Guide to the Human Genome
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Search of human proteins with 239744140

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]
         (878 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]          1817   0.0  
gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo sap...  1797   0.0  
gi|150170710 hypothetical protein LOC728118 [Homo sapiens]           1774   0.0  
gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo sap...  1283   0.0  
gi|148806874 hypothetical protein LOC54754 [Homo sapiens]            1282   0.0  
gi|57528101 hypothetical protein LOC728130 [Homo sapiens]            1090   0.0  
gi|113865921 hypothetical protein LOC441457 [Homo sapiens]            864   0.0  
gi|50233787 nuclear protein in testis [Homo sapiens]                  468   e-132
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    58   3e-08
gi|110349719 titin isoform N2-A [Homo sapiens]                         54   5e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          53   1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          53   1e-06
gi|226437579 NAC alpha domain containing [Homo sapiens]                52   2e-06
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]     52   2e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     52   3e-06
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    51   4e-06
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]     50   7e-06
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]     50   7e-06
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]     50   7e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    50   9e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    49   2e-05
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 49   2e-05
gi|223633988 hypothetical protein LOC85379 [Homo sapiens]              48   3e-05
gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo ...    48   3e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         48   3e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   6e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   6e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   6e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   6e-05
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    47   6e-05

>gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 878

 Score = 1817 bits (4706), Expect = 0.0
 Identities = 878/878 (100%), Positives = 878/878 (100%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
           FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDV 660
           LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDV
Sbjct: 601 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDV 660

Query: 661 PDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQD 720
           PDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQD
Sbjct: 661 PDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQD 720

Query: 721 HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP 780
           HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP
Sbjct: 721 HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP 780

Query: 781 VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGL 840
           VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGL
Sbjct: 781 VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGL 840

Query: 841 RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
           RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ
Sbjct: 841 RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878


>gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 878

 Score = 1797 bits (4655), Expect = 0.0
 Identities = 868/878 (98%), Positives = 873/878 (99%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
           FPSTPLVTEQDGC PSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 FPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPP+PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDV 660
           LALSQDLEQEEGLTLAQLVEKRLPPLKEKQH+RAAPSRGTARLDSSSSKFAAGQGAERDV
Sbjct: 601 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDV 660

Query: 661 PDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQD 720
           PDPQ+GVGMETCPPQ TARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAA PTSPPQD
Sbjct: 661 PDPQQGVGMETCPPQMTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAAWPTSPPQD 720

Query: 721 HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP 780
           HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP
Sbjct: 721 HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP 780

Query: 781 VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGL 840
           VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKK+PLFGSLSPAEKTP+ GPGL
Sbjct: 781 VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPYPGPGL 840

Query: 841 RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
           RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ
Sbjct: 841 RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878


>gi|150170710 hypothetical protein LOC728118 [Homo sapiens]
          Length = 878

 Score = 1774 bits (4596), Expect = 0.0
 Identities = 857/878 (97%), Positives = 866/878 (98%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMA+ALHR SPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAKALHRMSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYP LGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
            PSTPLVTEQDGC PSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 LPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGE SLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPP+PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEG+VKQPQEEDWTPPDPGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDV 660
           LALSQ+LEQEEGLTLAQLVEKRL PLKEKQH+RAAPSRGTARLDSSSSKFAAGQGAERDV
Sbjct: 601 LALSQELEQEEGLTLAQLVEKRLLPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDV 660

Query: 661 PDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQD 720
           P PQ+GVGMETCPPQTTARDSQGRGRAHTGMARS+DSVVLLGCQDSPGLRAARPTSPPQD
Sbjct: 661 PVPQQGVGMETCPPQTTARDSQGRGRAHTGMARSKDSVVLLGCQDSPGLRAARPTSPPQD 720

Query: 721 HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP 780
           HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP
Sbjct: 721 HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP 780

Query: 781 VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGL 840
           VPASGLLSPEKWGPQGTHQ PSAERRGLNLAPSPANKAKK+PLFGSLSPAEKTPH GPGL
Sbjct: 781 VPASGLLSPEKWGPQGTHQFPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPHPGPGL 840

Query: 841 RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
           RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQ CSQ
Sbjct: 841 RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQRCSQ 878


>gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 629

 Score = 1283 bits (3319), Expect = 0.0
 Identities = 617/617 (100%), Positives = 617/617 (100%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
           FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQ 617
           LALSQDLEQEEGLTLAQ
Sbjct: 601 LALSQDLEQEEGLTLAQ 617


>gi|148806874 hypothetical protein LOC54754 [Homo sapiens]
          Length = 756

 Score = 1282 bits (3317), Expect = 0.0
 Identities = 632/757 (83%), Positives = 670/757 (88%), Gaps = 2/757 (0%)

Query: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
           MASNGAYPVLGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA  PP GPLVLS FP
Sbjct: 1   MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60

Query: 183 STPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
           STPLV  QDG  PSGAGASNVFVQMRTEVGPVK  QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 61  STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120

Query: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
           CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179

Query: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
           QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239

Query: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
           VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299

Query: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRP 481
           KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKA TACLPPPRPQRP  TKA  P
Sbjct: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359

Query: 482 PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
           PP+P R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG   G TGEPE Q
Sbjct: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419

Query: 542 REEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 601
           RE+GKV+QPQEED    DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479

Query: 602 ALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVP 661
           ALSQ+LEQEEGLTLAQLVEKRL  LKEK   RAAP  GTARLDSS S+FAAGQ A R+VP
Sbjct: 480 ALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVP 539

Query: 662 DPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQDH 721
           DPQ+ V +ET PPQT A+D QG+GR  TGMARSED  VLLGCQDSP L+A RPTSPPQDH
Sbjct: 540 DPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDH 599

Query: 722 RPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPV 781
           RPTCPG+GTKDAL LPG SPV+ESHGLA+GSSEE ELP + +++GS H+L PW L QSPV
Sbjct: 600 RPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPV 659

Query: 782 PASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGLR 841
           P+SGLLSP   GPQG  QSPSA++RGL+ +PSPA+K+KK+PLFGS SPAEKTPH GPGLR
Sbjct: 660 PSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLR 719

Query: 842 VSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
           VSGEQSL WGLGGPSQSQKRKGDPL SR++KK+HCSQ
Sbjct: 720 VSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756


>gi|57528101 hypothetical protein LOC728130 [Homo sapiens]
          Length = 557

 Score = 1090 bits (2819), Expect = 0.0
 Identities = 524/538 (97%), Positives = 529/538 (98%)

Query: 80  FKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTAN 139
           F+  LFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQPEGMASNGAYP LGPGVTAN
Sbjct: 8   FQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 67

Query: 140 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAG 199
           PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLS FPSTPLVTEQDGC PSGAG
Sbjct: 68  PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAG 127

Query: 200 ASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 259
           ASNVFVQMRTEVGPVKAAQAQTLVLTQ PLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA
Sbjct: 128 ASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 187

Query: 260 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAP 319
           AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE SLASSQAKAP
Sbjct: 188 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247

Query: 320 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 379
           PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG
Sbjct: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 307

Query: 380 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 439
           LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR
Sbjct: 308 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 367

Query: 440 GPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPR 499
           GPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARRPPP+PHRRAETKARLPPPR
Sbjct: 368 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 427

Query: 500 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
           PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG+VKQPQEEDWTPPD
Sbjct: 428 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487

Query: 560 PGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQ 617
           PGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQ+LEQEEGLTLAQ
Sbjct: 488 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQ 545


>gi|113865921 hypothetical protein LOC441457 [Homo sapiens]
          Length = 492

 Score =  864 bits (2233), Expect = 0.0
 Identities = 428/495 (86%), Positives = 439/495 (88%), Gaps = 15/495 (3%)

Query: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
           MASNGAYPVLGPGVT NPGTSLSVFTALPF TP+PGP H P LVTA  PP GPLVLS FP
Sbjct: 1   MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPSPGPTHRPPLVTAVVPPAGPLVLSAFP 60

Query: 183 STPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
           STPLV  QDG  PSGAGASNVFVQMRTEVGPVK  QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 61  STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120

Query: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
           CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNAGPWP
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNAGPWP 179

Query: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
           QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239

Query: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
           VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMA KFLEFEAEEEMQIQKSQWM
Sbjct: 240 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAAKFLEFEAEEEMQIQKSQWM 299

Query: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKA TACLPPPRPQRP        
Sbjct: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRP-------- 351

Query: 483 PQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQR 542
                 AETKA LPPPRP RPAETKVPEEIPPEVVQEYVDIMEELLG   G TGEPE QR
Sbjct: 352 ------AETKAHLPPPRPPRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 405

Query: 543 EEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLA 602
           E+GKV+QPQEED    DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFLA
Sbjct: 406 EKGKVEQPQEEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 465

Query: 603 LSQDLEQEEGLTLAQ 617
           LSQ+LEQEEGLTLAQ
Sbjct: 466 LSQELEQEEGLTLAQ 480


>gi|50233787 nuclear protein in testis [Homo sapiens]
          Length = 1132

 Score =  468 bits (1205), Expect = e-132
 Identities = 293/587 (49%), Positives = 357/587 (60%), Gaps = 53/587 (9%)

Query: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAP-------PGGP 175
           MAS+GA  + GP ++  P  +LS   ALPF  P   P   P       P       P  P
Sbjct: 1   MASDGASALPGPDMSMKPSAALSPSPALPFLPPTSDPPDHPPREPPPQPIMPSVFSPDNP 60

Query: 176 LVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPG 235
           L+LS FPS+ LVT   G   SGAGA  V V+++TE G  + +Q Q  +LTQ  L   APG
Sbjct: 61  LMLSAFPSSLLVTGDGGPCLSGAGAGKVIVKVKTEGGSAEPSQTQNFILTQTALNSTAPG 120

Query: 236 ALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQ 295
             CGG+  P P  + A+ V  ++ ++ VG +Q  EG    GLP P PPPP AQL PIV  
Sbjct: 121 TPCGGLEGPAPPFVTASNVKTILPSKAVGVSQ--EG--PPGLP-PQPPPPVAQLVPIVPL 175

Query: 296 GNAGPWPQGAHGESSLASSQAKAPPDDSCN-PRSVYENFRLWQHYKPLARRHLPQSPDTE 354
             A P P G  GE    ++ +K    D     + VYENFR WQ YK LARRHL QSPDTE
Sbjct: 176 EKAWPGPHGTTGEGGPVATLSKPSLGDRSKISKDVYENFRQWQRYKALARRHLSQSPDTE 235

Query: 355 ALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEM 414
           ALSCFLIPVLRSLAR KPTMTLEEGL  A++EW+HTSNFDRMIFYEMAE+F+EFEA EEM
Sbjct: 236 ALSCFLIPVLRSLARLKPTMTLEEGLPLAVQEWEHTSNFDRMIFYEMAERFMEFEA-EEM 294

Query: 415 QIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRP 474
           QIQ +Q M G Q L P    +L+P GP A EV +QPVY+P KA  K +        P+R 
Sbjct: 295 QIQNTQLMNGSQGLSPATPLKLDPLGPLASEVCQQPVYIPKKAASKTRA-------PRRR 347

Query: 475 VTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGA 534
             KA+RPP                        + P+EIPPE V+EYVDIME L+G  L A
Sbjct: 348 QRKAQRPP----------------------APEAPKEIPPEAVKEYVDIMEWLVGTHL-A 384

Query: 535 TGEPE-KQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLS 593
           TGE + KQ EEG   Q QEE+   PDPGLLSYI++LCSQK FV+KVEAVIHPQFL +LLS
Sbjct: 385 TGESDGKQEEEG---QQQEEEGMYPDPGLLSYINELCSQKVFVSKVEAVIHPQFLADLLS 441

Query: 594 PDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSS---KF 650
           P+ Q D LAL ++LEQEEGLTLAQLV+KRL  L+E++ + A PS   A+LDSS S   + 
Sbjct: 442 PEKQRDPLALIEELEQEEGLTLAQLVQKRLMALEEEEDAEAPPSFSGAQLDSSPSGSVED 501

Query: 651 AAGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDS 697
             G G  R  P  Q G G   C  + ++   + R   H G  ++ DS
Sbjct: 502 EDGDGRLRPSPGLQ-GAGGAACLGKVSSSGKRAR-EVHGGQEQALDS 546



 Score = 96.7 bits (239), Expect = 9e-20
 Identities = 73/223 (32%), Positives = 109/223 (48%), Gaps = 17/223 (7%)

Query: 667  VGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQDHRPTCP 726
            V  +TCP    + D QG GR    +++ ++   L   Q+S      + TS  Q    T P
Sbjct: 916  VSEDTCPLNVHSYDPQGEGRVDPDLSKPKNLAPLQESQESYTTGTPKATSSHQGLGSTLP 975

Query: 727  GVGTKDALDLPGGSPVRESHGLA-----------QGSSEEEELPSLAFLLGSQHKLLPWW 775
              GT++A+ +P  + V ++H  A           +   E+EEL + A+LL S+  L P  
Sbjct: 976  RRGTRNAI-VPRETSVSKTHRSADRAKGKEKKKKEAEEEDEELSNFAYLLASKLSLSPRE 1034

Query: 776  LPQSPVPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPH 835
             P SP  ASG    ++     +H  P A  +G +  P P  K+ K+ L G  +P EKTPH
Sbjct: 1035 HPLSPHHASGGQGSQR----ASHLLP-AGAKGPSKLPYPVAKSGKRALAGGPAPTEKTPH 1089

Query: 836  RGPGLRVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
             G  L V  E+ L  G+  PSQ +KR+ D  V+ + KK+  SQ
Sbjct: 1090 SGAQLGVPREKPLALGVVRPSQPRKRRCDSFVTGRRKKRRRSQ 1132


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 115/444 (25%), Positives = 152/444 (34%), Gaps = 94/444 (21%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKAR---RP 481
           P  LPPP+T    P  PP P  V  P  LPS   P AQ      P P  P T +R   RP
Sbjct: 414 PPPLPPPSTSPPPPLCPPPPPPVSPPP-LPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472

Query: 482 PPQPHRRAETKAR------LPPPRPQRPAETKVPEEIPPEVVQE---YVDIMEELLGPSL 532
           P  P +RAE +A         PP P     T  P E  P V  +   ++  + + + P +
Sbjct: 473 PLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVV 532

Query: 533 GATGEPEKQREEGKVKQPQE-EDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEEL 591
            A       R    +K P+   D  PP P  +              +V  V+ P      
Sbjct: 533 SA-------RSSRVIKTPRRFMDEDPPKPPKV--------------EVSPVLRPPITTS- 570

Query: 592 LSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFA 651
             P PQ      S         T   L EKR   L+E           T R  S + +  
Sbjct: 571 -PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP----------TFRWTSLTRELP 619

Query: 652 AGQGAERDVPDPQEGVGMETCPPQTTARDSQ----------GRGRAHTGMARSEDSVVLL 701
               A    P P         PP   A  S+              AH  +  S  +   L
Sbjct: 620 PPPPAPPPPPAPS--------PPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPL 671

Query: 702 GCQDSPGLRAARPTSPPQDHRPTCP---GVGTKDALDLPGGSPVRES--------HG--- 747
           G  ++P      P  PP D  P  P    VG  + L LP  +PV  +        HG   
Sbjct: 672 GAPEAP-----EPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726

Query: 748 LAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQSPSAERRG 807
           L+ G   + +L  L  L   Q +LLP  LP    P    L P    P    Q P  E+  
Sbjct: 727 LSNGPQTQAQL--LQPLQALQTQLLPQALP----PPQPQLQP----PPSPQQMPPLEKAR 776

Query: 808 LNLAPSPANKAKKQPLFGSLSPAE 831
           +    S      ++ +F  L  A+
Sbjct: 777 IAGVGSLPLSGVEEKMFSLLKRAK 800



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 128/536 (23%), Positives = 192/536 (35%), Gaps = 95/536 (17%)

Query: 278 PLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPD---DSCNPRSVYENFR 334
           PL PPPPP    PP+ S     P P  A  E      Q ++PP     +C+ +       
Sbjct: 427 PLCPPPPPPVSPPPLPS-----PPPPPAQEE------QEESPPPVVPATCSRKRGRPPLT 475

Query: 335 LWQHYKPLARRHLPQ--SPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSN 392
             Q  +  A R  P+  SP T   S              P  T      R       ++ 
Sbjct: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535

Query: 393 FDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPAT--PRLEPRGPPAPEVVKQP 450
             R+I  +   +F++ +  +  +++ S  ++ P    PP    P   P  P AP     P
Sbjct: 536 SSRVI--KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593

Query: 451 VYLPSKAGP---------KAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRP- 500
           V LP K             + T  LPPP P  P      PPP P          PPP P 
Sbjct: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPP------PPPAPS---------PPPAPA 638

Query: 501 ---QRPAETKVPEEIPPEVVQEYVDIMEELL-GPSLGATGEPEKQREEGKVKQPQEEDWT 556
              +RP   + P+  P E    ++ I E +L  P LGA   PE +        P ++   
Sbjct: 639 TSSRRPLLLRAPQFTPSEA---HLKIYESVLTPPPLGAPEAPEPE------PPPADDSPA 689

Query: 557 PPDPGLLSYIDKLCSQK---DFVTKVEAVIH----------PQFLEELLSPDPQMDFLAL 603
            P+P  +   + L   +      T V+A +           PQ   +LL P   +    L
Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749

Query: 604 SQDLEQEEGLTLAQLVEKRLPPLKEKQHS--RAAPSRGTARLDSSSSKFAAGQGAERDVP 661
            Q L   +         +++PPL++ + +   + P  G      S  K A  Q  + D  
Sbjct: 750 PQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQ 809

Query: 662 DPQEGVGMETCPPQTTARDSQGRGR--AHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQ 719
             Q+        P     +  G  +  +  G  RSED  V     ++   R + P SP Q
Sbjct: 810 QQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESV-----EAKRERPSGPESPVQ 864

Query: 720 DH------RPTCPGVGTKDAL---DLP--GGSPVRESHGLA----QGSSEEEELPS 760
                   R     +G   A+   D+P     P+R+   LA      +SE E +PS
Sbjct: 865 GPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPS 920



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 36/122 (29%), Positives = 44/122 (36%), Gaps = 33/122 (27%)

Query: 426  QCLPPPATPRLEPRGPPAPEV-----VKQPVY--------------LPSKAGPKAQTACL 466
            Q L PP  P      PPAP       +K P Y              LPS   P + T  +
Sbjct: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI 1898

Query: 467  P----------PPRPQRPVTKARRPPP----QPHRRAETKARLPPPRPQRPAETKVPEEI 512
            P          P R +RP   A RPPP     P  +   + R+PPP     A T    E+
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958

Query: 513  PP 514
             P
Sbjct: 1959 AP 1960



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 53/208 (25%), Positives = 69/208 (33%), Gaps = 56/208 (26%)

Query: 117  SAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPL 176
            S  P    +NG+ P    G+TA+P      F  LP                 GAP    L
Sbjct: 2135 SLPPAPPLANGSQP--SQGLTASPADPTRTFAWLP-----------------GAPGVRVL 2175

Query: 177  VLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTE----VGPVKAAQAQTLVLTQAPLVWQ 232
             L   P  P          +  G   VFV+M  E      PVK       +   AP  W 
Sbjct: 2176 SLGPAPEPPKPATSKIILVNKLG--QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW- 2232

Query: 233  APGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPI 292
                       PP  LL   PVV                    G+  P PPPP   L  +
Sbjct: 2233 ---------TLPPGPLLGVLPVV--------------------GVVRPAPPPPPPPLTLV 2263

Query: 293  VSQGNAGPWPQGAHGESSLASSQAKAPP 320
            +S G A P P+ A     +++   ++PP
Sbjct: 2264 LSSGPASP-PRQAIRVKRVSTFSGRSPP 2290



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 53/215 (24%), Positives = 76/215 (35%), Gaps = 49/215 (22%)

Query: 423  KGPQCLPPPATPRLEP-RGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRP 481
            + P+  P P  PR     G P  EVV  P       GP+ Q + L     +R V +  RP
Sbjct: 1034 ESPEASPGPPGPRRGAGAGGPREEVVAHP-------GPEEQDSLLQRKSARRCVKQ--RP 1084

Query: 482  ---------------PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEE 526
                           PP P RR   +  LP P P+  +  + P   P   ++    + ++
Sbjct: 1085 SYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKD 1144

Query: 527  LLGPS------LGATGEPEKQREEGKVKQPQEED------W-------TPPDPGLLSYID 567
             L P        G TG+ +      +V+   +ED      W           PG    + 
Sbjct: 1145 ALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVC 1204

Query: 568  KLCSQKDFVTKVEAVI-----HPQFLEELLSPDPQ 597
             LC+ K     V   +     HP  LEE   P PQ
Sbjct: 1205 LLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQ 1239



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 435  RLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRP---QRPVTKARRPPPQP 485
            ++   G P P  VKQP  LP    P A T+   PP P     PV    RP P P
Sbjct: 2203 KMAGEGEPVPPPVKQPP-LPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPP 2255


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 54/241 (22%), Positives = 96/241 (39%), Gaps = 46/241 (19%)

Query: 342  LARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEM 401
            ++++ +PQ P    +   +I V       K  +  EE ++ A       S+ +  +   +
Sbjct: 9209 VSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFA-------SHTEEEVSVTV 9261

Query: 402  AEKFLEFEAEEEMQIQKSQWMKGP-------------QCLPPPATPRLEPRGPPAPEVVK 448
             E   E   EE++ +  S+ ++ P             +  P P   ++EP  P  PEV K
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK 9321

Query: 449  QPVYLPSKAGPKAQTACLPPPR----PQRPVTKARRPPPQPHRRAETKARLPPPRPQRPA 504
            +PV    K  P  +     PP+    P++PV + + P P   ++    A++P  +     
Sbjct: 9322 KPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVT 9381

Query: 505  ETKVP-----EEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
            E K+      EE PP  V E                  P+K+  E +   P++E+  PP 
Sbjct: 9382 EEKITIVTQREESPPPAVPEI-----------------PKKKVPEERKPVPRKEEEVPPP 9424

Query: 560  P 560
            P
Sbjct: 9425 P 9425



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 62/231 (26%), Positives = 96/231 (41%), Gaps = 50/231 (21%)

Query: 377   EEGLWRAMREW----QHTSNFDRMIFYEMAEKFLE-FEAEEEMQIQKSQWM-KGPQC--- 427
             EEG +  + E+    QH    +  +  E   + +E FEAEE    +K +   KGP+    
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRV--EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448

Query: 428   -LPP--PATPRLEPRGPPA--PEV-----VKQPVYLPS--KAGPKAQTACLPP----PRP 471
              +PP  P T  +  + PPA  PEV     V++ V +P   +  P      LPP    P  
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK 10508

Query: 472   QRPVTKARRPPPQPHRRAET------KARLPPPRPQRPA---------------ETKVPE 510
             + PV  A++P   P +  E       + ++P P P++P                E KVPE
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPE 10568

Query: 511   EIPPEVVQEYVDIME--ELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
              IPP+      ++ E  + + P       P K+ E   VK P+      P+
Sbjct: 10569 AIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPE 10619



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 64/290 (22%), Positives = 120/290 (41%), Gaps = 54/290 (18%)

Query: 367  LARRKPTMTLEEGLWRAMRE--WQHTSNFDRMIF--YEMAEKFLEFEAEEEMQIQKSQWM 422
            +  ++   TLEE      RE  ++    +D   F  YE  E++ ++E  EE + ++ +  
Sbjct: 9723 MEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYE-- 9780

Query: 423  KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRP 481
            +  + +  P  P                  +P K            P P+ PV TK + P
Sbjct: 9781 EHEEYITEPEKP------------------IPVK------------PVPEEPVPTKPKAP 9810

Query: 482  PPQPHRRA--ETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDI------MEELLGPSLG 533
            P +  ++A  E K  +P P+  +P   KVPEE P +V +E + I       E++  P+  
Sbjct: 9811 PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE-PKKVFEEKIRISITKREKEQVTEPAAK 9869

Query: 534  ATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLS 593
               +P++   E KV  P++E      P  +  + K    ++   + E V H   +EE L 
Sbjct: 9870 VPMKPKRVVAEEKVPVPRKE---VAPPVRVPEVPKELEPEEVAFEEEVVTH---VEEYLV 9923

Query: 594  PDPQMDFLALSQDLEQEEGLTLAQLVEKRLP--PLKEKQHSRAAPSRGTA 641
             + +       + + +EE + +  +    +P  P+ E++     P +  A
Sbjct: 9924 EEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEA 9973



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 44/152 (28%), Positives = 63/152 (41%), Gaps = 30/152 (19%)

Query: 423   KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPP 482
             K P+ +PP      +P  PP PEV + P     +  P+ +    PP +P+  VT  + P 
Sbjct: 10565 KVPEAIPP------KPESPP-PEVPEAP----KEVVPEKKVPAAPPKKPE--VTPVKVPE 10611

Query: 483   PQPHRRAETKARLPPPR---------PQRPA----ETKVPEEIPPEVVQEYVDIMEELLG 529
                    E K  +PPP+         P+ P     E KVPE IPP+      ++ EE   
Sbjct: 10612 APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE--- 10668

Query: 530   PSLGATGEPEKQ-REEGKVKQPQEEDWTPPDP 560
             P   A  EP  +  EE +   P +    P  P
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP 10700



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 17/151 (11%)

Query: 411   EEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPP 469
             EE  +I   + +   +  P P     EP  PP P V ++P   +P K  P  +    PPP
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP-PAVPEEPKKIIPEKKVPVIKKPEAPPP 10863

Query: 470   RPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEE------IPPEVVQEYVDI 523
             +   P     +P  +P          PPP P  P +  V E+      IP + V E   +
Sbjct: 10864 KEPEPEKVIEKPKLKPR---------PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914

Query: 524   MEELLGPSLGATGEPEKQREEGKVKQPQEED 554
              E++    L   G  +K R+    ++P+ ++
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 16/200 (8%)

Query: 432   ATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAET 491
             A P   P  P  PE  K PV +P K  P        P  P++PV + + P P P +    
Sbjct: 9973  APPAKVPEVPKKPEE-KVPVLIPKKEKPPPAKV---PEVPKKPVPEEKVPVPVPKKVEAP 10028

Query: 492   KARLPPPRPQRPAETKVPEEIPPEV---VQEYVDIMEELLGPSLGATGEPEKQREEGKVK 548
              A++P    +   E KVP   P +V     +  ++ ++L+      T  P+K  E    K
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV-EAPPPK 10087

Query: 549   QPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLE 608
              P++ +   P P  L   +++  +++ V + E +  P+  EE + P+ +       + L 
Sbjct: 10088 VPKKRE-PVPVPVALPQEEEVLFEEEIVPEEEVL--PE--EEEVLPEEEEVLPEEEEVLP 10142

Query: 609   QEEGLTLAQLVEKRLPPLKE 628
             +EE +      E+ +PP +E
Sbjct: 10143 EEEEIPPE---EEEVPPEEE 10159



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 31/156 (19%)

Query: 428   LPPPATPRLEP-RGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRP--VTKARRPPPQ 484
             +PPP  P + P + P  P+       +P    PK ++   PP  P+ P  V   ++ P  
Sbjct: 10540 VPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP--PPEVPEAPKEVVPEKKVPAA 10597

Query: 485   PHRRAET----------------KARLPPPRPQRPAETKVPE----EIPPEVVQEYVDIM 524
             P ++ E                 K  +PPP+      TKVPE     +P + V E +   
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK 10657

Query: 525   EELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDP 560
              E   P      E  ++ EE  +++P  E    P+P
Sbjct: 10658 PESPPP------EVFEEPEEVALEEPPAEVVEEPEP 10687



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 112/495 (22%), Positives = 178/495 (35%), Gaps = 123/495 (24%)

Query: 155  PAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPV 214
            P P P   P      APP  P V    P  P+  E+            V V  + E  P 
Sbjct: 9330 PVPVPKKEP-----AAPPKVPEV----PKKPVPEEK----------IPVPVAKKKEAPPA 9370

Query: 215  KAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWS 274
            K  + Q  V+T+  +       +      PPP        VP +  + V   +       
Sbjct: 9371 KVPEVQKGVVTEEKIT-----IVTQREESPPP-------AVPEIPKKKVPEERKPVPRKE 9418

Query: 275  QGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFR 334
            + +P PPP  PA    P+  +  A P P              KAPP     PR+      
Sbjct: 9419 EEVP-PPPKVPALPKKPVPEEKVAVPVPVAK-----------KAPP-----PRAEVSKKT 9461

Query: 335  LWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFD 394
            + +  + +A   L           F +P    + R + +         A  EW ++   +
Sbjct: 9462 VVEEKRFVAEEKLS----------FAVPQRVEVTRHEVS---------AEEEWSYSEEEE 9502

Query: 395  RMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPA-----TPRLEPRGPPAPEVVKQ 449
             +      E+  E E EEE ++ + + M+ P+           + R+E       E  ++
Sbjct: 9503 GVSISVYREE--EREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEK 9560

Query: 450  PVYLPSKAGPKAQTACLPPPR-----PQRPVTKARRPPPQPHRRAETKARLPPPR-PQRP 503
             + L  K   K +    PPP      P++ V + + P P P      K ++PPP+ P+ P
Sbjct: 9561 KIVLKPKIPAKIEE---PPPAKVPEAPKKIVPEKKVPAPVPK-----KEKVPPPKVPEEP 9612

Query: 504  AETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLL 563
             +    +++PP+V++     MEE L         P K  E   ++  QEE          
Sbjct: 9613 KKPVPEKKVPPKVIK-----MEEPL---------PAKVTER-HMQITQEEKVLVA----- 9652

Query: 564  SYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRL 623
                        VTK EA    +  EE     P+   L L    E+E     A++ E R 
Sbjct: 9653 ------------VTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPP---AKVTEFRK 9697

Query: 624  PPLKEKQHSRAAPSR 638
              +KE++ S  AP R
Sbjct: 9698 RVVKEEKVSIEAPKR 9712



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 51/199 (25%), Positives = 80/199 (40%), Gaps = 35/199 (17%)

Query: 423   KGPQCLPPPATPRLEPRGPPAPEVVKQP------------VYLPSKAGPKAQTACLPPPR 470
             K P+ +PP      +P  PP PEV ++P            V  P  A P   T  +PP +
Sbjct: 10649 KVPEAIPP------KPESPP-PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT--VPPKK 10699

Query: 471   P----QRPVTKARRPPPQPHRRAETKARLPPPR------PQRPAE--TKVPEEIPPEVVQ 518
             P    + P   A++P   P +  E    + P +      P++P     KVP E+P EVV 
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVP-EVPKEVVP 10758

Query: 519   E-YVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVT 577
             E  V + ++   P       P+K   E K   P  E    P P +    +++  +++   
Sbjct: 10759 EKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP 10818

Query: 578   KVEAVIHPQFLEELLSPDP 596
             + E  +     EE   P P
Sbjct: 10819 EEEKPVPVAEEEEPEVPPP 10837



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 73/328 (22%), Positives = 118/328 (35%), Gaps = 63/328 (19%)

Query: 282   PPPPAAQLP---------PIVSQGNAGPWPQGAHGESSLASSQAKA--PPDDSCNPRSVY 330
             PPP   + P         P++ +  A P P+    E  +   + K   PP     P+   
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPP-PKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893

Query: 331   ENFRLWQHYKPLARRHLP---QSPDTEALSCFLIP-----VLRSLARRKPTMTLEEGLWR 382
             +  +++Q  K + ++ +P   Q P+   L+   +P     V + L  RKP    E  L  
Sbjct: 10894 KE-KIFQ-LKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKS 10951

Query: 383   AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPP 442
              +R+                      E E +++ +K + +K P    PP    +E     
Sbjct: 10952 VLRKRPE-------------------EEEPKVEPKKLEKVKKPAVPEPPPPKPVEE--VE 10990

Query: 443   APEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQR 502
              P V K+   +P           +P P P+          P+P   AE K   PPP    
Sbjct: 10991 VPTVTKRERKIPEPTKVPEIKPAIPLPAPE----------PKPKPEAEVKTIKPPPVEPE 11040

Query: 503   PAETKVPEEIPPEVVQEYVDI---MEELLGPSLGATGEPEKQ----REEGKVKQPQEEDW 555
             P     P  +P  VV +  +     EE   P     G P+K       E +  +P     
Sbjct: 11041 PTPIAAPVTVP--VVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGE 11098

Query: 556   TPPDPGLLSYIDKLCSQKDFVTKVEAVI 583
              PPD    +Y  K    K FV +++ +I
Sbjct: 11099 KPPDEAPFTYQLKAVPLK-FVKEIKDII 11125



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 25/165 (15%)

Query: 394   DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPP-APEVVKQPVY 452
             ++ I     E+ L  E  EE + +     + P+   PP+   +E   PP  PEV+K    
Sbjct: 10221 EKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE--EPPSIEEVEEVAPPRVPEVIK---- 10274

Query: 453   LPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEI 512
                KA P+A T          PV K    PP    +   + ++P P  ++ A      E+
Sbjct: 10275 ---KAVPEAPT----------PVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEV 10321

Query: 513   PPEVVQEYVDI-MEELLGPSLGATGEPEKQ----REEGKVKQPQE 552
             P +V ++ V +  +E + P+ G T   EK     R+E  VK+  E
Sbjct: 10322 PKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLE 10366



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 60/236 (25%), Positives = 103/236 (43%), Gaps = 21/236 (8%)

Query: 409   EAEEEMQIQKSQWMKGPQCLP--PPATPRLEPRGPPAPEVVKQPVYLPSKA-GPKAQTAC 465
             E EEE   ++ +++   + +P  P   P + PR P   E  K+PV +P K   P A+   
Sbjct: 9924  EEEEEYIHEEEEFITEEEVVPVIPVKVPEV-PRKPVPEE--KKPVPVPKKKEAPPAKVPE 9980

Query: 466   LPP-PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPP----EVVQEY 520
             +P  P  + PV   ++  P P +  E   + P P  + P       E PP    EV ++ 
Sbjct: 9981  VPKKPEEKVPVLIPKKEKPPPAKVPEVPKK-PVPEEKVPVPVPKKVEAPPAKVPEVPKKP 10039

Query: 521   VDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVE 580
             V   +  +         P K  E  K   P+E+  TP    + +   K+  +++ V    
Sbjct: 10040 VPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPV 10099

Query: 581   AVIHPQFLEELLSPD--PQMDFLALSQDL--EQEEGLTLAQLV---EKRLPPLKEK 629
             A+  PQ  E L   +  P+ + L   +++  E+EE L   + V   E+ +PP +E+
Sbjct: 10100 AL--PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEE 10153



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 36/129 (27%)

Query: 428  LPPPATPRLEPRGPPA-----PEVVKQPVYLPSK----------------------AGPK 460
            +PPP  P  EP+ P       P+V+K    LP+K                      A PK
Sbjct: 9603 VPPPKVPE-EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPK 9661

Query: 461  AQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIP---PEVV 517
            A+     P  P+R V + +    +P R  E  A++   R +   E KV  E P   P+ +
Sbjct: 9662 ARV----PEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPI 9717

Query: 518  QEYVDIMEE 526
            +E V IMEE
Sbjct: 9718 KE-VTIMEE 9725



 Score = 33.5 bits (75), Expect = 0.89
 Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 15/90 (16%)

Query: 410 AEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPP 469
           A  EM I  +   + P   PP   P+ + R P  P +             KAQ A    P
Sbjct: 235 ATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAA-----------KAQLARQQSP 283

Query: 470 RPQR----PVTKARRPPPQPHRRAETKARL 495
            P R    PV   R P P P R     AR+
Sbjct: 284 SPIRHSPSPVRHVRAPTPSPVRSVSPAARI 313



 Score = 33.5 bits (75), Expect = 0.89
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 27/138 (19%)

Query: 398  FYEMAEKFLEFEAE--------EEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQ 449
            +YE  E + E E E        E +Q+QK  + +  +   P   P  E + PP P+V+K+
Sbjct: 9126 YYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVP--EKKAPPPPKVIKK 9183

Query: 450  PVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQR-PAETKV 508
            PV                  + ++   +      Q  +  E   ++ P +P R P + +V
Sbjct: 9184 PVI----------------EKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEV 9227

Query: 509  PEEIPPEVVQEYVDIMEE 526
             E   P V  + + I EE
Sbjct: 9228 IEVKVPAVHTKKMVISEE 9245


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 167/769 (21%), Positives = 260/769 (33%), Gaps = 137/769 (17%)

Query: 118  AQPEGMASNGAY-------PVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGA 170
            AQP G+    A        PV  PG T  P   L             GPA  P   T   
Sbjct: 333  AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-------------GPAKPPAQQTGSE 379

Query: 171  PPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLV 230
             P      S  P    + +  G   + A           +VG  K    Q  + + A   
Sbjct: 380  KPS-----SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA--- 431

Query: 231  WQAPGALCGGVVCPPPLLLAAAPVVP-VMAAQVVGGTQ--------ACEGGWSQGLPLPP 281
             +APG     V  P P  + A    P   +AQ  G T+        A       G   PP
Sbjct: 432  -KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490

Query: 282  PPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKP 341
            P  P +  PP    G+  P PQ   G +  +  Q  +    S  P S   + +     KP
Sbjct: 491  PQQPGSAKPPSQQPGSTKPPPQ-QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549

Query: 342  LARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGL------WRAMREWQHTSNFDR 395
             A++       T +      P +   A++ P+  L + +         +      +NF+ 
Sbjct: 550  SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609

Query: 396  MIFYEMAEKFLEFEAEEEMQIQKSQWM---------KGPQCLPPPATPRLEPRGPPAPEV 446
                +     L          +  +W+          G    P P++P  +P+   AP  
Sbjct: 610  CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVT 667

Query: 447  VKQPVYLPSKAGPK-AQTACLPPPRPQRPVTKA---RRPPP---QP--HRRAETKARLPP 497
                V   SK+ P+  QT+      P++ ++KA   ++PPP   QP  H     KA+ PP
Sbjct: 668  TTSAV---SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 498  -----PRPQRPAETKVPEEIPPEVVQEYVDIMEELLGP------SLGATGEPEKQREEGK 546
                  +P  P E  VP E     V +      +++ P      S  AT +P+      K
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD--IPSSK 782

Query: 547  VKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQD 606
            V+   EE  TPP        D     + F    E V      +    P P  D   +S  
Sbjct: 783  VQSQAEEKTTPP-----LKTDSAKPSQSFPPTGEKV---SPFDSKAIPRPASDSKIIS-- 832

Query: 607  LEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVPDPQEG 666
                 G +     +K++ P+++K+  + A ++ + + D+        +G+    P P+  
Sbjct: 833  ---HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP----KGSPTP-PGPRPT 884

Query: 667  VGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQDHRPTCP 726
             G     PQ + +  +   R          S+ L    D+P    ++PT+P +       
Sbjct: 885  AGQTVPTPQQSPKPQEQSRRF---------SLNLGSITDAP---KSQPTTPQETVTGKLF 932

Query: 727  GVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGL 786
            G G                   A   S+   L S A   G   +  P   P    PA   
Sbjct: 933  GFG-------------------ASIFSQASNLISTAGQPGPHSQSGP-GAPMKQAPAPSQ 972

Query: 787  LSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSP-AEKTP 834
                +  P+ T Q+P A  + +     P  K  K P    L P AE+ P
Sbjct: 973  PPTSQGPPKSTGQAPPAPAKSI-----PVKKETKAPAAEKLEPKAEQAP 1016



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 119/523 (22%), Positives = 171/523 (32%), Gaps = 100/523 (19%)

Query: 423 KGPQCLPPPATPRLEPRGPP--------------APEVVKQPVYLP-------SKAGPKA 461
           K P   P PA P  +  G P              AP   K PV  P        +AGP  
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK 458

Query: 462 QTA-----CLPP--------PRPQRPVTKARRPPPQPHRRAETKARLP------------ 496
            +A       PP        P PQ+P     +PPPQ    A+  ++ P            
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516

Query: 497 -PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQP---QE 552
             P PQ+P  TK P + P                PS   + +P  Q   GK  QP     
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQ--QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574

Query: 553 EDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEEL---------LSPDPQM----D 599
               PP  GL   I  LC+  + +  V    +     E           +P+P +    +
Sbjct: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634

Query: 600 FLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSS--------SKFA 651
           +L L+  +++  G  LA +     P LK       AP   T+ +  SS         K A
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLK------TAPVTTTSAVSKSSPQPQQTSPKKDA 688

Query: 652 AGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRA 711
           A +      P+P++       PP        G   A        DS+        P + +
Sbjct: 689 APKQDLSKAPEPKKP------PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS 742

Query: 712 ARPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGL----AQGSSEEEELPSL-AFLLG 766
            +  +P  D +P  P +  K   DL   S       +     Q  +EE+  P L      
Sbjct: 743 EQDKAPVADDKPKQPKM-VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAK 801

Query: 767 SQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANK--AKKQPLF 824
                 P     SP  +  +  P       +H  PS+E +G         K   KK    
Sbjct: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861

Query: 825 GSLSPAEKTPHRG----PGLRVSGEQSLTWGLGGPS-QSQKRK 862
            S  P  K   +G    PG R +  Q++      P  Q Q R+
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 15/133 (11%)

Query: 429 PPPATPRLEPRG-----PPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRP-P 482
           P PA P  +P G        P  VK PV  P    P AQ   L P +P    T + +P  
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEKPSS 383

Query: 483 PQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEE--LLGPSL--GATGEP 538
            QP  +A  +   PP   + PA+   P + P + V     + ++  L  P+   G T  P
Sbjct: 384 EQPGPKALAQ---PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 539 EKQREEGKVKQPQ 551
            +Q   GK+   Q
Sbjct: 441 VQQPGPGKIPAQQ 453



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 89/399 (22%), Positives = 136/399 (34%), Gaps = 95/399 (23%)

Query: 471 PQRPVTKARRPPPQPHRRAETKARLPP------PRPQRPAETKVPEEIPPEVVQEYVDIM 524
           P+  V  A    P  HR+ E  +  PP      P P RPA+  + +    +  +      
Sbjct: 67  PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE---- 122

Query: 525 EELLGPSLGATGEPE-KQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVI 583
           ++L G S       E K R + K     EE  +   PG LS ++ L +    V K     
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLK-----EEHKSSMMPGFLSEVNALSAVSSVVNKFNPF- 176

Query: 584 HPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRL--------PPLKEKQHSRAA 635
                 +L+S            +  QEE     ++V+K          PPL++ Q  +  
Sbjct: 177 ------DLIS----------DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ-QPPKPI 219

Query: 636 PSRGTARLDSSSSKFAAGQGAERDVPDPQEGV--GMETCPPQTTARDSQGRGRAHTGMAR 693
           P +               QG  RD P  Q+G    + +  P+       G G+   G  +
Sbjct: 220 PKQ---------------QGPGRD-PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263

Query: 694 SEDSVVLLGCQDSPGLRAARPTSPPQDHRPTCP-GVGTKDALDLPGGSPVRE---SHGLA 749
           +  +       D   L   R  S PQ  +     G   K +L  P   P+++       A
Sbjct: 264 TPQT-------DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316

Query: 750 QGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQSPSAERRGLN 809
           Q    E+  P  A               + P   SGL  P    P GT + P        
Sbjct: 317 QQPGHEKSQPGPA---------------KPPAQPSGLTKPLAQQP-GTVKPP-------- 352

Query: 810 LAPSPANKAKKQPLFGSLSPAEKTPHRGPGLRVSGEQSL 848
           + P    K   QPL  +  PA++T    P     G ++L
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 24/116 (20%)

Query: 455  SKAGPKAQTACLP----PPRPQRPVTKARRPPPQPHR----RAETKA----RLPPPRPQR 502
            S++GP A     P    PP  Q P     + PP P +    + ETKA    +L P   Q 
Sbjct: 956  SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015

Query: 503  PAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV-KQPQEEDWTP 557
            P   +   E  P  +++           S   T EP+K     K+ K P+ E   P
Sbjct: 1016 PTVKRTETEKKPPPIKD-----------SKSLTAEPQKAVLPTKLEKSPKPESTCP 1060


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 167/769 (21%), Positives = 260/769 (33%), Gaps = 137/769 (17%)

Query: 118  AQPEGMASNGAY-------PVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGA 170
            AQP G+    A        PV  PG T  P   L             GPA  P   T   
Sbjct: 333  AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-------------GPAKPPAQQTGSE 379

Query: 171  PPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLV 230
             P      S  P    + +  G   + A           +VG  K    Q  + + A   
Sbjct: 380  KPS-----SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA--- 431

Query: 231  WQAPGALCGGVVCPPPLLLAAAPVVP-VMAAQVVGGTQ--------ACEGGWSQGLPLPP 281
             +APG     V  P P  + A    P   +AQ  G T+        A       G   PP
Sbjct: 432  -KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490

Query: 282  PPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKP 341
            P  P +  PP    G+  P PQ   G +  +  Q  +    S  P S   + +     KP
Sbjct: 491  PQQPGSAKPPSQQPGSTKPPPQ-QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549

Query: 342  LARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGL------WRAMREWQHTSNFDR 395
             A++       T +      P +   A++ P+  L + +         +      +NF+ 
Sbjct: 550  SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609

Query: 396  MIFYEMAEKFLEFEAEEEMQIQKSQWM---------KGPQCLPPPATPRLEPRGPPAPEV 446
                +     L          +  +W+          G    P P++P  +P+   AP  
Sbjct: 610  CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVT 667

Query: 447  VKQPVYLPSKAGPK-AQTACLPPPRPQRPVTKA---RRPPP---QP--HRRAETKARLPP 497
                V   SK+ P+  QT+      P++ ++KA   ++PPP   QP  H     KA+ PP
Sbjct: 668  TTSAV---SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 498  -----PRPQRPAETKVPEEIPPEVVQEYVDIMEELLGP------SLGATGEPEKQREEGK 546
                  +P  P E  VP E     V +      +++ P      S  AT +P+      K
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD--IPSSK 782

Query: 547  VKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQD 606
            V+   EE  TPP        D     + F    E V      +    P P  D   +S  
Sbjct: 783  VQSQAEEKTTPP-----LKTDSAKPSQSFPPTGEKV---SPFDSKAIPRPASDSKIIS-- 832

Query: 607  LEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVPDPQEG 666
                 G +     +K++ P+++K+  + A ++ + + D+        +G+    P P+  
Sbjct: 833  ---HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP----KGSPTP-PGPRPT 884

Query: 667  VGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQDHRPTCP 726
             G     PQ + +  +   R          S+ L    D+P    ++PT+P +       
Sbjct: 885  AGQTVPTPQQSPKPQEQSRRF---------SLNLGSITDAP---KSQPTTPQETVTGKLF 932

Query: 727  GVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGL 786
            G G                   A   S+   L S A   G   +  P   P    PA   
Sbjct: 933  GFG-------------------ASIFSQASNLISTAGQPGPHSQSGP-GAPMKQAPAPSQ 972

Query: 787  LSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSP-AEKTP 834
                +  P+ T Q+P A  + +     P  K  K P    L P AE+ P
Sbjct: 973  PPTSQGPPKSTGQAPPAPAKSI-----PVKKETKAPAAEKLEPKAEQAP 1016



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 119/523 (22%), Positives = 171/523 (32%), Gaps = 100/523 (19%)

Query: 423 KGPQCLPPPATPRLEPRGPP--------------APEVVKQPVYLP-------SKAGPKA 461
           K P   P PA P  +  G P              AP   K PV  P        +AGP  
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK 458

Query: 462 QTA-----CLPP--------PRPQRPVTKARRPPPQPHRRAETKARLP------------ 496
            +A       PP        P PQ+P     +PPPQ    A+  ++ P            
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516

Query: 497 -PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQP---QE 552
             P PQ+P  TK P + P                PS   + +P  Q   GK  QP     
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQ--QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574

Query: 553 EDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEEL---------LSPDPQM----D 599
               PP  GL   I  LC+  + +  V    +     E           +P+P +    +
Sbjct: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634

Query: 600 FLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSS--------SKFA 651
           +L L+  +++  G  LA +     P LK       AP   T+ +  SS         K A
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLK------TAPVTTTSAVSKSSPQPQQTSPKKDA 688

Query: 652 AGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRA 711
           A +      P+P++       PP        G   A        DS+        P + +
Sbjct: 689 APKQDLSKAPEPKKP------PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS 742

Query: 712 ARPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGL----AQGSSEEEELPSL-AFLLG 766
            +  +P  D +P  P +  K   DL   S       +     Q  +EE+  P L      
Sbjct: 743 EQDKAPVADDKPKQPKM-VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAK 801

Query: 767 SQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANK--AKKQPLF 824
                 P     SP  +  +  P       +H  PS+E +G         K   KK    
Sbjct: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861

Query: 825 GSLSPAEKTPHRG----PGLRVSGEQSLTWGLGGPS-QSQKRK 862
            S  P  K   +G    PG R +  Q++      P  Q Q R+
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 15/133 (11%)

Query: 429 PPPATPRLEPRG-----PPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRP-P 482
           P PA P  +P G        P  VK PV  P    P AQ   L P +P    T + +P  
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEKPSS 383

Query: 483 PQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEE--LLGPSL--GATGEP 538
            QP  +A  +   PP   + PA+   P + P + V     + ++  L  P+   G T  P
Sbjct: 384 EQPGPKALAQ---PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 539 EKQREEGKVKQPQ 551
            +Q   GK+   Q
Sbjct: 441 VQQPGPGKIPAQQ 453



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 89/399 (22%), Positives = 136/399 (34%), Gaps = 95/399 (23%)

Query: 471 PQRPVTKARRPPPQPHRRAETKARLPP------PRPQRPAETKVPEEIPPEVVQEYVDIM 524
           P+  V  A    P  HR+ E  +  PP      P P RPA+  + +    +  +      
Sbjct: 67  PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE---- 122

Query: 525 EELLGPSLGATGEPE-KQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVI 583
           ++L G S       E K R + K     EE  +   PG LS ++ L +    V K     
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLK-----EEHKSSMMPGFLSEVNALSAVSSVVNKFNPF- 176

Query: 584 HPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRL--------PPLKEKQHSRAA 635
                 +L+S            +  QEE     ++V+K          PPL++ Q  +  
Sbjct: 177 ------DLIS----------DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ-QPPKPI 219

Query: 636 PSRGTARLDSSSSKFAAGQGAERDVPDPQEGV--GMETCPPQTTARDSQGRGRAHTGMAR 693
           P +               QG  RD P  Q+G    + +  P+       G G+   G  +
Sbjct: 220 PKQ---------------QGPGRD-PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263

Query: 694 SEDSVVLLGCQDSPGLRAARPTSPPQDHRPTCP-GVGTKDALDLPGGSPVRE---SHGLA 749
           +  +       D   L   R  S PQ  +     G   K +L  P   P+++       A
Sbjct: 264 TPQT-------DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316

Query: 750 QGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQSPSAERRGLN 809
           Q    E+  P  A               + P   SGL  P    P GT + P        
Sbjct: 317 QQPGHEKSQPGPA---------------KPPAQPSGLTKPLAQQP-GTVKPP-------- 352

Query: 810 LAPSPANKAKKQPLFGSLSPAEKTPHRGPGLRVSGEQSL 848
           + P    K   QPL  +  PA++T    P     G ++L
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 24/116 (20%)

Query: 455  SKAGPKAQTACLP----PPRPQRPVTKARRPPPQPHR----RAETKA----RLPPPRPQR 502
            S++GP A     P    PP  Q P     + PP P +    + ETKA    +L P   Q 
Sbjct: 956  SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015

Query: 503  PAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV-KQPQEEDWTP 557
            P   +   E  P  +++           S   T EP+K     K+ K P+ E   P
Sbjct: 1016 PTVKRTETEKKPPPIKD-----------SKSLTAEPQKAVLPTKLEKSPKPESTCP 1060


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 160/710 (22%), Positives = 240/710 (33%), Gaps = 125/710 (17%)

Query: 172  PGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPV-KAAQAQTLVLTQAPLV 230
            P G   ++     P   ++D   P  +  +       T++    K   A T+V  QA   
Sbjct: 574  PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 633

Query: 231  WQAPGALCGGVVCPPPLL----LAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPA 286
               P      V+ PP  L    L++AP  PV AA +V  +Q  E    +GL LP      
Sbjct: 634  LTLPQ---DSVMTPPLPLQDTELSSAPK-PVAAATLV--SQQAE----EGLTLPQDSAMT 683

Query: 287  AQLPPIVSQGNAGPWPQGAHGESSLASSQAKA----PPDDSCNPRSVYENFRLWQHYKPL 342
              LP   +  ++ P P  A   ++L S QA+     P D +  P    ++  L    KP+
Sbjct: 684  PPLPLQDTDLSSAPKPVAA---ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 740

Query: 343  ARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMA 402
            A   L      E L+      L   +   P + L++            S+  + +    A
Sbjct: 741  AAATLVSQQAEEGLT------LPQDSAMTPPLPLQD---------TDLSSAPKPV---AA 782

Query: 403  EKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKA 461
               +  +AEE + + +   M      PP      +    P P      V   ++ G    
Sbjct: 783  ATIVSQQAEEGLTLPQDSAMT-----PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP 837

Query: 462  QTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEE---IPPEVVQ 518
            Q + + PP P +    +  P P         A   P   Q      +P++    PP  +Q
Sbjct: 838  QDSAMTPPLPLQDTDLSSAPKPV--------AAATPVSQQAEEGLTLPQDSAMTPPLPLQ 889

Query: 519  EYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPP----DPGLLSYIDKLCSQKD 574
            +  D+      P   A   P  Q+ E  +  PQ+   T P    D G  S  + L     
Sbjct: 890  D-TDLSS---APKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP 945

Query: 575  FVTKVEAVIHP----------QFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLP 624
               + EA   P          Q + E L P P            +E+   L  + E    
Sbjct: 946  QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA----------PEEKNAALPTVPEPAAL 995

Query: 625  PLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTT-ARDSQG 683
               ++   + A   GT       +    G  A   +P+P  G G E     +   R++  
Sbjct: 996  DQVQQDDPQPAAEAGTPWAAQEDADSTLGMEA-LSLPEPASGAGEEIAEALSRPGREACL 1054

Query: 684  RGRAHTGMARSEDS----VVLLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGG 739
              RAHTG     DS     + +  Q   GL+        Q+H P     G ++  D P  
Sbjct: 1055 EARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA-----QEHGPRSALGGAREVPDAPPA 1109

Query: 740  -----------SPVRESHGLAQGSSEEEELPSLAFLLGSQHKL----------LPWWLPQ 778
                       SP RE  GL+  S+ E  LPS      S              L    P 
Sbjct: 1110 ACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPD 1169

Query: 779  SPVPASGLLSPEKWGPQG------THQSPSAERRGLNLAPSPANKAKKQP 822
            +P P S   S +     G       H+ PS    G  L   P N AK QP
Sbjct: 1170 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSV--LGTPLLQPPENLAKGQP 1217


>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 160/710 (22%), Positives = 240/710 (33%), Gaps = 125/710 (17%)

Query: 172  PGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPV-KAAQAQTLVLTQAPLV 230
            P G   ++     P   ++D   P  +  +       T++    K   A T+V  QA   
Sbjct: 574  PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 633

Query: 231  WQAPGALCGGVVCPPPLL----LAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPA 286
               P      V+ PP  L    L++AP  PV AA +V  +Q  E    +GL LP      
Sbjct: 634  LTLPQ---DSVMTPPLPLQDTELSSAPK-PVAAATLV--SQQAE----EGLTLPQDSAMT 683

Query: 287  AQLPPIVSQGNAGPWPQGAHGESSLASSQAKA----PPDDSCNPRSVYENFRLWQHYKPL 342
              LP   +  ++ P P  A   ++L S QA+     P D +  P    ++  L    KP+
Sbjct: 684  PPLPLQDTDLSSAPKPVAA---ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 740

Query: 343  ARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMA 402
            A   L      E L+      L   +   P + L++            S+  + +    A
Sbjct: 741  AAATLVSQQAEEGLT------LPQDSAMTPPLPLQD---------TDLSSAPKPV---AA 782

Query: 403  EKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKA 461
               +  +AEE + + +   M      PP      +    P P      V   ++ G    
Sbjct: 783  ATIVSQQAEEGLTLPQDSAMT-----PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP 837

Query: 462  QTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEE---IPPEVVQ 518
            Q + + PP P +    +  P P         A   P   Q      +P++    PP  +Q
Sbjct: 838  QDSAMTPPLPLQDTDLSSAPKPV--------AAATPVSQQAEEGLTLPQDSAMTPPLPLQ 889

Query: 519  EYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPP----DPGLLSYIDKLCSQKD 574
            +  D+      P   A   P  Q+ E  +  PQ+   T P    D G  S  + L     
Sbjct: 890  D-TDLSS---APKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP 945

Query: 575  FVTKVEAVIHP----------QFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLP 624
               + EA   P          Q + E L P P            +E+   L  + E    
Sbjct: 946  QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA----------PEEKNAALPTVPEPAAL 995

Query: 625  PLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTT-ARDSQG 683
               ++   + A   GT       +    G  A   +P+P  G G E     +   R++  
Sbjct: 996  DQVQQDDPQPAAEAGTPWAAQEDADSTLGMEA-LSLPEPASGAGEEIAEALSRPGREACL 1054

Query: 684  RGRAHTGMARSEDS----VVLLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGG 739
              RAHTG     DS     + +  Q   GL+        Q+H P     G ++  D P  
Sbjct: 1055 EARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA-----QEHGPRSALGGAREVPDAPPA 1109

Query: 740  -----------SPVRESHGLAQGSSEEEELPSLAFLLGSQHKL----------LPWWLPQ 778
                       SP RE  GL+  S+ E  LPS      S              L    P 
Sbjct: 1110 ACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPD 1169

Query: 779  SPVPASGLLSPEKWGPQG------THQSPSAERRGLNLAPSPANKAKKQP 822
            +P P S   S +     G       H+ PS    G  L   P N AK QP
Sbjct: 1170 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSV--LGTPLLQPPENLAKGQP 1217


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 45/134 (33%), Positives = 50/134 (37%), Gaps = 15/134 (11%)

Query: 430 PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPP-----Q 484
           PPA PR  PRG PA      P   P+   P A  A   P R  R    A   PP     Q
Sbjct: 108 PPAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166

Query: 485 PHRRAETKARL--PPPRPQRP---AETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPE 539
           P  RA+  A L  PPP P  P   A    P   PP  V       E  L P       P+
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVA----AREPPLPPPPQPPAPPQ 222

Query: 540 KQREEGKVKQPQEE 553
           +Q+      QP  E
Sbjct: 223 QQQPPPPQPQPPPE 236



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 21/125 (16%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P   PPPA     P  PPA      P   P  A    +    PPP+P  P  + + PPPQ
Sbjct: 176 PLAAPPPA-----PAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQ 230

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P          PPP        +      P  ++E V      LG S GA G   + R +
Sbjct: 231 PQ---------PPP---EGGAVRAGGAARPVSLREVV----RYLGGSGGAGGRLTRGRVQ 274

Query: 545 GKVKQ 549
           G +++
Sbjct: 275 GLLEE 279



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 36/118 (30%), Positives = 44/118 (37%), Gaps = 28/118 (23%)

Query: 423 KGPQCLPPPATPRLEPRGPPAPEVV-----------------KQPVYLPSKAGPKAQTA- 464
           +G       A P   P  PP P  V                   P   P++ GP+AQ A 
Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175

Query: 465 --CLPPPRPQRPVTKARRPPPQPHRR-----AETKARLPPPRPQRPAETKVPEEIPPE 515
               PPP P  P   A  PP  P R      A  +  LPPP PQ PA  +  +  PP+
Sbjct: 176 PLAAPPPAPAAPPAVA--PPAGPRRAPPPAVAAREPPLPPP-PQPPAPPQQQQPPPPQ 230



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 42/145 (28%), Positives = 47/145 (32%), Gaps = 30/145 (20%)

Query: 153 TTPAP--GPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTE 210
           T PAP   P   P    A APP  P      P  P+       +P  A A+         
Sbjct: 107 TPPAPPRAPRGAPAAAAAAAPP--PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGP 164

Query: 211 VGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACE 270
             P   AQ        APL    P       V PP     A P  P +AA+         
Sbjct: 165 AQPGPRAQRA------APLAAPPPAPAAPPAVAPPAGPRRAPP--PAVAAREP------- 209

Query: 271 GGWSQGLPLPPPP----PPAAQLPP 291
                  PLPPPP    PP  Q PP
Sbjct: 210 -------PLPPPPQPPAPPQQQQPP 227



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 11/51 (21%)

Query: 424 GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRP 474
           GP+  PPPA    EP  PP P    QP   P +  P       PPP+PQ P
Sbjct: 195 GPRRAPPPAVAAREPPLPPPP----QPPAPPQQQQP-------PPPQPQPP 234



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 46/169 (27%), Positives = 52/169 (30%), Gaps = 42/169 (24%)

Query: 127 GAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPL 186
           GA P   P   A  G   +   A P  TPAP P   P  V A AP   P   +   + P 
Sbjct: 105 GATPPAPP--RAPRGAPAAAAAAAPPPTPAPPPPPAP--VAAAAPARAPRAAAAAATAP- 159

Query: 187 VTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPP 246
                   PS   A         + GP     A       AP    A     G    PPP
Sbjct: 160 --------PSPGPA---------QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP 202

Query: 247 LLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPP----PPPPAAQLPP 291
            + A  P +P                     P PP    PPPP  Q PP
Sbjct: 203 AVAAREPPLPPPPQP----------------PAPPQQQQPPPPQPQPPP 235


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
          Length = 1086

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 98/417 (23%), Positives = 143/417 (34%), Gaps = 90/417 (21%)

Query: 131  VLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQ 190
            ++G GV A P    + +  +P     P P    L +    P GG                
Sbjct: 732  LVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLP---PQGG---------------- 772

Query: 191  DGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG---VVCPPPL 247
             G  PS A  + +F          +A Q + +   QAP    AP    GG      PP +
Sbjct: 773  -GKPPSSAQTAEIF----------QALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRV 821

Query: 248  LLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHG 307
             +   P  P +        +     W    P P  PP      P+  QG+  P P    G
Sbjct: 822  PIPPRPTRPHVQLSPAPPGEEETSQW----PGPASPPRVPPREPLSPQGSRTPSPLVPPG 877

Query: 308  ESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSL 367
             S L       PP  S +P       + +      A   + Q+P   A  C ++P++R  
Sbjct: 878  SSPL-------PPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPC-ILPIVRDG 929

Query: 368  ARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQC 427
             +   T               +    +R  + E  ++FL     E    ++   +  P  
Sbjct: 930  KKVSST--------------HYYLLPERPSYLERYQRFL----REAQSPEEPTPLPVPLL 971

Query: 428  LPPPATPRLEPRGPPAPEVVKQPVYLPSKA-GPKAQTACLPPPRPQRPVTKARRPPPQPH 486
            LPPP+TP      P AP    +P  +P  A  PKA  +             AR PPP+  
Sbjct: 972  LPPPSTP-----APAAPTATVRP--MPQAALDPKANFS------TNNSNPGARPPPPR-- 1016

Query: 487  RRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
                  ARL    PQR      PE   P    + + ++E+L G  L   GE  K  E
Sbjct: 1017 ----ATARL----PQRGCPGDGPEAGRP---ADKIQMVEQLFGLGLRPRGECHKVLE 1062



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 2/57 (3%)

Query: 431 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVT--KARRPPPQP 485
           P  P L P  P   ++      L  +  P++ T  LP P    PV    AR  PP P
Sbjct: 655 PVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPP 711


>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 146/630 (23%), Positives = 216/630 (34%), Gaps = 121/630 (19%)

Query: 249  LAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE 308
            L++AP  PV AA +V  +Q  E    +GL LP        LP   ++ ++ P P  A   
Sbjct: 613  LSSAPK-PVAAATIV--SQQAE----EGLTLPQDSVMTPPLPLQDTELSSAPKPVAA--- 662

Query: 309  SSLASSQAKA----PPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVL 364
            ++L S QA+     P D +  P    ++  L    KP+A   L      E L+      L
Sbjct: 663  ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT------L 716

Query: 365  RSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKG 424
               +   P + L++            S+  + +    A   +  +AEE + + +   M  
Sbjct: 717  PQDSAMTPPLPLQD---------TDLSSAPKPV---AAATLVSQQAEEGLTLPQDSAMT- 763

Query: 425  PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKAQTACLPPPRPQRPVTKARRPPP 483
                PP      +    P P      V   ++ G    Q + + PP P +    +  P P
Sbjct: 764  ----PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 819

Query: 484  QP-----HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEP 538
                    ++AE    LP    Q  A T      PP  +Q+  D+      P   A   P
Sbjct: 820  VAAATLVSQQAEEGLTLP----QDSAMT------PPLPLQD-TDLSS---APKPVAAATP 865

Query: 539  EKQREEGKVKQPQEEDWTPP----DPGLLSYIDKLCSQKDFVTKVEAVIHP--------- 585
              Q+ E  +  PQ+   T P    D G  S  + L        + EA   P         
Sbjct: 866  VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMA 925

Query: 586  -QFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLD 644
             Q + E L P P            +E+   L  + E       ++   + A   GT    
Sbjct: 926  QQEVGEALGPRPA----------PEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAA 975

Query: 645  SSSSKFAAGQGAERDVPDPQEGVGMETCPPQTT-ARDSQGRGRAHTGMARSEDS----VV 699
               +    G  A   +P+P  G G E     +   R++    RAHTG     DS     +
Sbjct: 976  QEDADSTLGMEA-LSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETL 1034

Query: 700  LLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGG-----------SPVRESHGL 748
             +  Q   GL+        Q+H P     G ++  D P             SP RE  GL
Sbjct: 1035 EVENQQEGGLKPLA-----QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGL 1089

Query: 749  AQGSSEEEELPSLAFLLGSQHKL----------LPWWLPQSPVPASGLLSPEKWGPQG-- 796
            +  S+ E  LPS      S              L    P +P P S   S +     G  
Sbjct: 1090 SGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLG 1149

Query: 797  ----THQSPSAERRGLNLAPSPANKAKKQP 822
                 H+ PS    G  L   P N AK QP
Sbjct: 1150 SVEQPHEVPSV--LGTPLLQPPENLAKGQP 1177


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 146/630 (23%), Positives = 216/630 (34%), Gaps = 121/630 (19%)

Query: 249  LAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE 308
            L++AP  PV AA +V  +Q  E    +GL LP        LP   ++ ++ P P  A   
Sbjct: 613  LSSAPK-PVAAATIV--SQQAE----EGLTLPQDSVMTPPLPLQDTELSSAPKPVAA--- 662

Query: 309  SSLASSQAKA----PPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVL 364
            ++L S QA+     P D +  P    ++  L    KP+A   L      E L+      L
Sbjct: 663  ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT------L 716

Query: 365  RSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKG 424
               +   P + L++            S+  + +    A   +  +AEE + + +   M  
Sbjct: 717  PQDSAMTPPLPLQD---------TDLSSAPKPV---AAATLVSQQAEEGLTLPQDSAMT- 763

Query: 425  PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKAQTACLPPPRPQRPVTKARRPPP 483
                PP      +    P P      V   ++ G    Q + + PP P +    +  P P
Sbjct: 764  ----PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 819

Query: 484  QP-----HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEP 538
                    ++AE    LP    Q  A T      PP  +Q+  D+      P   A   P
Sbjct: 820  VAAATIVSQQAEEGLTLP----QDSAMT------PPLPLQD-TDLSS---APKPVAAATP 865

Query: 539  EKQREEGKVKQPQEEDWTPP----DPGLLSYIDKLCSQKDFVTKVEAVIHP--------- 585
              Q+ E  +  PQ+   T P    D G  S  + L        + EA   P         
Sbjct: 866  VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMA 925

Query: 586  -QFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLD 644
             Q + E L P P            +E+   L  + E       ++   + A   GT    
Sbjct: 926  QQEVGEALGPRPA----------PEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAA 975

Query: 645  SSSSKFAAGQGAERDVPDPQEGVGMETCPPQTT-ARDSQGRGRAHTGMARSEDS----VV 699
               +    G  A   +P+P  G G E     +   R++    RAHTG     DS     +
Sbjct: 976  QEDADSTLGMEA-LSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETL 1034

Query: 700  LLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGG-----------SPVRESHGL 748
             +  Q   GL+        Q+H P     G ++  D P             SP RE  GL
Sbjct: 1035 EVENQQEGGLKPLA-----QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGL 1089

Query: 749  AQGSSEEEELPSLAFLLGSQHKL----------LPWWLPQSPVPASGLLSPEKWGPQG-- 796
            +  S+ E  LPS      S              L    P +P P S   S +     G  
Sbjct: 1090 SGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLG 1149

Query: 797  ----THQSPSAERRGLNLAPSPANKAKKQP 822
                 H+ PS    G  L   P N AK QP
Sbjct: 1150 SVEQPHEVPSV--LGTPLLQPPENLAKGQP 1177


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 146/630 (23%), Positives = 216/630 (34%), Gaps = 121/630 (19%)

Query: 249  LAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE 308
            L++AP  PV AA +V  +Q  E    +GL LP        LP   ++ ++ P P  A   
Sbjct: 613  LSSAPK-PVAAATIV--SQQAE----EGLTLPQDSVMTPPLPLQDTELSSAPKPVAA--- 662

Query: 309  SSLASSQAKA----PPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVL 364
            ++L S QA+     P D +  P    ++  L    KP+A   L      E L+      L
Sbjct: 663  ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT------L 716

Query: 365  RSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKG 424
               +   P + L++            S+  + +    A   +  +AEE + + +   M  
Sbjct: 717  PQDSAMTPPLPLQD---------TDLSSAPKPV---AAATLVSQQAEEGLTLPQDSAMT- 763

Query: 425  PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKAQTACLPPPRPQRPVTKARRPPP 483
                PP      +    P P      V   ++ G    Q + + PP P +    +  P P
Sbjct: 764  ----PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 819

Query: 484  QP-----HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEP 538
                    ++AE    LP    Q  A T      PP  +Q+  D+      P   A   P
Sbjct: 820  VAAATIVSQQAEEGLTLP----QDSAMT------PPLPLQD-TDLSS---APKPVAAATP 865

Query: 539  EKQREEGKVKQPQEEDWTPP----DPGLLSYIDKLCSQKDFVTKVEAVIHP--------- 585
              Q+ E  +  PQ+   T P    D G  S  + L        + EA   P         
Sbjct: 866  VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMA 925

Query: 586  -QFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLD 644
             Q + E L P P            +E+   L  + E       ++   + A   GT    
Sbjct: 926  QQEVGEALGPRPA----------PEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAA 975

Query: 645  SSSSKFAAGQGAERDVPDPQEGVGMETCPPQTT-ARDSQGRGRAHTGMARSEDS----VV 699
               +    G  A   +P+P  G G E     +   R++    RAHTG     DS     +
Sbjct: 976  QEDADSTLGMEA-LSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETL 1034

Query: 700  LLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGG-----------SPVRESHGL 748
             +  Q   GL+        Q+H P     G ++  D P             SP RE  GL
Sbjct: 1035 EVENQQEGGLKPLA-----QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGL 1089

Query: 749  AQGSSEEEELPSLAFLLGSQHKL----------LPWWLPQSPVPASGLLSPEKWGPQG-- 796
            +  S+ E  LPS      S              L    P +P P S   S +     G  
Sbjct: 1090 SGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLG 1149

Query: 797  ----THQSPSAERRGLNLAPSPANKAKKQP 822
                 H+ PS    G  L   P N AK QP
Sbjct: 1150 SVEQPHEVPSV--LGTPLLQPPENLAKGQP 1177


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 85/359 (23%), Positives = 140/359 (38%), Gaps = 74/359 (20%)

Query: 278 PLPPP--------PP--PAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPR 327
           P+PPP        PP  P   +P + S  +AGP P      S+     A+  P  + N  
Sbjct: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709

Query: 328 SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREW 387
            +     +      +  R LP  P+         P+L       PT+  +E     +   
Sbjct: 710 GLSVPGLV-----SVPPRLLP-GPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRP 763

Query: 388 QHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPP-----ATPRLEPRGPP 442
               ++D+    ++ E  LE ++++ + I      +G   LPPP       P + P GPP
Sbjct: 764 AFV-HYDKEEASDV-EISLESDSDDSVVIVP----EGLPPLPPPPPSGATPPPIAPTGPP 817

Query: 443 --APEVV--KQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPP 498
             +P V   ++P  LP+  GP      LPPP P         PPP P         LPPP
Sbjct: 818 TASPPVPAKEEPEELPAAPGP------LPPPPPP--------PPPVP-----GPVTLPPP 858

Query: 499 RPQRPAETKVPEEIP----PEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEED 554
           +        VPE  P    P  ++E + ++   +  S     E E++ EE + ++ +EED
Sbjct: 859 Q-------LVPEGTPGGGGPPALEEDLTVIN--INSSDEEEEEEEEEEEEEEEEEEEEED 909

Query: 555 WTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGL 613
           +   +     Y ++           E     +F EE    + +++     +D E+EE L
Sbjct: 910 FEEEEEDEEEYFEE-----------EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 55/207 (26%), Positives = 75/207 (36%), Gaps = 44/207 (21%)

Query: 123 MASNGAYPVLGPGVTANPGT-------SLSV---FTALPFTTPAP-----GPAHGPLLVT 167
           M S G  P  GP  +A PG         LSV    +  P   P P     G    P+L  
Sbjct: 683 MPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742

Query: 168 AGAPPGGPLVLSTFPSTPLVTEQDGCSPSGA-------GASNVFVQMRTEVGPVKAAQAQ 220
           +G PP         P+ P      G  P  A        AS+V + + ++          
Sbjct: 743 SGTPP---------PTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD-------SDD 786

Query: 221 TLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLP 280
           ++V+    L    P    G    PPP+    AP  P  A+  V   +  E   +   PLP
Sbjct: 787 SVVIVPEGLPPLPPPPPSGAT--PPPI----APTGPPTASPPVPAKEEPEELPAAPGPLP 840

Query: 281 PPPPPAAQLPPIVSQGNAGPWPQGAHG 307
           PPPPP   +P  V+       P+G  G
Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPG 867



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 30/117 (25%), Positives = 44/117 (37%), Gaps = 22/117 (18%)

Query: 425  PQCLPPPATP-RLEPRGPPAPEV---VKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
            P  LPPP +P +++P   P P +   V++P     +    A T        Q  V +   
Sbjct: 983  PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042

Query: 481  PP---PQPHRRAETKARLPP---------------PRPQRPAETKVPEEIPPEVVQE 519
             P   P P    E +   PP               P P+ PAE ++  E   E +QE
Sbjct: 1043 SPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQE 1099


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 120/504 (23%), Positives = 163/504 (32%), Gaps = 98/504 (19%)

Query: 428 LPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRP---QRPVTKARRPPPQ 484
           LPPP    L P  PP       P      + P  +    P P      RP+ ++   PP 
Sbjct: 441 LPPPEESPLSP--PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE------------YVDIMEELLGP-- 530
                       P  P   +    PEE PP    E                 E  L P  
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558

Query: 531 -SLGATGEPEKQR-----EEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIH 584
             L  +  PE  R     EE  +  P EE    P P          + + F    E+ + 
Sbjct: 559 EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE---------ASRLFPPFEESPLS 609

Query: 585 PQFLEELLSPDPQMDFLA-----LSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRG 639
           P   E  LSP P+   L+            EE          RL PL         P   
Sbjct: 610 PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669

Query: 640 TARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVV 699
                   S  +    A R  P P++     T PP   +  S             EDS++
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDS---PTSPPPEDSPAS----------PPPEDSLM 716

Query: 700 LLGCQDSPGL----------------RAARPTSPPQDHRPTCPGVGTKDALDLPGGSPVR 743
            L  ++SP L                 + RP  P    RP  P +  +   + P  SP  
Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ--AEEPHLSPQP 774

Query: 744 ESHGLAQGSSE-----EEELPSLAFLLGSQHKLLPWWLPQ-SPVPASGLLSPEKWGPQGT 797
           E   L     E     + E P L+      H       P  SPVP    LSP+   P+ +
Sbjct: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ---PEES 831

Query: 798 HQSPSAERRGLNLAPSPAN---KAKKQPLFGSLSPAEKTPHRGPG----------LRVSG 844
           H SP +E   L+  P  ++   + +K P    LSP  + P   PG              G
Sbjct: 832 HLSPQSEEPCLSPRPEESHLSPELEKPP----LSPRPEKPPEEPGQCPAPEELPLFPPPG 887

Query: 845 EQSLTWGLGGPSQSQKRKGDPLVS 868
           E SL+  LG P+ S+   G+P +S
Sbjct: 888 EPSLSPLLGEPALSE--PGEPPLS 909



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 131/540 (24%), Positives = 170/540 (31%), Gaps = 112/540 (20%)

Query: 282 PPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDS-------CNPRSVYENFR 334
           PPP A++L P   +  A P P+  H    L  S    PP++S        +P S  E   
Sbjct: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519

Query: 335 LW--QHYKPLARRHLPQSPDTEALSCF-------LIPVLRSLARRKPTMTL------EEG 379
           L   +   P      P SP  EA           L P    L    P          EE 
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579

Query: 380 LWRAMREWQHTSNFDRM--IFYEMAEKFLEFEAEEEMQI---QKSQWMKGPQCLPPPATP 434
                 E    S       +F    E  L    EE       + S+    P+  P    P
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639

Query: 435 RLEPRGPPAPEVVK-QPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKA 493
              P  PP PEV +  P+ + S+  P  + + L PP  + P +    PPP+  R +    
Sbjct: 640 EESPMSPP-PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS----PPPEASRLS---- 690

Query: 494 RLPPPR--PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK-QREEGKVKQP 550
             PPP   P  P     P   PPE     + + E    P L    EP+   R EG    P
Sbjct: 691 --PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE---SPLLPLPEEPQLCPRSEGPHLSP 745

Query: 551 Q-EEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQ 609
           + EE    P P                   E  + PQ  E  LSP P             
Sbjct: 746 RPEEPHLSPRP------------------EEPHLSPQAEEPHLSPQP------------- 774

Query: 610 EEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVPDPQEGVGM 669
           EE    A   E  L P  E  H    P        +     +         P P+E    
Sbjct: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS---------PVPEE---- 821

Query: 670 ETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQDHRPTCPGVG 729
               PQ        +        R E+S +    +  P   + RP  PP++         
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPP--LSPRPEKPPEE--------- 870

Query: 730 TKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSP 789
                  PG  P  E   L     E    PSL+ LLG      P   P SP+P    LSP
Sbjct: 871 -------PGQCPAPEELPLFPPPGE----PSLSPLLGEPALSEPGEPPLSPLPEELPLSP 919



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 38/141 (26%), Positives = 56/141 (39%), Gaps = 21/141 (14%)

Query: 423  KGPQCLPPP--------ATPRLEPRGPPA-PEVVKQPVYLPSKAGPKAQTACLPPPRPQR 473
            +GP  LP P            + P  PP+ P+  K+P  LPS +      A LPP  P  
Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343

Query: 474  PVTKARRPPPQPHRRAETKARL----------PPPRPQRPAETKVPEEIPPEVVQEYVDI 523
            P  +     P P R +   A+L          P   P   AET+ PE+    +V  ++D 
Sbjct: 4344 PKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ--SSLVPGHLDQ 4401

Query: 524  MEELLGPSLGATGEPEKQREE 544
            +   + P        ++ REE
Sbjct: 4402 VNGQVVPEASQLSIKQEPREE 4422



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 43/131 (32%), Positives = 50/131 (38%), Gaps = 38/131 (29%)

Query: 430  PPATPRLEPRGPPAPEVVKQPVYLPSK------AGPKAQTACLPP--PRP-------QRP 474
            PP TPR +P  PP       P  LPS       A P++Q++   P  PRP         P
Sbjct: 2381 PPLTPRPQPP-PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439

Query: 475  VTKA-------RRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEEL 527
            VT          RPP +P  R        PPRPQ           PPEV  +       L
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ-----------PPEVAFK----AGSL 2484

Query: 528  LGPSLGATGEP 538
               SLGA G P
Sbjct: 2485 AHTSLGAGGFP 2495



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 180/783 (22%), Positives = 254/783 (32%), Gaps = 143/783 (18%)

Query: 115  VVSAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGG 174
            V S  P G+A   AYP+     TA P       T  P+ +P   PA  P+L  +  P  G
Sbjct: 2171 VPSQDPFGLAP--AYPLEPRFPTAPP-------TYPPYPSPTGAPAQPPMLGASSRPGAG 2221

Query: 175  PL--VLSTFPSTPL---VTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPL 229
                  +T P TP     T      P      N+ V     VG  KA++         PL
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE---------PL 2272

Query: 230  VWQAP-GALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQ 288
            +   P G     +      L A++P         V    +  G    GL L  P    A 
Sbjct: 2273 LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSS--GTHLGGLELKTPDVFKAP 2330

Query: 289  LPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHL- 347
            L P  SQ        G   +     +QA AP     +P S  + FR   +  P A+  L 
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEP-PPAQALAP-----SPPSHPDIFRPGSYTDPYAQPPLT 2384

Query: 348  --PQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKF 405
              PQ P  E  SC  +P         P     +   R     Q  S+        +  + 
Sbjct: 2385 PRPQPPPPE--SCCALP---------PRSLPSDPFSRVPASPQSQSSSQS----PLTPRP 2429

Query: 406  LEFEAEEEMQIQKSQWMKGPQCLPP-------PATPRLEPRGPPAPEVVKQ--------- 449
            L  EA     +        P   PP       P  P  +P  P  PEV  +         
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489

Query: 450  -----PVYLPSKAGPKAQTACL-----PPPRPQRPVTKARRPPPQPHR----RAETKARL 495
                 P  LP  AGP  +         PP   + P T A    P P R    +A  +  L
Sbjct: 2490 GAGGFPAALP--AGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL 2547

Query: 496  PPPRPQR-------------PAETK-VPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
             PP PQ              P  T   P+     V           LGPS G+TGE    
Sbjct: 2548 KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGE---- 2603

Query: 542  REEGKVKQPQEEDWTPPDP-GLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
               G           PP P G L Y+    SQ+  +T          +E+   P   M  
Sbjct: 2604 -SYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSP--------VEKREDPGTGMGS 2654

Query: 601  LALSQDLEQEEGLTLAQLVEKRLPPLKEKQH-----SRAAPSRGTARLDSSSSKFAAGQG 655
               + +L   +   ++ L +  L   +++Q       R    R T R +  ++  AAG  
Sbjct: 2655 SLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAG-- 2712

Query: 656  AERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPT 715
                   P    G E   P + A +   RG+      + + S+V L      G      +
Sbjct: 2713 ----AVGPPGSWGAE---PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGS 2765

Query: 716  SPPQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWW 775
             P  D     P   T  ++D+     V  S    Q +     LP    L   Q +L   W
Sbjct: 2766 FPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLP----LQQQQQQL---W 2818

Query: 776  LPQSPVPASGL------LSPEKWGPQGTHQSPSAERRGLNL-APSPANKAKKQPLFGSLS 828
              Q    A+ +        P   GP+   Q+  +   G++   P P      +P+ G   
Sbjct: 2819 QQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG-----EPVPGPAG 2873

Query: 829  PAE 831
            PA+
Sbjct: 2874 PAQ 2876



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 44/176 (25%), Positives = 63/176 (35%), Gaps = 30/176 (17%)

Query: 425  PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
            P  LPPP +P +    PPA   + +  Y     G     + L  P  + P++    PPP+
Sbjct: 932  PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS----PPPE 987

Query: 485  PH--RRAETKARLPPPRPQRPAETKVP---EEIPPEVVQEYVDIMEELLGPSLGATGEPE 539
             +          + PP P  P     P   E +PP+           LL  SL     P 
Sbjct: 988  ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQ--------CSPLLQHSLVPQNSPP 1039

Query: 540  KQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPD 595
             Q        P     + P P  LS I K+    D     EA +H    E++  P+
Sbjct: 1040 SQ------CSPPALPLSVPSP--LSPIGKVVGVSD-----EAELHEMETEKVSEPE 1082



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 37/150 (24%), Positives = 56/150 (37%), Gaps = 20/150 (13%)

Query: 422 MKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRP 481
           ++ P   P P  P  EP   PAPE  + P++ P   G  + +  L  P    P      P
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAPE--ELPLFPP--PGEPSLSPLLGEPALSEPGEPPLSP 910

Query: 482 PPQ-----PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATG 536
            P+     P        +L PP P  P  + +     P  +      + EL  P  GA G
Sbjct: 911 LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP----LGELEYP-FGAKG 965

Query: 537 EPEKQRE------EGKVKQPQEEDWTPPDP 560
           + + +        E  +  P E + T P+P
Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEP 995



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 32/118 (27%), Positives = 43/118 (36%), Gaps = 25/118 (21%)

Query: 442  PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQ 501
            PAPE   Q  Y  + +    +    PPP       +   PPP P         L P    
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPP-------EEPSPPPSP---------LAPSPAS 4927

Query: 502  RPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQE-EDWTPP 558
             P E  V  E+P E       + E  +   L     PE  R + + + P+E ED  PP
Sbjct: 4928 PPTEPLV--ELPTE------PLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 41/123 (33%), Positives = 49/123 (39%), Gaps = 24/123 (19%)

Query: 422 MKGPQCLPPPATPRLEPRGPP----------APEVVKQPVYLPSKAGPKAQTACLPP-PR 470
           M GP  L PP  P L P GPP          AP  ++ P  +P   GP  +   LPP P 
Sbjct: 407 MPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPP-GMPGLRGPLPR--LLPPGPP 463

Query: 471 PQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGP 530
           P RP      PPP           LPP  P R    ++P   PP +      +M   L P
Sbjct: 464 PGRPPGPPPGPPP----------GLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP 513

Query: 531 SLG 533
            LG
Sbjct: 514 PLG 516



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 24/84 (28%), Positives = 26/84 (30%), Gaps = 5/84 (5%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRR 488
           PPP  P   P GPP       P   P    P      +PPPRP        RPP  P   
Sbjct: 462 PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP-----GMMRPPLVPPLG 516

Query: 489 AETKARLPPPRPQRPAETKVPEEI 512
                  PP     P     P  +
Sbjct: 517 PAPPGLFPPAPLPNPGVLSAPPNL 540


>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
          Length = 1806

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 76/342 (22%), Positives = 122/342 (35%), Gaps = 87/342 (25%)

Query: 425 PQCLPPPATPRLEPRG-------------PPAPEVVKQPVYLPSKAGPKAQTA-CLPPPR 470
           P+    PA P  +P G             PP P+      + PSKA     TA  L  PR
Sbjct: 176 PEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPR 235

Query: 471 P---QRPVTKARRPPPQPHR----RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVD- 522
           P   +RPV+       QP +     A T  ++PP  P++    K P  +  ++   + + 
Sbjct: 236 PRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRK-PRPLSMDLTARFENK 294

Query: 523 ------IMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFV 576
                 + +E  GP+ G     E+ R   K+                         +D +
Sbjct: 295 EALLRKVADEGSGPTAGDMAGLERPRAASKL------------------------DRDCL 330

Query: 577 TKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAP 636
            K EA +H          DP +DFL +++ + + +   L++  E   P       S   P
Sbjct: 331 VKAEAPLH----------DPDLDFLEVAKKIRERKEKMLSK-PEMGSPRALVGGSSGVTP 379

Query: 637 SRG------TARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTG 690
           S         A+LD    K A       + P P+ G G+E    ++   D +        
Sbjct: 380 SNDQSPWEEKAKLDPEPEKAA-------ESPSPRLGRGLELAEVKSRVADGEAAAGGEWA 432

Query: 691 MARS---------EDSVVLLGC-QDSPGLRAARPTSPPQDHR 722
             RS         EDS + L    +SP    A P++ P+  +
Sbjct: 433 SRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEK 474


>gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo
           sapiens]
          Length = 1595

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 76/342 (22%), Positives = 122/342 (35%), Gaps = 87/342 (25%)

Query: 425 PQCLPPPATPRLEPRG-------------PPAPEVVKQPVYLPSKAGPKAQTA-CLPPPR 470
           P+    PA P  +P G             PP P+      + PSKA     TA  L  PR
Sbjct: 176 PEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPR 235

Query: 471 P---QRPVTKARRPPPQPHR----RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVD- 522
           P   +RPV+       QP +     A T  ++PP  P++    K P  +  ++   + + 
Sbjct: 236 PRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRK-PRPLSMDLTARFENK 294

Query: 523 ------IMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFV 576
                 + +E  GP+ G     E+ R   K+                         +D +
Sbjct: 295 EALLRKVADEGSGPTAGDMAGLERPRAASKL------------------------DRDCL 330

Query: 577 TKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAP 636
            K EA +H          DP +DFL +++ + + +   L++  E   P       S   P
Sbjct: 331 VKAEAPLH----------DPDLDFLEVAKKIRERKEKMLSK-PEMGSPRALVGGSSGVTP 379

Query: 637 SRG------TARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTG 690
           S         A+LD    K A       + P P+ G G+E    ++   D +        
Sbjct: 380 SNDQSPWEEKAKLDPEPEKAA-------ESPSPRLGRGLELAEVKSRVADGEAAAGGEWA 432

Query: 691 MARS---------EDSVVLLGC-QDSPGLRAARPTSPPQDHR 722
             RS         EDS + L    +SP    A P++ P+  +
Sbjct: 433 SRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEK 474


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 104/407 (25%), Positives = 140/407 (34%), Gaps = 66/407 (16%)

Query: 143  SLSVFTALPFTTPA--PGPAHGPLLVTAGAP----PGGPLVLS--TFPSTPLVTEQDG-- 192
            S+ + ++LP + P   P PA  PL +   AP      GP +L+  T P  P+V    G  
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491

Query: 193  -CSPSGAGASNVFVQMRTEVGP-VKAAQAQTLVLTQAPLVWQAPG------ALCGGVVCP 244
              +PSGA  S   + +     P + ++Q     L  AP     PG        C  V+ P
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551

Query: 245  PPLLLAAAPVVPVMA-AQVVGGTQACEGGWSQGLPL------------PPPPPPAAQLPP 291
               L +  P  P  A AQ      A     +   PL            P P PP A LP 
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611

Query: 292  IVSQGNAGP------------WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHY 339
            +     A P             P    G +SLAS+     P     P S  +        
Sbjct: 1612 LAPSPGAAPVLASSQTPVPVMAPSSTPG-TSLASASPVPAPTPVLAPSST-QTMLPAPVP 1669

Query: 340  KPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFY 399
             PL     P S  T AL+  L P   +L    P+ TL  G       +       + +  
Sbjct: 1670 SPLPS---PASTQTLALAPALAP---TLGGSSPSQTLSLGTGNPQGPFP-----TQTLSL 1718

Query: 400  EMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP--PAPEVVKQPVYLPSKA 457
              A   +   A      Q      GP  L P  T  L P  P  PA  V   P +  + A
Sbjct: 1719 TPASSLVPTPA------QTLSLAPGPP-LGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771

Query: 458  GPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPA 504
             P + +A L  P   + +T +  P P     A     L P   Q PA
Sbjct: 1772 -PASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPA 1817



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 76/308 (24%), Positives = 104/308 (33%), Gaps = 47/308 (15%)

Query: 40   SGSCLMAEALHRTSPTPNSCPLPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSL 99
            SG  L+       +P   + P P P    SG   S +  T   +     S +S  PGH L
Sbjct: 1468 SGPALLTSVTPPLAPVVPAAPGP-PSLAPSGASPSASALTLGLATAPSLS-SSQTPGHPL 1525

Query: 100  GLTLGFSYCGNCQTAVVSA------QPEGMAS---NGAYPVLGPGVTANPGTSLSVFTAL 150
             L    S+     + V  A          +AS   +   P         P +S S   A 
Sbjct: 1526 LLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALAT 1585

Query: 151  PFT----------TPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGA 200
            P             P+P P   PL V A +P   P++ S+    P++        S A A
Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645

Query: 201  SNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAA 260
            S V         PV A  +     TQ  L    P  L      P P       + P +A 
Sbjct: 1646 SPV-----PAPTPVLAPSS-----TQTMLPAPVPSPL------PSPASTQTLALAPALAP 1689

Query: 261  QVVGGTQACEGGWSQGLPLPPPP------PPAAQLPPIVSQGNA---GPWPQGAHGESSL 311
             + G + +       G P  P P       PA+ L P  +Q  +   GP P G     SL
Sbjct: 1690 TLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGP-PLGPTQTLSL 1748

Query: 312  ASSQAKAP 319
            A +   AP
Sbjct: 1749 APAPPLAP 1756



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 18/102 (17%)

Query: 430  PPATPRLEPRGPPAPEVVKQP-------VYL------PSKAGPKAQTACLPPPRPQRPVT 476
            P A P L P    AP  +  P       V++      PS+  P +  AC PPP    P  
Sbjct: 2451 PAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPP-- 2508

Query: 477  KARRPPPQPHRRAETKARL---PPPRPQRPAETKVPEEIPPE 515
             A  PPP         + L   PP  P   + T +P  + PE
Sbjct: 2509 PAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPE 2550



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 19/183 (10%)

Query: 112  QTAVVSAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPL-LVTAGA 170
            +T VV   P   A  G  PV  P     PG  LS   A P  TP P P   P  L+ + +
Sbjct: 1007 RTVVVVNNPR--APLGPVPVRPP-----PGPELS---AQP--TPGPVPQVLPASLMVSAS 1054

Query: 171  PPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAP-- 228
            P G PL+ ++ P  P++       P+      V       +         TL L   P  
Sbjct: 1055 PAGPPLIPASRPPGPVLLPP--LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPA 1112

Query: 229  LVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQ 288
             V  +P    G      PL +      P  AA     T A     +  +P P P P    
Sbjct: 1113 PVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTAT--ATTTAVPAPTPAPQRLI 1170

Query: 289  LPP 291
            L P
Sbjct: 1171 LSP 1173



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 14/104 (13%)

Query: 424  GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPP- 482
            GP  + PP  P L  +  P P     P  L   A P A    +P  RP  PV      P 
Sbjct: 1020 GPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASP-AGPPLIPASRPPGPVLLPPLQPN 1078

Query: 483  --------PQPHRRAETKARLPPP----RPQRPAETKVPEEIPP 514
                    P P       +R P P    +P  PA  ++    PP
Sbjct: 1079 SGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPP 1122



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 21/71 (29%), Positives = 27/71 (38%), Gaps = 4/71 (5%)

Query: 430  PPATPRLEPRGPPAPEVVKQPVYL-PSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR- 487
            PPA  RL P  PP    + +P+ + P    P A              T    P P P R 
Sbjct: 1110 PPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRL 1169

Query: 488  --RAETKARLP 496
                + +ARLP
Sbjct: 1170 ILSPDMQARLP 1180


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 434 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 546 PAPTTPKEPAPTTPKEP 562



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 456

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 515

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 516 PTTPEEPTPTTPEEP 530



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 442 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 555 APTTPKEPAPTTPKE 569



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 341

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 379



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 340

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 341 APTTPKEPAPTAP 353



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 216 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 309 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 363

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 424 KEPAPT--TPKEP 434



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 91/431 (21%), Positives = 142/431 (32%), Gaps = 49/431 (11%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 364 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 481

Query: 544 EGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLAL 603
                    +  TP  P  L+       +K   T  E  + P   EE     P+      
Sbjct: 482 TAPT---TPKKLTPTTPEKLA---PTTPEKPAPTTPEE-LAPTTPEEPTPTTPEEPAPTT 534

Query: 604 SQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAER--DVP 661
            +          A    K   P   K+ +   P          ++     + A      P
Sbjct: 535 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594

Query: 662 DPQEGVGMETCPPQTTARDSQG----RGRAHTGMARSEDSVVLLGCQDSP------GLRA 711
            P+E     T  P +T  D       +G A T       +        +P       L+ 
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654

Query: 712 ARPTSP----PQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGS 767
             PT+P    P++  PT     T    D P  +  +E+      ++ +E  P+      +
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET----APTTPKEPAPT------T 704

Query: 768 QHKLLPWWLPQSPVPASGLLSPEKWGPQGT--HQSPSAERRGLNLAPSP--ANKAKKQPL 823
             K  P   P++P P +  +S      + T  H+SP      L+  P+P     + K+P 
Sbjct: 705 PKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 763

Query: 824 FGSLSPAEKTP 834
                P  KTP
Sbjct: 764 V----PTTKTP 770



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 459 APTTTKKPAPTTPKEP 474



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 270 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 324

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 371



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 266

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 324

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 325 PTPTTPKEP 333



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 544

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 545 EP---APTTPKEPAPTTPKEPAPTTPKETAP 572


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 475 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 587 PAPTTPKEPAPTTPKEP 603



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 497

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 556

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 557 PTTPEEPTPTTPEEP 571



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 483 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 596 APTTPKEPAPTTPKE 610



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 382

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 420



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 381

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 382 APTTPKEPAPTAP 394



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 257 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 350 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 404

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 465 KEPAPT--TPKEP 475



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 91/431 (21%), Positives = 142/431 (32%), Gaps = 49/431 (11%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 405 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 522

Query: 544 EGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLAL 603
                    +  TP  P  L+       +K   T  E  + P   EE     P+      
Sbjct: 523 TAPT---TPKKLTPTTPEKLA---PTTPEKPAPTTPEE-LAPTTPEEPTPTTPEEPAPTT 575

Query: 604 SQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAER--DVP 661
            +          A    K   P   K+ +   P          ++     + A      P
Sbjct: 576 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635

Query: 662 DPQEGVGMETCPPQTTARDSQG----RGRAHTGMARSEDSVVLLGCQDSP------GLRA 711
            P+E     T  P +T  D       +G A T       +        +P       L+ 
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695

Query: 712 ARPTSP----PQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGS 767
             PT+P    P++  PT     T    D P  +  +E+      ++ +E  P+      +
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET----APTTPKEPAPT------T 745

Query: 768 QHKLLPWWLPQSPVPASGLLSPEKWGPQGT--HQSPSAERRGLNLAPSP--ANKAKKQPL 823
             K  P   P++P P +  +S      + T  H+SP      L+  P+P     + K+P 
Sbjct: 746 PKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 804

Query: 824 FGSLSPAEKTP 834
                P  KTP
Sbjct: 805 V----PTTKTP 811



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 500 APTTTKKPAPTTPKEP 515



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 311 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 365

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 412



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 307

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 365

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 366 PTPTTPKEP 374



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 585

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 586 EP---APTTPKEPAPTTPKEPAPTTPKETAP 613


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 527 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 639 PAPTTPKEPAPTTPKEP 655



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 549

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 609 PTTPEEPTPTTPEEP 623



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 535 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 648 APTTPKEPAPTTPKE 662



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 434

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 472



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 433

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 434 APTTPKEPAPTAP 446



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 309 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 402 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 456

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 517 KEPAPT--TPKEP 527



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 91/431 (21%), Positives = 142/431 (32%), Gaps = 49/431 (11%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 457 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 574

Query: 544 EGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLAL 603
                    +  TP  P  L+       +K   T  E  + P   EE     P+      
Sbjct: 575 TAPT---TPKKLTPTTPEKLA---PTTPEKPAPTTPEE-LAPTTPEEPTPTTPEEPAPTT 627

Query: 604 SQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAER--DVP 661
            +          A    K   P   K+ +   P          ++     + A      P
Sbjct: 628 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687

Query: 662 DPQEGVGMETCPPQTTARDSQG----RGRAHTGMARSEDSVVLLGCQDSP------GLRA 711
            P+E     T  P +T  D       +G A T       +        +P       L+ 
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747

Query: 712 ARPTSP----PQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGS 767
             PT+P    P++  PT     T    D P  +  +E+      ++ +E  P+      +
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET----APTTPKEPAPT------T 797

Query: 768 QHKLLPWWLPQSPVPASGLLSPEKWGPQGT--HQSPSAERRGLNLAPSP--ANKAKKQPL 823
             K  P   P++P P +  +S      + T  H+SP      L+  P+P     + K+P 
Sbjct: 798 PKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 856

Query: 824 FGSLSPAEKTP 834
                P  KTP
Sbjct: 857 V----PTTKTP 863



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 552 APTTTKKPAPTTPKEP 567



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 363 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 464



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 417

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 418 PTPTTPKEP 426



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 637

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 638 EP---APTTPKEPAPTTPKEPAPTTPKETAP 665


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 568 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 680 PAPTTPKEPAPTTPKEP 696



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 590

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 650 PTTPEEPTPTTPEEP 664



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 576 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 689 APTTPKEPAPTTPKE 703



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 475

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 513



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 474

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 475 APTTPKEPAPTAP 487



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 350 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 443 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 497

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 558 KEPAPT--TPKEP 568



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 91/431 (21%), Positives = 142/431 (32%), Gaps = 49/431 (11%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 498 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 615

Query: 544 EGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLAL 603
                    +  TP  P  L+       +K   T  E  + P   EE     P+      
Sbjct: 616 TAPT---TPKKLTPTTPEKLA---PTTPEKPAPTTPEE-LAPTTPEEPTPTTPEEPAPTT 668

Query: 604 SQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAER--DVP 661
            +          A    K   P   K+ +   P          ++     + A      P
Sbjct: 669 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728

Query: 662 DPQEGVGMETCPPQTTARDSQG----RGRAHTGMARSEDSVVLLGCQDSP------GLRA 711
            P+E     T  P +T  D       +G A T       +        +P       L+ 
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788

Query: 712 ARPTSP----PQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGS 767
             PT+P    P++  PT     T    D P  +  +E+      ++ +E  P+      +
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET----APTTPKEPAPT------T 838

Query: 768 QHKLLPWWLPQSPVPASGLLSPEKWGPQGT--HQSPSAERRGLNLAPSP--ANKAKKQPL 823
             K  P   P++P P +  +S      + T  H+SP      L+  P+P     + K+P 
Sbjct: 839 PKKPAP-TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 897

Query: 824 FGSLSPAEKTP 834
                P  KTP
Sbjct: 898 V----PTTKTP 904



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 593 APTTTKKPAPTTPKEP 608



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 404 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 505



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 458

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 459 PTPTTPKEP 467



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 678

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 679 EP---APTTPKEPAPTTPKEPAPTTPKETAP 706


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 83/358 (23%), Positives = 122/358 (34%), Gaps = 74/358 (20%)

Query: 131 VLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQ 190
           ++G GV A P    + +  +P     P P    L +    P GG                
Sbjct: 654 LVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLP---PQGG---------------- 694

Query: 191 DGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG---VVCPPPL 247
            G  PS A  + +F          +A Q + +   QAP    AP    GG      PP +
Sbjct: 695 -GKPPSSAQTAEIF----------QALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRV 743

Query: 248 LLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHG 307
            +   P  P +        +     W    P P  PP      P+  QG+  P P    G
Sbjct: 744 PIPPRPTRPHVQLSPAPPGEEETSQW----PGPASPPRVPPREPLSPQGSRTPSPLVPPG 799

Query: 308 ESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSL 367
            S L       PP  S +P       + +      A   + Q+P   A  C ++P++R  
Sbjct: 800 SSPL-------PPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPC-ILPIVRDG 851

Query: 368 ARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQC 427
            +   T               +    +R  + E  ++FL     E    ++   +  P  
Sbjct: 852 KKVSST--------------HYYLLPERPSYLERYQRFL----REAQSPEEPTPLPVPLL 893

Query: 428 LPPPATPRLEPRGPPAPEVVKQPVYLPSKA-GPKAQTA---CLPPPRPQRPVTKARRP 481
           LPPP+TP      P AP    +P  +P  A  PKA  +     P  RP  P   AR P
Sbjct: 894 LPPPSTP-----APAAPTATVRP--MPQAALDPKANFSTNNSNPGARPPPPRATARLP 944



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 16/85 (18%)

Query: 438 PRGPPAPEVVKQPVYLPSKAG---PKAQTACLPPPRPQRPVTKARRPPPQPHRRAE---- 490
           P G PAP         PS  G   P+       PPRP RP  +    PP     ++    
Sbjct: 721 PAGSPAPS--------PSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGP 772

Query: 491 -TKARLPPPRPQRPAETKVPEEIPP 514
            +  R+PP  P  P  ++ P  + P
Sbjct: 773 ASPPRVPPREPLSPQGSRTPSPLVP 797



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 2/57 (3%)

Query: 431 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVT--KARRPPPQP 485
           P  P L P  P   ++      L  +  P++ T  LP P    PV    AR  PP P
Sbjct: 577 PVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPP 633


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,721,501
Number of Sequences: 37866
Number of extensions: 3234648
Number of successful extensions: 26889
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 249
Number of HSP's successfully gapped in prelim test: 1069
Number of HSP's that attempted gapping in prelim test: 15844
Number of HSP's gapped (non-prelim): 8960
length of query: 878
length of database: 18,247,518
effective HSP length: 111
effective length of query: 767
effective length of database: 14,044,392
effective search space: 10772048664
effective search space used: 10772048664
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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