Search of human proteins with 116235491

Search of human proteins with 116235491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116235491 POU domain, class 5, transcription factor 1
isoform 2 [Homo sapiens]
         (265 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116235491 POU domain, class 5, transcription factor 1 isoform...   544   e-155
gi|42560248 POU domain, class 5, transcription factor 1 isoform ...   458   e-129
gi|227430410 POU class 5 homeobox 1B [Homo sapiens]                   439   e-123
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap...   204   5e-53
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                      189   2e-48
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...   189   3e-48
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...   187   1e-47
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s...   186   2e-47
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                     170   1e-42
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap...   168   4e-42
gi|148664218 POU transcription factor [Homo sapiens]                  164   6e-41
gi|170650730 pituitary specific transcription factor 1 isoform b...   140   9e-34
gi|4505955 pituitary specific transcription factor 1 isoform alp...   140   9e-34
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]     129   2e-30
gi|4505965 POU class 4 homeobox 3 [Homo sapiens]                      125   3e-29
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...   125   4e-29
gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                    112   3e-25
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    86   4e-17
gi|30410785 LIM homeobox protein 1 [Homo sapiens]                      49   5e-06
gi|11641283 LIM homeobox protein 5 [Homo sapiens]                      48   8e-06
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    48   1e-05
gi|15375314 LIM homeobox protein 4 [Homo sapiens]                      47   1e-05
gi|7110735 ventral anterior homeobox 2 [Homo sapiens]                  47   2e-05
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            47   2e-05
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             47   2e-05
gi|61969666 arginine-fifty homeobox [Homo sapiens]                     47   2e-05
gi|11386181 H2.0-like homeobox [Homo sapiens]                          45   5e-05
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  45   9e-05
gi|24497589 aristaless related homeobox [Homo sapiens]                 44   1e-04
gi|7706659 paired related homeobox 2 [Homo sapiens]                    44   1e-04

>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
           [Homo sapiens]
          Length = 265

 Score =  544 bits (1401), Expect = e-155
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 1   MHFYRLFLGATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLLKQ 60
           MHFYRLFLGATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLLKQ
Sbjct: 1   MHFYRLFLGATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLLKQ 60

Query: 61  KRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNE 120
           KRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNE
Sbjct: 61  KRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNE 120

Query: 121 NLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVR 180
           NLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVR
Sbjct: 121 NLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVR 180

Query: 181 VWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYS 240
           VWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYS
Sbjct: 181 VWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYS 240

Query: 241 SVPFPEGEAFPPVSVTTLGSPMHSN 265
           SVPFPEGEAFPPVSVTTLGSPMHSN
Sbjct: 241 SVPFPEGEAFPPVSVTTLGSPMHSN 265


>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
           [Homo sapiens]
          Length = 360

 Score =  458 bits (1179), Expect = e-129
 Identities = 225/226 (99%), Positives = 226/226 (100%)

Query: 40  QSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF 99
           +SQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF
Sbjct: 135 ESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF 194

Query: 100 KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 159
           KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK
Sbjct: 195 KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 254

Query: 160 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 219
           PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL
Sbjct: 255 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 314

Query: 220 APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 265
           APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Sbjct: 315 APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 360


>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
          Length = 359

 Score =  439 bits (1129), Expect = e-123
 Identities = 218/226 (96%), Positives = 220/226 (97%), Gaps = 1/226 (0%)

Query: 40  QSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF 99
           +SQDIKALQKELEQFAKLLKQKRITLGYTQADVGL LGVLFGKVFSQ TICRFEALQLSF
Sbjct: 135 KSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSF 194

Query: 100 KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 159
           KNMCKLRPLLQKWVEEADNNENLQEICKAETL+QARKRKRTSIENRVRGNLENLFLQCPK
Sbjct: 195 KNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPK 254

Query: 160 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 219
           PTL QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFP 
Sbjct: 255 PTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPP 313

Query: 220 APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 265
           APGPHFGTPGYGSPHFTALYSSVPFPEGE FPPVSV TLGSPMHSN
Sbjct: 314 APGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN 359


>gi|23463326 POU domain class 5, transcription factor 2 [Homo
           sapiens]
          Length = 328

 Score =  204 bits (520), Expect = 5e-53
 Identities = 118/232 (50%), Positives = 148/232 (63%), Gaps = 12/232 (5%)

Query: 29  YVLTSLLPFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTT 88
           Y+    +P     +DI  + KEL+Q AK L+QKR++LGY+QADVG+ +G LFGKV SQTT
Sbjct: 104 YIALRSIPKLPPPEDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTT 163

Query: 89  ICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQ-ARKRKRTSIENRVR 147
           ICRFEA QLS  NM KLRPLL+KW++E +  ENL  +CK E ++Q + K +R S E R+ 
Sbjct: 164 ICRFEAQQLSVANMWKLRPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRASRERRIG 222

Query: 148 GNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAG 207
            +LE  F +CPKPT QQISHIA  L L+KDVVRVWF NR + G R ++D + RE    AG
Sbjct: 223 NSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAG 282

Query: 208 SPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLG 259
            P  G PV F L      G P    PH+T LYS+     G A      TTLG
Sbjct: 283 PPCPGAPVCFHLG----LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLG 324


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score =  189 bits (481), Expect = 2e-48
 Identities = 101/177 (57%), Positives = 125/177 (70%), Gaps = 3/177 (1%)

Query: 50  ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 109
           +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFEALQLSFKNMCKL+PLL
Sbjct: 321 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 380

Query: 110 QKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIA 169
            KW+EEAD++               +++KRTSIE  V+G LE+ FL+CPKP+ Q+I+++A
Sbjct: 381 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLA 440

Query: 170 QQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFG 226
             L LEK+VVRVWFCNRRQK KR +    Q++  +   S    G VS    P PH G
Sbjct: 441 DSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQV--GTVSAD-TPPPHHG 494


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score =  189 bits (479), Expect = 3e-48
 Identities = 107/184 (58%), Positives = 128/184 (69%), Gaps = 15/184 (8%)

Query: 50  ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 109
           +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFEALQLSFKNMCKL+PLL
Sbjct: 254 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 313

Query: 110 QKWVEEADNNE----NLQEICKAETLVQARKR-KRTSIENRVRGNLENLFLQCPKPTLQQ 164
            KW+EE D++     NL +I       Q RKR KRTSIE  V+G LE+ FL+CPKP+  +
Sbjct: 314 NKWLEETDSSSGSPTNLDKIA-----AQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHE 368

Query: 165 ISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFEAAGS-PFSGGPVSFPL 219
           I+ +A  L LEK+VVRVWFCNRRQK KR    + + +   +D  A G     GG  S P 
Sbjct: 369 ITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPS 428

Query: 220 APGP 223
           AP P
Sbjct: 429 APPP 432


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score =  187 bits (474), Expect = 1e-47
 Identities = 92/143 (64%), Positives = 111/143 (77%)

Query: 50  ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 109
           +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFEALQLSFKNMCKL+PLL
Sbjct: 269 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 328

Query: 110 QKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIA 169
            KW+EEAD++               +++KRTSIE  V+G LE+ FL+CPKP+ Q+I+ +A
Sbjct: 329 NKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLA 388

Query: 170 QQLGLEKDVVRVWFCNRRQKGKR 192
             L LEK+VVRVWFCNRRQK KR
Sbjct: 389 DSLQLEKEVVRVWFCNRRQKEKR 411


>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
           sapiens]
          Length = 361

 Score =  186 bits (472), Expect = 2e-47
 Identities = 93/143 (65%), Positives = 108/143 (75%)

Query: 50  ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 109
           ELEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFE LQLSFKNMCKL+PLL
Sbjct: 193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEGLQLSFKNMCKLKPLL 252

Query: 110 QKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIA 169
            KW+EEAD++               +++KRTSIE  V+G LE  FL+CPKP  Q+IS +A
Sbjct: 253 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLA 312

Query: 170 QQLGLEKDVVRVWFCNRRQKGKR 192
             L LEK+VVRVWFCNRRQK KR
Sbjct: 313 DSLQLEKEVVRVWFCNRRQKEKR 335


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score =  170 bits (430), Expect = 1e-42
 Identities = 91/178 (51%), Positives = 115/178 (64%), Gaps = 20/178 (11%)

Query: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL 108
           +ELEQFAK  KQ+RI LG+TQ DVGL +G L+G  FSQTTI RFEAL LSFKNMCKL+PL
Sbjct: 286 EELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPL 345

Query: 109 LQKWVEEADNNENLQEICKAETL-------VQARKRKRTSIENRVRGNLENLFLQCPKPT 161
           L+KW+ +A+N  +   +     L       +  R++KRTSIE  +R  LE  FL+  KPT
Sbjct: 346 LEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPT 405

Query: 162 LQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 219
            ++I+ IA QL +EK+V+RVWFCNRRQK KR                P SGG  S P+
Sbjct: 406 SEEITMIADQLNMEKEVIRVWFCNRRQKEKR-------------INPPSSGGTSSSPI 450


>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
           sapiens]
          Length = 463

 Score =  168 bits (426), Expect = 4e-42
 Identities = 102/222 (45%), Positives = 131/222 (59%), Gaps = 27/222 (12%)

Query: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL 108
           +ELEQFA+  KQ+RI LG+TQ DVGL +G L+G  FSQTTI RFEAL LSFKNMCKL+PL
Sbjct: 185 EELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPL 244

Query: 109 LQKWVEEADN----------NENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCP 158
           L+KW+ +A+           N+        + L   R++KRTSIE  VR  LE  FL   
Sbjct: 245 LEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQ 304

Query: 159 KPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFP 218
           KPT ++I  IA+QL +EK+V+RVWFCNRRQK KR +   A      A   P  G P S+ 
Sbjct: 305 KPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSA------APMLPSPGKPASY- 357

Query: 219 LAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGS 260
               PH  TP  G+        ++P  +  +    +VTTL S
Sbjct: 358 ---SPHMVTPQGGA-------GTLPLSQASSSLSTTVTTLSS 389


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score =  164 bits (416), Expect = 6e-41
 Identities = 86/150 (57%), Positives = 109/150 (72%), Gaps = 6/150 (4%)

Query: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL 108
           +ELE+FAK  KQ+RI LG+TQ DVGL +G L+G  FSQTTI RFEAL LSFKNMCKL+PL
Sbjct: 189 EELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPL 248

Query: 109 LQKWVEEADNNENLQEICKAETL-----VQARKR-KRTSIENRVRGNLENLFLQCPKPTL 162
           L+KW+ +A+++ +   +    +      V  RKR KRTSIE  +R  LE  F   PKP+ 
Sbjct: 249 LEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSS 308

Query: 163 QQISHIAQQLGLEKDVVRVWFCNRRQKGKR 192
           ++IS IA+QL +EK+VVRVWFCNRRQK KR
Sbjct: 309 EEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338


>gi|170650730 pituitary specific transcription factor 1 isoform beta
           [Homo sapiens]
          Length = 317

 Score =  140 bits (354), Expect = 9e-34
 Identities = 80/165 (48%), Positives = 104/165 (63%), Gaps = 8/165 (4%)

Query: 36  PFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEAL 95
           P  + S +I+    ELE+FA   K +RI LGYTQ +VG  L  + G  FSQTTICRFE L
Sbjct: 147 PIDMDSPEIR----ELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENL 202

Query: 96  QLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGNLENLF 154
           QLSFKN CKL+ +L KW+EEA   E +  +   +     RKRK RT+I    +  LE  F
Sbjct: 203 QLSFKNACKLKAILSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDALERHF 259

Query: 155 LQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 199
            +  KP+ Q+I  +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 260 GEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 304


>gi|4505955 pituitary specific transcription factor 1 isoform alpha
           [Homo sapiens]
          Length = 291

 Score =  140 bits (354), Expect = 9e-34
 Identities = 80/165 (48%), Positives = 104/165 (63%), Gaps = 8/165 (4%)

Query: 36  PFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEAL 95
           P  + S +I+    ELE+FA   K +RI LGYTQ +VG  L  + G  FSQTTICRFE L
Sbjct: 121 PIDMDSPEIR----ELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENL 176

Query: 96  QLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGNLENLF 154
           QLSFKN CKL+ +L KW+EEA   E +  +   +     RKRK RT+I    +  LE  F
Sbjct: 177 QLSFKNACKLKAILSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDALERHF 233

Query: 155 LQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 199
            +  KP+ Q+I  +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 234 GEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 278


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score =  129 bits (325), Expect = 2e-30
 Identities = 76/156 (48%), Positives = 105/156 (67%), Gaps = 9/156 (5%)

Query: 43  DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKV-----FSQTTICRFEALQL 97
           D+ A  ++LE FA+  KQ+RI LG TQADVG  L  L  K+      SQ+TICRFE+L L
Sbjct: 250 DVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANL--KIPGVGSLSQSTICRFESLTL 307

Query: 98  SFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQA-RKRKRTSIENRVRGNLENLFLQ 156
           S  NM  L+P+LQ W+EEA+ +   +++ K E    A +KRKRTSI    + +LE  F  
Sbjct: 308 SHNNMIALKPILQAWLEEAEKSHR-EKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAI 366

Query: 157 CPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 192
            P+P+ ++I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 367 QPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 402


>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
          Length = 338

 Score =  125 bits (315), Expect = 3e-29
 Identities = 74/155 (47%), Positives = 100/155 (64%), Gaps = 7/155 (4%)

Query: 43  DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKV-----FSQTTICRFEALQL 97
           D+++  +ELE FA+  KQ+RI LG TQADVG  L  L  K+      SQ+TICRFE+L L
Sbjct: 179 DVESDPRELEAFAERFKQRRIKLGVTQADVGAALANL--KIPGVGSLSQSTICRFESLTL 236

Query: 98  SFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQC 157
           S  NM  L+P+LQ W+EEA+     +           RKRKRTSI    + +LE  F   
Sbjct: 237 SHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQ 296

Query: 158 PKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 192
           P+P+ ++I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 297 PRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score =  125 bits (314), Expect = 4e-29
 Identities = 74/150 (49%), Positives = 101/150 (67%), Gaps = 9/150 (6%)

Query: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKV-----FSQTTICRFEALQLSFKNMC 103
           +ELE FA+  KQ+RI LG TQADVG  L  L  K+      SQ+TICRFE+L LS  NM 
Sbjct: 266 RELEAFAERFKQRRIKLGVTQADVGSALANL--KIPGVGSLSQSTICRFESLTLSHNNMI 323

Query: 104 KLRPLLQKWVEEADNNENLQEICKAETLVQA-RKRKRTSIENRVRGNLENLFLQCPKPTL 162
            L+P+LQ W+EEA+  +  +++ K E      +KRKRTSI    + +LE  F   P+P+ 
Sbjct: 324 ALKPILQAWLEEAEGAQR-EKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSS 382

Query: 163 QQISHIAQQLGLEKDVVRVWFCNRRQKGKR 192
           ++I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 383 EKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 412


>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score =  112 bits (280), Expect = 3e-25
 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 7/151 (4%)

Query: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL 108
           +E+ +FAK  K +R++LG TQ  VG  L    G  +SQ+ ICRFE L ++ K+  KL+P+
Sbjct: 145 EEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPV 204

Query: 109 LQKWVEEA-----DNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQ 163
           L+KW+ EA     +  +NL E    E     ++++RTS   +    L   F + P PT Q
Sbjct: 205 LEKWLNEAELRNQEGQQNLMEFVGGEP--SKKRKRRTSFTPQAIEALNAYFEKNPLPTGQ 262

Query: 164 QISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 194
           +I+ IA++L  +++VVRVWFCNRRQ  K +S
Sbjct: 263 EITEIAKELNYDREVVRVWFCNRRQTLKNTS 293


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 56/194 (28%), Positives = 93/194 (47%), Gaps = 43/194 (22%)

Query: 49  KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICR----------------- 91
           +E+ +FAK  K +R++LG TQ  VG  L    G  +SQ+ ICR                 
Sbjct: 482 EEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQEN 541

Query: 92  -------------------FEALQLSFKNMCKLRPLLQKWVEEADNN-----ENLQEICK 127
                              FE L ++ K+  K++P+L++W+ EA+       +NL E   
Sbjct: 542 TIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIG 601

Query: 128 AETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRR 187
           +E     ++++RTS   +    L   F +   P+ Q+++ IA++L  +++VVRVWFCN+R
Sbjct: 602 SEP--SKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKR 659

Query: 188 QKGKRSSSDYAQRE 201
           Q  K +     Q E
Sbjct: 660 QALKNTIKRLKQHE 673


>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
          Length = 406

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)

Query: 114 EEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLG 173
           +EA +NEN       + L   R+  RT+I+ +    L+  F   PKPT      +AQ+ G
Sbjct: 164 KEAGSNEN-----DDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 218

Query: 174 LEKDVVRVWFCNRRQKGKR 192
           L   V++VWF NRR K +R
Sbjct: 219 LNMRVIQVWFQNRRSKERR 237


>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
          Length = 402

 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 5/79 (6%)

Query: 114 EEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLG 173
           +E  NNEN ++    +     R+  RT+I+ +    L+  F   PKPT      +AQ+ G
Sbjct: 164 KETANNENEEQNSGTK-----RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 218

Query: 174 LEKDVVRVWFCNRRQKGKR 192
           L   V++VWF NRR K +R
Sbjct: 219 LNMRVIQVWFQNRRSKERR 237


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 23/115 (20%)

Query: 150 LENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSP 209
           LE  F Q    +  +  H+A  L L    V++WF NRR K KR   D    +  E AG P
Sbjct: 65  LERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQD----KSLELAGHP 120

Query: 210 FSGGPVSFP---------LAPGPHFGTPGYGSPHFTAL--------YSSVPFPEG 247
            +   V+ P         L PGP  G P + SP+  A+        YS  P+  G
Sbjct: 121 LTPRRVAVPVLVRDGKPCLGPGP--GAPAFPSPYSAAVSPYSCYGGYSGAPYGAG 173


>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
          Length = 390

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 24/61 (39%), Positives = 33/61 (54%)

Query: 136 KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 195
           KR RT+I  +    L+N +   PKP       ++ + GL+  VV+VWF NRR K KR   
Sbjct: 158 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217

Query: 196 D 196
           D
Sbjct: 218 D 218


>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
          Length = 290

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 8/131 (6%)

Query: 136 KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 195
           KR RTS        LE  F +C     ++ + +A+QL L +  V+VWF NRR K K+  S
Sbjct: 103 KRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQS 162

Query: 196 DYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVP-FPEGEAFPPVS 254
              ++    +A   F+   +   L  G     P   +P   AL  S+P  P         
Sbjct: 163 RDLEKRASSSASEAFATSNILRLLEQGRLLSVP--RAPSLLALTPSLPGLPASH-----R 215

Query: 255 VTTLGSPMHSN 265
            T+LG P +S+
Sbjct: 216 GTSLGDPRNSS 226


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 120 ENLQEICKA--ETLVQAR-----KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQL 172
           E+ + +CKA  ET  Q       KR RT+I  +    L++ +   PKP       ++ + 
Sbjct: 135 EDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSET 194

Query: 173 GLEKDVVRVWFCNRRQKGKRSSSD 196
           GL+  VV+VWF NRR K KR   D
Sbjct: 195 GLDMRVVQVWFQNRRAKEKRLKKD 218


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 120 ENLQEICKA--ETLVQAR-----KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQL 172
           E+ + +CKA  ET  Q       KR RT+I  +    L++ +   PKP       ++ + 
Sbjct: 140 EDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSET 199

Query: 173 GLEKDVVRVWFCNRRQKGKRSSSD 196
           GL+  VV+VWF NRR K KR   D
Sbjct: 200 GLDMRVVQVWFQNRRAKEKRLKKD 223


>gi|61969666 arginine-fifty homeobox [Homo sapiens]
          Length = 315

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 6/116 (5%)

Query: 128 AETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRR 187
           A T ++ R ++RTS  ++    LE LF Q   P       +A +L L +  V+VWF NRR
Sbjct: 71  ATTAIRRRHKERTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRR 130

Query: 188 QKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVP 243
            K K+     + ++  +   S     P S   +P P+       SP  +  YSS+P
Sbjct: 131 FKLKKQQQQQSAKQRNQILPSK-KNVPTSPRTSPSPY-----AFSPVISDFYSSLP 180


>gi|11386181 H2.0-like homeobox [Homo sapiens]
          Length = 488

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 129 ETLVQARKRKRT----SIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFC 184
           +T+ Q  KRKR+       N  R  LE  F      T      +A  LGL    V+VWF 
Sbjct: 266 DTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQ 325

Query: 185 NRRQKGKRSSSDYAQREDFEAAGSPFSGG 213
           NRR K + S    AQ++  + AG   SGG
Sbjct: 326 NRRMKWRHSKEAQAQKDKDKEAGEKPSGG 354


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 28/85 (32%), Positives = 46/85 (54%)

Query: 108  LLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISH 167
            L +K  ++ DNN + +E   +       KR RT+I       L   +L    PT + + H
Sbjct: 2533 LKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDH 2592

Query: 168  IAQQLGLEKDVVRVWFCNRRQKGKR 192
            IA+++GL+K VV+VWF N R + ++
Sbjct: 2593 IAREVGLKKRVVQVWFQNTRARERK 2617



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 22/57 (38%), Positives = 31/57 (54%)

Query: 136  KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 192
            KR RT + N     L+  F     PT+Q+   +  ++GL K VV+VWF N R K K+
Sbjct: 2885 KRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKK 2941



 Score = 34.7 bits (78), Expect = 0.088
 Identities = 20/71 (28%), Positives = 35/71 (49%)

Query: 134  ARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRS 193
            +++  RT   +     L++ F     P   +I  ++  L L   V+ VWF N RQK ++S
Sbjct: 2180 SKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKS 2239

Query: 194  SSDYAQREDFE 204
              + A+ +D E
Sbjct: 2240 YENQAETKDNE 2250



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 19/61 (31%), Positives = 31/61 (50%)

Query: 136  KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 195
            KR RT I +     L   F     P+ +QI  +A++ GL + V++ WF N   K ++ + 
Sbjct: 2085 KRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNK 2144

Query: 196  D 196
            D
Sbjct: 2145 D 2145


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 32/188 (17%)

Query: 93  EALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKA------ETLVQARKRK-RTSIENR 145
           E  +LS K    L P      E+A+  +    +C +      E L++ ++R+ RT+  + 
Sbjct: 285 EGGELSPKEELLLHP------EDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSY 338

Query: 146 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 205
               LE  F +   P +     +A +L L +  V+VWF NRR K ++     AQ      
Sbjct: 339 QLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQT---HP 395

Query: 206 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTAL--------------YSSVPFPEGEAFP 251
            G PF  GP+S      P+     +  PH  AL              + S+P P G A  
Sbjct: 396 PGLPFP-GPLSATHPLSPYLDASPF-PPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASL 453

Query: 252 PVSVTTLG 259
           P S   LG
Sbjct: 454 PPSGAPLG 461


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/124 (28%), Positives = 53/124 (42%), Gaps = 6/124 (4%)

Query: 126 CKAETLVQARKRKRTSIENRVRGN------LENLFLQCPKPTLQQISHIAQQLGLEKDVV 179
           C +     A KRK+    NR   N      LE +F +   P       +A+++ L +  V
Sbjct: 89  CPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARV 148

Query: 180 RVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALY 239
           +VWF NRR K +R+              S      +  P+AP P   +P Y S   ++ Y
Sbjct: 149 QVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPY 208

Query: 240 SSVP 243
           S+VP
Sbjct: 209 STVP 212


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,976,203
Number of Sequences: 37866
Number of extensions: 563195
Number of successful extensions: 2296
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 1966
Number of HSP's gapped (non-prelim): 390
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.