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Search of human proteins with 116534898
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
(1118 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 2215 0.0
gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 626 e-179
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 615 e-176
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 610 e-174
gi|119703744 desmoglein 1 preproprotein [Homo sapiens] 548 e-155
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 337 3e-92
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 336 6e-92
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 327 3e-89
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 326 9e-89
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 323 4e-88
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 320 4e-87
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 300 5e-81
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 298 1e-80
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 294 4e-79
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 278 2e-74
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 255 2e-67
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 253 7e-67
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 239 8e-63
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 215 2e-55
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 215 2e-55
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 202 1e-51
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 199 2e-50
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 196 8e-50
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 187 6e-47
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 184 5e-46
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 183 9e-46
gi|16753221 cadherin 22 precursor [Homo sapiens] 173 9e-43
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 172 2e-42
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 168 3e-41
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 167 4e-41
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 2215 bits (5740), Expect = 0.0
Identities = 1118/1118 (100%), Positives = 1118/1118 (100%)
Query: 1 MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALRE 60
MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALRE
Sbjct: 1 MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALRE 60
Query: 61 GEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDRE 120
GEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDRE
Sbjct: 61 GEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDRE 120
Query: 121 ETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMK 180
ETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMK
Sbjct: 121 ETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMK 180
Query: 181 INATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVE 240
INATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVE
Sbjct: 181 INATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVE 240
Query: 241 ARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADE 300
ARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADE
Sbjct: 241 ARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADE 300
Query: 301 IGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAF 360
IGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAF
Sbjct: 301 IGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAF 360
Query: 361 HKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDT 420
HKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDT
Sbjct: 361 HKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDT 420
Query: 421 GLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKT 480
GLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKT
Sbjct: 421 GLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKT 480
Query: 481 ITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGM 540
ITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGM
Sbjct: 481 ITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGM 540
Query: 541 AEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCR 600
AEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCR
Sbjct: 541 AEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCR 600
Query: 601 EAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNE 660
EAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNE
Sbjct: 601 EAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNE 660
Query: 661 GAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEE 720
GAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEE
Sbjct: 661 GAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEE 720
Query: 721 HRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKA 780
HRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKA
Sbjct: 721 HRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKA 780
Query: 781 ASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVC 840
ASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVC
Sbjct: 781 ASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVC 840
Query: 841 LGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAE 900
LGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAE
Sbjct: 841 LGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAE 900
Query: 901 KVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQS 960
KVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQS
Sbjct: 901 KVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQS 960
Query: 961 LIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERE 1020
LIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERE
Sbjct: 961 LIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERE 1020
Query: 1021 SFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAG 1080
SFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAG
Sbjct: 1021 SFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAG 1080
Query: 1081 VPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS 1118
VPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS
Sbjct: 1081 VPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS 1118
>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
Length = 999
Score = 626 bits (1614), Expect = e-179
Identities = 386/1008 (38%), Positives = 577/1008 (57%), Gaps = 71/1008 (7%)
Query: 1 MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALRE 60
M P AL + ++ V L ++ +E ++ + RQKR W+ RE
Sbjct: 2 MGLFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKR-RQKREWVKFAKPCRE 60
Query: 61 GEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDRE 120
GED SK+NPIAKI SD + KITY+ +G GI +PPFGIFV +K+TG++N+T+I+DRE
Sbjct: 61 GEDNSKRNPIAKITSDYQATQ--KITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDRE 118
Query: 121 ETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMK 180
ETP FL+T AL+A+G +VEKPL L +K+LDINDN PVF+Q +F+G +EE SA+++LVM
Sbjct: 119 ETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMI 178
Query: 181 INATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVE 240
+NATDADEPN LNSKI+++IVS EPA P+F L+++TGE+ T + +LDRE+ SSY L V
Sbjct: 179 LNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVS 238
Query: 241 ARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADE 300
D +GE Q + I++ DVNDN P+ + +EEN ++ E+ R +V D DE
Sbjct: 239 GADKDGEGLS---TQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDE 295
Query: 301 IGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAF 360
+DNWLA + F SGNEG +F I+TD +TNEGI+ ++K +DYE+++++ S+ V NKA F
Sbjct: 296 EYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEF 355
Query: 361 HKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESM-DRSSKGQIIGNFQAFDED 419
H+S+ S+Y+ P+ ++V NV+EGI F+ + + V + + + I+G +QA DED
Sbjct: 356 HQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDED 415
Query: 420 TGLPA-HARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPR 478
T A + +YV + ++ +DS T+EIK K + +S ++ N T T +++AI E Y
Sbjct: 416 TNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDE-YTG 474
Query: 479 KTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPP 538
KT TGTV + V D NDNCPT + +C + V V+A L+ +GP++F++ D+P
Sbjct: 475 KTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNNR-YTGPYTFALEDQPV 533
Query: 539 GMAEKWKIARQESTSVLLQQSEK-KLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGS 597
+ W I +TS LL+ E+ G I +++D+Q C + LTL VC+C +
Sbjct: 534 KLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRG 593
Query: 598 GCREAQHDSYVG----------LGPAAIALMILAFLLLLLVPLLLLMCHCGKGAK----- 642
C + + G LGPAAI L++L LLLLL PLLLL C CG G+
Sbjct: 594 ICGTSYPTTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTGGVTG 653
Query: 643 GFTPIP-GTIEMLHPWNNEGAPPEDKVVPSFL--PVDQGGSLVGRNG---VGGMAKEATM 696
GF P+P G+ +H W EGA PEDK + + PV G+ + A+ +
Sbjct: 654 GFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTANGADFMESSEVCTNTYARGTAV 713
Query: 697 KGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTE----TTKTARAT- 751
+G+S + +E G +SG A+ F ATG + + T +T +T
Sbjct: 714 EGTSGMEMTTKLGAATESGGAAGFATGTVSGAASGFGAATGVGICSSGQSGTMRTRHSTG 773
Query: 752 GASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNA-- 809
G ++D A A++ FL +YF+ KA + EED+ A DCLL+Y E ++ +
Sbjct: 774 GTNKDYADG-----AISMNFLDSYFSQKAFACAEEDDGQEANDCLLIYDNEGADATGSPV 828
Query: 810 -SIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATET--SMNTA 866
S+GCCSFI +LDD FLD LG KFK LAE+ LG ++ E ++ Q P+ ++ + +
Sbjct: 829 GSVGCCSFIADDLDDSFLDSLGPKFKKLAEISLG----VDGEGKEVQPPSKDSGYGIESC 884
Query: 867 SHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPD 926
H + Q + SGS Q A+A +S+ + + A +PD
Sbjct: 885 GHPIEVQQTGFVKCQTLSGS--------QGASA------------LSTSGSVQPAVSIPD 924
Query: 927 PMASRNVIATETSYVTGSTMPPTTVILGPSQPQSLIVTERVYAPASTL 974
P+ N + TET +GS + P+T P Q++IVTERV P S++
Sbjct: 925 PLQHGNYLVTETYSASGSLVQPSTAGFDPLLTQNVIVTERVICPISSV 972
Score = 34.7 bits (78), Expect = 0.52
Identities = 19/47 (40%), Positives = 29/47 (61%)
Query: 1020 ESFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTE 1066
E++ A S VQP+ A + + QNV VTERV+ P S++ + PT+
Sbjct: 935 ETYSASGSLVQPSTAGFDPLLTQNVIVTERVICPISSVPGNLAGPTQ 981
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 615 bits (1587), Expect = e-176
Identities = 394/1038 (37%), Positives = 567/1038 (54%), Gaps = 109/1038 (10%)
Query: 11 LLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI 70
L++L++ V S ++V EN K + RQKR WI A REGED SK+NPI
Sbjct: 12 LIILMVVMEVNSEFIVEVKEFDIENGTT-KWQTVRRQKREWIKFAAACREGEDNSKRNPI 70
Query: 71 AKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGY 130
AKI SD E KITY+ +G GI PP+G+F N TGE+N+TS++DRE TP FL+
Sbjct: 71 AKIRSDC--ESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCR 128
Query: 131 ALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPN 190
AL++RG ++E+PLELR+KV+DINDN PVF+Q V+ S+EE S A+TLV+K+ ATDADE N
Sbjct: 129 ALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEEN 188
Query: 191 TLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTD 250
LNSKI+Y+IVS EP+ P+F LN+ TGE+ T S LDRE+HS Y L V D +G D
Sbjct: 189 HLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDG-AAD 247
Query: 251 KPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANF 310
+ +I++LDVNDN P +E +EEN ++ E+ R++ D DE G+DNWLA +
Sbjct: 248 GLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQY 307
Query: 311 TFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKP 370
SGN+G +F I+TD QTNEGI+ ++K +DYE+ N+ S+ V N+A FH S+ S+++
Sbjct: 308 LILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQM 367
Query: 371 TPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSS-KGQIIGNFQAFDEDTGLPA-HARY 428
P P++++V +V+EG F S ++ V E + SS ++G + A D DTG PA RY
Sbjct: 368 HPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRY 427
Query: 429 VKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLIN 488
+ D +W+ +DS T EI+ ++ D +S+Y+ NG YT +I+AI +D KT TGT+ I
Sbjct: 428 IIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAI-DDGSGKTATGTICIE 486
Query: 489 VEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIAR 548
V DIND CP + +TIC D+ V ++ + H PF+F V+D+PPG+A+ W +
Sbjct: 487 VPDINDYCPNIFPERRTICIDSPSVLISVNE---HSYGSPFTFCVVDEPPGIADMWDVRS 543
Query: 549 QESTSVLLQQSE-KKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGC-------- 599
+TS +L + G EI L+ D+ +C Q++ L C+C C
Sbjct: 544 TNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGI 603
Query: 600 --REAQHDSY------------VGLGPAAIALMILAFLLLLLVPLLLLMCHC------GK 639
+ D+Y VGLGPA I +M+L LLL+L PLLLL+C C G
Sbjct: 604 YTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGL 663
Query: 640 GAKGFTPIP-GTIEMLHPWNNEGAPPEDKVVPSF-LP-----VDQGGSLVGRNGVGGMA- 691
G + F P+P G ++ W EGA PED++ ++ LP D GGS++GR +
Sbjct: 664 GTR-FAPVPEGGEGVMQSWRIEGAHPEDRLFSAYALPGGGGTADGGGSVLGRCALQATPA 722
Query: 692 --------KEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTE 743
E ++ V+G E++ L++ A GA+GA
Sbjct: 723 LLNQHPPFSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGA---AGASGA----- 774
Query: 744 TTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEE 803
K + G RD A A +N FL +YF++KA +Y +EDE A DCLL+Y E
Sbjct: 775 ARKRSSTMGTLRDYADAD-----INMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEG 829
Query: 804 TESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSM 863
S SIGCCS+I +LD+ ++ L KF+TLAE+CL N EIE
Sbjct: 830 VGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICL------NTEIEP---------- 873
Query: 864 NTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATP 923
SH C + S + G ++ V +S +E QE E + S
Sbjct: 874 -FPSHQAC---IPISTDLPLLGPNYFVNESSGLTPSEVEFQE---EMAAS---------- 916
Query: 924 LPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQSLIVTERVYAP-----ASTLVDQP 978
+P+ ++I TET + PTT+I P +++VTE V AP + V
Sbjct: 917 --EPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAE 974
Query: 979 YANEGTVVVTERVIQPHG 996
A+ V+ ERV+ G
Sbjct: 975 LADYNNVIYAERVLASPG 992
Score = 33.9 bits (76), Expect = 0.89
Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 35/122 (28%)
Query: 1029 VQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTE----NSMTARNTTVSGAGVP-- 1082
VQPT + + + NV VTE V+AP +Q + +P E N++ ++ GVP
Sbjct: 937 VQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDM 996
Query: 1083 ----------GPL------------------PDFGLEESGHSNSTITTSSTRVTKHSTVQ 1114
GP+ PD + ++ S S + TS RVT++S +
Sbjct: 997 SNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPM-TSRHRVTRYSNIH 1055
Query: 1115 HS 1116
++
Sbjct: 1056 YT 1057
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 610 bits (1572), Expect = e-174
Identities = 388/1023 (37%), Positives = 558/1023 (54%), Gaps = 98/1023 (9%)
Query: 11 LLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI 70
L++L++ V S ++V EN K + RQKR WI A REGED SK+NPI
Sbjct: 12 LIILMVVMEVNSEFIVEVKEFDIENGTT-KWQTVRRQKREWIKFAAACREGEDNSKRNPI 70
Query: 71 AKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGY 130
AKI SD E KITY+ +G GI PP+G+F N TGE+N+TS++DRE TP FL+
Sbjct: 71 AKIRSDC--ESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCR 128
Query: 131 ALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPN 190
AL++RG ++E+PLELR+KV+DINDN PVF+Q V+ S+EE S A+TLV+K+ ATDADE N
Sbjct: 129 ALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEEN 188
Query: 191 TLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTD 250
LNSKI+Y+IVS EP+ P+F LN+ TGE+ T S LDRE+HS Y L V D +G D
Sbjct: 189 HLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDG-AAD 247
Query: 251 KPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANF 310
+ +I++LDVNDN P +E +EEN ++ E+ R++ D DE G+DNWLA +
Sbjct: 248 GLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQY 307
Query: 311 TFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKP 370
SGN+G +F I+TD QTNEGI+ ++K +DYE+ N+ S+ V N+A FH S+ S+++
Sbjct: 308 LILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQM 367
Query: 371 TPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSS-KGQIIGNFQAFDEDTGLPA-HARY 428
P P++++V +V+EG F S ++ V E + SS ++G + A D DTG PA RY
Sbjct: 368 HPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRY 427
Query: 429 VKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLIN 488
+ D +W+ +DS T EI+ ++ D +S+Y+ NG YT +I+AI +D KT TGT+ I
Sbjct: 428 IIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAI-DDGSGKTATGTICIE 486
Query: 489 VEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIAR 548
V DIND CP + +TIC D+ V ++ + H PF+F V+D+PPG+A+ W +
Sbjct: 487 VPDINDYCPNIFPERRTICIDSPSVLISVNE---HSYGSPFTFCVVDEPPGIADMWDVRS 543
Query: 549 QESTSVLLQQSE-KKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGC-------- 599
+TS +L + G EI L+ D+ +C Q++ L C+C C
Sbjct: 544 TNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGI 603
Query: 600 --REAQHDSY------------VGLGPAAIALMILAFLLLLLVPLLLLMCHC------GK 639
+ D+Y VGLGPA I +M+L LLL+L PLLLL+C C G
Sbjct: 604 YTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGL 663
Query: 640 GAKGFTPIP-GTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKG 698
G + F P+P G ++ W EGA PED+ V + + R + E
Sbjct: 664 GTR-FAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMD----SSEIYTNT 718
Query: 699 SSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMA 758
++ V+G E++ L++ A GA+GA K + G RD A
Sbjct: 719 YAAGGTVEGGVSGVELNTGMGTAVGLMAAGA---AGASGA-----ARKRSSTMGTLRDYA 770
Query: 759 GAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIE 818
A +N FL +YF++KA +Y +EDE A DCLL+Y E S SIGCCS+I
Sbjct: 771 DAD-----INMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIV 825
Query: 819 GELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNS 878
+LD+ ++ L KF+TLAE+CL N EIE SH C + S
Sbjct: 826 DDLDESCMETLDPKFRTLAEICL------NTEIEP-----------FPSHQAC---IPIS 865
Query: 879 ENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATET 938
+ G ++ V +S +E QE E + S +P+ ++I TET
Sbjct: 866 TDLPLLGPNYFVNESSGLTPSEVEFQE---EMAAS------------EPVVHGDIIVTET 910
Query: 939 SYVTGSTMPPTTVILGPSQPQSLIVTERVYAP-----ASTLVDQPYANEGTVVVTERVIQ 993
+ PTT+I P +++VTE V AP + V A+ V+ ERV+
Sbjct: 911 YGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLA 970
Query: 994 PHG 996
G
Sbjct: 971 SPG 973
Score = 33.9 bits (76), Expect = 0.89
Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 35/122 (28%)
Query: 1029 VQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTE----NSMTARNTTVSGAGVP-- 1082
VQPT + + + NV VTE V+AP +Q + +P E N++ ++ GVP
Sbjct: 918 VQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDM 977
Query: 1083 ----------GPL------------------PDFGLEESGHSNSTITTSSTRVTKHSTVQ 1114
GP+ PD + ++ S S + TS RVT++S +
Sbjct: 978 SNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPM-TSRHRVTRYSNIH 1036
Query: 1115 HS 1116
++
Sbjct: 1037 YT 1038
>gi|119703744 desmoglein 1 preproprotein [Homo sapiens]
Length = 1049
Score = 548 bits (1412), Expect = e-155
Identities = 409/1165 (35%), Positives = 579/1165 (49%), Gaps = 187/1165 (16%)
Query: 11 LLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI 70
L + L+ V S +QV +N + H + RQKR WI A REGED SK+NPI
Sbjct: 12 LFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHS-IRRQKREWIKFAAACREGEDNSKRNPI 70
Query: 71 AKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGY 130
AKIHSD A + ++TY+ +G GI +PP+GIFV N+ TGE+N+TSI+DRE TPFF++
Sbjct: 71 AKIHSDCAANQ--QVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCR 128
Query: 131 ALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPN 190
AL++ G ++E+PLELR++VLDINDN PVF+ F G +EE S A+TLVM +NATDADEPN
Sbjct: 129 ALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPN 188
Query: 191 TLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTD 250
LNSKI+++I+ EP+ P+F +N++TGEI T + LDRE++ Y L V D +G D
Sbjct: 189 NLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGG-AD 247
Query: 251 KPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANF 310
+ + I+ILDVNDNIP +E ++EN +N + I+V D DE S NW+A
Sbjct: 248 GMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVI 307
Query: 311 TFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKP 370
F SGNEG +F IE + +TN GI+ ++K +DYE M++L S+ V NKA FH SI S+YK
Sbjct: 308 FFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKL 367
Query: 371 TPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPA-HARYV 429
I V V NV EG F+ + V+ +M + K +G+F A D DTG P+ RYV
Sbjct: 368 KASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDK---VGDFVATDLDTGRPSTTVRYV 424
Query: 430 KLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINV 489
+ + ++VDS T ++ L E + G Y I++I +D ++T TGT+ IN+
Sbjct: 425 MGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSI-DDNLQRTCTGTININI 483
Query: 490 EDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQ 549
+ ++ T EP I N+G RQ
Sbjct: 484 QSFGNDDRTNTEPNTKIT----------------TNTG--------------------RQ 507
Query: 550 ESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVG 609
ESTS D S QV + G+G ++ D+ V
Sbjct: 508 ESTSSTNY----------------DTSTTSTDSSQVYSSE-----PGNGAKDLLSDN-VH 545
Query: 610 LGPAAIALMILAFLLLLLVPLLLLMCHCG---KGAKGFTPIPGTIE-MLHPWNNEGAPPE 665
GPA I L+I+ FL+L LVP L++ C CG + A GF P+P + +H W EG PE
Sbjct: 546 FGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPE 605
Query: 666 DK----VVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEH 721
+ V+P +P D + + G E G EM ++ G
Sbjct: 606 PRDITTVIPQ-IPPDNANIIECIDNSGVYTNE------------YGGREMQDLGG----- 647
Query: 722 RSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAA 781
R T F G + +G R + + LN F+ +YF KA
Sbjct: 648 ----GERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAY 703
Query: 782 SYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCL 841
+Y +EDE + DCLL+Y E S S+GCCSFI +LDD FLD LG KFK LA++ L
Sbjct: 704 AYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISL 763
Query: 842 GQKI--DINKE----------IEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFP 889
G++ D++ + Q +P + H T V SE+TY SG
Sbjct: 764 GKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPH--FGTTTVISESTYPSGPGVL 821
Query: 890 VPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPT 949
PK P+ DP+ NV TE SY T T+ P+
Sbjct: 822 HPK------------------------------PILDPLGYGNVTVTE-SYTTSDTLKPS 850
Query: 950 TVILGPSQPQSLIVTERVYAPAS-----TLVDQPYANEGT-VVVTERVIQPHGGGSNPLE 1003
+ +++VTERV P S +++ P +G+ V+VTERVI P L
Sbjct: 851 VHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLT 910
Query: 1004 GTQHLQDVPYVMVRERESFLAPSSGVQPTLAM-PNIAVGQNVTVTERVLAPAST------ 1056
H ++ V+V ER + P+SG+ +L+M P +A NV VTERV++ A
Sbjct: 911 -IHHPRESSNVVVTER--VIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGT 967
Query: 1057 ------LQSSYQIPTENSMTARNTTVSGAGVPGPLPDFGLEESG--------------HS 1096
+ SS + T SM A + +SGAG+ G GL G H
Sbjct: 968 TGISGGIGSSGLVGT--SMGAGSGALSGAGISG--GGIGLSSLGGTASIGHMRSSSDHHF 1023
Query: 1097 NSTI-----TTSSTRVTKHSTVQHS 1116
N TI +T+ +R+TK+STVQ+S
Sbjct: 1024 NQTIGSASPSTARSRITKYSTVQYS 1048
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 337 bits (865), Expect = 3e-92
Identities = 236/798 (29%), Positives = 379/798 (47%), Gaps = 35/798 (4%)
Query: 44 LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFV 103
L R KR W P +++E + ++ SD A+ + Y +G+G+ + P +F
Sbjct: 130 LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQN--YTVFYSISGRGVDKEPLNLFY 187
Query: 104 FNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDV 163
+DTG L T +DREE F L YA A G + + PL L I+V D NDN PVFT+ +
Sbjct: 188 IERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAI 247
Query: 164 FVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTT 223
+ V E S T V + ATD DEP+T+++++ Y I+ P P +F ++ TG I T
Sbjct: 248 YNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTV 307
Query: 224 SVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEE 283
S LDRE Y+L ++ +D +G+ + + I + D NDN P E VEE
Sbjct: 308 SHYLDREVVDKYSLIMKVQDMDGQFFGL-IGTSTCIITVTDSNDNAPTFRQNAYEAFVEE 366
Query: 284 NQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYE 343
N NVE+ RI + D D I + NW NFT GNE G+F I TD +TNEG+++++K ++YE
Sbjct: 367 NAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYE 426
Query: 344 EMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDR 403
E + ++ + V N+A F + I + V V+++ EG + + + E++
Sbjct: 427 ENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAV 486
Query: 404 SSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNG 463
SK I ++A+D + RY KL D WI++D ++ I +K+ D E +N
Sbjct: 487 GSK---INGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNE 543
Query: 464 TYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH-DAEYVNVTAEDLDG 522
Y + ++AI +D ++ TGT+ +N+ED+NDN P +++ IC Y ++ A D D
Sbjct: 544 LYNITVLAIDKD--DRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDE 601
Query: 523 HPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPE 582
+ PF FS+ + P ++ W + + T+ L +K G E I+
Sbjct: 602 PVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSY-QKNAGFQEYTIPITVKDRAGQAA 660
Query: 583 KQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAK 642
++L + +CEC H + CR + V LG AI ++L LL V LL L+C K
Sbjct: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSV-LLTLVCGVFGATK 719
Query: 643 GFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSA 702
G + +N AP +D+V + + Q + + G M G +
Sbjct: 720 GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETI 779
Query: 703 SIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQA 762
++KG ++ E H +L S R G + + + S
Sbjct: 780 EMMKGGNQTLESCRGAGHHHTLDSCR--------GGHTEVDNCRYTYSEWHS-------- 823
Query: 763 AAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELD 822
F + +K + ++ ++D +L Y+ E S S+GCCS + E
Sbjct: 824 --------FTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDG 875
Query: 823 DRFLDDLGLKFKTLAEVC 840
FL++L KF TLAE C
Sbjct: 876 LDFLNNLEPKFITLAEAC 893
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 336 bits (862), Expect = 6e-92
Identities = 204/598 (34%), Positives = 304/598 (50%), Gaps = 12/598 (2%)
Query: 43 HLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIF 102
HL RQKR W+ P+ L E + +I SD ++ L + Y TG G +PP GIF
Sbjct: 153 HLQRQKRDWVIPPINLPENSRGPFPQELVRIRSD--RDKNLSLRYSVTGPGADQPPTGIF 210
Query: 103 VFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQD 162
+ N +G+L+VT LDRE+ F L +A+D GN VE P+++ I V+D+NDN P F
Sbjct: 211 IINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQ 270
Query: 163 VFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPP--VFYLNKDTGEI 220
V+ G+V E S T VM + A DAD+PN LN + YRIVS P+ P +F +N +TG+I
Sbjct: 271 VWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDI 330
Query: 221 YTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGM 280
T + LDRE+ YTL ++A D G T A I + DVNDN P G
Sbjct: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
Query: 281 VEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEV 340
V EN+V++ V + V D D+ + W A + + G+ G F I+TD +N+G+VT++K +
Sbjct: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
Query: 341 DYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSES 400
D+E + +V N+ K I+ + T + V V +V E +F + I E
Sbjct: 451 DFETNRMFVLTVAAENQVPLAKGIQHPPQST-ATVSVTVIDVNENPYFAPNPKIIRQEEG 509
Query: 401 MDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYV 460
+ G ++ F A D D + + RY KL D NW+ +D V +I + D ES V
Sbjct: 510 L---HAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
Query: 461 QNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH--DAEYVNVTAE 518
+N Y +A P + TGT+ I + DINDN P ++ C D +N+TA
Sbjct: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPDPNSINITAL 626
Query: 519 DLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKL--GRSEIQFLISDNQ 576
D D PN+GPF+F + P + W I R L K L G E+ +I+D+
Sbjct: 627 DYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSG 686
Query: 577 GFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLM 634
+L + VC+C C + GLG AI ++L ++LL++ L+ ++
Sbjct: 687 NPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVV 744
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 327 bits (839), Expect = 3e-89
Identities = 196/605 (32%), Positives = 306/605 (50%), Gaps = 15/605 (2%)
Query: 39 PKHPH---LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGIT 95
P+H + L R+KR W+ P+ + E + +I SD ++ + I Y TG G
Sbjct: 156 PQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSD--KDNDIPIRYSITGVGAD 213
Query: 96 EPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDN 155
+PP +F + +G + VT +DREE + L +A+D GN VE P++L I V+D+NDN
Sbjct: 214 QPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDN 273
Query: 156 EPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPP--VFYL 213
P F V+ GSV+E S T VM + A DAD+ T N + YRIV+ P P +F +
Sbjct: 274 RPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTI 333
Query: 214 NKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVE 273
N +TG+I T + LDRE+ YT+ V+A D G + A I + DVNDN P
Sbjct: 334 NSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFT 393
Query: 274 NKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGI 333
G V EN+V V + V D D+ S NW A + SG+ G+F + TD TNEG+
Sbjct: 394 ASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGM 453
Query: 334 VTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVI 393
VT++K VDYE + +V+V+N+A I+ ++ T + + + ++ E +F S+
Sbjct: 454 VTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQST-AGVTISIMDINEAPYFPSNHK 512
Query: 394 SIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLP 453
I + E + G ++ F A D D + RY KL D +W+ +++ +I A +
Sbjct: 513 LIRLEEGV---PPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVL 569
Query: 454 DFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH--DAE 511
D ES Y +N Y +A P + TGT+ I + DINDN P L+ IC +
Sbjct: 570 DRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLN 629
Query: 512 YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIAR--QESTSVLLQQSEKKLGRSEIQ 569
+N+TA D D PN GP+ F + P + + W I R + + L+ + G ++
Sbjct: 630 AINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVP 689
Query: 570 FLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVP 629
+++D+ ++ + VC C C + GLG AI +++ L+LL +
Sbjct: 690 IIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMV 749
Query: 630 LLLLM 634
LL +M
Sbjct: 750 LLFVM 754
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 326 bits (835), Expect = 9e-89
Identities = 247/815 (30%), Positives = 387/815 (47%), Gaps = 54/815 (6%)
Query: 40 KHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPF 99
K L R KR W P ++ E + ++ SD A+ I Y G G+ + P
Sbjct: 126 KEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQN--YTIYYSIRGPGVDQEPR 183
Query: 100 GIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVF 159
+F +DTG L T +DRE+ F + +A G E PL L IK+ D NDN P+F
Sbjct: 184 NLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIF 243
Query: 160 TQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGE 219
T++ + ++ E T V ++ ATD DEP+T+++++ Y I+ P P +F ++ TG
Sbjct: 244 TEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGV 303
Query: 220 IYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEG 279
I TTS LDRE Y L ++ +D +G+ + I I DVND++P
Sbjct: 304 ITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCI-INIDDVNDHLPTFTRTSYVT 362
Query: 280 MVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKE 339
VEEN V+VE+ R+ V D D + + NW AN+T GNE G F I TDA+TNEG++ ++K
Sbjct: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
Query: 340 VDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSE 399
++YEE + + + V N+A F + + + + V V++ EG + ++ + E
Sbjct: 423 LNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKE 482
Query: 400 SMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRY 459
+ + G ++A+D +T + RY KL D W+++D T IK+ + D E+
Sbjct: 483 N---AEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539
Query: 460 VQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDA-EYVNVTAE 518
++NG Y + ++A D +T TGT+ I ++D+NDN P + + IC + A
Sbjct: 540 IKNGIYNITVLA--SDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAV 597
Query: 519 DLDGHPNSGPFSFSVIDKPPGMAEKWKI-ARQESTSVLLQQSEKKLGRSEIQFLISDNQG 577
D D + PF FS+ + W++ A ++ + L Q++ G + + D G
Sbjct: 598 DPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLG 657
Query: 578 FSCPEKQVLTLTVCECLHGSGCREAQHDSYVG-----LGPAAIALMILAFLLLLLVPLLL 632
S L +T+C+C+ + C + D +G LG AI ++L LL + L
Sbjct: 658 MSSVTS--LDVTLCDCITENDCTH-RVDPRIGGGGVQLGKWAILAILLGIALLFCI-LFT 713
Query: 633 LMCHCGKGAKGFTPIPGTIEMLH-PWNNEGAPPEDKVVPS--FLPVDQGGSLVGRNG-VG 688
L+C +K IP + + +N AP +DKV + F G S G G VG
Sbjct: 714 LVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVG 773
Query: 689 GMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTA 748
K G + +VKG H+ SE H +L S R G T T
Sbjct: 774 SGIKNG---GQETIEMVKGGHQTSESCRGAGHHHTLDSCRG----GHTEVDNCRYTYSEW 826
Query: 749 RATGASRDMAGAQAAAVALNEE-FLRNYFTDKAASYTEEDENHT-AKDCLLVYSQEETES 806
+ R L E+ +L N +DENH A+D +L Y+ E S
Sbjct: 827 HSFTQPR-----------LGEKVYLCN-----------QDENHKHAQDYVLTYNYEGRGS 864
Query: 807 LNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCL 841
+ S+GCCS + E FLD+L KF+TLAE C+
Sbjct: 865 VAGSVGCCSERQEEDGLEFLDNLEPKFRTLAEACM 899
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 323 bits (829), Expect = 4e-88
Identities = 257/833 (30%), Positives = 393/833 (47%), Gaps = 64/833 (7%)
Query: 26 LQVLSTRNENKLLPKHPH-----LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEE 80
++V+ + ENK PK H L R KR W P +L E + +I SD A+
Sbjct: 107 IKVVLSARENKS-PKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQN 165
Query: 81 RGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVE 140
I Y +G G+ + PF +F KDTG++ T +DRE+ F L GYA A G E
Sbjct: 166 --YTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPE 223
Query: 141 KPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRI 200
PL L IK+ D NDN P F V + +V E + T V K+ ATD DEP+TL++++ Y+I
Sbjct: 224 YPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKI 283
Query: 201 VSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQI 260
+ P +P F ++ DTG I TT+ LDRE+ +Y L +E RD G+ + I
Sbjct: 284 LQQIPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGL-FNTGTITI 342
Query: 261 RILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGY 320
+ D NDN P VEEN+++VE+ R+KV D D + + A + GNE G
Sbjct: 343 SLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGN 402
Query: 321 FHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPT--PIPIKVK 378
F I TD TNEG++ ++K ++YE + + V V N+A F K+ S+ PT + VK
Sbjct: 403 FIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQ-TPTMCTTTVTVK 461
Query: 379 VKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWI 438
+ + EG V V +S D GQ + ++A D + RY KL D DNW
Sbjct: 462 IIDSDEGPECHPPV---KVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWF 518
Query: 439 SVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPT 498
++ T +++ K+ D ES++V+N Y + +VA+ D ++ TGT++++++D ND+ P
Sbjct: 519 EINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV--DAVGRSCTGTLVVHLDDYNDHAPQ 576
Query: 499 LIEPVQTICHDAE-YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQE-STSVLL 556
+ + V TIC + E + + D DG N PF F + + ++ W I ++ T++L
Sbjct: 577 IDKEV-TICQNNEDFAVLKPVDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILR 632
Query: 557 QQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDS-----YVGLG 611
Q+ + I D G +LT+ VC+C S CR + V LG
Sbjct: 633 QRQNLDYNYYSVPIQIKDRHGLVA--THMLTVRVCDCSTPSECRMKDKSTRDVRPNVILG 690
Query: 612 PAAIALMILAFLLLLLVPLLLLMCHC---GKGAKGFTPIPGTIEMLHPWNNEGAPPEDKV 668
AI M+L +LLL + L C C + K P + L N EG E
Sbjct: 691 RWAILAMVLGSVLLLCI---LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTE 747
Query: 669 VPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGR 728
LP+ VG + + +K S +VKG + + G H++L S +
Sbjct: 748 ANIRLPMQTSNICDTSMSVGTVGGQG-IKTQQSFEMVKGGYTLDSNKG--GGHQTLESVK 804
Query: 729 ATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDE 788
G TG T+ + F + +K +++E
Sbjct: 805 GVG-QGDTGRYAYTDW------------------------QSFTQPRLGEKVYLCGQDEE 839
Query: 789 NHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCL 841
+ +D + Y+ E SL S+GCCS + E FLD L KF+TLA+ C+
Sbjct: 840 HKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCI 892
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 320 bits (821), Expect = 4e-87
Identities = 211/686 (30%), Positives = 338/686 (49%), Gaps = 11/686 (1%)
Query: 44 LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFV 103
L R KR W P +++E + ++ SD A+ + Y +G+G+ + P +F
Sbjct: 130 LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQN--YTVFYSISGRGVDKEPLNLFY 187
Query: 104 FNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDV 163
+DTG L T +DREE F L YA A G + + PL L I+V D NDN PVFT+ +
Sbjct: 188 IERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAI 247
Query: 164 FVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTT 223
+ V E S T V + ATD DEP+T+++++ Y I+ P P +F ++ TG I T
Sbjct: 248 YNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTV 307
Query: 224 SVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEE 283
S LDRE Y+L ++ +D +G+ + + I + D NDN P E VEE
Sbjct: 308 SHYLDREVVDKYSLIMKVQDMDGQFFGL-IGTSTCIITVTDSNDNAPTFRQNAYEAFVEE 366
Query: 284 NQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYE 343
N NVE+ RI + D D I + NW NFT GNE G+F I TD +TNEG+++++K ++YE
Sbjct: 367 NAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYE 426
Query: 344 EMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDR 403
E + ++ + V N+A F + I + V V+++ EG + + + E++
Sbjct: 427 ENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAV 486
Query: 404 SSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNG 463
SK I ++A+D + RY KL D WI++D ++ I +K+ D E +N
Sbjct: 487 GSK---INGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNE 543
Query: 464 TYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH-DAEYVNVTAEDLDG 522
Y + ++AI +D ++ TGT+ +N+ED+NDN P +++ IC Y ++ A D D
Sbjct: 544 LYNITVLAIDKD--DRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDE 601
Query: 523 HPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPE 582
+ PF FS+ + P ++ W + + T+ L +K G E I+
Sbjct: 602 PVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSY-QKNAGFQEYTIPITVKDRAGQAA 660
Query: 583 KQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAK 642
++L + +CEC H + CR + V LG AI ++L LL V LL L+C K
Sbjct: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSV-LLTLVCGVFGATK 719
Query: 643 GFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSA 702
G + +N AP +D+V + + Q + + G M G +
Sbjct: 720 GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETI 779
Query: 703 SIVKGQHEMSEMDGRWEEHRSLLSGR 728
++KG ++ E H +L S R
Sbjct: 780 EMMKGGNQTLESCRGAGHHHTLDSCR 805
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 300 bits (768), Expect = 5e-81
Identities = 212/700 (30%), Positives = 339/700 (48%), Gaps = 26/700 (3%)
Query: 40 KHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPF 99
K L R KR W P ++ E + ++ SD A+ I Y G G+ + P
Sbjct: 126 KEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQN--YTIYYSIRGPGVDQEPR 183
Query: 100 GIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVF 159
+F +DTG L T +DRE+ F + +A G E PL L IK+ D NDN P+F
Sbjct: 184 NLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIF 243
Query: 160 TQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGE 219
T++ + ++ E T V ++ ATD DEP+T+++++ Y I+ P P +F ++ TG
Sbjct: 244 TEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGV 303
Query: 220 IYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEG 279
I TTS LDRE Y L ++ +D +G+ + I I DVND++P
Sbjct: 304 ITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCI-INIDDVNDHLPTFTRTSYVT 362
Query: 280 MVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKE 339
VEEN V+VE+ R+ V D D + + NW AN+T GNE G F I TDA+TNEG++ ++K
Sbjct: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
Query: 340 VDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSE 399
++YEE + + + V N+A F + + + + V V++ EG + ++ + E
Sbjct: 423 LNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKE 482
Query: 400 SMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRY 459
+ + G ++A+D +T + RY KL D W+++D T IK+ + D E+
Sbjct: 483 N---AEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539
Query: 460 VQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDA-EYVNVTAE 518
++NG Y + ++A D +T TGT+ I ++D+NDN P + + IC + A
Sbjct: 540 IKNGIYNITVLA--SDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAV 597
Query: 519 DLDGHPNSGPFSFSVIDKPPGMAEKWKI-ARQESTSVLLQQSEKKLGRSEIQFLISDNQG 577
D D + PF FS+ + W++ A ++ + L Q++ G + + D G
Sbjct: 598 DPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLG 657
Query: 578 FSCPEKQVLTLTVCECLHGSGCREAQHDSYVG-----LGPAAIALMILAFLLLLLVPLLL 632
S L +T+C+C+ + C + D +G LG AI ++L LL + L
Sbjct: 658 MSSVTS--LDVTLCDCITENDCTH-RVDPRIGGGGVQLGKWAILAILLGIALLFCI-LFT 713
Query: 633 LMCHCGKGAKGFTPIPGTIEMLH-PWNNEGAPPEDKVVPS--FLPVDQGGSLVGRNG-VG 688
L+C +K IP + + +N AP +DKV + F G S G G VG
Sbjct: 714 LVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVG 773
Query: 689 GMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGR 728
K G + +VKG H+ SE H +L S R
Sbjct: 774 SGIKNG---GQETIEMVKGGHQTSESCRGAGHHHTLDSCR 810
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 298 bits (764), Expect = 1e-80
Identities = 229/726 (31%), Positives = 348/726 (47%), Gaps = 37/726 (5%)
Query: 26 LQVLSTRNENKLLPKHPH-----LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEE 80
++V+ + ENK PK H L R KR W P +L E + +I SD A+
Sbjct: 107 IKVVLSARENKS-PKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQN 165
Query: 81 RGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVE 140
I Y +G G+ + PF +F KDTG++ T +DRE+ F L GYA A G E
Sbjct: 166 --YTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPE 223
Query: 141 KPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRI 200
PL L IK+ D NDN P F V + +V E + T V K+ ATD DEP+TL++++ Y+I
Sbjct: 224 YPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKI 283
Query: 201 VSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQI 260
+ P +P F ++ DTG I TT+ LDRE+ +Y L +E RD G+ + I
Sbjct: 284 LQQIPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGL-FNTGTITI 342
Query: 261 RILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGY 320
+ D NDN P VEEN+++VE+ R+KV D D + + A + GNE G
Sbjct: 343 SLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGN 402
Query: 321 FHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPT--PIPIKVK 378
F I TD TNEG++ ++K ++YE + + V V N+A F K+ S+ PT + VK
Sbjct: 403 FIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQ-TPTMCTTTVTVK 461
Query: 379 VKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWI 438
+ + EG V V +S D GQ + ++A D + RY KL D DNW
Sbjct: 462 IIDSDEGPECHPPV---KVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWF 518
Query: 439 SVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPT 498
++ T +++ K+ D ES++V+N Y + +VA+ D ++ TGT++++++D ND+ P
Sbjct: 519 EINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV--DAVGRSCTGTLVVHLDDYNDHAPQ 576
Query: 499 LIEPVQTICHDAE-YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQE-STSVLL 556
+ + V TIC + E + + D DG N PF F + + ++ W I ++ T++L
Sbjct: 577 IDKEV-TICQNNEDFAVLKPVDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILR 632
Query: 557 QQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDS-----YVGLG 611
Q+ + I D G +LT+ VC+C S CR + V LG
Sbjct: 633 QRQNLDYNYYSVPIQIKDRHGLVA--THMLTVRVCDCSTPSECRMKDKSTRDVRPNVILG 690
Query: 612 PAAIALMILAFLLLLLVPLLLLMCHC---GKGAKGFTPIPGTIEMLHPWNNEGAPPEDKV 668
AI M+L +LLL + L C C + K P + L N EG E
Sbjct: 691 RWAILAMVLGSVLLLCI---LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTE 747
Query: 669 VPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGR 728
LP+ VG + + +K S +VKG + + G + + G
Sbjct: 748 ANIRLPMQTSNICDTSMSVGTVGGQG-IKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGV 806
Query: 729 ATQFTG 734
TG
Sbjct: 807 GQGDTG 812
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 294 bits (752), Expect = 4e-79
Identities = 217/661 (32%), Positives = 329/661 (49%), Gaps = 43/661 (6%)
Query: 22 SGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEER 81
SG+ ++L+ N + P L RQKR W+ P++ E E + +I S+ +E
Sbjct: 133 SGIQAELLTFPNSS------PGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEG 186
Query: 82 GLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEK 141
K+ Y TG+G PP G+F+ ++TG L VT LDRE + L +A+ + GN VE
Sbjct: 187 --KVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVED 244
Query: 142 PLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEP-NTLNSKISYRI 200
P+E+ I V D NDN+P FTQ+VF GSV E + T VM++ ATDAD+ NT N+ I+Y I
Sbjct: 245 PMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI 304
Query: 201 VSLEPAYPP--VFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQV 258
+S +P P +F +N++TG I + LDRE +YTL V+A D GE A
Sbjct: 305 LSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLS---TTATA 361
Query: 259 QIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEG 318
I + D NDN P+ +G V EN+ NV +T +KV DAD + W A +T + ++G
Sbjct: 362 VITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILN-DDG 420
Query: 319 GYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVK 378
G F + T+ N+GI+ K +D+E + V V N F S+ + + + V
Sbjct: 421 GQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTT----STATVTVD 476
Query: 379 VKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWI 438
V +V E F + VSE GQ I ++ A + DT + Y D NW+
Sbjct: 477 VLDVNEAPIFVPPEKRVEVSEDF---GVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
Query: 439 SVDSVTSEIKL-AKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCP 497
++ T I A+L + +V+N TYT I+A P T TGT+L+ + D+NDN P
Sbjct: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
Query: 498 TLIEPVQTICH---DAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTS- 553
C + +N+ DL PN+ PF+ + G + W I + T
Sbjct: 594 IPEPRTIFFCERNPKPQVINIIDADLP--PNTSPFTAELTH---GASANWTIQYNDPTQE 648
Query: 554 --VLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTL--TVCECLHGSG-CREAQHDSYV 608
+L + ++G +I + DNQ + QV TL +VC+C +G CR+AQ
Sbjct: 649 SIILKPKMALEVGDYKINLKLMDNQN----KDQVTTLEVSVCDCEGAAGVCRKAQPVEAG 704
Query: 609 GLGPAAIALM--ILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPED 666
PA + ++ ILA L+L+L+ LL L P T + ++ ++ EG ED
Sbjct: 705 LQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED 764
Query: 667 K 667
+
Sbjct: 765 Q 765
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 278 bits (711), Expect = 2e-74
Identities = 203/673 (30%), Positives = 331/673 (49%), Gaps = 27/673 (4%)
Query: 10 ALLLLLICFNVGSGLHLQVLSTRNENKLLP--KHPHLVRQKRAWITAPVALREGEDLSKK 67
A LL+L L L V R L P + P L R +RAW+ P+++ E
Sbjct: 4 AFLLVLGLLAQSLCLSLGVPGWRRPTTLYPWRRAPALSRVRRAWVIPPISVSENHK-RLP 62
Query: 68 NPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLL 127
P+ +I SD +++ + Y G G+ E P G+F +K TG++ + ++LDRE+T F L
Sbjct: 63 YPLVQIKSD--KQQLGSVIYSIQGPGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRL 120
Query: 128 TGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDAD 187
+ALD G+ +E P +L I V+D NDN P F Q+ F G V E + T V + ATDAD
Sbjct: 121 RAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEATDAD 180
Query: 188 EPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGE 247
+P T N+ + + I L+ P +F +++ TGEI T V LDRE + Y LT++ D +G
Sbjct: 181 DPETDNAALRFSI--LQQGSPELFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSG- 237
Query: 248 VTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWL 307
D A I + D+NDN P E V+V R++V D D GS NW+
Sbjct: 238 --DGLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWV 295
Query: 308 ANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSK 367
A FT G+ G F I TD +TNEG+++++K +DYE ++ + V V N+A ++ +
Sbjct: 296 ARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEHYELKVSVQNEAPL-QAAALR 354
Query: 368 YKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHAR 427
+ ++V V++ E F+ + + ++E + G ++ F A D DT
Sbjct: 355 AERGQAKVRVHVQDTNEPPVFQENPLRTSLAEG---APPGTLVATFSARDPDTEQLQRLS 411
Query: 428 YVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLI 487
Y K D ++W+ VD+ T I+ + S +++ G Y ++A + +T TGT+ I
Sbjct: 412 YSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRAIVLAQDDASQPRTATGTLSI 471
Query: 488 NVEDINDNCPTLIEPVQ-TIC---HDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEK 543
+ ++ND+ P L P ++C H + + A D D P+ PF F + + P +
Sbjct: 472 EILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDEDLPPHGAPFHFQLSPRLPELGRN 531
Query: 544 WKIAR-QESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGC--- 599
W +++ S + L + + G + L+ D+ +Q L +TVC C C
Sbjct: 532 WSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPG 591
Query: 600 REAQHDSYVGLGPAAIALMIL-AFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHP-- 656
A GL A+ +++ A LLL+LV L+ L K ++G + G + L
Sbjct: 592 AAALLAGGTGLSLGALVIVLASALLLLVLVLLVALRARFWKQSRGKGLLHGPQDDLRDNV 651
Query: 657 --WNNEGAPPEDK 667
++ +G ED+
Sbjct: 652 LNYDEQGGGEEDQ 664
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 255 bits (651), Expect = 2e-67
Identities = 201/613 (32%), Positives = 301/613 (49%), Gaps = 35/613 (5%)
Query: 29 LSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLA--EERGLKIT 86
L RN K+ P L R KR W+ AP+++ E + K P + + L ++R KI
Sbjct: 87 LKERNPLKIFPSKRILRRHKRDWVVAPISVPE----NGKGPFPQRLNQLKSNKDRDTKIF 142
Query: 87 YKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELR 146
Y TG G PP G+F K+TG L + LDREE + L G+A+ G +VE P+ +
Sbjct: 143 YSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNIS 202
Query: 147 IKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEP-NTLNSKISYRIVSLEP 205
I V D ND++P FTQD F GSV E T VM++ ATD D+ T N ++Y I S EP
Sbjct: 203 IIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEP 262
Query: 206 AYPP--VFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRIL 263
P +F +++ TG I S LDRE+ YTLT++A D +G D A + IL
Sbjct: 263 KDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDG---DGSTTTAVAVVEIL 319
Query: 264 DVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHI 323
D NDN P+ + + E V EN V EV R+ V D D S W A + G++G +F I
Sbjct: 320 DANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTI 379
Query: 324 ETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVK 383
T ++N+GI+T K +D+E V V N+A F K + I V V++V
Sbjct: 380 TTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPF----VLKLPTSTATIVVHVEDVN 435
Query: 384 EGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSV 443
E F + V E + G+ + + A D D Y L D W+++D
Sbjct: 436 EAPVFVPPSKVVEVQEGI---PTGEPVCVYTAEDPDKE-NQKISYRILRDPAGWLAMDPD 491
Query: 444 TSEIKLAKLPDFE-SRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEP 502
+ ++ D E ++V+N Y V ++A+ P T TGT+L+ + D+ND+ P + EP
Sbjct: 492 SGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEP 550
Query: 503 VQ-TICHDA---EYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQ 558
Q TIC+ + + +N+T +DL P++ PF + D W E ++
Sbjct: 551 RQITICNQSPVRQVLNITDKDLS--PHTSPFQAQLTDDSD---IYWTAEVNEEGDTVVLS 605
Query: 559 SEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECL-HGSGCREAQHDSYV--GLGPAAI 615
+K L + +S + + + V+ TVC+C H C ++ LG A +
Sbjct: 606 LKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVLG-AVL 664
Query: 616 ALMILAFLLLLLV 628
AL+ L +LLLLV
Sbjct: 665 ALLFLLLVLLLLV 677
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 253 bits (646), Expect = 7e-67
Identities = 185/598 (30%), Positives = 286/598 (47%), Gaps = 29/598 (4%)
Query: 46 RQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFN 105
RQKR+ + +P+ + E + + K+ ER ++ TGKG+ + P GIF N
Sbjct: 135 RQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERS---KFRLTGKGVDQEPKGIFRIN 191
Query: 106 KDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFV 165
++TG ++VT LDRE + L D G +E P+ L + V+D NDN P+F + ++
Sbjct: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
Query: 166 GSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEP--AYPPVFYLNKDTGEIYT- 222
G V E S T VM++ A DAD+P T N+ + Y I P P +FY++ + G+I T
Sbjct: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
Query: 223 -TSVTLDRE--EHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEG 279
+ LDRE E+ Y L +EA+D G + A I I D ND+ P K +
Sbjct: 312 VSPALLDRETLENPKYELIIEAQDMAG-LDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
Query: 280 MVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKE 339
VEE V V + + V D D+ + W A +T +GN G F I T+ QTNEG+++++K
Sbjct: 371 TVEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKP 429
Query: 340 VDYEEMKNLDFSVIVANKAAFHKSIRSKYKP-TPIPIKVKVKNVKEGIHFKSSVISIYVS 398
+DYE + V N+ + Y P + + + V +V EG F + +
Sbjct: 430 LDYEISAFHTLLIKVENEDPLVPDV--SYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQ 487
Query: 399 ESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESR 458
E + S G ++ A D D+ RY +D W++++ + + + D ES
Sbjct: 488 EDL---SVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESP 544
Query: 459 YVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVT-- 516
+V N YT +AI P T TGT+LI +ED+NDN P + V +C DA+ ++V
Sbjct: 545 FVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVIL 604
Query: 517 -AEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDN 575
A D D HPN+ PF F I K + WKI++ +T L+ + L ++ I
Sbjct: 605 GASDKDLHPNTDPFKFE-IHKQAVPDKVWKISKINNTHALVSLLQ-NLNKANYNLPIMVT 662
Query: 576 QGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLL 633
P + L V C CR ++ D A+ + + LLL L L L
Sbjct: 663 DSGKPPMTNITDLRVQVC----SCRNSKVDCNAA---GALRFSLPSVLLLSLFSLACL 713
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 239 bits (611), Expect = 8e-63
Identities = 195/661 (29%), Positives = 311/661 (47%), Gaps = 47/661 (7%)
Query: 1 MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPK------HPHLVRQKRAWITA 54
MA GR +LLLLL+ + + + S + E L K + L R KR W+
Sbjct: 1 MAMRSGRHPSLLLLLVLLLWLLQVSI-IDSVQQETDDLTKQTKEKIYQPLRRSKRRWVIT 59
Query: 55 PVALREGEDLSKKNPIAKIHSDLAEERG--LKITYKYTGKGITE-PPFGIFVF-NKDTGE 110
+ L E + P K+ +L + + Y +G G+ E P G+F + + G
Sbjct: 60 TLELEEEDP----GPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGR 115
Query: 111 LNVTSILDREETPFFLLTGYALD-ARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVE 169
+ V +DRE TP F + ++ + G V+ L I++ D+ND+ P F + F +V+
Sbjct: 116 IYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQ 175
Query: 170 ELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPV-FYLNKDTGEIYTTSVTLD 228
E +A + ++ A D DE NT NS++ Y ++S P F +++ +GEI S LD
Sbjct: 176 ENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEI-RLSGCLD 234
Query: 229 REEHSSYTLTVEARD-GNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVN 287
E +TL + ARD G ++ VQ + N++ P + + + E + +
Sbjct: 235 YETAPQFTLLIRARDCGEPSLSSTTTVHVDVQ----EGNNHRPAFTQENYKVQIPEGRAS 290
Query: 288 VEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKN 347
V R+ V D D + W A F GNE G+F I TD +TNEGI+ +IK +DYE
Sbjct: 291 QGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPA 350
Query: 348 LDFSVIVANKAAFHKSIRSKYKP-------TPIPIKVKVKNVKEGIHFKSSVISIYVSES 400
++V N+ R K +P + ++V N H +S +++
Sbjct: 351 QSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVN-----K 405
Query: 401 MDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYV 460
+ + G ++G F A D D+ + RY + D NW+SVD + + + D ES +V
Sbjct: 406 EEGARPGTLLGTFNAMDPDSQI----RYELVHDPANWVSVDKNSGVVITVEPIDRESPHV 461
Query: 461 QNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTL--IEPVQTICHDA--EYVNVT 516
N Y + I A+ + +P +T TGT+++ + DINDN PTL +C A E +++
Sbjct: 462 NNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIE 521
Query: 517 AEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSV-LLQQSEKKLGRSEIQFLISDN 575
AED D P S PF+F + + + WK+ R SV LL G + I D
Sbjct: 522 AEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDK 581
Query: 576 QGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMC 635
QG S +KQ + + +C C G C E D+ VGL A+ + AF+ L + L LL C
Sbjct: 582 QGLS--QKQTVHVRICPCASGLTCVELA-DAEVGLHVGALFPVCAAFVALAVALLFLLRC 638
Query: 636 H 636
+
Sbjct: 639 Y 639
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 215 bits (547), Expect = 2e-55
Identities = 191/640 (29%), Positives = 300/640 (46%), Gaps = 41/640 (6%)
Query: 11 LLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI 70
L+ L +CF SG+ LS R KR+W+ + E S +
Sbjct: 14 LIALFLCF---SGMSQAELSRSRSKPYFQSGRS--RTKRSWVWNQFFVLEEYMGSDPLYV 68
Query: 71 AKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGY 130
K+HSD+ + G I Y +G+G + IF+ +++TG+++ T LDREE ++ L
Sbjct: 69 GKLHSDVDKGDG-SIKYILSGEGASS----IFIIDENTGDIHATKRLDREEQAYYTLRAQ 123
Query: 131 ALDARGNN-VEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEP 189
ALD N VE E IK+ DINDNEP F + V E+S T V+++ ATDAD+P
Sbjct: 124 ALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDP 183
Query: 190 NTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEV 248
NS ++ Y I+ + P F + TG I T +DRE Y L ++A+D G+
Sbjct: 184 TYGNSARVVYSILQGQ----PYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQ- 238
Query: 249 TDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEEN-QVNVEVTRIKVFDADEIGSDNWL 307
V + + DVNDN P + + V E+ V V RIK DAD IG+ N
Sbjct: 239 NGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADAD-IGA-NAE 296
Query: 308 ANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSK 367
+ G+ G F I D +T EGI+T+ KE+D+E + + ANK A + +
Sbjct: 297 MEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLG 356
Query: 368 YKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDED-TGLPAHA 426
+K+ V++V E F S + + VSE+ + G IIG A D D + P
Sbjct: 357 PFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEA---TQVGNIIGTVAAHDPDSSNSPVRY 413
Query: 427 RYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVL 486
+ D + + ++D+ + I AK D E+ N + + ++A+ P + G V
Sbjct: 414 SIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIHNITVLAMESQNPSQVGRGYVA 469
Query: 487 INVEDINDNCPTL-IEPVQTICHDAE----YVNVTAEDLDGHPNSGPFSFSV-IDKPPGM 540
I + DINDN P ++ T+C +A+ ++A D D N F FS+ D
Sbjct: 470 ITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNH 529
Query: 541 AEKWKIARQESTSVLLQQSEKKLGRSEIQFL---ISDNQGFSCPEKQVLTLTVCECLHGS 597
K + + S+L +++ + + +L I D+ S LT+ VC+C
Sbjct: 530 NFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADG 589
Query: 598 GCREAQHDSYV---GLGPAAIALMILAFLLLLLVPLLLLM 634
+ ++YV GL A+ + ILA +L LLV +LL++
Sbjct: 590 VAQTCNAEAYVLPAGLSTGAL-IAILACVLTLLVLILLIV 628
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 215 bits (547), Expect = 2e-55
Identities = 191/640 (29%), Positives = 300/640 (46%), Gaps = 41/640 (6%)
Query: 11 LLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI 70
L+ L +CF SG+ LS R KR+W+ + E S +
Sbjct: 14 LIALFLCF---SGMSQAELSRSRSKPYFQSGRS--RTKRSWVWNQFFVLEEYMGSDPLYV 68
Query: 71 AKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGY 130
K+HSD+ + G I Y +G+G + IF+ +++TG+++ T LDREE ++ L
Sbjct: 69 GKLHSDVDKGDG-SIKYILSGEGASS----IFIIDENTGDIHATKRLDREEQAYYTLRAQ 123
Query: 131 ALDARGNN-VEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEP 189
ALD N VE E IK+ DINDNEP F + V E+S T V+++ ATDAD+P
Sbjct: 124 ALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDP 183
Query: 190 NTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEV 248
NS ++ Y I+ + P F + TG I T +DRE Y L ++A+D G+
Sbjct: 184 TYGNSARVVYSILQGQ----PYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQ- 238
Query: 249 TDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEEN-QVNVEVTRIKVFDADEIGSDNWL 307
V + + DVNDN P + + V E+ V V RIK DAD IG+ N
Sbjct: 239 NGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADAD-IGA-NAE 296
Query: 308 ANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSK 367
+ G+ G F I D +T EGI+T+ KE+D+E + + ANK A + +
Sbjct: 297 MEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLG 356
Query: 368 YKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDED-TGLPAHA 426
+K+ V++V E F S + + VSE+ + G IIG A D D + P
Sbjct: 357 PFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEA---TQVGNIIGTVAAHDPDSSNSPVRY 413
Query: 427 RYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVL 486
+ D + + ++D+ + I AK D E+ N + + ++A+ P + G V
Sbjct: 414 SIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIHNITVLAMESQNPSQVGRGYVA 469
Query: 487 INVEDINDNCPTL-IEPVQTICHDAE----YVNVTAEDLDGHPNSGPFSFSV-IDKPPGM 540
I + DINDN P ++ T+C +A+ ++A D D N F FS+ D
Sbjct: 470 ITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNH 529
Query: 541 AEKWKIARQESTSVLLQQSEKKLGRSEIQFL---ISDNQGFSCPEKQVLTLTVCECLHGS 597
K + + S+L +++ + + +L I D+ S LT+ VC+C
Sbjct: 530 NFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADG 589
Query: 598 GCREAQHDSYV---GLGPAAIALMILAFLLLLLVPLLLLM 634
+ ++YV GL A+ + ILA +L LLV +LL++
Sbjct: 590 VAQTCNAEAYVLPAGLSTGAL-IAILACVLTLLVLILLIV 628
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 202 bits (515), Expect = 1e-51
Identities = 188/678 (27%), Positives = 311/678 (45%), Gaps = 45/678 (6%)
Query: 12 LLLLICFN---VGSGLHLQVLSTRNENKLLPKHPHLV-RQKRAWITAPVALREGEDLSKK 67
+L+ +CF G+ H + RN+ K + + R KR W+ + E
Sbjct: 12 VLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDP 71
Query: 68 NPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLL 127
+ K+HS+ + G + Y TG+G IF+ + TG+++ T LDRE+ ++L
Sbjct: 72 QYVGKLHSNSDKGDG-SVKYILTGEGAGT----IFIIDDTTGDIHSTKSLDREQKTHYVL 126
Query: 128 TGYALDARGNN-VEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDA 186
A+D R N +E E IKV DINDN P FT ++ +V E+S T V+++ ATDA
Sbjct: 127 HAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDA 186
Query: 187 DEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGN 245
D+P NS ++ Y I+ + P F ++ TG I T +DRE Y++ ++A+D
Sbjct: 187 DDPTYGNSARVVYSILQGQ----PYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMA 242
Query: 246 GEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEEN-QVNVEVTRIKVFDADEIGSD 304
G+V V I + DVNDN P K + V E+ QV V +IK DAD
Sbjct: 243 GQVGGLS-GSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADT--GS 299
Query: 305 NWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVAN-KAAFHKS 363
N ++ +G+ G F I TD +T EGI++L K ++YE+ K+ ++ AN F S
Sbjct: 300 NADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFS 359
Query: 364 IRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDT--G 421
+K + +K+ V +V E F + Y+ E + + G ++G A D D+
Sbjct: 360 HLGPFKDATM-LKIIVGDVDEPPLFS---MPSYLMEVYENAKIGTVVGTVLAQDPDSTNS 415
Query: 422 LPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTI 481
L + +ED D + ++D+ T I+ K+ D E + Y + + A D P
Sbjct: 416 LVRYFINYNVED-DRFFNIDANTGTIRTTKVLDRE----ETPWYNITVTASEIDNPDLLS 470
Query: 482 TGTVLINVEDINDNCPTLIEPVQTI-CHDAE----YVNVTAEDLDGHPNSGPFSFSVIDK 536
TV I V D+NDN P L I C +++ ++A D D N F+F + ++
Sbjct: 471 HVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDER 530
Query: 537 PPGMAEKWKIARQESTSVLLQQSEKKLGRS-----EIQFLISDNQGFSCPEKQVLTLTVC 591
P + + + E + + ++ R+ + +ISD S LT+ VC
Sbjct: 531 LP-VNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVC 589
Query: 592 ECLHGSGCREAQHDSYV---GLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIP 648
C R ++++ GL A+ ++L L+LL + +L + K
Sbjct: 590 ACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEE 649
Query: 649 GTIEMLHPWNNEGAPPED 666
E + +++EG ED
Sbjct: 650 DVRENVVTYDDEGGGEED 667
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 199 bits (505), Expect = 2e-50
Identities = 165/604 (27%), Positives = 279/604 (46%), Gaps = 35/604 (5%)
Query: 44 LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFV 103
L R KR+W+ L E S + K+HSD G + Y +G G + +F+
Sbjct: 48 LNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDG-SLKYILSGDGAGD----LFI 102
Query: 104 FNKDTGELNVTSILDREETPFFLLTGYALDAR-GNNVEKPLELRIKVLDINDNEPVFTQD 162
N++TG++ T LDREE P ++L A++ R G VE E IK+ DINDNEP+FT++
Sbjct: 103 INENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKE 162
Query: 163 VFVGSVEELSAAHTLVMKINATDADEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIY 221
V+ +V E+S T V+++ ATDAD+P NS K+ Y I+ + P F + +TG I
Sbjct: 163 VYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQ----PYFSVESETGIIK 218
Query: 222 TTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMV 281
T + +DRE Y + ++A+D G++ V I + DVNDN P +
Sbjct: 219 TALLNMDRENREQYQVVIQAKDMGGQMGGLS-GTTTVNITLTDVNDNPPRFPQSTYQFKT 277
Query: 282 -EENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEV 340
E + + RIK DAD +N ++ G F + TD +T EGI+T+ K +
Sbjct: 278 PESSPPGTPIGRIKASDADV--GENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLL 335
Query: 341 DYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSES 400
D+E+ K V +N + + +++ V++V E F Y+ +
Sbjct: 336 DFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLA---YILQI 392
Query: 401 MDRSSKGQIIGNFQAFDEDTGL-PAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRY 459
+ + IG+ A D D P + D D ++DS I +KL D E+
Sbjct: 393 REDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLL 452
Query: 460 VQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQT-ICHDAE----YVN 514
N + ++A + P+++ + I V D+NDN P E +T +C A+
Sbjct: 453 WHN----ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQT 508
Query: 515 VTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQ----SEKKLGRSEIQF 570
+ A D D + FSFS+ + + +++T+ +L + + ++ +
Sbjct: 509 LHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPV 568
Query: 571 LISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYV---GLGPAAIALMILAFLLLLL 627
+ISDN +T+ VC C H + ++ + GL A+ ++L ++LL+
Sbjct: 569 VISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLV 628
Query: 628 VPLL 631
+L
Sbjct: 629 TVVL 632
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 196 bits (499), Expect = 8e-50
Identities = 188/647 (29%), Positives = 286/647 (44%), Gaps = 49/647 (7%)
Query: 12 LLLLICFNVGSGLHLQ-----VLSTR-NENKL-LP-KHPHLVRQKRAWITAPVALREGED 63
LLL + F+ G LQ L+T EN + LP + H R KR W+ + E
Sbjct: 9 LLLWVLFDGGLLTPLQPQPQQTLATEPRENVIHLPGQRSHFQRVKRGWVWNQFFVLEEYV 68
Query: 64 LSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETP 123
S+ + K+HSDL + G T KYT G + +F ++ TG+++ LDREE P
Sbjct: 69 GSEPQYVGKLHSDLDKGEG---TVKYTLSG--DGAGTVFTIDETTGDIHAIRSLDREEKP 123
Query: 124 FFLLTGYALDARGNN-VEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKIN 182
F+ L A+D +E E IKV DINDNEP F +V +V E+S V+++
Sbjct: 124 FYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVK 183
Query: 183 ATDADEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEA 241
ATDAD+P NS ++ Y I+ + P F ++ TG I T +DRE Y + ++A
Sbjct: 184 ATDADDPTYGNSARVVYSILQGQ----PYFSIDPKTGVIRTALPNMDREVKEQYQVLIQA 239
Query: 242 RDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMV-EENQVNVEVTRIKVFDADE 300
+D G++ V I + DVNDN P + V E + + + RI+ D D
Sbjct: 240 KDMGGQLGGL-AGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPD- 297
Query: 301 IGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAF 360
N + G+ G F I TD T EG++ L K +D+E K F V +N
Sbjct: 298 -FGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASNLHLD 356
Query: 361 HKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDT 420
H+ + +K+ V +V E F +Y E + + G IIG A D D
Sbjct: 357 HRFHSAGPFKDTATVKISVLDVDEPPVFSK---PLYTMEVYEDTPVGTIIGAVTAQDLDV 413
Query: 421 GLPAHARYVKLE-DRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRK 479
G A ++ + D D++ ++D I +L D ES Y I+A P
Sbjct: 414 GSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES----TAQYNFSIIASKVSNPLL 469
Query: 480 TITGTVLINVEDINDNCPTLIEPVQT-ICHDAE----YVNVTAEDLDGHPNSGPFSFSVI 534
T +LINV D+N+ P + P +T +C +A+ V+A D D P FSF +
Sbjct: 470 TSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSFRL- 528
Query: 535 DKPPGMAEKWKIA----RQESTSVLLQQSEKKLGRSEIQFL---ISDNQGFSCPEKQVLT 587
P A K R + + +++ + E+ FL I D+ +T
Sbjct: 529 --SPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMT 586
Query: 588 LTVCECLHGS---GCREAQHDSYVGLGPAAIALMILAFLLLLLVPLL 631
+ VC C C VGL A+ ++L ++LL + +L
Sbjct: 587 IRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILLCIVILLAIVVL 633
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 187 bits (474), Expect = 6e-47
Identities = 169/609 (27%), Positives = 271/609 (44%), Gaps = 48/609 (7%)
Query: 44 LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFV 103
L RQKR W+ L E S + K+HSD + G + Y +G G +F+
Sbjct: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDG-SLKYILSGDGAGT----LFI 103
Query: 104 FNKDTGELNVTSILDREETPFFLLTGYALDARG-NNVEKPLELRIKVLDINDNEPVFTQD 162
++ TG+++ T +DREE F+ L A++ R VE E IK+ DINDNEP F ++
Sbjct: 104 IDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEE 163
Query: 163 VFVGSVEELSAAHTLVMKINATDADEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIY 221
++ SV E+S T V+++ ATDAD+P+ NS ++ Y I+ + P F + +TG I
Sbjct: 164 IYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQ----PYFSVEPETGIIR 219
Query: 222 TTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIP-VVENKVLEGM 280
T ++RE Y + ++A+D G++ V I + DVNDN P +N + +
Sbjct: 220 TALPNMNRENREQYQVVIQAKDMGGQMGGLS-GTTTVNITLTDVNDNPPRFPQNTIHLRV 278
Query: 281 VEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEV 340
+E + V + +K DAD N + G+ F I T+ T EGI+T+ K +
Sbjct: 279 LESSPVGTAIGSVKATDADT--GKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPL 336
Query: 341 DYEEMKNLDFSVIVANKAAFHKSIRSKY----KPTPIPIKVKVKNVKEGIHFKSSVISIY 396
DYE + V N H R Y K T I +K+ +++V E F S
Sbjct: 337 DYESRRLYTLKVEAENT---HVDPRFYYLGPFKDTTI-VKISIEDVDEPPVFSRSSYLFE 392
Query: 397 VSESMDRSSKGQIIGNFQAFDEDT-GLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDF 455
V E ++ G IIG A D D+ P + D D ++ S + +K D
Sbjct: 393 VHEDIE---VGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDR 449
Query: 456 ESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQT-ICHDAE--- 511
E N T ++A + P++T V + + D+NDN P T +C +A
Sbjct: 450 ELSQWHNLT----VIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQ 505
Query: 512 -YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQ- 569
++A D D F FS+ P + + E + + + R EI
Sbjct: 506 LIQTISAVDKDDPLGGQKFFFSLAAVNP----NFTVQDNEDNTARILTRKNGFNRHEIST 561
Query: 570 ----FLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYV---GLGPAAIALMILAF 622
+ISDN LT+ VC C + ++ + GL A+ ++L
Sbjct: 562 YLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCI 621
Query: 623 LLLLLVPLL 631
++LL++ +L
Sbjct: 622 IILLVIVVL 630
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 184 bits (466), Expect = 5e-46
Identities = 182/659 (27%), Positives = 279/659 (42%), Gaps = 58/659 (8%)
Query: 9 YALLLLLICFNVGSGLHLQVLSTRNENKLLPK-HPH---------LVRQKRAWITAPVAL 58
Y L L+C +G H + L P H H L R KR W+ +
Sbjct: 5 YCLQAALVC--LGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFV 62
Query: 59 REGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILD 118
E + ++HSD+ G I Y +G+G IFV + +G ++ T LD
Sbjct: 63 IEEYTGPDPVLVGRLHSDIDSGDG-NIKYILSGEGAGT----IFVIDDKSGNIHATKTLD 117
Query: 119 REETPFFLLTGYALDARGNN-VEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTL 177
REE + L A+D N +E P E +KV DINDN P F + + +V E S T
Sbjct: 118 REERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTS 177
Query: 178 VMKINATDADEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYT 236
V+++ A+DAD+P NS K+ Y I+ + P F + TG I T +DRE Y
Sbjct: 178 VIQVTASDADDPTYGNSAKLVYSILEGQ----PYFSVEAQTGIIRTALPNMDREAKEEYH 233
Query: 237 LTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQV-NVEVTRIKV 295
+ ++A+D G + +V I + DVNDN P V + V E V EV R+K
Sbjct: 234 VVIQAKDMGGHMGGLS-GTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKA 292
Query: 296 FDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVA 355
D D IG +N L + G+ F I TD +T EG++ L K VD+E + V A
Sbjct: 293 KDPD-IG-ENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAA 350
Query: 356 NKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQA 415
N K I + + +K+ V++ E F + Y+ E + ++ G ++G A
Sbjct: 351 NVHIDPKFISNGPFKDTVTVKISVEDADEPPMF---LAPSYIHEVQENAAAGTVVGRVHA 407
Query: 416 FDED-TGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISE 474
D D P + D D + +++ IK K D E + + + A
Sbjct: 408 KDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----ETAWLNITVFAAEI 463
Query: 475 DYPRKTITGTVLINVEDINDNCPTLIEPVQ-TICHDAE--------YVNVTAEDLDGHPN 525
+ V I V D+NDN P P + IC + V ++A+D D N
Sbjct: 464 HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTAN 523
Query: 526 SGPFSFSVIDKPPGMAEKWKIA----RQESTSVLLQQ---SEKKLGRSEIQFLISDNQGF 578
F FS+ PP + R + V ++ S +K + +ISD
Sbjct: 524 GPRFIFSL---PPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIP 580
Query: 579 SCPEKQVLTLTVCECLHGSGCREAQHDSYV---GLGPAAIALMILAFLLLLLVPLLLLM 634
LT+ VC C ++Y+ GL A+ + ILA +++LLV ++L +
Sbjct: 581 PMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGAL-IAILACIVILLVIVVLFV 638
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 183 bits (464), Expect = 9e-46
Identities = 165/622 (26%), Positives = 280/622 (45%), Gaps = 51/622 (8%)
Query: 31 TRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYT 90
T+++ K+L R KR W+ L E + + K+H+D + G + Y T
Sbjct: 41 TKDDGKMLR------RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDG-NLKYILT 93
Query: 91 GKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDAR-GNNVEKPLELRIKV 149
G G +FV +++TG+++ LDREE ++L A+D + G VE E IK+
Sbjct: 94 GDGAGS----LFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKI 149
Query: 150 LDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNS-KISYRIVSLEPAYP 208
DINDNEP FT+D++ SV E+S T V+++ ATDAD+ N NS K+ Y I+ +
Sbjct: 150 HDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQ---- 205
Query: 209 PVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDN 268
P F ++ ++G I T + RE Y + ++A+D G++ V I + DVN+N
Sbjct: 206 PYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLS-GTTTVNITLTDVNNN 264
Query: 269 IPVVENKVLE-GMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDA 327
P + E + + RIK D D +N ++ A G+ F + TD
Sbjct: 265 PPRFPQSTYQFNSPESVPLGTHLGRIKANDPDV--GENAEMEYSIAEGDGADMFDVITDK 322
Query: 328 QTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIR-SKYKPTPIPIKVKVKNVKEGI 386
T EGI+T+ + +D+E V +N + + +K T + +K+ V+++ E
Sbjct: 323 DTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAV-VKISVEDIDEPP 381
Query: 387 HFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLE-----DRDNWISVD 441
F I V E + +G IIG A+D D A +K D D +
Sbjct: 382 VFTKVSYLIEVDEDV---KEGSIIGQVTAYDPD----ARNNLIKYSVDRHTDMDRIFGIH 434
Query: 442 SVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIE 501
S I K D ES + + + + A + P+++ V I + DIND+ P
Sbjct: 435 SENGSIFTLKALDRES----SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAM 490
Query: 502 PVQT-ICHDAE----YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLL 556
+T +C +A+ V+ D D P F F + + + +++T+ ++
Sbjct: 491 YYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIM 550
Query: 557 QQ----SEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYV---G 609
+ S K+ + LI DN LT+ VC C + + ++ + G
Sbjct: 551 TRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAG 610
Query: 610 LGPAAIALMILAFLLLLLVPLL 631
L A+ ++L L+LL++ +L
Sbjct: 611 LSTGALVAILLCVLILLILVVL 632
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 173 bits (438), Expect = 9e-43
Identities = 167/639 (26%), Positives = 280/639 (43%), Gaps = 36/639 (5%)
Query: 46 RQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFN 105
R KR W+ + E ++ + KIHSD E G I Y +G+G IF+ +
Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGA-IKYTISGEGAGT----IFLID 113
Query: 106 KDTGELNVTSILDREETPFFLLTGYALDARGNNVEKP-LELRIKVLDINDNEPVFTQDVF 164
+ TG+++ LDRE+ F+ L A D N + +P E IKV DIND+EP F +
Sbjct: 114 ELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPY 173
Query: 165 VGSVEELSAAHTLVMKINATDADEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGEIYTT 223
+GSV ELS T VM++ A+DAD+P +S ++ Y ++ E F ++ TG I T
Sbjct: 174 IGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHH----FTVDPKTGVIRTA 229
Query: 224 SVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEE 283
LDRE Y + ++A D G++ V I + DVNDN P K+ + ++E
Sbjct: 230 VPDLDRESQERYEVVIQATDMAGQLGGLS-GSTTVTIVVTDVNDNPPRFPQKMYQFSIQE 288
Query: 284 N-QVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDY 342
+ + V R+K D+D + + + S + G F + TD+ T E I+ + K +D+
Sbjct: 289 SAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDF 348
Query: 343 EEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMD 402
E + NK + ++V V +V E F+ + V E
Sbjct: 349 ESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQED-- 406
Query: 403 RSSKGQIIGNFQAFDED-TGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQ 461
+ G ++G A D D P + D D +D+ T I K D E+
Sbjct: 407 -AQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETA--- 462
Query: 462 NGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQ-TICHDAE----YVNVT 516
G + + ++A+ D + ++ I + D+NDN P L P + +C DA+ ++
Sbjct: 463 -GWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTIS 521
Query: 517 AEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSE-----IQFL 571
D D F F ++ + P + Q++T+ + Q R E + L
Sbjct: 522 VVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQ-HVGFNRQEQDVFFLPIL 580
Query: 572 ISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYV---GLGPAA-IALMILAFLLLLL 627
+ D+ + LT+ +C C + ++V L P A IAL++ +L++L
Sbjct: 581 VVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVL 640
Query: 628 VPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPED 666
V L+L + K + + +N+EG +D
Sbjct: 641 VLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQD 679
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 172 bits (436), Expect = 2e-42
Identities = 179/635 (28%), Positives = 283/635 (44%), Gaps = 54/635 (8%)
Query: 22 SGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI--AKIHSDLAE 79
SG L++ S E ++L R KR W+ + + E + S PI ++H+DL +
Sbjct: 40 SGSPLELNSLGEEQRILN------RSKRGWVWNQMFVLE--EFSGPEPILVGRLHTDL-D 90
Query: 80 ERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNN- 138
KI Y +G G IF N TG+++ LDREE + LT A+D +
Sbjct: 91 PGSKKIKYILSGDGAGT----IFQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKP 146
Query: 139 VEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNS-KIS 197
+E P E IKV DINDN P F + +V E+S T V + ATDAD+P NS K+
Sbjct: 147 LEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLV 206
Query: 198 YRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQ 257
Y I+ + P F + +T I T +DRE Y + ++A+D G +
Sbjct: 207 YSILEGQ----PYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGH-SGGLSGTTT 261
Query: 258 VQIRILDVNDNIPVVENKVLEGMVEENQV-NVEVTRIKVFDADEIGSDNWLANFTFASGN 316
+ + + DVNDN P + V E+ V + R+K D D IG +N +++ G+
Sbjct: 262 LTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQD-IG-ENAQSSYDIIDGD 319
Query: 317 EGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHK-SIRSKYKPTPIPI 375
F I +DAQ +GI+ L K +D+E K+ V AN + S R +K T +
Sbjct: 320 GTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDT-ATV 378
Query: 376 KVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDED-TGLPAHARYVKLEDR 434
K+ V++ E F S Y+ E + ++ +IG A D D T P + D
Sbjct: 379 KIVVEDADEPPVFSSPT---YLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDL 435
Query: 435 DNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDIND 494
+ ++++ +I LA D E N + I+A + V I V D+ND
Sbjct: 436 ERQFNINADDGKITLATPLDRELSVWHN----ITIIATEIRNHSQISRVPVAIKVLDVND 491
Query: 495 NCPTLIEPVQT-ICHDAE----YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAE--KWKIA 547
N P + +C + + V+A D D N F +S++ P M + I
Sbjct: 492 NAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLL---PEMVNNPNFTIK 548
Query: 548 RQESTSVLLQQSEKKLGRSE-----IQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREA 602
+ E S+ + R + + +ISD+ LT+ VC C + +
Sbjct: 549 KNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSC 608
Query: 603 QHDSYV---GLGPAAIALMILAFLLLLLVPLLLLM 634
++YV GL A+ + ILA ++LLLV ++L +
Sbjct: 609 NVEAYVLPIGLSMGAL-IAILACIILLLVIVVLFV 642
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 168 bits (425), Expect = 3e-41
Identities = 170/642 (26%), Positives = 269/642 (41%), Gaps = 39/642 (6%)
Query: 42 PHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGI 101
P L+R +R+W+ + E + I K+HSD+ G + Y TG+G +
Sbjct: 37 PALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEG-RTKYLLTGEGAGT----V 91
Query: 102 FVFNKDTGELNVTSILDREETPFFLLTGYALDARGNN-VEKPLELRIKVLDINDNEPVFT 160
FV ++ TG ++VT LDREE ++L A+D N +E P E IKV DINDN P+F
Sbjct: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFP 151
Query: 161 QDVFVGSVEELSAAHTLVMKINATDADEPNTLNS-KISYRIVSLEPAYPPVFYLNKDTGE 219
+ +V E+S T V+++ A DAD+P+ NS K+ Y ++ P F ++ TG
Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLD----GLPFFSVDPQTGV 207
Query: 220 IYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLE- 278
+ T +DRE + + ++A+D G + V + + DVNDN P + +
Sbjct: 208 VRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS-GSTTVTVTLSDVNDNPPKFPQSLYQF 266
Query: 279 GMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIK 338
+VE V R++ D D DN L ++ G F I TD Q +G++T+ K
Sbjct: 267 SVVETAGPGTLVGRLRAQDPDL--GDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRK 324
Query: 339 EVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVS 398
+D+E ++ F V N +R ++V V++ E F + + V
Sbjct: 325 PLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVP 384
Query: 399 ESMDRSSKGQIIGNFQAFDEDT-GLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFES 457
E+ + G ++G A D D+ P + D + S+ I A D E+
Sbjct: 385 EN---KAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA 441
Query: 458 RYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVN--- 514
R N T ++A D + V I D NDN P L EP T D+
Sbjct: 442 RAWHNLT----VLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLI 497
Query: 515 --VTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLI 572
+ A D D NS SF P G + + S L + +L+
Sbjct: 498 QVIRALDRDEVGNSSHVSF---QGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLV 554
Query: 573 S----DNQGFSCPEKQVLTLTVCECLHG---SGCREAQHDSYVGLGPAA-IALMILAFLL 624
D + +T++VC C + C H S GL A +A++ L
Sbjct: 555 PIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGAL 614
Query: 625 LLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPED 666
L LV L + + + A E + +++EG ED
Sbjct: 615 LALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEED 656
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 167 bits (424), Expect = 4e-41
Identities = 210/829 (25%), Positives = 343/829 (41%), Gaps = 109/829 (13%)
Query: 32 RNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTG 91
R+ + LLP H RQKR WI + + E ++ S + + KI S ++ + KY
Sbjct: 33 RDTHSLLPTHR---RQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNA-----KYLL 84
Query: 92 KGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDA-RGNNVEKPLELRIKVL 150
KG E +F + +TG++ LDRE + LT +D G N+E P IKV
Sbjct: 85 KG--EYVGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVH 142
Query: 151 DINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNT-LNSKISYRIVSLEPAYPP 209
D+NDN PVFT +F SV E SA T V+ + A DAD+P ++ + Y+I+ +
Sbjct: 143 DVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKE---- 198
Query: 210 VFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNI 269
++ ++G I T + +LDRE+ + Y + VEARD G D A V + + D+NDN
Sbjct: 199 -YFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGT--ATVLVTLQDINDNF 255
Query: 270 P-VVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQ 328
P + K + E+ +V V + V D DE N + ++ G+ F IET+
Sbjct: 256 PFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDE--PQNRMTKYSILRGDYQDAFTIETNPA 313
Query: 329 TNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTP----IPIKVKVKNVKE 384
NEGI+ +K +DYE ++ F V A +I +Y P + + + +V E
Sbjct: 314 HNEGIIKPMKPLDYEYIQQYSFIV-----EATDPTIDLRYMSPPAGNRAQVIINITDVDE 368
Query: 385 GIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYV-KLEDRDNWISVDSV 443
F+ + E + K +IG A D D + + + D+ + V +
Sbjct: 369 PPIFQQPFYHFQLKE----NQKKPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRV-TK 423
Query: 444 TSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPV 503
+I K D E N T K + + K V I V D NDN P +P
Sbjct: 424 KGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPY 483
Query: 504 Q-TICHDAEY----VNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQ 558
Q +C +A + + ++A D D P + F F +++ + +V Q
Sbjct: 484 QPKVCENAVHGQLVLQISAIDKDITPRNVKFKF-ILNTENNFTLTDNHDNTANITVKYGQ 542
Query: 559 SEKKLGRSEIQFL---ISDNQGFSCPEKQVLTLTVCEC-LHGSGCREAQHDSYVGLGPAA 614
+++ +++ FL ISDN S LT+ VC+C G + VG+ A
Sbjct: 543 FDRE--HTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQA 600
Query: 615 IALMILAFLLLLLVPLLL-LMCHCGKGAKGF-TPIPGTIEMLHPWNNEGAPPEDKVVPSF 672
+ ++L L + ++ LL+ L K A+ +P E L ++ EG D
Sbjct: 601 VVAILLCILTITVITLLIFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTT---- 656
Query: 673 LPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQF 732
S S++ S G + R L R + +
Sbjct: 657 --------------------------SYDVSVLN-----SVRRGGAKPPRPALDARPSLY 685
Query: 733 TGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTA 792
+ K R + G AA + + ++ + D +
Sbjct: 686 ---------AQVQKPPRHAPGAHGGPGEMAAMIEVKKD------------EADHDGDGPP 724
Query: 793 KDCLLVYSQEETESLNASIGC--CSFIEGELDDRFLDDLGLKFKTLAEV 839
D L +Y E +ES+ S+ + ++D FL+D G +FK LAE+
Sbjct: 725 YDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAEL 773
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,134,680
Number of Sequences: 37866
Number of extensions: 1971741
Number of successful extensions: 7728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 4201
Number of HSP's gapped (non-prelim): 1296
length of query: 1118
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1005
effective length of database: 13,968,660
effective search space: 14038503300
effective search space used: 14038503300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.