Guide to the Human Genome
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Search of human proteins with 239582749

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239582749 sterile alpha motif domain containing 4 isoform 2
[Homo sapiens]
         (629 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239582749 sterile alpha motif domain containing 4 isoform 2 [...  1268   0.0  
gi|239582747 sterile alpha motif domain containing 4 isoform 1 [...   783   0.0  
gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens]   617   e-177
gi|239582751 sterile alpha motif domain containing 4 isoform 3 [...   606   e-173
gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens]      54   4e-07
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            38   0.032
gi|66392146 RNA U, small nuclear RNA export adaptor (phosphoryla...    37   0.055
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    36   0.094
gi|169234659 tumor protein p63 isoform 3 [Homo sapiens]                35   0.16 
gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]                35   0.16 
gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]                 35   0.16 
gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]                35   0.27 
gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]                35   0.27 
gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]                35   0.27 
gi|209862789 microtubule associated monoxygenase, calponin and L...    35   0.27 
gi|98961156 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|98961154 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|98961152 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|98961150 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|98961148 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|98961143 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|98961146 tetratricopeptide repeat domain 23 [Homo sapiens]          34   0.47 
gi|154090979 hypothetical protein LOC57481 [Homo sapiens]              34   0.47 
gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]    33   0.61 
gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]    33   0.61 
gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Ho...    33   0.79 
gi|188536004 zinc finger protein 469 [Homo sapiens]                    33   0.79 
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         33   1.0  
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    33   1.0  
gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo sapi...    32   1.4  

>gi|239582749 sterile alpha motif domain containing 4 isoform 2
           [Homo sapiens]
          Length = 629

 Score = 1268 bits (3280), Expect = 0.0
 Identities = 629/629 (100%), Positives = 629/629 (100%)

Query: 1   MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60
           MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE
Sbjct: 1   MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60

Query: 61  ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE 120
           ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE
Sbjct: 61  ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE 120

Query: 121 SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ 180
           SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ
Sbjct: 121 SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ 180

Query: 181 NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTNVP 240
           NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTNVP
Sbjct: 181 NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTNVP 240

Query: 241 AWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKS 300
           AWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKS
Sbjct: 241 AWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKS 300

Query: 301 LERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPD 360
           LERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPD
Sbjct: 301 LERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPD 360

Query: 361 CKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLL 420
           CKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLL
Sbjct: 361 CKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLL 420

Query: 421 VSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQ 480
           VSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQ
Sbjct: 421 VSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQ 480

Query: 481 QRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTA 540
           QRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTA
Sbjct: 481 QRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTA 540

Query: 541 TPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVTE 600
           TPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVTE
Sbjct: 541 TPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVTE 600

Query: 601 PDINNRLESLCLSMTEHALGDGVDRTSTI 629
           PDINNRLESLCLSMTEHALGDGVDRTSTI
Sbjct: 601 PDINNRLESLCLSMTEHALGDGVDRTSTI 629


>gi|239582747 sterile alpha motif domain containing 4 isoform 1
           [Homo sapiens]
          Length = 717

 Score =  783 bits (2021), Expect = 0.0
 Identities = 391/392 (99%), Positives = 392/392 (100%)

Query: 238 NVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNL 297
           +VPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNL
Sbjct: 326 DVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNL 385

Query: 298 LKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQ 357
           LKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQ
Sbjct: 386 LKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQ 445

Query: 358 SPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCT 417
           SPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCT
Sbjct: 446 SPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCT 505

Query: 418 QLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISG 477
           QLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISG
Sbjct: 506 QLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISG 565

Query: 478 YRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRN 537
           YRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRN
Sbjct: 566 YRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRN 625

Query: 538 TTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLP 597
           TTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLP
Sbjct: 626 TTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLP 685

Query: 598 VTEPDINNRLESLCLSMTEHALGDGVDRTSTI 629
           VTEPDINNRLESLCLSMTEHALGDGVDRTSTI
Sbjct: 686 VTEPDINNRLESLCLSMTEHALGDGVDRTSTI 717



 Score =  487 bits (1254), Expect = e-137
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60
           MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE
Sbjct: 1   MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60

Query: 61  ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE 120
           ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE
Sbjct: 61  ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE 120

Query: 121 SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ 180
           SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ
Sbjct: 121 SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ 180

Query: 181 NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTST 237
           NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTST
Sbjct: 181 NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTST 237


>gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens]
          Length = 694

 Score =  617 bits (1592), Expect = e-177
 Identities = 359/709 (50%), Positives = 443/709 (62%), Gaps = 96/709 (13%)

Query: 1   MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60
           MFRDQVG+LAGWFKGWNECEQTVALLSLLKRV++TQARFLQLCLEHSLADC ++H+LE E
Sbjct: 2   MFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESE 61

Query: 61  ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKIL------------ 108
           ANS  I++QWQQESK+KV+SLLL+HLPLL+PGN +AK EYM+LL K+L            
Sbjct: 62  ANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEE 121

Query: 109 -----AHSIEHNQHIEESRQLLSYALIH------------PATSLEDRSALAMWLNHLED 151
                ++++ H     E R  L+  L H            P  S   R     W    E 
Sbjct: 122 SRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAE- 180

Query: 152 RTSTSFGGQNRGRSDSVDYGQTHY-YHQRQNSDDKLNGWQNSRDSGICINA--------- 201
                 G    G  D       H  +H   +    +N   ++ ++G+             
Sbjct: 181 ---LGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSM 237

Query: 202 ----------SNWQD-KSMGCENG-----HVPLYSSSSVPTT----INTIGTSTST---- 237
                       W   + +G         H PL   SSV ++        G+S +T    
Sbjct: 238 SLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQED 297

Query: 238 -----NVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLK 292
                +VP+WLKSLRLHKYAALFSQM+YEEMM LTE  LE+QNVTKGARHKI +SIQKL+
Sbjct: 298 GSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLR 357

Query: 293 ERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYS-------SPSTTPEARRREPQA 345
           ERQ++LKSLE+D++EGG+LR  LQEL Q+I+TPIKAYS       + +TTP A+   P  
Sbjct: 358 ERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGE 417

Query: 346 PRQPSLMGP-----ESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLP 400
           P  P    P       +  + KD  A       P+   + G +P          A AP+ 
Sbjct: 418 PPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEP----------APAPVA 467

Query: 401 EGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQV 460
           +GD+P QFTRVMGKVCTQLLVSRPDEENI+SYLQLI+KCL HEAFTETQKKRLLSWKQQV
Sbjct: 468 DGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQV 527

Query: 461 QKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSA 520
            KL R+FPRK  L++  YRQQ+   FG SNSLP AGSVG G+ RR  RQ+ +P R +P  
Sbjct: 528 LKLLRTFPRKAALEMQNYRQQKGWAFG-SNSLPIAGSVGMGVARRTQRQFPMPPRALPPG 586

Query: 521 RLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVH 580
           R+GLL  SG    + R+   +P++  QGRQNLWFANPGGSNSMPS++ SSVQRT SLPVH
Sbjct: 587 RMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVH 646

Query: 581 TSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI 629
           +SPQ +LMF  P+  +P  + +IN  LESLCLSMTEHALGDG D+TSTI
Sbjct: 647 SSPQAILMF-PPDCPVPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI 694


>gi|239582751 sterile alpha motif domain containing 4 isoform 3
           [Homo sapiens]
          Length = 345

 Score =  606 bits (1562), Expect = e-173
 Identities = 309/345 (89%), Positives = 309/345 (89%), Gaps = 36/345 (10%)

Query: 321 MILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASG 380
           MILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASG
Sbjct: 1   MILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASG 60

Query: 381 GLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCL 440
           GLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCL
Sbjct: 61  GLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCL 120

Query: 441 IHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGG 500
           IHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGG
Sbjct: 121 IHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGG 180

Query: 501 GMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGS 560
           GMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGS
Sbjct: 181 GMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGS 240

Query: 561 NSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQP---------------------------- 592
           NSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQP                            
Sbjct: 241 NSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPGSQVHSGLCLTDLRGWLSLSGAPSMPAL 300

Query: 593 --------EFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI 629
                   EFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI
Sbjct: 301 TVPKSSQGEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI 345


>gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens]
          Length = 949

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 73/288 (25%), Positives = 119/288 (41%), Gaps = 23/288 (7%)

Query: 224 VPTTINTIGTSTSTNVPAWLKSLRLHKYAALFSQMTYEEMMALTECQL-EAQNVTKGARH 282
           +P+++ T  T     +  WL+ LRLHKY  +F Q++ E+ ++LTE  L + +++T GA+ 
Sbjct: 286 MPSSLQTPQTQEQNGILDWLRKLRLHKYYPVFKQLSMEKFLSLTEEDLNKFESLTMGAKK 345

Query: 283 KIVISIQKLK---ERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEAR 339
           K+   ++  K   ER+ L  S    +   G  R+P    H   +   +   +     E  
Sbjct: 346 KLKTQLELEKEKSERRCLNPSAPPLVTSSGVARVP-PTSHVGPVQSGRGSHAAELRVEVE 404

Query: 340 RREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPL 399
           +   Q PR+ S     S S     G  A   ++  +      ++ H L S D E  V   
Sbjct: 405 QPHHQLPREGS-SSEYSSSSSSPMGVQAREESSDSAEENDRRVEIH-LESSDKEKPVM-- 460

Query: 400 PEGDLPGQFTRVMGKVCTQLL-VSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQ 458
               L   FT    +   Q+L V      N S +  L  + L   A +     R+L+   
Sbjct: 461 ----LLNHFTSSSARPTAQVLPVQNEASSNPSGHHPLPPQML--SAASHITPIRMLN--- 511

Query: 459 QVQKLFRSFPRKTLLDISGYR----QQRNRGFGQSNSLPTAGSVGGGM 502
            V K  R      LL  S +     ++RN+G G  +S+    S G  M
Sbjct: 512 SVHKPERGSADMKLLSSSVHSLLSLEERNKGSGPRSSMKVDKSFGSAM 559


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 37.7 bits (86), Expect = 0.032
 Identities = 21/64 (32%), Positives = 26/64 (40%)

Query: 332 PSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCD 391
           P    E R R P+ PR+    G E +SPD      A+   A P A  S  L     +   
Sbjct: 367 PGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGS 426

Query: 392 GELA 395
           GE A
Sbjct: 427 GEAA 430



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 332 PSTTPEARRREPQAPRQPSLMGPESQSPDCKDGA--AATGATATPSAGASG 380
           P   PE      + P +P   G E++ P+  +GA  A  GA A   AG  G
Sbjct: 14  PQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGG 64


>gi|66392146 RNA U, small nuclear RNA export adaptor
           (phosphorylation regulated) [Homo sapiens]
          Length = 394

 Score = 37.0 bits (84), Expect = 0.055
 Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 22/175 (12%)

Query: 380 GGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDE--ENISSYLQLID 437
           G ++  QLS  D ++ VAP    D P Q  +V+G                 +S Y  +  
Sbjct: 6   GDMEDGQLSDSDSDMTVAP---SDRPLQLPKVLGGDSAMRAFQNTATACAPVSHYRAVES 62

Query: 438 KCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGS 497
                E+F+++     L WK++ QK F   P+                FGQS+  P    
Sbjct: 63  VDSSEESFSDSDDDSCL-WKRKRQKCFNPPPKPEPFQ-----------FGQSSQKP---P 107

Query: 498 VGGGMGRRN--PRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQ 550
           V GG    N      Q  +++  +  LG+LG  G +  ++++ T    + K+ R+
Sbjct: 108 VAGGKKINNIWGAVLQEQNQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLRK 162


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 36.2 bits (82), Expect = 0.094
 Identities = 34/123 (27%), Positives = 42/123 (34%), Gaps = 20/123 (16%)

Query: 308 GGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMG-----PESQSPDCK 362
           GG L+ P         TP+ + +    +     R P  P QP   G     P   +P  K
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281

Query: 363 DGAAATG-------ATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKV 415
           D A A G       AT +PSA  S    P         L   P P    P Q T  +G  
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPP--------SLQTLPSPPATPPSQATTSLGSP 333

Query: 416 CTQ 418
             Q
Sbjct: 334 TLQ 336



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 12/95 (12%)

Query: 325 PIKA-YSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGL- 382
           P++A +S P++ P +    P +   PSL  P  Q P     +     +ATP   A   L 
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467

Query: 383 -QPHQLSS---------CDGELAVAPLPEGDLPGQ 407
             P QL+              L   P P    PGQ
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 10/75 (13%)

Query: 315 LQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATP 374
           LQ  H  + +P     SP  TP      PQAP  P+L  P  Q+P     +      ATP
Sbjct: 335 LQATHSFLPSPPL---SPLATPP-----PQAP--PALALPPLQAPPSPPASPPLSPLATP 384

Query: 375 SAGASGGLQPHQLSS 389
           S  A   L  H L +
Sbjct: 385 SPQAPNALAVHLLQA 399


>gi|169234659 tumor protein p63 isoform 3 [Homo sapiens]
          Length = 487

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 15/112 (13%)

Query: 279 GARHKIVISIQKLKERQN--------------LLKSLERDIIEGGSLRIPLQELH-QMIL 323
           GA +KI IS+  ++ + +              LL S+++ I  G S   P    H Q  +
Sbjct: 84  GATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSV 143

Query: 324 TPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPS 375
           T    Y+ PS+T +A    P  P      GP S     +  + A  AT T S
Sbjct: 144 TAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYS 195


>gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]
          Length = 555

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 15/112 (13%)

Query: 279 GARHKIVISIQKLKERQN--------------LLKSLERDIIEGGSLRIPLQELH-QMIL 323
           GA +KI IS+  ++ + +              LL S+++ I  G S   P    H Q  +
Sbjct: 84  GATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSV 143

Query: 324 TPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPS 375
           T    Y+ PS+T +A    P  P      GP S     +  + A  AT T S
Sbjct: 144 TAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYS 195


>gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]
          Length = 680

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 15/112 (13%)

Query: 279 GARHKIVISIQKLKERQN--------------LLKSLERDIIEGGSLRIPLQELH-QMIL 323
           GA +KI IS+  ++ + +              LL S+++ I  G S   P    H Q  +
Sbjct: 84  GATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSV 143

Query: 324 TPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPS 375
           T    Y+ PS+T +A    P  P      GP S     +  + A  AT T S
Sbjct: 144 TAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYS 195


>gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]
          Length = 393

 Score = 34.7 bits (78), Expect = 0.27
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 297 LLKSLERDIIEGGSLRIPLQELH-QMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPE 355
           LL S+++ I  G S   P    H Q  +T    Y+ PS+T +A    P  P      GP 
Sbjct: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81

Query: 356 SQSPDCKDGAAATGATATPS 375
           S     +  + A  AT T S
Sbjct: 82  SFDVSFQQSSTAKSATWTYS 101


>gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]
          Length = 461

 Score = 34.7 bits (78), Expect = 0.27
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 297 LLKSLERDIIEGGSLRIPLQELH-QMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPE 355
           LL S+++ I  G S   P    H Q  +T    Y+ PS+T +A    P  P      GP 
Sbjct: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81

Query: 356 SQSPDCKDGAAATGATATPS 375
           S     +  + A  AT T S
Sbjct: 82  SFDVSFQQSSTAKSATWTYS 101


>gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]
          Length = 586

 Score = 34.7 bits (78), Expect = 0.27
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 297 LLKSLERDIIEGGSLRIPLQELH-QMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPE 355
           LL S+++ I  G S   P    H Q  +T    Y+ PS+T +A    P  P      GP 
Sbjct: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81

Query: 356 SQSPDCKDGAAATGATATPS 375
           S     +  + A  AT T S
Sbjct: 82  SFDVSFQQSSTAKSATWTYS 101


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 34.7 bits (78), Expect = 0.27
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 8/94 (8%)

Query: 289  QKLKERQNLLKSLE-RDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPR 347
            ++++ R+  +KS   RD +     R+   EL      P KA S+PS   + + R P +P 
Sbjct: 1595 ERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASSAPS---QGKERRPDSPT 1651

Query: 348  QPSLMGPESQSPDCKDGAAATGATATPSAGASGG 381
            +P+L G  S+ P  K  A +    + PS   SGG
Sbjct: 1652 RPTLRG--SEEPTLKHEATSEEVLSPPS--DSGG 1681


>gi|98961156 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|98961154 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|98961152 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|98961150 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|98961148 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|98961143 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|98961146 tetratricopeptide repeat domain 23 [Homo sapiens]
          Length = 447

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 13/146 (8%)

Query: 17  NECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKD 76
           N  ++ VA +S+  R  + Q + LQ  L     +  +LH+ E +A S    ++++Q   +
Sbjct: 11  NHLDEVVAAVSITHR-KKFQNKLLQTALFQPPRE--KLHLCEEKAKSYSNSHEYKQAVHE 67

Query: 77  KVISLLLTHLPL------LKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALI 130
            V  + LT +        L   +++    Y++L       S++  QH E++RQ+L+ +++
Sbjct: 68  LVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLK----GLSLQAKQHAEKARQILANSIV 123

Query: 131 HPATSLEDRSALAMWLNHLEDRTSTS 156
            P +   D    ++ L H   R   S
Sbjct: 124 PPYSENTDVFKFSIELFHTMGRALLS 149


>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
          Length = 1709

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 25/102 (24%), Positives = 38/102 (37%), Gaps = 2/102 (1%)

Query: 290  KLKERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQP 349
            K  + Q +   LE+  +EG S + P+            A    S +   +R    AP  P
Sbjct: 1163 KRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQIFSESSALKRGSDVAPLPP 1222

Query: 350  SLMGPESQSPDCKDGAAATGATATPSAGASGGLQP--HQLSS 389
            +L       P+ K    +   +A P  G S  + P  H L S
Sbjct: 1223 NLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQS 1264


>gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 33.5 bits (75), Expect = 0.61
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 13/107 (12%)

Query: 331 SPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSC 390
           +PS+T  + R  P AP  P+     S SP    G  A+ A A+P+       QP QLS  
Sbjct: 217 TPSSTTSSTRATP-APSAPAAASATSPSPAPSSGNGASTA-ASPT-------QPIQLSDL 267

Query: 391 DGELAVAPLPEGDLPGQFTRVMG----KVCTQLLVSRPDEENISSYL 433
              LA   +P G   GQ   +      ++   +L +   +E +  YL
Sbjct: 268 QSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYL 314


>gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 33.5 bits (75), Expect = 0.61
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 13/107 (12%)

Query: 331 SPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSC 390
           +PS+T  + R  P AP  P+     S SP    G  A+ A A+P+       QP QLS  
Sbjct: 217 TPSSTTSSTRATP-APSAPAAASATSPSPAPSSGNGASTA-ASPT-------QPIQLSDL 267

Query: 391 DGELAVAPLPEGDLPGQFTRVMG----KVCTQLLVSRPDEENISSYL 433
              LA   +P G   GQ   +      ++   +L +   +E +  YL
Sbjct: 268 QSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYL 314


>gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Homo
           sapiens]
          Length = 722

 Score = 33.1 bits (74), Expect = 0.79
 Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 22/118 (18%)

Query: 473 LDISGYRQQRN---RGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSG 529
           LD +  RQ       GF + +SLP++  +G   G     Q  +PS  +P           
Sbjct: 126 LDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLY---QIPLPSSQIPPQ--------- 173

Query: 530 FVSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPS-----RTHSSVQRTRSLPVHTS 582
                   TT  P + ++ R+ L  +  GG N+MPS      + SSV  T    ++TS
Sbjct: 174 --PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTS 229


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 33.1 bits (74), Expect = 0.79
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 20/84 (23%)

Query: 329 YSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSA------GASGGL 382
           Y+SPS TP      P AP  P   G     P       A+GA + P A      GA+ G+
Sbjct: 196 YTSPSATP-----RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGV 250

Query: 383 QPHQLSSCDGELAVAPLPEGDLPG 406
            P +           P+P+G  PG
Sbjct: 251 PPAE---------PEPIPKGSRPG 265



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 10/60 (16%)

Query: 331  SPSTTPEARRREPQA-----PRQPSLMGPESQSPDCKDGAAATGA-----TATPSAGASG 380
            SPS T     RE QA        P+L G    SP C +G   T +       TP  G SG
Sbjct: 2302 SPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSG 2361



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 36/149 (24%), Positives = 58/149 (38%), Gaps = 30/149 (20%)

Query: 263  MMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEGGSL-RIPLQELHQM 321
            M  L+E +LE Q        K+V  ++   +R    +   R++ E  S+ R+ L      
Sbjct: 1526 MSHLSEDELEIQ--------KLVTELESQLQRSKDTRGAPRELAEAESVGRVEL------ 1571

Query: 322  ILTPIKAYSSPSTTPEARRREPQA--PRQPSLMGPE----SQSPDCKDGAAATGATATPS 375
                        T P ++RR  QA  P + +    +     +S   ++GA +  AT    
Sbjct: 1572 ---------GTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAV 1622

Query: 376  AGASGGLQPHQLSSCDGELAVAPLPEGDL 404
             G  GG  P   S   G  A+ P  + DL
Sbjct: 1623 QGRPGGTWPCPASFHPGHAALLPCAQEDL 1651


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 11/88 (12%)

Query: 475  ISGYRQQRNRGFGQSNSLPTAGSVGG-----------GMGRRNPRQYQIPSRNVPSARLG 523
            ++ Y++ RN  F   +  P  G+ GG                  +   IPS N P  ++G
Sbjct: 2067 LATYQENRNTCFSPDHKQPQPGTAGGMRVSVSSKGSISTPNSPVKMTLIPSPNSPFQKVG 2126

Query: 524  LLGTSGFVSSNQRNTTATPTIMKQGRQN 551
             L +S    S+Q +T    T+  Q   N
Sbjct: 2127 KLASSDTGESDQSSTETDSTVKSQEESN 2154


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 36/173 (20%), Positives = 69/173 (39%), Gaps = 16/173 (9%)

Query: 324  TPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQ 383
            TP +  S P  +P  + R+P+ P    L    S  P  +D     G ++  +   S G  
Sbjct: 972  TPQQGASGPGRSPVGQARQPEKPSHLHL-EKASSWPHRRDSGRPPGDSSGQAVAPSEGAN 1030

Query: 384  PHQLSSCDGELAVAPLPEGDLPGQFTRV---MGKVCTQLLVSRPDEENISSYLQLIDKC- 439
             H+  S  G    + LPEG    +   V    G   T +   +  +E +  + +   K  
Sbjct: 1031 KHKGWSRQGLRRPSILPEGSSDSRGPAVEKHPGPSDTVVFREKKPKEVMGGFSRRCSKLI 1090

Query: 440  ----LIHEAFTETQKKRLLSWKQQVQKLFRS-------FPRKTLLDISGYRQQ 481
                L+++ +++    + +  +Q+++ L  +        PRK L+    Y Q+
Sbjct: 1091 NSSQLLYQEYSDVVLNKEIQSQQRLESLSETPGPSSPRQPRKALVSSESYLQR 1143


>gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo
           sapiens]
          Length = 862

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/80 (27%), Positives = 33/80 (41%), Gaps = 6/80 (7%)

Query: 332 PSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAA-----TGATATPSAGASGGL-QPH 385
           PS  P   R  P  PR+P+ +     +    DG++      T      S GA+ GL  P 
Sbjct: 209 PSRPPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNTSEGATSGLIIPL 268

Query: 386 QLSSCDGELAVAPLPEGDLP 405
            +S   G   + P+ +  LP
Sbjct: 269 TISGGSGPRPLNPVTQAPLP 288


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,479,389
Number of Sequences: 37866
Number of extensions: 1230942
Number of successful extensions: 5500
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 5391
Number of HSP's gapped (non-prelim): 191
length of query: 629
length of database: 18,247,518
effective HSP length: 108
effective length of query: 521
effective length of database: 14,157,990
effective search space: 7376312790
effective search space used: 7376312790
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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