Guide to the Human Genome
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Search of human proteins with 116268127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116268127 kinase non-catalytic C-lobe domain (KIND)
containing 1 isoform a [Homo sapiens]
         (1749 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...  3522   0.0  
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     65   4e-10
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    64   1e-09
gi|54860079 nadrin isoform 1 [Homo sapiens]                            63   3e-09
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    63   3e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    62   5e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    62   5e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    62   6e-09
gi|54860105 nadrin isoform 2 [Homo sapiens]                            59   3e-08
gi|150170670 piccolo isoform 2 [Homo sapiens]                          59   4e-08
gi|150378539 piccolo isoform 1 [Homo sapiens]                          59   4e-08
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    59   4e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   5e-08
gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Hom...    58   7e-08
gi|33286446 opioid growth factor receptor [Homo sapiens]               58   9e-08
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  57   1e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      57   1e-07
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    57   1e-07
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof...    57   2e-07
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof...    57   2e-07
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    57   2e-07
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    57   2e-07
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    57   2e-07
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    57   2e-07
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    57   2e-07
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    57   2e-07
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    57   2e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    56   3e-07
gi|188536004 zinc finger protein 469 [Homo sapiens]                    56   3e-07
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       56   3e-07

>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
            isoform a [Homo sapiens]
          Length = 1749

 Score = 3522 bits (9132), Expect = 0.0
 Identities = 1749/1749 (100%), Positives = 1749/1749 (100%)

Query: 1    MQAMDPAAADLYEEDGKDLDFYDFEPLPTLPEDEENVSLADILSLRDRGLSEQEAWAVCL 60
            MQAMDPAAADLYEEDGKDLDFYDFEPLPTLPEDEENVSLADILSLRDRGLSEQEAWAVCL
Sbjct: 1    MQAMDPAAADLYEEDGKDLDFYDFEPLPTLPEDEENVSLADILSLRDRGLSEQEAWAVCL 60

Query: 61   ECSLSMRSVAHAAIFQSLCITPDTLAFNTSGNVCFMEQLSDDPEGAFVPPEFDVTGNTFE 120
            ECSLSMRSVAHAAIFQSLCITPDTLAFNTSGNVCFMEQLSDDPEGAFVPPEFDVTGNTFE
Sbjct: 61   ECSLSMRSVAHAAIFQSLCITPDTLAFNTSGNVCFMEQLSDDPEGAFVPPEFDVTGNTFE 120

Query: 121  AHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQ 180
            AHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQ
Sbjct: 121  AHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQ 180

Query: 181  LTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVL 240
            LTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVL
Sbjct: 181  LTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVL 240

Query: 241  PTPEGPESETSRGPRASPTKALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRS 300
            PTPEGPESETSRGPRASPTKALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRS
Sbjct: 241  PTPEGPESETSRGPRASPTKALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRS 300

Query: 301  RLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPDPRKAFLDRKNGLSSFQAQPK 360
            RLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPDPRKAFLDRKNGLSSFQAQPK
Sbjct: 301  RLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPDPRKAFLDRKNGLSSFQAQPK 360

Query: 361  CRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADPRDASGEAQ 420
            CRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADPRDASGEAQ
Sbjct: 361  CRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADPRDASGEAQ 420

Query: 421  TPRDDERIPEGARQLESAAAEQWVSLQDLLSQLGRPFREYELWALCLACLRALQTRPEHP 480
            TPRDDERIPEGARQLESAAAEQWVSLQDLLSQLGRPFREYELWALCLACLRALQTRPEHP
Sbjct: 421  TPRDDERIPEGARQLESAAAEQWVSLQDLLSQLGRPFREYELWALCLACLRALQTRPEHP 480

Query: 481  AYLCLDSVLVAEDGAVLFQPPPANGSYDSFFLAPELAEERLVTEKASVYCVAAVLWTAAK 540
            AYLCLDSVLVAEDGAVLFQPPPANGSYDSFFLAPELAEERLVTEKASVYCVAAVLWTAAK
Sbjct: 481  AYLCLDSVLVAEDGAVLFQPPPANGSYDSFFLAPELAEERLVTEKASVYCVAAVLWTAAK 540

Query: 541  FSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRA 600
            FSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRA
Sbjct: 541  FSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRA 600

Query: 601  SICQVYQEEETISLQNAFSVVELKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCG 660
            SICQVYQEEETISLQNAFSVVELKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCG
Sbjct: 601  SICQVYQEEETISLQNAFSVVELKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCG 660

Query: 661  EEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAH 720
            EEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAH
Sbjct: 661  EEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAH 720

Query: 721  AGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS 780
            AGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS
Sbjct: 721  AGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS 780

Query: 781  PVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERP 840
            PVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERP
Sbjct: 781  PVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERP 840

Query: 841  GQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATRLI 900
            GQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATRLI
Sbjct: 841  GQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATRLI 900

Query: 901  QEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCDLYWDEKLLQNLFKVVN 960
            QEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCDLYWDEKLLQNLFKVVN
Sbjct: 901  QEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCDLYWDEKLLQNLFKVVN 960

Query: 961  GQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMARTSSRAPCSPTSVSDV 1020
            GQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMARTSSRAPCSPTSVSDV
Sbjct: 961  GQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMARTSSRAPCSPTSVSDV 1020

Query: 1021 DSDALSRGNFEVGFRPQRSVKAERAQQPEAGEDRRPAGGASDVEAVTRLARSKGVGPALS 1080
            DSDALSRGNFEVGFRPQRSVKAERAQQPEAGEDRRPAGGASDVEAVTRLARSKGVGPALS
Sbjct: 1021 DSDALSRGNFEVGFRPQRSVKAERAQQPEAGEDRRPAGGASDVEAVTRLARSKGVGPALS 1080

Query: 1081 PGPAGFQSCSPGWCSAFYEADCFGADVHNYVKDLGRQQADGALPDAQSPELEQQLMMEKR 1140
            PGPAGFQSCSPGWCSAFYEADCFGADVHNYVKDLGRQQADGALPDAQSPELEQQLMMEKR
Sbjct: 1081 PGPAGFQSCSPGWCSAFYEADCFGADVHNYVKDLGRQQADGALPDAQSPELEQQLMMEKR 1140

Query: 1141 NYRKTLKFYQKLLQKEKRNKGSDVKTMLSKLKGQLEEMKSRVQFLSLVKKYLQVMYAERW 1200
            NYRKTLKFYQKLLQKEKRNKGSDVKTMLSKLKGQLEEMKSRVQFLSLVKKYLQVMYAERW
Sbjct: 1141 NYRKTLKFYQKLLQKEKRNKGSDVKTMLSKLKGQLEEMKSRVQFLSLVKKYLQVMYAERW 1200

Query: 1201 GLEPCTLPVIVNIAAAPCDTLDFSPLDESSSLIFYNVNKHPGGRQKARILQAGTPLGLMA 1260
            GLEPCTLPVIVNIAAAPCDTLDFSPLDESSSLIFYNVNKHPGGRQKARILQAGTPLGLMA
Sbjct: 1201 GLEPCTLPVIVNIAAAPCDTLDFSPLDESSSLIFYNVNKHPGGRQKARILQAGTPLGLMA 1260

Query: 1261 YLYSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSL 1320
            YLYSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSL
Sbjct: 1261 YLYSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSL 1320

Query: 1321 CVLQAWVEDCYAVDFPRNSGLLGKLEDFISSKILPLDGSAKHLLGLLEVGMDRRAEGNPR 1380
            CVLQAWVEDCYAVDFPRNSGLLGKLEDFISSKILPLDGSAKHLLGLLEVGMDRRAEGNPR
Sbjct: 1321 CVLQAWVEDCYAVDFPRNSGLLGKLEDFISSKILPLDGSAKHLLGLLEVGMDRRAEGNPR 1380

Query: 1381 GTDLENPREAEEDARPFNALCKRLSEDGISRKSFPWRLPRGNGLVLPPHKERPYTIAAAL 1440
            GTDLENPREAEEDARPFNALCKRLSEDGISRKSFPWRLPRGNGLVLPPHKERPYTIAAAL
Sbjct: 1381 GTDLENPREAEEDARPFNALCKRLSEDGISRKSFPWRLPRGNGLVLPPHKERPYTIAAAL 1440

Query: 1441 PKPCFLEDFYGPCAKTSEKGPYFLTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSRALGV 1500
            PKPCFLEDFYGPCAKTSEKGPYFLTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSRALGV
Sbjct: 1441 PKPCFLEDFYGPCAKTSEKGPYFLTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSRALGV 1500

Query: 1501 MDKSTAIPKASSSESLSAKTCSLFLPNYVQDKYLLQLLRNADDVSTWVAAEIVTSHTSKL 1560
            MDKSTAIPKASSSESLSAKTCSLFLPNYVQDKYLLQLLRNADDVSTWVAAEIVTSHTSKL
Sbjct: 1501 MDKSTAIPKASSSESLSAKTCSLFLPNYVQDKYLLQLLRNADDVSTWVAAEIVTSHTSKL 1560

Query: 1561 QVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQSPAWRILPAKIAEVMEELKAVE 1620
            QVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQSPAWRILPAKIAEVMEELKAVE
Sbjct: 1561 QVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQSPAWRILPAKIAEVMEELKAVE 1620

Query: 1621 VFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLETGGFTMTNGAHRWSKLRNIAKVVS 1680
            VFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLETGGFTMTNGAHRWSKLRNIAKVVS
Sbjct: 1621 VFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLETGGFTMTNGAHRWSKLRNIAKVVS 1680

Query: 1681 QVHAFQENPYTFSPDPKLQSYLKQRIARFSGADISTLAADSRANFHQVSSEKHSRKIQDK 1740
            QVHAFQENPYTFSPDPKLQSYLKQRIARFSGADISTLAADSRANFHQVSSEKHSRKIQDK
Sbjct: 1681 QVHAFQENPYTFSPDPKLQSYLKQRIARFSGADISTLAADSRANFHQVSSEKHSRKIQDK 1740

Query: 1741 LRRMKATFQ 1749
            LRRMKATFQ
Sbjct: 1741 LRRMKATFQ 1749


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 72/256 (28%), Positives = 86/256 (33%), Gaps = 30/256 (11%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P     P P  G    N   G    PG   G  P G    Q P           P     
Sbjct: 177 PGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKPQGPPPQGDN 230

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPE 744
            +  AR  P   Q    + G Q +G        +        K P GP P   PQG  P 
Sbjct: 231 KSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQG--PP 287

Query: 745 PLGASVQRDSAQ--GRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQG--PAE 800
           P G S  R S    G+P  PP    NQP+G          P PP K    P + G  P  
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGGNKPQG 338

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQ------EPEGPGATPAGE 854
           P PPG   G          +A   P  P  PP+ +     G        P+ P A PAG+
Sbjct: 339 PPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 398

Query: 855 RDDQSPDSVPERPRPA 870
              Q P   P+  RP+
Sbjct: 399 --PQGPPRPPQGGRPS 412



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 71/262 (27%), Positives = 86/262 (32%), Gaps = 27/262 (10%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P     P P  G    N   G    PG   G  P G    Q P           P     
Sbjct: 115 PGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNKPQGPPP---PGKPQGPPPQGD 167

Query: 685 NAS-VARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAP 743
           N S  +R  P   Q    + G Q +G        +        K P GP P   PQG  P
Sbjct: 168 NKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQGPPP 226

Query: 744 EPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPP---TKASALPVEQGPAE 800
           +    S    S  G+P  PP    NQP+G     PG P   PP    K    P    P  
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285

Query: 801 PIPPGVASGGLRPDALG-----PTTAHHGPRHPPKPPRSKATERP--GQEPEGP------ 847
           P P G +         G     P    + P+ PP PP       P  G +P+GP      
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345

Query: 848 -GATPAGERDDQSPDSVPERPR 868
            G  P G    +S  S P +P+
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQ 367



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 52/168 (30%), Positives = 64/168 (38%), Gaps = 41/168 (24%)

Query: 729 PDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTK 788
           P GP P   PQG  P+   +   R S  G+P  PP    NQP+G        P P PP K
Sbjct: 89  PQGPPPPGKPQGPPPQGDKSRSPR-SPPGKPQGPPPQGGNQPQG--------P-PPPPGK 138

Query: 789 ASALPVEQG--PAEPIPPGVASGGLRPDALG-----------------PTTAHHGPRHPP 829
               P + G  P  P PPG   G   P   G                 P    + P+ PP
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP 195

Query: 830 KPPRSKATERP--GQEPEGP-------GATPAGERDDQSPDSVPERPR 868
            PP       P  G +P+GP       G  P G+   QS  S P +P+
Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 26/164 (15%)

Query: 721 AGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS 780
           AG+P    P G     GP     +P G   Q  +    P PPP  P   P    +   G 
Sbjct: 33  AGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92

Query: 781 PVPAPPTKASALPVEQGP---AEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKAT 837
           P P  P      P  QG    +   PPG   G        P    + P+ PP PP     
Sbjct: 93  PPPGKPQG----PPPQGDKSRSPRSPPGKPQG-------PPPQGGNQPQGPPPPPGKPQG 141

Query: 838 ERP--GQEPEGP-------GATPAGE---RDDQSPDSVPERPRP 869
             P  G +P+GP       G  P G+   R  +SP   P+ P P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 40/131 (30%), Positives = 51/131 (38%), Gaps = 19/131 (14%)

Query: 738 PQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQG 797
           P   A  P GA  Q  +    P  PP  P   P    +   G   P PP K       QG
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP--PPPPGK------PQG 80

Query: 798 PAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDD 857
           P    PP    GG +P    P     GP  PP+  +S++   P  +P+GP   P G    
Sbjct: 81  P----PP---QGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGP--PPQGGNQP 129

Query: 858 QSPDSVPERPR 868
           Q P   P +P+
Sbjct: 130 QGPPPPPGKPQ 140


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 58/180 (32%), Positives = 78/180 (43%), Gaps = 27/180 (15%)

Query: 729 PDGPVPGPG-PQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSP---VPA 784
           P GP P PG PQG  P+  G   Q     G+P  PP      P+G  S +P SP      
Sbjct: 108 PQGPPPPPGKPQGPPPQG-GNRPQGPPPPGKPQGPP------PQGDKSRSPRSPPGKPQG 160

Query: 785 PPTKASALPVEQGPAEPIPPG-----VASGGLRPDALGPTTAHHGPRHPPKPPRSKATER 839
           PP +    P  QGP  P PPG        GG +P    P     GP  PP+  +S++++ 
Sbjct: 161 PPPQGGNQP--QGP--PPPPGKPQGPPPQGGKKPQGPPPPGKPQGP--PPQGDKSRSSQS 214

Query: 840 PGQEPEGPGATPAGERDDQSPDSVPERPR-PADRRLCLPCVDASPLPGRTACPSLQEATR 898
           P  +P+GP   P G    Q P   P +P+ P  +    P     P PG+   P  Q  ++
Sbjct: 215 PPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKP--QGPPPPGKPQGPPAQGGSK 270



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 49/156 (31%), Positives = 65/156 (41%), Gaps = 16/156 (10%)

Query: 721 AGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS 780
           AG+P   +P G     GP     +P G   Q  +    P PP +     P+G  S +P S
Sbjct: 33  AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92

Query: 781 P---VPAPPTKASALPVEQGPAEPIPPG-----VASGGLRPDALGPTTAHHGPRHPPKPP 832
           P      PP +    P  QGP  P PPG        GG RP    P     GP  PP+  
Sbjct: 93  PPGKPQGPPPQGGNQP--QGP--PPPPGKPQGPPPQGGNRPQGPPPPGKPQGP--PPQGD 146

Query: 833 RSKATERPGQEPEGPGATPAGERDDQSPDSVPERPR 868
           +S++   P  +P+GP   P G    Q P   P +P+
Sbjct: 147 KSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQ 180



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 70/256 (27%), Positives = 85/256 (33%), Gaps = 32/256 (12%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P     P P  G    N   G    PG   G  P G    Q P           P     
Sbjct: 94  PGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNRPQGPPP---PGKPQGPPPQGD 146

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSL--KTPDGPVPGPGPQGAA 742
            +   R  P   Q    + G Q +G        +   G P    K P GP P   PQG  
Sbjct: 147 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---GPPPQGGKKPQGPPPPGKPQGPP 203

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQG--PAE 800
           P+    S    S  G+P  PP    NQP+G          P PP K    P + G  P  
Sbjct: 204 PQG-DKSRSSQSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGGNKPQG 253

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQ------EPEGPGATPAGE 854
           P PPG   G          +A   P  P  PP+ +     G        P+ P A PAG+
Sbjct: 254 PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313

Query: 855 RDDQSPDSVPERPRPA 870
              Q P   P+  RP+
Sbjct: 314 --PQGPPRPPQGGRPS 327



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 9/126 (7%)

Query: 723 SPSLKTPDGPVPGPGPQGA----APEPLGASVQRDSAQGRPCPPPQAPANQPEG--ASSA 776
           S S ++P G   GP PQG      P P     Q    QG   P    P  +P+G  A   
Sbjct: 209 SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG 268

Query: 777 APGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKA 836
           +      +PP K    P ++G     PP  A G  +     P      P+ PP+PP+   
Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ---PQGPPRPPQGGR 325

Query: 837 TERPGQ 842
             RP Q
Sbjct: 326 PSRPPQ 331



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 23/110 (20%)

Query: 763 PQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAH 822
           P   A  P+G S      P   PP         QGP    PP    GG +P    P    
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKP----QGP----PP---QGGNKPQGPPP---- 73

Query: 823 HGPRHPPKPP----RSKATERPGQEPEGPGATPAGERDDQSPDSVPERPR 868
             P  P  PP    +S++   P  +P+GP   P G    Q P   P +P+
Sbjct: 74  --PGKPQGPPPQGDKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQ 119


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 73/262 (27%), Positives = 96/262 (36%), Gaps = 53/262 (20%)

Query: 626 SVAPA-PEPSPGFLPVNSDTGLVAVP--------GPVPGQHPCGEEATQLPAAFTSEATH 676
           +V PA PEP P      S +G   VP        GP PG     +    + AA  +   +
Sbjct: 534 TVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRN 593

Query: 677 FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGP 736
              I   QN      QP  A    +   GQ             +A  PS  T    V  P
Sbjct: 594 NSQIASGQN------QPQAAAGSHQLSMGQPH-----------NAAGPSPHTLRRAVKKP 636

Query: 737 GPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVE- 795
            P  A P+P               PPP  P  Q    +S  P S  P PPT++ + P + 
Sbjct: 637 AP--APPKPGN-------------PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQH 681

Query: 796 --QGPAEPIPPGVASGGLR-PDALGPTTAHHGPRHPPKPPRSKA-----TERPGQEPEGP 847
             Q P +P  P   S   R   +L P  A   P HPP  P ++A     T+   Q P  P
Sbjct: 682 TGQPPGQPSAPSQLSAPRRYSSSLSPIQA---PNHPPPQPPTQATPLMHTKPNSQGPPNP 738

Query: 848 GATPAGERDDQSPDSVPERPRP 869
            A P+    +Q   + P+ P P
Sbjct: 739 MALPSEHGLEQPSHTPPQTPTP 760



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 50/212 (23%), Positives = 76/212 (35%), Gaps = 25/212 (11%)

Query: 706 QREGEGEEKLSLEAHAG---------SPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQ 756
           ++E  G + +  +AH           SP+ + P  P  G     A PEP   S + +S+ 
Sbjct: 494 KKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSS 553

Query: 757 GRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDAL 816
           G    P  A   + +G S      P P  P  A+     +  ++     +ASG  +P A 
Sbjct: 554 GGGTVPSSAGILE-QGPSPGDGSPPKPKDPVSAAVPAPGRNNSQ-----IASGQNQPQAA 607

Query: 817 GPT-----TAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPER----- 866
             +        H    P      +A ++P   P  PG  P G    QS     +      
Sbjct: 608 AGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLS 667

Query: 867 PRPADRRLCLPCVDASPLPGRTACPSLQEATR 898
           P+P  R    P       PG+ + PS   A R
Sbjct: 668 PKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPR 699


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 72/257 (28%), Positives = 92/257 (35%), Gaps = 42/257 (16%)

Query: 624 KPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
           +P     P P  G    N   G    PG   GQ P G   +Q P     +     P    
Sbjct: 74  RPGKPEGPPPQGG----NQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPP---- 125

Query: 684 QNASVARDQPALAQEESEERGGQREGE----GEEKLSLEAHAGSPSLKTPDG------PV 733
           Q  + ++  P         R G+ EG     G +        G P    P G      P 
Sbjct: 126 QGGNQSQGPPP--------RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 177

Query: 734 PGPG-PQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASAL 792
           P PG P+G  P+    S       G+P  PP    NQ +G     PG P   PP++    
Sbjct: 178 PHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR-PGKP-EGPPSQGGNK 235

Query: 793 PVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPA 852
           P  QGP  P  PG   G        P    + P+ PP P R +    PG  P+ P   PA
Sbjct: 236 P--QGP--PPHPGKPQGP-------PPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPA 284

Query: 853 GERDDQSPDSVPERPRP 869
           G+   Q P   P+  RP
Sbjct: 285 GK--PQGPPPPPQGGRP 299



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 59/235 (25%), Positives = 80/235 (34%), Gaps = 22/235 (9%)

Query: 679 PIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGP 738
           P V++      R Q     + +    G+ EG   +  + ++    P    P+GP P  G 
Sbjct: 29  PSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGN-QSQGPPPRPGKPEGPPPQGGN 87

Query: 739 QGAAPEPLGASVQRDSAQGR-----PCPPPQAPAN-QPEGASSAAPGSPVPAPPTKASAL 792
           Q   P P     +    QG      P P P  P    P+G + +    P P  P      
Sbjct: 88  QSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 147

Query: 793 PVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPK---PPRSKATE------RPGQE 843
              Q    P  PG   G   P   G   +   P HP K   PP     +      RPG +
Sbjct: 148 GGNQSQGPPPRPGKPEG---PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPG-K 203

Query: 844 PEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATR 898
           PEGP   P G    Q P   P +P     +         P PG+   P  QE  +
Sbjct: 204 PEGP--PPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNK 256



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 56/215 (26%), Positives = 75/215 (34%), Gaps = 21/215 (9%)

Query: 695 LAQEESE-----ERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGAS 749
           ++QEES      +  G+R   G +        G P  + P G     GP     +P G  
Sbjct: 23  VSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPP 82

Query: 750 VQRDSAQGRPCPPPQAPANQ-PEGASSA-----APGSPVPAPP---TKASALPVEQGPAE 800
            Q  +    P P P  P  Q P+G + +      PG P   PP    ++   P   G  E
Sbjct: 83  PQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 142

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGP-GATPAGERDDQS 859
             PP    GG    + GP      P  PP P     ++ P   P  P G  P G    Q 
Sbjct: 143 GPPP---QGG--NQSQGPPPRPGKPEGPP-PQGGNQSQGPPPHPGKPEGPPPQGGNQSQG 196

Query: 860 PDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQ 894
           P   P +P     +         P PG+   P  Q
Sbjct: 197 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQ 231



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 49/181 (27%), Positives = 60/181 (33%), Gaps = 13/181 (7%)

Query: 624 KPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
           +P     P P  G    N   G    PG   G  P G   +Q P     +     P    
Sbjct: 137 RPGKPEGPPPQGG----NQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGN 192

Query: 684 QNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSL--KTPDGPVPGPG-PQG 740
           Q+      +P   +    + G Q +G        E   G PS     P GP P PG PQG
Sbjct: 193 QSQGPP-PRPGKPEGPPPQGGNQSQGPPPRPGKPE---GPPSQGGNKPQGPPPHPGKPQG 248

Query: 741 AAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAE 800
             P+  G   QR    GRP  PP  P   P+       G P   PP      P      +
Sbjct: 249 PPPQE-GNKPQRPPPPGRPQGPP-PPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQ 306

Query: 801 P 801
           P
Sbjct: 307 P 307



 Score = 31.2 bits (69), Expect = 9.3
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 358 QPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADPRDASG 417
           QP+    P  +PE   GR P  G  +    G P  PG+PE   P  G       PR    
Sbjct: 46  QPQRTPPPPGKPE---GRPPQGGNQSQ---GPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 99

Query: 418 EAQTPR 423
           E Q P+
Sbjct: 100 EGQPPQ 105


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 81/305 (26%), Positives = 105/305 (34%), Gaps = 44/305 (14%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P ++P   P P   P  +   L A P P P   P    AT  P A  + A H      + 
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSP 442

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA----GSPSLKTPDGPVPGPGPQG 740
             S     P  +   S           +   SL A       SP    P  P   P PQ 
Sbjct: 443 PPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ- 500

Query: 741 AAPEPLGA--------------SVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPP 786
            AP PL A              ++     Q  P PP   P   P   S++ P SP+  PP
Sbjct: 501 -APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559

Query: 787 TKAS---ALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPR--------HPPKPPRSK 835
            +A    A P+ Q P  P          RP   GP T+  GPR         PP P RS 
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619

Query: 836 ATERPGQEPEGPGATPAGERDD-QSPDSVPE------RPRPADRRLCLPCV----DASPL 884
           ++   G +  G  ++     ++ +  DS PE       P  A+   C P       A PL
Sbjct: 620 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 679

Query: 885 PGRTA 889
             R A
Sbjct: 680 AFRGA 684



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 81/300 (27%), Positives = 102/300 (34%), Gaps = 48/300 (16%)

Query: 628 APAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNAS 687
           A  PE +P   P  S       P   P     GE A   PA  TS      P    + + 
Sbjct: 68  ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP--PAKNTSPGPVSSP---GRASG 122

Query: 688 VARDQPA------LAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGA 741
             R  P       ++ EE+  RG   E      LS  A       +   GP PG      
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAM 176

Query: 742 APEPLGASVQ----RDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQG 797
           A     A  +    R +   RP PP + P      AS  +   P PA   + SA    Q 
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 798 PAEPIPPGVASGGLRPDALGPTT--AHHGPRHP--PK-------------PPRSKATERP 840
           PA       A+    P   GP+       P HP  PK             PPR  A    
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 841 GQEPEGPGAT--PAGERDDQSPDSVPERPRPADRRLCLPCVDASPL----PGRTACPSLQ 894
           G     P AT  P+     Q+P ++P  P  +     L C  A+PL    P  +A PSLQ
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSS----LTCQLATPLPLAPPSPSAPPSLQ 352



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 56/194 (28%), Positives = 77/194 (39%), Gaps = 33/194 (17%)

Query: 723 SPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV 782
           SP    P  P+  P PQ  AP  L   + +      P PP QAP + P    ++ P SP 
Sbjct: 410 SPPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQAPFSPP----ASPPVSPS 463

Query: 783 PAPPTKA----SALPVEQGPAEPIPPGVASGGLRPDALGPTTAH---HGPRHPPKPPRSK 835
             PP++A    +A P++  P+ P  P ++     P    P  A       + PP+ P + 
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 836 AT-----------ERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPL 884
           AT             PGQ P  P A+        SP + P  P  A   L  P +   P 
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSASL-----PMSPLATP--PPQAPPVLAAPLLQVPPS 576

Query: 885 PGRTACPSLQEATR 898
           P   A P+LQ   R
Sbjct: 577 P--PASPTLQAPRR 588



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 170/727 (23%), Positives = 231/727 (31%), Gaps = 120/727 (16%)

Query: 183 SSCRVCRSLSAVGRRVLSIESFG-ALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLP 241
           ++ RV  +  AVGR+ L+  + G     + ES+ R       AGP R  G  S +P   P
Sbjct: 42  AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR-------AGPTRSAGTSSRNPASRP 94

Query: 242 TPEG------PESETSRGPRASPTKALLSTPVRNGESHSREGLAGLVLDAERTLGE-LDR 294
              G      P   TS GP +SP +A  S   R G      G  GL + AE T+      
Sbjct: 95  PASGRGERAPPAKNTSPGPVSSPGRA--SGTTRPGPL----GQKGLRISAEETVARGKAT 148

Query: 295 DALRRSRL----RKVQTFPRLLSDSPE-------------------ATLCLPLTRG--KS 329
           +A +RS L    R+  + P   + SP                    +    P T G  KS
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208

Query: 330 QLPISELFSPDPRKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGV 389
               SE  + +P  A   R +     Q      L     P     R   + R T R P  
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268

Query: 390 PGSPGQPETSHPSQGPAEAPADPRDASGEAQTPRDDERI--PEGARQLESAAAEQWVSL- 446
           P  P +P+     + P   P  PR  +  A  P     +  P  +  L+S A     +  
Sbjct: 269 PSQP-KPKGLQALRPPQVTP--PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325

Query: 447 --QDLLSQLGRPFREYELWALCLACLRALQTRPEHPAYLCLDSVLVAEDGAVLFQPPPAN 504
               L  QL  P     L     +   +LQT P  PA             A      P  
Sbjct: 326 HSSSLTCQLATPL---PLAPPSPSAPPSLQTLPSPPA--------TPPSQATTSLGSPTL 374

Query: 505 GSYDSFFLAPELAEERLVTEKASVYCVAAVLWTAAKFSVPRNHKLA--------LPRRLK 556
            +  SF  +P L+   L T         A+    A  S P +  L+         P  L 
Sbjct: 375 QATHSFLPSPPLSP--LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432

Query: 557 TLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRASICQVYQEEETISLQN 616
             LL       P  P  A         +        +    L A   QV           
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA---SP 489

Query: 617 AFSVVELKPSVAPAP---------EPSPGFLPVNSDTGLVAVPGP---VPGQHPCGEEAT 664
             S     P  AP P         +P P   P  +   L A+P P    PGQ P    A+
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549

Query: 665 QLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERG---GQREGEGEEKLSLEAHA 721
              +   +      P++ A    V    PA    ++  R    G        +L+L    
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609

Query: 722 GSPS--LKTPDGPVPGPGPQG------AAPEPLGASVQRDSAQGRPCPPPQA------PA 767
           G P    ++P   + GP   G      + PE L              PPP A      PA
Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 669

Query: 768 NQPEG-----ASSAAPGSPVPAPPTKA-------SALPVEQGPAEPIP-PGVASGGLRPD 814
               G     A   APG+P+P PP            +   +GP    P PG    G  P 
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729

Query: 815 ALGPTTA 821
             G   A
Sbjct: 730 TSGGKAA 736



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 48/176 (27%), Positives = 60/176 (34%), Gaps = 14/176 (7%)

Query: 724 PSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVP 783
           PSL+T   P P   P   A   LG+   + +    P PP    A  P  A  A    P+ 
Sbjct: 349 PSLQTL--PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406

Query: 784 APPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQE 843
           APP+  +        + P+ P        P+AL           PP PP       P   
Sbjct: 407 APPSPPA--------SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458

Query: 844 PEGPGATPAGERDDQ---SPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEA 896
           P  P ATP  +        P  VP  P PA   +          P   A P LQ A
Sbjct: 459 PVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQLA 513



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 74/314 (23%), Positives = 106/314 (33%), Gaps = 51/314 (16%)

Query: 625 PSVAPAPEPSPGFLPVNSDTG-LVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
           PS  P P        V+S +      P P   + P      Q PA+ +  ++       A
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 684 QNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSL-KTPDGPVPGPGPQGA- 741
           ++   AR  P      S+ +    +     +++      +P+L      P+  P P  A 
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL 313

Query: 742 ---APEPLGASVQRDS-----------AQGRPCPPPQ-----APANQPEGASSAAPGSP- 781
              AP  L A+    S           A   P  PP      +P   P   ++ + GSP 
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373

Query: 782 -------VPAPPTKASALPVEQGP---------AEPIPPGVASGGLRPDALGP-----TT 820
                  +P+PP    A P  Q P         A P PP  AS  L P A          
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP--ASPPLSPLATPSPQAPNAL 431

Query: 821 AHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVD 880
           A H  + P  PP S   + P   P  P  +P+     Q+P S+   P         P   
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-----PSPP 486

Query: 881 ASPLPGRTACPSLQ 894
           ASP    +A P  Q
Sbjct: 487 ASPPMSPSATPPPQ 500



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 46/172 (26%), Positives = 60/172 (34%), Gaps = 15/172 (8%)

Query: 722 GSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSP 781
           GSP+L+     +P P     A  P  A            PP QAP + P     +   +P
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQAP------PALALPPLQAPPSPPASPPLSPLATP 423

Query: 782 VPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGP--RHPPK---PPRSKA 836
            P  P  A A+ + Q P  P P         P A  P +    P  + PP    PP    
Sbjct: 424 SPQAP-NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482

Query: 837 TERPGQEPEGPGATPAGERDD---QSPDSVPERPRPADRRLCLPCVDASPLP 885
              P   P  P ATP  +        P  + + P  A   L  P + A P P
Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534



 Score = 35.0 bits (79), Expect = 0.64
 Identities = 48/173 (27%), Positives = 58/173 (33%), Gaps = 20/173 (11%)

Query: 717 LEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGR--PCPPPQAPANQPEGAS 774
           L   AG     T     P  GP  +A         R  A GR    PP +  +  P  + 
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117

Query: 775 SAAPGSPVPAPPTK-----ASALPVEQGPAEPIPPGVA-SGGLRPDALGPTTAHHGPRHP 828
             A G+  P P  +     ++   V +G A   P   A S G R D  GPT    G   P
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP---GTPSP 174

Query: 829 PKPPRSKAT--------ERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRR 873
               RS+A           P   P  P   P       S  S  E P PA RR
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-PSPAARR 226



 Score = 31.6 bits (70), Expect = 7.1
 Identities = 46/173 (26%), Positives = 51/173 (29%), Gaps = 48/173 (27%)

Query: 738 PQGAAPEPLGASVQRDSAQGRPCPP----------------------------------- 762
           P   AP   G    R     RP PP                                   
Sbjct: 17  PAARAP---GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 763 -PQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPI-PPGVASGGLRPDALGPTT 820
            P+A   +  G SS  P S  PA      A P +     P+  PG ASG  RP  LG   
Sbjct: 74  APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 821 AHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRR 873
                       R KATE P +     GA     RD   P   P  P PA  R
Sbjct: 134 LRISAEE--TVARGKATEAPKRSALSAGA----RRDTSGP--TPGTPSPAMAR 178


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 81/305 (26%), Positives = 105/305 (34%), Gaps = 44/305 (14%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P ++P   P P   P  +   L A P P P   P    AT  P A  + A H      + 
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSP 403

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA----GSPSLKTPDGPVPGPGPQG 740
             S     P  +   S           +   SL A       SP    P  P   P PQ 
Sbjct: 404 PPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ- 461

Query: 741 AAPEPLGA--------------SVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPP 786
            AP PL A              ++     Q  P PP   P   P   S++ P SP+  PP
Sbjct: 462 -APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 787 TKAS---ALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPR--------HPPKPPRSK 835
            +A    A P+ Q P  P          RP   GP T+  GPR         PP P RS 
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580

Query: 836 ATERPGQEPEGPGATPAGERDD-QSPDSVPE------RPRPADRRLCLPCV----DASPL 884
           ++   G +  G  ++     ++ +  DS PE       P  A+   C P       A PL
Sbjct: 581 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 640

Query: 885 PGRTA 889
             R A
Sbjct: 641 AFRGA 645



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 56/194 (28%), Positives = 77/194 (39%), Gaps = 33/194 (17%)

Query: 723 SPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV 782
           SP    P  P+  P PQ  AP  L   + +      P PP QAP + P    ++ P SP 
Sbjct: 371 SPPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQAPFSPP----ASPPVSPS 424

Query: 783 PAPPTKA----SALPVEQGPAEPIPPGVASGGLRPDALGPTTAH---HGPRHPPKPPRSK 835
             PP++A    +A P++  P+ P  P ++     P    P  A       + PP+ P + 
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484

Query: 836 AT-----------ERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPL 884
           AT             PGQ P  P A+        SP + P  P  A   L  P +   P 
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSASL-----PMSPLATP--PPQAPPVLAAPLLQVPPS 537

Query: 885 PGRTACPSLQEATR 898
           P   A P+LQ   R
Sbjct: 538 P--PASPTLQAPRR 549



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 60/217 (27%), Positives = 73/217 (33%), Gaps = 25/217 (11%)

Query: 695 LAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQ--- 751
           ++ EE+  RG   E      LS  A       +   GP PG      A     A  +   
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAMARRSRAAGTEVGL 180

Query: 752 -RDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGG 810
            R +   RP PP + P      AS  +   P PA   + SA    Q PA       A+  
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240

Query: 811 LRPDALGPTT--AHHGPRHP--PKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPER 866
             P   GP+       P HP  PKP   +A   P   P    A PA      SP + P  
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300

Query: 867 PRPADRRLCLPCVDASP----LPGRTACPSLQEATRL 899
             P       P   A P    LP   A P  Q  T L
Sbjct: 301 SAP-------PSPSAPPSLQTLPSPPATPPSQATTSL 330



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 87/336 (25%), Positives = 113/336 (33%), Gaps = 74/336 (22%)

Query: 615 QNAFSVVELKPSVAPAP-EPSPGFLPVNSDTGL-VAVPGPVPGQHPCGEEATQLPAAFTS 672
           ++A S    + +  P P  PSP     +   G  V +P P P   P     T+ P    S
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--RPPTEGPRKSVS 201

Query: 673 EATHFKPIVLAQNASVARDQPALAQEESEERGGQREGE-----GEEKLSLEAHAGSPSLK 727
            A+           S     PA  +  S   G QR            LS  A +G  +  
Sbjct: 202 SASEH---------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252

Query: 728 TPDGPV--PGPGPQG---------------AAPE--PLGAS---VQRDSAQGRPCPPPQ- 764
           TP  P     P P+G               AAP   PL +S       SA   P  PP  
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312

Query: 765 ----APANQPEGASSAAPGSP--------VPAPPTKASALPVEQGP---------AEPIP 803
               +P   P   ++ + GSP        +P+PP    A P  Q P         A P P
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372

Query: 804 PGVASGGLRPDALGP-----TTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           P  AS  L P A          A H  + P  PP S   + P   P  P  +P+     Q
Sbjct: 373 P--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430

Query: 859 SPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQ 894
           +P S+   P         P   ASP    +A P  Q
Sbjct: 431 APPSLAAPPLQVP-----PSPPASPPMSPSATPPPQ 461



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 48/176 (27%), Positives = 60/176 (34%), Gaps = 14/176 (7%)

Query: 724 PSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVP 783
           PSL+T   P P   P   A   LG+   + +    P PP    A  P  A  A    P+ 
Sbjct: 310 PSLQTL--PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367

Query: 784 APPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQE 843
           APP+  +        + P+ P        P+AL           PP PP       P   
Sbjct: 368 APPSPPA--------SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419

Query: 844 PEGPGATPAGERDDQ---SPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEA 896
           P  P ATP  +        P  VP  P PA   +          P   A P LQ A
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQLA 474



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 46/172 (26%), Positives = 60/172 (34%), Gaps = 15/172 (8%)

Query: 722 GSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSP 781
           GSP+L+     +P P     A  P  A            PP QAP + P     +   +P
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAP------PALALPPLQAPPSPPASPPLSPLATP 384

Query: 782 VPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGP--RHPPK---PPRSKA 836
            P  P  A A+ + Q P  P P         P A  P +    P  + PP    PP    
Sbjct: 385 SPQAP-NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 837 TERPGQEPEGPGATPAGERDD---QSPDSVPERPRPADRRLCLPCVDASPLP 885
              P   P  P ATP  +        P  + + P  A   L  P + A P P
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 160/705 (22%), Positives = 218/705 (30%), Gaps = 115/705 (16%)

Query: 183 SSCRVCRSLSAVGRRVLSIESFG-ALQDVSESSWR------ERPAPGNAGPRRPPGDPST 235
           ++ RV  +  AVGR+ L+  + G     + ES+ R       RP     G R PP   +T
Sbjct: 42  AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAK-NT 100

Query: 236 DPEVLPTPEGPESETSRGPRASP-TKALLSTPVRNGESHSREGLAGLVLDAER-----TL 289
            P  + +P      T  GP      +      V  G++      + L   A R     T 
Sbjct: 101 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 160

Query: 290 GELDRDALRRSRLRKVQT-FPRLLSDSPEATLCLPLTRG--KSQLPISELFSPDPRKAFL 346
           G       RRSR    +   PR    +P A    P T G  KS    SE  + +P  A  
Sbjct: 161 GTPSPAMARRSRAAGTEVGLPR---PAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAAR 216

Query: 347 DRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPG-------QPETS 399
            R +     Q      L     P     R   + R T R P  P  P        +P   
Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 276

Query: 400 HPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAAEQWVSLQDLLSQLGRPFRE 459
            P +  A     P  +S  A         P     L++  +          + LG P  +
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336

Query: 460 YELWALCLACLRALQTRP-EHPAYLCLDSVLVAEDGAVLFQPPPANGSYDSFFLAPELAE 518
                L    L  L T P + P  L L  +          Q PP+  +      +P L+ 
Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPL----------QAPPSPPA------SPPLSP 380

Query: 519 ERLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIK 578
             L T         AV    A FS P +  +  P             S P  PSA    +
Sbjct: 381 --LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--------SPPVSPSATPPSQ 430

Query: 579 VCGSYLLQRGMDSRKILAHLRASICQVYQEEETISLQNAFSVVELKPSVAPAP------- 631
              S               L A   QV             S     P  AP P       
Sbjct: 431 APPS---------------LAAPPLQVPPSPPA---SPPMSPSATPPPQAPPPLAAPPLQ 472

Query: 632 --EPSPGFLPVNSDTGLVAVPGP---VPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNA 686
             +P P   P  +   L A+P P    PGQ P    A+   +   +      P++ A   
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532

Query: 687 SVARDQPALAQEESEERG---GQREGEGEEKLSLEAHAGSPS--LKTPDGPVPGPGPQG- 740
            V    PA    ++  R    G        +L+L    G P    ++P   + GP   G 
Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 592

Query: 741 -----AAPEPLGASVQRDSAQGRPCPPPQA------PANQPEG-----ASSAAPGSPVPA 784
                + PE L              PPP A      PA    G     A   APG+P+P 
Sbjct: 593 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 652

Query: 785 PPTKA-------SALPVEQGPAEPIP-PGVASGGLRPDALGPTTA 821
           PP            +   +GP    P PG    G  P   G   A
Sbjct: 653 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 697



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 52/165 (31%), Positives = 58/165 (35%), Gaps = 26/165 (15%)

Query: 721 AGSPSLKTP---DGPVPGPGPQGAAPEPLGAS--------VQRDSAQGRPCPPPQAPANQ 769
           A +P L TP     P P P    AA   LGA+         +R    G    P  AP   
Sbjct: 19  ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78

Query: 770 PEGASSA-APGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHP 828
           P   S   A G    APP K ++      P     PG ASG  RP  LG           
Sbjct: 79  PTRTSRPPASGRGERAPPAKNTS------PGPVSSPGRASGTTRPGPLGQKGLRISAEE- 131

Query: 829 PKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRR 873
               R KATE P +     GA     RD   P   P  P PA  R
Sbjct: 132 -TVARGKATEAPKRSALSAGA----RRDTSGP--TPGTPSPAMAR 169



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 6/102 (5%)

Query: 751 QRDSAQ-GRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPV--EQGPAEPIPPGVA 807
           +RD A+ G     P A A  P   +   PGSP P PP   +AL V    G     P    
Sbjct: 4   KRDKAKAGAAARTPAARA--PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61

Query: 808 SGGLRPDALGPTTAHHGPRHPPKPPRSKATER-PGQEPEGPG 848
           +GG+    +  +    GP    +PP S   ER P  +   PG
Sbjct: 62  AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPG 103


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 85/333 (25%), Positives = 118/333 (35%), Gaps = 71/333 (21%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLP---AAFTSEATHFKP--- 679
           +V PAP+  P           V+ P P+  Q P  ++  Q P   AA   +AT  +P   
Sbjct: 620 TVQPAPQAPPA----------VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPG 669

Query: 680 -------IVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEA-HAGSPSLKTPDG 731
                  IVL Q  S      A+  ++S +    +E   ++ LS E  H   P+      
Sbjct: 670 LASSPEKIVLGQPPSAT--PTAILTQDSLQMFLPQE-RSQQPLSAEGPHLSVPASVIVSA 726

Query: 732 PVPGPGPQGAAPEPLGASV--QRDSAQGRPCPPPQAPANQP---EGASSAA--------- 777
           P P   P  A P   GA +  Q   +Q  P P PQ PA  P    G SS+          
Sbjct: 727 PPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG 786

Query: 778 ---------PGSPVPAPPTKASAL--PVEQGPAEPIPPGVASG------------GLRPD 814
                    P  P   PP++  ++  P  + P  P PP  A              G+ P 
Sbjct: 787 DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP 846

Query: 815 ALGPTTAHHGPRHPPKPPRSKATERPGQEPE--GPGATPAGERDDQSPDSVPERPRPADR 872
           A  P     GP  PP  P+S+  E P        P +T +         S    P P+D 
Sbjct: 847 ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906

Query: 873 RLCLPCVDASPLPGRTACPSLQEATRLIQEEFA 905
           +L  P     P  G    P+      L+ E  A
Sbjct: 907 QLQFP-----PSQGPHKSPTPPPTLHLVPEPAA 934



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 177/752 (23%), Positives = 258/752 (34%), Gaps = 149/752 (19%)

Query: 219  PAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTKALLSTPVRNGESHSREGL 278
            PAP   GP +PP  P + P     PEGP       P +S + A+ S+             
Sbjct: 850  PAPTAPGPPQPPLRPQSQP-----PEGPLPPAPHLPPSSTSSAVASS------------- 891

Query: 279  AGLVLDAERTLGELDRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFS 338
                     T   L        +L+   +     S +P  TL L        +P      
Sbjct: 892  -------SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL--------VPEPAAPP 936

Query: 339  PDPRKAFLDRKNGLSSFQA--QPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQP 396
            P P + F   +   + F A  QPK  L    E  HQ   VP +G       G  G+P  P
Sbjct: 937  PPPPRTF---QMVTTPFPALPQPKALL----ERFHQ---VP-SGIILQNKAG--GAPAAP 983

Query: 397  ETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAAEQWVSLQDLLSQLGRP 456
            +TS  S GP  +PA     SG+A  P      P  A      AA     L  LL    + 
Sbjct: 984  QTS-TSLGPLTSPAASVLVSGQA--PSGTPTAPSHAPAPAPMAA---TGLPPLLPAENKA 1037

Query: 457  FREYELWALCLACLRALQTRPEHPAYLCLDSVLVAEDGAVLFQPPPANGSYDSFFLA--- 513
            F    L  L +A  +A  + P  P+ L  +S L       L +PP    S ++ FL    
Sbjct: 1038 FAS-NLPTLNVA--KAASSGPGKPSGLQYESKLSG-----LKKPPTLQPSKEACFLEHLH 1089

Query: 514  --------PELAEERLVTEKASVYCVAAVLWTAAKFSVPRNHKL---------------- 549
                    P+        E A    +   ++  A  S    HK+                
Sbjct: 1090 KHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQ 1149

Query: 550  ALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRASICQVYQEE 609
            A+  + + LLL+ +RR +P    +AE + +   ++ +      K    L   + +   +E
Sbjct: 1150 AMLNKYRLLLLEESRRVSP----SAEMVMIDRMFIQEE-----KTTLALDKQLAKEKPDE 1200

Query: 610  ETISLQN------AFSVVELKPSVAPAPEPSPGFL---PVNSDTGLVAVPGPVPGQHPC- 659
               S ++      A S     P   P    +PG     P +  T LV   G   G     
Sbjct: 1201 YVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVT 1260

Query: 660  -GEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQR-EGEGEEKLSL 717
                ++ L ++ +S +              +R++P +   E+  R G + + + E  LS 
Sbjct: 1261 WARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSK 1320

Query: 718  EAH--AGSPSLKTPDGP----VPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPE 771
              H  A  P  + P  P    V  P P+   P P    +          PPP AP  +P 
Sbjct: 1321 VVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDH----PPPAAPERKPL 1376

Query: 772  GASSAAPGSPV----------PAPPTKASALPVEQGPAEPIPPGV---ASGGLRPDALGP 818
            G +   P  P+          P  P    A     G   P+P  V    SG +R  A   
Sbjct: 1377 GTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVE 1436

Query: 819  TTAHH----GPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPD---SVPERPRPAD 871
               +     GP  PP+P  S A      + E PG  PA  R  +SPD   +      P D
Sbjct: 1437 DELYQRMLKGP--PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQD 1494

Query: 872  RRLCL-------PCVDASPLPGRTACPSLQEA 896
              L           ++    PGRT  PS   A
Sbjct: 1495 DTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA 1526



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 75/286 (26%), Positives = 94/286 (32%), Gaps = 71/286 (24%)

Query: 651 GPVPGQHPCGEEATQLPAA---FTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQR 707
           GPV   H     A  L AA       A    P+ LA  +   + QPA A        G  
Sbjct: 527 GPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA--------GPA 578

Query: 708 EGEGEEKLSLEAHAGSPSLKTPDGPV-------------------PGPGPQGAAPEPLGA 748
                + ++L   A +  L TPDG V                   P P    A   PL  
Sbjct: 579 ATTVLQGVTLPPSAVA-MLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL 637

Query: 749 SVQRDSAQGRP-------CPPPQAPANQPEGASSAAP-----GSPVPAPPTKASA----- 791
            +Q+  AQ  P         PPQA   QP    +++P     G P  A PT         
Sbjct: 638 GLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQ 697

Query: 792 --LPVE--------QGPAEPIPPGVASGGLRP--DALGPTTAHHGPRHPPKPPRSKATER 839
             LP E        +GP   +P  V      P  D    T    G    P+ P S+A+  
Sbjct: 698 MFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS-- 755

Query: 840 PGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLP 885
           P   P+ P A P        P S P  P  A      P  D+  LP
Sbjct: 756 PAPAPQIPAAAPL---KGPGPSSSPSLPHQA------PLGDSPHLP 792


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 56/191 (29%), Positives = 78/191 (40%), Gaps = 32/191 (16%)

Query: 693 PALAQEESEERGGQREGE---GEEKLSLEA--HAGSPSLKTPDGPVPGPGPQGAAPEPLG 747
           PA  +  S+   GQ + +   G  +LS+    +A  PS  T    V  P P  A P+P  
Sbjct: 510 PAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAP--APPKPGN 567

Query: 748 ASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVE---QGPAEPIPP 804
                        PPP  P  Q    +S  P S  P PPT++ + P +   Q P +P  P
Sbjct: 568 -------------PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAP 614

Query: 805 GVASGGLR-PDALGPTTAHHGPRHPPKPPRSKA-----TERPGQEPEGPGATPAGERDDQ 858
              S   R   +L P  A   P HPP  P ++A     T+   Q P  P A P+    +Q
Sbjct: 615 SQLSAPRRYSSSLSPIQA---PNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQ 671

Query: 859 SPDSVPERPRP 869
              + P+ P P
Sbjct: 672 PSHTPPQTPTP 682



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 46/173 (26%), Positives = 55/173 (31%), Gaps = 28/173 (16%)

Query: 726 LKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRP---CPPPQAPANQPEGASSAAPGS-- 780
           +K    P P      A P P   + Q  S Q +P       Q    QP  A+  +P +  
Sbjct: 493 VKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 552

Query: 781 -----PVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHP---PKPP 832
                P PAPP           P  P PPG   GG              P+ P   P PP
Sbjct: 553 RAVKKPAPAPPK----------PGNP-PPG-HPGGQSSSGTSQHPPSLSPKPPTRSPSPP 600

Query: 833 RSKATERPGQEPEGPGATPAGER--DDQSPDSVPERPRPADRRLCLPCVDASP 883
                + PGQ P  P    A  R     SP   P  P P       P +   P
Sbjct: 601 TQHTGQPPGQ-PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKP 652


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 62/240 (25%), Positives = 83/240 (34%), Gaps = 24/240 (10%)

Query: 629 PAPEPSPGFLPVNSDTGLVAVPGPVPGQ-----HPCG--EEATQLPAAFTSEATHFKPIV 681
           P  +PS    P+    G V  P   PG       P G  +   Q   +    +    P  
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390

Query: 682 LAQNASVAR---DQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGP-- 736
           LAQ   V +    QP  A+  +++ G  +    +  L   A A  P+      P PG   
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450

Query: 737 ----GPQGAAPEPLGASVQRDSAQGRPCPPPQAPA------NQPEGAS--SAAPGSPVPA 784
               GP   + +  G +       G   PPPQ P        QP  A   S  PGS  P 
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510

Query: 785 PPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEP 844
           P     A P  Q P    PP    G  +P A  P+ A    +   KP     + +P Q P
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 49/198 (24%), Positives = 74/198 (37%), Gaps = 24/198 (12%)

Query: 687 SVARDQPALAQEESEERGGQREGEGEE------KLSLEAHAGSPSLKTPDGPVPGPGPQG 740
           S++  QP   + +    G   +G  +       KL L+  A  P  K  D  V G   + 
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQAD-IVRGESVKP 296

Query: 741 AAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAE 800
           + P P    +Q+ +       P + PA QP G   + PG   P         P+ Q P  
Sbjct: 297 SLPSPSKPPIQQPT-------PGKPPAQQP-GHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPP-RSKATERPGQEPEGPGATPAGERDDQS 859
             PP    G  +P A         P  P KPP +   +E+P  E  GP A        ++
Sbjct: 349 VKPPVQPPGTTKPPA--------QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400

Query: 860 PDSVPERPRPADRRLCLP 877
           P   P   +P  +++  P
Sbjct: 401 PAQQPGPAKPPTQQVGTP 418



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 56/234 (23%), Positives = 81/234 (34%), Gaps = 22/234 (9%)

Query: 624 KPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
           KPS   + +P P  L      G      P P + P  +  T  P A        +P + +
Sbjct: 380 KPS---SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ-------QPGLQS 429

Query: 684 QNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPS-LKTPDGPVPG-PGPQGA 741
              +    +  + Q    +   Q+ G G+           PS L  P  P P  PGP   
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489

Query: 742 APEPLGASVQRDSAQGRPCPPPQAPA------NQPEGAS--SAAPGSPVPAPPTKASALP 793
            P+  G++       G   PPPQ P        QP      S  PGS  P+    + A P
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549

Query: 794 VEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKP--PRSKATERPGQEPE 845
             Q   +P+    +   L+P  + P+      +  PK   P    TE     PE
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE 603



 Score = 38.1 bits (87), Expect = 0.076
 Identities = 63/263 (23%), Positives = 90/263 (34%), Gaps = 38/263 (14%)

Query: 608 EEETISLQNAFSVVELKPS--VAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEAT- 664
           +EET   Q      + KP   + P  +  P   P+    G        PG+ P  ++ T 
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPP-KPIPKQQG--------PGRDPLQQDGTP 236

Query: 665 -----QLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEA 719
                Q P    S+       +     +   D   L  +    R   ++ +     S++ 
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296

Query: 720 HAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPG 779
              SPS      P PG  P   A +P        S  G   PP Q        A      
Sbjct: 297 SLPSPSKPPIQQPTPGKPP---AQQP----GHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349

Query: 780 SPVPAPP--TKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKAT 837
            P   PP  TK  A P+  GPA+  PP   +G  +P +  P     GP+   +PP    T
Sbjct: 350 KPPVQPPGTTKPPAQPL--GPAK--PPAQQTGSEKPSSEQP-----GPKALAQPPGVGKT 400

Query: 838 ERPGQEPEGPGATPAGERDDQSP 860
             P Q+P GP   P  +     P
Sbjct: 401 --PAQQP-GPAKPPTQQVGTPKP 420



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 67/283 (23%), Positives = 91/283 (32%), Gaps = 56/283 (19%)

Query: 571  PSAAEAIKVCGSYLLQRGMDSRKILAHLRAS--------ICQVYQEEETISLQNAFSVVE 622
            P   E +    S  + R     KI++H   S        +  V ++EE    Q   S   
Sbjct: 807  PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP-- 864

Query: 623  LKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVL 682
             KP   P P+ SP              PGP P          Q P     E +    + L
Sbjct: 865  -KPDAKPMPKGSP------------TPPGPRPTAGQTVPTPQQSPKP--QEQSRRFSLNL 909

Query: 683  AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                   + QP   QE      G+  G G    S  ++  S + +        PGP    
Sbjct: 910  GSITDAPKSQPTTPQETVT---GKLFGFGASIFSQASNLISTAGQ--------PGPH--- 955

Query: 743  PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPI 802
                       S  G   P  QAPA      S   P S   APP  A ++PV++    P 
Sbjct: 956  -----------SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP- 1003

Query: 803  PPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPE 845
                A+  L P A    T         KPP  K ++    EP+
Sbjct: 1004 ----AAEKLEPKAEQAPTVKR-TETEKKPPPIKDSKSLTAEPQ 1041



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 44/159 (27%), Positives = 60/159 (37%), Gaps = 32/159 (20%)

Query: 711  GEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQP 770
            G+EK + +  +GSPS+ +    +P      A P P   S   D +   P PPP  P   P
Sbjct: 2368 GQEKPASQLPSGSPSVSS----LP------AKPRPFFRSSSLDISAQPPPPPPPPPPPPP 2417

Query: 771  EGASSAAPGSPVPAPPTKASALPVEQ-GPAEPIPPGV----------ASGGLRPDALGPT 819
                   P  P P  P K + LP ++   A P+               +  LR + L P 
Sbjct: 2418 PPPPPPPPPLPPPTSP-KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL-PV 2475

Query: 820  TAHHGPRHPPKPPRSKA-------TERPGQEPEGPGATP 851
            T       PP PP+  +       T RP  EP  P   P
Sbjct: 2476 TRICTTAPPPVPPKPSSIPSGLVFTHRP--EPSKPPIAP 2512



 Score = 32.7 bits (73), Expect = 3.2
 Identities = 43/183 (23%), Positives = 68/183 (37%), Gaps = 33/183 (18%)

Query: 239  VLPTPEGPESETSRGPRASPTKALLS--TPVRNGESHSREGLAGLVLDAERTLGELDRDA 296
            V+P PEGP ++T        T  L+S   PV+  +  +  G+   VL+A R   EL+ + 
Sbjct: 2277 VVPKPEGPVADT------VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAER 2330

Query: 297  LRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPD------PRKAFLDRKN 350
             + S    V   P      P + + LP+   K QL  +   S +      P         
Sbjct: 2331 TKSSLSETVFDHP------PSSVIALPM---KEQLSTTYFTSGETFGQEKPASQLPSGSP 2381

Query: 351  GLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPA 410
             +SS  A+P+        P  +   +  + +     P  P  P  P    P   P   P 
Sbjct: 2382 SVSSLPAKPR--------PFFRSSSLDISAQPPP--PPPPPPPPPPPPPPPPPPPLPPPT 2431

Query: 411  DPR 413
             P+
Sbjct: 2432 SPK 2434



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 7/123 (5%)

Query: 143 EPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQ---LTSSCRVCRSLSAVGRRVL 199
           +P++ +    L+S   A    D P    + +  EEK      T S +  +S    G +V 
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPS-SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS 814

Query: 200 SIESFGALQDVSESSWRERPAPGNAGPRRPPGDP---STDPEVLPTPEGPESETSRGPRA 256
             +S    +  S+S     P P +    +   DP     +P+   T   P+ +    P+ 
Sbjct: 815 PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874

Query: 257 SPT 259
           SPT
Sbjct: 875 SPT 877


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 62/240 (25%), Positives = 83/240 (34%), Gaps = 24/240 (10%)

Query: 629 PAPEPSPGFLPVNSDTGLVAVPGPVPGQ-----HPCG--EEATQLPAAFTSEATHFKPIV 681
           P  +PS    P+    G V  P   PG       P G  +   Q   +    +    P  
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390

Query: 682 LAQNASVAR---DQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGP-- 736
           LAQ   V +    QP  A+  +++ G  +    +  L   A A  P+      P PG   
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450

Query: 737 ----GPQGAAPEPLGASVQRDSAQGRPCPPPQAPA------NQPEGAS--SAAPGSPVPA 784
               GP   + +  G +       G   PPPQ P        QP  A   S  PGS  P 
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510

Query: 785 PPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEP 844
           P     A P  Q P    PP    G  +P A  P+ A    +   KP     + +P Q P
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 49/198 (24%), Positives = 74/198 (37%), Gaps = 24/198 (12%)

Query: 687 SVARDQPALAQEESEERGGQREGEGEE------KLSLEAHAGSPSLKTPDGPVPGPGPQG 740
           S++  QP   + +    G   +G  +       KL L+  A  P  K  D  V G   + 
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQAD-IVRGESVKP 296

Query: 741 AAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAE 800
           + P P    +Q+ +       P + PA QP G   + PG   P         P+ Q P  
Sbjct: 297 SLPSPSKPPIQQPT-------PGKPPAQQP-GHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPP-RSKATERPGQEPEGPGATPAGERDDQS 859
             PP    G  +P A         P  P KPP +   +E+P  E  GP A        ++
Sbjct: 349 VKPPVQPPGTTKPPA--------QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400

Query: 860 PDSVPERPRPADRRLCLP 877
           P   P   +P  +++  P
Sbjct: 401 PAQQPGPAKPPTQQVGTP 418



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 56/234 (23%), Positives = 81/234 (34%), Gaps = 22/234 (9%)

Query: 624 KPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
           KPS   + +P P  L      G      P P + P  +  T  P A        +P + +
Sbjct: 380 KPS---SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ-------QPGLQS 429

Query: 684 QNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPS-LKTPDGPVPG-PGPQGA 741
              +    +  + Q    +   Q+ G G+           PS L  P  P P  PGP   
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489

Query: 742 APEPLGASVQRDSAQGRPCPPPQAPA------NQPEGAS--SAAPGSPVPAPPTKASALP 793
            P+  G++       G   PPPQ P        QP      S  PGS  P+    + A P
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549

Query: 794 VEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKP--PRSKATERPGQEPE 845
             Q   +P+    +   L+P  + P+      +  PK   P    TE     PE
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE 603



 Score = 38.1 bits (87), Expect = 0.076
 Identities = 63/263 (23%), Positives = 90/263 (34%), Gaps = 38/263 (14%)

Query: 608 EEETISLQNAFSVVELKPS--VAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEAT- 664
           +EET   Q      + KP   + P  +  P   P+    G        PG+ P  ++ T 
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPP-KPIPKQQG--------PGRDPLQQDGTP 236

Query: 665 -----QLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEA 719
                Q P    S+       +     +   D   L  +    R   ++ +     S++ 
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296

Query: 720 HAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPG 779
              SPS      P PG  P   A +P        S  G   PP Q        A      
Sbjct: 297 SLPSPSKPPIQQPTPGKPP---AQQP----GHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349

Query: 780 SPVPAPP--TKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKAT 837
            P   PP  TK  A P+  GPA+  PP   +G  +P +  P     GP+   +PP    T
Sbjct: 350 KPPVQPPGTTKPPAQPL--GPAK--PPAQQTGSEKPSSEQP-----GPKALAQPPGVGKT 400

Query: 838 ERPGQEPEGPGATPAGERDDQSP 860
             P Q+P GP   P  +     P
Sbjct: 401 --PAQQP-GPAKPPTQQVGTPKP 420



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 67/283 (23%), Positives = 91/283 (32%), Gaps = 56/283 (19%)

Query: 571  PSAAEAIKVCGSYLLQRGMDSRKILAHLRAS--------ICQVYQEEETISLQNAFSVVE 622
            P   E +    S  + R     KI++H   S        +  V ++EE    Q   S   
Sbjct: 807  PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP-- 864

Query: 623  LKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVL 682
             KP   P P+ SP              PGP P          Q P     E +    + L
Sbjct: 865  -KPDAKPMPKGSP------------TPPGPRPTAGQTVPTPQQSPKP--QEQSRRFSLNL 909

Query: 683  AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                   + QP   QE      G+  G G    S  ++  S + +        PGP    
Sbjct: 910  GSITDAPKSQPTTPQETVT---GKLFGFGASIFSQASNLISTAGQ--------PGPH--- 955

Query: 743  PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPI 802
                       S  G   P  QAPA      S   P S   APP  A ++PV++    P 
Sbjct: 956  -----------SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP- 1003

Query: 803  PPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPE 845
                A+  L P A    T         KPP  K ++    EP+
Sbjct: 1004 ----AAEKLEPKAEQAPTVKR-TETEKKPPPIKDSKSLTAEPQ 1041



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 44/159 (27%), Positives = 60/159 (37%), Gaps = 32/159 (20%)

Query: 711  GEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQP 770
            G+EK + +  +GSPS+ +    +P      A P P   S   D +   P PPP  P   P
Sbjct: 2368 GQEKPASQLPSGSPSVSS----LP------AKPRPFFRSSSLDISAQPPPPPPPPPPPPP 2417

Query: 771  EGASSAAPGSPVPAPPTKASALPVEQ-GPAEPIPPGV----------ASGGLRPDALGPT 819
                   P  P P  P K + LP ++   A P+               +  LR + L P 
Sbjct: 2418 PPPPPPPPPLPPPTSP-KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL-PV 2475

Query: 820  TAHHGPRHPPKPPRSKA-------TERPGQEPEGPGATP 851
            T       PP PP+  +       T RP  EP  P   P
Sbjct: 2476 TRICTTAPPPVPPKPSSIPSGLVFTHRP--EPSKPPIAP 2512



 Score = 32.7 bits (73), Expect = 3.2
 Identities = 43/183 (23%), Positives = 68/183 (37%), Gaps = 33/183 (18%)

Query: 239  VLPTPEGPESETSRGPRASPTKALLS--TPVRNGESHSREGLAGLVLDAERTLGELDRDA 296
            V+P PEGP ++T        T  L+S   PV+  +  +  G+   VL+A R   EL+ + 
Sbjct: 2277 VVPKPEGPVADT------VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAER 2330

Query: 297  LRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPD------PRKAFLDRKN 350
             + S    V   P      P + + LP+   K QL  +   S +      P         
Sbjct: 2331 TKSSLSETVFDHP------PSSVIALPM---KEQLSTTYFTSGETFGQEKPASQLPSGSP 2381

Query: 351  GLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPA 410
             +SS  A+P+        P  +   +  + +     P  P  P  P    P   P   P 
Sbjct: 2382 SVSSLPAKPR--------PFFRSSSLDISAQPPP--PPPPPPPPPPPPPPPPPPPLPPPT 2431

Query: 411  DPR 413
             P+
Sbjct: 2432 SPK 2434



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 7/123 (5%)

Query: 143 EPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQ---LTSSCRVCRSLSAVGRRVL 199
           +P++ +    L+S   A    D P    + +  EEK      T S +  +S    G +V 
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPS-SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS 814

Query: 200 SIESFGALQDVSESSWRERPAPGNAGPRRPPGDP---STDPEVLPTPEGPESETSRGPRA 256
             +S    +  S+S     P P +    +   DP     +P+   T   P+ +    P+ 
Sbjct: 815 PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874

Query: 257 SPT 259
           SPT
Sbjct: 875 SPT 877


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 57/206 (27%), Positives = 74/206 (35%), Gaps = 46/206 (22%)

Query: 698 EESEERGGQREGEGEEKLSLEAHAGSPSLKTPDG------PVPGPG-PQGAAPEPLGASV 750
           E S E   Q E       SL   +G P  + P G      P P PG PQG  P P G + 
Sbjct: 17  ESSSEDVSQEE-------SLFLISGKPEGRRPQGGNQPQRPPPPPGKPQG--PPPQGGN- 66

Query: 751 QRDSAQGRPCPPPQAPANQPEGASSAA-----PGSP-------------VPAPPTKASAL 792
               +QG P PP +     P+G + +      PG P              P PP K    
Sbjct: 67  ---QSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERP 123

Query: 793 PVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPP--------RSKATERPGQEP 844
           P + G     PP       RP   G   +   P HP KP         +S++   P  +P
Sbjct: 124 PPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKP 183

Query: 845 EGPGATPAGERDDQSPDSVPERPRPA 870
           +GP      +     P   P+ P PA
Sbjct: 184 QGPPQQEGNKPQGPPPPGKPQGPPPA 209



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 63/238 (26%), Positives = 84/238 (35%), Gaps = 32/238 (13%)

Query: 640 VNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEE 699
           V+ +  L  + G   G+ P G    Q P     +     P     N S     P    E 
Sbjct: 23  VSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPP--QGGNQSQGPPPPPGKPEG 80

Query: 700 SEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQG-- 757
              +GG  + +G        H G P    P G   G   QG  P P     +R   QG  
Sbjct: 81  RPPQGGN-QSQGPPP-----HPGKPERPPPQG---GNQSQGTPPPP--GKPERPPPQGGN 129

Query: 758 ---RPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGP---AEPIPPGVASGGL 811
              RP PPP  P   P    + + G P    P K    P ++G    +   PPG   G  
Sbjct: 130 QSHRPPPPPGKPERPPPQGGNQSQGPP--PHPGKPEGPPPQEGNKSRSARSPPGKPQGP- 186

Query: 812 RPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRP 869
                 P    + P+ PP P + +     G  P+ P A PAG+   Q P   P+  RP
Sbjct: 187 ------PQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGK--PQGPPPPPQGGRP 236



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 65/248 (26%), Positives = 80/248 (32%), Gaps = 63/248 (25%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P     P P  G    N   G    PG   G+ P G   +Q P     +    +P     
Sbjct: 54  PGKPQGPPPQGG----NQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPE--RPPPQGG 107

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPE 744
           N S     P    E    +GG            ++H   P    P+ P P  G Q   P 
Sbjct: 108 NQSQGTPPPPGKPERPPPQGGN-----------QSHRPPPPPGKPERPPPQGGNQSQGPP 156

Query: 745 PLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQG--PAEPI 802
           P           G+P  PP    N+   A S         PP K    P ++G  P  P 
Sbjct: 157 P---------HPGKPEGPPPQEGNKSRSARS---------PPGKPQGPPQQEGNKPQGPP 198

Query: 803 PPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDS 862
           PPG      +P   GP  A   P+ P  PP  K        P+GP   P G R       
Sbjct: 199 PPG------KPQ--GPPPAGGNPQQPQAPPAGK--------PQGPPPPPQGGRP------ 236

Query: 863 VPERPRPA 870
               PRPA
Sbjct: 237 ----PRPA 240



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 9/98 (9%)

Query: 339 PDPRKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQP-- 396
           P P K       G +  Q  P     PE+ P       P  G  + R P  PG P +P  
Sbjct: 94  PHPGKPERPPPQGGNQSQGTPPPPGKPERPP-------PQGGNQSHRPPPPPGKPERPPP 146

Query: 397 ETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQ 434
           +  + SQGP   P  P     +        R P G  Q
Sbjct: 147 QGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQ 184


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 77/287 (26%), Positives = 99/287 (34%), Gaps = 38/287 (13%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P V+P+  P P   P +     + VP   P   P    AT  P A         P + A 
Sbjct: 683 PPVSPSATP-PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA--------PPPLAAP 733

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPE 744
              V    PA            R         L+    SP    P  P+  P PQ  AP 
Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP-SPPASLPMSPLAKPPPQ--APP 790

Query: 745 PLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKAS---ALPVEQGPAEP 801
            L         Q  P PP   P   P   S++ P SP+  PP +A    A P+ Q P  P
Sbjct: 791 ALATP----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846

Query: 802 IPPGVASGGLRPDALGPTTAHHGPR--------HPPKPPRSKATERPGQEPEGPGATPAG 853
                     RP   GP T+  GPR         PP P RS ++   G +  G  ++   
Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 906

Query: 854 ERDD-QSPDSVPE------RPRPADRRLCLPCV----DASPLPGRTA 889
             ++ +  DS PE       P  A+   C P       A PL  R A
Sbjct: 907 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 953



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 79/286 (27%), Positives = 97/286 (33%), Gaps = 26/286 (9%)

Query: 628 APAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNAS 687
           A  PE +P   P  S       P   P     GE A   PA  TS      P    + + 
Sbjct: 68  ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP--PAKNTSPGPVSSP---GRASG 122

Query: 688 VARDQPA------LAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGA 741
             R  P       ++ EE+  RG   E      LS  A       +   GP PG      
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR------RDTSGPTPGTPSPAM 176

Query: 742 APEPLGASVQ----RDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQG 797
           A     A  +    R +   RP PP + P      AS  +   P PA   + SA    Q 
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 798 PAEPIPPGVASGGLRPDALGPTT--AHHGPRHP--PKPPRSKATERPGQEPEGPGATPAG 853
           PA       A+    P   GP+       P HP  PKP   +A   P   P    A PA 
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 854 ERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATRL 899
                SP + P       R +  P   A+PLP  T  PS   AT L
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPA-TLPPSPPLATPL 341



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 18/133 (13%)

Query: 723 SPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV 782
           SP    P  P+  P PQ  AP  L   + +      P PP QAP + P    ++ P SP 
Sbjct: 635 SPPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQAPFSPP----ASPPVSPS 688

Query: 783 PAPPTKA----SALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATE 838
             PP++A    +A P++  P+ P  P ++     P    P  A    + PP PP S    
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS---- 744

Query: 839 RPGQEPEGPGATP 851
                P  P ATP
Sbjct: 745 ----PPMSPSATP 753



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 49/195 (25%), Positives = 71/195 (36%), Gaps = 19/195 (9%)

Query: 723 SPSLKTPDGPVPGP-GPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSP 781
           +P    P  PV  P  P  + P    A+    +      PP Q P + P     +   +P
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722

Query: 782 VPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRS---KATE 838
            P  P   +A P++  P+ P  P ++     P  + P  A    + PP PP S       
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 839 RPGQEPEGPGATPAGERDDQSPDSVP-ERPRPADRRLCL----------PCVDASPL--- 884
           +P  +     ATP  +     P S P + P      L +          P V A+PL   
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842

Query: 885 -PGRTACPSLQEATR 898
            P   A P+LQ   R
Sbjct: 843 PPSPPASPTLQAPRR 857



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 49/171 (28%), Positives = 61/171 (35%), Gaps = 17/171 (9%)

Query: 722 GSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASS------ 775
           G PS   P  P+  P PQ  AP  L A     +    P  PP +P   P   +       
Sbjct: 605 GLPS--PPLSPLATPPPQ--APPXL-ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659

Query: 776 --AAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPR 833
              AP SP P+PP +A   P     + P+ P        P +L        P  P  PP 
Sbjct: 660 LLQAPFSPPPSPPVQA---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716

Query: 834 SKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPL 884
           S +   P Q P  P A P  +     P S P  P         P + A PL
Sbjct: 717 SPSATPPPQAPP-PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 54/185 (29%), Positives = 66/185 (35%), Gaps = 37/185 (20%)

Query: 723 SPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV 782
           +P L+TP  P P P P  A P PL              PPP+ P+      S A P  P 
Sbjct: 555 TPHLETP--PCPAPCPLQAPPSPLTT------------PPPETPS------SIATP--PP 592

Query: 783 PAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSK-ATERPG 841
            APP  AS  P++  P+ P+ P        P  L        P  P  PP S  AT  P 
Sbjct: 593 QAPPALASP-PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651

Query: 842 ----------QEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPL---PGRT 888
                     Q P  P  +P  +     P S P  P         P + A PL   P   
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711

Query: 889 ACPSL 893
           A P +
Sbjct: 712 ASPPM 716



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 55/228 (24%), Positives = 77/228 (33%), Gaps = 33/228 (14%)

Query: 627  VAPAPEPSPGFLPVNSDTGLVAVPGP---VPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
            ++P  +P P   P  +   L A+P P    PGQ P    A+   +   +      P++ A
Sbjct: 778  MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837

Query: 684  QNASVARDQPALAQEESEERG---GQREGEGEEKLSLEAHAGSPS--LKTPDGPVPGPGP 738
                V    PA    ++  R    G        +L+L    G P    ++P   + GP  
Sbjct: 838  PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897

Query: 739  QG------AAPEPLGASVQRDSAQGRPCPPPQA------PANQPEG-----ASSAAPGSP 781
             G      + PE L              PPP A      PA    G     A   APG+P
Sbjct: 898  AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957

Query: 782  VPAPPTKA-------SALPVEQGPAEPIP-PGVASGGLRPDALGPTTA 821
            +P PP            +   +GP    P PG    G  P   G   A
Sbjct: 958  LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 1005



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 30/244 (12%)

Query: 183 SSCRVCRSLSAVGRRVLSIESFG-ALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLP 241
           ++ RV  +  AVGR+ L+  + G     + ES+ R       AGP R  G  S +P   P
Sbjct: 42  AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR-------AGPTRSAGTSSRNPASRP 94

Query: 242 TPEG------PESETSRGPRASPTKALLSTPVRNGESHSREGLAGLVLDAERTLGE-LDR 294
              G      P   TS GP +SP +A  S   R G      G  GL + AE T+      
Sbjct: 95  PASGRGERAPPAKNTSPGPVSSPGRA--SGTTRPGPL----GQKGLRISAEETVARGKAT 148

Query: 295 DALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPDPRKAFLDRKNGLSS 354
           +A +RS L       R  +  P      P    +S+   +E+  P P  +   R      
Sbjct: 149 EAPKRSAL---SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 355 FQAQPKCRLWPEQEPEHQLGRVPCAG----RSTDRGPGVPGSP-GQPETSHPS-QGPAEA 408
            ++          EP     R P AG    R   R      +P   P  S PS +G   A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 409 PADP 412
           PA P
Sbjct: 266 PAHP 269



 Score = 36.2 bits (82), Expect = 0.29
 Identities = 59/276 (21%), Positives = 93/276 (33%), Gaps = 35/276 (12%)

Query: 625 PSVAPAPEPSPGFLPVNSDTG-LVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLA 683
           PS  P P        V+S +      P P   + P      Q PA+ +  ++       A
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 684 QNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSL-KTPDGPVPGPGPQGA- 741
           ++   AR  P      S+ +    +     +++      +P+L      P+  P P G  
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 742 ---------APEPLGASVQRDSAQGRPCPP--------------PQAPANQPEGASSAAP 778
                    A  PL A++        P P               P  PA  P  A  +  
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT 373

Query: 779 GSPVPAPPTKASALPVE-----QGPAEPIPPG-VASGGLR-PDALGPTTAHHGPRHPPKP 831
             P+ APP+  +  P++       P+   PP  +A   L+   +LG  T           
Sbjct: 374 TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS 433

Query: 832 PRSKATERPGQEPEGPGATPAGERDDQSPDSVPERP 867
           PR   T+     P  P +TP      Q+P S+P  P
Sbjct: 434 PRQ--TQASLTSPSRPASTPPDSPPLQAPLSLPASP 467



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 41/159 (25%), Positives = 54/159 (33%), Gaps = 36/159 (22%)

Query: 715 LSLEAHAGSPSLKTPDGPVPGPGPQGA---APEPL---GASVQRDSAQGRPCPPPQAPAN 768
           L  ++    PSL+TP   +  P  +     AP PL    A +     +  PCP P     
Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP----- 566

Query: 769 QPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHP 828
                   AP SP+  PP +  +      P    PP +AS  L+                
Sbjct: 567 ----CPLQAPPSPLTTPPPETPSSIAT--PPPQAPPALASPPLQG--------------L 606

Query: 829 PKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERP 867
           P PP S     P Q P      P      Q+P S P  P
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPL-----QAPPSPPASP 640



 Score = 35.0 bits (79), Expect = 0.64
 Identities = 48/173 (27%), Positives = 58/173 (33%), Gaps = 20/173 (11%)

Query: 717 LEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGR--PCPPPQAPANQPEGAS 774
           L   AG     T     P  GP  +A         R  A GR    PP +  +  P  + 
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117

Query: 775 SAAPGSPVPAPPTK-----ASALPVEQGPAEPIPPGVA-SGGLRPDALGPTTAHHGPRHP 828
             A G+  P P  +     ++   V +G A   P   A S G R D  GPT    G   P
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP---GTPSP 174

Query: 829 PKPPRSKAT--------ERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRR 873
               RS+A           P   P  P   P       S  S  E P PA RR
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-PSPAARR 226



 Score = 31.6 bits (70), Expect = 7.1
 Identities = 46/173 (26%), Positives = 51/173 (29%), Gaps = 48/173 (27%)

Query: 738 PQGAAPEPLGASVQRDSAQGRPCPP----------------------------------- 762
           P   AP   G    R     RP PP                                   
Sbjct: 17  PAARAP---GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 763 -PQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPI-PPGVASGGLRPDALGPTT 820
            P+A   +  G SS  P S  PA      A P +     P+  PG ASG  RP  LG   
Sbjct: 74  APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 821 AHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRR 873
                       R KATE P +     GA     RD   P   P  P PA  R
Sbjct: 134 LRISAEE--TVARGKATEAPKRSALSAGA----RRDTSGP--TPGTPSPAMAR 178


>gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Homo
            sapiens]
          Length = 730

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 49/173 (28%), Positives = 77/173 (44%), Gaps = 11/173 (6%)

Query: 1537 LLRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV 1596
            LL+  ++V  WVA EI+       +V L+ KF+ IA  C  QRN  +   I+ GL   +V
Sbjct: 539  LLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASV 598

Query: 1597 -RQSPAWRILPAKIAEVMEELKAVEVFLKSDSL---CLMEGRRFRAQPTLPSAHLLAMHI 1652
             R S  W  +P K  ++  EL++    L   SL      +  +    P +P   LL   +
Sbjct: 599  SRLSQTWEKIPGKFKKLFSELES----LTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDV 654

Query: 1653 QQLETGGFTMTNGAHRWSKLRNIAKVVSQVHAFQENPY-TFSP--DPKLQSYL 1702
              +  G  T  +    + KL  IA  V  +   + N +   SP    +L+SY+
Sbjct: 655  TFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGDLSPKEHQELKSYV 707


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 56/206 (27%), Positives = 74/206 (35%), Gaps = 18/206 (8%)

Query: 692 QPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQ 751
           QP  A+   + R  ++  EG    +  A  G+ +L     P P   P+    E     V+
Sbjct: 445 QPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSEN---GVE 501

Query: 752 RDSA------QGRPCPPPQAPANQPEGASSAAPG-----SPVPAPPTKASALPVEQGPAE 800
            D+       +G P  P + P   P G +   P      +P P P   A   P E     
Sbjct: 502 EDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 561

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSP 860
           P P      G  P      T   GP  P  P R +  E P + P    A PAG+   +SP
Sbjct: 562 PGPRPAGPAGDEPAESPSETP--GPS-PAGPTRDEPAESPSETPGPRPAGPAGDEPAESP 618

Query: 861 DSVPERPRPADRRLCLPCVDASPLPG 886
              P  PRPA      P    S  PG
Sbjct: 619 SETP-GPRPAGPAGDEPAESPSETPG 643



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 59/180 (32%), Positives = 73/180 (40%), Gaps = 41/180 (22%)

Query: 697 QEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQG-AAPEPLGASVQRDSA 755
           +E++E R G +EG            GSPS        PGP P G A  EP       +S 
Sbjct: 501 EEDTEGRTGPKEGT----------PGSPS------ETPGPSPAGPAGDEPA------ESP 538

Query: 756 QGRPCPPPQAPA-NQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPD 814
              P P P  PA ++P  + S  PG   P P   A   P E  P+E   PG       P 
Sbjct: 539 SETPGPRPAGPAGDEPAESPSETPG---PRPAGPAGDEPAES-PSET--PG-------PS 585

Query: 815 ALGPTTAH--HGPRHPPKP-PRSKATERPGQEP-EGPGATPAGERDDQSPDSVPERPRPA 870
             GPT       P   P P P   A + P + P E PG  PAG   D+  +S  E P P+
Sbjct: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS 645



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 60/196 (30%), Positives = 75/196 (38%), Gaps = 35/196 (17%)

Query: 623 LKPSVAPAPEPSPGFLP--VNSDT--------GLVAVPGPVPGQHPCGEEATQLPAAFTS 672
           L  S AP+  P  G     V  DT        G    P   PG  P G    + PA   S
Sbjct: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDE-PAESPS 539

Query: 673 EATHFKPIVLAQNASVARDQPALAQEESE-ERGGQREGEGEEKLSLEAHAGSPSLKTPDG 731
           E    +P      A  A D+PA +  E+   R     G+   +   E    SP+  T D 
Sbjct: 540 ETPGPRP------AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDE 593

Query: 732 PV------PGPGPQG-AAPEPLGASVQRDSAQGRPCPPPQAPA-NQPEGASSAAPGSPVP 783
           P       PGP P G A  EP       +S    P P P  PA ++P  + S  PG P P
Sbjct: 594 PAESPSETPGPRPAGPAGDEP------AESPSETPGPRPAGPAGDEPAESPSETPG-PSP 646

Query: 784 APPTKASALPVEQGPA 799
           A PT+    P + G A
Sbjct: 647 AGPTRDE--PAKAGEA 660



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 60/225 (26%), Positives = 84/225 (37%), Gaps = 23/225 (10%)

Query: 690 RDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAP-EPLGA 748
           +D   L + + +E GG  E   E     E+      L   + P   PGPQ A+  E +  
Sbjct: 353 QDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIAL 412

Query: 749 SVQRDS-AQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKA--SALPVEQGPAEPIPPG 805
           +++  + +QG      Q    Q  G +      P+ A           V++G  +     
Sbjct: 413 NLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSA--A 470

Query: 806 VASGGLRPDALGPTTAHHGPRHPPKPPRSKATER------------PGQEPEGPGATPAG 853
           VASGG +  AL  + A  G  HP         E             PG   E PG +PAG
Sbjct: 471 VASGGAQTLALAGSPAPSG--HPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAG 528

Query: 854 ERDDQSPDSVPER--PRPADRRLCLPCVDASPLPG-RTACPSLQE 895
              D+  +S  E   PRPA      P    S  PG R A P+  E
Sbjct: 529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDE 573



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 16/121 (13%)

Query: 964  SPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMARTSSRAPCSPTSVSDVDSD 1023
            +P P  A  AG   E ++SP      RP+     +   + + T   +P  PT     +S 
Sbjct: 541  TPGPRPAGPAGD--EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESP 598

Query: 1024 ALSRGNFEVGFRPQRSVKAERAQQPEAGEDRRPAGGASDVEAVTRLARSKGVGPALSPGP 1083
            + + G      RP      E A+ P      RPAG A D  A +         P+ +PGP
Sbjct: 599  SETPGP-----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---------PSETPGP 644

Query: 1084 A 1084
            +
Sbjct: 645  S 645



 Score = 32.3 bits (72), Expect = 4.2
 Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 3/76 (3%)

Query: 365 PEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADP-RD--ASGEAQT 421
           P   P    G  P    S   GP   G  G      PS+ P  +PA P RD  A   ++T
Sbjct: 542 PGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET 601

Query: 422 PRDDERIPEGARQLES 437
           P      P G    ES
Sbjct: 602 PGPRPAGPAGDEPAES 617


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 76/295 (25%), Positives = 102/295 (34%), Gaps = 66/295 (22%)

Query: 561  DMARRSAPERPSAAEA-------IKVCGSYLLQRGMDSRKILAHLRASICQVYQEEETIS 613
            D   R  P  PS  EA        KV  S  L+R + +++             Q+E    
Sbjct: 1093 DGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQ------------NQQENVKF 1140

Query: 614  LQNAFSVVELKPSVAP---APEPSPGFLPVNSDTGLVA------------VPGPVPGQHP 658
            +      V+ +P        PEP P     ++ TG V             +P P P   P
Sbjct: 1141 ILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEP 1200

Query: 659  CGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLE 718
               +   LP     E    KP            +P L Q   + +G        +K+ L 
Sbjct: 1201 PPTDLAHLPPLPPPEGEARKPA-----KPPVSPKPVLTQPVPKLQGSPTPTS--KKVPLP 1253

Query: 719  AHAGSPSLK----TPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGAS 774
               GSP +K    TP    P P P   AP+P+ A     S    P P P +PA QP  A 
Sbjct: 1254 G-PGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAP-SPARQPPAAL 1311

Query: 775  SAAPGSP-------------------VPAPPTKASALPVEQGPAEPIPPGVASGG 810
            +  PG+P                   VPA P +A+A       A P PP  AS G
Sbjct: 1312 AKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPG 1366



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 70/267 (26%), Positives = 94/267 (35%), Gaps = 34/267 (12%)

Query: 629 PAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASV 688
           P PEP+P                P        E + +L AA T  A    P     ++ +
Sbjct: 635 PPPEPTPA-----------DCQSPKMTTFQDSELSDELQAAMTGPA-EVGPTTEKPSSHL 682

Query: 689 ARDQPALAQEESEERGGQREGEGEEKLSLEAHAG--SPSLKTPD-----GPVPGPGPQGA 741
                A  +++S   G  R     ++L  +   G  SP  ++ +     GP PG  P+ A
Sbjct: 683 PPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREA 742

Query: 742 APEPLGASVQRDSAQGRPCPPPQAPANQPEGASS-AAPGSPVPAPPTKASALPVEQGPAE 800
            P   G S++R S    P  P Q     P G S    P +P    P    AL    GPA 
Sbjct: 743 RPGRHGHSIKRASVPPVPGKPRQV---LPPGTSHFTPPQTPTKTRPGSPQALGGPHGPA- 798

Query: 801 PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSP 860
              P  A     P  L PT     PR  P+ P  +       +P        GE    +P
Sbjct: 799 ---PATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQP------VEGEVGPAAP 849

Query: 861 DSVPERPRPADRRLCLPCVDASPLPGR 887
              P     A   LCLP  +A   PGR
Sbjct: 850 GPAPPPVPTAVPTLCLP-PEADAEPGR 875



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 67/274 (24%), Positives = 94/274 (34%), Gaps = 27/274 (9%)

Query: 629  PAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASV 688
            P     PG   V   TG     GP  G+   G E    P A    +   K  + A+    
Sbjct: 1081 PGESADPGPF-VEDGTGRQRPRGPSKGE--AGVEGP--PLAKVEASATLKRRIRAKQNQQ 1135

Query: 689  ARDQPALAQEESEER---GGQREGEGEEKLSLEA-HAGSPSLKT-PDGPVPGPGPQGAAP 743
               +  L + ++ +R     +RE   E    L   H G+ +++  P     GP P+   P
Sbjct: 1136 ENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGP-PELPPP 1194

Query: 744  EPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPA---PPTKASALPVEQGPAE 800
             P       D A   P PPP+  A +P    +  P SP P    P  K    P       
Sbjct: 1195 PPPAEPPPTDLAHLPPLPPPEGEARKP----AKPPVSPKPVLTQPVPKLQGSPTPTSKKV 1250

Query: 801  PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSP 860
            P+P   +    R     P  +   P  P  P   KA         GP   P+  R  Q P
Sbjct: 1251 PLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPAR--QPP 1308

Query: 861  DSVPERPRPADRRLCLPCVDASPL-PGRTACPSL 893
             ++ + P         P + ASP  P     P+L
Sbjct: 1309 AALAKPPGTP------PSLGASPAKPPSPGAPAL 1336


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 81/295 (27%), Positives = 98/295 (33%), Gaps = 60/295 (20%)

Query: 625  PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
            P   P P   PG        GL  + GP       GE     PA F              
Sbjct: 766  PIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF-------------- 811

Query: 685  NASVARDQPALAQEESEERG-GQREGEGEEKLSLEAHAGSPSLKTP---DGPVPGPGPQG 740
                    P    +  E  G G+R   GE+        G P +  P    GP   PGPQG
Sbjct: 812  --------PGAPGQNGEPGGKGERGAPGEK-----GEGGPPGVAGPPGGSGPAGPPGPQG 858

Query: 741  AAPE---PLGASVQR-DSAQGRPCPP-------PQAPANQP-------EGASSAAPGSPV 782
               E   P G        A+G P PP       P  P+  P          ++ APGSP 
Sbjct: 859  VKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPG 918

Query: 783  PAPPTKASALPVEQG-PAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPG 841
             + P   +  P E+G P    PPG A G L    +       GP   P P  S   +   
Sbjct: 919  VSGPKGDAGQPGEKGSPGAQGPPG-APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977

Query: 842  QEPEGPGATP-AGERDDQSPDSVPERPRPADRRLCLPCVDASP----LPGRTACP 891
             E   PGA   +GER    P  +P     A      P  D +P    LPGR   P
Sbjct: 978  GESGKPGANGLSGERGPPGPQGLPGLAGTAGE----PGRDGNPGSDGLPGRDGSP 1028



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 73/255 (28%), Positives = 86/255 (33%), Gaps = 50/255 (19%)

Query: 625  PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
            P   P P  SPG   V  ++G     G    + P G +   LP              LA 
Sbjct: 961  PPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG--LPG-------------LAG 1005

Query: 685  NASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPSLKTPDGPVPGPGPQGAAP 743
             A           +    R G   G+G+   +    A G+P    P GPV   G  G   
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 744  E--PLGASVQRDSAQGRPCPPPQAPANQP-----EGASS-----------AAPGSPVPAP 785
            E  P G +     A  R  P PQ P          GA+             APGSP PA 
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAG 1125

Query: 786  PTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATER------ 839
               A   P   GP  P+ P   SG   P     T+ H GP  PP  PR    ER      
Sbjct: 1126 QQGAIGSPGPAGPRGPVGP---SG---PPGKDGTSGHPGPIGPP-GPRGNRGERGSEGSP 1178

Query: 840  --PGQE-PEGPGATP 851
              PGQ  P GP   P
Sbjct: 1179 GHPGQPGPPGPPGAP 1193



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 67/254 (26%), Positives = 83/254 (32%), Gaps = 25/254 (9%)

Query: 629 PAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTS-EATHFKPIVLAQNAS 687
           P P+  PG    N +TG    PGP       G+     P        T   P    +N  
Sbjct: 602 PGPQGPPG---KNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP---GENGK 655

Query: 688 VARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKT---PDGPVPG------PGP 738
                P          GG+ +     +      AG+P L+    P GP  G      PGP
Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715

Query: 739 QGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEG-ASSAAPGSPVPAPPTKASALPVEQG 797
            GAA  P G         G   P P+    +P G  +   PG   P  PT     P   G
Sbjct: 716 PGAAGTP-GLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP---G 771

Query: 798 PA-EPIPPGVASGGLRPDALGP--TTAHHGPRHPPKPPRSKATERPGQEPEGPGATPA-G 853
           PA +P   G       P   GP  +    G   PP P           EP G G   A G
Sbjct: 772 PAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG 831

Query: 854 ERDDQSPDSVPERP 867
           E+ +  P  V   P
Sbjct: 832 EKGEGGPPGVAGPP 845



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 42/147 (28%), Positives = 47/147 (31%), Gaps = 31/147 (21%)

Query: 729 PDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSP-VPAPPT 787
           P  P  G GPQG   +P                PP  P    +      PGSP  P PP 
Sbjct: 95  PTRPPNGQGPQGPKGDP---------------GPPGIPGRNGDPGIPGQPGSPGSPGPPG 139

Query: 788 KASALPVEQGPAEP------IPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPG 841
              + P       P      +  GVA GGL          + GP  PP PP    T    
Sbjct: 140 ICESCPTGPQNYSPQYDSYDVKSGVAVGGL--------AGYPGPAGPPGPPGPPGTSGHP 191

Query: 842 QEPEGPG-ATPAGERDDQSPDSVPERP 867
             P  PG   P GE     P   P  P
Sbjct: 192 GSPGSPGYQGPPGEPGQAGPSGPPGPP 218



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 43/156 (27%), Positives = 52/156 (33%), Gaps = 23/156 (14%)

Query: 722 GSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPP-PQAPANQP---------- 770
           G P ++   G   GPG  G  P P G+  +     GRP PP P  P  QP          
Sbjct: 531 GGPGMRGMPGSPGGPGSDGK-PGPPGSQGE----SGRPGPPGPSGPRGQPGVMGFPGPKG 585

Query: 771 ------EGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHG 824
                 +      PG P P  P   +     QGP  P  PG   G   P          G
Sbjct: 586 NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG 645

Query: 825 PRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSP 860
              PP          P  +   PGA P G+ D  +P
Sbjct: 646 TGGPPGENGKPGEPGPKGDAGAPGA-PGGKGDAGAP 680



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 52/179 (29%), Positives = 63/179 (35%), Gaps = 41/179 (22%)

Query: 722 GSPSLKTPDGPVPGPGPQGA-----APEPLGASVQRDSAQGRPCPP--PQAPANQPEGAS 774
           GSP  K   GP   PG  GA      P P G +     AQG P PP    +P  + E   
Sbjct: 345 GSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA----GAQGPPGPPGINGSPGGKGEMGP 400

Query: 775 SAAPGSPVPAPPTKASALPVEQGPAEPI----PPGVASGGLRPDALGPTTAHHGPRHP-- 828
           +  PG+P          L   +GP  P      PG+  G   P   G      GPR    
Sbjct: 401 AGIPGAP---------GLMGARGPPGPAGANGAPGLRGGAGEPGKNG-AKGEPGPRGERG 450

Query: 829 ----PKPPRSKATERPGQEPEGPGAT----PAGE------RDDQSPDSVPERPRPADRR 873
               P  P +K  +     P  PGA      AGE      R    P+ +P    PA  R
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER 509



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 43/133 (32%), Positives = 52/133 (39%), Gaps = 16/133 (12%)

Query: 722 GSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGR-PCPPPQAPANQPEGASSAAPGS 780
           G P  K  DG    PG  GA   P GA+ +R +   R P  P   P  +       APG 
Sbjct: 456 GVPGAKGEDGKDGSPGEPGANGLP-GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG- 513

Query: 781 PVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKA-TER 839
             PA P  A+  P   G    +P G    G+     GP     G    P PP S+  + R
Sbjct: 514 --PAGPRGAAGEPGRDG----VPGGPGMRGMPGSPGGP-----GSDGKPGPPGSQGESGR 562

Query: 840 PGQE-PEGPGATP 851
           PG   P GP   P
Sbjct: 563 PGPPGPSGPRGQP 575



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 53/184 (28%), Positives = 63/184 (34%), Gaps = 43/184 (23%)

Query: 720 HAGSPSLKTPDGPVPGPGPQGAA--PEPLGA-----SVQRDSAQGRPCPPPQAPANQPEG 772
           H GSP      GP   PG  G +  P P GA        +D   GRP  P +     P G
Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249

Query: 773 ASSAA--PGSP-----------------VPAPPTKA-SALPVEQGPAEPIPPGVASGGL- 811
               A  PG P                   AP  K  + LP E G   P+ P  A G   
Sbjct: 250 IKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG 309

Query: 812 RPDALGPTTAH--------HGPRHPPKPPRSKA-TERPGQEPE-GPGATPA-----GERD 856
           RP   G   A          G   PP PP +      PG + E GP  +P      G+R 
Sbjct: 310 RPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRG 369

Query: 857 DQSP 860
           +  P
Sbjct: 370 EPGP 373



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 42/139 (30%), Positives = 49/139 (35%), Gaps = 19/139 (13%)

Query: 722 GSPSLKTPDGPVPG--PGPQGAAPEPLGASVQRDSAQGR------PCPPPQAPANQPEGA 773
           GSP    P G       GPQ  +P+     V+   A G       P  PP  P       
Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189

Query: 774 SSAAPGSP-VPAPPTKASALPVEQGPA-EPIPPGV--ASGGLRPDALGPTTAHHGPRHPP 829
              +PGSP    PP +    P + GP+  P PPG    SG    D         G R  P
Sbjct: 190 HPGSPGSPGYQGPPGE----PGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLP 245

Query: 830 KPPRSKATERPGQEPEGPG 848
            PP  K    P   P  PG
Sbjct: 246 GPPGIKG---PAGIPGFPG 261



 Score = 32.0 bits (71), Expect = 5.4
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 4/46 (8%)

Query: 221 PGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTKALLSTP 266
           PG AGP  PPG P T       P  P S   +GP   P +A  S P
Sbjct: 173 PGPAGPPGPPGPPGTSGH----PGSPGSPGYQGPPGEPGQAGPSGP 214



 Score = 31.6 bits (70), Expect = 7.1
 Identities = 44/151 (29%), Positives = 48/151 (31%), Gaps = 11/151 (7%)

Query: 721 AGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS 780
           AG P    P GP   PG  G    P          QG P  P QA  + P G   A  G 
Sbjct: 170 AGYPGPAGPPGPPGPPGTSGHPGSP-----GSPGYQGPPGEPGQAGPSGPPGPPGAI-GP 223

Query: 781 PVPAPPTKASALPVEQGP-AEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATER 839
             PA     S  P   G    P PPG+      P   G    H G     +      T  
Sbjct: 224 SGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPG-MKGHRG--FDGRNGEKGETGA 280

Query: 840 PGQEPEGPGATPAGERDDQSPDSVP-ERPRP 869
           PG + E       G      P   P ER RP
Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRP 311



 Score = 31.6 bits (70), Expect = 7.1
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 1/31 (3%)

Query: 217 ERPAPGNAGPRRPPG-DPSTDPEVLPTPEGP 246
           ER  PG  GP+ PPG +  T P+  P P GP
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGP 625



 Score = 31.2 bits (69), Expect = 9.3
 Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 8/49 (16%)

Query: 217 ERPAPGNAGPRRPPGDPSTD-------PEVLP-TPEGPESETSRGPRAS 257
           ER APG AGPR   G+P  D          +P +P GP S+   GP  S
Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556



 Score = 31.2 bits (69), Expect = 9.3
 Identities = 27/73 (36%), Positives = 29/73 (39%), Gaps = 21/73 (28%)

Query: 374  GRVPCAGRSTDRG----PGVPGSPGQPETSHPSQGPA--------EAPADPRDASGEA-- 419
            GR    G   DRG    PG PG+PG P    P  GPA          PA P  A G A  
Sbjct: 1023 GRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP-VGPAGKSGDRGESGPAGPAGAPGPAGS 1081

Query: 420  ------QTPRDDE 426
                  Q PR D+
Sbjct: 1082 RGAPGPQGPRGDK 1094


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 48/153 (31%), Positives = 60/153 (39%), Gaps = 16/153 (10%)

Query: 729 PDGPVPGPG-PQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPT 787
           P GP P PG PQG  P+  G   Q     G+P  PP  P      +  + PG P   PP 
Sbjct: 47  PQGPPPPPGKPQGPPPQG-GNKPQGPPPPGKPQGPP--PQGDKSRSPRSPPGKPQGPPPQ 103

Query: 788 --KASALPVEQG--PAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQ- 842
             K    P + G  P  P PPG   G          +A   P  P  PP+ +     G  
Sbjct: 104 GGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 163

Query: 843 -----EPEGPGATPAGERDDQSPDSVPERPRPA 870
                 P+ P A PAG+   Q P   P+  RP+
Sbjct: 164 PPAGGNPQQPQAPPAGQ--PQGPPRPPQGGRPS 194



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 37/120 (30%), Positives = 49/120 (40%), Gaps = 8/120 (6%)

Query: 723 SPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV 782
           S S ++P G   GP PQG  P+  G   Q  +    P PPP  P   P  A   +     
Sbjct: 87  SRSPRSPPGKPQGPPPQGGKPQ--GPPPQGGNKPQGP-PPPGKPQGPP--AQGGSKSQSA 141

Query: 783 PAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQ 842
            +PP K    P ++G     PP  A G  +     P      P+ PP+PP+     RP Q
Sbjct: 142 RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ---PQGPPRPPQGGRPSRPPQ 198



 Score = 31.6 bits (70), Expect = 7.1
 Identities = 16/50 (32%), Positives = 20/50 (40%)

Query: 226 PRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTKALLSTPVRNGESHSR 275
           PR PPG P   P     P+GP  +    P+  P       P   G S S+
Sbjct: 90  PRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ 139


>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform b
            [Homo sapiens]
          Length = 867

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 4/159 (2%)

Query: 1538 LRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV- 1596
            LR  +++  WV  EI        +V LL KF+ IA  C E +N  +   I+ GL ++AV 
Sbjct: 673  LRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVS 732

Query: 1597 RQSPAWRILPAKIAEVMEELKAVEVFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLE 1656
            R +  W  LP+K  +   E +++    ++     +   +    P +P   LL   +    
Sbjct: 733  RLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLE-PPLIPFMPLLIKDMTFTH 791

Query: 1657 TGGFTMTNGAHRWSKLRNIAKVVSQVHAFQENPYTFSPD 1695
             G  T  +    + K+R IA     V  ++  P  F+PD
Sbjct: 792  EGNKTFIDNLVNFEKMRMIANTARTVRYYRSQP--FNPD 828


>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform a
            [Homo sapiens]
          Length = 1011

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 4/159 (2%)

Query: 1538 LRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV- 1596
            LR  +++  WV  EI        +V LL KF+ IA  C E +N  +   I+ GL ++AV 
Sbjct: 817  LRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVS 876

Query: 1597 RQSPAWRILPAKIAEVMEELKAVEVFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLE 1656
            R +  W  LP+K  +   E +++    ++     +   +    P +P   LL   +    
Sbjct: 877  RLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLE-PPLIPFMPLLIKDMTFTH 935

Query: 1657 TGGFTMTNGAHRWSKLRNIAKVVSQVHAFQENPYTFSPD 1695
             G  T  +    + K+R IA     V  ++  P  F+PD
Sbjct: 936  EGNKTFIDNLVNFEKMRMIANTARTVRYYRSQP--FNPD 972


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/253 (28%), Positives = 94/253 (37%), Gaps = 29/253 (11%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAVPGPVP---GQHPCGEEATQLPAAFTSEATHFKPIVL 682
           S  PA  PS G   ++S  G   + G  P   GQ   G      P  F     H     +
Sbjct: 132 SPVPASGPSSG-PQMSSGPGGAPLDGADPQALGQQNRG------PTPFNQNQLHQLRAQI 184

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAA 742
                +AR QP L         G+R   G ++        S S   P GP PGPGP G  
Sbjct: 185 MAYKMLARGQP-LPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGP-GPGPGPGP-GPG 241

Query: 743 PEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV---PAPPTKASALPVEQGPA 799
           P P   +  R    G P  PP  P+  P G     PG P    P  P   +A P    P 
Sbjct: 242 PGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTST-PQ 300

Query: 800 EPIPP-GVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQ 858
           + IPP         P A+ P  +      P  PP+   T+ PGQ  +     P  ++  Q
Sbjct: 301 KLIPPQPTGRPSPAPPAVPPAAS------PVMPPQ---TQSPGQPAQPAPMVPLHQK--Q 349

Query: 859 SPDSVPERPRPAD 871
           S  +  ++PR  D
Sbjct: 350 SRITPIQKPRGLD 362



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 79/334 (23%)

Query: 624 KPSVAPAPEPSPGFL--------PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT 675
           +P  +P P PSPG +        P ++ + +   PGP    HP     TQ P  +  +  
Sbjct: 13  RPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPI---PTQGPGGYPQDNM 69

Query: 676 H--FKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHA-GSPS----LKT 728
           H   KP+       ++ D      +    R G   G G     ++ H+ G PS     + 
Sbjct: 70  HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129

Query: 729 PDGPVPGPGP-------QGAAPEPL-GASVQRDSAQGR-PCPPPQAPANQPEGASSA--- 776
              PVP  GP        G    PL GA  Q    Q R P P  Q   +Q      A   
Sbjct: 130 ASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKM 189

Query: 777 -APGSPVP----------------------APPTKASALPVEQGPAE-------PIPPGV 806
            A G P+P                       PP   SA     GP         P PP  
Sbjct: 190 LARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 807 ASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAT-PAGE-RDDQSPDSVP 864
           +    RP  +G      GP  PP  P       PGQ P GP    P G   +  +P S P
Sbjct: 250 S----RPHGMG------GPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTP 299

Query: 865 ER---PRPADRRLCLPCV---DASP-LPGRTACP 891
           ++   P+P  R    P      ASP +P +T  P
Sbjct: 300 QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSP 333


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 53/170 (31%), Positives = 63/170 (37%), Gaps = 19/170 (11%)

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPV-PGPGPQGA 741
           +Q A+ A     LA    E R       G   +S     GSP+     GP  P  G  GA
Sbjct: 31  SQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVS-----GSPAGAAGAGPAAPAEGAPGA 85

Query: 742 APEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEP 801
           APEP  A   R    G   P P +P      A  A P + +  PP  ++      G   P
Sbjct: 86  APEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSA------GSCAP 139

Query: 802 IPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATP 851
           +P   A       A GP  A  GP  P  P    A   PG  P GPG  P
Sbjct: 140 VPAAAAV------AAGPEPAPAGPAKPAGPAALAARAGPGPGP-GPGPGP 182



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 66/250 (26%), Positives = 87/250 (34%), Gaps = 20/250 (8%)

Query: 629 PAPEPSPGFL-PVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNAS 687
           P PE S G   PV +   + A P P P     G      PAA  + A             
Sbjct: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPA----GPAKPAGPAALAARAGPGPGPGPGPGPG 183

Query: 688 VARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLK-TPDGPVPG-PGPQGAAPEP 745
               +PA         G  +   G   L    HA +P++    +GP    P P+ AAP  
Sbjct: 184 PGPGKPA-------GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP-- 234

Query: 746 LGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPG 805
            G  +Q     G   PP  A  + P   + AAP +  P PP   + L   + P  P  P 
Sbjct: 235 -GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA--RPPGHPAGPP 291

Query: 806 VASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQE-PEGPGATPAGERDDQSPDSVP 864
            A+  + P A        G    P P         GQ  P    A PA     +SP  V 
Sbjct: 292 TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV 351

Query: 865 ERPRPADRRL 874
           +   PA + L
Sbjct: 352 QAAPPAAQTL 361



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 66/229 (28%), Positives = 81/229 (35%), Gaps = 33/229 (14%)

Query: 626 SVAPAPEPSPGFLPVNSDTGLVAV---PGPVPGQHPCGEEATQLPAAFTSEATHFKPIVL 682
           +VA  PEP+P      +    +A    PGP PG  P        PA   +  T      L
Sbjct: 145 AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQT------L 198

Query: 683 AQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPS-LKTPDGPVPGPGPQGA 741
             +A++     A A   S    G         L L   A   + ++TP        P  A
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAA-----LLPLPKPAAPGTVIQTPPFVGAAAPPAPA 253

Query: 742 APEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEP 801
           AP P  A      A   P PPP APA       +  PG P   PPT A        PA P
Sbjct: 254 APSPPAAPAPAAPAAAPP-PPPPAPA-----TLARPPGHPA-GPPTAA--------PAVP 298

Query: 802 IPPGVASGGLRPDALGPTTAHHGP---RHPPKPPRSKATERPGQEPEGP 847
            P    +GG    A  P  A  GP      P P  + A   PG + E P
Sbjct: 299 PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 52/189 (27%), Positives = 64/189 (33%), Gaps = 32/189 (16%)

Query: 629 PAPEPSPGFL------PVNSDTGLVAVPGPVPGQH--PCGEEATQLPAAFTSEATHFKPI 680
           P P P+P  L      P    T   AVP P   Q+    G      PAA        +P 
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP- 329

Query: 681 VLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQG 740
                A+ A   P + + ES +R  Q      + L     A S    T    V GP  QG
Sbjct: 330 --GPGAAAAAPAPGV-KAESPKRVVQAAPPAAQTL-----AASGPASTAASMVIGPTMQG 381

Query: 741 AAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPT-----KASALPVE 795
           A P P             P P P  P   P+GA+ A   S    P       +A+  P  
Sbjct: 382 ALPSPAAV----------PPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTV 431

Query: 796 QGPAEPIPP 804
             P  P PP
Sbjct: 432 LAPRLPQPP 440



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 60/214 (28%), Positives = 68/214 (31%), Gaps = 58/214 (27%)

Query: 722 GSPSLKTPDGP----VP-GPGPQGA-------------APEPLGASVQRDSAQGRPCPPP 763
           G P    P  P    VP GP P  A             AP P  A+V    A G P P P
Sbjct: 100 GGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV----AAG-PEPAP 154

Query: 764 QAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHH 823
             PA     A+ AA   P P P       P   GP +P  PG A       AL    +HH
Sbjct: 155 AGPAKPAGPAALAARAGPGPGPGPGPGPGP---GPGKPAGPGAAQTLNGSAAL--LNSHH 209

Query: 824 G--------------------PRHP----PKPPRSKATERPGQEPEGPGATPAGERDDQS 859
                                P  P      PP   A   P      P A PA      +
Sbjct: 210 AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA----PAA 265

Query: 860 PDSVPERPRPADRRLCLPCVDASPLPGRTACPSL 893
           P + P  P PA   L  P     P    TA P++
Sbjct: 266 PAAAPPPPPPAPATLARP--PGHPAGPPTAAPAV 297


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 70/280 (25%), Positives = 100/280 (35%), Gaps = 50/280 (17%)

Query: 625 PSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           P+ AP P P  G  P+ +   +     P PGQ  C  ++  LP           P  +  
Sbjct: 443 PTAAPYPTPPGG--PLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEM 500

Query: 685 NASVARDQPALAQEESEERGGQREGEG--------EEKLSL--EAHAGSPSLKTPDGPVP 734
            + +            E +GG +   G         EKL     +  GSP+L T +G   
Sbjct: 501 LSRLP-----FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD 555

Query: 735 GPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTK------ 788
                GA P   G +  + S  G P  PP      P    ++   SP+P+P T       
Sbjct: 556 ----PGAQPLFFGVAQPQVSPHGTPSLPP------PRVVGASPSESPLPSPATNTAGSTC 605

Query: 789 ASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPG 848
           +S  P+   PA P     +     P  LGP+   H P HP      + T  P   PE P 
Sbjct: 606 SSLSPMSSSPANP----SSEESQLPGPLGPSAFFHPPTHP------QETGSPFPSPEPPH 655

Query: 849 ATPAGERDDQSPDSVPERPRPAD---RRLCLPCVDASPLP 885
           + P        P+     P PAD         C++ +P P
Sbjct: 656 SLPT----HYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 62/213 (29%), Positives = 80/213 (37%), Gaps = 40/213 (18%)

Query: 696  AQEESEERGGQREGEGEEKLSLEAHAGSPSLKT-----PDGPVPGPGPQGAAPEPLGASV 750
            A    EE GG R G G    S +A   S SL+T       GP     P  A  +PL    
Sbjct: 1123 APANPEEPGGSRPGPGR---SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPT 1179

Query: 751  QRD-SAQGRPCPPPQAPANQPEGASSAAPGSP-----VPAPPTKAS----ALPVEQGPAE 800
              + S + RP       A +PE A  +AP S      + +PP   +    A P    P +
Sbjct: 1180 NTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQ 1239

Query: 801  PIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSP 860
            P P    +G  +P      TA HG         S  T   G    GPG T       Q+P
Sbjct: 1240 PPPSRHDTGTPKPSGSLANTAPHG---------SSPTPGVGSLLGGPGGT-------QAP 1283

Query: 861  DSVPERPRPADRRLCLPCVDASPL--PGRTACP 891
             S   +  PA +    P    +P+  P  TACP
Sbjct: 1284 VSHNSKDPPARQ----PGEFLAPVANPSSTACP 1312



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 126/521 (24%), Positives = 181/521 (34%), Gaps = 72/521 (13%)

Query: 622  ELKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEAT-----H 676
            EL P+    P  +P  L   +  G     GP  G  P G + T LPA    +       H
Sbjct: 1896 ELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGS-PGGVQVTTLPAVAGHQLGLEADGH 1954

Query: 677  FKPIVLAQNASVARDQPALAQEESEERGGQRE-------------GEGEEKLSLEAHAGS 723
            +  +  A+          L  E     GG                G  E  + LE   GS
Sbjct: 1955 WGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGS 2014

Query: 724  -PSLKTPDGPVPGPGPQGAAPEPLG----ASVQRDSAQGRPCPPPQAPA-NQPEGASSAA 777
              ++   +   P P P     E L     A+  R  ++GR      +P  N+P  A+  +
Sbjct: 2015 RAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDS 2074

Query: 778  PGSPVP-----AP-PTKASALPVEQGP---AEPI-PPGVASGGLRPDALGPTTAHHGPRH 827
            P   V      AP PT A+ +P   GP    +P+  P  A GGL     G   A    R 
Sbjct: 2075 PAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLG----GQLPASPSCRD 2130

Query: 828  PPKPPRSKATE---RPGQEPEGPGATPAGERDDQ--SPDSVPERPRPADRRL--CLPCVD 880
            PP P +  A      P +E +G  AT     +D   +P S+   P      L  CL   +
Sbjct: 2131 PPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGE 2190

Query: 881  ASPLPGRTACP--SLQEATRLIQEEFAFDGYL----DNGLEALIMGEYIFALKDLTFATF 934
             SPL   ++ P  S+   T     +   D  L    D+  E L            T    
Sbjct: 2191 GSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESP-----GRATSPPL 2245

Query: 935  CGAISEKFCDLYWDEKLLQNLFKVVNGQASPSPS-TAEEAGSQLEGSQSPRSPSSKRPS- 992
             GA+S                 +   G+  P P   +  A       + PR  SS  PS 
Sbjct: 2246 AGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSN 2305

Query: 993  LHRLGKEKPAMARTSSRAPCSPTSVSDVDSDALSRGNFEVGFRPQRSVKAERAQQPEAGE 1052
              RLG  +    +  +  P  P ++     D+ +    E+G     S + E    PE G 
Sbjct: 2306 TARLGHRE---GQAVTAVPTEPPTLQGAGPDSPACLEGEMG---TSSKEPEDPGTPETGR 2359

Query: 1053 DRRPAGGASDVEAVTRLARSKGVGPALSPG--PAGFQSCSP 1091
                  GA+ +  VT  +   G+G   +P    + FQS SP
Sbjct: 2360 -----SGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSP 2395



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 43/163 (26%), Positives = 58/163 (35%), Gaps = 9/163 (5%)

Query: 733 VPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASAL 792
           +PG  P+GA P  +   +Q       P  P Q P      A+    G+       +A  L
Sbjct: 1   MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60

Query: 793 PVEQGPAEPIPPGVASGGLRPDALGPTTAHHG-PRHPP-----KPPRSKATERPGQEPEG 846
           P E  P +     +    LR  A   T    G P+ PP     + P   A    G  P+ 
Sbjct: 61  P-EAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQR 119

Query: 847 PGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTA 889
                A  R   + D  PE P+    +  LP VD    PG  A
Sbjct: 120 YILGIASSRTKPTLDETPENPQLEAAQ--LPEVDTPQGPGTGA 160



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 65/258 (25%), Positives = 90/258 (34%), Gaps = 33/258 (12%)

Query: 629  PAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASV 688
            P P  SP    +    G  A+ G +  + P  E +   P     +A    P+  +     
Sbjct: 3523 PPPSLSPFPAALADGRGDCALDGAL--ERPENEASPGSPGPLLQQAL---PLGASLPRPG 3577

Query: 689  ARDQPALAQEESEERGGQREGEG------------EEKLSLEAHAGSPSLKTPDGPVPGP 736
            AR Q A  +       G+R   G            +  L  E    S  + +  GP  G 
Sbjct: 3578 ARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGP-RGT 3636

Query: 737  GPQGAAPEPLG--ASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV--------PAPP 786
              +G+A +P G  +S +  SA   P    + P +  +   S APG           PA P
Sbjct: 3637 FHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP 3696

Query: 787  TKASALPVEQGPAEPIPPGVASGGLRPD-ALGPTTAHHG--PRHPPKPPRSKATERPGQE 843
             KA   P  QG   P P     GG +P  A G   +     P  P  P RS A ER    
Sbjct: 3697 -KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755

Query: 844  PEGPGATPA-GERDDQSP 860
             +    T    E  +Q P
Sbjct: 3756 AQAKSCTKGPREAGEQGP 3773



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 56/198 (28%), Positives = 67/198 (33%), Gaps = 36/198 (18%)

Query: 696 AQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSA 755
           AQ  +EE G  R  +         +  SPS  TP  P PGP      P+  G S      
Sbjct: 171 AQPAAEELGFHRCFQEPPSSFTSTNYTSPSA-TPRPPAPGP------PQSRGTS------ 217

Query: 756 QGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDA 815
              P  P   P  Q  GA S  P +    P       P E    EPIP G   GG  P  
Sbjct: 218 ---PLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAE---PEPIPKGSRPGG-SPRG 270

Query: 816 LG---PTTAHHGPRHPPKPPRSKA---TERP----GQEPEGPGATPAGERDDQSPDSVPE 865
           +    P  A HG    P P        T  P      +P+G     A       P  +P 
Sbjct: 271 VSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP--LPT 328

Query: 866 RPRPADRRLCLPCVDASP 883
           +P P+     LPC    P
Sbjct: 329 QPAPSP----LPCYQGQP 342



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 92/398 (23%), Positives = 124/398 (31%), Gaps = 60/398 (15%)

Query: 627 VAPA-PEPSP-GFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQ 684
           V PA PEP P G  P  S  G V+   P P  H  G      PA     A    P+V A 
Sbjct: 250 VPPAEPEPIPKGSRPGGSPRG-VSFQFPFPALH--GASTKPFPADVAGHAFTNGPLVFAF 306

Query: 685 NASVARDQPALAQEESEERGGQREGEGEEKLS--LEAHAGSPS----LKTPDGPVPGPGP 738
           +      QP  A  E     G       +     L  + G P          G +  PG 
Sbjct: 307 H------QPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA 360

Query: 739 QGAAPEPLGASVQRDSAQGRPCPPPQAP--ANQPEGASSAAPGSPVPAPPTKASALPVEQ 796
             +AP P   S+ +   +  P  PP A        G  S+ P    P    +AS +    
Sbjct: 361 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420

Query: 797 GP--AEPIPPGVASGGLRPDALGPTTAHH-----GPRHPPKPPRSKATERPGQE---PEG 846
           GP   E   PG     L P    PT A +     GP    +         PGQ    P+ 
Sbjct: 421 GPPDTELAAPGPPPARL-PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS 479

Query: 847 -----PGATPAGERDDQSPDSVPERPRPA-------DRRLCLPCVDASPLPGRTACPSLQ 894
                P   P         + +   P PA         +  L     +P P R   P+++
Sbjct: 480 APLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGP-REKLPAVR 538

Query: 895 EATRLIQEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCDLYWDEKLLQN 954
            +       F ++G  D G + L  G                 +++     +    L   
Sbjct: 539 SSQGGSPALFTYNGMTDPGAQPLFFG-----------------VAQPQVSPHGTPSLPPP 581

Query: 955 LFKVVNGQASPSPSTAEEAGSQLEGSQSPRSPSSKRPS 992
                +   SP PS A         S SP S S   PS
Sbjct: 582 RVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPS 619



 Score = 37.7 bits (86), Expect = 0.099
 Identities = 41/167 (24%), Positives = 62/167 (37%), Gaps = 28/167 (16%)

Query: 724  PSLKTPDGPVPGPGPQGAA-PEPLGASVQRDSAQ--GRPCPPPQAPANQPEGASSAAPGS 780
            PS +    P PG    G + P+P    +Q ++A    +P  P ++PA  PE   + A   
Sbjct: 3702 PSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPA--PERLPARAQAK 3759

Query: 781  PVPAPPTKASALPVEQGPAEPIPP------------GVASGGLRPDALGPT-TAHHGPRH 827
                 P +A     EQGP   + P            G   G  R +++G    A   P  
Sbjct: 3760 SCTKGPREAG----EQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDK 3815

Query: 828  PPKPPRSKAT------ERPGQEPEGPGATPAGERDDQSPDSVPERPR 868
            PP+ PR +AT       +P    +     P  E+    P     + R
Sbjct: 3816 PPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDR 3862



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 60/274 (21%), Positives = 88/274 (32%), Gaps = 36/274 (13%)

Query: 636  GFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPAL 695
            GFLP      L A P P+P      E+  +L +  T      +     Q+ +   D   +
Sbjct: 815  GFLP-----SLAATPFPLPASDLDMEDDAKLDSLITEALNGME----YQSDNPEIDSSFI 865

Query: 696  AQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSA 755
                 EE  G R       L  +A        TP+   P P P  A P+P     Q    
Sbjct: 866  DVFADEEPSGPRGPSSGHPLKSKAGV------TPESKAPPPLP-AATPDP-----QTPRP 913

Query: 756  QGRPCPPPQAPANQPEGASSAAPGSPVPA------PPTKASALPVEQGPAEPIPPGVASG 809
              R CP    P  +  G +     +P            K     ++ G A       + G
Sbjct: 914  GDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAE--GSGSGG 971

Query: 810  GLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRP 869
            G R   L P         PP  PR   T+ PG   +     P          ++PE  R 
Sbjct: 972  GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAA-------ALPEETRS 1024

Query: 870  ADRRLCLPCVDASPLPGRTACPSLQEATRLIQEE 903
            + RR   P  D      R      +   +++Q++
Sbjct: 1025 SRRRRLPPRKDPRKRKARGGAWGKELILKIVQQK 1058



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 76/331 (22%), Positives = 111/331 (33%), Gaps = 65/331 (19%)

Query: 609 EETISLQNAFSV-VELKPSVAPAPEPSPGFLPVNSD-TGLVAVPGPVPGQHPCGEEATQL 666
           EE +    A+ +  +  PS  P  +  PG L  +SD +G ++ PG           A   
Sbjct: 315 EEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA----------AHSA 364

Query: 667 PAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGS--- 723
           P  F S++ H           +  ++P  AQ+      G      +     +A+  S   
Sbjct: 365 PRPF-SDSLH------KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVD 417

Query: 724 PSLKTPDGPVPGPGPQGAA------------PEPLG---ASVQRDSAQGRPCP------P 762
            S   PD  +  PGP  A             P P G   A+ +     G+P P      P
Sbjct: 418 TSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP 477

Query: 763 PQAPANQPEGASSAAPGS---------PVPA--PPTKASALPV------EQGPAEPIPPG 805
             AP   P+   +A P           P PA  P  +  +           GP E +P  
Sbjct: 478 QSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAV 537

Query: 806 VASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPE 865
            +S G  P        ++G   P   P      +P   P G  + P       SP   P 
Sbjct: 538 RSSQGGSPALF----TYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESP- 592

Query: 866 RPRPADRRLCLPCVDASPLPGRTACPSLQEA 896
            P PA       C   SP+    A PS +E+
Sbjct: 593 LPSPATNTAGSTCSSLSPMSSSPANPSSEES 623



 Score = 31.2 bits (69), Expect = 9.3
 Identities = 48/186 (25%), Positives = 64/186 (34%), Gaps = 42/186 (22%)

Query: 725  SLKTPDGPV-PG-PGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPV 782
            +L+ P+    PG PGP      PLGAS+ R  A+G+     +AP          APG+  
Sbjct: 3546 ALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPL--VFSGKRRAPGARG 3603

Query: 783  PAPP--------------TKASALPVEQGPAEPIPPGVA--------SGGLRPDALGPTT 820
               P                +S +  E GP      G A        S   R  A  P+ 
Sbjct: 3604 RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSK 3663

Query: 821  AHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVD 880
            A   P HP K   S A          PG    G  +   P +   +P P+ +        
Sbjct: 3664 ALKFPVHPRKAVGSLA----------PGELARGTENGMKPATPKAKPGPSSQG------S 3707

Query: 881  ASPLPG 886
             SP PG
Sbjct: 3708 GSPRPG 3713


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 60/213 (28%), Positives = 77/213 (36%), Gaps = 20/213 (9%)

Query: 694 ALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPG--PGPQGAAPEPLGASVQ 751
           AL ++   +    R   G+         G  + + P GP     P PQG  P+P G   Q
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQP-GPGPQ 475

Query: 752 RDSAQGRPCPPPQAPANQPEGASSAAPGSPVP--------APPTKAS-ALPVEQGPAEPI 802
           R     +  PPPQ    Q         GSP+P        AP   AS A P  QG     
Sbjct: 476 RQGPPLQQRPPPQG--QQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533

Query: 803 PPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDS 862
            P VA G   P A  P  +    R    P  ++ T   G  P      P G +  Q P  
Sbjct: 534 RP-VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 863 VPERPRPADRRLCLPCVDASPLPGRTACPSLQE 895
            P  P    R+       A P+P RT  P+ Q+
Sbjct: 593 KPPGPAGPTRQ----ASQAGPVP-RTGPPTTQQ 620



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 63/262 (24%), Positives = 96/262 (36%), Gaps = 37/262 (14%)

Query: 633 PSPGFLPVNSDTGLVAV--------------PGPVPGQHPCGEEATQLPAAFTSEATHFK 678
           PSPG LP+   T                   P P PG    G    Q P     +  H  
Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ--HLS 494

Query: 679 PIVLAQNASVARDQPA---LAQEESEERGGQREGEGEEKLSLEAHAGSP-SLKTPDGPVP 734
            +     + + +  P+     Q+ + +     +G+G +   +    G+P + + P  P P
Sbjct: 495 GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSP 554

Query: 735 ----GPGPQG------AAPEPLGASVQRDSAQGRPCPPPQAPANQPEGAS-SAAPGSPVP 783
               GP PQ       + P P  AS      Q R  PP + P   P G +  A+   PVP
Sbjct: 555 QRQAGP-PQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG--PAGPTRQASQAGPVP 611

Query: 784 --APPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPG 841
              PPT     P   GPA    P +A    +      T A  GP H P+  +S++     
Sbjct: 612 RTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPH-PQLNKSQSLTNAF 670

Query: 842 QEPEGPGATPAGERDDQSPDSV 863
             PE     P+  +D+   +++
Sbjct: 671 NLPEPAPPRPSLSQDEVKAETI 692



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 46/184 (25%)

Query: 721 AGSPSLKTPDG----PVPGPGPQGAAP----EPLGASVQRDSAQGRPC--PPPQ------ 764
           AG P+ + P      P PGPGPQ   P     P     Q  S  G P   P PQ      
Sbjct: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512

Query: 765 ----------APANQPEGASS----AAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGG 810
                     AP  Q +G  S      PG+P  A P  + +   + GP +       SG 
Sbjct: 513 SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP 572

Query: 811 LRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGP-GATPAGERDDQSPDSVP---ER 866
             P A G             PP  +  + P Q+P GP G T    +    P + P   ++
Sbjct: 573 APPKASG------------APPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQ 620

Query: 867 PRPA 870
           PRP+
Sbjct: 621 PRPS 624



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 21/71 (29%), Positives = 27/71 (38%), Gaps = 4/71 (5%)

Query: 357 AQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADP---- 412
           A P  R      P+ Q G      +++  GP  P + G P      QGP + P  P    
Sbjct: 542 APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT 601

Query: 413 RDASGEAQTPR 423
           R AS     PR
Sbjct: 602 RQASQAGPVPR 612


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,393,301
Number of Sequences: 37866
Number of extensions: 4775171
Number of successful extensions: 48461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 312
Number of HSP's successfully gapped in prelim test: 1965
Number of HSP's that attempted gapping in prelim test: 25915
Number of HSP's gapped (non-prelim): 17412
length of query: 1749
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1633
effective length of database: 13,855,062
effective search space: 22625316246
effective search space used: 22625316246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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