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Search of human proteins with 239742474
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239742474 PREDICTED: hypothetical protein [Homo sapiens]
(589 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239742474 PREDICTED: hypothetical protein [Homo sapiens] 1230 0.0
gi|57864582 hornerin [Homo sapiens] 54 4e-07
gi|239756601 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06
gi|239751093 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06
gi|239745582 PREDICTED: hypothetical protein XP_002344135 [Homo ... 52 1e-06
gi|60097902 filaggrin [Homo sapiens] 51 3e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 46 8e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 45 1e-04
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 44 3e-04
gi|7706635 cornulin [Homo sapiens] 44 4e-04
gi|62122917 filaggrin family member 2 [Homo sapiens] 42 0.002
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 41 0.003
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi... 41 0.004
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 41 0.004
gi|239751791 PREDICTED: hypothetical protein [Homo sapiens] 40 0.005
gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo ... 40 0.005
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 39 0.010
gi|91208420 bassoon protein [Homo sapiens] 39 0.010
gi|239757898 PREDICTED: similar to testis expressed sequence 13A... 39 0.013
gi|239752412 PREDICTED: similar to testis expressed sequence 13A... 39 0.013
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 39 0.013
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens] 39 0.017
gi|169216868 PREDICTED: similar to testis expressed sequence 13A... 39 0.017
gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo ... 38 0.023
gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo ... 38 0.023
gi|239508758 PREDICTED: hypothetical protein [Homo sapiens] 38 0.023
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 38 0.023
gi|239749325 PREDICTED: hypothetical protein [Homo sapiens] 38 0.030
gi|239509122 PREDICTED: hypothetical protein [Homo sapiens] 38 0.030
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 38 0.030
>gi|239742474 PREDICTED: hypothetical protein [Homo sapiens]
Length = 589
Score = 1230 bits (3183), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MLAGSSALGLLLCSGRGSPSTELWPQQVHSWESGRRVVLMRASEGGASPPSCTVSLALGS 60
MLAGSSALGLLLCSGRGSPSTELWPQQVHSWESGRRVVLMRASEGGASPPSCTVSLALGS
Sbjct: 1 MLAGSSALGLLLCSGRGSPSTELWPQQVHSWESGRRVVLMRASEGGASPPSCTVSLALGS 60
Query: 61 PLPWPEPDRSHGLTGSGKVSPGLPQAHPQVDSRTTAQQVTRVAVAVSTRPALPLPLPEGS 120
PLPWPEPDRSHGLTGSGKVSPGLPQAHPQVDSRTTAQQVTRVAVAVSTRPALPLPLPEGS
Sbjct: 61 PLPWPEPDRSHGLTGSGKVSPGLPQAHPQVDSRTTAQQVTRVAVAVSTRPALPLPLPEGS 120
Query: 121 KRSLWEPVNLVVSVSLDTVGDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAH 180
KRSLWEPVNLVVSVSLDTVGDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAH
Sbjct: 121 KRSLWEPVNLVVSVSLDTVGDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAH 180
Query: 181 GEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVRE 240
GEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVRE
Sbjct: 181 GEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVRE 240
Query: 241 VPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRG 300
VPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRG
Sbjct: 241 VPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRG 300
Query: 301 RRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQ 360
RRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQ
Sbjct: 301 RRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQ 360
Query: 361 SALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAE 420
SALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAE
Sbjct: 361 SALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAE 420
Query: 421 GSHAGHIPDPPAIGRCCPAASPRGRWLWTWRPHCEPHLLLRGLNIADPVSLSRSECPGHV 480
GSHAGHIPDPPAIGRCCPAASPRGRWLWTWRPHCEPHLLLRGLNIADPVSLSRSECPGHV
Sbjct: 421 GSHAGHIPDPPAIGRCCPAASPRGRWLWTWRPHCEPHLLLRGLNIADPVSLSRSECPGHV 480
Query: 481 PLAEAALVTRTCQQLAGAIYTGPHRMARCCRRLQAAADISPVDDVGAPASLWELPLAKEP 540
PLAEAALVTRTCQQLAGAIYTGPHRMARCCRRLQAAADISPVDDVGAPASLWELPLAKEP
Sbjct: 481 PLAEAALVTRTCQQLAGAIYTGPHRMARCCRRLQAAADISPVDDVGAPASLWELPLAKEP 540
Query: 541 TSKACTAESGASCFSHSPEGGAALRAPCAFLVSRGPRDEWSWVSVGSNR 589
TSKACTAESGASCFSHSPEGGAALRAPCAFLVSRGPRDEWSWVSVGSNR
Sbjct: 541 TSKACTAESGASCFSHSPEGGAALRAPCAFLVSRGPRDEWSWVSVGSNR 589
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 53.9 bits (128), Expect = 4e-07
Identities = 62/275 (22%), Positives = 95/275 (34%), Gaps = 20/275 (7%)
Query: 177 RQAHGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRV 235
R HG GS + S G Y G RGP++ + + G R R G + + + G
Sbjct: 1951 RGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 2010
Query: 236 GAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTE 295
G G+ + + S+ + G + + + G +G G + H +
Sbjct: 2011 GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2070
Query: 296 RGPRGR------RQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAA 349
RG R R GS G S + H PG ++ H S H S +
Sbjct: 2071 RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQH--GSGSG 2128
Query: 350 EPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGE 409
H S+S R + H S+ + Q +R+ SG G G G
Sbjct: 2129 HSSGYGQHGSRSGQSSRGER------HGSSSGSSSRYGQHGSGSRQSSGH-GRQGSGSGH 2181
Query: 410 TEPQGGAWTAEGSHAGHIPDPPAIGRCCPAASPRG 444
+ +G GS +GH G +S RG
Sbjct: 2182 SPSRG----RHGSGSGHSSSHGQHGSGSGRSSSRG 2212
Score = 53.1 bits (126), Expect = 7e-07
Identities = 63/263 (23%), Positives = 101/263 (38%), Gaps = 27/263 (10%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG S + S G++ + G+ G H + + + G +G G + H +RG
Sbjct: 2489 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG---SGS 2545
Query: 239 REVPTSTQRG---GRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTE 295
R+ P+ + G GR + + + E G + S+ + + G G + + +
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 296 RG------PRGRRQGSADGNHSEAPAHSPG-----GSDNQINCRHLELSRPR-GGGLVHT 343
G RG R GS+ G+ S H G G Q + SR R G GL H+
Sbjct: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
Query: 344 RPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSG-GLAV 402
S+ + S+ + R HS+V H + + ++ GSG G
Sbjct: 2666 -SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGS------GHSSAYSQHGSGSGHFC 2718
Query: 403 SGGGFGETEPQGGAWTAEGSHAG 425
S G G T Q + EGS G
Sbjct: 2719 SQGQHGSTSGQSSTFDQEGSSTG 2741
Score = 52.8 bits (125), Expect = 9e-07
Identities = 62/275 (22%), Positives = 94/275 (34%), Gaps = 20/275 (7%)
Query: 177 RQAHGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRV 235
R HG GS + S G YR G RGP++ + + G R R G + + + G
Sbjct: 1011 RGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 1070
Query: 236 GAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTE 295
G G+ + + S+ + G + + + G +G G + H +
Sbjct: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1130
Query: 296 RGPRGR------RQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAA 349
RG R R GS G S + H G ++ H S H S +
Sbjct: 1131 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH--GSGSG 1188
Query: 350 EPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGE 409
H S+S R + H S+ + Q +R+ SG G G G
Sbjct: 1189 HSSGYGQHGSRSGQSSRGER------HGSSSGSSSHYGQHGSGSRQSSGH-GRQGSGSGH 1241
Query: 410 TEPQGGAWTAEGSHAGHIPDPPAIGRCCPAASPRG 444
+ +G GS GH G +S RG
Sbjct: 1242 SPSRG----RHGSGLGHSSSHGQHGSGSGRSSSRG 1272
Score = 51.2 bits (121), Expect = 3e-06
Identities = 66/307 (21%), Positives = 107/307 (34%), Gaps = 25/307 (8%)
Query: 149 SRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPS---GKYRQAHGEGGPRGPH 205
SR + G + Y + + HG GS +PS G++ + GPH
Sbjct: 502 SRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPH 561
Query: 206 QGSTDKHTERGP----RGPRQGSTDKHTERGVRVGAVREVPTS--TQRGGRVGAVREVRT 259
+ + + RGP G G + + G G + +S + G+ G+ +
Sbjct: 562 GYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 621
Query: 260 STLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAHSPG 319
S + G + S +H + R G + + P R GS G+ S H G
Sbjct: 622 SCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSG 681
Query: 320 GSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDS 379
+ N H +S G S + + + H S S+ HS+ H
Sbjct: 682 SGWSSSNGPHGSVSGQSSG---FGHKSGSGQSSGYSQHGSGSS------HSSGYRKHGSR 732
Query: 380 TPTPREQAQDTHPTREGSG-GLAVSGGGFGETEPQGGAWTAEGSHAGHIPDPPAIGRCCP 438
+ Q + + GS GL+ S G G Q +GS +GH P G
Sbjct: 733 S------GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSG 786
Query: 439 AASPRGR 445
+S G+
Sbjct: 787 HSSSHGQ 793
Score = 50.8 bits (120), Expect = 3e-06
Identities = 62/263 (23%), Positives = 100/263 (38%), Gaps = 27/263 (10%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG S + S G++ + G+ G H + + + G +G G + H +RG
Sbjct: 1549 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG---SGS 1605
Query: 239 REVPTSTQRG---GRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTE 295
R+ P+ + G GR + + + E G + S+ + + G G + + +
Sbjct: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
Query: 296 RG------PRGRRQGSADGNHSEAPAHSPG-----GSDNQINCRHLELSRPR-GGGLVHT 343
G RG R GS+ + S H G G Q + SR R G GL H+
Sbjct: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 1725
Query: 344 RPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSG-GLAV 402
S+ + S+ + R HS+V H + + ++ GSG G
Sbjct: 1726 -SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS------GHSSAYSQHGSGSGHFC 1778
Query: 403 SGGGFGETEPQGGAWTAEGSHAG 425
S G G T Q + EGS G
Sbjct: 1779 SQGQHGSTSGQSSTFDQEGSSTG 1801
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/253 (25%), Positives = 92/253 (36%), Gaps = 33/253 (13%)
Query: 180 HGEGSAWAPSGKYRQAHGEG-----GPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVR 234
HG GS+ + SG RQ G G G RG + + G R S+ +H G
Sbjct: 1105 HGSGSSQS-SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GSG 1160
Query: 235 VGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPR-GRRQGSADKH 293
+G G+ + + + + G + GS + RG R G GS+ +
Sbjct: 1161 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG-QHGSRSGQSSRGERHGSSSGSSSHY 1219
Query: 294 TERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLW 353
+ G G RQ S G HSP RH G GL H+ S+
Sbjct: 1220 GQHGS-GSRQSSGHGRQGSGSGHSPSRG------RH-------GSGLGHS-SSHGQHGSG 1264
Query: 354 TASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSG-GLAVSGGGFGETEP 412
+ S+ + R HS+V H + + ++ GSG G S G G T
Sbjct: 1265 SGRSSSRGPYESRSGHSSVFGQHESGS------GHSSAYSQHGSGSGHFCSQGQHGSTSG 1318
Query: 413 QGGAWTAEGSHAG 425
Q + EGS G
Sbjct: 1319 QSSTFDQEGSSTG 1331
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 33/253 (13%)
Query: 180 HGEGSAWAPSGKYRQAHGEG-----GPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVR 234
HG GS+ + SG RQ G G G RG + + G R S+ +H G
Sbjct: 2045 HGSGSSQS-SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GPG 2100
Query: 235 VGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPR-GRRQGSADKH 293
+G G+ + + + + G + GS + RG R G GS+ ++
Sbjct: 2101 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG-QHGSRSGQSSRGERHGSSSGSSSRY 2159
Query: 294 TERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLW 353
+ G G RQ S G HSP SR R G S+
Sbjct: 2160 GQHGS-GSRQSSGHGRQGSGSGHSP--------------SRGRHGSGSGHSSSHGQHGSG 2204
Query: 354 TASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSG-GLAVSGGGFGETEP 412
+ S+ + R HS+V H + + ++ GSG G S G G T
Sbjct: 2205 SGRSSSRGPYESRSGHSSVFGQHESGS------GHSSAYSQHGSGSGHFCSQGQHGSTSG 2258
Query: 413 QGGAWTAEGSHAG 425
Q + EGS G
Sbjct: 2259 QSSTFDQEGSSTG 2271
Score = 45.4 bits (106), Expect = 1e-04
Identities = 61/263 (23%), Positives = 99/263 (37%), Gaps = 25/263 (9%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG S A S G++ + + G H+ ++ + RG G + H +RG G
Sbjct: 377 HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSG-- 434
Query: 239 REVPTSTQRG---GRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTE 295
+ P+S Q G GR + + + G + S++ + G G + H +
Sbjct: 435 -QSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQ 493
Query: 296 RGPR------GRRQGSADGNHSEAPAHSPGGSDNQINCRH-----LELSRPRGGGLVHTR 344
G R G RQGS+ G+ S H G + + RH S RG +R
Sbjct: 494 HGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSR 553
Query: 345 PSNAAEPLWTASHHSQS--ALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAV 402
S++ P S S S + HS+ + H +S R + S G +
Sbjct: 554 QSSSYGPHGYGSGRSSSRGPYESGSGHSSGL-GHQES----RSGQSSGYGQHGSSSGHSS 608
Query: 403 SGGGFGETEPQGGAWTAEGSHAG 425
+ G G T Q + G+ +G
Sbjct: 609 THGQHGSTSGQSSSCGQHGATSG 631
Score = 43.1 bits (100), Expect = 7e-04
Identities = 59/259 (22%), Positives = 90/259 (34%), Gaps = 50/259 (19%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG GS W+ S G++ G+ G H+ S+ + + G G + + + G R G
Sbjct: 1848 HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG-- 1905
Query: 239 REVPTSTQRGGRVGAVREVRTSTLERGPRGPRQ-------GSTDKHTERGPRGRRQGSAD 291
+ RG + G+ +S + G G RQ GS + RGR +
Sbjct: 1906 -----QSSRGEQHGSSSGSSSSYGQHG-SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1959
Query: 292 KHTERGPRGRRQG--SADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAA 349
+ + GP G G S+ G + HS GL H R S +
Sbjct: 1960 QSSSYGPYGSGSGWSSSRGPYESGSGHS--------------------SGLGH-RESRSG 1998
Query: 350 EPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGE 409
+ H S S HS+ H ++ Q S G + S G G
Sbjct: 1999 QSSGYGQHGSSSG------HSSTHGQHGSASGQSSSCGQ-----HGASSGQSSSHGQHGS 2047
Query: 410 TEPQGGAWTAEGSHAGHIP 428
Q + +GS +G P
Sbjct: 2048 GSSQSSGYGRQGSGSGQSP 2066
Score = 41.2 bits (95), Expect = 0.003
Identities = 62/264 (23%), Positives = 91/264 (34%), Gaps = 34/264 (12%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG GS +PS G++ G G H + + G G G + G +
Sbjct: 1352 HGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF---GHHESSS 1408
Query: 239 REVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPR-GRRQGSADKHTERG 297
+ TQ G G +S+ E+ GS + RG R G GS+ + + G
Sbjct: 1409 WQSSGCTQHGSGSG-----HSSSYEQ------HGSRSGQSSRGERHGSSSGSSSSYGQHG 1457
Query: 298 PRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELS--RPRGGGLVHTRPSNAAEPLWTA 355
G RQ G H SP S + + S P G G + S++ P +
Sbjct: 1458 S-GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG---SGWSSSRGPYESG 1513
Query: 356 SHHSQSALQQRPDHSAVMCAH-VDSTPTPREQAQDTHPTREG----------SGGLAVSG 404
S HS S L R S + + + H + G S G + S
Sbjct: 1514 SSHS-SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1572
Query: 405 GGFGETEPQGGAWTAEGSHAGHIP 428
G G Q + +GS +G P
Sbjct: 1573 GQHGSGSSQSSGYGRQGSGSGQSP 1596
Score = 40.8 bits (94), Expect = 0.004
Identities = 60/278 (21%), Positives = 86/278 (30%), Gaps = 33/278 (11%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG GS W+ S G + G+ G H+ + + + G + + + G R G
Sbjct: 678 HGSGSGWSSSNGPHGSVSGQSSGFG-HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQS 736
Query: 239 REVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHT-ERGPRGRRQGSADKHTERG 297
G + + + + + G RQGS H+ R G G + H + G
Sbjct: 737 SRSEQHGSSSGLSSSYGQHGSGSHQSSGHG-RQGSGSGHSPSRVRHGSSSGHSSSHGQHG 795
Query: 298 P------------RGRRQGSADGNHSEAPA-----HSPGGSDNQINCRHLELSRPRGGGL 340
G Q S G H H RH S
Sbjct: 796 SGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSG 855
Query: 341 VHTRPSNAAEPLW---TASHHSQ------SALQQRPDHSAVMCAHVDSTPTPRE---QAQ 388
H S + +ASHH+ S Q P H S R +
Sbjct: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGR 915
Query: 389 DTHPTREGSGGLAVSGGGFGETEPQGGAWTAEGSHAGH 426
+ R GSG SG G + Q +T GS +GH
Sbjct: 916 SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGH 953
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/164 (23%), Positives = 65/164 (39%), Gaps = 22/164 (13%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG S + S G++ + G+ G H+ ++ + RG G G + H +RG G
Sbjct: 844 HGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG-- 901
Query: 239 REVPTSTQRGGRVGAVREVRTSTLERGPRGPRQ----------GSTDKHTERGPRGRRQG 288
+ P+ + G G R+S+ R G Q G + +T+ G
Sbjct: 902 -QSPSYGRHGSGSG-----RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSS 955
Query: 289 SADKHTER---GPRGRRQGSADGNHSEAPAHSPGGSDNQINCRH 329
S ++H R R + GS+ G+ S H G + + +H
Sbjct: 956 SYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQH 999
Score = 39.7 bits (91), Expect = 0.008
Identities = 57/263 (21%), Positives = 87/263 (33%), Gaps = 58/263 (22%)
Query: 180 HGEGSAWAPS-GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAV 238
HG GS W+ S G++ G+ G H+ S+ + + G G + + + G R G
Sbjct: 2318 HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG-- 2375
Query: 239 REVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGP 298
+ RG R GS+ GS+ + + G
Sbjct: 2376 -------------------------QSSRGERHGSSS------------GSSSSYGQHGS 2398
Query: 299 RGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELS--RPRGGGLVHTRPSNAAEPLWTAS 356
G RQ G H SP S + + S P G G + S++ P + S
Sbjct: 2399 -GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG---SGWSSSRGPYESGS 2454
Query: 357 HHSQSALQQRPDHSAVMCAH-VDSTPTPREQAQDTHPTREG----------SGGLAVSGG 405
HS S L R S + + + H + G S G + S G
Sbjct: 2455 GHS-SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
Query: 406 GFGETEPQGGAWTAEGSHAGHIP 428
G Q + +GS +G P
Sbjct: 2514 QHGSGSSQSSGYGRQGSGSGQSP 2536
Score = 33.5 bits (75), Expect = 0.56
Identities = 55/270 (20%), Positives = 91/270 (33%), Gaps = 29/270 (10%)
Query: 179 AHGEGSAWAPSGKYRQAHGEGGP-------RGPHQGSTDKHTERGPRGPRQGSTDKHTER 231
++G+ + + R HG G RG G + + G R S+ +H
Sbjct: 866 SYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSG 925
Query: 232 GVRVGAVREVPTSTQRGG--RVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGS 289
+ +S Q G + G+ +S + G R + +++H G GS
Sbjct: 926 SGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH------GSSSGS 979
Query: 290 ADKHTERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAA 349
+ + + G G RQ G H SP S + + S G + S++
Sbjct: 980 SSSYGQHG-SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ-SSSYGPYRSGSGWSSSR 1037
Query: 350 EPLWTASHHSQSALQQRPDHSAVMCAH-VDSTPTPREQAQDTHPTREG----------SG 398
P + S HS S L R S + + + H + G S
Sbjct: 1038 GPYESGSGHS-SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS 1096
Query: 399 GLAVSGGGFGETEPQGGAWTAEGSHAGHIP 428
G + S G G Q + +GS +G P
Sbjct: 1097 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126
Score = 29.6 bits (65), Expect = 8.1
Identities = 45/255 (17%), Positives = 83/255 (32%), Gaps = 28/255 (10%)
Query: 189 SGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRG 248
SG++ G+ G + + + RG G G + + + G G T
Sbjct: 166 SGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGS 225
Query: 249 GRVGAVREVRTSTLERGPRGP------------RQGSTDKHTERGPRGR-RQGSADKHTE 295
G+ + ++S+ + + GS + RG R R GS+ + +
Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
Query: 296 RGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTA 355
G G RQ G SP H+ G H + + + ++
Sbjct: 286 HG-SGSRQSLGHGRQGSGSRQSPS---------HVRHGSGSGHSSSHGQHGSGSSYSYSR 335
Query: 356 SHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREG----SGGLAVSGGGFGETE 411
H+ +S Q S+ + + H + +G + G A S G G +
Sbjct: 336 GHY-ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSS 394
Query: 412 PQGGAWTAEGSHAGH 426
Q ++ S + H
Sbjct: 395 RQSSSYGQHESASRH 409
>gi|239756601 PREDICTED: hypothetical protein [Homo sapiens]
Length = 82
Score = 52.4 bits (124), Expect = 1e-06
Identities = 26/40 (65%), Positives = 29/40 (72%)
Query: 106 VSTRPALPLPLPEGSKRSLWEPVNLVVSVSLDTVGDEMAF 145
+S RPA+PLPLP SKRSLWEPV L+VSVS T AF
Sbjct: 1 MSCRPAMPLPLPLSSKRSLWEPVYLLVSVSRSTAPPVFAF 40
>gi|239751093 PREDICTED: hypothetical protein [Homo sapiens]
Length = 82
Score = 52.4 bits (124), Expect = 1e-06
Identities = 26/40 (65%), Positives = 29/40 (72%)
Query: 106 VSTRPALPLPLPEGSKRSLWEPVNLVVSVSLDTVGDEMAF 145
+S RPA+PLPLP SKRSLWEPV L+VSVS T AF
Sbjct: 1 MSCRPAMPLPLPLSSKRSLWEPVYLLVSVSRSTAPPVFAF 40
>gi|239745582 PREDICTED: hypothetical protein XP_002344135 [Homo
sapiens]
Length = 82
Score = 52.4 bits (124), Expect = 1e-06
Identities = 26/40 (65%), Positives = 29/40 (72%)
Query: 106 VSTRPALPLPLPEGSKRSLWEPVNLVVSVSLDTVGDEMAF 145
+S RPA+PLPLP SKRSLWEPV L+VSVS T AF
Sbjct: 1 MSCRPAMPLPLPLSSKRSLWEPVYLLVSVSRSTAPPVFAF 40
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/307 (24%), Positives = 108/307 (35%), Gaps = 63/307 (20%)
Query: 142 EMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGP 201
E A K SRR+G+ + R +E H E S + E
Sbjct: 1580 ESAGSKTSRRQGSSVSQDRDSE---------------GHSEDS---------ERRSESAS 1615
Query: 202 RGPHQGSTDKHTERGPRGPRQGSTDK----HTERGVRVGAVREVPTSTQRGGRVGAVREV 257
R H GS + + G R PR D+ H+ R R TS+ GG+ + +E
Sbjct: 1616 RN-HYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSS--GGQAASSQEQ 1672
Query: 258 RTSTLERGPRGPRQGSTDKHTERGPRGRRQGSA--DKHTERGPRGRRQGSADGNHSEA-- 313
S+ Q S D T+ G GRRQ S+ RG G + ++G+ E+
Sbjct: 1673 ARSSPGERHGSRHQQSADSSTDSG-TGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731
Query: 314 ---PAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSAL------- 363
AH G Q H E +R + G R + L+ S H QS
Sbjct: 1732 QSVSAHGQAGPHQQ---SHQESTRGQSG----ERSGRSGSFLYQVSTHEQSESAHGRTGP 1784
Query: 364 ----QQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTA 419
+QR H A S + ++ QDT GS G + ++ G
Sbjct: 1785 STGGRQRSRHEQ---ARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSG---H 1838
Query: 420 EGSHAGH 426
GSH H
Sbjct: 1839 SGSHHSH 1845
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/235 (22%), Positives = 90/235 (38%), Gaps = 16/235 (6%)
Query: 137 DTVGDEMAFCKRSRR---KGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYR 193
D++ +E +RSR K + ++ R E Q P +++R ++ S S +
Sbjct: 248 DSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHS 307
Query: 194 Q--AHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDK----HTERGVRVGAVREVPTSTQR 247
+ G H GS + + G R PR D+ H+ R R TS+ R
Sbjct: 308 EDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSS-R 366
Query: 248 GGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSAD 307
G + + R+S ER G +Q + RG+ + RG G + ++
Sbjct: 367 GQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSE 426
Query: 308 GN--HSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQ 360
G+ +S+ + S G H E +R R G R + L+ S H Q
Sbjct: 427 GHSENSDTQSVSGHGKAGLRQQSHQESTRGRSG----ERSGRSGSSLYQVSTHEQ 477
Score = 47.8 bits (112), Expect = 3e-05
Identities = 76/332 (22%), Positives = 111/332 (33%), Gaps = 74/332 (22%)
Query: 151 RKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGP------ 204
R +G A R Y K+ + +R H E S+WA S ++ G+G GP
Sbjct: 2181 RGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLV-GQGQSSGPRTSRPR 2239
Query: 205 ---------------------------HQGSTDKHTERGPRGPRQGSTDK----HTERGV 233
H GS + + G R PR D+ H+
Sbjct: 2240 GSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESS 2299
Query: 234 RVGAVREVPTSTQRGGRVGAVRE-VRTSTLER-GPRGPRQGSTDKHTERGPRGRRQGSAD 291
R S+ GG+ + E R+S ER G + + +H+ G G+ +
Sbjct: 2300 RQSGTHHAENSS--GGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG-HGQASSAVR 2356
Query: 292 KHTERGPRGRRQGSADGNHSE------APAHSPGGSDNQINCRHLELSRPRGGGLVHTRP 345
RG G + ++G HSE AH G Q H E +R R G R
Sbjct: 2357 DSGHRGSSGSQASDSEG-HSEDSDTQSVSAHGQAGPHQQ---SHQESTRGRSAG----RS 2408
Query: 346 SNAAEPLWTASHHSQSAL-----------QQRPDHSAVMCAHVDSTPTPREQAQDTHPTR 394
+ L+ S H QS +Q H A S + ++ QDT
Sbjct: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQ---ARDSSRHSTSQEGQDTIHGH 2465
Query: 395 EGSGGLAVSGGGFGETEPQGGAWTAEGSHAGH 426
GS G + + + G GSH H
Sbjct: 2466 PGSSSGGRQGSHYEQLVDRSG---HSGSHHSH 2494
Score = 41.6 bits (96), Expect = 0.002
Identities = 68/312 (21%), Positives = 101/312 (32%), Gaps = 44/312 (14%)
Query: 148 RSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAH-----GEGGPR 202
R +G A E + +P E+ + Q + S + +G+ + + G G
Sbjct: 1656 RHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSS 1715
Query: 203 GPHQGSTDKHTER---------GPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGA 253
G ++ H+E G GP Q S + T RG S +R GR G+
Sbjct: 1716 GSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQEST-RG----------QSGERSGRSGS 1764
Query: 254 ----VREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKH---TERG----PRGRR 302
V S G GP G + R + SA + T RG RG R
Sbjct: 1765 FLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 1824
Query: 303 QGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTAS------ 356
QGS ++ HS + + ++SR + G +R + + S
Sbjct: 1825 QGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSR 1884
Query: 357 HHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVS--GGGFGETEPQG 414
HH S+ HS V T R Q + G S G G
Sbjct: 1885 HHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLG 1944
Query: 415 GAWTAEGSHAGH 426
AW + H
Sbjct: 1945 SAWEQSRDGSRH 1956
Score = 41.2 bits (95), Expect = 0.003
Identities = 71/272 (26%), Positives = 99/272 (36%), Gaps = 33/272 (12%)
Query: 147 KRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWA-PSGKYRQA--HGEGGPRG 203
+ S R +GE R +L Q K +HG W PS RQ H +
Sbjct: 776 QESARDRSGERSRRSGSFLYQVSTHKQS--ESSHG----WTGPSTGVRQGSHHEQARDNS 829
Query: 204 PHQGSTD-KHTERG-PRGPRQGSTDKHTERGV----RVGAVREVPTSTQRG----GRVGA 253
H S D + T RG P R+G H E+ V G+ TS R G+ G+
Sbjct: 830 RHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS 889
Query: 254 VREVRTSTLERGPRGPRQGSTDKHTERGPRG--RRQGSADKHTERGPR-GRRQGSADGNH 310
RT+ E R + S +H E R A + G R RRQGS+
Sbjct: 890 RSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQD 949
Query: 311 SEAPAHSP-----GGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQ 365
S++ HS GS ++ N R + R G P + E H + S+ Q
Sbjct: 950 SDSEGHSEDSERWSGSASR-NHRGSAQEQSRHGS---RHPRSHHEDRAGHGHSADSSRQS 1005
Query: 366 RPDHSAVMCAHVDSTPTPREQAQDTHPTREGS 397
H+ + EQA+ + R GS
Sbjct: 1006 GTPHAETSSG--GQAASSHEQARSSPGERHGS 1035
Score = 40.4 bits (93), Expect = 0.005
Identities = 68/324 (20%), Positives = 106/324 (32%), Gaps = 63/324 (19%)
Query: 154 AGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGP--------- 204
+G A R ++ + TR H E S+ A S ++ Q G+G GP
Sbjct: 562 SGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQV-GQGQSSGPRTSRNQGSS 620
Query: 205 ------------------------HQGSTDKHTERGPRGPRQGSTDK----HTERGVRVG 236
H GS + + G R PR D+ H+ R
Sbjct: 621 VSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKS 680
Query: 237 AVREVPTSTQRGGRVGAVREVRTSTLER-GPRGPRQGSTDKHTERGPRGRRQGSADKHTE 295
R S+ G + + R+S ER G R Q + G+ +
Sbjct: 681 GTRHTQNSSS-GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH 739
Query: 296 RGPRGRRQGSADGNHSEAPAHSPGGSDNQINCR--HLELSRPRGGGLVHTRPSNAAEPLW 353
RG G + ++G+ ++ S G + + H E +R R G R + L+
Sbjct: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG----ERSRRSGSFLY 795
Query: 354 TASHHSQS-----------ALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAV 402
S H QS ++Q H A +S + + QDT GS
Sbjct: 796 QVSTHKQSESSHGWTGPSTGVRQGSHHEQ---ARDNSRHSASQDGQDTIRGHPGSSRRGR 852
Query: 403 SGGGFGETEPQGGAWTAEGSHAGH 426
G ++ + G GSH H
Sbjct: 853 QGSHHEQSVDRSG---HSGSHHSH 873
Score = 40.4 bits (93), Expect = 0.005
Identities = 56/238 (23%), Positives = 86/238 (36%), Gaps = 26/238 (10%)
Query: 205 HQGSTDKHTERGPRGPRQGSTDK----HTERGVRVGAVREVPTSTQRGGRVGAVRE-VRT 259
H+GS + + G R PR D+ H+ R TS+ GG+ + E R+
Sbjct: 970 HRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSS--GGQAASSHEQARS 1027
Query: 260 STLER-GPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAHSP 318
S ER G R + + +H+ PR + + G G + ++G+ E+ S
Sbjct: 1028 SPGERHGSRHQQSADSSRHSGI-PRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSV 1086
Query: 319 G--GSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQ--------RPD 368
G D H E +R GG R + ++ S H QS R
Sbjct: 1087 SGHGQDGPHQQSHQESARDWSGG----RSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQ 1142
Query: 369 HSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAEGSHAGH 426
S A S + ++ QDT GS G ++ + G GSH H
Sbjct: 1143 GSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSG---HSGSHHSH 1197
Score = 38.5 bits (88), Expect = 0.017
Identities = 72/303 (23%), Positives = 103/303 (33%), Gaps = 39/303 (12%)
Query: 140 GDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGE- 198
G + A R AGE R + +Q+ + +R HG+ S+ +R + G
Sbjct: 3608 GGQAASSHEQARSSAGE---RHGSHHQQSA-DSSRHSGIGHGQASSAVRDSGHRGSSGSQ 3663
Query: 199 -GGPRGPHQGS-TDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGA--- 253
G + S T + G GP Q S + T RG G R GR G+
Sbjct: 3664 ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST-RGRSAG----------RSGRSGSFLY 3712
Query: 254 -VREVRTSTLERGPRGP----RQGSTDKHTERGPRGRRQGSAD-KHTERGP----RGRRQ 303
V S G GP RQGS +H + R S + + T RG RG RQ
Sbjct: 3713 QVSTHEQSESAHGRAGPSTGGRQGS--RHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770
Query: 304 GSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSAL 363
GS + HS + + + S + G +R + E S HS S
Sbjct: 3771 GSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR- 3829
Query: 364 QQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAEGSH 423
H S + Q + R G +VS E P+ +E +
Sbjct: 3830 -----HHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESAS 3884
Query: 424 AGH 426
H
Sbjct: 3885 RNH 3887
Score = 38.1 bits (87), Expect = 0.023
Identities = 67/299 (22%), Positives = 99/299 (33%), Gaps = 30/299 (10%)
Query: 140 GDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEG 199
G + A R AGE R + +Q+ + +R HG+ S+ +R
Sbjct: 2636 GGQAASSHEQARSSAGE---RHGSHHQQSA-DSSRHSGIGHGQASSAVRDSGHR------ 2685
Query: 200 GPRGPHQGSTDKHTERGPRGP--RQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREV 257
G G + H+E G H + R TS G + V
Sbjct: 2686 GYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTH 2745
Query: 258 RTSTLERGPRGP----RQGSTDKHTERGPRGRRQGSAD-KHTERG----PRGRRQGSADG 308
S G GP RQGS +H + R S D + T RG RG RQG
Sbjct: 2746 EQSESSHGWTGPSTRGRQGS--RHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHE 2803
Query: 309 NHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPD 368
+ ++ HS + + + SR + G +R + E S HS S +
Sbjct: 2804 HSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEAST 2863
Query: 369 HSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGG-AWTAEGSHAGH 426
H+ + S + Q Q R G +VS E + W+ S H
Sbjct: 2864 HADI------SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHH 2916
Score = 37.7 bits (86), Expect = 0.030
Identities = 48/217 (22%), Positives = 70/217 (32%), Gaps = 16/217 (7%)
Query: 178 QAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGA 237
+ HG G + A G RG + RG G + ++ H+E
Sbjct: 382 ERHGSGHQQSADSSRHSATG----RGQASSAVSDRGHRGSSGSQASDSEGHSENS----- 432
Query: 238 VREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERG 297
T + G +R+ RG G R G + + + SA T
Sbjct: 433 ----DTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTS 488
Query: 298 PRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASH 357
GR QGS ++ HS H SR G H + N + + SH
Sbjct: 489 TGGR-QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGH--SGSH 545
Query: 358 HSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTR 394
HS + Q R D S ++ R + Q TR
Sbjct: 546 HSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTR 582
Score = 37.4 bits (85), Expect = 0.039
Identities = 52/207 (25%), Positives = 72/207 (34%), Gaps = 39/207 (18%)
Query: 190 GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTD-KHTERGVRVGAVREVPTSTQRG 248
G+ H + R H GS HT QG +D H + G R A RE Q G
Sbjct: 3768 GRQGSYHEQSVDRSGHSGSHHSHTTS------QGRSDASHGQSGSR-SASRETRNEEQSG 3820
Query: 249 --GRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSA--------------DK 292
R R ST R + G + R R RRQGS+ ++
Sbjct: 3821 DGSRHSGSRHHEASTQADSSRHSQSGQGESAGSR--RSRRQGSSVSQDSDSEAYPEDSER 3878
Query: 293 HTERGPRGR----RQGSADGNHSEAPAH---------SPGGSDNQINCRHLELSRPRGGG 339
+E R R+ S DG+ +H SP SD+ H S
Sbjct: 3879 RSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDS 3938
Query: 340 LVHTRPSNAAEPLWTASHHSQSALQQR 366
H+ + P ++S+H QS +R
Sbjct: 3939 AYHSGIQSRGSPHSSSSYHYQSEGTER 3965
Score = 35.8 bits (81), Expect = 0.11
Identities = 57/267 (21%), Positives = 96/267 (35%), Gaps = 34/267 (12%)
Query: 154 AGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGE---GGPRGPHQGS-- 208
+G A R + + +R H E ++WA S ++ Q E G HQGS
Sbjct: 1211 SGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSV 1270
Query: 209 -----TDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLE 263
+++H++ R S + H G+ RE ++ G R + ++
Sbjct: 1271 SQDSDSERHSDDSERLSGSASRNHH-------GSSRE---QSRDGSRHPGFHQEDRASHG 1320
Query: 264 RGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAHSPGGSDN 323
RQ T HTE G+ S ++ R G R GS +++ HS G
Sbjct: 1321 HSADSSRQSGT-HHTESSSHGQAVSSHEQ--ARSSPGERHGSRHQQSADSSRHSGIGHRQ 1377
Query: 324 QINCRHLELSRPRGGGLVHTRPSNAAE-PLWTASHHSQSALQQRPDHSAVMCAHVDSTPT 382
+ R G V ++ + + S H Q+ Q+ + +S+
Sbjct: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437
Query: 383 PR---------EQAQDTH-PTREGSGG 399
R EQ++ TH T +GG
Sbjct: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGG 1464
Score = 35.8 bits (81), Expect = 0.11
Identities = 70/320 (21%), Positives = 106/320 (33%), Gaps = 32/320 (10%)
Query: 140 GDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEG 199
G + A R AGE R + +Q+ + +R HG+ S+ +R
Sbjct: 2960 GGQAASSHEQARSSAGE---RHGSHHQQSA-DSSRHSGIGHGQASSAVRDSGHR------ 3009
Query: 200 GPRGPHQGSTDKHTERGPRGP--RQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREV 257
G G + H+E G H + R TS G + V
Sbjct: 3010 GYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTH 3069
Query: 258 RTSTLERGPRGP----RQGSTDKHTERGPRGRRQGSA-DKHTERG----PRGRRQGSADG 308
S G GP RQGS +H + R S + T RG RG RQG
Sbjct: 3070 EQSESSHGWTGPSTRGRQGS--RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHE 3127
Query: 309 NHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPD 368
+ ++ HS + + + SR + G +R + E +S HS S +
Sbjct: 3128 HSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEAST 3187
Query: 369 HSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGG-AWTAEGS--HAG 425
H+ + S + Q Q R G +VS E + W+ S H G
Sbjct: 3188 HADI------SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG 3241
Query: 426 HIPDPPAIGRCCPAASPRGR 445
+ + G P + R
Sbjct: 3242 SVQEQSRHGSRHPRSHHEDR 3261
Score = 34.7 bits (78), Expect = 0.25
Identities = 56/237 (23%), Positives = 84/237 (35%), Gaps = 30/237 (12%)
Query: 151 RKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHG------EGGPRGP 204
R AGE R + + +R HG+ S+ +R + G EG
Sbjct: 701 RSSAGERHGSRHQLQSA---DSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDS 757
Query: 205 HQGSTDKHTERG--PRGPRQGSTDKHTERGVRVGA-VREVPTSTQRGGRVGAVREVRTST 261
S H + G + ++ + D+ ER R G+ + +V T Q G
Sbjct: 758 DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWT------- 810
Query: 262 LERGPR-GPRQGSTDKHTERGPRGRRQGSAD-KHTERGPRGR----RQGSADGNHSEAPA 315
GP G RQGS H + R S D + T RG G RQGS +
Sbjct: 811 ---GPSTGVRQGS--HHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSG 865
Query: 316 HSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAV 372
HS + + + SR + G +R + E S HS S + H+ +
Sbjct: 866 HSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADI 922
Score = 33.1 bits (74), Expect = 0.73
Identities = 69/288 (23%), Positives = 94/288 (32%), Gaps = 55/288 (19%)
Query: 140 GDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEG 199
G + A R GE R + + RQA SA SG + + +
Sbjct: 1015 GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQA---SSAVRDSGHWGSSGSQA 1071
Query: 200 GPRGPHQGSTDKHTE--RGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGA-VRE 256
H +D + G GP Q S H E + R+ S R GR G+ + +
Sbjct: 1072 SDSEGHSEESDTQSVSGHGQDGPHQQS---HQE------SARD--WSGGRSGRSGSFIYQ 1120
Query: 257 VRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAH 316
V T G + ST GRRQGS H E+ R ++ AH
Sbjct: 1121 VSTHEQSESAHGRTRTST---------GRRQGS---HHEQARDSSRHSASQEGQDTIRAH 1168
Query: 317 SPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAVMCAH 376
PG H E S R G + SHHS + Q R D S H
Sbjct: 1169 -PGSRRGGRQGSHHEQSVDRSG--------------HSGSHHSHTTSQGRSDAS-----H 1208
Query: 377 VDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAEGSHA 424
S R ++ T ++ G SG E +W H+
Sbjct: 1209 GQS--GSRSASRQTRKDKQSGDGSRHSGSRHHE----AASWADSSRHS 1250
Score = 31.2 bits (69), Expect = 2.8
Identities = 53/221 (23%), Positives = 78/221 (35%), Gaps = 20/221 (9%)
Query: 151 RKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGE--GGPRGPHQGS 208
R AGE R + + + +R HG+ S+ +R G G + S
Sbjct: 1998 RSSAGE---RHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDS 2054
Query: 209 -TDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPR 267
T + +G GP Q S K + RG + +S + G + V S G
Sbjct: 2055 DTQSVSAQGKAGPHQQS-HKESARG------QSGESSGRSGSFLYQVSTHEQSESTHGQS 2107
Query: 268 GP----RQGSTDKHTERGPR--GRRQGSADKHTERGP-RGRRQGSADGNHSEAPAHSPGG 320
P RQGS + R ++G GP RG RQGS + HS
Sbjct: 2108 APSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSH 2167
Query: 321 SDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQS 361
+ + + SR + G +R + E S HS S
Sbjct: 2168 HSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGS 2208
Score = 30.4 bits (67), Expect = 4.8
Identities = 66/290 (22%), Positives = 97/290 (33%), Gaps = 53/290 (18%)
Query: 163 EYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAH------GEGGPRGPHQGSTDKHTE-- 214
E + +P E+ + Q + S + G +RQA G G G +++ H+E
Sbjct: 1347 EQARSSPGERHGSRHQQSADSSRHSGIG-HRQASSAVRDSGHRGSSGSQVTNSEGHSEDS 1405
Query: 215 -------RGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPR 267
G GP Q S K + RG Q G G R
Sbjct: 1406 DTQSVSAHGQAGPHQQS-HKESARG-------------QSGESSGRSRSFLYQVSSHEQS 1451
Query: 268 GPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHS--EAPAHSPGGSDNQI 325
G T T G RQGS +H + R S DG + P S GG
Sbjct: 1452 ESTHGQTAPST-----GGRQGS--RHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSY 1504
Query: 326 NCRHLELSRPRGGGLVHTRPSNAAEPLWTASH-----HSQSALQQRPDHSAVMCAHVDST 380
+ + ++ S G HT P ++ ASH S S + + S H S
Sbjct: 1505 HEQSVDRSGHSGYHHSHTTPQGRSD----ASHGQSGPRSASRQTRNEEQSGDGSRHSGSR 1560
Query: 381 -PTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWTAEGSHAGHIPD 429
P +A + ++ G G G + QG + + + GH D
Sbjct: 1561 HHEPSTRAGSSRHSQVGQG----ESAGSKTSRRQGSSVSQDRDSEGHSED 1606
Score = 30.4 bits (67), Expect = 4.8
Identities = 63/281 (22%), Positives = 98/281 (34%), Gaps = 46/281 (16%)
Query: 166 KQTPPEK-----TRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGP 220
+QT EK +R H E S+ A S ++ Q G+G GP +G
Sbjct: 1866 RQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQV-GQGQSSGPRTSRN-----QGSSVS 1919
Query: 221 RQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDK--HT 278
+ + H+E R S R A + R G R P D+ H
Sbjct: 1920 QDSDSQGHSEDSERWSG------SASRNHLGSAWEQSRD-----GSRHPGSHHEDRAGHG 1968
Query: 279 ERGPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGG 338
R+ G+ +HTE RG Q ++ + + A GS +Q+ R
Sbjct: 1969 HSADSSRQSGT--RHTESSSRG--QAASSHEQARSSAGERHGSHHQLQ----SADSSRHS 2020
Query: 339 GLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSG 398
G+ H + S+A + H S Q H + + T AQ + S
Sbjct: 2021 GIGHGQASSAVR---DSGHRGYSGSQASDSE-----GHSEDSDTQSVSAQGKAGPHQQSH 2072
Query: 399 GLAVSGGGFGETEPQGGAW-----TAEGSHAGHIPDPPAIG 434
+ G GE+ + G++ T E S + H P+ G
Sbjct: 2073 KESARGQS-GESSGRSGSFLYQVSTHEQSESTHGQSAPSTG 2112
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 46.2 bits (108), Expect = 8e-05
Identities = 76/327 (23%), Positives = 110/327 (33%), Gaps = 57/327 (17%)
Query: 147 KRSRRKGAGELRA----RRAEYLKQTPPEKTRACR---QAHGEGSAWAPSGKYRQAHGEG 199
K+ RR+G A R A + P K R R G+ W GK + G+
Sbjct: 272 KKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQK 331
Query: 200 GPRGPHQGSTDKHTERGPRGPRQG------STDKHTERGV--RVGAVREVPTSTQRGGRV 251
+ G T+RG G ++ S K RG R ++ GG
Sbjct: 332 ATKAAAAG-----TKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDK 386
Query: 252 GAVREV------RTSTLERGPRG---------PRQGSTDKHTERGPRGRRQGSADKHTER 296
+RE R + PR PR G + K RGP+ + +
Sbjct: 387 KGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGG 446
Query: 297 GPRGRRQG-SADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTA 355
G + RR+G A +EA A S G ++ RGGGL S++ + LW
Sbjct: 447 GKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGL----KSHSGKNLWRR 502
Query: 356 SHHSQSA-----------------LQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSG 398
+++A +Q+P + S R++A T G G
Sbjct: 503 GQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGG 562
Query: 399 GLAVSGGGFGETEPQGGAWTAEGSHAG 425
G S GG G Q G A G
Sbjct: 563 GNKQSRGGGGNKPRQWGQTAAAAKTRG 589
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 45.4 bits (106), Expect = 1e-04
Identities = 55/183 (30%), Positives = 68/183 (37%), Gaps = 19/183 (10%)
Query: 198 EGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREV 257
E G P Q S ++R P + S +ER R + R + +QR R G
Sbjct: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHR-GPSERS 1685
Query: 258 RTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGP--RGRRQGSADGNH--SEA 313
S ER R P Q S RGP RR S K + R P R R S +H SE
Sbjct: 1686 HCSPSERRHRSPSQRS-----HRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER 1740
Query: 314 PAHSPG-----GSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWT-ASHHSQSALQQRP 367
HSP + +C E S H PS + SHHS S +R
Sbjct: 1741 SHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPS---ERS 1797
Query: 368 DHS 370
HS
Sbjct: 1798 HHS 1800
Score = 36.2 bits (82), Expect = 0.087
Identities = 44/185 (23%), Positives = 62/185 (33%), Gaps = 28/185 (15%)
Query: 198 EGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREV 257
E PRGP + + + R R P + S ER + R + +++ + R
Sbjct: 1547 ERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSW 1606
Query: 258 RT---------------STLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGR- 301
R+ S ERG P Q S RGP RR S + + R P R
Sbjct: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRS-----HRGPSQRRHHSPSERSHRSPSERS 1661
Query: 302 RQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQS 361
+ S++ H S G + +C E H PS HHS S
Sbjct: 1662 HRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSE-------RRHHSPS 1714
Query: 362 ALQQR 366
R
Sbjct: 1715 KRSHR 1719
Score = 30.4 bits (67), Expect = 4.8
Identities = 41/192 (21%), Positives = 61/192 (31%), Gaps = 29/192 (15%)
Query: 142 EMAFCKRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGP 201
E + C S R R ++P E+ + E S +PS + + E
Sbjct: 1755 ERSHCSPSERSHCSPSERRH-----RSPSERRH---HSPSEKSHHSPSERSHHSPSERRR 1806
Query: 202 RGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTST 261
P + S ER R P + + + ER R + E S + + R S
Sbjct: 1807 HSPLERSRHSLLERSHRSPSERRSHRSFERSHR--RISERSHSPSEKSHLSPLERSRCSP 1864
Query: 262 LER-------------------GPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRR 302
ER P G RQG T + + R R + S + P GR
Sbjct: 1865 SERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRN 1924
Query: 303 QGSADGNHSEAP 314
S +P
Sbjct: 1925 HCSPSERSRRSP 1936
Score = 30.0 bits (66), Expect = 6.2
Identities = 44/187 (23%), Positives = 67/187 (35%), Gaps = 21/187 (11%)
Query: 149 SRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGS 208
S+R G R K++ R ++ E S +PS ++H R H S
Sbjct: 1698 SQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS---ERSHHSPSERRHHSPS 1754
Query: 209 TDKH-----------TERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREV 257
H +ER R P + +E+ + R + ++R R +
Sbjct: 1755 ERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSER-RRHSPLERS 1813
Query: 258 RTSTLERGPRGPRQGSTDKHTERGPR--GRRQGSADKHTERGP--RGRRQGSADGNHSEA 313
R S LER R P + + + ER R R S + + P R R S HS +
Sbjct: 1814 RHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSS 1873
Query: 314 --PAHSP 318
HSP
Sbjct: 1874 GKTCHSP 1880
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 44.3 bits (103), Expect = 3e-04
Identities = 65/248 (26%), Positives = 71/248 (28%), Gaps = 35/248 (14%)
Query: 183 GSAWAPSGKYRQAHGEGGPR-GPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREV 241
G P G G GGP GPH G GP GPR G +
Sbjct: 632 GGPGGPKGMQHFPPGPGGPMPGPHGGPG------GPVGPRLLGPPPPPRGG---DPFWDG 682
Query: 242 PTSTQRGG--RVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPR 299
P RGG R G RG RG + RG RG R G + GP
Sbjct: 683 PGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742
Query: 300 GRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGG-GLVHTRPSNAAEPLWTASHH 358
G G E P G S H P GG G H + H
Sbjct: 743 GGMVGGGGHRPHEGPGGGMGNSSG-----HRPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797
Query: 359 SQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGAWT 418
RP P H EG GG +GGG E GG+
Sbjct: 798 -------RPHEG----------PGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMG 840
Query: 419 AEGSHAGH 426
G H H
Sbjct: 841 GSGGHRPH 848
Score = 37.7 bits (86), Expect = 0.030
Identities = 55/237 (23%), Positives = 61/237 (25%), Gaps = 52/237 (21%)
Query: 169 PPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKH 228
PP R A G S P +G GGP G G GP G S+
Sbjct: 715 PPPPPPPFRGARGGRSGGGPP------NGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHR 768
Query: 229 TERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQG 288
G GG +G+ GP G G GP G G
Sbjct: 769 PHEGP--------------GGGMGSGHRPH-----EGPGGSMGGGGGHRPHEGPGGGISG 809
Query: 289 SADKHTERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNA 348
+ GP G E P S GGS H P GG RP +
Sbjct: 810 GSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGG-----HRPHEGPGHGGPHGHRPHDV 864
Query: 349 AEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGG 405
P H H P P E P G G GG
Sbjct: 865 ------------------PGHR----GHDHRGPPPHEHRGHDGPGHGGGGHRGHDGG 899
Score = 35.4 bits (80), Expect = 0.15
Identities = 46/170 (27%), Positives = 53/170 (31%), Gaps = 24/170 (14%)
Query: 177 RQAHGEGSAWAPSGKYRQAHGEGGPRG----PHQGSTDK-------HTERGPRGPRQGST 225
R G G S +R G GG G PH+G GP G G +
Sbjct: 752 RPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGS 811
Query: 226 DK--HTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTER--- 280
H G +GA GG +G S R GP G H
Sbjct: 812 GHRPHEGPGGGMGAGGGHRPHEGPGGSMGG------SGGHRPHEGPGHGGPHGHRPHDVP 865
Query: 281 GPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAHSPGGS-DNQINCRH 329
G RG H RG G G G+ HS GG N+ CRH
Sbjct: 866 GHRGHDHRGPPPHEHRGHDGPGHGGG-GHRGHDGGHSHGGDMSNRPVCRH 914
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 43.9 bits (102), Expect = 4e-04
Identities = 72/274 (26%), Positives = 109/274 (39%), Gaps = 41/274 (14%)
Query: 178 QAHGEGSAWAPSGKYRQAHGEGGPRGPHQ----GSTDKHTERGPRGPRQGSTDKHTERGV 233
Q GSAW S RQA + R Q G T++ T++ G R +T+ ER
Sbjct: 155 QGQATGSAWVSSYD-RQAESQSQERISPQIQLSGQTEQ-TQKAGEGKRNQTTEMRPERQP 212
Query: 234 RVGAVREVPTSTQRGGRV-GAVREVR---TSTLERGPRGPRQGSTDKHTERGPRGRRQGS 289
+ RE + Q G V G+ + + T T+E+ + G T K T+ + +G
Sbjct: 213 QT---REQDRAHQTGETVTGSGTQTQAGATQTVEQDS-SHQTGRTSKQTQEATNDQNRG- 267
Query: 290 ADKHTERGPRGRRQGS--ADGNHSEAPAHSPGGSDNQINCRHLEL--SRPRGGGLVHTRP 345
TE +GR Q S G H++ A G+ Q + +E S G T+
Sbjct: 268 ----TETHGQGRSQTSQAVTGGHAQIQA----GTHTQTPTQTVEQDSSHQTGSTSTQTQE 319
Query: 346 SNAAEPLWTASH---HSQSALQQRPDHSAVMC-AHVDSTPTPREQA--------QDTHPT 393
S + T H SQ++ H+ + +H ++ R Q Q T
Sbjct: 320 STNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQT 379
Query: 394 REGSGG--LAVSGGGFGETEPQGGAWTAEGSHAG 425
+ GSG + VS GET P G A T + +G
Sbjct: 380 QPGSGQRWMQVSNPEAGETVPGGQAQTGASTESG 413
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 41.6 bits (96), Expect = 0.002
Identities = 65/270 (24%), Positives = 91/270 (33%), Gaps = 45/270 (16%)
Query: 195 AHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAV 254
AHG+ G + GS+ H G + G T +H G STQRG R
Sbjct: 2050 AHGQAGSQHGESGSS-VHERHGTTHGQTGDTTRHAHSGHG--------QSTQRGSRTAGR 2100
Query: 255 R-----EVRTSTLERGPRGPRQGST-----DKHTERGP-----RGRRQGSADKHTERGPR 299
R E S + G G T +H E G +G G T G
Sbjct: 2101 RGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQS 2160
Query: 300 GRRQGSADGNHS---EAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTAS 356
G Q + G+ + + +HS SD+++ H E S P G H++ S
Sbjct: 2161 GHGQSTQTGSRTTGRQRSSHSES-SDSEV---HSEAS-PTHSGHTHSQ---------AGS 2206
Query: 357 HHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDT-HPTREGSGGLAVSGGGFGETEPQGG 415
H QS H H + T R T+ GS G G E+
Sbjct: 2207 RHGQSGSS---GHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEV 2263
Query: 416 AWTAEGSHAGHIPDPPAIGRCCPAASPRGR 445
+H+GHI + P ++ GR
Sbjct: 2264 HSWGSHTHSGHIQGQAGSQQRQPGSTVHGR 2293
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 22/250 (8%)
Query: 177 RQAHGEGSAWAPSGKYRQAHGEGGPRGPH-QGSTDKHTERGPR--GPRQGSTDKHTERGV 233
R HGE + A G+ HG+ G H Q + T+ G R G ++ S + ++ V
Sbjct: 2130 RSQHGESGS-AIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEV 2188
Query: 234 RVGA--VREVPTSTQRGGRVGAVREVRTSTLERGPRGP-RQGSTDKHTERGPRGRRQGSA 290
A T +Q G R G + G G RQG+T T R G
Sbjct: 2189 HSEASPTHSGHTHSQAGSRHG----------QSGSSGHGRQGTTHGQTGDTTRHAHYGYG 2238
Query: 291 DKHTERGPRGR-RQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPR-GGGLVHTRPSNA 348
+ T+RG R R+GS S++ HS G + + + S+ R G VH R
Sbjct: 2239 -QSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETT 2297
Query: 349 AEPLWTASHHSQSALQQ--RPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGG 406
+ H S Q + + +H S + R++ + + GS G A G
Sbjct: 2298 HGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYG 2357
Query: 407 FGETEPQGGA 416
P GG+
Sbjct: 2358 HTGYGPSGGS 2367
Score = 40.4 bits (93), Expect = 0.005
Identities = 58/247 (23%), Positives = 80/247 (32%), Gaps = 37/247 (14%)
Query: 205 HQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLER 264
H+ S HT+ G P+ GST + R G T R G G + +T +
Sbjct: 1286 HRHSEHIHTQAGSHYPKSGSTVRR-----RQGTTHGQRGDTTRHGHSGHGQSTQTGSRTS 1340
Query: 265 G-PRGPRQGSTDKHTERGPRGRRQGSADKHTERGPR--------GRRQGSADGNHSEAPA 315
G R +TD G R H++ G + R + G EA
Sbjct: 1341 GRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATG 1400
Query: 316 HSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAVMCA 375
H G Q R + RG G H+ S+ +E SH QS Q H
Sbjct: 1401 HGHSG-HGQSTQRGSRTTGRRGSG--HSESSD-SEVHSGGSHRPQS---QEQTHGQAGSQ 1453
Query: 376 HVDSTPTPREQAQDTH----------------PTREGSGGLAVSGGGFGETEPQGGAWTA 419
H +S T + TH T+ GS G G E+
Sbjct: 1454 HGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGG 1513
Query: 420 EGSHAGH 426
+H+GH
Sbjct: 1514 SHTHSGH 1520
Score = 36.2 bits (82), Expect = 0.087
Identities = 62/269 (23%), Positives = 87/269 (32%), Gaps = 41/269 (15%)
Query: 177 RQAHGEG--SAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVR 234
+ HG+ S + +G+ R H E H G + HT G + S +E V
Sbjct: 1859 QSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGS--HTHSGHTHSQARSQHGESESTVH 1916
Query: 235 VGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHT 294
R T Q G T E G P G T + R R G ++
Sbjct: 1917 K---RHQTTHGQTG-----------DTTEHGH--PSHGQTIQTGSRTTGRRGSGHSEYSD 1960
Query: 295 ERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLEL-----------------SRPRG 337
GP G + H +A +H P S + ++ RH S RG
Sbjct: 1961 SEGPSGVSHTHSGHTHGQAGSHYP-ESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRG 2019
Query: 338 GGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGS 397
R S +E + H S H H +S + E+ TH +
Sbjct: 2020 SRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDT 2079
Query: 398 GGLAVSGGGFGETEPQGGAWTAEGSHAGH 426
A SG G Q G+ TA +GH
Sbjct: 2080 TRHAHSGHG---QSTQRGSRTAGRRGSGH 2105
Score = 32.0 bits (71), Expect = 1.6
Identities = 56/254 (22%), Positives = 85/254 (33%), Gaps = 35/254 (13%)
Query: 189 SGKYRQAHGEGGPRGPHQGSTDKHT--ERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQ 246
+G+ R +H E H G + HT G G + G ++ R G T
Sbjct: 1646 TGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPE--RHGTTHGQTGDTT 1703
Query: 247 RGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSA 306
R +T + G RG H+E G + H+ G G A
Sbjct: 1704 RHAHYHHGLTTQTGSRTTGRRG------SGHSEYSDSEGYSGVSHTHS-----GHTHGQA 1752
Query: 307 DGNH--SEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQ---- 360
H SE+ H G+ I+ + + +R G + + + +S HS+
Sbjct: 1753 RSQHGESESIVHERHGT---IHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDS 1809
Query: 361 ---SALQQRP-----DHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEP 412
S QRP H H +S E+ TH + G + SG G
Sbjct: 1810 EGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHG---QST 1866
Query: 413 QGGAWTAEGSHAGH 426
Q G+ T +GH
Sbjct: 1867 QSGSSTTGRRRSGH 1880
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 14/158 (8%)
Query: 147 KRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQ 206
+R R++ A + R R+ + +Q E+ R + K RQ E + +
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKERERE---------KNRQERRERERQREKE 198
Query: 207 GST-DKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERG 265
T D+H+ERG R+ T+ TER + R+ T+R A RE R S E
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE-RASERETE 257
Query: 266 PRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQ 303
R+ D+ + R RRQ ++ T+R + R +
Sbjct: 258 RDKERERERDRDRD---RDRRQKERERQTDRKRQRRTE 292
Score = 36.6 bits (83), Expect = 0.066
Identities = 37/151 (24%), Positives = 58/151 (38%), Gaps = 17/151 (11%)
Query: 148 RSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQG 207
R R + R R E +QT E+ R Q E + + + GE G G
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDR---QREKERNRQKERERETEREGERGRDRQTDG 145
Query: 208 STDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREV-RTSTLERGP 266
++ +R R+ TD+ +R T+R + RE R ER
Sbjct: 146 QRERERQRDAEKERERQTDRERQR------------QTERNRQKEREREKNRQERRERER 193
Query: 267 RGPRQGST-DKHTERGPRGRRQGSADKHTER 296
+ ++ T D+H+ERG R+ + TER
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETER 224
Score = 34.3 bits (77), Expect = 0.33
Identities = 39/157 (24%), Positives = 59/157 (37%), Gaps = 19/157 (12%)
Query: 147 KRSRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQ 206
KR RR+ R R +Q EK R RQ E + RQ E + +
Sbjct: 78 KRERRREKDRHRKRDRHRERQRDREKERE-RQTDRE--------RDRQREKERNRQKERE 128
Query: 207 GSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGP 266
T++ ERG R TD ER + A +E T R R+ +T +
Sbjct: 129 RETEREGERG----RDRQTDGQRERERQRDAEKERERQTDRE------RQRQTERNRQKE 178
Query: 267 RGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQ 303
R + ++ R + + D+H+ERG R+
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERE 215
Score = 32.7 bits (73), Expect = 0.96
Identities = 32/149 (21%), Positives = 54/149 (36%), Gaps = 11/149 (7%)
Query: 159 ARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPR 218
+RR +++P + R QAH + ++ + + TD+ ER
Sbjct: 27 SRRRPGSQESP--RRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 219 GPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHT 278
R D+H ER RE T +R R ER + R+ T++
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERD---------RQREKERNRQKERERETEREG 135
Query: 279 ERGPRGRRQGSADKHTERGPRGRRQGSAD 307
ERG + G ++ +R R+ D
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTD 164
>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
sapiens]
Length = 547
Score = 40.8 bits (94), Expect = 0.004
Identities = 71/281 (25%), Positives = 95/281 (33%), Gaps = 32/281 (11%)
Query: 82 GLPQAHPQVDSRTTAQQVTRVAVAVSTRPALPLPLPEGSKRSLWEPVNLVVSVSLDTVGD 141
GL +AH RT VTR + +P PLP +L P+ V V + GD
Sbjct: 162 GLERAHSPRARRT----VTRALTELLKQPGPQEPLPP----TLGPPLGGCVQVQM---GD 210
Query: 142 EMAFCKRSRRKGAGELRARRAE-----YLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAH 196
+ G R RA +++ PP A E +G +
Sbjct: 211 GLPRGSPHNSAGPRTPRLARASPPGEPFMRVAPPGLAAAAAARDSEPGPVPGAGGCGEDR 270
Query: 197 GEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVRE 256
PR P G H RG R+G ++ RG+ V + +R
Sbjct: 271 LGSQPR-PENGPPGSHRTASGRGLRRGDSEGGVNRGIGPSRVSLLAPDKKRLNNA----- 324
Query: 257 VRTSTLERGPRGPR---QGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGS-----ADG 308
R S PRGPR GS + + +A K PR RR + +
Sbjct: 325 PRGSAAPGPPRGPRLQGGGSLTLQPDYAKYATFKAAALKAAV--PRARRSANRLPRPSGP 382
Query: 309 NHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAA 349
APA SP S C L L RG L P+ AA
Sbjct: 383 RPRPAPARSPSQSPAGTPCPVLSLGARRGVTLPCPVPAEAA 423
>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 753
Score = 40.8 bits (94), Expect = 0.004
Identities = 79/315 (25%), Positives = 107/315 (33%), Gaps = 55/315 (17%)
Query: 204 PHQGSTDKHTERG--PRGPRQGSTDKHTE-RGVRVGAVR---------EVPTSTQRGGRV 251
P Q S D+ + G P G + T RG RV +VR ++ + Q G +
Sbjct: 17 PSQDSGDRVVKSGCGPSGATRPKTGAQPHPRGCRVPSVRSCALGAGQEQLARAAQPVGPL 76
Query: 252 GAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHS 311
GA R+S R P G + RGPRG + R G +A S
Sbjct: 77 GAAG--RSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRADPGASLAAA----S 130
Query: 312 EAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSA 371
+A G + RP GG L + + EP +Q P
Sbjct: 131 QAVCGRSAGHGLPPGVQEARTLRPDGGAL-RAQEAIPREP------------RQPPPEPE 177
Query: 372 VMC----AHVDSTPTPREQAQDTHPTREGSGGLAVSGGGFGETEPQGGA----------W 417
+ C PR + P GG AV+ G G P GG W
Sbjct: 178 LQCRLQVVRWLQLWQPRIPSSRLAPISADPGGDAVAKWGCG---PSGGTRRRSTTQPHPW 234
Query: 418 TAEGSHAGHIPDPPAIGRCCPAASPRGRWLWTWRPHCEPHLLLRGLNIADPVSLSRSECP 477
AEG G P++G + RGR L RP L L+G + S + + C
Sbjct: 235 AAEGPARG----TPSVGSLWKRRA-RGRQLN--RPWGRARLALQGAPPSRGTSAATAACT 287
Query: 478 GHVPLAEAALVTRTC 492
G A A + R C
Sbjct: 288 GRARAARAVSLPRAC 302
>gi|239751791 PREDICTED: hypothetical protein [Homo sapiens]
Length = 650
Score = 40.4 bits (93), Expect = 0.005
Identities = 48/180 (26%), Positives = 61/180 (33%), Gaps = 25/180 (13%)
Query: 161 RAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGP 220
R +LK + TR G G A GEGG G ++ R
Sbjct: 130 RGSFLKLSSSRSTRGLVLGEGVGVG---------AGGEGGGEGAAGAASSLSERSSERVE 180
Query: 221 RQGSTDKHTERGVRVGAVREVPTSTQR-GGRVGAVR---------EVRTSTLER--GPRG 268
Q TD R R PTS++R GR G +R + R S+ R P
Sbjct: 181 LQSDTDDSDTRVAEGARPRPGPTSSRRPWGRAGGLRPRGKRPARGKKRPSSQRRCSSPSA 240
Query: 269 PRQGSTDKHTERGPRGRRQ-GSADKHTERGPRGRRQGSADG---NHSEAPAHSPGGSDNQ 324
R +T P Q SA R P R G ADG + + AP GS +
Sbjct: 241 ARASATSAPRPTAPSSVAQPSSARSQRRRAPCPHRAGGADGVGSHGARAPGEGSAGSGTE 300
Score = 30.4 bits (67), Expect = 4.8
Identities = 41/155 (26%), Positives = 47/155 (30%), Gaps = 32/155 (20%)
Query: 179 AHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRG--PRQGSTDKHTE------ 230
A GEG +G R Q TD R G PR G T
Sbjct: 155 AGGEGGGEGAAGAASSLSERSSERVELQSDTDDSDTRVAEGARPRPGPTSSRRPWGRAGG 214
Query: 231 ---RGVRVGAVREVPTSTQRGGRVGAVREVRTST------------------LERGPRGP 269
RG R ++ P+S +R A R TS R P
Sbjct: 215 LRPRGKRPARGKKRPSSQRRCSSPSAARASATSAPRPTAPSSVAQPSSARSQRRRAPCPH 274
Query: 270 RQGSTDKHTERGPRGRRQGSADKHTER---GPRGR 301
R G D G R +GSA TER GP R
Sbjct: 275 RAGGADGVGSHGARAPGEGSAGSGTERVELGPHVR 309
>gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo
sapiens]
Length = 725
Score = 40.4 bits (93), Expect = 0.005
Identities = 48/180 (26%), Positives = 61/180 (33%), Gaps = 25/180 (13%)
Query: 161 RAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGP 220
R +LK + TR G G A GEGG G ++ R
Sbjct: 130 RGSFLKLSSSRSTRGLVLGEGVGVG---------AGGEGGGEGAAGAASSLSERSSERVE 180
Query: 221 RQGSTDKHTERGVRVGAVREVPTSTQR-GGRVGAVR---------EVRTSTLER--GPRG 268
Q TD R R PTS++R GR G +R + R S+ R P
Sbjct: 181 LQSDTDDSDTRVAEGARPRPGPTSSRRPWGRAGGLRPRGKRPARGKKRPSSQRRCSSPSA 240
Query: 269 PRQGSTDKHTERGPRGRRQ-GSADKHTERGPRGRRQGSADG---NHSEAPAHSPGGSDNQ 324
R +T P Q SA R P R G ADG + + AP GS +
Sbjct: 241 ARASATSAPRPTAPSSVAQPSSARSQRRRAPCPHRAGGADGVGSHGARAPGEGSAGSGTE 300
Score = 30.4 bits (67), Expect = 4.8
Identities = 41/155 (26%), Positives = 47/155 (30%), Gaps = 32/155 (20%)
Query: 179 AHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRG--PRQGSTDKHTE------ 230
A GEG +G R Q TD R G PR G T
Sbjct: 155 AGGEGGGEGAAGAASSLSERSSERVELQSDTDDSDTRVAEGARPRPGPTSSRRPWGRAGG 214
Query: 231 ---RGVRVGAVREVPTSTQRGGRVGAVREVRTST------------------LERGPRGP 269
RG R ++ P+S +R A R TS R P
Sbjct: 215 LRPRGKRPARGKKRPSSQRRCSSPSAARASATSAPRPTAPSSVAQPSSARSQRRRAPCPH 274
Query: 270 RQGSTDKHTERGPRGRRQGSADKHTER---GPRGR 301
R G D G R +GSA TER GP R
Sbjct: 275 RAGGADGVGSHGARAPGEGSAGSGTERVELGPHVR 309
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 39.3 bits (90), Expect = 0.010
Identities = 63/248 (25%), Positives = 94/248 (37%), Gaps = 22/248 (8%)
Query: 158 RARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYR--QAHGEGGPRGPHQGSTDKHTER 215
R R E K+ P++ A GS +PS + Q E P S TE+
Sbjct: 151 RGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK 210
Query: 216 GPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTD 275
R P+Q G R G+ R P++ Q+ R E + RG R T+
Sbjct: 211 --RKPQQPQCRPAGGTGQRRGS-RSSPSADQQ--RAQDREEEAAAAPAPTSRGHR---TE 262
Query: 276 KHTERGPRGRRQGSADKHTERG--PRGRRQGSADGNHSEAPAHSPGGSDNQINCR-HLEL 332
K + P+ R G + G P +QG+ D A A +P S ++ R L+L
Sbjct: 263 KRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQL 322
Query: 333 SRPRGGGLVHTRPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPR-EQAQDTH 391
GG R S +S +Q Q R + +A A V ++ R E+ +
Sbjct: 323 QCQPAGGTGQRRGSGC------SSSANQQGAQDREEEAA--AAPVPTSSGHRTEKRKPQQ 374
Query: 392 PTREGSGG 399
P R + G
Sbjct: 375 PQRRPAAG 382
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 39.3 bits (90), Expect = 0.010
Identities = 38/178 (21%), Positives = 65/178 (36%), Gaps = 7/178 (3%)
Query: 151 RKGAGELRARRAEYLKQTPPE---KTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQG 207
+KG+ + + A + P+ + + + A G + +PS RQ R P
Sbjct: 3722 KKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSS--RQIPSGAASRQPQ-- 3777
Query: 208 STDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPR 267
+ + G + P+Q T ++ + P ++Q G+ T GP
Sbjct: 3778 TQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP 3837
Query: 268 GPRQGSTDKHTERGPRGRRQGSADKHTERGPRGRRQGSADGNHSEAPAHSPGGSDNQI 325
Q + K T + P+ R A GP G + G+ G APA PG +
Sbjct: 3838 RAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESV 3895
Score = 32.7 bits (73), Expect = 0.96
Identities = 58/251 (23%), Positives = 87/251 (34%), Gaps = 18/251 (7%)
Query: 65 PEPDRSHGLTGSGKVSPGLPQAHPQVDSRTTAQ-QVTRVAVAVSTRPALPLPLPEGSKRS 123
P R+ G +G+ + G P+ QVDSRT + V+ + P P +P+ +
Sbjct: 109 PRETRAQG--PAGQEADG-PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLP 165
Query: 124 LWEPVNLVVSVSLDTVGDEMAF--CKRSRRKGAGELRARRAEYLKQTPPEKTRACR--QA 179
+ + L + + F C + K + +L Q C+ +A
Sbjct: 166 SSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRA 225
Query: 180 HGEGSAWAPSGK-YRQAHGEG-----GPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGV 233
G AP K +Q H P G D+ RGP GP+ GS T R
Sbjct: 226 LGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARAT 285
Query: 234 RVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKH 293
V + + GRV T PR P + K P G A +
Sbjct: 286 SVPGPAQA-AAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGL---GATEQ 341
Query: 294 TERGPRGRRQG 304
T+ G G+ G
Sbjct: 342 TQEGLTGKLFG 352
>gi|239757898 PREDICTED: similar to testis expressed sequence 13A
[Homo sapiens]
Length = 652
Score = 38.9 bits (89), Expect = 0.013
Identities = 44/177 (24%), Positives = 68/177 (38%), Gaps = 22/177 (12%)
Query: 192 YRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRV 251
+R++H GP GP QG+ + R ++G +D+ E V R P +R
Sbjct: 388 FRRSHKSEGPEGP-QGTVPQGDSRSYS--QEGCSDRAQEMATLVFIRRCKPEGPKRPQWT 444
Query: 252 GAVREVRTSTLERGPRGPR----QGSTDKHTERGPRGRRQG------SADKHTERGPRGR 301
+ + R+ E GP GP+ QG +++ G R QG S E GP
Sbjct: 445 VPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMATLVFSRSCKPEEGPERP 504
Query: 302 RQGSADGNHSEAPAHSPGG-------SDNQINCRHLELSRPRGGGLVHTRPSNAAEP 351
+ + S P G DN+ + E SR R G+ S + +P
Sbjct: 505 QDTPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQ--EGSRERAQGMATLVFSRSCKP 559
>gi|239752412 PREDICTED: similar to testis expressed sequence 13A
[Homo sapiens]
Length = 652
Score = 38.9 bits (89), Expect = 0.013
Identities = 44/177 (24%), Positives = 68/177 (38%), Gaps = 22/177 (12%)
Query: 192 YRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRV 251
+R++H GP GP QG+ + R ++G +D+ E V R P +R
Sbjct: 388 FRRSHKSEGPEGP-QGTVPQGDSRSYS--QEGCSDRAQEMATLVFIRRCKPEGPKRPQWT 444
Query: 252 GAVREVRTSTLERGPRGPR----QGSTDKHTERGPRGRRQG------SADKHTERGPRGR 301
+ + R+ E GP GP+ QG +++ G R QG S E GP
Sbjct: 445 VPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMATLVFSRSCKPEEGPERP 504
Query: 302 RQGSADGNHSEAPAHSPGG-------SDNQINCRHLELSRPRGGGLVHTRPSNAAEP 351
+ + S P G DN+ + E SR R G+ S + +P
Sbjct: 505 QDTPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQ--EGSRERAQGMATLVFSRSCKP 559
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 38.9 bits (89), Expect = 0.013
Identities = 69/268 (25%), Positives = 91/268 (33%), Gaps = 54/268 (20%)
Query: 197 GEGGPRGPHQG---STDKHTER------GPRGP--RQGSTDKHTERGVRVGAVREVPTST 245
G GP+GP QG D H + GP GP QG G + + P
Sbjct: 654 GPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 713
Query: 246 QRGGRVGAVREVRTSTLERGPRGPR-----QGSTDKHTERGPRGRR--QGSADKHTERGP 298
Q G +G +GP GP+ QG +GP G R QG H +G
Sbjct: 714 Q--GHIG----------PQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGG 761
Query: 299 RGRR-------QGSADGNHSEAPAHSPGGSDNQ--------INCRHLELSRPR-GGGLVH 342
G + QG G + PG +NQ + E+ P GGL+
Sbjct: 762 PGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG 821
Query: 343 TRPSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLAV 402
P P +Q P +++ + P Q+Q P +GS G
Sbjct: 822 HGPQEMRGP------QEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPP 873
Query: 403 SGGGFGETEPQGGAWTAEGSHAGHIPDP 430
GG G PQG A G H P P
Sbjct: 874 QGGMQGPPGPQGQQNPARGPHPSQGPIP 901
Score = 34.3 bits (77), Expect = 0.33
Identities = 41/171 (23%), Positives = 66/171 (38%), Gaps = 18/171 (10%)
Query: 170 PEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHT 229
P++ R + +GS P + R G +GP QGS + G +GP ++
Sbjct: 830 PQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNP 889
Query: 230 ERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGP--RQGSTDKHTERGPRGRRQ 287
RG P +Q G + ++ +T L GPR P ++G + P +Q
Sbjct: 890 ARG---------PHPSQ--GPI-PFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQ 937
Query: 288 GSADKHTERGPRGRRQGSADGNHSEAPAHSPGGSDNQINCRHLELSRPRGG 338
G+ + P G+ G G+ P H G + RH + P G
Sbjct: 938 GAQGRIPPLNP-GQGPGPNKGDSRGPPNHHMGPMSER---RHEQSGGPEHG 984
Score = 32.0 bits (71), Expect = 1.6
Identities = 40/147 (27%), Positives = 48/147 (32%), Gaps = 14/147 (9%)
Query: 181 GEGSAWAPSGK-YRQAHGEGGPRGPHQGSTDKHT--ERGPRGPRQGSTDKHTERGVRVGA 237
G G + P + + + G G RGP + ER PR P E R GA
Sbjct: 1049 GPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGA 1108
Query: 238 VREVPTSTQRGGRVGAVR------EVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSAD 291
GR G E E RG + T PRG R+G
Sbjct: 1109 PPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGT---PRGGRKGLLP 1165
Query: 292 KHTE--RGPRGRRQGSADGNHSEAPAH 316
E R GR+ S DGN P H
Sbjct: 1166 TPDEFPRFEGGRKPDSWDGNREPGPGH 1192
Score = 30.0 bits (66), Expect = 6.2
Identities = 37/155 (23%), Positives = 53/155 (34%), Gaps = 13/155 (8%)
Query: 156 ELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRG--PHQGSTDKHT 213
ELR +Q PP+ + G P G+ A G +G P Q
Sbjct: 851 ELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLL 910
Query: 214 ERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGS 273
GPR P + G G +P Q+G + G + + +G +G
Sbjct: 911 GDGPRAP-------FNQEGQSTGPPPLIPGLGQQGAQ-GRIPPLNPGQGPGPNKGDSRGP 962
Query: 274 TDKHTERGPRGRRQGSADKHTERGP-RGRRQGSAD 307
+ H GP R+ E GP RG +G D
Sbjct: 963 PNHH--MGPMSERRHEQSGGPEHGPERGPFRGGQD 995
>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
Length = 426
Score = 38.5 bits (88), Expect = 0.017
Identities = 72/296 (24%), Positives = 97/296 (32%), Gaps = 50/296 (16%)
Query: 80 SPGLPQAHPQVDSRTTAQQVTRVAVAVSTRPALPLPLPEGSKRSLWEPVNLVVSVSLDTV 139
+PG P+ PQ + A + P LP P ++ WE + V
Sbjct: 15 APGCPEVAPQPEGTDAPGPAVCSPTARAPPPILPAPQRPPTRAREWE--GAAWAAGATGV 72
Query: 140 GDEMAFCKRSRRKGAGELRARRAEYLKQTPPEKTR-ACRQAHGEGSAWAPSGKYRQAHGE 198
G + SRR G L R A + R +C + G APS ++
Sbjct: 73 GAALLALPGSRRLGRVPLTFREASPGPAPGAPRARGSCGREPGPRRRRAPSSAGKRPAAA 132
Query: 199 GGPRGPHQGSTDKHTER----------GPRGPRQGSTDKHTERGVRVGAVRE-VPTSTQR 247
P Q S + R GP PR +H R R R +P
Sbjct: 133 ARAAPPRQRSLARCLPRSVGSCVRPSVGPSLPR-----RHCRRHCRCHCRRRPLPKPPPL 187
Query: 248 GGRVGAVREVRTSTLERGPRGPRQG----STDKHTERGPRG------------------- 284
R+G+ R + G R P + ER P G
Sbjct: 188 QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGAR 247
Query: 285 RRQGSADKHTERGPRGRRQGSADGNHS-EAPAHSPGGSDNQINCRHLELSRPRGGG 339
RR+G ER RGRRQG A G+ A +PG + + R R RGGG
Sbjct: 248 RRRGG----EERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQW---RKRGGG 296
>gi|169216868 PREDICTED: similar to testis expressed sequence 13A
[Homo sapiens]
Length = 714
Score = 38.5 bits (88), Expect = 0.017
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 7/103 (6%)
Query: 192 YRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRV 251
+R++H GP GP QG+ + R ++G +D+ E V R P +R
Sbjct: 388 FRRSHKSEGPEGP-QGTVPQGDSRSYS--QEGCSDRAQEMATLVFIRRCKPEGPKRPQWT 444
Query: 252 GAVREVRTSTLERGPRGPR----QGSTDKHTERGPRGRRQGSA 290
+ + R+ E GP GP+ QG +++ G R QG A
Sbjct: 445 VPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMA 487
>gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo
sapiens]
Length = 334
Score = 38.1 bits (87), Expect = 0.023
Identities = 62/230 (26%), Positives = 83/230 (36%), Gaps = 38/230 (16%)
Query: 190 GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERG-VRVGAV-REVPTSTQR 247
G R E P P +G +K + R PR + TERG V GA +E P
Sbjct: 31 GDRRGLGREAAPGAPAEGEKEKG--KNSRRPRPTCSRGRTERGRVERGADHQERPAGAPA 88
Query: 248 GGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGP-RGRRQGSA 306
V A + + + R R R + + ERG R R+G R RGRR
Sbjct: 89 HRPVPAAAAILRAAVHRVLRVLRAAAAVRDAERGLR--REGPRRHAPPRKQLRGRR---- 142
Query: 307 DGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWT------ASHHSQ 360
G+ ++ HL PRGGGL P+ PL T S S
Sbjct: 143 -------------GAAGLVSAGHLGREPPRGGGL--RPPALVPVPLATPLLLEGRSEPST 187
Query: 361 SALQQRPDHSAVMCAHVDSTP------TPREQAQDTHPTREGSGGLAVSG 404
A +A++ AHV P PR + + G G A +G
Sbjct: 188 RACAVSGGQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRGAAAG 237
>gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo
sapiens]
Length = 329
Score = 38.1 bits (87), Expect = 0.023
Identities = 62/230 (26%), Positives = 83/230 (36%), Gaps = 38/230 (16%)
Query: 190 GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERG-VRVGAV-REVPTSTQR 247
G R E P P +G +K + R PR + TERG V GA +E P
Sbjct: 26 GDRRGLGREAAPGAPAEGEKEKG--KNSRRPRPTCSRGRTERGRVERGADHQERPAGAPA 83
Query: 248 GGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGP-RGRRQGSA 306
V A + + + R R R + + ERG R R+G R RGRR
Sbjct: 84 HRPVPAAAAILRAAVHRVLRVLRAAAAVRDAERGLR--REGPRRHAPPRKQLRGRR---- 137
Query: 307 DGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWT------ASHHSQ 360
G+ ++ HL PRGGGL P+ PL T S S
Sbjct: 138 -------------GAAGLVSAGHLGREPPRGGGL--RPPALVPVPLATPLLLEGRSEPST 182
Query: 361 SALQQRPDHSAVMCAHVDSTP------TPREQAQDTHPTREGSGGLAVSG 404
A +A++ AHV P PR + + G G A +G
Sbjct: 183 RACAVSGGQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRGAAAG 232
>gi|239508758 PREDICTED: hypothetical protein [Homo sapiens]
Length = 329
Score = 38.1 bits (87), Expect = 0.023
Identities = 62/230 (26%), Positives = 83/230 (36%), Gaps = 38/230 (16%)
Query: 190 GKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERG-VRVGAV-REVPTSTQR 247
G R E P P +G +K + R PR + TERG V GA +E P
Sbjct: 26 GDRRGLGREAAPGAPAEGEKEKG--KNSRRPRPTCSRGRTERGRVERGADHQERPAGAPA 83
Query: 248 GGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTERGP-RGRRQGSA 306
V A + + + R R R + + ERG R R+G R RGRR
Sbjct: 84 HRPVPAAAAILRAAVHRVLRVLRAAAAVRDAERGLR--REGPRRHAPPRKQLRGRR---- 137
Query: 307 DGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEPLWT------ASHHSQ 360
G+ ++ HL PRGGGL P+ PL T S S
Sbjct: 138 -------------GAAGLVSAGHLGREPPRGGGL--RPPALVPVPLATPLLLEGRSEPST 182
Query: 361 SALQQRPDHSAVMCAHVDSTP------TPREQAQDTHPTREGSGGLAVSG 404
A +A++ AHV P PR + + G G A +G
Sbjct: 183 RACAVSGGQAALLGAHVRPAPDRAARCAPRAKKAGANAGARGQGRGAAAG 232
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
[Homo sapiens]
Length = 1736
Score = 38.1 bits (87), Expect = 0.023
Identities = 50/199 (25%), Positives = 64/199 (32%), Gaps = 27/199 (13%)
Query: 167 QTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGG------PRGPHQGSTDKHTERGPRGP 220
Q PP R + +GEG P G Y +G G GP + H+ GP
Sbjct: 319 QVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGP 378
Query: 221 RQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLERGPRG--PRQGSTDKHT 278
R +K + G + E P + G G + GP G G
Sbjct: 379 RGLKGEKGEPAVLEPGMLVEGPPGPE--GPAGLI----------GPPGIQGNPGPVGDPG 426
Query: 279 ERGPRGRRQGSADKHTERGPRGR------RQGSADGNHSEAPAHSPGGSDNQINCRHLEL 332
ERGP G R G GP G R GS G+ A + + L L
Sbjct: 427 ERGPPG-RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 485
Query: 333 SRPRGGGLVHTRPSNAAEP 351
P G RP +P
Sbjct: 486 RGPPGPMGYTGRPGPLGQP 504
Score = 37.7 bits (86), Expect = 0.030
Identities = 46/135 (34%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 195 AHGEGGPRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPT-STQRGGRVGA 253
+ GE GP GP +G T + GP G G K G+ R+ P S G GA
Sbjct: 764 SRGEDGPEGP-KGRTGPTGDPGPPG-LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGA 821
Query: 254 VRE--VRTSTLERGPRGPRQGSTDKHTERGPRGRRQGSADKHTE-----RGPRGRR--QG 304
E R + + GPRG R G T +RGPRG S K T GP G R G
Sbjct: 822 SGEKGARGLSGKSGPRGER-GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG 880
Query: 305 SADGNHSEAPAHSPG 319
N P PG
Sbjct: 881 PQGPNGFPGPKGPPG 895
Score = 31.6 bits (70), Expect = 2.1
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 13/66 (19%)
Query: 265 GPRGPRQGSTDKHTERGPRGRR-----------QGSADKHTERGPRGRRQGSADGNHSEA 313
GP+GP+ GS E GP G++ QG+ H E+GP+G + G S+
Sbjct: 631 GPQGPK-GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG-KPGLPGMPGSDG 688
Query: 314 PAHSPG 319
P PG
Sbjct: 689 PPGHPG 694
>gi|239749325 PREDICTED: hypothetical protein [Homo sapiens]
Length = 155
Score = 37.7 bits (86), Expect = 0.030
Identities = 50/177 (28%), Positives = 65/177 (36%), Gaps = 32/177 (18%)
Query: 232 GVRVGA--VREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGS 289
GV VGA + ST GR +VR T+ R GP G+ D G + R GS
Sbjct: 4 GVGVGAAGLGAAHRSTAAPGRGVSVR----GTVGRQQGGPGHGNVDHLPNLGRQPRGAGS 59
Query: 290 ADKHTERGPRGRRQGSA-----DGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTR 344
PR R G+A H + + + R L R RGGG +R
Sbjct: 60 RGASA---PRAVRTGAAPEVVVQSGHRSHASKRRFLEEGEAPARRLS-ERRRGGGKEESR 115
Query: 345 PSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLA 401
P AA P A + ++A P RE A+ TH R G+A
Sbjct: 116 PGTAAAPGGRAGLYPRAA-----------------GPASREPARPTHRPRAPPRGVA 155
>gi|239509122 PREDICTED: hypothetical protein [Homo sapiens]
Length = 155
Score = 37.7 bits (86), Expect = 0.030
Identities = 50/177 (28%), Positives = 65/177 (36%), Gaps = 32/177 (18%)
Query: 232 GVRVGA--VREVPTSTQRGGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPRGRRQGS 289
GV VGA + ST GR +VR T+ R GP G+ D G + R GS
Sbjct: 4 GVGVGAAGLGAAHRSTAAPGRGVSVR----GTVGRQQGGPGHGNVDHLPNLGRQPRGAGS 59
Query: 290 ADKHTERGPRGRRQGSA-----DGNHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTR 344
PR R G+A H + + + R L R RGGG +R
Sbjct: 60 RGASA---PRAVRTGAAPEVVVQSGHRSHASKRRFLEEGEAPARRLS-ERRRGGGKEESR 115
Query: 345 PSNAAEPLWTASHHSQSALQQRPDHSAVMCAHVDSTPTPREQAQDTHPTREGSGGLA 401
P AA P A + ++A P RE A+ TH R G+A
Sbjct: 116 PGTAAAPGGRAGLYPRAA-----------------GPASREPARPTHRPRAPPRGVA 155
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 37.7 bits (86), Expect = 0.030
Identities = 40/161 (24%), Positives = 54/161 (33%), Gaps = 9/161 (5%)
Query: 169 PP--EKTRACRQAHGEGSAWAPSGKYRQAHGEGGPRGPHQGSTDKHTERGPRGPRQGSTD 226
PP +K+R R+ GE A S Q P P + +R P S
Sbjct: 513 PPTRKKSRRERKRSGEAKEAASSSSGTQP-APPAPASPWDSKKHRSRDRKPGSHASSSAR 571
Query: 227 KHTERGVRVGAVREVPTSTQR---GGRVGAVREVRTSTLERGPRGPRQGSTDKHTERGPR 283
+ + R + R ST R G R RE R P S+ R
Sbjct: 572 RRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHR 631
Query: 284 GRRQ---GSADKHTERGPRGRRQGSADGNHSEAPAHSPGGS 321
G+ + GS K RG ++ + APA P GS
Sbjct: 632 GKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGS 672
Score = 31.6 bits (70), Expect = 2.1
Identities = 51/223 (22%), Positives = 68/223 (30%), Gaps = 36/223 (16%)
Query: 149 SRRKGAGELRARRAEYLKQTPPEKTRACRQAHGEGSAWAPSGKYRQAHGEGG-------- 200
SRR + E R RR +PP T + + E ++R H +GG
Sbjct: 597 SRRSRSREKRRRRRR--SASPPPATSSSSSSRRE--------RHRGKHRDGGGSKKKKKR 646
Query: 201 --PRGPHQGSTDKHTERGPRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVR 258
RG + P P GST R GA VP S Q R
Sbjct: 647 SRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGA---VPPSIQDLTDHDLFAIKR 703
Query: 259 TSTLER----GPRGPRQGSTDK------HTERGPRGRRQGSADKHTERGPRGRRQGSADG 308
T T+ R PRGP + G G +G +R G S+
Sbjct: 704 TITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSS 763
Query: 309 NHSEAPAHSPGGSDNQINCRHLELSRPRGGGLVHTRPSNAAEP 351
+ + G D R + R R RP + P
Sbjct: 764 REKGSRRKALDGGDRD---RDRDRDRDRDRSSKKARPPKESAP 803
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,575,929
Number of Sequences: 37866
Number of extensions: 1742850
Number of successful extensions: 6230
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 255
Number of HSP's that attempted gapping in prelim test: 5657
Number of HSP's gapped (non-prelim): 645
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.