

Query: 292  ------GSGEQDWVNRPKTVRDTLLA----------------LHQHGHSGPFESKFKKEP 329
                  GS      ++P T ++T+                  +   G  GP        P
Sbjct: 904  RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963

Query: 330  ALTAVARTARKRKPSP-EPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSP---P 385
                      K+ P+P +P    GPPK  G+A P  + S    K    P +  + P    
Sbjct: 964  M---------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ 1014

Query: 386  PPTASPHSNRTTPP 399
             PT         PP
Sbjct: 1015 APTVKRTETEKKPP 1028



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 90/439 (20%), Positives = 138/439 (31%), Gaps = 47/439 (10%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALER--------YP 118
           PEG +   AA   A+     S   I    +  L     E   +    + R         P
Sbjct: 13  PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP 72

Query: 119 LAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNP 178
            AAA         +  SS P     +PP P  P         G SK         +   P
Sbjct: 73  PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP------AQPGLSKSRTTDTFRSEQKLP 126

Query: 179 RRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAAS--LGSAQPTDLGAHK 236
            R    P T+    + S T L             L+ V+  +A S  +    P DL +  
Sbjct: 127 GRS---PSTISLKESKSRTDLKEE-HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182

Query: 237 RPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAE--LSAEGAGKSRGSG 294
             +   ++   +  Q+E    E    PP  + P   +    G     L  +G  KS  S 
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ 242

Query: 295 EQDWVNR--PKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTAR-KRKPSPEPEGEV 351
           + + +    P T +            GP ++       L      +R + K +    GE 
Sbjct: 243 QPEKIKSQPPGTGKPI---------QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293

Query: 352 GPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNG--QSPM 409
             P +   ++P +   T G      P      P P       +  T P A Q G  + P+
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353

Query: 410 AALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGL 469
                    A     +K   Q  + + + S+  P P ++ Q           G G T   
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQ-QTGSEKPSSEQPGPKALAQ---------PPGVGKTPAQ 403

Query: 470 EPVHPASLPDSSLATSAPL 488
           +P  PA  P   + T  PL
Sbjct: 404 QP-GPAKPPTQQVGTPKPL 421


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 110/463 (23%), Positives = 148/463 (31%), Gaps = 65/463 (14%)

Query: 71   SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLG 130
            SP GA  + AA PP           +  L    P+ AP  P A    P    A   P+  
Sbjct: 1190 SPKGAPTTPAATPP---------SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240

Query: 131  SDFGSSRPAASLAQPPTPQP---PPVNGILVPNGFSKLEEPPELNRQSP----------- 176
                ++ P +    P TP P   P       P+    L  PP     +P           
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 177  ---NPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLG 233
               +P +G   PP   P     +   P   G     A +  +  GT   +L +  P+  G
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT--PTLPATTPSSKG 1358

Query: 234  AHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPA------DSLSTA--------AGA 279
                P+S                    PP P  RGPA      D  S A        A A
Sbjct: 1359 GPTTPSSKEGPTPPAATPSHKGGPAMTPPSP-KRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417

Query: 280  AELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTAR 339
              ++ EGA              P +++         G  GP     K +P L AV   + 
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG--GPATPSSKGDPTLPAVTPPSP 1475

Query: 340  KRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTP------TSSFVSPPPPTASPHS 393
            K  P+P+       PK        +   T    IP +P       SS   P  PTA+  S
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535

Query: 394  NRT----TPPEA----AQNGQSP-MAALILVADNAGGSHASKDANQVHSTTRRNSNSPPS 444
             +T     P EA    A    SP     I     A  + +SK+A+   + T       PS
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS 1595

Query: 445  PSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAP 487
            P  +    L P  V             V P S P+   AT AP
Sbjct: 1596 PKEL----LIPPAVTSPSPKEAPTPPAVTPPS-PEKGPATPAP 1633



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 102/445 (22%), Positives = 158/445 (35%), Gaps = 66/445 (14%)

Query: 67   PEGRSPP---GAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAA 123
            P G +P    G +       P L     L  +   +  G     P  P A E  P+A + 
Sbjct: 655  PAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP 714

Query: 124  ERPPR------LGSDFGSSRPAASLAQPPTPQPP---PVNGILVPNGFSKLEEPPELNRQ 174
            +          L  +   S P+ SL  PP   PP    V+GI   +  + +   P   ++
Sbjct: 715  QNTCAPLATLVLAPEIPKSVPSPSL--PPAGTPPGTKKVDGISHTSALAPVASSP---KE 769

Query: 175  SPNPRRGHAVPPTLVPLMNGSATPL---PTALGLGGRAAASLAAVSGTAAASLGSAQP-T 230
             P    G +   +      G+ T L   P+ LG+      S++  +       GSA P T
Sbjct: 770  CPTEDSGASATAS----SKGTLTYLADSPSPLGV------SVSPQTKRPPTKKGSAGPDT 819

Query: 231  DLGAHKRPAS-VSSSAAVEHE-----QREAAAKEKQPPPPAHRGPADSLSTAAGAAELSA 284
             +G    P S V +S   E+       +++ A    P PP+ +G      T +    LS 
Sbjct: 820  PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP----TPSAVTPLSP 875

Query: 285  EGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPS 344
            +G               PK      +        GP     K+ PAL+  + + +K + +
Sbjct: 876  KGVTLP-----------PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924

Query: 345  PEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQN 404
            P P+G    P   G   P  +T       P TP+  + +P PP A+P S +  P   +  
Sbjct: 925  PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW-APTPPAATPPSPKGGPATPSPK 983

Query: 405  G-QSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGA 463
            G  +P AA          + + K A    + T      PPSP         P+     GA
Sbjct: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVT------PPSPKGSPAATPFPK-----GA 1032

Query: 464  GNTGGLEPVHPASLPDSS-LATSAP 487
                   P  P   P ++ L   AP
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAP 1057



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 103/446 (23%), Positives = 146/446 (32%), Gaps = 55/446 (12%)

Query: 71   SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLG 130
            SP G + S   K PP              G  GP+  P    +    P+ A+      L 
Sbjct: 795  SPLGVSVSPQTKRPPTKK-----------GSAGPDT-PIGNLSSPVSPVEASFLPENSLS 842

Query: 131  SDFGSSRPAASLAQ-PPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLV 189
                   PA + +  PP+P+  P    + P     +  PP   +++P P   +   P   
Sbjct: 843  FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP---KETPTPSVVNLPFPK-- 897

Query: 190  PLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSS---AA 246
                G ATP P         ++S      T A     A P+  GA   PA+   S     
Sbjct: 898  ---EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954

Query: 247  VEHEQREAAAKEKQPPPPAHRGPAD----SLSTAAGAAELSAEGAGKS---RGSGEQDWV 299
                 + A       PP    GPA        T   A   S +G   +   +G+     V
Sbjct: 955  ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014

Query: 300  NRPKTVRDTLLALHQHGHSGPFES---KFKKEPALTAVARTARKRKPS--PEPEGEVGPP 354
              P             G S P  +     K  PA T + + A     +  P P+G    P
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 355  KINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNR---TTPPEAAQNGQSPMAA 411
             + G   P  +T       P TP S   +P PP A+P S +    TPP       +P   
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATP-SPKGAPMPPAATPPSPKGGLATPPHKG----APTTP 1129

Query: 412  LILVADNAGG--SHASKDANQVHSTTRRN-----SNSPPSPSSMNQRRLGPREVGGQGAG 464
                    GG  +   K A    + T  +     +  PP  +        P   GG    
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189

Query: 465  NTGGLEPVHPASLPDS---SLATSAP 487
            +  G  P  PA+ P S    LAT +P
Sbjct: 1190 SPKG-APTTPAATPPSPKGGLATPSP 1214



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 78/349 (22%), Positives = 120/349 (34%), Gaps = 50/349 (14%)

Query: 71   SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLG 130
            SP    A+ +++  P++    LL ++       P+ A   P      P    A   P+  
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLA-PKEALIPPAMTVPSPKKTPAIPTPKEA 1570

Query: 131  SDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVP 190
                SS+ A+S   PP   P    G   P    +L  PP +   SP+P+     PP + P
Sbjct: 1571 PATPSSKEASS---PPAVTPSTYKGAPSPK---ELLIPPAVT--SPSPKEA-PTPPAVTP 1621

Query: 191  LM--NGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVE 248
                 G ATP P           S    S T+ AS+       +    +           
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681

Query: 249  HEQREAAAKEKQP--PPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVR 306
             E   A A E  P    P  +GP    S+A          A                   
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA------------------- 1722

Query: 307  DTLLALHQHGHSGPFESKFKKE--PALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWL 364
                   ++G  GP  +       P     ++TA+ +  S  P+G + PP+ +  + P  
Sbjct: 1723 -------KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE-SKASTPLT 1774

Query: 365  STSTEGLKIPMTPTSSFVS--PPPPTA---SPHSNRTTPPEAAQNGQSP 408
            + + E  K+   P S+ VS  P PP +   +P    T PP+      SP
Sbjct: 1775 AAAFE--KVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 39/151 (25%), Positives = 56/151 (37%), Gaps = 18/151 (11%)

Query: 99  LGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILV 158
           LG  GP   P    A ++ PL+AA +  P     F S    AS      P P   +G  +
Sbjct: 38  LGQPGPTLPPPCSPAPQQCPLSAANQASP-----FPSPSTIAS-TPLEVPFPQSSSGTAL 91

Query: 159 PNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPL--PTALGLGGRAAASLAAV 216
           P G +     PE     PN      + P + P     A+P+  PT  G    +A      
Sbjct: 92  PLGTA-----PEAPTFLPN-----LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVA 141

Query: 217 SGTAAASLGSAQPTDLGAHKRPASVSSSAAV 247
               +    SA P +L       +V+ S +V
Sbjct: 142 LAPHSVQKSSAFPPNLLTSPPSVAVAESGSV 172


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 78/260 (30%), Positives = 100/260 (38%), Gaps = 40/260 (15%)

Query: 54  ETARQLKRAHGCFPEGRS---PPGAAASAA-AKPPP--------------LSAKDILLQQ 95
           E +R  + A G   +G     PP A AS A A PPP              +SA D   + 
Sbjct: 304 EVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERH 363

Query: 96  QQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPT-PQPPPVN 154
            +  G GG   APR   A    P  +    P ++ S  G  RPA +L  PPT   P P N
Sbjct: 364 FRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTN 423

Query: 155 GILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLA 214
           G  +  G   L+E P L   +P P      PP L P      TPLP A  L        +
Sbjct: 424 GEPMRPGPPGLQELPPLPPPTPPPT---LQPPALQP------TPLPVAPPLTPGLGHKES 474

Query: 215 AVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLS 274
           A++ TAA +L    P  L A + PA   + A            E  PP  A    A  + 
Sbjct: 475 ALAPTAAPAL----PPALAADQAPAPSPAPA--------PTVAEPSPPVSAPAPAAAPIK 522

Query: 275 TAAGAAELSAEGAGKSRGSG 294
           T     + S    G +R  G
Sbjct: 523 TRTRRNKGSRAARGATRKDG 542



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 125/545 (22%), Positives = 173/545 (31%), Gaps = 138/545 (25%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDIL-------------------LQQQQQLGHGGP--- 104
           P    PP   A+A + PPP  A  +L                   L +    G G P   
Sbjct: 80  PSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSL 139

Query: 105 ---------------EAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQP--PT 147
                          +  PRAP      P     + PP L S+    +PA     P   T
Sbjct: 140 RPLKPPPPPRQLSVKDTVPRAPSQFP--PPLETWKPPPPLPSE---RQPADRRITPALAT 194

Query: 148 PQPPPVNGILVPN------GFSKLEEPPELNR----QSPNPRRGHAV--------PPTLV 189
           P  PP      P       G ++   PP        Q  +   G ++         P+L 
Sbjct: 195 PASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLA 254

Query: 190 PLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEH 249
           P    S+     +LG GG      AA    + A +    P   GA  RP    S  A E 
Sbjct: 255 PPAASSSLAAKASLG-GGGGGGLFAASGAISYAEVLKQGPLPPGA-ARPLGEVSRGAQEA 312

Query: 250 EQREAAAKEKQPPPPAHRGPADSL-----STAAGAAE----LSAEGAGKS--RGSGEQDW 298
           E  +   +    PP A    A +L     +T  G+      +SA    +   R +G    
Sbjct: 313 EGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGG 372

Query: 299 VNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSP---EPEGEVGPPK 355
           +  P+     L        SGP+ S     P    +      R+P+P    P   + P  
Sbjct: 373 IGAPRRRAAAL--------SGPWGS---PPPPPEQIHSAPGPRRPAPALLAPPTFIFPAP 421

Query: 356 INGE----AQPWLS--------TSTEGLKIP-MTPTSSFVSPP------------PPTAS 390
            NGE      P L         T    L+ P + PT   V+PP             PTA+
Sbjct: 422 TNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAA 481

Query: 391 PHSNRTTPPEAAQN---GQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSS 447
           P      PP  A +     SP  A  +   +   S  +  A  + + TRRN  S  +  +
Sbjct: 482 P----ALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGA 537

Query: 448 MNQRRL---GPRE-------------VGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCT 491
             +  L   GPRE              GG GA  TG              +  S P C  
Sbjct: 538 TRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCP-CKC 596

Query: 492 LCHER 496
            CH +
Sbjct: 597 YCHHQ 601


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 92/342 (26%), Positives = 122/342 (35%), Gaps = 60/342 (17%)

Query: 71  SPPGAAASAAAKPPPLSAKDILLQQQQQLG-------HGGPEAAPRA----PQALERYPL 119
           SP   AA A   P PL         Q+ +G       H   + AP+     P   +   L
Sbjct: 591 SPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNL 650

Query: 120 AAAAERPPRLGSDFGSSRPAASL-----AQPPTPQPPPVNGILVPNGFSKLEEPPELNRQ 174
               ERPP+L S      P   +       P +P P P  G   P  FS L  PP     
Sbjct: 651 PEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPG--APWAFSYLAGPPATPPD 708

Query: 175 SPNP-RRGHAVP---PTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPT 230
            P P RR H++    PT       +  P+ + LG    + A+L    G +A    S   T
Sbjct: 709 PPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLG----SYATLTRRPGRSALVRTSPSVT 764

Query: 231 DLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKS 290
              A   P S S +           A+ K PPPP    P   LS+ +G    S E     
Sbjct: 765 PTPARGTPRSQSFA---------LRARRKGPPPP----PPKRLSSVSGP---SPEPPPLD 808

Query: 291 RGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGE 350
              G ++    P+  R TL        +GP E      PA    A    + +P PE    
Sbjct: 809 ESPGPKEGATGPR--RRTL-----SEPAGPSEP--PGPPAPAGPASDTEEEEPGPE---- 855

Query: 351 VGPPKINGEAQPWLSTSTEG-LKIPMTPTSSFVSPPPPTASP 391
            G P   G +   L  + EG L I   P     + PPP  +P
Sbjct: 856 -GTPPSRGSSGEGLPFAEEGNLTIKQRPKP---AGPPPRETP 893



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 80/305 (26%), Positives = 105/305 (34%), Gaps = 56/305 (18%)

Query: 102  GGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAA-----SLAQPPTPQPPPVNGI 156
            G P  A  A    E  P       PP  GS  G   P A     ++ Q P P  PP    
Sbjct: 836  GPPAPAGPASDTEEEEP--GPEGTPPSRGSS-GEGLPFAEEGNLTIKQRPKPAGPPPRET 892

Query: 157  LVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAV 216
             VP G        +  ++ P  R    +   L+     SATP P A         S    
Sbjct: 893  PVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA------PLPSPTPG 946

Query: 217  SGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTA 276
                A+SL   +P+ L A   P  ++ S A+            QPP P   GP    S A
Sbjct: 947  ESPPASSLPQPEPSSLPAQGVPTPLAPSPAM------------QPPVPPCPGPGLESSAA 994

Query: 277  A---GAAELSAEGAG--KSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPAL 331
            +   G  E  A  A   K  G+G       PK V    +A  Q   SGP     K  P  
Sbjct: 995  SRWNGETEPPAAPAALLKVPGAG-----TAPKPVS---VACTQLAFSGP-----KLAP-- 1039

Query: 332  TAVARTARKRKPSPEPE--GEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTA 389
                R   +  P P PE  G VGP    G+AQ  L  ++  L   +      +       
Sbjct: 1040 ----RLGPRPVPPPRPESTGTVGP----GQAQQRLEQTSSSLAAALRAAEKSIGTKEQEG 1091

Query: 390  SPHSN 394
            +P ++
Sbjct: 1092 TPSAS 1096


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 92/342 (26%), Positives = 122/342 (35%), Gaps = 60/342 (17%)

Query: 71  SPPGAAASAAAKPPPLSAKDILLQQQQQLG-------HGGPEAAPRA----PQALERYPL 119
           SP   AA A   P PL         Q+ +G       H   + AP+     P   +   L
Sbjct: 673 SPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNL 732

Query: 120 AAAAERPPRLGSDFGSSRPAASL-----AQPPTPQPPPVNGILVPNGFSKLEEPPELNRQ 174
               ERPP+L S      P   +       P +P P P  G   P  FS L  PP     
Sbjct: 733 PEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPG--APWAFSYLAGPPATPPD 790

Query: 175 SPNP-RRGHAVP---PTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPT 230
            P P RR H++    PT       +  P+ + LG    + A+L    G +A    S   T
Sbjct: 791 PPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLG----SYATLTRRPGRSALVRTSPSVT 846

Query: 231 DLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKS 290
              A   P S S +           A+ K PPPP    P   LS+ +G    S E     
Sbjct: 847 PTPARGTPRSQSFA---------LRARRKGPPPP----PPKRLSSVSGP---SPEPPPLD 890

Query: 291 RGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGE 350
              G ++    P+  R TL        +GP E      PA    A    + +P PE    
Sbjct: 891 ESPGPKEGATGPR--RRTL-----SEPAGPSEP--PGPPAPAGPASDTEEEEPGPE---- 937

Query: 351 VGPPKINGEAQPWLSTSTEG-LKIPMTPTSSFVSPPPPTASP 391
            G P   G +   L  + EG L I   P     + PPP  +P
Sbjct: 938 -GTPPSRGSSGEGLPFAEEGNLTIKQRPKP---AGPPPRETP 975



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 80/305 (26%), Positives = 105/305 (34%), Gaps = 56/305 (18%)

Query: 102  GGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAA-----SLAQPPTPQPPPVNGI 156
            G P  A  A    E  P       PP  GS  G   P A     ++ Q P P  PP    
Sbjct: 918  GPPAPAGPASDTEEEEP--GPEGTPPSRGSS-GEGLPFAEEGNLTIKQRPKPAGPPPRET 974

Query: 157  LVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAV 216
             VP G        +  ++ P  R    +   L+     SATP P A         S    
Sbjct: 975  PVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA------PLPSPTPG 1028

Query: 217  SGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTA 276
                A+SL   +P+ L A   P  ++ S A+            QPP P   GP    S A
Sbjct: 1029 ESPPASSLPQPEPSSLPAQGVPTPLAPSPAM------------QPPVPPCPGPGLESSAA 1076

Query: 277  A---GAAELSAEGAG--KSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPAL 331
            +   G  E  A  A   K  G+G       PK V    +A  Q   SGP     K  P  
Sbjct: 1077 SRWNGETEPPAAPAALLKVPGAG-----TAPKPVS---VACTQLAFSGP-----KLAP-- 1121

Query: 332  TAVARTARKRKPSPEPE--GEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTA 389
                R   +  P P PE  G VGP    G+AQ  L  ++  L   +      +       
Sbjct: 1122 ----RLGPRPVPPPRPESTGTVGP----GQAQQRLEQTSSSLAAALRAAEKSIGTKEQEG 1173

Query: 390  SPHSN 394
            +P ++
Sbjct: 1174 TPSAS 1178


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 110/471 (23%), Positives = 161/471 (34%), Gaps = 67/471 (14%)

Query: 75  AAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRA-PQALERYPLAAAAERPP---RLG 130
           A A AAA+ P   A  +L  +      G P   P   P AL     A A  R P   R G
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPP----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 131 SDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVP 190
              G++ P ++    P   P    G    N  S+   PP   R    P   +  P  +  
Sbjct: 64  GIGGATIPESA----PRAGPTRSAGTSSRNPASR---PPASGRGERAPPAKNTSPGPVSS 116

Query: 191 LMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKR---PASVSSSAAV 247
               S T  P  LG  G   ++   V+   A           GA +    P   + S A+
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 248 EHEQREAAAKEKQPPP-------PAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN 300
               R A  +   P P       P   GP  S+S+A+  +      A + R S     + 
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-LQ 235

Query: 301 RP--KTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKING 358
           RP  +++  +   L     SGP      + PA           +P P+    + PP++  
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPA--------HPSQPKPKGLQALRPPQVTP 287

Query: 359 ---EAQPWLSTSTEGLKIPMTPTSSFVSPPPPT--ASPHSNRTT---------------P 398
              +A P L   +       +P+++  S  PPT  A+PHS+  T                
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347

Query: 399 PEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREV 458
           P + Q   SP A     A  + GS   +  +    +   +  + P P +     L P + 
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407

Query: 459 GGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVP 509
                       P  PAS P S LAT +P         L    F   PS P
Sbjct: 408 -----------PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 95/366 (25%), Positives = 127/366 (34%), Gaps = 44/366 (12%)

Query: 71  SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPR--APQALER---------YPL 119
           S PG A S   +P PL  K + +  ++ +  G    AP+  A  A  R          P 
Sbjct: 115 SSPGRA-SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173

Query: 120 AAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPR 179
            A A R    G++ G  RPA S A+P  P   P   +   +  S  E  P   R+   P 
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---PS 229

Query: 180 RGHAVPPTLVPLMNGSATPL-------PTALGLGGRAAASLAAVSGTAAASLGSAQPTDL 232
            G  +       ++ SATPL       P+A G   RA A  +        +L   Q T  
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPP 288

Query: 233 GAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRG 292
                PA    S++       +AA + Q PP     P  S  T   A  L       S  
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348

Query: 293 SGEQDWVNRPKTV---------RDTLLALHQHGHSGPFESKFKKEP-ALTAVARTARKRK 342
              Q   + P T            TL A H    S P        P A  A+A    +  
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 408

Query: 343 PSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPP------PPTASPHSNRT 396
           PSP     + P        P  + +   L+ P +P     SPP      PP + P S   
Sbjct: 409 PSPPASPPLSPLATPSPQAP-NALAVHLLQAPFSPPP---SPPVQAPFSPPASPPVSPSA 464

Query: 397 TPPEAA 402
           TPP  A
Sbjct: 465 TPPSQA 470



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 70/242 (28%), Positives = 82/242 (33%), Gaps = 40/242 (16%)

Query: 66  FPEGRSPPGAAASAAAKP---PPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAA 122
           FP G++P   +AS    P   PP  A  +L     Q+        P +P A    P   A
Sbjct: 538 FP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV--------PPSPPAS---PTLQA 585

Query: 123 AERPPRLGSDFGSSRPAASLAQPPTPQPPPVNG--------ILVPNGFSKLEEPPELNRQ 174
             RPP  G D   S P  +LA  P P PPP            L  +  S    P EL   
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645

Query: 175 SPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGA 234
              P  G A            A+P P A      AA   AA S   A  L          
Sbjct: 646 DSGPEGGAA------------ASPPPDA----ELAACHPAAWSRGPAPPLAFRGAPGAPL 689

Query: 235 HKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSG 294
              PA+   SA       E    E   P P    P  S  T+ G A   A GAG S  S 
Sbjct: 690 PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA-GAGASSRSP 748

Query: 295 EQ 296
           +Q
Sbjct: 749 KQ 750



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 124/508 (24%), Positives = 166/508 (32%), Gaps = 118/508 (23%)

Query: 59  LKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAP---------- 108
           L+  H   P   SPP    S  A PPP +   + L   Q      P A+P          
Sbjct: 374 LQATHSFLP---SPP---LSPLATPPPQAPPALALPPLQ--APPSPPASPPLSPLATPSP 425

Query: 109 RAPQALERYPLAAAAERPPRLGSDFGSSRPAA---------------SLAQPP--TPQPP 151
           +AP AL  + L A    PP        S PA+               SLA PP   P  P
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485

Query: 152 PVNGILVPNGFSKLEEP-----PELNRQSPNPRRGHAV----------PPTLVP------ 190
           P +  + P+     + P     P L    P P+   A+          PP   P      
Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 545

Query: 191 -----LMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSA 245
                 M+  ATP P A  +    AA L  V  +  AS     PT L A +RP +     
Sbjct: 546 PSASLPMSPLATPPPQAPPV---LAAPLLQVPPSPPAS-----PT-LQAPRRPPTPGPDT 596

Query: 246 AVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTV 305
           +V    R   A    PPPP  R P+ +LS          + AG S  +      + P+ +
Sbjct: 597 SVS-GPRLTLALAPGPPPPPSRSPSSTLS--------GPDLAGHSSSA-----TSTPEEL 642

Query: 306 RDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLS 365
           R      +  G  G   +    +  L A    A  R P+P P    G P   G   PW  
Sbjct: 643 RG-----YDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAP---GAPLPWPP 693

Query: 366 TSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHAS 425
            +  G    +        P   T +P +    P      G++   A       AG S  S
Sbjct: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA------GAGASSRS 747

Query: 426 K-------------DANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPV 472
                          A+ V     R      +  +      GP   G +G G TGG    
Sbjct: 748 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG--GAEGGGVTGGAR-- 803

Query: 473 HPASLPDSSLATSAPLCCTLCHERLEDT 500
             A+L D+ L   A L   L   R   T
Sbjct: 804 --AALSDAELGRWAELLSPLDESRASIT 829


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 92/356 (25%), Positives = 124/356 (34%), Gaps = 54/356 (15%)

Query: 71  SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPR--APQALER---------YPL 119
           S PG A S   +P PL  K + +  ++ +  G    AP+  A  A  R          P 
Sbjct: 106 SSPGRA-SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 164

Query: 120 AAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPR 179
            A A R    G++ G  RPA S A+P  P   P   +   +  S  E  P   R+   P 
Sbjct: 165 PAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---PS 220

Query: 180 RGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHK-RP 238
            G  +       ++ SATPL +        A S  +  GT  A    +QP   G    RP
Sbjct: 221 AGGGLQRPASRSLSSSATPLSS-------PARSGPSARGTPRAPAHPSQPKPKGLQALRP 273

Query: 239 ASVS-----SSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGS 293
             V+     ++ A+        A      PP+   P  SL T           A  S GS
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP-PSLQTLPSPPATPPSQATTSLGS 332

Query: 294 GEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEP-ALTAVARTARKRKPSPEPEGEVG 352
                         TL A H    S P        P A  A+A    +  PSP     + 
Sbjct: 333 -------------PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379

Query: 353 PPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPP------PPTASPHSNRTTPPEAA 402
           P        P  + +   L+ P +P     SPP      PP + P S   TPP  A
Sbjct: 380 PLATPSPQAP-NALAVHLLQAPFSPPP---SPPVQAPFSPPASPPVSPSATPPSQA 431



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 112/459 (24%), Positives = 152/459 (33%), Gaps = 82/459 (17%)

Query: 75  AAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRA-PQALERYPLAAAAERPP---RLG 130
           A A AAA+ P   A  +L  +      G P   P   P AL     A A  R P   R G
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPP----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 131 SDFGSSRP-AASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLV 189
              G++ P +A  A P     PP +G        + E  P     SP P           
Sbjct: 64  GIGGATIPESAPRAGPTRTSRPPASG--------RGERAPPAKNTSPGPVSSPG------ 109

Query: 190 PLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKR---PASVSSSAA 246
                S T  P  LG  G   ++   V+   A           GA +    P   + S A
Sbjct: 110 ---RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 166

Query: 247 VEHEQREAAAKEKQPPP-------PAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWV 299
           +    R A  +   P P       P   GP  S+S+A+  +      A + R S     +
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-L 225

Query: 300 NRP--KTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKIN 357
            RP  +++  +   L     SGP      + PA           +P P+    + PP++ 
Sbjct: 226 QRPASRSLSSSATPLSSPARSGPSARGTPRAPA--------HPSQPKPKGLQALRPPQVT 277

Query: 358 G---EAQPWLSTSTEGLKIPM-TPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALI 413
               +A P L   +     P+ TP+ S  +PP P+A P       P A    Q       
Sbjct: 278 PPRKDAAPALGPLSSS---PLATPSPS--APPSPSAPPSLQTLPSPPATPPSQ------- 325

Query: 414 LVADNAGGSHASKDANQVHSTTRRNSNSP---PSPSSMNQRRLGPREVGGQGAGNTGGLE 470
                A  S  S      HS       SP   P P +     L P +             
Sbjct: 326 -----ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA-----------P 369

Query: 471 PVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVP 509
           P  PAS P S LAT +P         L    F   PS P
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 70/242 (28%), Positives = 82/242 (33%), Gaps = 40/242 (16%)

Query: 66  FPEGRSPPGAAASAAAKP---PPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAA 122
           FP G++P   +AS    P   PP  A  +L     Q+        P +P A    P   A
Sbjct: 499 FP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV--------PPSPPAS---PTLQA 546

Query: 123 AERPPRLGSDFGSSRPAASLAQPPTPQPPPVNG--------ILVPNGFSKLEEPPELNRQ 174
             RPP  G D   S P  +LA  P P PPP            L  +  S    P EL   
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606

Query: 175 SPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGA 234
              P  G A            A+P P A      AA   AA S   A  L          
Sbjct: 607 DSGPEGGAA------------ASPPPDA----ELAACHPAAWSRGPAPPLAFRGAPGAPL 650

Query: 235 HKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSG 294
              PA+   SA       E    E   P P    P  S  T+ G A   A GAG S  S 
Sbjct: 651 PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA-GAGASSRSP 709

Query: 295 EQ 296
           +Q
Sbjct: 710 KQ 711



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 124/508 (24%), Positives = 166/508 (32%), Gaps = 118/508 (23%)

Query: 59  LKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAP---------- 108
           L+  H   P   SPP    S  A PPP +   + L   Q      P A+P          
Sbjct: 335 LQATHSFLP---SPP---LSPLATPPPQAPPALALPPLQ--APPSPPASPPLSPLATPSP 386

Query: 109 RAPQALERYPLAAAAERPPRLGSDFGSSRPAA---------------SLAQPP--TPQPP 151
           +AP AL  + L A    PP        S PA+               SLA PP   P  P
Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446

Query: 152 PVNGILVPNGFSKLEEP-----PELNRQSPNPRRGHAV----------PPTLVP------ 190
           P +  + P+     + P     P L    P P+   A+          PP   P      
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506

Query: 191 -----LMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSA 245
                 M+  ATP P A  +    AA L  V  +  AS     PT L A +RP +     
Sbjct: 507 PSASLPMSPLATPPPQAPPV---LAAPLLQVPPSPPAS-----PT-LQAPRRPPTPGPDT 557

Query: 246 AVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTV 305
           +V    R   A    PPPP  R P+ +LS          + AG S  +      + P+ +
Sbjct: 558 SVS-GPRLTLALAPGPPPPPSRSPSSTLS--------GPDLAGHSSSA-----TSTPEEL 603

Query: 306 RDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLS 365
           R      +  G  G   +    +  L A    A  R P+P P    G P   G   PW  
Sbjct: 604 RG-----YDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAP---GAPLPWPP 654

Query: 366 TSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHAS 425
            +  G    +        P   T +P +    P      G++   A       AG S  S
Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA------GAGASSRS 708

Query: 426 K-------------DANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPV 472
                          A+ V     R      +  +      GP   G +G G TGG    
Sbjct: 709 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG--GAEGGGVTGGAR-- 764

Query: 473 HPASLPDSSLATSAPLCCTLCHERLEDT 500
             A+L D+ L   A L   L   R   T
Sbjct: 765 --AALSDAELGRWAELLSPLDESRASIT 790


>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 100/404 (24%), Positives = 149/404 (36%), Gaps = 51/404 (12%)

Query: 68  EGRSPPGAAASAAA-KPPPLS-AKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAER 125
           E  S P    SA+A +PP LS  KD+    + + G G P  +P   +  E +    +A+R
Sbjct: 28  EALSQPTLRHSASALRPPRLSRGKDL----KPRCGRG-PAHSPDPGEGCEAWR-RLSADR 81

Query: 126 PPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELN---RQSPNPRRGH 182
            PR  S      P A+LA  P  +P P     +P   S +  PP       Q+P    G 
Sbjct: 82  WPRPAS----LSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137

Query: 183 AVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSG-TAAASLGSAQPTDLGAHKRPASV 241
                 + L+N S    P  +       AS A  SG TA     SA P   G  K   S 
Sbjct: 138 CARAKGIRLVNPSPPRPPEPI------PASAAVTSGLTARGPNTSATP---GPQKGRGSA 188

Query: 242 SSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNR 301
             +  +  +++  AA    PPPP        +    G++ LS     +  G G +    R
Sbjct: 189 ERTNHIPKDKQRVAA----PPPPER----PRVPFCRGSSGLSVPTPPEHAG-GRRKKFTR 239

Query: 302 PKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQ 361
            + +  T   L +   + P  +      A       +  R PSP P    G  ++   + 
Sbjct: 240 TRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF-WSPLRNPSPRPAPACGELRLGRLSP 298

Query: 362 PWLST---STEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADN 418
           P   T   S+ G   P +   +  +PP PTA P +     P  A++ + P          
Sbjct: 299 PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGP--------GP 350

Query: 419 AGGSHASKDANQ-----VHSTTRRNSNSPPSPSSMNQRRLGPRE 457
           A G  + +D  +          R  S  PPS      RR  P +
Sbjct: 351 AQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQ 394


>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 100/404 (24%), Positives = 149/404 (36%), Gaps = 51/404 (12%)

Query: 68  EGRSPPGAAASAAA-KPPPLS-AKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAER 125
           E  S P    SA+A +PP LS  KD+    + + G G P  +P   +  E +    +A+R
Sbjct: 28  EALSQPTLRHSASALRPPRLSRGKDL----KPRCGRG-PAHSPDPGEGCEAWR-RLSADR 81

Query: 126 PPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELN---RQSPNPRRGH 182
            PR  S      P A+LA  P  +P P     +P   S +  PP       Q+P    G 
Sbjct: 82  WPRPAS----LSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137

Query: 183 AVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSG-TAAASLGSAQPTDLGAHKRPASV 241
                 + L+N S    P  +       AS A  SG TA     SA P   G  K   S 
Sbjct: 138 CARAKGIRLVNPSPPRPPEPI------PASAAVTSGLTARGPNTSATP---GPQKGRGSA 188

Query: 242 SSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNR 301
             +  +  +++  AA    PPPP        +    G++ LS     +  G G +    R
Sbjct: 189 ERTNHIPKDKQRVAA----PPPPER----PRVPFCRGSSGLSVPTPPEHAG-GRRKKFTR 239

Query: 302 PKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQ 361
            + +  T   L +   + P  +      A       +  R PSP P    G  ++   + 
Sbjct: 240 TRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF-WSPLRNPSPRPAPACGELRLGRLSP 298

Query: 362 PWLST---STEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADN 418
           P   T   S+ G   P +   +  +PP PTA P +     P  A++ + P          
Sbjct: 299 PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGP--------GP 350

Query: 419 AGGSHASKDANQ-----VHSTTRRNSNSPPSPSSMNQRRLGPRE 457
           A G  + +D  +          R  S  PPS      RR  P +
Sbjct: 351 AQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQ 394


>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 100/404 (24%), Positives = 149/404 (36%), Gaps = 51/404 (12%)

Query: 68  EGRSPPGAAASAAA-KPPPLS-AKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAER 125
           E  S P    SA+A +PP LS  KD+    + + G G P  +P   +  E +    +A+R
Sbjct: 28  EALSQPTLRHSASALRPPRLSRGKDL----KPRCGRG-PAHSPDPGEGCEAWR-RLSADR 81

Query: 126 PPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELN---RQSPNPRRGH 182
            PR  S      P A+LA  P  +P P     +P   S +  PP       Q+P    G 
Sbjct: 82  WPRPAS----LSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137

Query: 183 AVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSG-TAAASLGSAQPTDLGAHKRPASV 241
                 + L+N S    P  +       AS A  SG TA     SA P   G  K   S 
Sbjct: 138 CARAKGIRLVNPSPPRPPEPI------PASAAVTSGLTARGPNTSATP---GPQKGRGSA 188

Query: 242 SSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNR 301
             +  +  +++  AA    PPPP        +    G++ LS     +  G G +    R
Sbjct: 189 ERTNHIPKDKQRVAA----PPPPER----PRVPFCRGSSGLSVPTPPEHAG-GRRKKFTR 239

Query: 302 PKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQ 361
            + +  T   L +   + P  +      A       +  R PSP P    G  ++   + 
Sbjct: 240 TRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF-WSPLRNPSPRPAPACGELRLGRLSP 298

Query: 362 PWLST---STEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADN 418
           P   T   S+ G   P +   +  +PP PTA P +     P  A++ + P          
Sbjct: 299 PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGP--------GP 350

Query: 419 AGGSHASKDANQ-----VHSTTRRNSNSPPSPSSMNQRRLGPRE 457
           A G  + +D  +          R  S  PPS      RR  P +
Sbjct: 351 AQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQ 394


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 90/327 (27%), Positives = 112/327 (34%), Gaps = 80/327 (24%)

Query: 107 APRAPQALERYPLAAAAERPPRLGSDFGSSR--PAASLAQPP--TPQPPPVNGILVPNGF 162
           APR P+   R   A A       GS  G++   PAA     P   P+PPP  G   P G 
Sbjct: 44  APRTPEV--RAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPA-GRARPGGG 100

Query: 163 SKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAA 222
                 P      P+PRR       LVP     A P P A  L                 
Sbjct: 101 GPQRPGP------PSPRR------PLVP-----AGPAPPAAKL----------------- 126

Query: 223 SLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAEL 282
                +P   G+    A V ++AAV      AA  E  P  PA      +L+  AG    
Sbjct: 127 -----RPPPEGSAGSCAPVPAAAAV------AAGPEPAPAGPAKPAGPAALAARAGPGPG 175

Query: 283 SAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRK 342
              G G   G G+       +T+  +   L+ H  + P  S     PA       A    
Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA-------ALLPL 228

Query: 343 PSPEPEGEV--GPPKINGEAQPW-LSTSTEGLKIPMTPTSSFVSPP-------------- 385
           P P   G V   PP +   A P   + S      P  P ++   PP              
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPA 288

Query: 386 -PPTASPHSNRTTPPEAAQNGQSPMAA 411
            PPTA+P      PP AAQNG S  AA
Sbjct: 289 GPPTAAP---AVPPPAAAQNGGSAGAA 312



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 104/440 (23%), Positives = 146/440 (33%), Gaps = 63/440 (14%)

Query: 55  TARQLKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEA--APRAPQ 112
           +A  L   H   P         A+    P P +A   ++Q    +G   P A  AP  P 
Sbjct: 201 SAALLNSHHAAAPAVSLVNNGPAALLPLPKP-AAPGTVIQTPPFVGAAAPPAPAAPSPPA 259

Query: 113 ALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELN 172
           A    P A AA  PP   +    +RP    A PPT  P         NG S    P    
Sbjct: 260 APA--PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAP---- 313

Query: 173 RQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQP--T 230
             +P P  G     +  P             G G  AAA    V   +   +  A P   
Sbjct: 314 --APAPAAGGPAGVSGQP-------------GPGAAAAAPAPGVKAESPKRVVQAAPPAA 358

Query: 231 DLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKS 290
              A   PAS ++S  +    + A       PPPA   P      AAGA   S      +
Sbjct: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTA 418

Query: 291 RGSGEQDWVNRPKTVRDTLLA--LHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPE 348
             SG +       T+  T+LA  L Q   +      F+  P +  V   +   +    P+
Sbjct: 419 TTSGIR------ATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLV--RSENGQLLMIPQ 470

Query: 349 GEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSP 408
             +   +    AQP  + +      P TPTS+                 PP      Q+P
Sbjct: 471 QALAQMQAQAHAQPQTTMAPR----PATPTSA-----------------PPVQISTVQAP 509

Query: 409 MAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLG----PREVGGQGAG 464
              +I  A     +   K  +Q  +T + ++    SP    Q  LG       +G   A 
Sbjct: 510 GTPII--ARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAV 567

Query: 465 NTGGLEPVHPASLPDSSLAT 484
            TG  +   P +   SS AT
Sbjct: 568 QTGTPQRTVPGATTTSSAAT 587


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 81/345 (23%), Positives = 125/345 (36%), Gaps = 50/345 (14%)

Query: 78   SAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRA--PQALERYPLAAAAERPPRLGSDFGS 135
            S  AKPPP     +    +Q      P   P A   Q L+  P   A + PP + +    
Sbjct: 845  SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKW 904

Query: 136  SRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGS 195
               +  +  P  P PPP + ++ P        PP     SP P      PPT        
Sbjct: 905  QPSSIPVPSPDFPPPPPESSLVFP-------PPP----PSPVPAPPPPPPPT-------- 945

Query: 196  ATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAA 255
            A+P P   G  G+  +  ++  G          PT     +R +S+ SS+  EH + +  
Sbjct: 946  ASPTPDKSGSPGKKTSKTSSPGGK------KPPPTP----QRNSSIKSSSGAEHPEPKRP 995

Query: 256  AKE---KQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLAL 312
            + +    +  PPA  G     +    AA       GK   SG    VN P  ++   ++ 
Sbjct: 996  SVDSLVSKFTPPAESGSPSKETLPPPAA---PPKPGKLNLSG----VNLPGVLQQGCVSA 1048

Query: 313  HQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLK 372
                   P  S   K+  +   +  +    P P PE E+  P I   A    +TS +   
Sbjct: 1049 -----KAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV 1103

Query: 373  IPMTPTS----SFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALI 413
            +   P      S    PPPT    ++ T   +A  + Q  MA ++
Sbjct: 1104 VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVV 1148



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 72/347 (20%), Positives = 108/347 (31%), Gaps = 59/347 (17%)

Query: 72  PPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGS 131
           P  +A SA +  P       + + Q    H G    P  P  ++   +      PP    
Sbjct: 650 PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN--- 706

Query: 132 DFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQS--PNPRRGHAV----- 184
                     +  PP P PPP  G  +          P L + S  P P + H V     
Sbjct: 707 --------GVVPPPPPPPPPPTPGSAMAQ-LKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757

Query: 185 --PPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVS 242
             PPT  P       P+P  L                       A P  L     P S  
Sbjct: 758 VAPPTPPP-----PPPIPAPLP--------------------PQAPPKPLVTIPAPTSTK 792

Query: 243 SSAAVEHEQREAAAKEKQPP-PPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNR 301
           + A V     +AA     PP PPA + PA   S    +               +Q +  +
Sbjct: 793 TVAPV---VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK 849

Query: 302 P-----KTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKI 356
           P       V   +  +       P     + +P     A  A +  P+ + + +  P  I
Sbjct: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909

Query: 357 NGEAQPWLSTSTEGLKI----PMTPTSSFVSPPPPTASPHSNRTTPP 399
              +  +     E   +    P +P  +   PPPPTASP  +++  P
Sbjct: 910 PVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 14/74 (18%)

Query: 127 PRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVP- 185
           P++ + + +S+P+  L  PP P PPP      P        PP L  QS  P  G A P 
Sbjct: 613 PKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP--------PPPLPSQSA-PSAGSAAPM 663

Query: 186 ----PTLVPLMNGS 195
                T+  L N S
Sbjct: 664 FVKYSTITRLQNAS 677


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 112/485 (23%), Positives = 162/485 (33%), Gaps = 85/485 (17%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERP 126
           P  R  P  +    A+P P    D      ++ G  GP  AP   +  E  P   A   P
Sbjct: 425 PSARDGPERSVPKEAEPTPPVLPD------EEKGPPGP--APEPEREAETEPERGAGTEP 476

Query: 127 PRLGSDFGSSRPAASLAQPPTPQ-------PPPVNGILVPNGFSKLEEPP------ELNR 173
            R+G++  S+ PA S   PP P+            G       +  E PP       L+ 
Sbjct: 477 ERIGTE-PSTAPAPS---PPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDA 532

Query: 174 QSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGG--RAAASLAAVSGTAAASLGSAQPTD 231
           ++  P R  A      P     A P   A   G   R A   +  S  A    G ++P +
Sbjct: 533 EAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLE 592

Query: 232 LGAHKRPASVS-----SSAAVEHEQREAAAKEKQPPPP--AHRGPADSLSTAAGAA--EL 282
             + + P + S     S AA++  Q     +  +P P   A RGP DS   AA  A    
Sbjct: 593 RASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRK 652

Query: 283 SAEGAGKSRGSGE-----------QDWVNRPKTVRDTLLAL-HQHGHSGP------FESK 324
           S + A  + G+ E           +D    P  +R T L+L ++ G S        + ++
Sbjct: 653 SPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAE 712

Query: 325 FKKEPALTAVARTAR-----------KRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKI 373
            + E +LT + +  +            R PS + +G+  PP+      P          +
Sbjct: 713 VRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPP----------L 762

Query: 374 PMTP-TSSFV---SPPPPTASPHSN------RTTPPEAAQNGQSPMAALILVADNAGGSH 423
           P  P   SF     P PP A P         RT      + G             A G  
Sbjct: 763 PRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQP 822

Query: 424 ASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLA 483
           A           R   + PP+       R    E G Q      G EPV  A    S   
Sbjct: 823 APPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSF 882

Query: 484 TSAPL 488
              P+
Sbjct: 883 LITPV 887



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 73/323 (22%), Positives = 107/323 (33%), Gaps = 47/323 (14%)

Query: 166 EEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLG 225
           EE P   +Q   P RG    P           PLP   G   R A    + + TA+   G
Sbjct: 275 EERPSSGQQDVAPDRGPEPGPP---------APLPPPGGARARRARLQHSSALTASVEEG 325

Query: 226 SAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAE 285
                D  +  RPA+   +     E   A     +PP P    P           E    
Sbjct: 326 GVPGEDPSS--RPATPELA-----EPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPA 378

Query: 286 GAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTAR------ 339
           G         ++ V  P+ V          G + P E+    +PA T+ A +AR      
Sbjct: 379 GPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPET----DPAATSEAPSARDGPERS 434

Query: 340 ---KRKPSPE--PEGEVGPP------KINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPT 388
              + +P+P   P+ E GPP      +   E +P     TE  +I   P++   +P P  
Sbjct: 435 VPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPST---APAPSP 491

Query: 389 ASPHSNRTTPPEAAQNGQS---PMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSP 445
            +P S     P AA  G +   P+AA        G      +A          + +PP+ 
Sbjct: 492 PAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPA- 550

Query: 446 SSMNQRRLGPREVGGQGAGNTGG 468
                 R  P     +G     G
Sbjct: 551 ---GAERAAPERKAERGGAELRG 570


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 61/273 (22%), Positives = 97/273 (35%), Gaps = 40/273 (14%)

Query: 71  SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAER----P 126
           SPP    +A+  PPP          ++++ H  P     +P    R P  ++  R    P
Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666

Query: 127 PRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPP 186
            R   +  S +P    +  P P+ P  +             PP     S +P+R  +  P
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSS----------SPPPVRRGASSSPQRRQSPSP 716

Query: 187 TLVPLMNGSATPLPTAL-GLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSA 245
           +  P+   S TP P  +      +  S+  VS + + S GS +P        P+ V S +
Sbjct: 717 STRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS-GSPEPAAKKPPAPPSPVQSQS 775

Query: 246 AVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTV 305
              +       K+ + P P+   P +S            EG GK +           K  
Sbjct: 776 PSTNWSPAVPVKKAKSPTPSPSPPRNS----------DQEGGGKKK-----------KKK 814

Query: 306 RDTLLALHQHGHSGPFESKFKKEPALTAVARTA 338
           +D     H+         K KKE A+ A A  A
Sbjct: 815 KD---KKHKKDKKHKKHKKHKKEKAVAAAAAAA 844



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 82/368 (22%), Positives = 128/368 (34%), Gaps = 56/368 (15%)

Query: 134 GSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQ-SPN---PRRGH--AVPPT 187
           GSS  ++S      P+ PP           +   PP   R+ SP+   PRR H  + P T
Sbjct: 357 GSSSSSSSSRSRSPPKKPP----------KRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406

Query: 188 LVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAV 247
             P    S TP  +      R + S    SG      G+ +        +P  V  S + 
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466

Query: 248 EHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELS------------AEGAGKSRGSGE 295
           E +  + AA +       +R      S+ +G++  S             E   + R S  
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526

Query: 296 QDWVNRP-KTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPP 354
           +     P K  ++T     +     P  ++ ++ P+     R  R   P P       PP
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586

Query: 355 KINGEAQPWLSTSTEGLKIPMTPTSS-FVSPPPP---TASP------HSNRTTPPEAAQN 404
           +    +    S   +    P  P      SPPPP    ASP        + + PP+   +
Sbjct: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS 646

Query: 405 GQSPMAALILVADNAGGSHASKDA--------NQVHSTTRR-----NSNSPP----SPSS 447
             +   +  L + +  GS  S+          N+ HS + R      S+SPP      SS
Sbjct: 647 PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS 706

Query: 448 MNQRRLGP 455
             QRR  P
Sbjct: 707 SPQRRQSP 714



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 62/289 (21%), Positives = 89/289 (30%), Gaps = 31/289 (10%)

Query: 118 PLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPN 177
           P     E  PR       S P     + P+P PPP           +    P   R+SP+
Sbjct: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPS 592

Query: 178 PRRGHAVPP------TLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSA---- 227
           PRR    PP         P    +A+P P        +      VS +      S+    
Sbjct: 593 PRR--YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650

Query: 228 --QPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAE 285
              P+    H++ +S S S     E R     ++  P P  R P  S S        S+ 
Sbjct: 651 RRSPSLSSKHRKGSSPSRST---REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS 707

Query: 286 GAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSP 345
              +   S     + R     +            P + K    P+  +V R +  R  S 
Sbjct: 708 PQRRQSPSPSTRPIRRVSRTPE------------PKKIKKAASPSPQSVRRVSSSRSVSG 755

Query: 346 EPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSN 394
            PE     P       P  S S      P  P     SP P  + P ++
Sbjct: 756 SPEPAAKKPP--APPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 33/208 (15%)

Query: 252 REAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLA 311
           R      + PPPP HR    S S        SA  +G S  S      + PK        
Sbjct: 324 RRRTPPRRMPPPPRHR---RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT-- 378

Query: 312 LHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGL 371
                 S P     +  P   + +   R+ +PSP       PPK      P  S  T   
Sbjct: 379 ------SSPPRKTRRLSP---SASPPRRRHRPSPP---ATPPPKTRHSPTPQQSNRTRKS 426

Query: 372 KIPMTP--TSSFVSPPPPTASPHSNRTTP-PEAAQNGQSPMAALILVADNAGGSHASKDA 428
           ++ ++P  TS  V+    T    S    P P   +  +S         ++ GG  A+ D+
Sbjct: 427 RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSES--------EEDKGGKMAAADS 478

Query: 429 NQVHSTTRR-----NSNSPPSPSSMNQR 451
            Q     RR     +S+S  S SS ++R
Sbjct: 479 VQQRRQYRRQNQQSSSDSGSSSSSEDER 506


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 84/327 (25%), Positives = 111/327 (33%), Gaps = 46/327 (14%)

Query: 44   EGADRVEFVIE-TARQLKRAHGCFPEG-RSPPGAAASAAAKPPPLSAKDILLQQQQQLGH 101
            E AD   FV + T RQ  R       G   PP A   A+A            Q+  +   
Sbjct: 1083 ESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFIL 1142

Query: 102  GGPEAAPRAPQALERYPLAAAAERPPRL-----GSDFGSSRPAASLAQPPTPQPPPVNGI 156
               +   R P+A ER    A  E PP L     G+     RPA+  A PP   PPP    
Sbjct: 1143 TESDTVKRRPKAKER---EAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAE 1199

Query: 157  LVPNGFSKLEEPPELNRQSPNPRRGHAVP-PTL---VPLMNGSATPLPTALGLGGRAAAS 212
              P   + L   P    ++  P +    P P L   VP + GS TP    + L G  +  
Sbjct: 1200 PPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPE 1259

Query: 213  LAAVSGT-------------------AAASL--GSA--QPTDLGAHKRPASVSSSAAVEH 249
            +    GT                   A A L  GSA   P    A + PA+++       
Sbjct: 1260 VKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPP 1319

Query: 250  EQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTL 309
                + AK   P  PA   PA     AA AA  +A       G+   D   +        
Sbjct: 1320 SLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSAC 1379

Query: 310  LA---------LHQHGHSGPFESKFKK 327
            LA         + Q    GP +S  +K
Sbjct: 1380 LAAALQAVEEKIRQEDAQGPRDSAAEK 1406



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 53/211 (25%), Positives = 77/211 (36%), Gaps = 18/211 (8%)

Query: 72   PPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGS 131
            PP   A   AKPP +S K +L Q   +L  G P    +      + PL       P +  
Sbjct: 1213 PPEGEARKPAKPP-VSPKPVLTQPVPKL-QGSPTPTSK------KVPLPGPGS--PEVKR 1262

Query: 132  DFGSSRPAASLAQPPTPQPPPVNGIL-VPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVP 190
              G+  P +    PP   P PV  +  +P+G +     P   RQ P      A PP   P
Sbjct: 1263 AHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPP---AALAKPPGTPP 1319

Query: 191  LMNGSATPLPT----ALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAA 246
             +  S    P+    AL +  +   + AA +  AAA     +    G   R     +SA 
Sbjct: 1320 SLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSAC 1379

Query: 247  VEHEQREAAAKEKQPPPPAHRGPADSLSTAA 277
            +    +    K +Q      R  A   ST +
Sbjct: 1380 LAAALQAVEEKIRQEDAQGPRDSAAEKSTGS 1410



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 83/389 (21%), Positives = 125/389 (32%), Gaps = 56/389 (14%)

Query: 126  PPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVP 185
            PP+  S   S+  +A+LA  P P   P +G+L                     RR   + 
Sbjct: 949  PPKRSS---SALASANLADEPVPDAEPEDGLLGVRA---------------QCRRASDLA 990

Query: 186  PTLVPLMNGSATPLPTAL---GLGGRAAASLAAVSGTAAASLGSAQP----TDLGAHKRP 238
             ++     GS   +   L    +GG   A+     G       S +P    T L + K  
Sbjct: 991  GSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHK 1050

Query: 239  ASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGE--- 295
             ++     V + +R  +         A RGP +S    A       +G G+ R  G    
Sbjct: 1051 EAIGPGGEVVNRRRTLSGPVTGLLATARRGPGES----ADPGPFVEDGTGRQRPRGPSKG 1106

Query: 296  QDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPK 355
            +  V  P   +    A  +         +   +  LT      R+ K      G   PP 
Sbjct: 1107 EAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPP 1166

Query: 356  I----NGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEA-----AQNGQ 406
            +    NG        ++E    P  P     + PPPT   H     PPE      A+   
Sbjct: 1167 LSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPV 1226

Query: 407  SPMAALILVADNAGGS------------HASKDANQVHSTTRRNSNSPPSPSSMNQRRLG 454
            SP   L        GS              S +  + H T    S  PP P +  +    
Sbjct: 1227 SPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPK---P 1283

Query: 455  PREVGGQGAGNTGGLEPVHPASLPDSSLA 483
             + V G  +G+ G      PA  P ++LA
Sbjct: 1284 VKAVAGLPSGSAGPSPAPSPARQPPAALA 1312



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 104/437 (23%), Positives = 146/437 (33%), Gaps = 90/437 (20%)

Query: 104  PEAAPRAPQALERYPL--AAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNG 161
            P   P +P++L + P     A   P  +  + G   PAA     P P PPPV     P  
Sbjct: 813  PTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVG---PAA-----PGPAPPPV-----PTA 859

Query: 162  FSKLEEPPELNRQSPNPR-RGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTA 220
               L  PPE + +   P+ R H+    L       + P    L L   AA   A V    
Sbjct: 860  VPTLCLPPEADAEPGRPKKRAHS----LNRYAASDSEPERDEL-LVPAAAGPYATVQRRV 914

Query: 221  AASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAA 280
              S     P   GA K   + S S AV         ++K PPPP  +  + +L++A  A 
Sbjct: 915  GRSHSVRAPA--GADKN-VNRSQSFAVR-------PRKKGPPPPPPKRSSSALASANLAD 964

Query: 281  E---------------LSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSG------ 319
            E                    A    GS +       K++   +L L   G  G      
Sbjct: 965  EPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIA-AMLELSSIGGGGRAARRP 1023

Query: 320  ----PFESKFKKEPALTAVARTARKRKPSPEPEGEV--------GP-----------PKI 356
                P       EP   A    + K K +  P GEV        GP           P  
Sbjct: 1024 PEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGE 1083

Query: 357  NGEAQPWLSTSTEGLKIPMTPTSSFVS-PPPPTASPHSNRTTPP--EAAQNGQSPMAALI 413
            + +  P++   T G + P  P+        PP A   ++ T      A QN Q  +  ++
Sbjct: 1084 SADPGPFVEDGT-GRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFIL 1142

Query: 414  LVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGP--REVGGQGAGNTGGLEP 471
              +D       +K+        R     PP P S+     G   R    + AG      P
Sbjct: 1143 TESDTVKRRPKAKE--------REAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPP 1194

Query: 472  VHPASLPDSSLATSAPL 488
              PA  P + LA   PL
Sbjct: 1195 PPPAEPPPTDLAHLPPL 1211


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 85/356 (23%), Positives = 123/356 (34%), Gaps = 50/356 (14%)

Query: 148 PQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSAT---------- 197
           P PP     +VP G     EPP  + ++ +   G  VP +   L  G +           
Sbjct: 526 PLPPTDGSTVVPAG----PEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKD 581

Query: 198 PLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAK 257
           P+  A+   GR  + +A+      A+ GS Q   +G     A  S        ++ A A 
Sbjct: 582 PVSAAVPAPGRNNSQIASGQNQPQAAAGSHQ-LSMGQPHNAAGPSPHTLRRAVKKPAPAP 640

Query: 258 EKQP-PPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRP--KTVRDTLLALHQ 314
            K   PPP H G   S  T+     LS +   +S     Q     P   +    L A  +
Sbjct: 641 PKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRR 700

Query: 315 HGHS-GPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKI 373
           +  S  P ++     P     A      KP+ +     GPP       P    S  GL+ 
Sbjct: 701 YSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQ-----GPPN------PMALPSEHGLEQ 749

Query: 374 PMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHS 433
           P          PP T +P S   TPP   QN   P    +     AGG   + +  Q H+
Sbjct: 750 PS-------HTPPQTPTPPS---TPPLGKQNPSLPAPQTL-----AGG---NPETAQPHA 791

Query: 434 TTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTG--GLEPVHPASLPDSSLATSAP 487
            T       P P +       P+  G   AG++      P     + DS+   S P
Sbjct: 792 GTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEP 847



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 14/157 (8%)

Query: 72  PPG--AAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRL 129
           PPG  +A S  + P   S+    L   Q   H  P+   +A   +   P +     P  L
Sbjct: 685 PPGQPSAPSQLSAPRRYSSS---LSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMAL 741

Query: 130 GSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHA--VP-- 185
            S+ G  +P+ +  Q PTP   P  G   P+    L  P  L   +P   + HA  +P  
Sbjct: 742 PSEHGLEQPSHTPPQTPTPPSTPPLGKQNPS----LPAPQTLAGGNPETAQPHAGTLPRP 797

Query: 186 -PTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAA 221
            P   P    S  P P   G+     +SL   + TA+
Sbjct: 798 RPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTAS 834



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 8/153 (5%)

Query: 341 RKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKI-PMTPTSSFVSPPPPTASPHSNRTTPP 399
           +KP+P P     PP  +   Q    TS     + P  PT S   P   T  P    + P 
Sbjct: 634 KKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPS 693

Query: 400 EAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVG 459
           + +   +   +   + A N         A  +   T+ NS  PP+P ++      P E G
Sbjct: 694 QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPL-MHTKPNSQGPPNPMAL------PSEHG 746

Query: 460 GQGAGNTGGLEPVHPASLPDSSLATSAPLCCTL 492
            +   +T    P  P++ P      S P   TL
Sbjct: 747 LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTL 779


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 102/447 (22%), Positives = 139/447 (31%), Gaps = 65/447 (14%)

Query: 70  RSPPGAAAS--AAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPP 127
           RS  GA A+    A  PP  A+   +  + +L  G  + A RAP+A +    AA A+R  
Sbjct: 358 RSQLGARANEGGGAPRPPAGARVFGVWARGRLRRGCHKCADRAPRAPKAAAKAAPAKRTA 417

Query: 128 RLGSDFGSSRPA----ASLAQPPTPQPP---PVNGILVPNGFSKLEEPPELNRQSPNPRR 180
           R       + PA    A  A+P  P  P    V  IL PN F+        +R+      
Sbjct: 418 RRRXXXXDTVPAAPEGAGAARPAAPLRPTSFSVLDILDPNKFN--------SRRRRCVLL 469

Query: 181 GHAVPPTLVPLMNGSATPLPTALGLGGRA-AASLAAVSGTAAASLGSAQPTDLG------ 233
           G   P    P  +    P P A G   RA      A++G        A+P + G      
Sbjct: 470 GPVAPAACAPCASAPCAPAPAASGRPPRAEELERRALAGAGGVGAAGAEPPNAGDPFKAG 529

Query: 234 -AHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAG-KSR 291
            A     +  SS    H     +  E           A     A GA E    G G  +R
Sbjct: 530 EAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGAR 589

Query: 292 GSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEV 351
           GSG Q                          ++    P  T     A    P P     V
Sbjct: 590 GSGCQG------------------------AAETDASPGATVDEAAA----PGPRENSPV 621

Query: 352 GPPKINGEAQP-WLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTT---PPEAAQNGQS 407
            P    G A P    T+ +G      P          +  P   RT        A   + 
Sbjct: 622 APGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKF 681

Query: 408 PMAALILVAD--NAGGSHASKDAN-----QVHSTTRRNSNSPPSPSSMNQRRLGPREVGG 460
                + V +  N   S +  +       Q   T  +  N     S+      GP    G
Sbjct: 682 KATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAG 741

Query: 461 QGAGNTGGLEPVHPASLPDSSLATSAP 487
            G G  GGL P+ P+    + L    P
Sbjct: 742 PGTGLPGGLSPLSPSPPMGAPLGMHGP 768


>gi|217416343 fibrosin-like 1 [Homo sapiens]
          Length = 1045

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/303 (26%), Positives = 112/303 (36%), Gaps = 61/303 (20%)

Query: 118 PLAAAAERPPRLGSDFGSSRPAASLA--QPPTPQPPPVNGILVPNGFSKLEEP-PELNRQ 174
           P  +  ER   L ++  S  P AS A    P P PPP +     N   K E P P  +  
Sbjct: 245 PKVSGLERSRELSAE--SFLPTASPAPHAAPCPGPPPGSR---ANPLVKKEPPAPHRHTP 299

Query: 175 SPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLG-----SAQP 229
            P P +   + PT VP   G+        G    AA  L  +S +++A LG     S  P
Sbjct: 300 QPPPPQPRGLLPTHVPASLGAFA------GHSQAAANGLHGLSRSSSAPLGLGKHVSLSP 353

Query: 230 TDLGAHKRPASVSSSAAVEHEQREA--AAKEKQPPPPAHRGPADSLSTAAGAAE------ 281
              G H   + ++  +  +H+   A  AA    PPPPA   PA SL      A+      
Sbjct: 354 HGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPAL--PASSLVLPGHPADHELLRQ 411

Query: 282 --------LSAEGAGKSRGSG---EQDWVNRPKTVRDTLLALHQHGHS-GPFESKFKKEP 329
                    SAE  G S G G     ++     T + T    HQH H+  PF +     P
Sbjct: 412 ELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTP 471

Query: 330 ALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTA 389
                        P+  P  +   PK++    P+   S+    +   P+     P  PT 
Sbjct: 472 -------------PAAPPPFDKYAPKLD---SPYFRHSS----VSFFPSFPPAIPGLPTL 511

Query: 390 SPH 392
            PH
Sbjct: 512 LPH 514



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 38/121 (31%), Positives = 46/121 (38%), Gaps = 18/121 (14%)

Query: 60   KRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPR-APQALERYP 118
            +  HG  PE        A A   PP   A D  L     L   G    PR +P AL    
Sbjct: 931  REPHGYSPERLRGELERARAPHLPPAAPALDGAL-----LPSLGALHFPRLSPAALHNGL 985

Query: 119  LAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVN-----GILVP---NGFSKLEEPPE 170
            LA    R P   +  G+  P  + A PPTP  PP +     G L P     +S    PPE
Sbjct: 986  LA----RTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPE 1041

Query: 171  L 171
            +
Sbjct: 1042 V 1042


>gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo
           sapiens]
          Length = 334

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 52/170 (30%), Positives = 68/170 (40%), Gaps = 33/170 (19%)

Query: 146 PTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGL 205
           P    PP   +    G + L     L R+ P  R G   PP LVP+      PL T L L
Sbjct: 128 PRRHAPPRKQLRGRRGAAGLVSAGHLGREPP--RGGGLRPPALVPV------PLATPLLL 179

Query: 206 GGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPA------------SVSSSAAVEHEQRE 253
            GR+  S      T A ++   Q   LGAH RPA               ++A    + R 
Sbjct: 180 EGRSEPS------TRACAVSGGQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRG 233

Query: 254 AAAKEKQPPPPAHRGPADSLSTAAGAAELSAEG-------AGKSRGSGEQ 296
           AAA  ++PP    R PA   +  A  A L A G       A ++R  GE+
Sbjct: 234 AAAGPERPPHVQGRRPAPRGAVGARRALLGAVGKAGGLTRARETRRRGEE 283


>gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo
           sapiens]
          Length = 329

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 52/170 (30%), Positives = 68/170 (40%), Gaps = 33/170 (19%)

Query: 146 PTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGL 205
           P    PP   +    G + L     L R+ P  R G   PP LVP+      PL T L L
Sbjct: 123 PRRHAPPRKQLRGRRGAAGLVSAGHLGREPP--RGGGLRPPALVPV------PLATPLLL 174

Query: 206 GGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPA------------SVSSSAAVEHEQRE 253
            GR+  S      T A ++   Q   LGAH RPA               ++A    + R 
Sbjct: 175 EGRSEPS------TRACAVSGGQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRG 228

Query: 254 AAAKEKQPPPPAHRGPADSLSTAAGAAELSAEG-------AGKSRGSGEQ 296
           AAA  ++PP    R PA   +  A  A L A G       A ++R  GE+
Sbjct: 229 AAAGPERPPHVQGRRPAPRGAVGARRALLGAVGKAGGLTRARETRRRGEE 278


>gi|239508758 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 52/170 (30%), Positives = 68/170 (40%), Gaps = 33/170 (19%)

Query: 146 PTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGL 205
           P    PP   +    G + L     L R+ P  R G   PP LVP+      PL T L L
Sbjct: 123 PRRHAPPRKQLRGRRGAAGLVSAGHLGREPP--RGGGLRPPALVPV------PLATPLLL 174

Query: 206 GGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPA------------SVSSSAAVEHEQRE 253
            GR+  S      T A ++   Q   LGAH RPA               ++A    + R 
Sbjct: 175 EGRSEPS------TRACAVSGGQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRG 228

Query: 254 AAAKEKQPPPPAHRGPADSLSTAAGAAELSAEG-------AGKSRGSGEQ 296
           AAA  ++PP    R PA   +  A  A L A G       A ++R  GE+
Sbjct: 229 AAAGPERPPHVQGRRPAPRGAVGARRALLGAVGKAGGLTRARETRRRGEE 278


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 108/456 (23%), Positives = 156/456 (34%), Gaps = 85/456 (18%)

Query: 83   PPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERY---PLAAAAERPPRLGSDFGSSRPA 139
            PPP    D    Q   L H  P   P  P+AL  +   P    +   P L      S  +
Sbjct: 951  PPPPPVTDC--SQGSPLPHS-PVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVS 1007

Query: 140  ASLAQP--PTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSAT 197
              L  P  P+ +PPP   +     F K   PP  N   P   RG   PP+     +    
Sbjct: 1008 LPLPPPLLPSSEPPPAPPL--DPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPM 1065

Query: 198  PLPTALGLGGRAAASLAAVSGTAAASLG--SAQ----PTDLGAHKRPA----SVSSSAAV 247
            PL T   L       +   SG  AA L   +AQ    P     H +P+    S +S+  +
Sbjct: 1066 PLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEM 1125

Query: 248  EHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRD 307
            E E + A+     P P       D  S A     +S      S G               
Sbjct: 1126 ESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAG--------------- 1170

Query: 308  TLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGE-----VGPPKINGEAQP 362
                          E++ +  P+ T +  ++  RKP P  +       V PP+ +   +P
Sbjct: 1171 --------------EAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEP 1216

Query: 363  WLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGS 422
              + S E L+   +PT+          S HS       AAQ G          A + G S
Sbjct: 1217 AENVS-EALRAVPSPTTG------EEGSVHSREAKESSAAQAGSH--------ATHPGTS 1261

Query: 423  HASKDANQVHSTTRRNSNSPPSPSSMNQRRLGP---REVGGQGAGNTGG------LEPVH 473
                 A    S +R  +N P     M Q  + P   +E   + + +TGG       +   
Sbjct: 1262 VLEGGAAGSMSPSRVEANVP-----MVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDG 1316

Query: 474  PASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVP 509
             A +P+++ A S+   C    E   D   V  PS P
Sbjct: 1317 AAGVPETNAAGSSSEACDFLKEDGNDE--VMTPSRP 1350



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 87/367 (23%), Positives = 132/367 (35%), Gaps = 62/367 (16%)

Query: 68   EGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPP 127
            E  S P +  S+   P   S++            GGP +  R+P A    P A  AE  P
Sbjct: 1126 ESESQPASVTSSLPTPAKSSSQG---DHGSAAERGGPVS--RSPGA----PSAGEAEARP 1176

Query: 128  RLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPT 187
               S   +  P +S    P+ +PPP++            + P+L    P P++  AV P 
Sbjct: 1177 ---SPSTTPLPDSS----PSRKPPPIS------------KKPKLFLVVPPPQKDFAVEPA 1217

Query: 188  LVPLMNGSATPLPTALGLGG----RAAASLAAVSGTAAASLG-SAQPTDLGAHKRPASVS 242
                    A P PT    G      A  S AA +G+ A   G S           P+ V 
Sbjct: 1218 ENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVE 1277

Query: 243  SSAAVEHEQREAAAKEKQPPPPAHRGPADSLST------AAGAAELSAEGAG-------K 289
            ++  +       A K+++P   +     D  S       AAG  E +A G+        K
Sbjct: 1278 ANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLK 1337

Query: 290  SRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSP--EP 347
              G+ E    +RP+T  D   A+H+        SK K      +    +R   PSP   P
Sbjct: 1338 EDGNDEVMTPSRPRTTEDLFAAIHR--------SKRKVLGRRDSDDDHSRNHSPSPPVTP 1389

Query: 348  EG---EVGPPKINGEAQPWL---STSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEA 401
             G    +  PK  G  Q  +   STS++  K  +    S        ++    + T P  
Sbjct: 1390 TGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRF 1449

Query: 402  AQNGQSP 408
             ++   P
Sbjct: 1450 QRSRSEP 1456


>gi|239754516 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 334

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 52/170 (30%), Positives = 68/170 (40%), Gaps = 33/170 (19%)

Query: 146 PTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGL 205
           P    PP   +    G + L     L R+ P  R G   PP LVP+      PL T L L
Sbjct: 128 PRRHAPPRKQLRGRRGAAGLVSAGHLGREPP--RGGGPRPPALVPV------PLATPLLL 179

Query: 206 GGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPA------------SVSSSAAVEHEQRE 253
            GR+  S      T A ++   Q   LGAH RPA               ++A    + R 
Sbjct: 180 EGRSEPS------TRACAVSGRQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRG 233

Query: 254 AAAKEKQPPPPAHRGPADSLSTAAGAAELSAEG-------AGKSRGSGEQ 296
           AAA  ++PP    R PA   +  A  A L A G       A ++R  GE+
Sbjct: 234 AAAGPERPPHVQGRRPAPRGAVGARRALLGAVGKAGGLTRARETRRRGEE 283


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 82/372 (22%), Positives = 120/372 (32%), Gaps = 20/372 (5%)

Query: 67  PEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERP 126
           P     P     A   PPP      +    + LG     +A +AP  ++  P   A E  
Sbjct: 353 PSAEESPSEEPPAEILPPPAEKSPSV----ELLGEIRSPSAQKAPIEVQPLPAEGALEEA 408

Query: 127 PRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPE---LNRQSPNPRRGHA 183
           P            A + QP  P+  P          + +E P E      QSP P+   A
Sbjct: 409 PAKVEPPTVEETLADV-QPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTA 467

Query: 184 VPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSS 243
              +    +  +  P         R+  S    +  A A + S    +  A +  A +  
Sbjct: 468 EEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQL 527

Query: 244 SAAVEHEQREAAAKEKQP---PPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVN 300
            AA+E    E  A+ + P      A   PA+  S +A    +          SGE+    
Sbjct: 528 LAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAE 587

Query: 301 RPKTVRDTLLALHQHGHSGPFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKIN--- 357
                   L A        P E   +  PA  A A    +  P+ E   EV PP      
Sbjct: 588 EASAAIQLLAATEASAEEAPAE--VQPPPAEEAPAEV--QPPPAEEAPAEVQPPPAEEAP 643

Query: 358 GEAQPWLSTST--EGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILV 415
            E QP  +     E    P     + V PPP   +P   ++ P E     ++  A     
Sbjct: 644 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPP 703

Query: 416 ADNAGGSHASKD 427
           AD+     AS D
Sbjct: 704 ADDVPAEEASVD 715


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/219 (28%), Positives = 78/219 (35%), Gaps = 26/219 (11%)

Query: 72  PPGAAASAAAKPPPL-SAKDILLQQQQQLG-------HGGPEAAPRAPQALERYPLAAAA 123
           PPG  A+A   P P+ S+K     +++ L        H G E  P  P            
Sbjct: 181 PPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPV---------- 230

Query: 124 ERPPRLGSDFGSSRPAASLAQPPTP--QPPPV-NGILVPNGFSKLEEPPE---LNRQSPN 177
            +PP    +  +     SLA PP P  QPP V NG   P   S  E P     L+R++P 
Sbjct: 231 -KPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPG 289

Query: 178 PRRGHAVPP-TLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHK 236
           P RG A PP T       S  P P A     R AA           +  +  P       
Sbjct: 290 PVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMH 349

Query: 237 RPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLST 275
                S         R  A     PPPP   G  DS++T
Sbjct: 350 GSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITT 388



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 95/386 (24%), Positives = 132/386 (34%), Gaps = 89/386 (23%)

Query: 47  DRVEFVIETARQLKRAHGCFPEGRSPPGAAASAAA-KPPPLSAKDILLQQQQQLGHGGPE 105
           DR   ++E  +     +G       P G        K  P+ AKD      + L      
Sbjct: 58  DRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKD----GSENLAGKPAL 113

Query: 106 AAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKL 165
             P +  A  R P++AA+ RP     D  SSR  ASL + P  Q P +  +  PN  S  
Sbjct: 114 QIPSSRAAAPRPPVSAASGRPQ---DDTDSSR--ASLPELPRMQRPSLPDLSRPNTTSST 168

Query: 166 EEPPELNRQSPNP--RRGHAVPPTLVPLMNGSAT------PLPTALGLG---GRAA---- 210
                 +   P P  RR +A PPT +P+ +  A       PLP   G     GR      
Sbjct: 169 GMKHSSSAPPPPPPGRRANA-PPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAP 227

Query: 211 -------ASLAAVSGTAAASLGSAQPT---DLGAHKRPASVSSSAAVEHEQREAAAKEKQ 260
                  + +   +G +  SL    P      G    P+S ++ +A E  QR  +   K 
Sbjct: 228 PPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKT 287

Query: 261 PPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKT-VRDTLLALHQHGHSG 319
           P P   RG A    T+A  + LS                NRP    RD            
Sbjct: 288 PGPV--RGLAPPPPTSASPSLLS----------------NRPPPPARDP----------- 318

Query: 320 PFESKFKKEPALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTS 379
              S+    P    V R   +  P P P     P +++G   P                S
Sbjct: 319 --PSRGAAPPPPPPVIRNGARDAPPPPP-----PYRMHGSEPP----------------S 355

Query: 380 SFVSPPPPTASPHSNRTTPPEAAQNG 405
               PPPP+ +P      PP   +NG
Sbjct: 356 RGKPPPPPSRTPAGPPPPPPPPLRNG 381



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 65/276 (23%), Positives = 93/276 (33%), Gaps = 36/276 (13%)

Query: 186 PTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSA 245
           P L    + +A P P      GR      + S  +   L   Q   L    RP + +SS 
Sbjct: 111 PALQIPSSRAAAPRPPVSAASGRPQDDTDS-SRASLPELPRMQRPSLPDLSRP-NTTSST 168

Query: 246 AVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTV 305
            ++H     ++    PPPP  R  A        +++  A               NR K +
Sbjct: 169 GMKH-----SSSAPPPPPPGRRANAPPTPLPMHSSKAPA--------------YNREKPL 209

Query: 306 RDTLLALHQHGHSGPFESKFKKEPALTAVARTA---RKRKPSPEPEGEV-----GPPKIN 357
             T       G  GP      K P      RT    +   P P P  +      GP    
Sbjct: 210 PPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPT 269

Query: 358 GEAQPWLSTSTEGL--KIPMTPTSSFVSPPPPTASPH--SNRTTPP--EAAQNGQSPMAA 411
            E+ P L      L  K P  P      PPP +ASP   SNR  PP  +    G +P   
Sbjct: 270 NESAPELPQRHNSLHRKTP-GPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPP 328

Query: 412 LILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSS 447
             ++ + A  +       ++H +   +   PP P S
Sbjct: 329 PPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPS 364


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,710,736
Number of Sequences: 37866
Number of extensions: 1863707
Number of successful extensions: 15534
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 1147
Number of HSP's that attempted gapping in prelim test: 11056
Number of HSP's gapped (non-prelim): 4551
length of query: 571
length of database: 18,247,518
effective HSP length: 108
effective length of query: 463
effective length of database: 14,157,990
effective search space: 6555149370
effective search space used: 6555149370
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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