Guide to the Human Genome
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Search of human proteins with 239743620

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]
         (285 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]           581   e-166
gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]           376   e-104
gi|239754940 PREDICTED: hypothetical protein [Homo sapiens]           272   2e-73
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     66   3e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    66   4e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 62   8e-10
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    60   2e-09
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]     58   1e-08
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             57   1e-08
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]            57   1e-08
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     57   2e-08
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     57   2e-08
gi|33356148 formin-like 1 [Homo sapiens]                               57   2e-08
gi|56549694 enabled homolog isoform a [Homo sapiens]                   57   2e-08
gi|39930375 enabled homolog isoform b [Homo sapiens]                   57   2e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                57   2e-08
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       56   3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   5e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    55   5e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    55   5e-08
gi|22027541 programmed cell death 7 [Homo sapiens]                     54   1e-07
gi|33286436 gametogenetin [Homo sapiens]                               54   1e-07
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    54   2e-07
gi|33286446 opioid growth factor receptor [Homo sapiens]               54   2e-07
gi|11386183 WAS protein family, member 2 [Homo sapiens]                54   2e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  54   2e-07
gi|55750041 atrophin-1 [Homo sapiens]                                  54   2e-07
gi|157168329 formin 1 [Homo sapiens]                                   53   3e-07
gi|160707881 formin 2 [Homo sapiens]                                   53   3e-07
gi|153792074 proline rich 12 [Homo sapiens]                            53   3e-07

>gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score =  581 bits (1498), Expect = e-166
 Identities = 285/285 (100%), Positives = 285/285 (100%)

Query: 1   MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60
           MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP
Sbjct: 1   MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60

Query: 61  RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120
           RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR
Sbjct: 61  RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120

Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180
           PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA
Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180

Query: 181 LGPALTRIHNVEGSKDSWNCGQGLLLLMLSAAPVRTPGLRLASSAGFASPFEMALTGLFN 240
           LGPALTRIHNVEGSKDSWNCGQGLLLLMLSAAPVRTPGLRLASSAGFASPFEMALTGLFN
Sbjct: 181 LGPALTRIHNVEGSKDSWNCGQGLLLLMLSAAPVRTPGLRLASSAGFASPFEMALTGLFN 240

Query: 241 LVLGNDCFPQGMNGTPGIQVMWTDRVNIITEYKQERKANITTARR 285
           LVLGNDCFPQGMNGTPGIQVMWTDRVNIITEYKQERKANITTARR
Sbjct: 241 LVLGNDCFPQGMNGTPGIQVMWTDRVNIITEYKQERKANITTARR 285


>gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 195

 Score =  376 bits (966), Expect = e-104
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 1   MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60
           MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP
Sbjct: 1   MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60

Query: 61  RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120
           RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR
Sbjct: 61  RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120

Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180
           PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA
Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEA 180

Query: 181 LGP 183
           LGP
Sbjct: 181 LGP 183


>gi|239754940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 159

 Score =  272 bits (696), Expect = 2e-73
 Identities = 138/162 (85%), Positives = 140/162 (86%), Gaps = 4/162 (2%)

Query: 1   MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60
           MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP
Sbjct: 1   MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60

Query: 61  RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120
           RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR
Sbjct: 61  RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120

Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162
           PSSPPP P  P  P       S+L AP PP     P  S+ A
Sbjct: 121 PSSPPPSPPSPPVP----TAQSSLPAPWPPQGPRSPAPSLRA 158



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 22/113 (19%)

Query: 76  QPRRRSPGPQGGGGG-----DIASP----LP-PALQPRGAPAVPAAPSPGPLPARPSSPP 125
           Q  R     +GGG G      +  P    LP PAL   G   +     P P  A P +P 
Sbjct: 6   QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGI----RPAPAAAHPPAPR 61

Query: 126 PRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178
            RP+            SALAA +P    P PQG          P + +  GAP
Sbjct: 62  ERPAAAR--------LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 54/156 (34%), Positives = 70/156 (44%), Gaps = 27/156 (17%)

Query: 48  IRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107
           ++P    A PPAP   P  A  +A AAA P   +P P         +   PA  PR A A
Sbjct: 99  VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP----VAAAAPARAPRAAAA 154

Query: 108 VPAAPSPGPLPARP----------SSPPPRPSL------PSGPHRPVLPPSALAAPRPPL 151
              AP P P PA+P          ++PPP P+       P+GP R   PP A+AA  PPL
Sbjct: 155 AATAP-PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRR--APPPAVAAREPPL 211

Query: 152 ARPLPQGSVTAREQE---QRPRSRRRAGAPEALGPA 184
             P PQ     ++Q+    +P+     GA  A G A
Sbjct: 212 PPP-PQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAA 246



 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 52/143 (36%), Positives = 60/143 (41%), Gaps = 14/143 (9%)

Query: 50  PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP-PALQPRGAPAV 108
           PAP AA   AP   P AA  +A A   P    PGP+      +A+P P PA  P  AP  
Sbjct: 137 PAPVAA--AAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAP-- 192

Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQR 168
           PA P   P PA  +  PP P     P +P  PP     P PP  +P P+G         R
Sbjct: 193 PAGPRRAPPPAVAAREPPLPP----PPQPPAPPQQ-QQPPPPQPQPPPEGGAVRAGGAAR 247

Query: 169 PRSRRRA----GAPEALGPALTR 187
           P S R      G     G  LTR
Sbjct: 248 PVSLREVVRYLGGSGGAGGRLTR 270



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 48/182 (26%), Positives = 63/182 (34%), Gaps = 40/182 (21%)

Query: 35  LPGPALVVAGLDGIRPAPAAAHP----------PAPRERPAAARLSALAAAQPRRRSPGP 84
           LP P    A       + +AA P           + R R A   L  +     RR  P P
Sbjct: 7   LPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEP 66

Query: 85  QGGGG-----------------GDIASPLPPALQP--RGA--PAVPAAPSPGPLPARPSS 123
           +                     G I+      +QP  RGA  PA P AP   P  A  ++
Sbjct: 67  ERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAA 126

Query: 124 PPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQ--EQRPRSRRRAGAPEAL 181
           PPP P+ P        PP+ +AA  P  A      + TA       +P  R +  AP A 
Sbjct: 127 PPPTPAPPP-------PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAA 179

Query: 182 GP 183
            P
Sbjct: 180 PP 181



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 21/115 (18%)

Query: 49  RPAPAAAH-------PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQ 101
           RPA A  H       P + +ER            Q   R P P G G   + S    A+ 
Sbjct: 355 RPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAP-GSGTRQVFSMA--AMN 411

Query: 102 PRGAPAV----PAAPSPGPLPARPSSPPPRPSLPSGPHRPV-LPPSALAAPRPPL 151
             G  A     P +PSP PL      PP +P+LP     P   PP     P  P+
Sbjct: 412 KEGGTASVATGPDSPSPVPL------PPGKPALPGADGTPFGCPPGRKEKPSDPV 460



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 21/99 (21%)

Query: 50  PAPAAAH---PPAPRERPAAARLSALAAAQPRR-----RSPGPQGGGGGDIASPLPPALQ 101
           PAP       PP P+  P    + A  AA+P       R  G  GG GG +       L 
Sbjct: 218 PAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLL 277

Query: 102 PR-------------GAPAVPAAPSPGPLPARPSSPPPR 127
                          GA A+P    PG  P   S+ P R
Sbjct: 278 EEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSR 316


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 46/126 (36%), Positives = 57/126 (45%), Gaps = 14/126 (11%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
            P P A  PP+P+  PAA      A+  P    P P+   G   A+PL     P+GAP  P
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK---GSPAATPL-----PKGAPTTP 1060

Query: 110  AA--PSPGPLPARPS---SPPPRPSLPSGPHRPVLPPSALAAPRPPLAR-PLPQGSVTAR 163
            AA  PSP   PA PS   +P P  + P  P      PS   AP PP A  P P+G +   
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 164  EQEQRP 169
              +  P
Sbjct: 1121 PHKGAP 1126



 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 13/123 (10%)

Query: 52   PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI--ASPLPPALQPRGAPAVP 109
            P AA PP+P+  PAA  L   A   P    P P+GG        +P PPA  P      P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094

Query: 110  AAPSPGPLPARPSSPPPRPS--LPSGPHRPVLPPSALAAPRPPLARP-LPQGSVTAREQE 166
            A PSP   P  P++ PP P   L + PH+         AP  P A P  P+G +     +
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHK--------GAPTTPAATPPSPKGGLATPPPK 1146

Query: 167  QRP 169
              P
Sbjct: 1147 GAP 1149



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 41/116 (35%), Positives = 47/116 (40%), Gaps = 9/116 (7%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG--GDIASPLPPALQPRGAPA 107
            P P AA PP+P+  PA       A   P    P P+GG        +P PPA  P     
Sbjct: 940  PTPPAATPPSPKGGPATPS-PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998

Query: 108  VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR-PLPQGSVTA 162
             PA PSP   P  P+  PP P        P   P    A  PP A  P P+GS  A
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPK-----GSPAATPFPKGASTPPAATPPSPKGSPAA 1049



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 14/141 (9%)

Query: 30   PGGFCLPG---PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQG 86
            P G  LP    P   V  L   +  PA    PAP++ PA +  S+  + +  R +P P+G
Sbjct: 875  PKGVTLPPKETPTPSVVNLPFPKEGPAT---PAPKQAPALSMTSS--SPKKARATPAPKG 929

Query: 87   --GGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPR----PSLPSGPHRPVLP 140
                     +P PPA  P      PA PSP   P  P++ PP     P+ PS    P  P
Sbjct: 930  IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989

Query: 141  PSALAAPRPPLARPLPQGSVT 161
             +   +P+   A P P+G+ T
Sbjct: 990  AATPPSPKGGPATPSPKGAPT 1010



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 43/141 (30%), Positives = 58/141 (41%), Gaps = 30/141 (21%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-------GGGDIASPLPPALQ- 101
            P P AA PP+P+   A       A   P    P P+GG       G     +  PP+ + 
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKG-APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161

Query: 102  ------PRGAPAVPAA-----------PSPGPLPARPSSPPPRP----SLPSGPHRPVLP 140
                  P+GAP  PAA           PSP   P  P++ PP P    + PS    P  P
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221

Query: 141  PSALAAPRPPLARPLPQGSVT 161
             +   +P+  LA P P+G+ T
Sbjct: 1222 AATPPSPKGGLATPSPKGAPT 1242



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 39/113 (34%), Positives = 48/113 (42%), Gaps = 12/113 (10%)

Query: 58   PAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIA--SPLPPALQPRGAPAVPAAPSPG 115
            PAP+  PA+      A   P    P P+GG        +P PPA  P      PA PSP 
Sbjct: 925  PAPKGIPASPSPKG-APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983

Query: 116  PLPARPSSPPPRPSLPSGPHRP----VLPPSALAAPRP---PLARPLPQGSVT 161
              P  P++ PP P    GP  P       P A+  P P   P A P P+G+ T
Sbjct: 984  GAPTPPAATPPSPK--GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 38/109 (34%), Positives = 46/109 (42%), Gaps = 15/109 (13%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
            P PA   PP+P+  PA +     A   P    P P+G  G       PP   P+GAP  P
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPG------TPP---PKGAPTPP 1336

Query: 110  AAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQG 158
            A   P P    P+ P   PS   GP      PS+   P PP A P  +G
Sbjct: 1337 AVTPPSP-KGTPTLPATTPSSKGGP----TTPSSKEGPTPPAATPSHKG 1380



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 41/117 (35%), Positives = 49/117 (41%), Gaps = 18/117 (15%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
            P P AA PP+P+  PA       A   P    P P+GG         P    P+GAP  P
Sbjct: 963  PTPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGG---------PATPSPKGAPTPP 1012

Query: 110  AA--PSPGPLPA-----RPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR-PLPQG 158
            A   PSP   PA     + +S PP  + PS    P   P    AP  P A  P P+G
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 41/116 (35%), Positives = 49/116 (42%), Gaps = 27/116 (23%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
            P   AA PP+P+   A       A   P    P P+GG    +A+P      P+GAP  P
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGG----LATP-----SPKGAPTTP 1221

Query: 110  AA-----------PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARP 154
            AA           PSP   P  P++ PP P    GP  P  PP    AP PP A P
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPK--GGPATP--PPK--GAPTPPAATP 1271



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 15/137 (10%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
            P   A  PP+P+E PA  +++  ++ +    +P P G       +P  PA+ P     VP
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG-------APTLPAVIPSSPKEVP 1517

Query: 110  AAPSPGPLPARPSSPPPRPSLPS--GPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQ 167
            A PS    P  P++       P+   P   ++PP A+  P P     +P    T +E   
Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP-AMTVPSPKKTPAIP----TPKEAPA 1572

Query: 168  RPRSRRRAGAPEALGPA 184
             P S + A +P A+ P+
Sbjct: 1573 TP-SSKEASSPPAVTPS 1588



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 48/170 (28%), Positives = 63/170 (37%), Gaps = 28/170 (16%)

Query: 31   GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90
            GG   P P           P   AA PP+P+  PA       A   P    P  +GG   
Sbjct: 1230 GGLATPSPKGA--------PTTPAATPPSPKGGPATPPPKG-APTPPAATPPSLKGG--- 1277

Query: 91   DIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSL--PSGPHRPVLPPSALAAPR 148
             +A+P P    P  A   P +P  GP  + P   P  P+   PS    P  PP   A   
Sbjct: 1278 -LATP-PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 149  PPLARPLPQGSVT-------AREQEQRPRSRRRAGAPEAL-----GPALT 186
            P +  P P+G+ T       ++     P S+     P A      GPA+T
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 42/144 (29%), Positives = 52/144 (36%), Gaps = 20/144 (13%)

Query: 52   PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL---------PPALQP 102
            PA   P      PA   LS   A        G      GD+  P          P    P
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452

Query: 103  RGAPAVPAAPSPGPLPA-RPSSP--PPRP---SLPSGPHRPVLPPSALAAPRPPLARPLP 156
            +G PA P++     LPA  P SP  PP P   +  S P +    P+ + AP  P   P  
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP-- 1510

Query: 157  QGSVTAREQEQRPRSRRRAGAPEA 180
                + +E    P SRR   AP A
Sbjct: 1511 ---SSPKEVPATPSSRRDPIAPTA 1531



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 42/159 (26%), Positives = 56/159 (35%), Gaps = 9/159 (5%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            P    +P P    A +   + APA          PA    +   A  P+     P     
Sbjct: 1550 PPAMTVPSPKKTPA-IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608

Query: 90   GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP-SLPSGPHRPVLPPSALAAPR 148
                +P PPA+ P      PA P+P      P+SPP  P SL   P  P      + A  
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAP---KGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665

Query: 149  PPLARPLP--QGSVTARE--QEQRPRSRRRAGAPEALGP 183
            P  ++ LP  +G    +E      P S     AP   GP
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 44/154 (28%), Positives = 55/154 (35%), Gaps = 32/154 (20%)

Query: 50   PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-----------GGGDIAS---- 94
            P P AA PP+P+  P        A   P    P P+G            GG    S    
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKG-APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368

Query: 95   PLPPALQP--RGAPAV--------PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSAL 144
            P PPA  P  +G PA+        PA PSP   P  P+  P  P     P  PV    A 
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK--KAPATPVTREGAA 1426

Query: 145  AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178
               +  L  P    +VT    ++ P +    G P
Sbjct: 1427 TPSKGDLTPP----AVTPVSLKKAPATSAPKGGP 1456



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 42/158 (26%), Positives = 55/158 (34%), Gaps = 21/158 (13%)

Query: 47   GIRPAPAAAH---PPAPRERP---AAARLSALAAAQPRRRSPGPQ-------GGGGGDIA 93
            G + +PA  H   PP+P+  P   A   LS      P + +P P          G    A
Sbjct: 845  GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904

Query: 94   SPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPR------PSLPSGPHRPVLPPSALAAP 147
                PAL    +    A  +P P    P+SP P+       + P  P      PS   AP
Sbjct: 905  PKQAPALSMTSSSPKKARATPAP-KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963

Query: 148  RPPLAR-PLPQGSVTAREQEQRPRSRRRAGAPEALGPA 184
             PP A  P P+G       +  P            GPA
Sbjct: 964  TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 38/132 (28%), Positives = 52/132 (39%), Gaps = 20/132 (15%)

Query: 53   AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112
            A+  P  P   P +   + L AA   +  P P+       A+P PP        ++P AP
Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS--AAPSPPV-------SLPLAP 1804

Query: 113  SPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRP-----PLARPLP-QGSVTAREQE 166
            SP P     + PP +  LPS P   +  PS   AP       PL  P P  G V  +   
Sbjct: 1805 SPVP-----TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859

Query: 167  QRPRSRRRAGAP 178
                + + AG P
Sbjct: 1860 VNMPTPKSAGIP 1871



 Score = 35.0 bits (79), Expect = 0.075
 Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 15/159 (9%)

Query: 30  PGGFCLPGPALVVAG-LDGIRPAPA---AAHPPAPRERPAAARLSALA-AAQPRRRSPGP 84
           P   C P   LV+A  +    P+P+   A  PP  ++    +  SALA  A   +  P  
Sbjct: 714 PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773

Query: 85  QGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSAL 144
             G     +S                A SP PL    S    RP    G   P  P   L
Sbjct: 774 DSGASATASSK---------GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNL 824

Query: 145 AAPRPPL-ARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182
           ++P  P+ A  LP+ S++ +  +  P +      P   G
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863



 Score = 34.7 bits (78), Expect = 0.098
 Identities = 44/197 (22%), Positives = 71/197 (36%), Gaps = 50/197 (25%)

Query: 35  LPGPALVVAG-------LDGIRP----APAAAHPP-APRERPAAARLSA----------- 71
           +P P+L  AG       +DGI      AP A+ P   P E   A+  ++           
Sbjct: 734 VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793

Query: 72  -----LAAAQPRRRSPGPQGGGG-----GDIASPLPP---------ALQPRGAPAVPAAP 112
                ++ +   +R P  +G  G     G+++SP+ P         +L  +G+   PA  
Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853

Query: 113 SPGPLPARPSSPPPRPSLPSGPHRPVLPPSA--------LAAPRPPLARPLPQGSVTARE 164
                P+   +P P    P  P    LPP          L  P+   A P P+ +     
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913

Query: 165 QEQRPRSRRRAGAPEAL 181
               P+  R   AP+ +
Sbjct: 914 TSSSPKKARATPAPKGI 930


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 41/107 (38%), Positives = 45/107 (42%), Gaps = 5/107 (4%)

Query: 52  PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAA 111
           P    PPAP  RP     + L    P    P  +  G   +  PLP  L P   P  P  
Sbjct: 411 PPLGPPPAPPLRPPGPP-TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469

Query: 112 PSPGPLPARPSSPPPR---PSLPSGPHRPVLPPSALAAPRPPLARPL 155
           P PGP P  P  PPPR   P LP  P  P +PP      RPPL  PL
Sbjct: 470 PPPGPPPGLPPGPPPRGPPPRLPP-PAPPGIPPPRPGMMRPPLVPPL 515



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 50/170 (29%), Positives = 61/170 (35%), Gaps = 34/170 (20%)

Query: 36  PGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG-GDIAS 94
           PGP        G+ P P    PP  R       +  L    PR   PGP  G   G    
Sbjct: 424 PGPPT------GLPPGPPPGAPPFLRP----PGMPGLRGPLPRLLPPGPPPGRPPGPPPG 473

Query: 95  P---LPPALQPRGAP------AVPAAPSPGPLPARPSSPPPRPSLPSG--PHRPVLPPSA 143
           P   LPP   PRG P      A P  P P P   RP   PP    P G  P  P+  P  
Sbjct: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGV 533

Query: 144 LAAPRPPLARPLPQ------------GSVTAREQEQRPRSRRRAGAPEAL 181
           L+AP   + RP                +++A+ Q   P++      P AL
Sbjct: 534 LSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTAL 583



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 14/129 (10%)

Query: 55  AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSP 114
           A   + ++    +     + A  ++++P PQ      I +P  P   P G P  P    P
Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424

Query: 115 GPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRR 174
           GP    P  PPP          P L P  +   R PL R LP G    R     P     
Sbjct: 425 GPPTGLPPGPPPGAP-------PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP----- 472

Query: 175 AGAPEALGP 183
            G P  L P
Sbjct: 473 -GPPPGLPP 480


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 58/166 (34%), Positives = 61/166 (36%), Gaps = 17/166 (10%)

Query: 2   PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPA-------LVVAGLDGIRPAPAA 54
           PGG   A F    RG G     R     PGG   PGPA          AG    RP    
Sbjct: 189 PGGSSRAAFPQGGRGRG-----RFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP 243

Query: 55  AHPPAPRERPAAAR-LSALAAAQPRR--RSPGPQGGGGGDIASPLPPALQPRGAPAVPA- 110
             PP P   P   + L    A  P R  R P P    G     P    L P   P VP  
Sbjct: 244 PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGY 303

Query: 111 APSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLP 156
            P PGP P +   PPP    P  P  P+ PP  LA P P L  P P
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP-PHLPGPPP 348



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 32/84 (38%), Positives = 34/84 (40%), Gaps = 9/84 (10%)

Query: 80  RSPGPQGGGGGDIASPL--PPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRP 137
           R PGP G GG     P    P   P G P  P    PGP P     PPP    P+   RP
Sbjct: 216 RFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPPLAGPPNRGDRP 273

Query: 138 VLPPSALAAPRP---PLARPLPQG 158
             PP  L   +P   P   PLP G
Sbjct: 274 --PPPVLFPGQPFGQPPLGPLPPG 295



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/79 (37%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 80  RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVL 139
           R+  PQGG G        P       PA P  P P P PA  + P P P  P GP  P  
Sbjct: 194 RAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPP-PFPAGQTPPRP-PLGPPGPPGPPG 251

Query: 140 PPSALAAPRPPLARPLPQG 158
           PP       PPLA P  +G
Sbjct: 252 PPPPGQVLPPPLAGPPNRG 270



 Score = 32.0 bits (71), Expect = 0.64
 Identities = 36/129 (27%), Positives = 40/129 (31%), Gaps = 12/129 (9%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAPAAAH-----PPAPRERPAAARLSALAAAQPRRRSPGP 84
           P G   PGP   V G  G  P P         PP P        L       P    PGP
Sbjct: 288 PLGPLPPGPPPPVPGY-GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP 346

Query: 85  QGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARP-SSPPPRPSLPSGPHRPVLPPSA 143
             G         P    P     +P + S GP P  P   PPP      GP     P   
Sbjct: 347 PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP-----PGRE 401

Query: 144 LAAPRPPLA 152
           +   R PL+
Sbjct: 402 MDTARTPLS 410


>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
          Length = 651

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 58/159 (36%), Positives = 63/159 (39%), Gaps = 32/159 (20%)

Query: 16  GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-----LS 70
           GGG G     GVG  G    PGPA    G     PAP    PP P +  AA R     LS
Sbjct: 10  GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRP--PPEPDDAAAALRLALDQLS 67

Query: 71  AL-----------AAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA-APSPGPLP 118
           AL            AA     + G  G  GG    P+PP     GAP   A A +PG LP
Sbjct: 68  ALGLGGAGDTDEEGAAGDGAAAAG--GADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLP 125

Query: 119 ------ARPSSPPPRPSLPS-----GPHRPVLPPSALAA 146
                 + P  PPPRPS P       PH   L P  L A
Sbjct: 126 LLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLA 164



 Score = 30.0 bits (66), Expect = 2.4
 Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 32/137 (23%)

Query: 35  LPGPALVVAGLDGIRPAPAAAH------PPAPRERPAAARLSALAAAQPRRRSPGPQGGG 88
           +P  A + A  +   P PA +        P P   PAA    +  A  PR     P+ GG
Sbjct: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGP---PAAGARRSSGAGTPRHSPTLPEPGG 522

Query: 89  GGDIASPLPPALQPRGAP----AVPAAPSPGP--------------LPARPSSPPPRPSL 130
              +   LP  L  RGAP    A+   P  GP              LP+ P++    P  
Sbjct: 523 ---LRLELP--LSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLD 577

Query: 131 PSGPHRPVLPPSALAAP 147
                    PPSA +AP
Sbjct: 578 SGASENSRKPPSASSAP 594



 Score = 29.3 bits (64), Expect = 4.1
 Identities = 26/78 (33%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 7   AARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPA--PAAAHPPAPRERP 64
           AA  GAA  GG  G      V   G      P L  A   G  P   P A+ PP P  RP
Sbjct: 82  AAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRP 141

Query: 65  AAARLSALAAAQPRRRSP 82
           +   + A  A  P    P
Sbjct: 142 SPPDVFAGFAPHPAALGP 159


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 44/118 (37%), Positives = 50/118 (42%), Gaps = 19/118 (16%)

Query: 31  GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90
           GG  LP P  +V G  G R  P    PP P           +A   P  R P P G GG 
Sbjct: 322 GGNQLPRPP-IVGGNKG-RSGPL---PPVPL---------GIAPPPPTPRGPPPPGRGG- 366

Query: 91  DIASPLPPALQPRGAPAVPAAPSPG--PLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146
               P PP    R  P  P  P  G  P+P  P  PPP PS  +GP  P LPP+ + A
Sbjct: 367 --PPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPA 422



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 43/132 (32%), Positives = 49/132 (37%), Gaps = 21/132 (15%)

Query: 44  GLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIAS-PL---PPA 99
           GL+ +R       P  P   P+           PR    G   G  G +   PL   PP 
Sbjct: 299 GLEAVRQEMRRQEPLPPPPPPSRG-----GNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP 353

Query: 100 LQPRGAPAV-PAAPSPGPLPAR----PSSPPP----RPSLPSGPHRPVLPPSALAAPRPP 150
             PRG P      P P P PA     P  PPP     P +P  P  P  PPS+   P PP
Sbjct: 354 PTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPP 413

Query: 151 LARPLPQGSVTA 162
              PLP   V A
Sbjct: 414 ---PLPPALVPA 422


>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 389

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/182 (34%), Positives = 73/182 (40%), Gaps = 41/182 (22%)

Query: 55  AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP---AVPAA 111
           A P AP   P A       A QPR   P P        +  LPP   P G P   A+P  
Sbjct: 106 ADPAAPPSSPHAPTRPPPQAVQPRPSEPTPG-------SEALPPGSLPEGEPRPYALPPR 158

Query: 112 PSPGPLPAR---PSSP-PPRPSLPSGPHRPVLPPS--ALAAPRPPLARPLPQGSVT---- 161
            SP P P R   P SP PPRP  PS P     PPS  A  +PR P+  P P+ +V     
Sbjct: 159 ESPAPRPFRWGDPFSPAPPRPQPPSRP--AAQPPSRPAFRSPR-PVRGPHPRRAVVVAVL 215

Query: 162 ----AREQEQRPRSRRRAGAPEALGPALTRIHNVEGSKDSWNCGQGLLLLMLSAAPVRTP 217
               A  ++      RR G    L P   R               GLLL++L AA V+ P
Sbjct: 216 FGVQAPRRDVAEGGLRRDGRRPGLAPQRGR--------------GGLLLVVLHAATVQRP 261

Query: 218 GL 219
            L
Sbjct: 262 RL 263



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 4/62 (6%)

Query: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRP----PLARPLPQGSVTAREQEQRPRSRRRAG 176
           P SP    + PS PH P  PP     PRP    P +  LP GS+   E        R + 
Sbjct: 102 PVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESP 161

Query: 177 AP 178
           AP
Sbjct: 162 AP 163



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 1/58 (1%)

Query: 122 SSPPPRPSLPSGPHRPVLPPSALAAP-RPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178
           S+P    +LP  P  P  PPS+  AP RPP     P+ S      E  P      G P
Sbjct: 93  SAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEP 150


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 47/147 (31%), Positives = 52/147 (35%), Gaps = 22/147 (14%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAP----AAAHPPAPRER----PAAARLSALAAAQPRRRS 81
           PGG C+  P  +  G     P P    A   PP P       P+ + L    A  P    
Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 672

Query: 82  PG--------PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG 133
           PG        P   G   I  P PP     G P     P P PLP  P  PPP P  P G
Sbjct: 673 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP-----PPPPPLPGGPGIPPP-PPFPGG 726

Query: 134 PHRPVLPPSALAAPRPPLARPLPQGSV 160
           P  P  PP     P PP    +P   V
Sbjct: 727 PGIPPPPPGMGMPPPPPFGFGVPAAPV 753



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 44/139 (31%), Positives = 49/139 (35%), Gaps = 26/139 (18%)

Query: 26  GVGEPGGFCLPGPALVVAGLDGIRPAPAAAH-PPAPRERPAAARLSALAAAQPRRRSPGP 84
           GVG P    LPG   +        P P +A  PP P   P +A +            P P
Sbjct: 651 GVGIPSPSSLPGGTAIPPP----PPLPGSARIPPPPPPLPGSAGI------------PPP 694

Query: 85  QGGGGGDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPRPSLPSGPHRPVL 139
                G+   P PP   P G    P  P PG     P P     PPP P     P  PVL
Sbjct: 695 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVL 754

Query: 140 P----PSALAAPRPPLARP 154
           P    P  L  P   L RP
Sbjct: 755 PFGLTPKKLYKPEVQLRRP 773



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 16/81 (19%)

Query: 94  SPLPPA--LQPRGAPAVPAAPSPG------PLPARPSSPPPRPSLPSGPHRPVLPPSALA 145
           +P+PPA  L       +P  P+PG      P P  P  PPP P        P LP     
Sbjct: 571 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI 630

Query: 146 APRPPLA--------RPLPQG 158
           +P PPL+         PLP+G
Sbjct: 631 SPPPPLSGDATIPPPPPLPEG 651



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 31/96 (32%), Positives = 34/96 (35%), Gaps = 32/96 (33%)

Query: 90  GDIASPLPPALQPRGAPAVPAA---PSPGPLPARPSSPPPRP------------------ 128
           GD  +P PP   P   P +P      SP  LP   +  PP P                  
Sbjct: 594 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 653

Query: 129 -----SLPSG---PHRPVLPPSALAAPRPPLARPLP 156
                SLP G   P  P LP SA   P PP   PLP
Sbjct: 654 IPSPSSLPGGTAIPPPPPLPGSARIPPPPP---PLP 686



 Score = 31.6 bits (70), Expect = 0.83
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 10/66 (15%)

Query: 93  ASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA 152
           A  +PP++ P  AP  PA     PLP    +  P P  P     P  PP     P PP  
Sbjct: 560 AITVPPSV-PSRAPVPPA----PPLPGDSGTIIPPPPAPGDSTTPPPPP-----PPPPPP 609

Query: 153 RPLPQG 158
            PLP G
Sbjct: 610 PPLPGG 615


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 47/147 (31%), Positives = 52/147 (35%), Gaps = 22/147 (14%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAP----AAAHPPAPRER----PAAARLSALAAAQPRRRS 81
           PGG C+  P  +  G     P P    A   PP P       P+ + L    A  P    
Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681

Query: 82  PG--------PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG 133
           PG        P   G   I  P PP     G P     P P PLP  P  PPP P  P G
Sbjct: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP-----PPPPPLPGGPGIPPP-PPFPGG 735

Query: 134 PHRPVLPPSALAAPRPPLARPLPQGSV 160
           P  P  PP     P PP    +P   V
Sbjct: 736 PGIPPPPPGMGMPPPPPFGFGVPAAPV 762



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 44/139 (31%), Positives = 49/139 (35%), Gaps = 26/139 (18%)

Query: 26  GVGEPGGFCLPGPALVVAGLDGIRPAPAAAH-PPAPRERPAAARLSALAAAQPRRRSPGP 84
           GVG P    LPG   +        P P +A  PP P   P +A +            P P
Sbjct: 660 GVGIPSPSSLPGGTAIPPP----PPLPGSARIPPPPPPLPGSAGI------------PPP 703

Query: 85  QGGGGGDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPRPSLPSGPHRPVL 139
                G+   P PP   P G    P  P PG     P P     PPP P     P  PVL
Sbjct: 704 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVL 763

Query: 140 P----PSALAAPRPPLARP 154
           P    P  L  P   L RP
Sbjct: 764 PFGLTPKKLYKPEVQLRRP 782



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 16/81 (19%)

Query: 94  SPLPPA--LQPRGAPAVPAAPSPG------PLPARPSSPPPRPSLPSGPHRPVLPPSALA 145
           +P+PPA  L       +P  P+PG      P P  P  PPP P        P LP     
Sbjct: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI 639

Query: 146 APRPPLA--------RPLPQG 158
           +P PPL+         PLP+G
Sbjct: 640 SPPPPLSGDATIPPPPPLPEG 660



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 31/96 (32%), Positives = 34/96 (35%), Gaps = 32/96 (33%)

Query: 90  GDIASPLPPALQPRGAPAVPAA---PSPGPLPARPSSPPPRP------------------ 128
           GD  +P PP   P   P +P      SP  LP   +  PP P                  
Sbjct: 603 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 662

Query: 129 -----SLPSG---PHRPVLPPSALAAPRPPLARPLP 156
                SLP G   P  P LP SA   P PP   PLP
Sbjct: 663 IPSPSSLPGGTAIPPPPPLPGSARIPPPPP---PLP 695



 Score = 31.6 bits (70), Expect = 0.83
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 10/66 (15%)

Query: 93  ASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA 152
           A  +PP++ P  AP  PA     PLP    +  P P  P     P  PP     P PP  
Sbjct: 569 AITVPPSV-PSRAPVPPA----PPLPGDSGTIIPPPPAPGDSTTPPPPP-----PPPPPP 618

Query: 153 RPLPQG 158
            PLP G
Sbjct: 619 PPLPGG 624


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 53/163 (32%), Positives = 59/163 (36%), Gaps = 29/163 (17%)

Query: 49  RPAPAAAHPPAPRERPAAARLSALAAAQPRR----RSPG--------------PQGGG-- 88
           RP      PPA   RP+A  L      +       R PG              P GG   
Sbjct: 458 RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAP 517

Query: 89  --GGDIASPLP---PALQPR-GAPAVPAAPSPG---PLPARPSSPPPRPSLPSGPHRPVL 139
             G    SP P   PA +P  GA   P  P PG   P  A PS+PP  P LP  P  P  
Sbjct: 518 TPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPA 577

Query: 140 PPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182
           PP     P PP   P P G+         P      G P+ALG
Sbjct: 578 PPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 40/120 (33%), Positives = 45/120 (37%), Gaps = 23/120 (19%)

Query: 25  VGVGEPGGFCLPGPALVVAG-----LDGIRPAPAAAHPP--------APRERPAAARLSA 71
           V V  P G   P P +              PAP AA PP        +P+E P     SA
Sbjct: 506 VAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPP----SA 561

Query: 72  LAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLP 131
              A P   SP P        A PLP  L P   P  P   + GP+P  P  PPP P  P
Sbjct: 562 PPQAPPLPGSPEPPP------APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGP 615


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 17/129 (13%)

Query: 53  AAAHPPAPRERP-------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--- 102
           ++A  PA  E P       ++A    L AA     +P  QG   G +A P PP L P   
Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPA 324

Query: 103 RGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS--V 160
           + + A+P  P P P P  PS+ PP P     P  P LP      P PP A PLP     +
Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPP-----PPPPPLPNQVPPPPPPPPAPPLPASGFFL 379

Query: 161 TAREQEQRP 169
            +  ++ RP
Sbjct: 380 ASMSEDNRP 388



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 28/85 (32%), Positives = 30/85 (35%)

Query: 50  PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
           P   AA  PA         L  LA   P    PGP          P PP   P  +   P
Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348

Query: 110 AAPSPGPLPARPSSPPPRPSLPSGP 134
             P P PLP +   PPP P  P  P
Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLP 373


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 17/129 (13%)

Query: 53  AAAHPPAPRERP-------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--- 102
           ++A  PA  E P       ++A    L AA     +P  QG   G +A P PP L P   
Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPA 324

Query: 103 RGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS--V 160
           + + A+P  P P P P  PS+ PP P     P  P LP      P PP A PLP     +
Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPP-----PPPPPLPNQVPPPPPPPPAPPLPASGFFL 379

Query: 161 TAREQEQRP 169
            +  ++ RP
Sbjct: 380 ASMSEDNRP 388



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 28/85 (32%), Positives = 30/85 (35%)

Query: 50  PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
           P   AA  PA         L  LA   P    PGP          P PP   P  +   P
Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348

Query: 110 AAPSPGPLPARPSSPPPRPSLPSGP 134
             P P PLP +   PPP P  P  P
Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLP 373


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 63/199 (31%), Positives = 76/199 (38%), Gaps = 28/199 (14%)

Query: 6   QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAA-AHPPAPRERP 64
           Q  R G +   G  G +  VG   P G  +PG  +   GL G + AP    H  AP   P
Sbjct: 618 QQGRPGPSGVAGPQGEKGDVGPAGPPG--VPGSVVQQEGLKGEQGAPGPRGHQGAPG--P 673

Query: 65  AAARLSALAAAQPRRRSPGPQG--GGGGDIASPLPPALQ----PRGAPAVPAAPSPGPLP 118
             AR       + R   PG QG  G  GD+  P  P L     P G P VP  P PG  P
Sbjct: 674 PGAR--GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731

Query: 119 ARPSS-------PPPRPSLP---SGPHRPVLPPSALAAPRPPLARPLP-----QGSVTAR 163
             P          PP P+ P    GP+ P  PP     P       LP     +G +  +
Sbjct: 732 GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791

Query: 164 EQEQRPRSRRRAGAPEALG 182
               RP  +  AG P A G
Sbjct: 792 GLAGRPGEKGEAGLPGAPG 810



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 58/204 (28%), Positives = 73/204 (35%), Gaps = 27/204 (13%)

Query: 2    PGGVQAARFGAAVRGGGAGRRVRVGV----GEPGGFCLPGPALVV--AGLDGIRPAPAAA 55
            P G Q  R GA    G  G +   GV    G PG    PG   +   AG  GI+ +P   
Sbjct: 1166 PQGSQGER-GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224

Query: 56   HPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA----A 111
             PP P+       +      + R   PGP G  G      LP     RG P        +
Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284

Query: 112  PSPGP--------LPARPSSP----PPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS 159
             +PGP        LP +   P       P+ P GP  P  PP    +P  P   P P G+
Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP-GEPGPSGT 1343

Query: 160  VTAREQEQRPRSRRRAGAPEALGP 183
               +  +    S    G P  LGP
Sbjct: 1344 PGQKGSKGENGS---PGLPGFLGP 1364



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 49/178 (27%), Positives = 57/178 (32%), Gaps = 31/178 (17%)

Query: 28   GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQG- 86
            G PG    PG    V G  G    P +   P  R  P          A     SPGP G 
Sbjct: 910  GAPGAAGNPGAPGHV-GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP 968

Query: 87   -GGGGDIASPLPPALQPRGAPAVPAAPS-PGPLPARPSSPPPR----------------- 127
             G  G    P PP     G P +  +P  PGPL  + +    R                 
Sbjct: 969  RGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028

Query: 128  -PSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPA 184
             P +P  P     P   +A P  P   P  +GS         P SR   G P   GPA
Sbjct: 1029 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS---------PGSRGLPGFPGPQGPA 1077



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 69/248 (27%), Positives = 80/248 (32%), Gaps = 54/248 (21%)

Query: 28   GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87
            GE G   LPG       L G R     A P  P   P    L       P  R PG QG 
Sbjct: 822  GEKGELGLPG-------LKGDRGEKGEAGPAGPPGLPGTTSLFT-----PHPRMPGEQGP 869

Query: 88   GG--GDIASPLPPALQPRGAPAVPAAPS--PGPLPARPSSPPP----RPSLPS--GPHRP 137
             G  GD   P  P LQ R     P  P+  PG      +   P     P  P   G   P
Sbjct: 870  KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP 929

Query: 138  VLPPSALAAP--RPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPALTRIHNVEGSK 195
              PP ++ AP  R    +   +G   A  +E  P      G P A G        + G  
Sbjct: 930  SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG--------LPGPP 981

Query: 196  DSWNCGQGLLLLMLSAAPVRTPGLRLASSAGFASPFEM-----ALTGLFNLVLGNDCFPQ 250
                 G+              PGLR   S G   P         + G  N  LG  C  +
Sbjct: 982  GKGKDGE--------------PGLR--GSPGLPGPLGTKAACGKVRGSENCALGGQCV-K 1024

Query: 251  GMNGTPGI 258
            G  G PGI
Sbjct: 1025 GDRGAPGI 1032



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 42/147 (28%), Positives = 53/147 (36%), Gaps = 31/147 (21%)

Query: 1    MPGGVQAARFGAAVRGGG----AGRRVRVGVGEPGGFCLPG----PALVVAGLDGIRPAP 52
            +PG +        VRG       G+ V+   G PG    PG    P + VAG       P
Sbjct: 997  LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAG------PP 1050

Query: 53   AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112
              + PP  +  P +  L            PGPQG  G D A   P    P G P + +  
Sbjct: 1051 GPSGPPGDKGSPGSRGLPGF---------PGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101

Query: 113  SPGPLPAR--------PSSPPPRPSLP 131
            SPG +           P  PP  P LP
Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLP 1128



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 41/158 (25%), Positives = 52/158 (32%), Gaps = 28/158 (17%)

Query: 28   GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87
            GE G   LPG    + G DG         P  PR  P                +PG +G 
Sbjct: 1291 GESGAMGLPGQE-GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349

Query: 88   GGGDIASPLPPALQPRGAPAVP---AAPSPGPLPARPSSP----------------PP-- 126
             G + +  LP  L PRG P  P     P    +P +P  P                PP  
Sbjct: 1350 KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 1409

Query: 127  --RPSLPSGP----HRPVLPPSALAAPRPPLARPLPQG 158
              +P  P  P    H  ++ P  L     P+  P P G
Sbjct: 1410 KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447



 Score = 32.7 bits (73), Expect = 0.37
 Identities = 54/194 (27%), Positives = 62/194 (31%), Gaps = 33/194 (17%)

Query: 6    QAARFGAAVRGGGAGRRVRVGV----GEPGGFCLPGPALVVAGLDGIRPAPAAAH----- 56
            Q    GA    G  G    VG     G PG    PG      G DG R    AA      
Sbjct: 905  QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG-LRGTPGKDGERGEKGAAGEEGSP 963

Query: 57   -PPAPRERPAAARLSALAA----AQPRRRS----PGPQGG--------GGGDIASPLPPA 99
             P  PR  P A  L          +P  R     PGP G         G  + A      
Sbjct: 964  GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV 1023

Query: 100  LQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG----PHRPVLPPSALAAPRPPLARPL 155
               RGAP +P +P     P    + PP PS P G    P    LP      P+ P  R  
Sbjct: 1024 KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP--GFPGPQGPAGRDG 1081

Query: 156  PQGSVTAREQEQRP 169
              G+   R    +P
Sbjct: 1082 APGNPGERGPPGKP 1095



 Score = 32.7 bits (73), Expect = 0.37
 Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 25/130 (19%)

Query: 28   GEPGGFCLPGP-ALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAA-----------A 75
            G+PG   LPGP      G  G+R +P    P   +      R S   A           A
Sbjct: 970  GDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029

Query: 76   QPRRRSPGPQGGGGGDIASPLPPALQP--------RGAPAVPAAPSPGPLPARPSSP--- 124
                 SPG +G  G  +A P  P+  P        RG P  P    P      P +P   
Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089

Query: 125  --PPRPSLPS 132
              P +P L S
Sbjct: 1090 GPPGKPGLSS 1099



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 60/206 (29%)

Query: 19  AGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPR 78
           AG +  +GV  P G  LPGP      +  I P  A    P P+       +      +  
Sbjct: 480 AGEKGEMGVAGPMG--LPGPK---GDIGAIGPVGA----PGPKGEKGDVGIGPFGQGEKG 530

Query: 79  RRS----PGPQGGGG--------GDIASP-LPPALQPRGAPAVPAAPSPGPLPARPSSP- 124
            +     PGP G  G        G++  P LP  +  RG    P  P P   P R  +P 
Sbjct: 531 EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGP---PGRVGAPG 587

Query: 125 ----------------------PPRPSLPSGPHRPVLPPSALAAPR------PPLARPLP 156
                                 P +P       RP   PS +A P+       P   P  
Sbjct: 588 LQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRP--GPSGVAGPQGEKGDVGPAGPPGV 645

Query: 157 QGSVTARE----QEQRPRSRRRAGAP 178
            GSV  +E    ++  P  R   GAP
Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGAP 671


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 47/134 (35%), Positives = 64/134 (47%), Gaps = 13/134 (9%)

Query: 47  GIRPAPAAA-HPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--R 103
           G R +P +  H PAP + P+ +  +  A   P  +SP PQ        SP+PP   P  R
Sbjct: 331 GQRHSPLSQRHSPAP-QCPSPSPPARAAPPCPPCQSPVPQR------RSPVPPCPSPQQR 383

Query: 104 GAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALA-APRPPLARPLPQGSVTA 162
            +PA P+ PSP  +P R S  PP    PS   R  +PPS  A  PRPP   P  + ++  
Sbjct: 384 RSPASPSCPSP--VPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAE 441

Query: 163 REQEQRPRSRRRAG 176
           R   + P    +AG
Sbjct: 442 RAYAKPPSHHVKAG 455



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 39/118 (33%), Positives = 47/118 (39%), Gaps = 13/118 (11%)

Query: 68  RLSALAAAQPR--RRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP 125
           RL  L++ Q R  R     Q   GG   SP    L  R +PA P  PSP P PAR + P 
Sbjct: 307 RLRELSSLQGRILRTLLQEQARSGGQRHSP----LSQRHSPA-PQCPSPSP-PARAAPPC 360

Query: 126 PRPSLPSGPHRPVLPPSALAAPR-----PPLARPLPQGSVTAREQEQRPRSRRRAGAP 178
           P    P    R  +PP      R     P    P+PQ         Q P  +RR+  P
Sbjct: 361 PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVP 418


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 48/139 (34%), Positives = 54/139 (38%), Gaps = 17/139 (12%)

Query: 35  LPGPALVVAGLDGIRPAPAAAHPP--APRERPAAARLSALAAAQPRRR------------ 80
           LP P L        +  PA A PP  AP   PA+  LS LA   P+              
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440

Query: 81  SPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG--PLPARPSSPPPRPSLPSGPHRPV 138
           SP P        + P  P + P   P   A PS    PL   PS P   P  PS    P 
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500

Query: 139 LPPSALAAPRPPLARPLPQ 157
            PP  LAAP   LA+P PQ
Sbjct: 501 APPP-LAAPPLQLAKPPPQ 518



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 44/135 (32%), Positives = 53/135 (39%), Gaps = 34/135 (25%)

Query: 53  AAAHPPAPRERPAAARLSALAAAQ--PRRRSPGPQGG--GGGDIASPLPPA-LQPRGAPA 107
           A AHP  P+ +     L AL   Q  P R+   P  G      +A+P P A LQ +  P 
Sbjct: 265 APAHPSQPKPKG----LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT 320

Query: 108 VPAAPSPG--------PLPARPSSPPPRPSLPSGPHRPVLPPSAL--------------- 144
           +PA P           PLP  P SP   PSL + P  P  PPS                 
Sbjct: 321 LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380

Query: 145 --AAPRPPLARPLPQ 157
             + P  PLA P PQ
Sbjct: 381 LPSPPLSPLATPPPQ 395



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 54/197 (27%), Positives = 71/197 (36%), Gaps = 37/197 (18%)

Query: 19  AGRRVRVGVGEPGGFCLPGPALV----VAGLD-GI-RPAPAAA-HPPAPRERPAAARLSA 71
           AG R       PG    P PA+      AG + G+ RPAP+A   PP    R + +  S 
Sbjct: 158 AGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 72  LAAAQPR---RRSPGPQGG-----------GGGDIASPLPPALQPRGAPAVPAAPS---- 113
            +  +P    RR P   GG               ++SP       RG P  PA PS    
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274

Query: 114 --------PGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLP-QGSVTARE 164
                   P   P R  + P    L S P     P +AL +  PP     P   S+T + 
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334

Query: 165 QEQRPRSRRRAGAPEAL 181
               P +     AP +L
Sbjct: 335 ATPLPLAPPSPSAPPSL 351



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 8/112 (7%)

Query: 51  APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110
           +P A+ P +P   P +    +LAA   +     P        A+P P A  P  AP +  
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 111 APSPGPLPARPSSPPPRPSLPSGP-----HRPVLPPSALAAPRPPLARPLPQ 157
           A  P   P   ++PP + +LPS P       P  P ++L  P  PLA P PQ
Sbjct: 513 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASL--PMSPLATPPPQ 561



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 51/145 (35%), Positives = 60/145 (41%), Gaps = 22/145 (15%)

Query: 52  PAAAHPP--APRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
           P+ A PP   P   PA+  +S  A   P+  +P P        A PL  A  P  AP   
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQ--APPPLA------APPLQLAKPPPQAPPAL 523

Query: 110 AAPSPGPLPARPSS-PPPRPSLPSGPHRPVLPPSALAAPRPP----LARPLPQ--GSVTA 162
           A P    LP+ P+S P   P  PS      LP S LA P P     LA PL Q   S  A
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579

Query: 163 REQEQRPRSRRRAGAPEAL-GPALT 186
               Q PR     G   ++ GP LT
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLT 604



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 48/165 (29%), Positives = 60/165 (36%), Gaps = 17/165 (10%)

Query: 28  GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87
           G   G   PGP     G  G+R +  A    A  +   A + SAL+A   RR + GP  G
Sbjct: 118 GRASGTTRPGPL----GQKGLRIS--AEETVARGKATEAPKRSALSAGA-RRDTSGPTPG 170

Query: 88  GGGDIASPLPP-ALQPRGAPAVPAAPSPGPLPARPSSPP--PRPSLPSGPHRPVLPPSAL 144
                 +P P  A + R A      P P P  ARP  P   PR S+ S        PS  
Sbjct: 171 ------TPSPAMARRSRAAGTEVGLPRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPA 223

Query: 145 AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPALTRIH 189
           A  RP     L + +  +      P S      P A G      H
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 51/178 (28%), Positives = 63/178 (35%), Gaps = 28/178 (15%)

Query: 38  PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-GGGDIASPL 96
           PA    GL  + P P  +  P P   PAA R+   A A  R+      GG GG  I    
Sbjct: 17  PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74

Query: 97  PPALQPRGAPAVPAAPSPGP---------LPARPSSPPP--RPSLPSGPHRPVLPPSALA 145
           P A   R A      P+  P          PA+ +SP P   P   SG  RP   P    
Sbjct: 75  PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP--GPLGQK 132

Query: 146 APRPPLARPLPQGSVTAREQEQRPRSRRRAGA--------PEALGPALTRIHNVEGSK 195
             R      + +G  T    E   RS   AGA        P    PA+ R     G++
Sbjct: 133 GLRISAEETVARGKAT----EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 33/97 (34%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 37  GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL 96
           GP L +A   G  P P+ + P +    P  A  S+ A + P        G  GG  ASP 
Sbjct: 600 GPRLTLALAPGPPPPPSRS-PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658

Query: 97  PPALQPRGAPAVPAAPSPGPLP-----ARPSSPPPRP 128
           P A     A   PAA S GP P       P +P P P
Sbjct: 659 PDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 692



 Score = 35.0 bits (79), Expect = 0.075
 Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 26/146 (17%)

Query: 38  PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97
           PAL    L  +   PA+    AP    A+  +S LA       +P PQ           P
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA-------TPPPQA----------P 563

Query: 98  PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPP--SALAAPRPPLARPL 155
           P L    AP +   PSP   PA P+   PR     GP   V  P  +   AP PP   P 
Sbjct: 564 PVL---AAPLLQVPPSP---PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPS 616

Query: 156 PQGSVTAREQEQRPRSRRRAGAPEAL 181
              S T    +    S      PE L
Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEEL 642



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 38/170 (22%)

Query: 50  PAPAAAHPPAPRERPAAARLSALAAAQPRRR-----SPGPQGGGGGDIASPLPP------ 98
           P P A  PP+P   P+   L +  A  P +      SP  Q       + PL P      
Sbjct: 337 PLPLA--PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394

Query: 99  ------ALQPRGA-PAVPAAPSPGPLPA---------------RPSSPPPRPSLP---SG 133
                 AL P  A P+ PA+P   PL                  P SPPP P +    S 
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 134 PHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGP 183
           P  P + PSA    + P +   P   V        P S      P+A  P
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504



 Score = 33.1 bits (74), Expect = 0.29
 Identities = 42/139 (30%), Positives = 53/139 (38%), Gaps = 22/139 (15%)

Query: 105 APAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA-RPLPQGSVTAR 163
           A   PAA +PG L  RP    PRP  P  P    +  +A A  R PLA R    G  T  
Sbjct: 13  AARTPAARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 164 EQEQRPRSRRRAGA----PEALGPALTRIHNVEGSKDSWNCGQGLLLLMLSAAPVRTPGL 219
           E   R    R AG     P +  PA  R      +K++            S  PV +PG 
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT------------SPGPVSSPG- 118

Query: 220 RLASSAGFASPFEMALTGL 238
               ++G   P  +   GL
Sbjct: 119 ---RASGTTRPGPLGQKGL 134


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 48/139 (34%), Positives = 54/139 (38%), Gaps = 17/139 (12%)

Query: 35  LPGPALVVAGLDGIRPAPAAAHPP--APRERPAAARLSALAAAQPRRR------------ 80
           LP P L        +  PA A PP  AP   PA+  LS LA   P+              
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401

Query: 81  SPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG--PLPARPSSPPPRPSLPSGPHRPV 138
           SP P        + P  P + P   P   A PS    PL   PS P   P  PS    P 
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 139 LPPSALAAPRPPLARPLPQ 157
            PP  LAAP   LA+P PQ
Sbjct: 462 APPP-LAAPPLQLAKPPPQ 479



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 40/117 (34%), Positives = 51/117 (43%), Gaps = 16/117 (13%)

Query: 50  PAPAAAHPPAPR---ERPAAARLSALAA--AQPRRRSPGPQGGGGGDI--ASPLPPALQP 102
           P+PAA   P+     +RPA+  LS+ A   + P R  P  +G        + P P  LQ 
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270

Query: 103 RGAPAVP-----AAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARP 154
              P V      AAP+ GPL + P + P     PS P  P  PPS    P PP   P
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPS----PSAPPSPSAPPSLQTLPSPPATPP 323



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 8/112 (7%)

Query: 51  APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110
           +P A+ P +P   P +    +LAA   +     P        A+P P A  P  AP +  
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473

Query: 111 APSPGPLPARPSSPPPRPSLPSGP-----HRPVLPPSALAAPRPPLARPLPQ 157
           A  P   P   ++PP + +LPS P       P  P ++L  P  PLA P PQ
Sbjct: 474 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASL--PMSPLATPPPQ 522



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 51/145 (35%), Positives = 60/145 (41%), Gaps = 22/145 (15%)

Query: 52  PAAAHPP--APRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
           P+ A PP   P   PA+  +S  A   P+  +P P        A PL  A  P  AP   
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQ--APPPLA------APPLQLAKPPPQAPPAL 484

Query: 110 AAPSPGPLPARPSS-PPPRPSLPSGPHRPVLPPSALAAPRPP----LARPLPQ--GSVTA 162
           A P    LP+ P+S P   P  PS      LP S LA P P     LA PL Q   S  A
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540

Query: 163 REQEQRPRSRRRAGAPEAL-GPALT 186
               Q PR     G   ++ GP LT
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLT 565



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 48/165 (29%), Positives = 60/165 (36%), Gaps = 17/165 (10%)

Query: 28  GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87
           G   G   PGP     G  G+R +  A    A  +   A + SAL+A   RR + GP  G
Sbjct: 109 GRASGTTRPGPL----GQKGLRIS--AEETVARGKATEAPKRSALSAGA-RRDTSGPTPG 161

Query: 88  GGGDIASPLPP-ALQPRGAPAVPAAPSPGPLPARPSSPP--PRPSLPSGPHRPVLPPSAL 144
                 +P P  A + R A      P P P  ARP  P   PR S+ S        PS  
Sbjct: 162 ------TPSPAMARRSRAAGTEVGLPRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPA 214

Query: 145 AAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPALTRIH 189
           A  RP     L + +  +      P S      P A G      H
Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 53/190 (27%), Positives = 67/190 (35%), Gaps = 18/190 (9%)

Query: 2   PGGVQAARFGAAVRGGGAGRR-VRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAH---- 56
           P  V  A        G  GR+ +    G  GG  +P  A         RP PA+      
Sbjct: 36  PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP-PASGRGERA 94

Query: 57  PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPA------LQPRGAPAVPA 110
           PPA    P        A+   R   PGP G  G  I++    A         R A +  A
Sbjct: 95  PPAKNTSPGPVSSPGRASGTTR---PGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151

Query: 111 A-PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQ--EQ 167
              + GP P  PS    R S  +G    +  P+  A PRPP   P    S  +     E 
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211

Query: 168 RPRSRRRAGA 177
            P +RRR  A
Sbjct: 212 SPAARRRPSA 221



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 48/169 (28%), Positives = 61/169 (36%), Gaps = 19/169 (11%)

Query: 38  PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-GGGDIASPL 96
           PA    GL  + P P  +  P P   PAA R+   A A  R+      GG GG  I    
Sbjct: 17  PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74

Query: 97  PPALQPRGAPAVPAAPSPGPLPARPSSPPP--RPSLPSGPHRPVLPPSALAAPRPPLARP 154
           P A   R +    +       PA+ +SP P   P   SG  RP   P      R      
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP--GPLGQKGLRISAEET 132

Query: 155 LPQGSVTAREQEQRPRSRRRAGA--------PEALGPALTRIHNVEGSK 195
           + +G  T    E   RS   AGA        P    PA+ R     G++
Sbjct: 133 VARGKAT----EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 33/97 (34%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 37  GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL 96
           GP L +A   G  P P+ + P +    P  A  S+ A + P        G  GG  ASP 
Sbjct: 561 GPRLTLALAPGPPPPPSRS-PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619

Query: 97  PPALQPRGAPAVPAAPSPGPLP-----ARPSSPPPRP 128
           P A     A   PAA S GP P       P +P P P
Sbjct: 620 PDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653



 Score = 35.4 bits (80), Expect = 0.058
 Identities = 46/170 (27%), Positives = 60/170 (35%), Gaps = 38/170 (22%)

Query: 50  PAPAAAHPPAPRERPAAARLSALAAAQPRRR-----SPGPQGGGGGDIASPLPP------ 98
           P+P+A  PP+P   P+   L +  A  P +      SP  Q       + PL P      
Sbjct: 298 PSPSA--PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355

Query: 99  ------ALQPRGA-PAVPAAPSPGPLPA---------------RPSSPPPRPSLP---SG 133
                 AL P  A P+ PA+P   PL                  P SPPP P +    S 
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 134 PHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGP 183
           P  P + PSA    + P +   P   V        P S      P+A  P
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465



 Score = 35.0 bits (79), Expect = 0.075
 Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 26/146 (17%)

Query: 38  PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97
           PAL    L  +   PA+    AP    A+  +S LA       +P PQ           P
Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA-------TPPPQA----------P 524

Query: 98  PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPP--SALAAPRPPLARPL 155
           P L    AP +   PSP   PA P+   PR     GP   V  P  +   AP PP   P 
Sbjct: 525 PVL---AAPLLQVPPSP---PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPS 577

Query: 156 PQGSVTAREQEQRPRSRRRAGAPEAL 181
              S T    +    S      PE L
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEEL 603



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 2/75 (2%)

Query: 105 APAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLA-RPLPQGSVTAR 163
           A   PAA +PG L  RP    PRP  P  P    +  +A A  R PLA R    G  T  
Sbjct: 13  AARTPAARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 164 EQEQRPRSRRRAGAP 178
           E   R    R +  P
Sbjct: 72  ESAPRAGPTRTSRPP 86


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 58/179 (32%), Positives = 70/179 (39%), Gaps = 23/179 (12%)

Query: 7   AARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAA 66
           AAR G    G G G     G G+P G   PG A  + G   +  +  AA P         
Sbjct: 167 AARAGPGP-GPGPGPGPGPGPGKPAG---PGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222

Query: 67  ARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPP 126
           A L  L    P+  +PG        + +  PPA     AP+ PAAP+P    A P  PPP
Sbjct: 223 AALLPL----PKPAAPGTVIQTPPFVGAAAPPA---PAAPSPPAAPAPAAPAAAPPPPPP 275

Query: 127 RP-SLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPA 184
            P +L   P  P  PP+A  A  PP           A  Q         A AP A GPA
Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPP-----------AAAQNGGSAGAAPAPAPAAGGPA 323



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 50/172 (29%), Positives = 57/172 (33%), Gaps = 48/172 (27%)

Query: 28  GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRR------- 80
           G P G    GPA    G  G  P P    PPA R RP            PRR        
Sbjct: 65  GSPAGAAGAGPAAPAEGAPGAAPEP----PPAGRARPGGGGPQRPGPPSPRRPLVPAGPA 120

Query: 81  ------SPGPQGGGGGDIASPLPPALQ----PRGAPAVPAAPS----------PGPLPAR 120
                  P P+G  G    +P+P A      P  APA PA P+          PGP P  
Sbjct: 121 PPAAKLRPPPEGSAGS--CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178

Query: 121 PSSPPPRPSLPSGP---------------HRPVLPPSALAAPRPPLARPLPQ 157
              P P P  P+GP               H    P  +L    P    PLP+
Sbjct: 179 GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 44/138 (31%), Positives = 53/138 (38%), Gaps = 12/138 (8%)

Query: 51  APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP--PALQPRGAPAV 108
           A +AAH      R    R +A  A      S  P G  G   A+P    P   P   PA 
Sbjct: 34  AASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAG 93

Query: 109 PAAPSPGPLPARPSSPPPR-PSLPSGPHRPVLPPSALAAPRPP----LARPLPQGSVTAR 163
            A P  G  P RP  P PR P +P+GP     PP+A   P P        P+P  +  A 
Sbjct: 94  RARPGGGG-PQRPGPPSPRRPLVPAGP----APPAAKLRPPPEGSAGSCAPVPAAAAVAA 148

Query: 164 EQEQRPRSRRRAGAPEAL 181
             E  P    +   P AL
Sbjct: 149 GPEPAPAGPAKPAGPAAL 166



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 47/136 (34%), Positives = 52/136 (38%), Gaps = 18/136 (13%)

Query: 50  PAPAA-AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAV 108
           PA AA A P AP E            A P     G    GGG    P PP+  PR  P V
Sbjct: 67  PAGAAGAGPAAPAE--------GAPGAAPEPPPAGRARPGGGGPQRPGPPS--PR-RPLV 115

Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA-PRPPLARPLPQGSVTAREQEQ 167
           PA P+P   PA    PPP  S  +G   PV   +A+AA P P  A P       A     
Sbjct: 116 PAGPAP---PAAKLRPPPEGS--AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170

Query: 168 RPRSRRRAGAPEALGP 183
            P      G     GP
Sbjct: 171 GPGPGPGPGPGPGPGP 186



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 52/171 (30%), Positives = 60/171 (35%), Gaps = 21/171 (12%)

Query: 36  PGPALVVAGLDGIRPAPAA-AHPP---------APRERPAAARL---SALAAAQPRRRSP 82
           P PA   A      PAPA  A PP         AP   P AA     SA AA  P   + 
Sbjct: 261 PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320

Query: 83  GPQG-----GGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRP 137
           GP G     G G   A+P P          V AAP      A         S+  GP   
Sbjct: 321 GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQ 380

Query: 138 VLPPSALAAPRPPLARP--LPQGSVTAREQE-QRPRSRRRAGAPEALGPAL 185
              PS  A P P    P  LP+G+  A  Q   R  +   +G    L P +
Sbjct: 381 GALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTV 431



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 48/162 (29%), Positives = 59/162 (36%), Gaps = 20/162 (12%)

Query: 32  GFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGD 91
           G  +  P  V A       AP+    PAP   PAAA      A     R PG   G    
Sbjct: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAP-AAPAAAPPPPPPAPATLARPPGHPAGPPTA 293

Query: 92  IASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPL 151
             +  PPA    G  A  AAP+P P    P+    +P           P +A AAP P +
Sbjct: 294 APAVPPPAAAQNGGSA-GAAPAPAPAAGGPAGVSGQPG----------PGAAAAAPAPGV 342

Query: 152 ARPLPQGSVTAREQEQRPRSRRRAGAPEALGPALTRIHNVEG 193
               P+  V    Q   P ++  A    A GPA T    V G
Sbjct: 343 KAESPKRVV----QAAPPAAQTLA----ASGPASTAASMVIG 376


>gi|22027541 programmed cell death 7 [Homo sapiens]
          Length = 485

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/99 (36%), Positives = 42/99 (42%), Gaps = 9/99 (9%)

Query: 50  PAPAAAHPPAPRERP------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPR 103
           P P+ A PP   +RP      +A  L    A QPR  +   +GGGG     P+PP   P 
Sbjct: 31  PLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAFYPVPP--PPL 88

Query: 104 GAPAVPAAPSPG-PLPARPSSPPPRPSLPSGPHRPVLPP 141
             P     P PG     RP  PPP P  P  P  P  PP
Sbjct: 89  PPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPP 127



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 31/106 (29%), Positives = 35/106 (33%), Gaps = 14/106 (13%)

Query: 76  QPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLP---- 131
           Q R   P PQ         P PP   P   P +P  P P P  + P   PP    P    
Sbjct: 9   QGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASA 68

Query: 132 --------SGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRP 169
                   +G   PV PP     P PP  RP P      R +   P
Sbjct: 69  EASRGGGGAGAFYPVPPPP--LPPPPPQCRPFPGTDAGERPRPPPP 112



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 3/79 (3%)

Query: 99  ALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQG 158
           AL P      P  P P P P  P   PP P LPS    P LP      P P  + P  Q 
Sbjct: 2   ALPPFFGQGRPGPPPPQPPPPAPFGCPP-PPLPSPAFPPPLPQR--PGPFPGASAPFLQP 58

Query: 159 SVTAREQEQRPRSRRRAGA 177
            +  + +     SR   GA
Sbjct: 59  PLALQPRASAEASRGGGGA 77



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 2/67 (2%)

Query: 120 RPSSPPPRPSLPS--GPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGA 177
           RP  PPP+P  P+  G   P LP  A   P P    P P  S    +     + R  A A
Sbjct: 11  RPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEA 70

Query: 178 PEALGPA 184
               G A
Sbjct: 71  SRGGGGA 77


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 64/201 (31%), Positives = 79/201 (39%), Gaps = 31/201 (15%)

Query: 9   RFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPP-----APRE- 62
           RF  A  G GA RR    +  P G   P P  + +     RPAPA   PP     AP   
Sbjct: 365 RFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG 424

Query: 63  ---RPAAARLSALAAAQPRRRSPGPQGGGGGD----IASPLPP-------ALQPRGAPAV 108
              RP    L  L    P    P  Q          +A PL P       AL P  APA+
Sbjct: 425 EPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPAL 484

Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQR 168
           P A +    PA   SP P P++ + P  PV  P+  AAP     R   +GS  AR   ++
Sbjct: 485 PPALAADQAPA--PSPAPAPTV-AEPSPPVSAPAPAAAPIKTRTR-RNKGSRAARGATRK 540

Query: 169 -------PRSRRRAGAPEALG 182
                  PR R  A  P++ G
Sbjct: 541 DGLHGDGPRERATATVPDSSG 561



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 47/153 (30%), Positives = 55/153 (35%), Gaps = 21/153 (13%)

Query: 38  PALVVAGLDGIRPAPAAAHPPAPR--ERPAAARLSALAAAQPRRRSPGPQGGGGGDIAS- 94
           P    A +    PAPA    P P   ++PA   +  +      RR       G GD  S 
Sbjct: 86  PPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRI------RRLLEASHRGQGDPPSL 139

Query: 95  ----PLPPALQPRGAPAVPAAPSPGPLPARP-SSPPPRPSLPSGPHRPVLPPSALAAPRP 149
               P PP  Q      VP APS  P P      PPP PS      R + P  ALA P  
Sbjct: 140 RPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITP--ALATPAS 197

Query: 150 PLARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182
           P     P  S      + +   R R GAP   G
Sbjct: 198 P-----PTESQAGPRNQGQTAGRARGGAPPHAG 225



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 30/107 (28%), Positives = 39/107 (36%), Gaps = 19/107 (17%)

Query: 52  PAAAHPPA---PRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAV 108
           P +A PP    PRE  A+     L   +P    P P+      +++P P       APA 
Sbjct: 52  PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAA--VSAPPP-------APAG 102

Query: 109 PAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPL 155
              P P        +P PR        R +L  S      PP  RPL
Sbjct: 103 TLLPGPSKWQKPAGTPVPRI-------RRLLEASHRGQGDPPSLRPL 142



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 36/124 (29%), Positives = 43/124 (34%), Gaps = 10/124 (8%)

Query: 64  PAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSS 123
           P AAR      ++  + + G  G G G    P  PA Q R  P  P    PG  P     
Sbjct: 296 PGAARPLG-EVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKF--- 351

Query: 124 PPPRPSLPSGPHRPVLPPSA---LAAP-RPPLARPLPQGSVTAREQEQRPRSRRRAGAPE 179
                S P GP R      A   + AP R   A   P GS     ++       R  AP 
Sbjct: 352 --DWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPA 409

Query: 180 ALGP 183
            L P
Sbjct: 410 LLAP 413



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 17/93 (18%)

Query: 104 GAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPP----SALAAPRPPLARPL---- 155
           G+   P    P    A PS+ P     PS    PV+PP    +A++AP P  A  L    
Sbjct: 53  GSATPPGLMVPREPQASPSTLPLTLERPS----PVMPPPEEAAAVSAPPPAPAGTLLPGP 108

Query: 156 -----PQGSVTAREQEQRPRSRRRAGAPEALGP 183
                P G+   R +     S R  G P +L P
Sbjct: 109 SKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRP 141


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/160 (35%), Positives = 64/160 (40%), Gaps = 28/160 (17%)

Query: 16  GGGAGRRVRVGVG----EPGGFCLP---GPALVVAGLDGIRPAPAAAHPPAPRERPAAAR 68
           GGG  RR  +       E    CLP   G A  VAG  G  PA    HPP       A R
Sbjct: 687 GGGPSRRGPLPCPLCSREGACSCLPLERGDA--VAGWGG-HPALGCPHPPEDDSSLRAER 743

Query: 69  --LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPP 126
             L+ L  A P               AS  P  L P    A P  P  GP PA P  PPP
Sbjct: 744 GSLADLPMAPP---------------ASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPP 788

Query: 127 RPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQE 166
            P  P+ P     PPSA+A+P   L+ P P+   +  E E
Sbjct: 789 -PRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETE 827



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 44/142 (30%), Positives = 50/142 (35%), Gaps = 30/142 (21%)

Query: 6    QAARFGAAVRGGGAGR-------RVRVGVGE-PGGFCLPGPALVVAGLDGIRPAPAAAHP 57
            +A   G A R  GAGR       R  VG G  PGG    G       +D  RP P    P
Sbjct: 1120 RAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQP----P 1175

Query: 58   PAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPL 117
            P P   P  A        QPRR  P P             P + P G P  P + + G  
Sbjct: 1176 PPPLPPPPEA--------QPRRLEPAPPRAR---------PEVAPEGEPGAPDSRAGGDT 1218

Query: 118  PARPSSPPPRPSLPSGPHRPVL 139
                   PP+P    GP  P L
Sbjct: 1219 ALSGDGDPPKPE-RKGPEMPRL 1239



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 56/210 (26%), Positives = 68/210 (32%), Gaps = 37/210 (17%)

Query: 13  AVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLS-- 70
           A RG  A   +      P  F  P          G  P PA   PP P   PA    S  
Sbjct: 741 AERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPD 800

Query: 71  ---ALAAAQPRRRSPGPQGGGGG-DIASPL----------------------PPALQPRG 104
              A+A+      SPGP+ G  G +  +P                       PP     G
Sbjct: 801 PPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPG 860

Query: 105 APAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTARE 164
           AP  P  P PGPLP     P  +P+        V     L + R  + R L  G   A  
Sbjct: 861 APRPP--PDPGPLPL--PGPREKPTFVV----QVSTEQLLMSLREDVTRNL-LGEKGATA 911

Query: 165 QEQRPRSRRRAGAPEALGPALTRIHNVEGS 194
           +E  PR   R        P L R   V G+
Sbjct: 912 RETGPRKAGRGPGNREKVPGLNRDPTVLGN 941



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 45/168 (26%), Positives = 57/168 (33%), Gaps = 28/168 (16%)

Query: 36   PGPALVVAGLDGIRPAPAAAHPPAPRE---RPAAARLSALAAAQPRRRSPGPQGGGGGDI 92
            P P+ VV+  +G   AP    P AP+     P   R +      PR    G    G G  
Sbjct: 1085 PAPSAVVSSRNGGETAPGPLGP-APKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGR 1143

Query: 93   ASPLPPALQPRGAPA------------VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLP 140
            A P+     P G P                 P P PLP  P + P R        RP + 
Sbjct: 1144 A-PVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVA 1202

Query: 141  PSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPALTRI 188
            P     P  P +R    G  TA   +  P        PE  GP + R+
Sbjct: 1203 PE--GEPGAPDSR---AGGDTALSGDGDPPK------PERKGPEMPRL 1239



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 117 LPARPSSPPPRPSLPSGPHRPVLPPSALAAPRP-PLARPLP 156
           L  RP  PPP P  P     P   P A +APRP  L+ P P
Sbjct: 441 LSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFP 481



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 60  PRERPAAA----RLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG 115
           P +RP+A+    +L+ L + +P R  P P     G    P PPA     AP      SP 
Sbjct: 424 PAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPA---HSAPRPGTLSSPF 480

Query: 116 PL 117
           PL
Sbjct: 481 PL 482


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 48/159 (30%), Positives = 64/159 (40%), Gaps = 19/159 (11%)

Query: 36  PGPALVVAGLDGIRPAPAAAHPPAPRER-PAAARLSALAAAQPRRRSPGPQGGGGGDIAS 94
           PGP+   AG  G  PA + +  P PR   PA    +   +  P  R  GP G    +  S
Sbjct: 522 PGPS--PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 579

Query: 95  PLP---PALQPRGAPAVPAAPSPGPLPARPS----------SPPPRPSLPSGPHRPVLPP 141
             P   PA   R  PA   + +PGP PA P+          +P PRP+ P+G   P   P
Sbjct: 580 ETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAG-DEPAESP 638

Query: 142 SALAAPRP--PLARPLPQGSVTAREQEQRPRSRRRAGAP 178
           S    P P  P      +    A  Q+    S  ++G P
Sbjct: 639 SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 57/188 (30%), Positives = 69/188 (36%), Gaps = 16/188 (8%)

Query: 6   QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPAL--VVAGLDGIRPAPAAAHPPAPRER 63
           + A   AAV  GGA      G   P G    G +   V    +G R  P    P +P E 
Sbjct: 463 EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEG-RTGPKEGTPGSPSET 521

Query: 64  PAAARLSALA--AAQPRRRSPGPQ-GGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120
           P  +         A+    +PGP+  G  GD      PA  P   P    A   G  PA 
Sbjct: 522 PGPSPAGPAGDEPAESPSETPGPRPAGPAGD-----EPAESPSETPGPRPAGPAGDEPAE 576

Query: 121 PSSPPPRPSLPSGPHR--PVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178
             S  P PS P+GP R  P   PS    PRP  A P       +  +   PR    AG  
Sbjct: 577 SPSETPGPS-PAGPTRDEPAESPSETPGPRP--AGPAGDEPAESPSETPGPRPAGPAGDE 633

Query: 179 EALGPALT 186
            A  P+ T
Sbjct: 634 PAESPSET 641



 Score = 36.2 bits (82), Expect = 0.034
 Identities = 37/112 (33%), Positives = 43/112 (38%), Gaps = 11/112 (9%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAPAAAHPPA--PRERPAAARLSALA--AAQPRRRSPGPQ 85
           P G     PA   +   G RPA  A   PA  P E P  +         A+    +PGP+
Sbjct: 546 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605

Query: 86  -GGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHR 136
             G  GD      PA  P   P    A   G  PA   S  P PS P+GP R
Sbjct: 606 PAGPAGD-----EPAESPSETPGPRPAGPAGDEPAESPSETPGPS-PAGPTR 651


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 46/137 (33%), Positives = 51/137 (37%), Gaps = 14/137 (10%)

Query: 15  RGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAA 74
           RG G     R  V  P     P PA  +    G  P P  A PPAP   P       +  
Sbjct: 282 RGSGLAGPKRSSVVSPSH---PPPAPPLGSPPG--PKPGFAPPPAPPPPPPPM----IGI 332

Query: 75  AQPRRRSPGPQG-GGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSG 133
             P    P P G G  G    P PP+  P    A P  P P P    P+ PPP  S P+G
Sbjct: 333 PPP----PPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTG 388

Query: 134 PHRPVLPPSALAAPRPP 150
              P  PP     P PP
Sbjct: 389 GAPPPPPPPPPPGPPPP 405



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 43/139 (30%), Positives = 54/139 (38%), Gaps = 28/139 (20%)

Query: 46  DGIRPAPAAAHPPAPRERP---AAARLSALAA------AQPRRRSPGPQGGGGGDIASPL 96
           D + P PA    P   +R    A  + S++ +      A P    PGP+ G     A P 
Sbjct: 265 DNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPP 324

Query: 97  PP----ALQPR------GAPAVPAAPSPGPLPARP---SSPPPRPSLPSGPHRPVLPPSA 143
           PP     + P       G+P  P  PSP   P  P   + PPP P  P     P LPP  
Sbjct: 325 PPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPP--PPAADYPTLPPPP 382

Query: 144 LAAPR----PPLARPLPQG 158
           L+ P     PP   P P G
Sbjct: 383 LSQPTGGAPPPPPPPPPPG 401


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 55/197 (27%), Positives = 72/197 (36%), Gaps = 40/197 (20%)

Query: 16  GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAA 75
           GG  G      +G  GG    G A  V G +G        HPP     P +   S  + A
Sbjct: 222 GGTGGVLSGPPMGPKGG----GAASSVGGPNG-----GKQHPPPTT--PISVSSSGASGA 270

Query: 76  QPRRRSPGPQGGGGGDIASPL------------PPALQP-----RGAPAVPAAPSPGPLP 118
            P +    P GGG    A P             PPAL+P        P + A P PG LP
Sbjct: 271 PPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLP 330

Query: 119 AR----------PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQR 168
           +           P  P   P+L   PH   LPP++ +AP PP+  P    S ++      
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSS 388

Query: 169 PRSRRRAGAPEALGPAL 185
             S   + +P     AL
Sbjct: 389 SSSSSSSASPFPASQAL 405



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 7/158 (4%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQ--PRRRSPGPQGG 87
           P G   P P L   G  G+   P    P  P+   AA+ +      +  P   +P     
Sbjct: 209 PPGAPPPHPQLYPGGTGGVLSGP----PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264

Query: 88  GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAP 147
            G   A P  P   P G   +P+AP P   P    + PP P+L    +    PP   A P
Sbjct: 265 SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP 324

Query: 148 RP-PLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPA 184
            P  L  P   G           +    A +P +L PA
Sbjct: 325 LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 37/130 (28%), Positives = 49/130 (37%), Gaps = 17/130 (13%)

Query: 55  AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA-----VP 109
           A PP P   P   + +    A      PG + G      +  PP  +    PA      P
Sbjct: 631 ASPPGP---PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP 687

Query: 110 AAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPL-ARPLPQGSVTAREQEQR 168
            +P+ GP P  P+ P   PSLP        PP A  A  PPL A  + Q      E  + 
Sbjct: 688 GSPTVGPGPLPPAGPSGLPSLP--------PPPAAPASGPPLSATQIKQEPAEEYETPES 739

Query: 169 PRSRRRAGAP 178
           P    R+ +P
Sbjct: 740 PVPPARSPSP 749



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 32/128 (25%)

Query: 59  APRERPAAARLSALAAAQPRRRSPGPQ---GGGGGDIASPLPPALQPRGAPAV------- 108
           AP E P +    A   A P    P PQ   GG GG ++ P    + P+G  A        
Sbjct: 196 APMEPPTSRMFQAPPGAPP----PHPQLYPGGTGGVLSGP---PMGPKGGGAASSVGGPN 248

Query: 109 -------PAAP----SPGPLPARPSSPPPRP----SLPSGPHRPVLPPSALAAPRPPLAR 153
                  P  P    S G   A P+ PP  P    +LPS P     P      P PP  R
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR 308

Query: 154 PLPQGSVT 161
           PL   S +
Sbjct: 309 PLNNASAS 316



 Score = 35.0 bits (79), Expect = 0.075
 Identities = 53/179 (29%), Positives = 66/179 (36%), Gaps = 20/179 (11%)

Query: 2   PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCL-PGPALVVAGLDGIRPAPAAAHPPAP 60
           PG   + R G      G       G  +PG   + PGP L  AG  G+   P    P AP
Sbjct: 659 PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP-LPPAGPSGLPSLPPP--PAAP 715

Query: 61  RERPAAARLSALAAAQ-PRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPA 119
              P    LSA    Q P      P+        SP+PPA  P   P V   PS     A
Sbjct: 716 ASGPP---LSATQIKQEPAEEYETPE--------SPVPPARSPSPPPKVVDVPSHASQSA 764

Query: 120 RPSSPPPR---PSLPSGPHRPVLPPSALAAPRPPLARPL-PQGSVTAREQEQRPRSRRR 174
           R +    R       S  +   L  S LA  R  L   +  +    ARE+++R R R R
Sbjct: 765 RFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERERER 823



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 25/119 (21%)

Query: 35  LPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIAS 94
           LP P  +  G+ G+        PP P + P  A              P P        ++
Sbjct: 329 LPSPHAMGQGMGGL--------PPGPEKGPTLA--------------PSPHSLPPASSSA 366

Query: 95  PLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP---SLPSGPHRPVLPPSALAAPRPP 150
           P PP   P  + +  +A +     +  SS  P P   +LPS PH    P S   + +PP
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 11/86 (12%)

Query: 80  RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSP--GPLPARPSSPP--------PRPS 129
           RS  P     G + +    +      PA P  P P   P P  P S P        P PS
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPS 188

Query: 130 L-PSGPHRPVLPPSALAAPRPPLARP 154
           + P+G H P+ PP++     PP A P
Sbjct: 189 VTPTGYHAPMEPPTSRMFQAPPGAPP 214



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 37/136 (27%), Positives = 50/136 (36%), Gaps = 30/136 (22%)

Query: 57  PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116
           PP P    ++A LS + A      SP      G   ASP  P    + AP+  A  +  P
Sbjct: 602 PPVPTVTTSSATLSTVIATVAS--SPA-----GYKTASPPGPPPYGKRAPSPGAYKTATP 654

Query: 117 LPARPSSPPP----------RPSLPSGPHR-------------PVLPPSALAAPRPPLAR 153
              +P SPP             S P+GP               P   PS L +  PP A 
Sbjct: 655 PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714

Query: 154 PLPQGSVTAREQEQRP 169
           P     ++A + +Q P
Sbjct: 715 PASGPPLSATQIKQEP 730



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 98  PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVL--PP 141
           P++ P G  A    P+     A P +PPP P L  G    VL  PP
Sbjct: 187 PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 55/197 (27%), Positives = 72/197 (36%), Gaps = 40/197 (20%)

Query: 16  GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAA 75
           GG  G      +G  GG    G A  V G +G        HPP     P +   S  + A
Sbjct: 222 GGTGGVLSGPPMGPKGG----GAASSVGGPNG-----GKQHPPPTT--PISVSSSGASGA 270

Query: 76  QPRRRSPGPQGGGGGDIASPL------------PPALQP-----RGAPAVPAAPSPGPLP 118
            P +    P GGG    A P             PPAL+P        P + A P PG LP
Sbjct: 271 PPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLP 330

Query: 119 AR----------PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQR 168
           +           P  P   P+L   PH   LPP++ +AP PP+  P    S ++      
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSS 388

Query: 169 PRSRRRAGAPEALGPAL 185
             S   + +P     AL
Sbjct: 389 SSSSSSSASPFPASQAL 405



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 7/158 (4%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQ--PRRRSPGPQGG 87
           P G   P P L   G  G+   P    P  P+   AA+ +      +  P   +P     
Sbjct: 209 PPGAPPPHPQLYPGGTGGVLSGP----PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264

Query: 88  GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAP 147
            G   A P  P   P G   +P+AP P   P    + PP P+L    +    PP   A P
Sbjct: 265 SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP 324

Query: 148 RP-PLARPLPQGSVTAREQEQRPRSRRRAGAPEALGPA 184
            P  L  P   G           +    A +P +L PA
Sbjct: 325 LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 37/130 (28%), Positives = 49/130 (37%), Gaps = 17/130 (13%)

Query: 55  AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA-----VP 109
           A PP P   P   + +    A      PG + G      +  PP  +    PA      P
Sbjct: 631 ASPPGP---PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP 687

Query: 110 AAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPL-ARPLPQGSVTAREQEQR 168
            +P+ GP P  P+ P   PSLP        PP A  A  PPL A  + Q      E  + 
Sbjct: 688 GSPTVGPGPLPPAGPSGLPSLP--------PPPAAPASGPPLSATQIKQEPAEEYETPES 739

Query: 169 PRSRRRAGAP 178
           P    R+ +P
Sbjct: 740 PVPPARSPSP 749



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 32/128 (25%)

Query: 59  APRERPAAARLSALAAAQPRRRSPGPQ---GGGGGDIASPLPPALQPRGAPAV------- 108
           AP E P +    A   A P    P PQ   GG GG ++ P    + P+G  A        
Sbjct: 196 APMEPPTSRMFQAPPGAPP----PHPQLYPGGTGGVLSGP---PMGPKGGGAASSVGGPN 248

Query: 109 -------PAAP----SPGPLPARPSSPPPRP----SLPSGPHRPVLPPSALAAPRPPLAR 153
                  P  P    S G   A P+ PP  P    +LPS P     P      P PP  R
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR 308

Query: 154 PLPQGSVT 161
           PL   S +
Sbjct: 309 PLNNASAS 316



 Score = 35.0 bits (79), Expect = 0.075
 Identities = 53/179 (29%), Positives = 66/179 (36%), Gaps = 20/179 (11%)

Query: 2   PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCL-PGPALVVAGLDGIRPAPAAAHPPAP 60
           PG   + R G      G       G  +PG   + PGP L  AG  G+   P    P AP
Sbjct: 659 PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP-LPPAGPSGLPSLPPP--PAAP 715

Query: 61  RERPAAARLSALAAAQ-PRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPA 119
              P    LSA    Q P      P+        SP+PPA  P   P V   PS     A
Sbjct: 716 ASGPP---LSATQIKQEPAEEYETPE--------SPVPPARSPSPPPKVVDVPSHASQSA 764

Query: 120 RPSSPPPR---PSLPSGPHRPVLPPSALAAPRPPLARPL-PQGSVTAREQEQRPRSRRR 174
           R +    R       S  +   L  S LA  R  L   +  +    ARE+++R R R R
Sbjct: 765 RFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERERER 823



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 25/119 (21%)

Query: 35  LPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIAS 94
           LP P  +  G+ G+        PP P + P  A              P P        ++
Sbjct: 329 LPSPHAMGQGMGGL--------PPGPEKGPTLA--------------PSPHSLPPASSSA 366

Query: 95  PLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP---SLPSGPHRPVLPPSALAAPRPP 150
           P PP   P  + +  +A +     +  SS  P P   +LPS PH    P S   + +PP
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 11/86 (12%)

Query: 80  RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSP--GPLPARPSSPP--------PRPS 129
           RS  P     G + +    +      PA P  P P   P P  P S P        P PS
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPS 188

Query: 130 L-PSGPHRPVLPPSALAAPRPPLARP 154
           + P+G H P+ PP++     PP A P
Sbjct: 189 VTPTGYHAPMEPPTSRMFQAPPGAPP 214



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 37/136 (27%), Positives = 50/136 (36%), Gaps = 30/136 (22%)

Query: 57  PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116
           PP P    ++A LS + A      SP      G   ASP  P    + AP+  A  +  P
Sbjct: 602 PPVPTVTTSSATLSTVIATVAS--SPA-----GYKTASPPGPPPYGKRAPSPGAYKTATP 654

Query: 117 LPARPSSPPP----------RPSLPSGPHR-------------PVLPPSALAAPRPPLAR 153
              +P SPP             S P+GP               P   PS L +  PP A 
Sbjct: 655 PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714

Query: 154 PLPQGSVTAREQEQRP 169
           P     ++A + +Q P
Sbjct: 715 PASGPPLSATQIKQEP 730



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 98  PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVL--PP 141
           P++ P G  A    P+     A P +PPP P L  G    VL  PP
Sbjct: 187 PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 40/113 (35%), Positives = 43/113 (38%), Gaps = 27/113 (23%)

Query: 50  PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109
           P P A+ PP P                     P P G G    A P+PP     G P  P
Sbjct: 646 PPPPASIPPPP---------------------PLPSGLGSLSPAPPMPPV--SAGPPLPP 682

Query: 110 AAPSPGPLP----ARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQG 158
             P P PLP    A P  PPP P LP+ P  P       A P P LA P P G
Sbjct: 683 PPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 39/126 (30%), Positives = 48/126 (38%), Gaps = 29/126 (23%)

Query: 35  LPGPALVVAGLDGIRPAP----AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90
           +P P  + +GL  + PAP     +A PP P   P    L   ++A P    P P      
Sbjct: 652 IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGP----PPP------ 701

Query: 91  DIASPLPPALQPRGAPAVPAAPSPGPLP-ARPSSPPPRPSLPSG--------PHRPVLPP 141
               P PP L    AP  P  P P P P      PPP P L  G        P +P + P
Sbjct: 702 ----PPPPPLPNSPAPPNPGGPPPAPPPPGLA--PPPPPGLFFGLGSSSSQCPRKPAIEP 755

Query: 142 SALAAP 147
           S    P
Sbjct: 756 SCPMKP 761



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 14/86 (16%)

Query: 69  LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP 128
           +  +A+ Q +   P P        AS  PP   P G  ++  AP   P+ A P  PPP P
Sbjct: 634 MEGMASNQQKALPPPP--------ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP 685

Query: 129 SLPSGPHRPVLPPSALAAPRPPLARP 154
             P       LPP + A P PP   P
Sbjct: 686 PPPP------LPPPSSAGPPPPPPPP 705



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 29/73 (39%), Positives = 32/73 (43%), Gaps = 9/73 (12%)

Query: 92  IASPLPPALQPRGAPAVPAAPSPGPL----PARPSSP----PPRPSLPSGPHRPVLPPSA 143
           +AS    AL P  A   P  P P  L    PA P  P    PP P  P  P  P+ PPS+
Sbjct: 637 MASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP-PPPPPPPLPPPSS 695

Query: 144 LAAPRPPLARPLP 156
              P PP   PLP
Sbjct: 696 AGPPPPPPPPPLP 708



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 3/104 (2%)

Query: 30  PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
           P G     PA  +  +    P P    PP P   P++A         P   SP P   GG
Sbjct: 659 PSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718

Query: 90  GDIASPLPPALQPRGAPAV--PAAPSPGPLPARPSSPPPRPSLP 131
              A P PP L P   P +      S    P +P+  P  P  P
Sbjct: 719 PPPAPP-PPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761



 Score = 34.7 bits (78), Expect = 0.098
 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%)

Query: 101 QPRGAPAVPAA-PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGS 159
           Q +  P  PA+ P P PLP+   S  P P +P     P LPP       PP   PLP  S
Sbjct: 641 QQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPP------PPPPPPLPPPS 694



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 23/59 (38%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 99  ALQPRGAPAVPAAPSPGPLPARPSSPPPRPS-LPSGPHRPVLPPSALAAPRPPLARPLP 156
           ALQP    A     +  P PA    PPP PS L S    P +PP +   P PP   P P
Sbjct: 630 ALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 47/135 (34%), Positives = 50/135 (37%), Gaps = 13/135 (9%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG   LP P L  AG+    P P AA PP P   P       L    P    P P    G
Sbjct: 927  PGAGILPLPPLPGAGIPPPPPLPGAAIPPPP---PLPGAGIPLPPPLPGAGIPPPPPLPG 983

Query: 90   GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP----PPRPSLPSGPHRPVLPPSALA 145
              I  P PP L   G P  P  P  G +P  P  P    PP P LP     P  P     
Sbjct: 984  AGI--PPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040

Query: 146  APRPPLARPLPQGSV 160
             P PP   PLP   +
Sbjct: 1041 IPPPP---PLPGAGI 1052



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 46/134 (34%), Positives = 50/134 (37%), Gaps = 22/134 (16%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+  + P P A  PP P   P        AA  P    P P  G G
Sbjct: 916  PGAGIPPPPPLPGAGILPLPPLPGAGIPPPP---PLPG-----AAIPP----PPPLPGAG 963

Query: 90   GDIASPLPPALQPRGAPAVPAAPS---PGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146
                 PLPP L   G P  P  P    P P P   +  PP P LP     P  P      
Sbjct: 964  ----IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019

Query: 147  PRPPLARPLPQGSV 160
            P PP   PLP   +
Sbjct: 1020 PPPP---PLPGAGI 1030



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 43/131 (32%), Positives = 48/131 (36%), Gaps = 5/131 (3%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P A  PP P   P A               P P  G G
Sbjct: 993  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051

Query: 90   GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRP 149
                 PLP A  P   P +P A  P P P   +  PP P LP     P  P   +  P P
Sbjct: 1052 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110

Query: 150  PLARPLPQGSV 160
            P   PLP   +
Sbjct: 1111 P---PLPGAGI 1118



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 46/140 (32%), Positives = 51/140 (36%), Gaps = 18/140 (12%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P A  PP P   P            P    P P    G
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1071

Query: 90   GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP----PPRPSLPSG--PHRPVLPPSA 143
              I  P PP L   G P  P  P  G +P  P  P    PP P LP    P  P LP + 
Sbjct: 1072 AGI--PPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128

Query: 144  LAAPRP------PLARPLPQ 157
            +  P P      P   PLP+
Sbjct: 1129 IPPPPPLPGAGIPPPPPLPR 1148



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 45/124 (36%), Positives = 48/124 (38%), Gaps = 5/124 (4%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P A  PP P   P A               P P  G G
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117

Query: 90   GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAP 147
                 PLP A  P   P +P A  P P PLP R   PPP P   +G   P   P A   P
Sbjct: 1118 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP-RVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175

Query: 148  RPPL 151
             PPL
Sbjct: 1176 PPPL 1179



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 43/134 (32%), Positives = 46/134 (34%), Gaps = 11/134 (8%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P A  PP P   P            P    P P    G
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1060

Query: 90   GDIASPLPPALQPRGAPAVPAAPS---PGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146
              I  P PP L   G P  P  P    P P P   +  PP P LP     P  P      
Sbjct: 1061 AGI--PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118

Query: 147  PRPPLARPLPQGSV 160
            P PP   PLP   +
Sbjct: 1119 PPPP---PLPGAGI 1129



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 47/136 (34%), Positives = 51/136 (37%), Gaps = 11/136 (8%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P    PP P   P            P    P P    G
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1181

Query: 90   GDIASPLP-PALQPRGAPAVPAA--PSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAA 146
              I  P P P +     P +P A  P P PLP     P P P LP  P   + PP  L  
Sbjct: 1182 VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP-PGTGIPPPPLLPV 1240

Query: 147  PRPPLARPLPQ-GSVT 161
              PPL   LPQ GS T
Sbjct: 1241 SGPPL---LPQVGSST 1253



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 44/138 (31%), Positives = 48/138 (34%), Gaps = 16/138 (11%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P A  PP P   P            P    P P    G
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1104

Query: 90   GDIASPLPPALQPRGAPAVP-----AAPSPGPLPAR---PSSPPPRPSLPSGPHRP---V 138
              +  P PP L   G P  P       P P PLP     P  P PR  +P  P  P   +
Sbjct: 1105 --VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162

Query: 139  LPPSALAAPRPPLARPLP 156
             PP  L     P   PLP
Sbjct: 1163 PPPPPLPGAGIPPPPPLP 1180



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 43/135 (31%), Positives = 47/135 (34%), Gaps = 13/135 (9%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P    PP P   P            P    P P    G
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1137

Query: 90   GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP----PPRPSLPSGPHRPVLPPSALA 145
              I  P PP L   G P  P  P  G +P  P  P    PP P LP     P  P   + 
Sbjct: 1138 AGI--PPPPPLPRVGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194

Query: 146  APRPPLARPLPQGSV 160
             P PP   PLP   +
Sbjct: 1195 IPPPP---PLPGAGI 1206



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 33/107 (30%), Positives = 37/107 (34%), Gaps = 11/107 (10%)

Query: 57  PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116
           PP P   P            P    P P    G ++  P PP L   G P  P  P  G 
Sbjct: 877 PPPPPPLPGMT-----VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931

Query: 117 LPARP---SSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSV 160
           LP  P   +  PP P LP     P  P      P PP   PLP   +
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP---PLPGAGI 975



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 42/134 (31%), Positives = 46/134 (34%), Gaps = 26/134 (19%)

Query: 30   PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89
            PG    P P L  AG+    P P    PP P                P    P P    G
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP--------------PLPGVGIPPPPPLPG 1203

Query: 90   GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPR- 148
              I  P PP L   G P  PA P P P       PPP   +   P  P +  S L  P+ 
Sbjct: 1204 AGI--PPPPPLPGMGIPPAPAPPLPPP--GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259

Query: 149  ----PPLARPLPQG 158
                PP   PLP G
Sbjct: 1260 CGFLPP---PLPSG 1270



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 2/114 (1%)

Query: 38  PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97
           P  +   LD  +P  + + PP P     +A      +  P   S   Q      ++S   
Sbjct: 791 PRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK 850

Query: 98  PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPL 151
            +      P +P   S   +P     PPP P LP G   P LP +A+  P PPL
Sbjct: 851 NSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP-GMTVPTLPSTAIPQP-PPL 902



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 3/66 (4%)

Query: 89  GGDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPRPSLPSGPHRPVLP-PSALA 145
           G  +  P PP L     P +P+   P P PL      PPP P LP     P  P P A  
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931

Query: 146 APRPPL 151
            P PPL
Sbjct: 932 LPLPPL 937



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 44  GLDGIRPAPAAAHPPAPRERPAAARLSALA------AAQPRRRSPGPQGGGGGDIASPLP 97
           GLD     P+     AP        LSAL+      AA+PR     P  GG     +P  
Sbjct: 248 GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL 307

Query: 98  PALQP--RGAPAVPAAPSPGPLPARPSSPPP 126
           PA QP  + +P+  A P P   P   ++  P
Sbjct: 308 PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 58   PAPRERPAAARLSALAAAQPRRRSPG-PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116
            P     P    L+  AA       PG P     G   +P PP L+ +  P  P AP+P P
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNG---TPEPPLLEEKPPPTPPPAPTPQP 1469

Query: 117  LPARPSSPPPRPSLPSGPHRPVL-------PPSALAAPRPPLARPLPQGSVTAREQEQRP 169
             P  P  PPP+P+LPS P  P++       PP  L  P PP     P     A      P
Sbjct: 1470 QPP-PPPPPPQPALPSPP--PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526

Query: 170  RSRRRAGAPEALGPALTR-IHNVEGSKDSWNCGQ 202
                 A +PE      TR +H  +  + +  CG+
Sbjct: 1527 PEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE 1560



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 5/117 (4%)

Query: 46   DGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA 105
            DG   APAAA P  P      +  S      P      P          P PP   P   
Sbjct: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ 1479

Query: 106  PAVPA-----APSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQ 157
            PA+P+     AP+P   P  P  PPP P++PS P  P    + LAAP    A P P+
Sbjct: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE 1536



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 36/108 (33%), Positives = 44/108 (40%), Gaps = 4/108 (3%)

Query: 36   PGPALVVAGLDGIRPAPAAAH--PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIA 93
            P P L  A  +G    P      PP P   P            P+   P P        +
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS 1494

Query: 94   SPLPPALQPRGAPAVPAAPSPGPLPARP-SSPPPRPSLPSGPHRPVLP 140
            SP PP L P   PA+P+ P P P  A P ++PP  P+ PS P  P LP
Sbjct: 1495 SPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS-PEDPELP 1541



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 45/140 (32%), Positives = 53/140 (37%), Gaps = 25/140 (17%)

Query: 4   GVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRER 63
           G +AA  G A  GGG  R +   +  PG     G     AG         A  PP PR  
Sbjct: 364 GPEAAGGGGAGGGGGGYRPI---IQSPGYKTGKGGYGAAAG--------GATRPPPPRST 412

Query: 64  --PAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPP--ALQPRG---------APAVPA 110
             P    L   AAA    ++ G  GG GG   SP  P   L P+          A  +  
Sbjct: 413 ATPKCQSLGGPAAAYATGKASGA-GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSK 471

Query: 111 APSPGPLPARPSSPPPRPSL 130
           APS    P +P S PP P L
Sbjct: 472 APSYSGGPPQPPSGPPPPGL 491



 Score = 37.4 bits (85), Expect = 0.015
 Identities = 41/154 (26%), Positives = 52/154 (33%), Gaps = 41/154 (26%)

Query: 47   GIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQ------GGGGGDIASPLPPAL 100
            G   +P+     APR  P  +     +  Q   RS  P       GG   D     PP  
Sbjct: 911  GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPP-- 968

Query: 101  QPRGAPAVPAAPSPGP---------LPAR--------------PSSPPPRPS-------- 129
            +  G P   A P PGP          P R              P+ PP  PS        
Sbjct: 969  EDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLG 1028

Query: 130  -LPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162
             + SGPH+   PP     P PP     P+G +T+
Sbjct: 1029 LIQSGPHQ-AAPPPPPPPPPPPAPASEPKGGLTS 1061



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 50/168 (29%), Positives = 55/168 (32%), Gaps = 24/168 (14%)

Query: 31  GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARL---SALAAAQPRRRSPGPQGG 87
           GG  L    L  A     RP P    PP PR  P    L   S+ AAA   + SP     
Sbjct: 210 GGGVLGPAGLGPAQTPPYRPGPPDP-PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF 268

Query: 88  GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRP-----------SLPSGPHR 136
            G     P P    PR    +     P    A+P  PPP             S PS  HR
Sbjct: 269 SGAAPGPPPPERALPRQDTVIKHYQRPA--SAQPPPPPPPAHALQHYLSCGGSYPSMGHR 326

Query: 137 PVLPPSALAA--PRPPLARPLPQGSVTAREQEQRPRSRRRAGAPEALG 182
             L  S L    P P    P   G   A        +  RA  PEA G
Sbjct: 327 ANLACSPLGGGEPSPGAGEPSKAGPSGA-----TAGASGRATGPEAAG 369



 Score = 32.3 bits (72), Expect = 0.49
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 11/79 (13%)

Query: 82  PGPQG----GGGGDIASPLPPALQPRGAPAVPA-APSPGPLPARPSSPPPRPSLPSGPHR 136
           P P G     GG D+   LPP   P+  P+V + APSP P  ++       P+   G  +
Sbjct: 776 PTPHGLLLEAGGPDLPLVLPPP-PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQ 834

Query: 137 PVLPPSALAAPRPPLARPL 155
           P  PP     P PP   PL
Sbjct: 835 PPPPP-----PPPPPPMPL 848



 Score = 32.0 bits (71), Expect = 0.64
 Identities = 32/108 (29%), Positives = 41/108 (37%), Gaps = 2/108 (1%)

Query: 98   PALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQ 157
            PAL P G       P+PGP   R     P  +   GP RP   P       P  A P   
Sbjct: 1132 PALSPLGDIDF-CPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASA 1190

Query: 158  GSVTAREQEQRPRSRRRA-GAPEALGPALTRIHNVEGSKDSWNCGQGL 204
             + T   ++ R R R R   A EA G  L  +  ++        G+GL
Sbjct: 1191 STPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGL 1238



 Score = 31.6 bits (70), Expect = 0.83
 Identities = 34/133 (25%), Positives = 48/133 (36%), Gaps = 17/133 (12%)

Query: 57   PPAPRERPAAARLSALA----AAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112
            PP P  R   A+    A    A  P+  +P P+        S  PP   P  A   P AP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729

Query: 113  SPGPLPARPSSPPPRPSLPSGPHRPV-----------LPPSALAAPRPPLARPLPQGSVT 161
               P   RP          +   RP+            P  +LA  +P  +R LP+   T
Sbjct: 1730 EK-PSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSR-LPKARPT 1787

Query: 162  AREQEQRPRSRRR 174
              + E  P+ R++
Sbjct: 1788 KVKAEPPPKKRKK 1800



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 2/96 (2%)

Query: 40  LVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPA 99
           L  + L G  P+P A  P       A A  S  A         G  GGGGG       P 
Sbjct: 329 LACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPG 388

Query: 100 LQP-RGAPAVPAAPSPGPLPARPSSPPPRPSLPSGP 134
            +  +G     A  +  P P R ++ P   SL  GP
Sbjct: 389 YKTGKGGYGAAAGGATRPPPPRSTATPKCQSL-GGP 423



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 13/101 (12%)

Query: 95   PLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLP--SGPHRPVLPPSALAAPRPP-- 150
            P+P     +    V A  S  P P  P+ PPP+P  P  +   +P       A P PP  
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPA-PPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729

Query: 151  ----LARPLPQGSVTAREQEQRPRSRRRAGAPEALGPALTR 187
                L RP+ +     +E+E+  R  R      A     TR
Sbjct: 1730 EKPSLLRPVEK----EKEKEKVTRGERPLRGERATSGRQTR 1766



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 24/126 (19%)

Query: 55  AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP-------RGAPA 107
           +H P+P   P+A+++  +   +P  R   PQ         P PP   P       R    
Sbjct: 807 SHAPSPS--PSASKVG-VHLLEPATRDGAPQPPP----PPPPPPPPMPLQLEAHLRSHGL 859

Query: 108 VPAAPSPGPLPARPSSPPPRPSLPSGPHRPVLPPSALAAPRPPLAR----------PLPQ 157
            PAAPSP   P     PP       G   P+ P        PP +           P PQ
Sbjct: 860 EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ 919

Query: 158 GSVTAR 163
           G+   R
Sbjct: 920 GTKAPR 925



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 20/83 (24%)

Query: 83   GPQGGGGGDIASPLPPAL--QPRGAPAVPAAPSP--------GPLPARPSSPPPRPSLPS 132
            GP   G    A P  P L   P   P +P+  +         GP  A P  PPP P    
Sbjct: 991  GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPP--- 1047

Query: 133  GPHRPVLPPSALAAPRPPLARPL 155
                   PP+  + P+  L  P+
Sbjct: 1048 -------PPAPASEPKGGLTSPI 1063


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,375,559
Number of Sequences: 37866
Number of extensions: 1352843
Number of successful extensions: 36966
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1122
Number of HSP's successfully gapped in prelim test: 2503
Number of HSP's that attempted gapping in prelim test: 11414
Number of HSP's gapped (non-prelim): 14034
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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