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Search of human proteins with 238624149
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238624149 neuroplastin isoform d precursor [Homo sapiens]
(278 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238624149 neuroplastin isoform d precursor [Homo sapiens] 564 e-161
gi|9257240 neuroplastin isoform a precursor [Homo sapiens] 558 e-159
gi|238624147 neuroplastin isoform c precursor [Homo sapiens] 508 e-144
gi|6912646 neuroplastin isoform b precursor [Homo sapiens] 503 e-143
gi|38372919 basigin isoform 1 precursor [Homo sapiens] 170 1e-42
gi|38372925 basigin isoform 2 precursor [Homo sapiens] 170 1e-42
gi|38372923 basigin isoform 4 [Homo sapiens] 155 5e-38
gi|110349719 titin isoform N2-A [Homo sapiens] 69 6e-12
gi|109150416 peroxidasin [Homo sapiens] 67 1e-11
gi|38348215 embigin [Homo sapiens] 67 2e-11
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 60 3e-09
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 60 3e-09
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 57 2e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 57 2e-08
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 55 5e-08
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 55 5e-08
gi|118572606 hemicentin 1 [Homo sapiens] 55 7e-08
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 55 7e-08
gi|126517478 peroxidasin homolog-like [Homo sapiens] 55 7e-08
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 55 9e-08
gi|45594240 limbic system-associated membrane protein [Homo sapi... 54 1e-07
gi|19743806 roundabout 1 isoform b [Homo sapiens] 54 2e-07
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 54 2e-07
gi|4506569 roundabout 1 isoform a [Homo sapiens] 54 2e-07
gi|134244585 putative neuronal cell adhesion molecule [Homo sapi... 54 2e-07
gi|110349717 titin isoform novex-2 [Homo sapiens] 53 3e-07
gi|110349713 titin isoform novex-1 [Homo sapiens] 53 3e-07
gi|110349715 titin isoform N2-B [Homo sapiens] 53 3e-07
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 53 3e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 52 4e-07
>gi|238624149 neuroplastin isoform d precursor [Homo sapiens]
Length = 278
Score = 564 bits (1454), Expect = e-161
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60
MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60
Query: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120
HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA
Sbjct: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN
Sbjct: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240
YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI
Sbjct: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240
Query: 241 IVVYEKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN 278
IVVYEKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN
Sbjct: 241 IVVYEKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN 278
>gi|9257240 neuroplastin isoform a precursor [Homo sapiens]
Length = 282
Score = 558 bits (1439), Expect = e-159
Identities = 278/282 (98%), Positives = 278/282 (98%), Gaps = 4/282 (1%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60
MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60
Query: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120
HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA
Sbjct: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN
Sbjct: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240
YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI
Sbjct: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240
Query: 241 IVVYEKRKRPDEVPD----AGPMKTNSTNNHKDKNLRQRNTN 278
IVVYEKRKRPDEVPD AGPMKTNSTNNHKDKNLRQRNTN
Sbjct: 241 IVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN 282
>gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
Length = 394
Score = 508 bits (1309), Expect = e-144
Identities = 247/248 (99%), Positives = 248/248 (100%)
Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
+PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN
Sbjct: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206
Query: 91 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 150
KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH
Sbjct: 207 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
Query: 151 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS
Sbjct: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
Query: 211 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDK 270
VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDK
Sbjct: 327 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDK 386
Query: 271 NLRQRNTN 278
NLRQRNTN
Sbjct: 387 NLRQRNTN 394
Score = 66.2 bits (160), Expect = 3e-11
Identities = 76/235 (32%), Positives = 96/235 (40%), Gaps = 52/235 (22%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVT--SEEVIIRDSPVLPVTLQCNLTS 58
MSGSSLPSALALSLLLVSGSLLPGPGAAQN + + SE + D+ L C++
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDA----FELYCDVVG 56
Query: 59 S-SHTLTYSYWTKNGVEL-------SATRKNASNMEY--------RINKPRAEDSGEYHC 102
S + + + Y N E + R+ N Y RI + EDSG Y C
Sbjct: 57 SPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYEC 116
Query: 103 VYHFVSAPKAN--------------ATIEVKAAPDI-TGHKRSENKNEGQDATMYCKSVG 147
+ PK N ATI V P I T + + T+ C
Sbjct: 117 --RASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS 174
Query: 148 YPHPDWIWRKKENGMPMDIV--NTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
H +NG+ + N S + INK ED GEY C
Sbjct: 175 SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPR-----------AEDSGEYHC 218
Score = 30.4 bits (67), Expect = 1.8
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMP---MDIVNTSGRFFIINKENYTELNI 186
SE K G +YC VG P P+ W E + + + + + Y +
Sbjct: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
Query: 187 VNLQIT----EDPGEYECNATN 204
L+IT ED G YEC A+N
Sbjct: 99 SVLRITRLTLEDSGTYECRASN 120
>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
Length = 398
Score = 503 bits (1294), Expect = e-143
Identities = 247/252 (98%), Positives = 248/252 (98%), Gaps = 4/252 (1%)
Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
+PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN
Sbjct: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206
Query: 91 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 150
KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH
Sbjct: 207 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
Query: 151 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS
Sbjct: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
Query: 211 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD----AGPMKTNSTNN 266
VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD AGPMKTNSTNN
Sbjct: 327 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNN 386
Query: 267 HKDKNLRQRNTN 278
HKDKNLRQRNTN
Sbjct: 387 HKDKNLRQRNTN 398
Score = 66.2 bits (160), Expect = 3e-11
Identities = 76/235 (32%), Positives = 96/235 (40%), Gaps = 52/235 (22%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVT--SEEVIIRDSPVLPVTLQCNLTS 58
MSGSSLPSALALSLLLVSGSLLPGPGAAQN + + SE + D+ L C++
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDA----FELYCDVVG 56
Query: 59 S-SHTLTYSYWTKNGVEL-------SATRKNASNMEY--------RINKPRAEDSGEYHC 102
S + + + Y N E + R+ N Y RI + EDSG Y C
Sbjct: 57 SPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYEC 116
Query: 103 VYHFVSAPKAN--------------ATIEVKAAPDI-TGHKRSENKNEGQDATMYCKSVG 147
+ PK N ATI V P I T + + T+ C
Sbjct: 117 --RASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS 174
Query: 148 YPHPDWIWRKKENGMPMDIV--NTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
H +NG+ + N S + INK ED GEY C
Sbjct: 175 SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPR-----------AEDSGEYHC 218
Score = 30.4 bits (67), Expect = 1.8
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMP---MDIVNTSGRFFIINKENYTELNI 186
SE K G +YC VG P P+ W E + + + + + Y +
Sbjct: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
Query: 187 VNLQIT----EDPGEYECNATN 204
L+IT ED G YEC A+N
Sbjct: 99 SVLRITRLTLEDSGTYECRASN 120
>gi|38372919 basigin isoform 1 precursor [Homo sapiens]
Length = 385
Score = 170 bits (430), Expect = 1e-42
Identities = 93/237 (39%), Positives = 139/237 (58%), Gaps = 12/237 (5%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 109
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 153 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 208
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 168
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 209 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 268
Query: 169 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 227
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 269 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 328
Query: 228 LGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKDKNLRQRNTN 278
LGI+AE+++LV II +YEKR++P++V D + P+K++ + N K KN+RQRN++
Sbjct: 329 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 385
Score = 28.5 bits (62), Expect = 6.8
Identities = 19/86 (22%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 130 SENKNEGQDATMYCKSVGYPHPDWIW-----------RKKENGMPMDIVNTSGRFFIINK 178
S+ + G ++C++VG P P+ W + +G +D V+ +
Sbjct: 31 SQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYH---- 86
Query: 179 ENYTELNIVNLQITEDPGEYECNATN 204
++ ++ + ED G YEC A+N
Sbjct: 87 QHAASTISIDTLVEEDTGTYECRASN 112
>gi|38372925 basigin isoform 2 precursor [Homo sapiens]
Length = 269
Score = 170 bits (430), Expect = 1e-42
Identities = 93/237 (39%), Positives = 139/237 (58%), Gaps = 12/237 (5%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 109
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 168
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
Query: 169 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 227
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212
Query: 228 LGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKDKNLRQRNTN 278
LGI+AE+++LV II +YEKR++P++V D + P+K++ + N K KN+RQRN++
Sbjct: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
>gi|38372923 basigin isoform 4 [Homo sapiens]
Length = 205
Score = 155 bits (391), Expect = 5e-38
Identities = 82/189 (43%), Positives = 119/189 (62%), Gaps = 10/189 (5%)
Query: 98 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 156
GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W
Sbjct: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76
Query: 157 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215
K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L
Sbjct: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
Query: 216 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKD 269
RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V D + P+K++ + N K
Sbjct: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196
Query: 270 KNLRQRNTN 278
KN+RQRN++
Sbjct: 197 KNVRQRNSS 205
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 68.6 bits (166), Expect = 6e-12
Identities = 53/167 (31%), Positives = 76/167 (45%), Gaps = 18/167 (10%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEY-------RINKPRAEDSGEYHC 102
+ L+C ++ S W +N EL + K NM + IN+ AEDSG+Y C
Sbjct: 6382 IQLECKISGSPEIKVS--WFRNDSELHESWKY--NMSFINSVALLTINEASAEDSGDYIC 6437
Query: 103 VYHF-VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
H V + + VKA P T +G D + C+ G P + +W K
Sbjct: 6438 EAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ 6497
Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208
V S +F I +K T L+I+NL+ + D GEY C ATN +GS
Sbjct: 6498 -----VRNSKKFKITSKHFDTSLHILNLEAS-DVGEYHCKATNEVGS 6538
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 13/129 (10%)
Query: 95 EDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP--HP 151
EDSG+Y C H + +++T ++VK P +G D + C+ G P H
Sbjct: 7371 EDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHV 7430
Query: 152 DWIWRKKENGMPMDIVNTSGRFFIINKENY-TELNIVNLQITEDPGEYECNATNAIGSAS 210
W K+E SG+ + I EN+ T ++I+N+ D GEY+C ATN +GS +
Sbjct: 7431 SWYKDKREL--------RSGKKYKIMSENFLTSIHILNVDAA-DIGEYQCKATNDVGSDT 7481
Query: 211 VVTVLRVRS 219
V + +++
Sbjct: 7482 CVGSIALKA 7490
Score = 53.5 bits (127), Expect = 2e-07
Identities = 41/173 (23%), Positives = 78/173 (45%), Gaps = 14/173 (8%)
Query: 52 LQCNLTSSSHTLTYSYWTKNGVELSATRKNA-----SNMEYRINKPRAEDSGEYHC-VYH 105
L+C + S W +N EL A+ K S ++N EDSG++ C +
Sbjct: 5443 LECKIAGSPEIRVV--WFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQN 5500
Query: 106 FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 165
+ + + VK P + + + ++ C+ G P + +W K + +
Sbjct: 5501 PAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQL--- 5557
Query: 166 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
+S ++ I +K +T ++I+N+ T D GEY C A N +GS + V ++++
Sbjct: 5558 --RSSKKYKIASKNFHTSIHILNVD-TSDIGEYHCKAQNEVGSDTCVCTVKLK 5607
Score = 53.1 bits (126), Expect = 3e-07
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117
W NGVEL+ + + + S+ I + D G C+ + + + T+ E
Sbjct: 33070 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 33129
Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177
+ AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I
Sbjct: 33130 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 33184
Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
N L I N ++ D G+Y A N G S L V
Sbjct: 33185 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 33223
Score = 49.3 bits (116), Expect = 4e-06
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 68 WTKNGVELSATRK-NASNME----YRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAA 121
W KNG+ ++ +++ N + E I ED+G+Y+C S + +A I +
Sbjct: 7901 WKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 7960
Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
P + G A++ C+ G P W K + + T+ + N
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRP---TTTYKMHFRNNVAT 8017
Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
N V++ D GEY C A N++G S T L V+ P
Sbjct: 8018 LVFNQVDIN---DSGEYICKAENSVGEVSASTFLTVQEQKLP 8056
Score = 48.9 bits (115), Expect = 5e-06
Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 17/197 (8%)
Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
EP + + I+ + TL+C + + T W K+G EL++ K + +++
Sbjct: 7584 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYKISFFNKVS 7641
Query: 91 KPRA-----EDSGEYHC-VYHFVSAPKANATIEVK---AAPDITGHKRSENKNEGQDATM 141
+ DSG Y V + V A+++V P T + N G M
Sbjct: 7642 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVM 7701
Query: 142 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 201
CK G P W + N + +SGR + + T VN+ D G+Y C
Sbjct: 7702 ECKVYGSPPISVSWFHEGNEI------SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 7755
Query: 202 ATNAIGSASVVTVLRVR 218
ATN GS L VR
Sbjct: 7756 ATNMAGSDECSAPLTVR 7772
Score = 47.8 bits (112), Expect = 1e-05
Identities = 47/206 (22%), Positives = 88/206 (42%), Gaps = 30/206 (14%)
Query: 26 GAAQNEPRIVTSE--EVIIRDSPVLPV------TLQCNLTSSSHTLTYSYWTKNGVELSA 77
G A ++ + E + I + SPVL + T +C +T + W +G E++A
Sbjct: 4847 GTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVS--WYLDGNEITA 4904
Query: 78 TRKNASNM-----EYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSE 131
+K+ + ++I+ R E+SG Y C + + ++VK P +
Sbjct: 4905 IQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPV 4964
Query: 132 NKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQI 191
+ D + C+ G P + W K + +S ++ + ++ +++ NL I
Sbjct: 4965 EVVKYSDVELECEVTGTPPFEVTWLKNNRE-----IRSSKKYTLTDR-----VSVFNLHI 5014
Query: 192 TE----DPGEYECNATNAIGSASVVT 213
T+ D GEY+C +N GS S T
Sbjct: 5015 TKCDPSDTGEYQCIVSNEGGSCSCST 5040
Score = 47.0 bits (110), Expect = 2e-05
Identities = 42/158 (26%), Positives = 67/158 (42%), Gaps = 13/158 (8%)
Query: 68 WTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121
W+K+G +L + E +I + +DSG Y C + + +AT+ V+
Sbjct: 3677 WSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP 3736
Query: 122 PDITGH-KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
P S G+ A ++CK G P W K N + NT R + +N E
Sbjct: 3737 PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK--NNKELSESNTV-RMYFVNSEA 3793
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
++ V + ED G Y C A N +GS S T + ++
Sbjct: 3794 ILDITDVKV---EDSGSYSCEAVNDVGSDSCSTEIVIK 3828
Score = 46.2 bits (108), Expect = 3e-05
Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 31/213 (14%)
Query: 26 GAAQNEPRIVTSEEVIIRDSPVLPV----------TLQCNLTSSSHTLTYSYWTKNGVEL 75
G A + +++ SE + + PV T +C++T ++ W K+ E+
Sbjct: 7195 GTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT--WAKDNREI 7252
Query: 76 --------SATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITG 126
+ A+ ++ K D+G+Y C + +A + V+ P
Sbjct: 7253 RPGGNYKMTLVENTATLTVLKVGKG---DAGQYTCYASNIAGKDSCSAQLGVQEPPRFIK 7309
Query: 127 HKRSENKNEGQDATMY-CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELN 185
+ + T Y CK G P +W K E + S +F + ++ L
Sbjct: 7310 KLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETE-----IQESSKFRMSFVDSVAVLE 7364
Query: 186 IVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
+ NL + ED G+Y C A NA GSAS T L+V+
Sbjct: 7365 MHNLSV-EDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 45.1 bits (105), Expect = 7e-05
Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 8/134 (5%)
Query: 88 RINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH-KRSENKNEGQDATMYCKS 145
RI K DSG+Y C + V +A + VK P + S+ +G+ + CK
Sbjct: 6329 RILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKI 6388
Query: 146 VGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNA 205
G P W + ++ + + S ++ + + N L +N ED G+Y C A N
Sbjct: 6389 SGSPEIKVSWFRNDSEL-----HESWKYNM-SFINSVALLTINEASAEDSGDYICEAHNG 6442
Query: 206 IGSASVVTVLRVRS 219
+G AS T L V++
Sbjct: 6443 VGDASCSTALTVKA 6456
Score = 44.7 bits (104), Expect = 9e-05
Identities = 39/162 (24%), Positives = 59/162 (36%), Gaps = 12/162 (7%)
Query: 68 WTKNGVELSATRK-NASNME----YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA 121
W K+G ++ + K N E I D+G+Y C + + A +
Sbjct: 6019 WKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP 6078
Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
P G ++ C+ G P W K + + R + N
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRP---TPEYRTYFTNNVAT 6135
Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
N VN+ D GEY C A N+IG+AS TV R++ P
Sbjct: 6136 LVFNKVNIN---DSGEYTCKAENSIGTASSKTVFRIQERQLP 6174
Score = 43.9 bits (102), Expect = 2e-04
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 20/152 (13%)
Query: 68 WTKNGVELSATRKNA-----SNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA 121
W N E+ + K+ S R+ EDSGEY C + + ++ + VK +
Sbjct: 4333 WFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKES 4392
Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
P T + + D + + G P + W K + SGR + + +
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNT------ILRSGRKY----KTF 4442
Query: 182 TELNIVNLQITE----DPGEYECNATNAIGSA 209
+ ++V+LQI + D GEY+C TN +GS+
Sbjct: 4443 IQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 4474
Score = 43.5 bits (101), Expect = 2e-04
Identities = 47/206 (22%), Positives = 80/206 (38%), Gaps = 29/206 (14%)
Query: 20 SLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATR 79
S L PG Q P + I++ +P + W K+ VEL +
Sbjct: 5331 SFLVKPGRQQAIPDSTVEFKAILKGTPPFKIK----------------WFKDDVELVSGP 5374
Query: 80 KNASNME-----YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH-KRSEN 132
K +E + A +G+Y C V + V + + V P + S+
Sbjct: 5375 KCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKI 5434
Query: 133 KNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT 192
G + + CK G P +W + E+ +P S ++ + ++ + + NL T
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELP-----ASDKYRMTFIDSVAVIQMNNLS-T 5488
Query: 193 EDPGEYECNATNAIGSASVVTVLRVR 218
ED G++ C A N GS S T + V+
Sbjct: 5489 EDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 14/162 (8%)
Query: 52 LQCNLTSSSHTLTYSYWTKNGVELSAT---RKNASNME--YRINKPRAEDSGEYHC-VYH 105
L C L S + W KN ELS + R N E I + EDSG Y C +
Sbjct: 3757 LHCKLKGSP--VIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN 3814
Query: 106 FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 165
V + + I +K P + G +A + C+ G + W K +
Sbjct: 3815 DVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQ---- 3870
Query: 166 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
+ +S ++ + ++++ L I + + D GEYEC N +G
Sbjct: 3871 -IRSSKKYRLFSQKSLVCLEIFSFN-SADVGEYECVVANEVG 3910
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 16/150 (10%)
Query: 68 WTKNGVELSATRK-NASNMEY----RINKPRAEDSGEYHCV----YHFVSAPKANATIEV 118
W K G E+ + K + + +Y I + + D GEY C Y VS A T+
Sbjct: 3489 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT-ATLTVTE 3547
Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
P +S G+ A C G P + IW+K + + S + I +
Sbjct: 3548 AYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAAL-----SPSPNWRISDA 3602
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGS 208
EN L + NL I +D G Y C A+N G+
Sbjct: 3603 ENKHILELSNLTI-QDRGVYSCKASNKFGA 3631
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 18/159 (11%)
Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAA 121
W K+G E+S + K + ++ +N ED+ Y C V+ A + + VK
Sbjct: 5270 WFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP 5329
Query: 122 PDITGHKRSENKNEGQDATMYCKSV--GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179
P + + D+T+ K++ G P W K D+ SG I E
Sbjct: 5330 PSFL--VKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKD------DVELVSGPKCFIGLE 5381
Query: 180 NYTE-LNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
T LN+ ++ ++ G+Y C+ TN +GS S T+L V
Sbjct: 5382 GSTSFLNLYSVDASKT-GQYTCHVTNDVGSDSCTTMLLV 5419
Score = 40.4 bits (93), Expect = 0.002
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 19/187 (10%)
Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME---- 86
EP +T E V I + P TLQ + + + W K+G EL+ K ++
Sbjct: 4577 EPATITEEAVSIDVTQGDPATLQVKFSGTKEIT--AKWFKDGQELTLGSKYKISVTDTVS 4634
Query: 87 -YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVK---AAPDITGHKRSENKNEGQDATM 141
+I +DSGEY V + V A I V P T + + +G +
Sbjct: 4635 ILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDL 4694
Query: 142 YCKSVGYPHPDWI-WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
C G HP I W K + ++ S ++ +N L I L+ T D G Y C
Sbjct: 4695 ECIVAG-SHPISIQWFKDDQE-----ISASEKYKFSFHDNTAFLEISQLEGT-DSGTYTC 4747
Query: 201 NATNAIG 207
+ATN G
Sbjct: 4748 SATNKAG 4754
Score = 40.4 bits (93), Expect = 0.002
Identities = 50/229 (21%), Positives = 88/229 (38%), Gaps = 23/229 (10%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRI-----NKPRAEDSGEYHCVY 104
V+LQC + + +T S W K +L T + + + NK DSGEY C
Sbjct: 6096 VSLQCQVAGTPE-ITVS-WYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 6153
Query: 105 HFVSAPKANATI----EVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKEN 160
++ T+ E + P + + G T+ C+ G W + +
Sbjct: 6154 ENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR-DG 6212
Query: 161 GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSH 220
+ D N F +N L I+ ++ G+Y C+A+N +G+AS L R
Sbjct: 6213 VLLRDDENLQTSFV----DNVATLKILQTDLSHS-GQYSCSASNPLGTASSSARLTARE- 6266
Query: 221 LAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKD 269
P +I + + ++ E V A PM+ + ++K+
Sbjct: 6267 -----PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKE 6310
Score = 39.7 bits (91), Expect = 0.003
Identities = 40/181 (22%), Positives = 73/181 (40%), Gaps = 14/181 (7%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCV 103
P+ L+ T + ++ S W K+ +S + + + M + I + ED +Y C+
Sbjct: 6943 PIVLEATYTGTP-PISVS-WIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 7000
Query: 104 YHFVSAPK-ANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162
+ A + V P G+ AT+ CK G P W K+ +
Sbjct: 7001 IENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKL 7060
Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222
++ + + K N L ++N D GEY C A N++G+ + VL +++
Sbjct: 7061 -----RSAPAYKMQFKNNVASL-VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKL 7114
Query: 223 P 223
P
Sbjct: 7115 P 7115
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121
W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A
Sbjct: 30566 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 30625
Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
P G+ E +T+ + +G P P W + ++ S I N
Sbjct: 30626 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 30680
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
E+YT L + N+Q G+Y+ +N G+ + + ++
Sbjct: 30681 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 30720
Score = 39.3 bits (90), Expect = 0.004
Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 16/114 (14%)
Query: 38 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK-----P 92
++V +++ +T Q ++ + S W +NG L ++ + +E++++K
Sbjct: 8752 QDVTLKEGQTCTMTCQFSVPNVK-----SEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 8806
Query: 93 RAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSEN--KNEGQDATMYCK 144
RAED G+Y C Y + + +A + ++A P I KR +N +E Q AT C+
Sbjct: 8807 RAEDQGQYTCKYEDL---ETSAELRIEAEP-IQFTKRIQNIVVSEHQSATFECE 8856
Score = 38.9 bits (89), Expect = 0.005
Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 31/197 (15%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR-------INKPRAEDSGEYH 101
P TLQC + + W K +L + A M+++ INK D GEY
Sbjct: 7036 PATLQCKVDGTPEIRIS--WYKEHTKLRSAP--AYKMQFKNNVASLVINKVDHSDVGEYS 7091
Query: 102 C-VYHFVSAPKANATIEVKAA---PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 157
C + V A ++A + +KA P + ++ G C+ G W K
Sbjct: 7092 CKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYK 7151
Query: 158 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDP----GEYECNATNAIGSASVVT 213
+ + D N F N+ LQI + G+Y C+A+N +G+AS
Sbjct: 7152 -DGVLLKDDANLQTSFVH---------NVATLQILQTDQSHIGQYNCSASNPLGTASSSA 7201
Query: 214 VLRVRSHLAPLWPFLGI 230
L + H P PF +
Sbjct: 7202 KLILSEHEVP--PFFDL 7216
Score = 38.5 bits (88), Expect = 0.007
Identities = 47/178 (26%), Positives = 73/178 (41%), Gaps = 20/178 (11%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVEL-------SATRKNASNMEYRINKPRAEDSGEYHC 102
V L+C ++ S+ W ++G E+ S+ +N + + +P D+G Y C
Sbjct: 6758 VVLECRVSGSAPISVG--WFQDGNEIVSGPKCQSSFSENVCTLNLSLLEP--SDTGIYTC 6813
Query: 103 VYHFVS-APKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
V V+ + + +A + V+ P S G T G P W K
Sbjct: 6814 VAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE 6873
Query: 162 M-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
+ P + N S F+ TEL + +Q E G+Y C TN GSAS T L V+
Sbjct: 6874 LVPGESCNISLEDFV------TELELFEVQPLES-GDYSCLVTNDAGSASCTTHLFVK 6924
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%)
Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168
A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I
Sbjct: 934 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 993
Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
SG ++ +E + ED G + C+A N G+ S L V+
Sbjct: 994 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 38.1 bits (87), Expect = 0.009
Identities = 44/195 (22%), Positives = 77/195 (39%), Gaps = 25/195 (12%)
Query: 42 IRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME---------YRINKP 92
++++ LPV C + S S ++ S W K+G L K++ N++ I K
Sbjct: 8066 VQETVGLPVVFDCAI-SGSEPISVS-WYKDGKPL----KDSPNVQTSFLDNTATLNIFKT 8119
Query: 93 RAEDSGEYHCVY-HFVSAPKANATI---EVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148
+G+Y C + + + ++A + E K P + G+ A C G
Sbjct: 8120 DRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGT 8179
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208
W K + + G++ I EN L ++ + D G+Y C A N +G
Sbjct: 8180 QPIKVSWAKDSRE-----IRSGGKYQISYLENSAHLTVLKVD-KGDSGQYTCYAVNEVGK 8233
Query: 209 ASVVTVLRVRSHLAP 223
S L ++ L P
Sbjct: 8234 DSCTAQLNIKERLIP 8248
Score = 37.7 bits (86), Expect = 0.011
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
+EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q +
Sbjct: 33341 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 33396
Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219
D G Y + N GS S + +RS
Sbjct: 33397 DGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 37.0 bits (84), Expect = 0.019
Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 13/158 (8%)
Query: 68 WTKNGVEL--SATR---KNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA 121
W K+ EL A R K+ ++ + +A DSG Y C + + V + AT+ VK
Sbjct: 4801 WFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860
Query: 122 PD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
P I GQ T C+ G P W +G + + G FI +
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYL--DGNEITAIQKHGISFI---DG 4915
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
I ++ E+ G Y C A N G+AS L+V+
Sbjct: 4916 LATFQISGARV-ENSGTYVCEARNDAGTASCSIELKVK 4952
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I + G+ A + C+ VG P PD W + + R + ++ +
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 30585
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
T V + ED G Y C ATN +G + L +++
Sbjct: 30586 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 30624
Score = 36.6 bits (83), Expect = 0.025
Identities = 51/209 (24%), Positives = 78/209 (37%), Gaps = 23/209 (11%)
Query: 18 SGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQC-NLTSSSHTLTYSYWTKNGVELS 76
SG+L+ Q P VT VLP + C T T W K EL
Sbjct: 4197 SGALI-----VQEPPSFVTKPG----SKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELV 4247
Query: 77 A-----TRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKA-APDITGHKR 129
+ K A + + DSG Y C V + + +A + VK A + +
Sbjct: 4248 SGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEP 4307
Query: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNL 189
S+ +G + CK G P W + + S + + E+ L + ++
Sbjct: 4308 SQLLKKGDATQLACKVTGTPPIKITWFANDRE-----IKESSKHRMSFVESTAVLRLTDV 4362
Query: 190 QITEDPGEYECNATNAIGSASVVTVLRVR 218
I ED GEY C A N GS +++ V+
Sbjct: 4363 GI-EDSGEYMCEAQNEAGSDHCSSIVIVK 4390
Score = 35.8 bits (81), Expect = 0.042
Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 18/143 (12%)
Query: 116 IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFI 175
+E+KAAP I G A C+ P+ + W K + S + I
Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE-----IYESDKCSI 3504
Query: 176 INKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP--------LWPF 227
+ + + L I+ Q+ D GEY C A+N GS S L V P L F
Sbjct: 3505 RSSKYISSLEILRTQVV-DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTF 3563
Query: 228 LGILAEIIILV----VIIVVYEK 246
+G A+ I V VI +++K
Sbjct: 3564 VGKAAKFICTVTGTPVIETIWQK 3586
Score = 35.4 bits (80), Expect = 0.055
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D +
Sbjct: 30919 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 30975
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
+ F K Y +L I ++ +D Y+ ATN GS S L V
Sbjct: 30976 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 31019
Score = 34.7 bits (78), Expect = 0.094
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1524
Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219
GE+ A N G +S+ +L V +
Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEA 1549
Score = 34.7 bits (78), Expect = 0.094
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%)
Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119
W +N + + K+ E +I+ KPR D GEY F++ K A A +E+
Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 12997
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170
AAP I + + G+ TM YP + W K+ + ++T+
Sbjct: 12998 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 13057
Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196
GR+ I+ NK E +NL++ + PG
Sbjct: 13058 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 13091
Score = 33.5 bits (75), Expect = 0.21
Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 21/189 (11%)
Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
EP + +I+ + P TL+ + + W K+G L A++K + + +
Sbjct: 4015 EPAKIIERAELIQVTAGDPATLEYTVAGTPELKPK--WYKDGRPLVASKKYRISFKNNVA 4072
Query: 91 KPR-----AEDSGEYHC-VYHFVSAPKANATIEV---KAAPDITGHKRSENKNEGQDATM 141
+ + DSG+Y + + V + T V AP T R+ + +
Sbjct: 4073 QLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRL 4132
Query: 142 YCKSVGY--PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199
CK G W KE + S R+ I E L I+ + + D G +
Sbjct: 4133 DCKIAGSLPMRVSWFKDGKE-------IAASDRYRIAFVEGTASLEIIRVDMN-DAGNFT 4184
Query: 200 CNATNAIGS 208
C ATN++GS
Sbjct: 4185 CRATNSVGS 4193
Score = 32.3 bits (72), Expect = 0.47
Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%)
Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133
+++ TR++ S+ E+ + + E + + K T+ + I RS
Sbjct: 32517 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 32572
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
EG+ A C + G P P W +K +++TS R + + + I ++Q
Sbjct: 32573 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 32626
Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218
D G Y N+ G L ++
Sbjct: 32627 DEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 32.0 bits (71), Expect = 0.61
Identities = 31/128 (24%), Positives = 46/128 (35%), Gaps = 7/128 (5%)
Query: 97 SGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 155
SG Y C S + A + V+ I +S + E T+ C G P W
Sbjct: 5115 SGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKW 5174
Query: 156 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215
K + R+F ++ EN + + +D G+Y N GS+S L
Sbjct: 5175 LKDGKQI------VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYL 5228
Query: 216 RVRSHLAP 223
RV P
Sbjct: 5229 RVLDQNIP 5236
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
K PDI + EG+ A C+ GYP P W NG ++ S R F +
Sbjct: 1838 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1891
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207
+ L+IV+ + + D GE + A N G
Sbjct: 1892 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1919
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193
EGQ + G P P W K +G P+ + II++ +Y L+I + + E
Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 31861
Query: 194 DPGEYECNATNAIGSASVVTVLRV 217
D G Y ATN GS S L+V
Sbjct: 31862 DTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 31.2 bits (69), Expect = 1.0
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194
G+D + G P P WRK E + D R+ I N ++ + L I Q+T D
Sbjct: 27286 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 27338
Query: 195 PGEYECNATNAIGSASVVTV 214
G+Y N +G TV
Sbjct: 27339 TGKYILTIENGVGEPKSSTV 27358
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2132
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
EL ++ ED A N G S L V++
Sbjct: 2133 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2170
Score = 30.8 bits (68), Expect = 1.4
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114
SH S W KNGVE+ + K ++ ++++ EDS EY V + +A
Sbjct: 2906 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2962
Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174
T+ V P + + E +D + +V Y + W K NG+ + ++ +
Sbjct: 2963 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 3015
Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216
+ K+ LNI N+ D +Y A A +A++ R
Sbjct: 3016 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3056
Score = 30.8 bits (68), Expect = 1.4
Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101
TL C +T H W + G E+ A ++YRI E G YH
Sbjct: 30946 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 30994
Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148
VY + + A++EV+ I K E G+ ++ G
Sbjct: 30995 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 31054
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
P P W+K + D+++ +G + +I ++T L N +D G Y A N G
Sbjct: 31055 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 31108
Score = 30.8 bits (68), Expect = 1.4
Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PKA I K P I + + A K+ G P P IW K + T
Sbjct: 32842 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 32893
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
G + ++++ ++ T D G Y C N+ GS S L +++
Sbjct: 32894 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 32943
Score = 30.4 bits (67), Expect = 1.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P +W K+E + D R I N +EL I+ + +D G Y ATN+
Sbjct: 15130 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 15182
Query: 207 GS 208
GS
Sbjct: 15183 GS 15184
Score = 29.6 bits (65), Expect = 3.0
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179
A P+ +S +G + + G P P + + +G + S F I++E
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155
Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
++ ED G Y NATN++G A+ L V+
Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 29.3 bits (64), Expect = 4.0
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EG T +CK GYP P W K +G + F+ + + +V + ED
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1358
Query: 195 PGEYECNATNAIGSA 209
G Y A+N G+A
Sbjct: 1359 EGIYTAFASNIKGNA 1373
Score = 29.3 bits (64), Expect = 4.0
Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P W + + D + + +N++ + + + D GEY+ +NA
Sbjct: 17536 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 17589
Query: 207 GSASVVTVLRV 217
GS +V L V
Sbjct: 17590 GSKTVAVHLTV 17600
Score = 28.9 bits (63), Expect = 5.2
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDP 195
G AT+ G P W K +G P+ S ++ I K N +L + ++ D
Sbjct: 4031 GDPATLEYTVAGTPELKPKWYK--DGRPLV---ASKKYRISFKNNVAQLKFYSAEL-HDS 4084
Query: 196 GEYECNATNAIGSASVVTVLRV 217
G+Y +N +GS+S T V
Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106
Score = 28.9 bits (63), Expect = 5.2
Identities = 36/161 (22%), Positives = 60/161 (37%), Gaps = 17/161 (10%)
Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATI---EV 118
W KN +E+ T + + ++ K D+G Y C V + + ++I E
Sbjct: 8283 WYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEP 8342
Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM-PMDIVNTSGRFFIIN 177
K P H +EG+ + C G W K + P D + F +
Sbjct: 8343 KKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCS----FSFAS 8398
Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
EL V D G+Y C A+N GS + + + ++
Sbjct: 8399 GTAVLELRDV---AKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 28.9 bits (63), Expect = 5.2
Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+
Sbjct: 18924 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 18977
Query: 207 GS 208
G+
Sbjct: 18978 GT 18979
Score = 28.5 bits (62), Expect = 6.8
Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP T +S EG AT G+P P+ W + +G + G I +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
+L I + + G Y ATN G A+ L V++ AP
Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103
Score = 28.1 bits (61), Expect = 8.8
Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149
DSGE+ V +S +E + P ++ N EG M ++ G P
Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1583
Query: 150 HPDWIWRKKEN 160
+PD +W K +
Sbjct: 1584 NPDIVWLKNSD 1594
Score = 28.1 bits (61), Expect = 8.8
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
G P P W K E + P D + + + + E TEL+I + ED G Y A+N
Sbjct: 15424 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 15481
Query: 205 AIGS 208
+GS
Sbjct: 15482 RLGS 15485
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 67.4 bits (163), Expect = 1e-11
Identities = 59/207 (28%), Positives = 88/207 (42%), Gaps = 25/207 (12%)
Query: 27 AAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSY-----------WTKNGVEL 75
A N + + +I++ P VT Q + T+ + WTK G +L
Sbjct: 414 ATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 473
Query: 76 SATRKNA--SNMEYRINKPRAEDSGEYHC-VYHFVSAPK--ANATIEVKAAPDITGHKRS 130
S R++ S+ RI+ D G+Y C + + + K A+ T++ + P
Sbjct: 474 SVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSD 533
Query: 131 ENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQ 190
G + + C S G P P W K +G+ V SG+F I + E + +N V
Sbjct: 534 TTVEVGANVQLPCSSQGEPEPAITWNK--DGVQ---VTESGKFHI-SPEGFLTINDVG-- 585
Query: 191 ITEDPGEYECNATNAIGSASVVTVLRV 217
D G YEC A N IGSASV VL V
Sbjct: 586 -PADAGRYECVARNTIGSASVSMVLSV 611
Score = 56.6 bits (135), Expect = 2e-08
Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 10/131 (7%)
Query: 96 DSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154
DSGEY C + + + A A I V+A P T + EGQ C++ G P P
Sbjct: 406 DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIA 465
Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214
W K + + +D R ++ ++ V L D G+YEC A N IGS VV
Sbjct: 466 WTKGGSQLSVD------RRHLVLSSGTLRISGVALH---DQGQYECQAVNIIGSQKVVAH 516
Query: 215 LRVRSHLAPLW 225
L V+ + P++
Sbjct: 517 LTVQPRVTPVF 527
Score = 44.7 bits (104), Expect = 9e-05
Identities = 39/165 (23%), Positives = 63/165 (38%), Gaps = 25/165 (15%)
Query: 68 WTKNGVELSATRKNASNM----EYRINKPRAEDSGEYHCVYHFVSAPKANATIEVK---- 119
W +N ELS + N+ I + D G Y C+ V+ + ++
Sbjct: 279 WLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGS 338
Query: 120 -AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW-RKKENGMPMD---IVNTSGRFF 174
A P ++ G+ T+ C + G+P P W R +P+D + SG +
Sbjct: 339 PARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLY 398
Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
I N + D GEY C+ATN I S + V++
Sbjct: 399 IQN------------VVQGDSGEYACSATNNIDSVHATAFIIVQA 431
Score = 38.5 bits (88), Expect = 0.007
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 7/93 (7%)
Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
P IT + + G C++ G P P+ IW + N + M T R +++
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSM---KTDSRLNLLDDGT- 301
Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTV 214
L I N Q T D G Y+C A N G V
Sbjct: 302 --LMIQNTQET-DQGIYQCMAKNVAGEVKTQEV 331
>gi|38348215 embigin [Homo sapiens]
Length = 327
Score = 67.0 bits (162), Expect = 2e-11
Identities = 65/249 (26%), Positives = 101/249 (40%), Gaps = 29/249 (11%)
Query: 50 VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 102
V L C T+S + W K+G +L SAT +YR ++ G Y C
Sbjct: 84 VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142
Query: 103 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162
+ + +V P++ G + G + CK +W W NG
Sbjct: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198
Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 221
V ++IN E + Q+ E+ GE Y C A +G + L V S+L
Sbjct: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258
Query: 222 APLWPFLGILAEIIILVVIIVVYE-----KRKRPDE-----------VPDAGPMKTNSTN 265
PL PFL I+AE+I+LV I++ E K+K DE D+ ++ N
Sbjct: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318
Query: 266 NHKDKNLRQ 274
+ K+++L Q
Sbjct: 319 HRKNESLGQ 327
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 59.7 bits (143), Expect = 3e-09
Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 30/237 (12%)
Query: 10 LALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQC--NLTSSSHTLT 64
L+ + L + G G + E RI+ E+ +D V+ P T+Q N+ +++ L
Sbjct: 169 LSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLG 228
Query: 65 YSY---------------WTKNGVELSATRKNAS------NMEYRINKPRAEDSGEYHCV 103
S WTK+G ++ + + + I K D EY C+
Sbjct: 229 QSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICI 288
Query: 104 YHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
A + +ATI +K A P IT + + T+ C++ G P P WR
Sbjct: 289 AEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRN 347
Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
+ + G + + + L + ++Q T D GEY C A+N IG S L V+
Sbjct: 348 ISSEEKTLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTASNTIGQDSQSMYLEVQ 403
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query: 54 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 106
C + + S+++ NG +L+ ++ S + I +D+G Y CV
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100
Query: 107 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
++ AT+ VK + + EG+DA + C V P IW+ K
Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
D++ FI+ NY ++ + D G Y C
Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189
Score = 37.7 bits (86), Expect = 0.011
Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 26/131 (19%)
Query: 96 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154
D+GEY C + + + +EV+ AP + G EG + C+ YP
Sbjct: 379 DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATIS 437
Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECNATN 204
W + +P NY+ + I N L++T D G Y C A N
Sbjct: 438 WFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 483
Query: 205 AIGSASVVTVL 215
IG S+ +L
Sbjct: 484 RIGQESLEFIL 494
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 59.7 bits (143), Expect = 3e-09
Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 30/237 (12%)
Query: 10 LALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQC--NLTSSSHTLT 64
L+ + L + G G + E RI+ E+ +D V+ P T+Q N+ +++ L
Sbjct: 169 LSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLG 228
Query: 65 YSY---------------WTKNGVELSATRKNAS------NMEYRINKPRAEDSGEYHCV 103
S WTK+G ++ + + + I K D EY C+
Sbjct: 229 QSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICI 288
Query: 104 YHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
A + +ATI +K A P IT + + T+ C++ G P P WR
Sbjct: 289 AEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRN 347
Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
+ + G + + + L + ++Q T D GEY C A+N IG S L V+
Sbjct: 348 ISSEEKTLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTASNTIGQDSQSMYLEVQ 403
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query: 54 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 106
C + + S+++ NG +L+ ++ S + I +D+G Y CV
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100
Query: 107 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
++ AT+ VK + + EG+DA + C V P IW+ K
Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
D++ FI+ NY ++ + D G Y C
Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189
Score = 37.7 bits (86), Expect = 0.011
Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 26/131 (19%)
Query: 96 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154
D+GEY C + + + +EV+ AP + G EG + C+ YP
Sbjct: 379 DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATIS 437
Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECNATN 204
W + +P NY+ + I N L++T D G Y C A N
Sbjct: 438 WFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 483
Query: 205 AIGSASVVTVL 215
IG S+ +L
Sbjct: 484 RIGQESLEFIL 494
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 56.6 bits (135), Expect = 2e-08
Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 12/182 (6%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK 91
P + S +R PV+L C + + L +W K+G L +++ + ++
Sbjct: 767 PPQIASSAPTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHL 825
Query: 92 PRA--EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148
RA E +G Y CV + + + + V+ P I NEG A++ C + G
Sbjct: 826 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGV 885
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208
P P W K+ N + + G + ++KE ++ +D G Y C ATN +G
Sbjct: 886 PAPTITWTKETNAL-----TSRGPHYNVSKEGTL---LIAQPSAQDAGAYVCTATNTVGF 937
Query: 209 AS 210
+S
Sbjct: 938 SS 939
Score = 55.5 bits (132), Expect = 5e-08
Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 3/157 (1%)
Query: 68 WTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITG 126
W + G+E+ + +S+ + RI + D+G Y C + + A + V AP +T
Sbjct: 614 WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTE 673
Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186
R G+ A + C++ G P P WR+ + G P+ + +GR + + L
Sbjct: 674 LPRDVTVELGRSALLACRATGRPPPTVTWRRGD-GQPLGLRLGAGRGSRSRQPDSGVLFF 732
Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
++ ED Y C A N G L V H P
Sbjct: 733 ESV-APEDQAPYVCEARNVFGKVQAEARLIVTGHAPP 768
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 25/185 (13%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEY 87
P++V + V + SP L C L + + LT W ++ L A+ + ++
Sbjct: 401 PQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSL 455
Query: 88 RINKPRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146
I+ D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C +
Sbjct: 456 EISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSAS 515
Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203
GYP P W ++ + D V+ G I+ ED G Y C AT
Sbjct: 516 GYPTPHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQAT 563
Query: 204 NAIGS 208
N +G+
Sbjct: 564 NEVGT 568
Score = 45.8 bits (107), Expect = 4e-05
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 23/183 (12%)
Query: 48 LPVTLQCNLTS-SSHTLTYSYWTK--NGVELSATRKNASNM-EYRINKPRAEDSGEYHCV 103
+P +L C + + T+T WTK N + N S I +P A+D+G Y C
Sbjct: 874 VPASLPCVASGVPAPTIT---WTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCT 930
Query: 104 YHFV---SAPKANATIEVKAAPDITGHKRSE-----NKNEGQDATMYCKSVGYPHPDWIW 155
S+ + ++ K + G + + G++ T+ C++ G P P W
Sbjct: 931 ATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTW 990
Query: 156 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215
K +P + R+ ++ + L + +Q+ D G YEC A+N GSAS VL
Sbjct: 991 TKDSRPVPP----ITNRYGLLPSGS---LRLAQVQVG-DSGHYECTASNPAGSASHRYVL 1042
Query: 216 RVR 218
V+
Sbjct: 1043 GVQ 1045
Score = 38.9 bits (89), Expect = 0.005
Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 18/127 (14%)
Query: 95 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153
ED+G Y C + V + T+ P ++ G++A + C++ G P P
Sbjct: 553 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV 612
Query: 154 IWRKKENGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
IW + G+ M + ++SG+ I + D G Y C A N +G AS
Sbjct: 613 IWYR--GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDAS 658
Query: 211 VVTVLRV 217
L V
Sbjct: 659 AEIQLAV 665
Score = 29.3 bits (64), Expect = 4.0
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 80 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 138
+ + N + I + + G Y C +A A I V P + + G+
Sbjct: 357 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 416
Query: 139 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 194
A + C+ +G + W + +P ++GR +L ++L+I+ D
Sbjct: 417 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 464
Query: 195 PGEYECNATNAIGSASVVTVLRVR 218
G Y+C A+NA G L VR
Sbjct: 465 GGRYQCVASNANGVTRASVWLLVR 488
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 56.6 bits (135), Expect = 2e-08
Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 12/182 (6%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK 91
P + S +R PV+L C + + L +W K+G L +++ + ++
Sbjct: 884 PPQIASSAPTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHL 942
Query: 92 PRA--EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148
RA E +G Y CV + + + + V+ P I NEG A++ C + G
Sbjct: 943 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGV 1002
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208
P P W K+ N + + G + ++KE ++ +D G Y C ATN +G
Sbjct: 1003 PAPTITWTKETNAL-----TSRGPHYNVSKEGTL---LIAQPSAQDAGAYVCTATNTVGF 1054
Query: 209 AS 210
+S
Sbjct: 1055 SS 1056
Score = 55.5 bits (132), Expect = 5e-08
Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 3/157 (1%)
Query: 68 WTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITG 126
W + G+E+ + +S+ + RI + D+G Y C + + A + V AP +T
Sbjct: 731 WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTE 790
Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186
R G+ A + C++ G P P WR+ + G P+ + +GR + + L
Sbjct: 791 LPRDVTVELGRSALLACRATGRPPPTVTWRRGD-GQPLGLRLGAGRGSRSRQPDSGVLFF 849
Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
++ ED Y C A N G L V H P
Sbjct: 850 ESV-APEDQAPYVCEARNVFGKVQAEARLIVTGHAPP 885
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 25/185 (13%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEY 87
P++V + V + SP L C L + + LT W ++ L A+ + ++
Sbjct: 518 PQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSL 572
Query: 88 RINKPRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146
I+ D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C +
Sbjct: 573 EISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSAS 632
Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203
GYP P W ++ + D V+ G I+ ED G Y C AT
Sbjct: 633 GYPTPHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQAT 680
Query: 204 NAIGS 208
N +G+
Sbjct: 681 NEVGT 685
Score = 52.4 bits (124), Expect = 4e-07
Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 17/160 (10%)
Query: 68 WTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124
W K G+ ++ + + + RI ED+G Y C+ + + + V+ P I
Sbjct: 3981 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 4040
Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184
+ EG A + CK+ G P P+ W K +G P + G+F I + EL
Sbjct: 4041 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--VSGAEGKFTI---QPSGEL 4093
Query: 185 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 224
+ NL+ +D G Y C A NA+G A R R HL L
Sbjct: 4094 LVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 4126
Score = 50.1 bits (118), Expect = 2e-06
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 12/162 (7%)
Query: 67 YWTKNGVEL--SATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123
+W K+G+ L S R N I++ +D+G Y C+ + + K + +++AP
Sbjct: 4251 HWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPV 4310
Query: 124 ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 183
+ G D + C++ G P P W + G P+ S R + +
Sbjct: 4311 FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQA--GQPL---RASRRLRTLPDGSLWL 4365
Query: 184 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLW 225
N+ T D G Y+C A N +GSA+ L VR W
Sbjct: 4366 ENVE----TGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSW 4403
Score = 44.7 bits (104), Expect = 9e-05
Identities = 48/194 (24%), Positives = 74/194 (38%), Gaps = 32/194 (16%)
Query: 25 PGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASN 84
P Q PR++ +V++ ++ L N + + W+K+GV L S
Sbjct: 1119 PPQVQPGPRVL---KVLVGEA------LDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSV 1169
Query: 85 MEYRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSE--NKNEGQDATM 141
I R D+G Y C + A + V P + S + G++A++
Sbjct: 1170 HFAAI---RTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASL 1226
Query: 142 YCKSVGYPHPDWIWRKKEN-----GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPG 196
C + G P P WRK + G P V G F+ + D G
Sbjct: 1227 PCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS------------PADSG 1274
Query: 197 EYECNATNAIGSAS 210
+YEC ATN +GS S
Sbjct: 1275 DYECQATNEVGSTS 1288
Score = 44.3 bits (103), Expect = 1e-04
Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 25/220 (11%)
Query: 17 VSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNG 72
V+GS G N P +T + PVL PV L CN T + S TL W K+G
Sbjct: 1961 VAGSTELRYGLRVNVPPRITLPPSL--PGPVLVNTPVRLTCNATGAPSPTLM---WLKDG 2015
Query: 73 VELSATRKNASNM-----EYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITG 126
+S + + RA DSG Y CV V + + ++V P I G
Sbjct: 2016 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 2075
Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186
+ + + + + C+S P P W K +G P++ G +K L
Sbjct: 2076 EELNVSVVANESVALECQSHAMPPPVLSWWK--DGRPLE--PRPGVHLSADK----ALLQ 2127
Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWP 226
V+ D G Y C A N G + L V +AP++P
Sbjct: 2128 VDRADVWDAGHYTCEALNQAGHSEKHYNLNV--WVAPVFP 2165
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 9/123 (7%)
Query: 96 DSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154
DSG+Y C + + A +E+ P I + N + Q A + C++ G P P
Sbjct: 3646 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVS 3705
Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214
WRK + +P+D S RF I+ + + + + +D G Y C A+N+ GS
Sbjct: 3706 WRK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRD 3757
Query: 215 LRV 217
LRV
Sbjct: 3758 LRV 3760
Score = 42.0 bits (97), Expect = 6e-04
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 88 RINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQD--ATMYCK 144
RI D G Y CV + +A + + V A P I G + +D + C+
Sbjct: 1466 RITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCE 1525
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
+ G P P+ W K +P TS + ++ +L + Q + D G Y C A+N
Sbjct: 1526 ARGVPTPNITWFKDGALLP-----TSTK--VVYTRGGRQLQLGRAQ-SSDAGVYTCKASN 1577
Query: 205 AIGSASVVTVLRV 217
A+G+A T L V
Sbjct: 1578 AVGAAEKATRLDV 1590
Score = 42.0 bits (97), Expect = 6e-04
Identities = 41/167 (24%), Positives = 66/167 (39%), Gaps = 19/167 (11%)
Query: 52 LQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCVY-HFV 107
L CN+T H W K+G L+ A + + ++ + +G Y C+ + V
Sbjct: 2465 LMCNVTG--HPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV 2522
Query: 108 SAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENGM 162
+ + V AP I G E ++ C+++ +P P+ W K +G
Sbjct: 2523 GEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DGA 2580
Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209
P + I L I+N Q ED G+Y C TN +G A
Sbjct: 2581 PFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 2621
Score = 41.6 bits (96), Expect = 8e-04
Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 22/184 (11%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYH 105
PV L+C + H W G+ E + +R R+ P SG Y CV
Sbjct: 1613 PVALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-- 1668
Query: 106 FVSAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKE 159
S+P A ++EV+ P + + GQ + C++ G P P W +
Sbjct: 1669 -ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--Q 1725
Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
NG P + +G + T L+I ++++ + G + C ATN G+A + V
Sbjct: 1726 NGRPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHG 1779
Query: 220 HLAP 223
AP
Sbjct: 1780 EWAP 1783
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 11/123 (8%)
Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE--NKNEGQDATMYCK 144
++ + + +DSG Y C+ + + N ++EV P I E +GQ A + C
Sbjct: 2409 KMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCN 2468
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
G+P P W K +G P+ G I+ + L ++ ++ G Y C A N
Sbjct: 2469 VTGHPQPKLTWFK--DGRPL----ARGDAHHISPDGVL-LQVLQANLS-SAGHYSCIAAN 2520
Query: 205 AIG 207
A+G
Sbjct: 2521 AVG 2523
Score = 40.0 bits (92), Expect = 0.002
Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 16/166 (9%)
Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNG--VELSATRKNASNM-EYRINKPRAEDSGEYHCVY 104
P+ L C+++ + T+T W K+ VE SA S ++++ + +G Y CV
Sbjct: 3141 PLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 3197
Query: 105 HFVSAP-KANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
A + + + V AP I +G R + EGQ+ + C++ G P PD W K +
Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 3257
Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
+ D + RF++ + L + L+ D G Y C A N G
Sbjct: 3258 LGQD-MGPHLRFYL----DGGSLVLKGLR-ASDAGAYTCVAHNPAG 3297
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 23/184 (12%)
Query: 45 SPVLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV 103
+P P+ L C+ + +T W K+G L+ N+ R D+G Y C+
Sbjct: 3508 TPGAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCL 3560
Query: 104 YHF-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKE 159
A + + + V+A P+I G + GQ + C P P W +
Sbjct: 3561 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR-- 3617
Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
+G+ ++ + + +L ++ T D G+Y C A NA GS SV RV
Sbjct: 3618 DGI---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEI 3669
Query: 220 HLAP 223
H P
Sbjct: 3670 HTVP 3673
Score = 38.9 bits (89), Expect = 0.005
Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 18/127 (14%)
Query: 95 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153
ED+G Y C + V + T+ P ++ G++A + C++ G P P
Sbjct: 670 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV 729
Query: 154 IWRKKENGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
IW + G+ M + ++SG+ I + D G Y C A N +G AS
Sbjct: 730 IWYR--GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDAS 775
Query: 211 VVTVLRV 217
L V
Sbjct: 776 AEIQLAV 782
Score = 38.5 bits (88), Expect = 0.007
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 16/127 (12%)
Query: 96 DSGEYHC-VYHFVSAPKANATIEVKAAPDIT--GHKRSENKNEGQDATMYCKSVGYPHPD 152
DSG+Y C + V + A + V P I G K + + GQ T+ C + G+P P+
Sbjct: 1272 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPE 1331
Query: 153 WIWRKKEN--GMPMDIVNTS--------GRFFIINKENYTELNIVNLQITEDPGEYECNA 202
+W K G+P+ G ++++ L+ +Q D G Y C A
Sbjct: 1332 IVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ--SLHFPRIQ-EGDSGLYSCRA 1388
Query: 203 TNAIGSA 209
N G+A
Sbjct: 1389 ENQAGTA 1395
Score = 38.5 bits (88), Expect = 0.007
Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 15/134 (11%)
Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146
+I K D G Y C + K ++V P+I ++ E T+ C +
Sbjct: 1851 QIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 1910
Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203
G P PD W K + + V+ GR L I Q++ D G Y C A+
Sbjct: 1911 GVPPPDVSWFKGHQPVSSWMGVTVSVDGRV----------LRIEQAQLS-DAGSYRCVAS 1959
Query: 204 NAIGSASVVTVLRV 217
N GS + LRV
Sbjct: 1960 NVAGSTELRYGLRV 1973
Score = 35.8 bits (81), Expect = 0.042
Identities = 42/204 (20%), Positives = 75/204 (36%), Gaps = 29/204 (14%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNME 86
P + EE+ + V L+C SH + W K+G L +A
Sbjct: 2070 PPSILGEELNVSVVANESVALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 2125
Query: 87 YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCK 144
++++ D+G Y C + + + + V AP + EG ++ C+
Sbjct: 2126 LQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCE 2185
Query: 145 SVGYPHPDWIWRKKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199
G P P WRK +P + V+ GR + + + G Y
Sbjct: 2186 CRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYT 2234
Query: 200 CNATNAIGSASVVTVLRVRSHLAP 223
C +N +G++S L++ H+ P
Sbjct: 2235 CECSNVVGNSS--QDLQLEVHVPP 2256
Score = 35.4 bits (80), Expect = 0.055
Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
Query: 93 RAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVG 147
RAE++G Y C + V + + V P I G N ++ C ++G
Sbjct: 2812 RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALG 2871
Query: 148 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
P P W +NG+P + S R ++ +++ + D Y C A N G
Sbjct: 2872 NPVPTISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAG 2923
Query: 208 SASVVTVLRVR 218
SA + LRV+
Sbjct: 2924 SAEKLFTLRVQ 2934
Score = 34.3 bits (77), Expect = 0.12
Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 21/134 (15%)
Query: 88 RINKPRAEDSGEYHCVYHFVSAPKANAT----IEVKAAPDITGHKRSENKNEGQDATMYC 143
R+ + + DSG Y C S P +A+ + V+ P + R G+ + C
Sbjct: 1085 RLAQVQVGDSGHYECT---ASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNC 1141
Query: 144 KSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203
+ G P P W K D V GR + + T D G Y C A+
Sbjct: 1142 VAEGNPEPQLSWSK-------DGVVLQGR----GPQGSVHFAAIR---TSDAGRYRCEAS 1187
Query: 204 NAIGSASVVTVLRV 217
N+ G + LRV
Sbjct: 1188 NSAGVDAWEVELRV 1201
Score = 34.3 bits (77), Expect = 0.12
Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 33/200 (16%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
P + ++ + + PV L C+ T + T++ W+K G +L A YR++
Sbjct: 3856 PPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVS 3907
Query: 91 KPRAED--------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATM 141
A + +G Y C + + + V+A+P + ++ +
Sbjct: 3908 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLL 3967
Query: 142 YCKSVGYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEY 198
C++ G P P W+K+ + + V G+ I + ED G Y
Sbjct: 3968 PCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNY 4015
Query: 199 ECNATNAIGSASVVTVLRVR 218
C A N+ GSA T L V+
Sbjct: 4016 LCIAKNSAGSAMGKTRLVVQ 4035
Score = 33.5 bits (75), Expect = 0.21
Identities = 39/185 (21%), Positives = 70/185 (37%), Gaps = 17/185 (9%)
Query: 38 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRA 94
EEV + S V+LQC + + + W +NG+ S + + +++
Sbjct: 2853 EEVTVNASST--VSLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 2908
Query: 95 EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPD 152
D+ Y CV + + + T+ V+ P I G + ++ C +P+P+
Sbjct: 2909 ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE 2968
Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 212
W K + + F++ + +L L D G Y C A NA G +
Sbjct: 2969 VTWYKDSQALSL-----GEEVFLLPGTHTLQLGRARLS---DSGMYTCEALNAAGRDQKL 3020
Query: 213 TVLRV 217
L V
Sbjct: 3021 VQLSV 3025
Score = 32.0 bits (71), Expect = 0.61
Identities = 42/189 (22%), Positives = 73/189 (38%), Gaps = 28/189 (14%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSH-TLTYSYWTKNG----VELSATRKNASNME 86
PR ++ +++D TL+CN T T+T W ++G EL +N
Sbjct: 2261 PREPPTQVSVVQDGVA---TLECNATGKPPPTVT---WERDGQPVGAELGLQLQN-QGQS 2313
Query: 87 YRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEG---QDATMY 142
+ + +A +G Y CV + + + V P++ G T+
Sbjct: 2314 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 2373
Query: 143 CKSVGYPHPDWIWRKKENGMPM--DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
C+++G P P W + E + D +G + + K T+ +D G Y C
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWML--KMTQTQ--------EQDSGLYSC 2423
Query: 201 NATNAIGSA 209
A+N G A
Sbjct: 2424 LASNEAGEA 2432
Score = 31.2 bits (69), Expect = 1.0
Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 8/73 (10%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
E A +YC + P PD W +++ + + ++ ++ +V E+
Sbjct: 2764 ENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR---AEN 2815
Query: 195 PGEYECNATNAIG 207
G Y C A+N +G
Sbjct: 2816 AGRYSCKASNEVG 2828
Score = 30.0 bits (66), Expect = 2.3
Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 12/125 (9%)
Query: 89 INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCK 144
+ + + G Y C + V + +EV P I G + + + QD AT+ C
Sbjct: 2222 LGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECN 2281
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
+ G P P W + +G P+ G + +N + V G Y C A N
Sbjct: 2282 ATGKPPPTVTWER--DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN 2333
Query: 205 AIGSA 209
G A
Sbjct: 2334 LAGRA 2338
Score = 29.3 bits (64), Expect = 4.0
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 80 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 138
+ + N + I + + G Y C +A A I V P + + G+
Sbjct: 474 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 533
Query: 139 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 194
A + C+ +G + W + +P ++GR +L ++L+I+ D
Sbjct: 534 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 581
Query: 195 PGEYECNATNAIGSASVVTVLRVR 218
G Y+C A+NA G L VR
Sbjct: 582 GGRYQCVASNANGVTRASVWLLVR 605
Score = 29.3 bits (64), Expect = 4.0
Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 25/205 (12%)
Query: 26 GAAQNEPRIVTSEEVIIRDS-PVLPVT------LQCNLTSSSH-TLTYSYWTKNGVELSA 77
G+A + R+V +I + P L T L C S +T W K+G +S
Sbjct: 4024 GSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT---WDKDGQPVSG 4080
Query: 78 TRKNAS---NMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENK 133
+ + E + +D+G Y C + V + + + P T +
Sbjct: 4081 AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 4140
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
G + C + G P P W + + T G + ++ + L + E
Sbjct: 4141 RLGDRLWLRCAARGSPTPRIGWTVNDRPV------TEG---VSEQDGGSTLQRAAVS-RE 4190
Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218
D G Y C A N +G V+ + V+
Sbjct: 4191 DSGTYVCWAENRVGRTQAVSFVHVK 4215
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 55.5 bits (132), Expect = 5e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 23/189 (12%)
Query: 54 CNLTSSSHT-LTYSYWTKNGVELSATRKNASN--------MEY----RINKPRAEDSGEY 100
C+ SSS + +T+++ N + A +N ++ MEY R+ + G+Y
Sbjct: 520 CSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKY 579
Query: 101 HCVY--HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK 158
CV HF S+ A + V P T G A + C +VG+P P W +K
Sbjct: 580 QCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAW-QK 638
Query: 159 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 215
+ G R ++ +++ IV+++I ED G Y C A N+ GS S +TVL
Sbjct: 639 DGGTDFPAAR-ERRMHVMPEDDV--FFIVDVKI-EDIGVYSCTAQNSAGSISANATLTVL 694
Query: 216 RVRSHLAPL 224
S L PL
Sbjct: 695 ETPSFLRPL 703
Score = 47.4 bits (111), Expect = 1e-05
Identities = 54/238 (22%), Positives = 93/238 (39%), Gaps = 37/238 (15%)
Query: 52 LQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRINKPRAEDSGEYHCV-Y 104
L+C + H W K+G + A R+ ++ + I + ED G Y C
Sbjct: 622 LEC--AAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQ 679
Query: 105 HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
+ + ANAT+ V P +G+ A + C + G P P W K ++
Sbjct: 680 NSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDS---- 735
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS------ASVVTVLRVR 218
+V T FF +L I+ D G+Y C +N +G+ SV+
Sbjct: 736 PLVVTERHFFAAG----NQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCD 791
Query: 219 S--HLAPL-----WPFLGILAEIII-------LVVIIVVYEKRKRPDEVPDAGPMKTN 262
S AP W +G++ ++ LV ++++Y R+R ++ +TN
Sbjct: 792 SPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETN 849
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 55.5 bits (132), Expect = 5e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 23/189 (12%)
Query: 54 CNLTSSSHT-LTYSYWTKNGVELSATRKNASN--------MEY----RINKPRAEDSGEY 100
C+ SSS + +T+++ N + A +N ++ MEY R+ + G+Y
Sbjct: 460 CSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKY 519
Query: 101 HCVY--HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK 158
CV HF S+ A + V P T G A + C +VG+P P W +K
Sbjct: 520 QCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAW-QK 578
Query: 159 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 215
+ G R ++ +++ IV+++I ED G Y C A N+ GS S +TVL
Sbjct: 579 DGGTDFPAAR-ERRMHVMPEDDV--FFIVDVKI-EDIGVYSCTAQNSAGSISANATLTVL 634
Query: 216 RVRSHLAPL 224
S L PL
Sbjct: 635 ETPSFLRPL 643
Score = 47.4 bits (111), Expect = 1e-05
Identities = 54/238 (22%), Positives = 93/238 (39%), Gaps = 37/238 (15%)
Query: 52 LQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRINKPRAEDSGEYHCV-Y 104
L+C + H W K+G + A R+ ++ + I + ED G Y C
Sbjct: 562 LEC--AAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQ 619
Query: 105 HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
+ + ANAT+ V P +G+ A + C + G P P W K ++
Sbjct: 620 NSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDS---- 675
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS------ASVVTVLRVR 218
+V T FF +L I+ D G+Y C +N +G+ SV+
Sbjct: 676 PLVVTERHFFAAG----NQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCD 731
Query: 219 S--HLAPL-----WPFLGILAEIII-------LVVIIVVYEKRKRPDEVPDAGPMKTN 262
S AP W +G++ ++ LV ++++Y R+R ++ +TN
Sbjct: 732 SPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETN 789
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 55.1 bits (131), Expect = 7e-08
Identities = 48/163 (29%), Positives = 71/163 (43%), Gaps = 12/163 (7%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA--SNMEYRINKPRAEDSGEYHCVYHFV 107
+TL C L + + + W KN L S+ I + + +D GEY CV V
Sbjct: 907 LTLPCTLLAGN-PIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNV 965
Query: 108 SAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 166
+ T + V P I ++ + EG T+ CK+ G P P IW KK ++
Sbjct: 966 AGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKG-----EL 1020
Query: 167 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209
++TS F + L +V+ E+ GEY C ATN G A
Sbjct: 1021 ISTSSAKFSAGADG--SLYVVS-PGGEESGEYVCTATNTAGYA 1060
Score = 53.9 bits (128), Expect = 2e-07
Identities = 54/205 (26%), Positives = 88/205 (42%), Gaps = 31/205 (15%)
Query: 30 NEPRIVT---SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME 86
+EP ++ SE +I ++P+L L C T + + W K G+ ++ + +N + +
Sbjct: 3985 HEPPVIQPQPSELHVILNNPIL---LPCEATGTPSP--FITWQKEGINVNTSGRNHAVLP 4039
Query: 87 ---YRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMY 142
+I++ ED+G Y CV + + V+ P I+ H + + T+
Sbjct: 4040 SGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLS 4099
Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----EDPGEY 198
C++ G P PD W K GR I+ L+ +LQI D G Y
Sbjct: 4100 CEADGLPPPDITWHK------------DGRA-IVESIRQRVLSSGSLQIAFVQPGDAGHY 4146
Query: 199 ECNATNAIGSASVVTVLRVRSHLAP 223
C A N GS+S T L V H+ P
Sbjct: 4147 TCMAANVAGSSSTSTKLTV--HVPP 4169
Score = 52.0 bits (123), Expect = 6e-07
Identities = 49/208 (23%), Positives = 84/208 (40%), Gaps = 31/208 (14%)
Query: 24 GPGAAQ-----NEPRIVTSEEVIIRDSPVLPVTLQCNLTSS-SHTLTYSYWTKNGVELS- 76
G G AQ +EP V + +P L C + S+ + LT W +N ++
Sbjct: 506 GTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLT---WQRNDRDVRL 562
Query: 77 ---ATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSEN 132
A + +N+ + + D+GEYHC+ A + + V+ P +T ++++
Sbjct: 563 AEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQS 622
Query: 133 KNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQI- 191
G + ++ C + GYP P W T FI+ Y + L I
Sbjct: 623 FTGGSEVSIMCSATGYPKPKIAW-------------TVNDMFIVGSHRYRMTSDGTLFIK 669
Query: 192 ---TEDPGEYECNATNAIGSASVVTVLR 216
+D G Y C A+N+ G+ + LR
Sbjct: 670 NAAPKDAGIYGCLASNSAGTDKQNSTLR 697
Score = 49.7 bits (117), Expect = 3e-06
Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 17/179 (9%)
Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNGVEL--SATRKNASNMEYRINKPRAEDSGEYHCVYH 105
P+TL C +T W K+G + S ++ S+ +I + D+G Y C+
Sbjct: 4095 PITLSCEADGLPPPDIT---WHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAA 4151
Query: 106 FVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
V+ + +T + V P I + NE A + C + G P P W KK+N +
Sbjct: 4152 NVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINW-KKDNVL-- 4208
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
+ N G++ E Y EL + N+ + ED G Y C A NA G + L V H+ P
Sbjct: 4209 -LANLLGKY---TAEPYGELILENV-VLEDSGFYTCVANNAAGEDTHTVSLTV--HVLP 4260
Score = 49.3 bits (116), Expect = 4e-06
Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 5/149 (3%)
Query: 88 RINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146
+I + + D+G+Y CV + T++V + P + G + T+ C
Sbjct: 758 KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQ 817
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
GYP P WR+ +N M I + I++ L I+NL D G Y C A N
Sbjct: 818 GYPEPTIKWRRLDN---MPIFSRPFSVSSISQLRTGALFILNLW-ASDKGTYICEAENQF 873
Query: 207 GSASVVTVLRVRSHLAPLWPFLGILAEII 235
G T + V +APL +A +I
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVI 902
Score = 48.5 bits (114), Expect = 6e-06
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 21/188 (11%)
Query: 26 GAAQNEPRIVTSE-EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASN 84
G QN +++ E++ + + P TL H L K G+ +S R
Sbjct: 2108 GEEQNVSVLISQAVELLCQSDAIPPPTL--TWLKDGHPLL----KKPGLSISENRS---- 2157
Query: 85 MEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKN--EGQDATM 141
+I + +D+G Y C + + N + + P+I G EG ++
Sbjct: 2158 -VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISL 2216
Query: 142 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 201
C+S G P P+ IW+KK G P+ + ++ GR I++ +++I D Y C
Sbjct: 2217 LCESSGIPPPNLIWKKK--GSPV-LTDSMGRVRILSGGRQLQISIAE---KSDAALYSCV 2270
Query: 202 ATNAIGSA 209
A+N G+A
Sbjct: 2271 ASNVAGTA 2278
Score = 48.5 bits (114), Expect = 6e-06
Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 11/125 (8%)
Query: 95 EDSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153
EDSG Y CV + + + ++ V P T + N+G+ + CK+ G P P
Sbjct: 4232 EDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 154 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 213
W N +P + +G ++EL ++ ED G Y C A N++G +
Sbjct: 4292 TWTFNNNIIPAHFDSVNG---------HSEL-VIERVSKEDSGTYVCTAENSVGFVKAIG 4341
Query: 214 VLRVR 218
+ V+
Sbjct: 4342 FVYVK 4346
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/156 (25%), Positives = 67/156 (42%), Gaps = 12/156 (7%)
Query: 68 WTKNGV--ELSATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124
W + GV E+S + N I ED+G+Y CV + + + ++ +++ P I
Sbjct: 4383 WNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPII 4442
Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184
T N G + C++ G P P W ++ + + D +N + L
Sbjct: 4443 TLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR--------VNVLSNNSL 4494
Query: 185 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSH 220
I + Q ED E+EC A N +GS V + V+ H
Sbjct: 4495 YIADAQ-KEDTSEFECVARNLMGSVLVRVPVIVQVH 4529
Score = 46.6 bits (109), Expect = 2e-05
Identities = 42/159 (26%), Positives = 65/159 (40%), Gaps = 20/159 (12%)
Query: 68 WTKNGVEL---SATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123
W KNG+ L S R A+ RI + + D Y CV + + ++V A P+
Sbjct: 3376 WLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPN 3435
Query: 124 ITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRKKENGMPMDI---VNTSGRFFIINK 178
+ +E +G +M C + G P P W + + +D V+T G + K
Sbjct: 3436 MDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLK 3495
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
TED G+Y C A+N G S +L+V
Sbjct: 3496 AE-----------TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 45.8 bits (107), Expect = 4e-05
Identities = 50/200 (25%), Positives = 84/200 (42%), Gaps = 26/200 (13%)
Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCV 103
PV L+C + +LT W K+G +S+ + + + D+G Y CV
Sbjct: 2028 PVRLECEARGIPAPSLT---WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCV 2084
Query: 104 YHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162
+ K + + V P+I G +++ + Q + C+S P P W K +G
Sbjct: 2085 AVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLK--DGH 2142
Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222
P ++ G + EN + L I + Q+ +D G Y C ATN G +++
Sbjct: 2143 P--LLKKPG---LSISENRSVLKIEDAQV-QDTGRYTCEATNVAGKTE-------KNYNV 2189
Query: 223 PLW--PFLGILAEIIILVVI 240
+W P +G E+ L VI
Sbjct: 2190 NIWVPPNIGGSDELTQLTVI 2209
Score = 45.8 bits (107), Expect = 4e-05
Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 21/186 (11%)
Query: 27 AAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT---RKNAS 83
A +EPR +T ++R+ V TL+C S + W +NG L AT R +
Sbjct: 3623 AGTDEPRDIT----VLRNRQV---TLECK--SDAVPPPVITWLRNGERLQATPRVRILSG 3673
Query: 84 NMEYRINKPRAEDSGEYHCVYHFVSAPKANATI-EVKAAPDITGHKRSENKNEGQDATMY 142
+IN D+ Y CV ++ I V P+I G +S + +
Sbjct: 3674 GRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE 3733
Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 202
C + G P P WRK + R+ I+ L+I + +T D G Y C A
Sbjct: 3734 CIAEGVPTPRITWRKDG----AVLAGNHARYSILENGF---LHIQSAHVT-DTGRYLCMA 3785
Query: 203 TNAIGS 208
TNA G+
Sbjct: 3786 TNAAGT 3791
Score = 45.4 bits (106), Expect = 5e-05
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 26/172 (15%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCVYHF 106
V+L C +S L W K+G +S + R + R+ + ED+G+Y CV
Sbjct: 2404 VSLTCE--ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRN 2461
Query: 107 VSAPKANAT-IEVKAAPDITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRKKENGMP 163
+ + + V P I G E+ E Q T+ C+ G P P+ W K +G P
Sbjct: 2462 AAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK--DGQP 2519
Query: 164 MD-----IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
+ + + GRF L I N+Q+ G Y C A++ G S
Sbjct: 2520 LQEDEAHHIISGGRF----------LQITNVQVPH-TGRYTCLASSPAGHKS 2560
Score = 45.4 bits (106), Expect = 5e-05
Identities = 50/198 (25%), Positives = 81/198 (40%), Gaps = 24/198 (12%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRI-- 89
P I E +I ++ PVTL C+ T W KN + +N+ ++E RI
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIA--WLKNHKRI----ENSDSLEVRILS 3204
Query: 90 -------NKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDA 139
+ + DSG Y C+ + + + ++ P + G + + + G++
Sbjct: 3205 GGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENV 3264
Query: 140 TMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199
+ C + G P P W K +G P+ T I N + LNI +T D G+Y
Sbjct: 3265 ELVCNANGIPTPLIQWLK--DGKPIASGETER---IRVSANGSTLNIYGA-LTSDTGKYT 3318
Query: 200 CNATNAIGSASVVTVLRV 217
C ATN G + L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336
Score = 44.7 bits (104), Expect = 9e-05
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 26/189 (13%)
Query: 48 LPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS---NMEYRINKPRAEDSGEYHCVY 104
+PVTL C +S + W+K G +S + S + + P E+SGEY C
Sbjct: 996 IPVTLPCK--ASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTA 1053
Query: 105 -HFVSAPKANATIEVKAAPDITGHKRSENKNE--------GQDATMYCKSVGYPHPDWIW 155
+ K + V P + G +R ++++ G++ T+ C+ P P W
Sbjct: 1054 TNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITW 1113
Query: 156 RKKENGM-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214
K+ + P +T F TE T D G Y C ATN G +V
Sbjct: 1114 AKETQLISPFSPRHT---FLPSGSMKITETR------TSDSGMYLCVATNIAG--NVTQA 1162
Query: 215 LRVRSHLAP 223
+++ H+ P
Sbjct: 1163 VKLNVHVPP 1171
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 10/144 (6%)
Query: 68 WTKNGVELSATRKNASNME---YRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123
W K+G L+ S +E I D+G Y C+ + + ++V P
Sbjct: 3746 WRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPS 3805
Query: 124 ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 183
I + T+ C++ G P P WRK NG +++ + +++ +
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK--NGHLLNVDQNQNSYRLLSSGS--- 3860
Query: 184 LNIVNLQITEDPGEYECNATNAIG 207
L I++ + +D YEC TN G
Sbjct: 3861 LVIISPSV-DDTATYECTVTNGAG 3883
Score = 43.5 bits (101), Expect = 2e-04
Identities = 47/196 (23%), Positives = 73/196 (37%), Gaps = 17/196 (8%)
Query: 32 PRIVTSEEVIIRDSPVL-------PVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNAS 83
PR+ + + +D PV VTL C + S +T++ T+ S
Sbjct: 1072 PRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP 1131
Query: 84 NMEYRINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMY 142
+ +I + R DSG Y CV ++ A + V P I + GQ +
Sbjct: 1132 SGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIP 1191
Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 202
C + G P P W K + M +D G + N + ++ D G Y C A
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVD-----GEHHVSNPDGTLSIDQAT---PSDAGIYTCVA 1243
Query: 203 TNAIGSASVVTVLRVR 218
TN G+ L V+
Sbjct: 1244 TNIAGTDETEITLHVQ 1259
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/215 (21%), Positives = 92/215 (42%), Gaps = 21/215 (9%)
Query: 68 WTKNGVEL--SATRKNASNMEY-RINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPD 123
W K+ V++ S+T + +N + ++ + ED+G Y C + + I+V P
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPT 1453
Query: 124 ITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
I G + +D + C+ G P PD W K +G P+ + + + +
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFK--DGKPLFLGDPNVELL----DRG 1507
Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVII 241
L++ N + D G Y+C +NA G + +++ ++ P + +I +L+ +
Sbjct: 1508 QVLHLKNAR-RNDKGRYQCTVSNAAGKQA--KDIKLTIYIPPSIKGGNVTTDISVLINSL 1564
Query: 242 VVYEKRKRPDEVP------DAGPMKTNSTNNHKDK 270
+ E R +P D P+ ++S + DK
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDK 1599
Score = 40.8 bits (94), Expect = 0.001
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 20/196 (10%)
Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT---RKNASNMEY 87
EP + E S ++ L+ +S W K+G L T +
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL 3584
Query: 88 RINKPRAEDSGEYHCVYHFVSAPKAN----ATIEVKAAPDITG--HKRSENKNEGQDATM 141
RI+ + ED+G Y C+ S+P + + V P+I G R + T+
Sbjct: 3585 RISTAQVEDTGRYTCL---ASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 142 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 201
CKS P P W + NG + + + R I++ Y ++N +L D Y C
Sbjct: 3642 ECKSDAVPPPVITWLR--NG---ERLQATPRVRILSGGRYLQINNADL---GDTANYTCV 3693
Query: 202 ATNAIGSASVVTVLRV 217
A+N G + +L V
Sbjct: 3694 ASNIAGKTTREFILTV 3709
Score = 39.3 bits (90), Expect = 0.004
Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 25/179 (13%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRAEDSGEYHCV-Y 104
PV L+C ++ + + W K+ LS + I + D+G Y CV
Sbjct: 1937 PVQLECK--AAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAI 1994
Query: 105 HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
+ A + +++V AP I+G + C++ G P P W K +G P+
Sbjct: 1995 NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLK--DGSPV 2052
Query: 165 DI------VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
V + GR L + + QI+ D G Y C A NA G LRV
Sbjct: 2053 SSFSNGLQVLSGGRI----------LALTSAQIS-DTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 38.9 bits (89), Expect = 0.005
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 14/127 (11%)
Query: 96 DSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRS-ENKN--EGQDATMYCKSVGYPHP 151
D+G Y CV + + V A P I G+ RS EN + E ++ C++ G P P
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416
Query: 152 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-EDPGEYECNATNAIGSAS 210
W K +G P+ + N+ I++ L +Q T ED G+Y C NA G
Sbjct: 2417 SITWFK--DGWPVSLSNSVR---ILSGGRMLRL----MQTTMEDAGQYTCVVRNAAGEER 2467
Query: 211 VVTVLRV 217
+ L V
Sbjct: 2468 KIFGLSV 2474
Score = 38.9 bits (89), Expect = 0.005
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 30/193 (15%)
Query: 26 GAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT--RKNAS 83
GA + P VT V++ S ++ +C SS + W K+G L K S
Sbjct: 2873 GANSDLPEEVT---VLVNKSALI----EC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLS 2923
Query: 84 NMEY-RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDA 139
N +I + D G Y CV + + K + V P + G K SEN
Sbjct: 2924 NGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-SENLTVVVNNFI 2982
Query: 140 TMYCKSVGYPHPDWIWRKKENGMPMD---IVNTSGRFFIINKENYTELNIVNLQITEDPG 196
++ C+ G+P PD W K E + ++ ++ GR L I+ +++ D G
Sbjct: 2983 SLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR----------TLQIIRAKVS-DGG 3031
Query: 197 EYECNATNAIGSA 209
EY C A N G +
Sbjct: 3032 EYTCIAINQAGES 3044
Score = 38.1 bits (87), Expect = 0.009
Identities = 41/157 (26%), Positives = 63/157 (40%), Gaps = 15/157 (9%)
Query: 68 WTKNGVELSATRKN--ASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124
WT N + + + + S+ I +D+G Y C+ + K N+T+ AP +
Sbjct: 645 WTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKL 704
Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184
+ G M CK+ G P P W K D+ F II+ L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIPPPQVKWFKG------DLELRPSTFLIID----PLL 754
Query: 185 NIVNLQITE--DPGEYECNATNAIGSASVVTVLRVRS 219
++ +Q T+ D G+Y C A N G A+ L V S
Sbjct: 755 GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791
Score = 37.0 bits (84), Expect = 0.019
Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 13/125 (10%)
Query: 88 RINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSE----NKNEGQDATMY 142
+I + + D GEY C+ + K ++ V P I H N EG ++
Sbjct: 3021 QIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLE 3080
Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 202
C+S P P W K NG ++ S I+ + L+I +++ D G+Y C A
Sbjct: 3081 CESNAVPPPVITWYK--NGR---MITESTHVEIL--ADGQMLHIKKAEVS-DTGQYVCRA 3132
Query: 203 TNAIG 207
N G
Sbjct: 3133 INVAG 3137
Score = 36.6 bits (83), Expect = 0.025
Identities = 54/210 (25%), Positives = 72/210 (34%), Gaps = 36/210 (17%)
Query: 17 VSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELS 76
V S+ PGP T+ VI+ + TL C T W KNG L+
Sbjct: 3802 VPPSIAPGP----------TNMTVIVN----VQTTLACEATGIPKPSIN--WRKNGHLLN 3845
Query: 77 ATRKNASNMEYR--------INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH 127
+ S YR I P +D+ Y C V + K + V+ P I
Sbjct: 3846 VDQNQNS---YRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE 3902
Query: 128 KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIV 187
+ A + C + G P P W K NG+ + G + I E+
Sbjct: 3903 PTDFLVTKHAPAVITCTASGVPFPSIHWTK--NGIRL---LPRGDGYRILSSGAIEILAT 3957
Query: 188 NLQITEDPGEYECNATNAIGSASVVTVLRV 217
L G Y C A NA GSA L V
Sbjct: 3958 QLN---HAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 36.2 bits (82), Expect = 0.032
Identities = 38/149 (25%), Positives = 56/149 (37%), Gaps = 15/149 (10%)
Query: 68 WTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAP 122
W NG EL+ S +E I D+GEY CV + + ++V P
Sbjct: 1300 WLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Query: 123 DITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
I ++ N + Q ++C+ G P P +W K D V + I N
Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK-------DNVQVTESSTIQTVNN 1412
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSA 209
L + ED G Y C A N G++
Sbjct: 1413 GKILKLFRAT-PEDAGRYSCKAINIAGTS 1440
Score = 35.8 bits (81), Expect = 0.042
Identities = 52/221 (23%), Positives = 81/221 (36%), Gaps = 42/221 (19%)
Query: 52 LQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVS 108
L C++T S W K+G E + + + I + + ++G Y C+
Sbjct: 1754 LDCHVTGSPPPTIM--WLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM----- 1806
Query: 109 APKANATIEVKAAPDITGHKRSENKNEG---------QDATMYCKSVGYPHPDWIWRKKE 159
AN + K ++T H K+ G + + C + G P+P W K +
Sbjct: 1807 --AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 160 NGMPMDI------VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 213
P++ + +SGR I K + ED G Y C ATNA G
Sbjct: 1865 Q--PVNTAQGNLKIQSSGRVLQIAKT-----------LLEDAGRYTCVATNAAGETQQHI 1911
Query: 214 VLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVP 254
L V H P G + +LV V E + + VP
Sbjct: 1912 QLHV--HEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVP 1950
Score = 35.4 bits (80), Expect = 0.055
Identities = 47/211 (22%), Positives = 86/211 (40%), Gaps = 38/211 (18%)
Query: 24 GPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSA---TR 79
GPG + E +I + + TL+C + S +L+ W K+G L +
Sbjct: 2676 GPGLSPKEVKIKVNNTL----------TLECEAYAIPSASLS---WYKDGQPLKSDDHVN 2722
Query: 80 KNASNMEYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVKAAPDIT-----GHKRSENK 133
A+ +I + + D+G Y CV ++ + + + ++ P G+ +
Sbjct: 2723 IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 134 N-EGQDA------TMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186
N E +D ++YC++ P P W K +G P+ +S + I+ ++
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYK--DGHPL---TSSDKVLILPGGRVLQIPR 2837
Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRV 217
+ ED G Y C A N G S+ +RV
Sbjct: 2838 AKV---EDAGRYTCVAVNEAGEDSLQYDVRV 2865
Score = 35.0 bits (79), Expect = 0.072
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 15/151 (9%)
Query: 68 WTKNGVEL-SATRKNASNMEYRINKPRAE--DSGEYHC-VYHFVSAPKANATIEVKAAPD 123
W K+G + S+++ + ++ PRA+ DS Y C V + + + ++V P
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPM 1640
Query: 124 ITGHKRSENKNE---GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
I G+ + + T+ CK+ G P P W K +G+P+ N + R K
Sbjct: 1641 IEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK--DGVPVK-ANDNIRIEAGGK-- 1695
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASV 211
+L I++ Q D G+Y C AT+ G +
Sbjct: 1696 --KLEIMSAQ-EIDRGQYICVATSVAGEKEI 1723
Score = 32.0 bits (71), Expect = 0.61
Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 15/134 (11%)
Query: 94 AEDSGEYHC-VYHFVSAPKANATIEVKA--APDITGHKRSENKNEGQDATMYCKSV-GYP 149
A D G Y C + ++ T+ V AP I N EGQ T+ C + G P
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNP 918
Query: 150 HPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209
P+ W K + + + + + V LQ D GEY C A+N G+
Sbjct: 919 IPERRWIKNSAML------LQNPYITVRSDGSLHIERVQLQ---DGGEYTCVASNVAGTN 969
Query: 210 SVVTVLRVRSHLAP 223
+ T + V H+ P
Sbjct: 970 NKTTSVVV--HVLP 981
Score = 31.2 bits (69), Expect = 1.0
Identities = 33/155 (21%), Positives = 59/155 (38%), Gaps = 12/155 (7%)
Query: 68 WTKNGVELSATR--KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDI 124
+ +NGV L + K ++++ I K D G Y C+ +A +V P +
Sbjct: 463 FVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPV 522
Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYT-E 183
+ G+ A + C + + W++ + V + I N + E
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRD-----VRLAEPARIRTLANLSLE 577
Query: 184 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
L V D GEY C ++ GS++ L V+
Sbjct: 578 LKSVKFN---DAGEYHCMVSSEGGSSAASVFLTVQ 609
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 55.1 bits (131), Expect = 7e-08
Identities = 53/233 (22%), Positives = 100/233 (42%), Gaps = 28/233 (12%)
Query: 36 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRI 89
T ++ IR + + L+C T H W K+G + A R+ ++ + I
Sbjct: 604 TPHDITIRTTTM--ARLECAATG--HPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFI 659
Query: 90 NKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148
+ +D+G Y C + + ANAT+ V P + + G+ + CK+ G
Sbjct: 660 TDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGN 719
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208
P P W K + P+ + + +N +L +V + ED G Y C +N +G+
Sbjct: 720 PPPRITWFKGDR--PLSLTERHH----LTPDN--QLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 209 ------ASVVTVLRVRSHLAPLWPF-LGILAEIII--LVVIIVVYEKRKRPDE 252
SV+ R + F + +++ I++ LV + ++Y+ RK+ +E
Sbjct: 772 ERAHSQLSVLPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEE 824
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 55.1 bits (131), Expect = 7e-08
Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 17/182 (9%)
Query: 39 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTK-NGVELSATRKNASNMEYRINKPRAEDS 97
EV+I S TL+C T H L WT+ NG+EL +R A++ + D
Sbjct: 340 EVLIGTS----TTLECMATGHPHPLIT--WTRDNGLELDGSRHVATSSGLYLQNITQRDH 393
Query: 98 GEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 156
G + C + +A A I V+A P T + + E C++ G P P +W
Sbjct: 394 GRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWT 453
Query: 157 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216
K +P++ G+ +++ ++ D G+YEC A +++G V L
Sbjct: 454 KTGGQLPVE-----GQHTVLSSGTLR----IDRAAQHDQGQYECQAVSSLGVKKVSVQLT 504
Query: 217 VR 218
V+
Sbjct: 505 VK 506
Score = 44.7 bits (104), Expect = 9e-05
Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 25/192 (13%)
Query: 34 IVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYS-----------YWTKNGVELSATRKNA 82
+ + +I++ P VT + + H + + WTK G +L ++
Sbjct: 407 VQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHT 466
Query: 83 --SNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATIEVKAAPDITGHKRSENKNEGQ 137
S+ RI++ D G+Y C V T++ KA T + + G+
Sbjct: 467 VLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGK 526
Query: 138 DATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE 197
+ + C + G P P W K+ G+ + SG+F + ++ T + D G
Sbjct: 527 NINISCHAQGEPQPIITWNKE--GVQ---ITESGKFHVDDEGTLTIYDAG----FPDQGR 577
Query: 198 YECNATNAIGSA 209
YEC A N+ G A
Sbjct: 578 YECVARNSFGLA 589
Score = 30.4 bits (67), Expect = 1.8
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 21/102 (20%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
+P IT + G C++ G P P+ IW + + + E+
Sbjct: 233 SPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDL--------------ED 278
Query: 181 YTELNIVN---LQI----TEDPGEYECNATNAIGSASVVTVL 215
T LN+ + L I D G Y+C A N+ G A + +
Sbjct: 279 DTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 54.7 bits (130), Expect = 9e-08
Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 14/185 (7%)
Query: 39 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA-SNMEYRINKPRAEDS 97
+V++ D+PV T C + W K EL R S+ I AED
Sbjct: 267 QVVLADAPV---TFLCEVKGDPPPRLR--WRKEDGELPTGRYEIRSDHSLWIGHVSAEDE 321
Query: 98 GEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 156
G Y CV + V +A+ ++ V P + + + G+ C++ G P P W+
Sbjct: 322 GTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQ 381
Query: 157 KKENGM---PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 213
K+ + + P + +GRF + + +LNI +Q D G Y C A + GS
Sbjct: 382 KEGSQVLLFPSQSLQPTGRFSVSPR---GQLNITAVQ-RGDAGYYVCQAVSVAGSILAKA 437
Query: 214 VLRVR 218
+L ++
Sbjct: 438 LLEIK 442
Score = 30.4 bits (67), Expect = 1.8
Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVN---TSGRFFIINKENYTELNIVNLQ 190
+ G+ AT+ C++ G P P+ W K NG + V + R + + + + +
Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYK--NGARVATVREDPRAHRLLLPSGALFFPRIVHGRR 133
Query: 191 ITEDPGEYECNATNAIGSAS 210
D G Y C A N +G+A+
Sbjct: 134 ARPDEGVYTCVARNYLGAAA 153
Score = 29.6 bits (65), Expect = 3.0
Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 23/134 (17%)
Query: 96 DSGEYHCVYHFVSAP-KANATIEVKAA------PDITGHKRSENKNEGQDATMYCKSVGY 148
D+G Y C V+ A A +E+K A P I ++ G + C+ G
Sbjct: 418 DAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477
Query: 149 PHPDWIWRKKENGMPMDIVN----TSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
P P W+K + D + +G +I N + D G Y C A +
Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEM------------DMGFYSCVAKS 525
Query: 205 AIGSASVVTVLRVR 218
+ G A+ L++R
Sbjct: 526 STGEATWSGWLKMR 539
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 54.3 bits (129), Expect = 1e-07
Identities = 44/135 (32%), Positives = 59/135 (43%), Gaps = 18/135 (13%)
Query: 84 NMEY--RINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDAT 140
++EY RI K D G Y C PK + + V+ P I+ NEG + T
Sbjct: 91 SLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVT 150
Query: 141 MYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-EDPGEYE 199
+ C + G P P WR + +GR F +E Y E+ L IT E G+YE
Sbjct: 151 LVCMANGRPEPVITWRH---------LTPTGREF-EGEEEYLEI----LGITREQSGKYE 196
Query: 200 CNATNAIGSASVVTV 214
C A N + SA V V
Sbjct: 197 CKAANEVSSADVKQV 211
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 9/123 (7%)
Query: 95 EDSGEYHC--VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPD 152
E SG+Y C SA + V P IT K +E G+ A++ C++ P PD
Sbjct: 190 EQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNE-ATTGRQASLKCEASAVPAPD 248
Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 212
+ W + + +N++ I + E + L + N+ E G Y C A N +G +
Sbjct: 249 FEWYRDDTR-----INSANGLEIKSTEGQSSLTVTNV-TEEHYGNYTCVAANKLGVTNAS 302
Query: 213 TVL 215
VL
Sbjct: 303 LVL 305
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 9/160 (5%)
Query: 68 WTKNGVELSATRKNA-SNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDIT 125
W K+ EL +R + +I K A D G Y CV + V +A+AT+ V+ P
Sbjct: 256 WRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 315
Query: 126 GHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG---MPMDIVNTSGRFFIINKENYT 182
R + G+ T C++ G P P WR++ + +S RF +
Sbjct: 316 VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV---SQTG 372
Query: 183 ELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222
+L I N+Q D G Y C N GS L V +A
Sbjct: 373 DLTITNVQ-RSDVGYYICQTLNVAGSIITKAYLEVTDVIA 411
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/174 (25%), Positives = 68/174 (39%), Gaps = 15/174 (8%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSAT--RKNASNMEYRINKPRAEDSGEYHCVYHF 106
P ++C T S W K+G L R + I R D+G+Y CV
Sbjct: 147 PAVMECQPPRGHPEPTIS-WKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 205
Query: 107 VSAPKANATIEVKAAPDITGHKRSENKNEGQD--ATMYCKSVGYPHPDWIWRKKENGMPM 164
+ + + E+ + KR N D A C++ G P P WRK + +P
Sbjct: 206 MVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP- 264
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
R+ I ++++T L I + D G Y C A N +G A L V+
Sbjct: 265 -----KSRYEI--RDDHT-LKIRKV-TAGDMGSYTCVAENMVGKAEASATLTVQ 309
Score = 34.7 bits (78), Expect = 0.094
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
P I H ++G+ AT+ CK+ G P P W K + D + ++ +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 182 TELNIVN-LQITEDPGEYECNATNAIGSA 209
L IV+ + D G Y C A N +G A
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEA 117
Score = 29.3 bits (64), Expect = 4.0
Identities = 41/196 (20%), Positives = 74/196 (37%), Gaps = 31/196 (15%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVE---------LSATRKNASNM-EYRINKPRAEDSGE 99
VT QC T + + W + G + S++R + S + I + D G
Sbjct: 329 VTFQCEATGNPQPAIF--WRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 386
Query: 100 YHC-----VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDAT--MYCKSVGYPHPD 152
Y C ++ T + P + N+ D T + C + G P P
Sbjct: 387 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 446
Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNAIGSAS 210
+WRK +G+ +V+T ++ E ++ ++ + D G Y C A+ G A+
Sbjct: 447 ILWRK--DGV---LVSTQD-----SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 496
Query: 211 VVTVLRVRSHLAPLWP 226
+ V+ P+ P
Sbjct: 497 WSAYIEVQEFGVPVQP 512
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 25/185 (13%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEY 87
P++V + V + SP L C L + + LT W ++ L A+ + ++
Sbjct: 517 PQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSL 571
Query: 88 RINKPRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146
I+ D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C +
Sbjct: 572 EISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSAS 631
Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203
GYP P W ++ + D V+ G I+ ED G Y C AT
Sbjct: 632 GYPTPHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQAT 679
Query: 204 NAIGS 208
N +G+
Sbjct: 680 NEVGT 684
Score = 38.9 bits (89), Expect = 0.005
Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 18/127 (14%)
Query: 95 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153
ED+G Y C + V + T+ P ++ G++A + C++ G P P
Sbjct: 669 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV 728
Query: 154 IWRKKENGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
IW + G+ M + ++SG+ I + D G Y C A N +G AS
Sbjct: 729 IWYR--GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDAS 774
Query: 211 VVTVLRV 217
L V
Sbjct: 775 AEIQLAV 781
Score = 29.3 bits (64), Expect = 4.0
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 80 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 138
+ + N + I + + G Y C +A A I V P + + G+
Sbjct: 473 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 532
Query: 139 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 194
A + C+ +G + W + +P ++GR +L ++L+I+ D
Sbjct: 533 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 580
Query: 195 PGEYECNATNAIGSASVVTVLRVR 218
G Y+C A+NA G L VR
Sbjct: 581 GGRYQCVASNANGVTRASVWLLVR 604
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 9/160 (5%)
Query: 68 WTKNGVELSATRKNA-SNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDIT 125
W K+ EL +R + +I K A D G Y CV + V +A+AT+ V+ P
Sbjct: 295 WRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 354
Query: 126 GHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG---MPMDIVNTSGRFFIINKENYT 182
R + G+ T C++ G P P WR++ + +S RF +
Sbjct: 355 VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV---SQTG 411
Query: 183 ELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222
+L I N+Q D G Y C N GS L V +A
Sbjct: 412 DLTITNVQ-RSDVGYYICQTLNVAGSIITKAYLEVTDVIA 450
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/174 (25%), Positives = 68/174 (39%), Gaps = 15/174 (8%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSAT--RKNASNMEYRINKPRAEDSGEYHCVYHF 106
P ++C T S W K+G L R + I R D+G+Y CV
Sbjct: 186 PAVMECQPPRGHPEPTIS-WKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 244
Query: 107 VSAPKANATIEVKAAPDITGHKRSENKNEGQD--ATMYCKSVGYPHPDWIWRKKENGMPM 164
+ + + E+ + KR N D A C++ G P P WRK + +P
Sbjct: 245 MVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP- 303
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
R+ I ++++T L I + D G Y C A N +G A L V+
Sbjct: 304 -----KSRYEI--RDDHT-LKIRKV-TAGDMGSYTCVAENMVGKAEASATLTVQ 348
Score = 34.7 bits (78), Expect = 0.094
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181
P I H ++G+ AT+ CK+ G P P W K + D + ++ +
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127
Query: 182 TELNIVN-LQITEDPGEYECNATNAIGSA 209
L IV+ + D G Y C A N +G A
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEA 156
Score = 29.3 bits (64), Expect = 4.0
Identities = 41/196 (20%), Positives = 74/196 (37%), Gaps = 31/196 (15%)
Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVE---------LSATRKNASNM-EYRINKPRAEDSGE 99
VT QC T + + W + G + S++R + S + I + D G
Sbjct: 368 VTFQCEATGNPQPAIF--WRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 425
Query: 100 YHC-----VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDAT--MYCKSVGYPHPD 152
Y C ++ T + P + N+ D T + C + G P P
Sbjct: 426 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 485
Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNAIGSAS 210
+WRK +G+ +V+T ++ E ++ ++ + D G Y C A+ G A+
Sbjct: 486 ILWRK--DGV---LVSTQD-----SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 535
Query: 211 VVTVLRVRSHLAPLWP 226
+ V+ P+ P
Sbjct: 536 WSAYIEVQEFGVPVQP 551
>gi|134244585 putative neuronal cell adhesion molecule [Homo
sapiens]
Length = 814
Score = 53.5 bits (127), Expect = 2e-07
Identities = 64/214 (29%), Positives = 86/214 (40%), Gaps = 39/214 (18%)
Query: 10 LALSLLLVSGSLLPGPG-----AAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT 64
L L LLL+ LLP P +A+ + S++V + P P+ L C + +
Sbjct: 20 LLLPLLLL---LLPAPSEGLGHSAELAFAVEPSDDVAV---PGQPIVLDCRVEGTPPVRI 73
Query: 65 YSYWTKNGVELSATRKNA--SNMEYRINKPRAE------DSGEYHCVYH--FVSAPKANA 114
W KNGVEL + + +N I R E D G+Y CV F A
Sbjct: 74 T--WRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKA 131
Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174
I+ D H ++ EG A C+ G P P W K N +P+D N
Sbjct: 132 RIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEK--NRVPIDTDN------ 183
Query: 175 IINKENYTELNIVNLQIT----EDPGEYECNATN 204
E YT L LQIT ED G + C A+N
Sbjct: 184 ----ERYTLLPKGVLQITGLRAEDGGIFHCVASN 213
Score = 36.6 bits (83), Expect = 0.025
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 112 ANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSG 171
A + V+A + H +S ++ G A C++ G P P W K NG ++ G
Sbjct: 320 AQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLK--NG---QVLGPGG 374
Query: 172 RFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
+ K N + L I + ED Y+C A N+ GS+ L V
Sbjct: 375 HVRL--KNNNSTLTISGIG-PEDEAIYQCVAENSAGSSQASARLTV 417
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 53.1 bits (126), Expect = 3e-07
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117
W NGVEL+ + + + S+ I + D G C+ + + + T+ E
Sbjct: 26765 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26824
Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177
+ AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I
Sbjct: 26825 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 26879
Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
N L I N ++ D G+Y A N G S L V
Sbjct: 26880 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 26918
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121
W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A
Sbjct: 24261 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 24320
Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
P G+ E +T+ + +G P P W + ++ S I N
Sbjct: 24321 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 24375
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
E+YT L + N+Q G+Y+ +N G+ + + ++
Sbjct: 24376 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24415
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%)
Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168
A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I
Sbjct: 888 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 947
Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
SG ++ +E + ED G + C+A N G+ S L V+
Sbjct: 948 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 37.7 bits (86), Expect = 0.011
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
+EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q +
Sbjct: 27036 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 27091
Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219
D G Y + N GS S + +RS
Sbjct: 27092 DGGLYTLSLGNEFGSDSATVNIHIRS 27117
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I + G+ A + C+ VG P PD W + + R + ++ +
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 24280
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
T V + ED G Y C ATN +G + L +++
Sbjct: 24281 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24319
Score = 36.6 bits (83), Expect = 0.025
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 89 INKPRAED-SGEYHCVYHFVS---APKANATIEVKAAPDITGHKRSENKNEGQDATMYCK 144
I+K ED GEY C S A A T+ +AAP I G A C+
Sbjct: 4492 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCE 4551
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
P+ + W K + S + I + + + L I+ Q+ D GEY C A+N
Sbjct: 4552 IQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DCGEYTCKASN 4605
Query: 205 AIGSASVVTVLRV 217
GS S L V
Sbjct: 4606 EYGSVSCTATLTV 4618
Score = 35.4 bits (80), Expect = 0.055
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D +
Sbjct: 24614 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 24670
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
+ F K Y +L I ++ +D Y+ ATN GS S L V
Sbjct: 24671 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 24714
Score = 34.7 bits (78), Expect = 0.094
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D
Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1478
Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219
GE+ A N G +S+ +L V +
Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEA 1503
Score = 34.7 bits (78), Expect = 0.094
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%)
Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119
W +N + + K+ E +I+ KPR D GEY F++ K A A +E+
Sbjct: 6639 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 6692
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170
AAP I + + G+ TM YP + W K+ + ++T+
Sbjct: 6693 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 6752
Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196
GR+ I+ NK E +NL++ + PG
Sbjct: 6753 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 6786
Score = 33.1 bits (74), Expect = 0.27
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
+G A VG P P W K+ + TS + II+ N + IVN ED
Sbjct: 3780 QGLPAIFEYTVVGEPAPTVTWFKENKQLC-----TSVYYTIIHNPNGSGTFIVNDPQRED 3834
Query: 195 PGEYECNATNAIGSASVVTVLRV 217
G Y C A N +G ++ L V
Sbjct: 3835 SGLYICKAENMLGESTCAAELLV 3857
Score = 32.3 bits (72), Expect = 0.47
Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%)
Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133
+++ TR++ S+ E+ + + E + + K T+ + I RS
Sbjct: 26212 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 26267
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
EG+ A C + G P P W +K +++TS R + + + I ++Q
Sbjct: 26268 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 26321
Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218
D G Y N+ G L ++
Sbjct: 26322 DEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
K PDI + EG+ A C+ GYP P W NG ++ S R F +
Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1845
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207
+ L+IV+ + + D GE + A N G
Sbjct: 1846 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1873
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193
EGQ + G P P W K +G P+ + II++ +Y L+I + + E
Sbjct: 25503 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 25556
Query: 194 DPGEYECNATNAIGSASVVTVLRV 217
D G Y ATN GS S L+V
Sbjct: 25557 DTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 31.2 bits (69), Expect = 1.0
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194
G+D + G P P WRK E + D R+ I N ++ + L I Q+T D
Sbjct: 20981 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 21033
Query: 195 PGEYECNATNAIGSASVVTV 214
G+Y N +G TV
Sbjct: 21034 TGKYILTIENGVGEPKSSTV 21053
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2086
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
EL ++ ED A N G S L V++
Sbjct: 2087 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124
Score = 30.8 bits (68), Expect = 1.4
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114
SH S W KNGVE+ + K ++ ++++ EDS EY V + +A
Sbjct: 2860 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2916
Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174
T+ V P + + E +D + +V Y + W K NG+ + ++ +
Sbjct: 2917 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 2969
Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216
+ K+ LNI N+ D +Y A A +A++ R
Sbjct: 2970 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3010
Score = 30.8 bits (68), Expect = 1.4
Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101
TL C +T H W + G E+ A ++YRI E G YH
Sbjct: 24641 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 24689
Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148
VY + + A++EV+ I K E G+ ++ G
Sbjct: 24690 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 24749
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
P P W+K + D+++ +G + +I ++T L N +D G Y A N G
Sbjct: 24750 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24803
Score = 30.8 bits (68), Expect = 1.4
Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PKA I K P I + + A K+ G P P IW K + T
Sbjct: 26537 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 26588
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
G + ++++ ++ T D G Y C N+ GS S L +++
Sbjct: 26589 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26638
Score = 30.4 bits (67), Expect = 1.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P +W K+E + D R I N +EL I+ + +D G Y ATN+
Sbjct: 8825 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 8877
Query: 207 GS 208
GS
Sbjct: 8878 GS 8879
Score = 29.6 bits (65), Expect = 3.0
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179
A P+ +S +G + + G P P + + +G + S F I++E
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155
Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
++ ED G Y NATN++G A+ L V+
Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 29.3 bits (64), Expect = 4.0
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EG T +CK GYP P W K +G + F+ + + +V + ED
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1312
Query: 195 PGEYECNATNAIGSA 209
G Y A+N G+A
Sbjct: 1313 EGIYTAFASNIKGNA 1327
Score = 29.3 bits (64), Expect = 4.0
Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P W + + D + + +N++ + + + D GEY+ +NA
Sbjct: 11231 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 11284
Query: 207 GSASVVTVLRV 217
GS +V L V
Sbjct: 11285 GSKTVAVHLTV 11295
Score = 28.9 bits (63), Expect = 5.2
Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+
Sbjct: 12619 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 12672
Query: 207 GS 208
G+
Sbjct: 12673 GT 12674
Score = 28.5 bits (62), Expect = 6.8
Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP T +S EG AT G+P P+ W + +G + G I +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
+L I + + G Y ATN G A+ L V++ AP
Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103
Score = 28.1 bits (61), Expect = 8.8
Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149
DSGE+ V +S +E + P ++ N EG M ++ G P
Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 150 HPDWIWRKKEN 160
+PD +W K +
Sbjct: 1538 NPDIVWLKNSD 1548
Score = 28.1 bits (61), Expect = 8.8
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
G P P W K E + P D + + + + E TEL+I + ED G Y A+N
Sbjct: 9119 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 9176
Query: 205 AIGS 208
+GS
Sbjct: 9177 RLGS 9180
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 53.1 bits (126), Expect = 3e-07
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117
W NGVEL+ + + + S+ I + D G C+ + + + T+ E
Sbjct: 26698 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26757
Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177
+ AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I
Sbjct: 26758 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 26812
Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
N L I N ++ D G+Y A N G S L V
Sbjct: 26813 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 26851
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121
W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A
Sbjct: 24194 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 24253
Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
P G+ E +T+ + +G P P W + ++ S I N
Sbjct: 24254 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 24308
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
E+YT L + N+Q G+Y+ +N G+ + + ++
Sbjct: 24309 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24348
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%)
Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168
A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I
Sbjct: 888 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 947
Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
SG ++ +E + ED G + C+A N G+ S L V+
Sbjct: 948 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 37.7 bits (86), Expect = 0.011
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
+EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q +
Sbjct: 26969 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 27024
Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219
D G Y + N GS S + +RS
Sbjct: 27025 DGGLYTLSLGNEFGSDSATVNIHIRS 27050
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I + G+ A + C+ VG P PD W + + R + ++ +
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 24213
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
T V + ED G Y C ATN +G + L +++
Sbjct: 24214 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24252
Score = 36.6 bits (83), Expect = 0.025
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 89 INKPRAED-SGEYHCVYHFVS---APKANATIEVKAAPDITGHKRSENKNEGQDATMYCK 144
I+K ED GEY C S A A T+ +AAP I G A C+
Sbjct: 4425 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCE 4484
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
P+ + W K + S + I + + + L I+ Q+ D GEY C A+N
Sbjct: 4485 IQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DCGEYTCKASN 4538
Query: 205 AIGSASVVTVLRV 217
GS S L V
Sbjct: 4539 EYGSVSCTATLTV 4551
Score = 35.4 bits (80), Expect = 0.055
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D +
Sbjct: 24547 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 24603
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
+ F K Y +L I ++ +D Y+ ATN GS S L V
Sbjct: 24604 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 24647
Score = 34.7 bits (78), Expect = 0.094
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D
Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1478
Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219
GE+ A N G +S+ +L V +
Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEA 1503
Score = 34.7 bits (78), Expect = 0.094
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%)
Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119
W +N + + K+ E +I+ KPR D GEY F++ K A A +E+
Sbjct: 6572 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 6625
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170
AAP I + + G+ TM YP + W K+ + ++T+
Sbjct: 6626 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 6685
Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196
GR+ I+ NK E +NL++ + PG
Sbjct: 6686 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 6719
Score = 33.1 bits (74), Expect = 0.27
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
+G A VG P P W K+ + TS + II+ N + IVN ED
Sbjct: 3713 QGLPAIFEYTVVGEPAPTVTWFKENKQLC-----TSVYYTIIHNPNGSGTFIVNDPQRED 3767
Query: 195 PGEYECNATNAIGSASVVTVLRV 217
G Y C A N +G ++ L V
Sbjct: 3768 SGLYICKAENMLGESTCAAELLV 3790
Score = 32.3 bits (72), Expect = 0.47
Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%)
Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133
+++ TR++ S+ E+ + + E + + K T+ + I RS
Sbjct: 26145 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 26200
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
EG+ A C + G P P W +K +++TS R + + + I ++Q
Sbjct: 26201 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 26254
Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218
D G Y N+ G L ++
Sbjct: 26255 DEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
K PDI + EG+ A C+ GYP P W NG ++ S R F +
Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1845
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207
+ L+IV+ + + D GE + A N G
Sbjct: 1846 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1873
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193
EGQ + G P P W K +G P+ + II++ +Y L+I + + E
Sbjct: 25436 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 25489
Query: 194 DPGEYECNATNAIGSASVVTVLRV 217
D G Y ATN GS S L+V
Sbjct: 25490 DTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 31.2 bits (69), Expect = 1.0
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194
G+D + G P P WRK E + D R+ I N ++ + L I Q+T D
Sbjct: 20914 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 20966
Query: 195 PGEYECNATNAIGSASVVTV 214
G+Y N +G TV
Sbjct: 20967 TGKYILTIENGVGEPKSSTV 20986
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2086
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
EL ++ ED A N G S L V++
Sbjct: 2087 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124
Score = 30.8 bits (68), Expect = 1.4
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114
SH S W KNGVE+ + K ++ ++++ EDS EY V + +A
Sbjct: 2860 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2916
Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174
T+ V P + + E +D + +V Y + W K NG+ + ++ +
Sbjct: 2917 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 2969
Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216
+ K+ LNI N+ D +Y A A +A++ R
Sbjct: 2970 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3010
Score = 30.8 bits (68), Expect = 1.4
Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101
TL C +T H W + G E+ A ++YRI E G YH
Sbjct: 24574 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 24622
Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148
VY + + A++EV+ I K E G+ ++ G
Sbjct: 24623 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 24682
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
P P W+K + D+++ +G + +I ++T L N +D G Y A N G
Sbjct: 24683 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24736
Score = 30.8 bits (68), Expect = 1.4
Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PKA I K P I + + A K+ G P P IW K + T
Sbjct: 26470 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 26521
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
G + ++++ ++ T D G Y C N+ GS S L +++
Sbjct: 26522 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26571
Score = 30.4 bits (67), Expect = 1.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P +W K+E + D R I N +EL I+ + +D G Y ATN+
Sbjct: 8758 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 8810
Query: 207 GS 208
GS
Sbjct: 8811 GS 8812
Score = 30.0 bits (66), Expect = 2.3
Identities = 19/84 (22%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
+ G+ + + G P P+ W + I+ T F + L ++ +E
Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQL----ILPTKDVVFHFEESTGMALMLIVDAYSE 3486
Query: 194 DPGEYECNATNAIGSASVVTVLRV 217
G+Y C A N+ G A+ L V
Sbjct: 3487 HAGQYSCKAANSAGEATCAATLTV 3510
Score = 29.6 bits (65), Expect = 3.0
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179
A P+ +S +G + + G P P + + +G + S F I++E
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155
Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
++ ED G Y NATN++G A+ L V+
Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 29.3 bits (64), Expect = 4.0
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EG T +CK GYP P W K +G + F+ + + +V + ED
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1312
Query: 195 PGEYECNATNAIGSA 209
G Y A+N G+A
Sbjct: 1313 EGIYTAFASNIKGNA 1327
Score = 29.3 bits (64), Expect = 4.0
Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P W + + D + + +N++ + + + D GEY+ +NA
Sbjct: 11164 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 11217
Query: 207 GSASVVTVLRV 217
GS +V L V
Sbjct: 11218 GSKTVAVHLTV 11228
Score = 28.9 bits (63), Expect = 5.2
Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+
Sbjct: 12552 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 12605
Query: 207 GS 208
G+
Sbjct: 12606 GT 12607
Score = 28.5 bits (62), Expect = 6.8
Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP T +S EG AT G+P P+ W + +G + G I +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
+L I + + G Y ATN G A+ L V++ AP
Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103
Score = 28.1 bits (61), Expect = 8.8
Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149
DSGE+ V +S +E + P ++ N EG M ++ G P
Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 150 HPDWIWRKKEN 160
+PD +W K +
Sbjct: 1538 NPDIVWLKNSD 1548
Score = 28.1 bits (61), Expect = 8.8
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
G P P W K E + P D + + + + E TEL+I + ED G Y A+N
Sbjct: 9052 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 9109
Query: 205 AIGS 208
+GS
Sbjct: 9110 RLGS 9113
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 53.1 bits (126), Expect = 3e-07
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117
W NGVEL+ + + + S+ I + D G C+ + + + T+ E
Sbjct: 26573 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26632
Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177
+ AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I
Sbjct: 26633 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 26687
Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
N L I N ++ D G+Y A N G S L V
Sbjct: 26688 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 26726
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121
W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A
Sbjct: 24069 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 24128
Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
P G+ E +T+ + +G P P W + ++ S I N
Sbjct: 24129 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 24183
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
E+YT L + N+Q G+Y+ +N G+ + + ++
Sbjct: 24184 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24223
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%)
Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168
A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I
Sbjct: 888 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 947
Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
SG ++ +E + ED G + C+A N G+ S L V+
Sbjct: 948 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 37.7 bits (86), Expect = 0.011
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
+EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q +
Sbjct: 26844 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 26899
Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219
D G Y + N GS S + +RS
Sbjct: 26900 DGGLYTLSLGNEFGSDSATVNIHIRS 26925
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I + G+ A + C+ VG P PD W + + R + ++ +
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 24088
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
T V + ED G Y C ATN +G + L +++
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127
Score = 36.6 bits (83), Expect = 0.025
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 89 INKPRAED-SGEYHCVYHFVS---APKANATIEVKAAPDITGHKRSENKNEGQDATMYCK 144
I+K ED GEY C S A A T+ +AAP I G A C+
Sbjct: 4300 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCE 4359
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
P+ + W K + S + I + + + L I+ Q+ D GEY C A+N
Sbjct: 4360 IQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DCGEYTCKASN 4413
Query: 205 AIGSASVVTVLRV 217
GS S L V
Sbjct: 4414 EYGSVSCTATLTV 4426
Score = 35.4 bits (80), Expect = 0.055
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D +
Sbjct: 24422 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 24478
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217
+ F K Y +L I ++ +D Y+ ATN GS S L V
Sbjct: 24479 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 24522
Score = 34.7 bits (78), Expect = 0.094
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D
Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1478
Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219
GE+ A N G +S+ +L V +
Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEA 1503
Score = 34.7 bits (78), Expect = 0.094
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%)
Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119
W +N + + K+ E +I+ KPR D GEY F++ K A A +E+
Sbjct: 6447 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 6500
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170
AAP I + + G+ TM YP + W K+ + ++T+
Sbjct: 6501 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 6560
Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196
GR+ I+ NK E +NL++ + PG
Sbjct: 6561 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 6594
Score = 33.1 bits (74), Expect = 0.27
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
+G A VG P P W K+ + TS + II+ N + IVN ED
Sbjct: 3588 QGLPAIFEYTVVGEPAPTVTWFKENKQLC-----TSVYYTIIHNPNGSGTFIVNDPQRED 3642
Query: 195 PGEYECNATNAIGSASVVTVLRV 217
G Y C A N +G ++ L V
Sbjct: 3643 SGLYICKAENMLGESTCAAELLV 3665
Score = 32.3 bits (72), Expect = 0.47
Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%)
Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133
+++ TR++ S+ E+ + + E + + K T+ + I RS
Sbjct: 26020 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 26075
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
EG+ A C + G P P W +K +++TS R + + + I ++Q
Sbjct: 26076 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 26129
Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218
D G Y N+ G L ++
Sbjct: 26130 DEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178
K PDI + EG+ A C+ GYP P W NG ++ S R F +
Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1845
Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207
+ L+IV+ + + D GE + A N G
Sbjct: 1846 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1873
Score = 31.6 bits (70), Expect = 0.80
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193
EGQ + G P P W K +G P+ + II++ +Y L+I + + E
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 25364
Query: 194 DPGEYECNATNAIGSASVVTVLRV 217
D G Y ATN GS S L+V
Sbjct: 25365 DTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 31.2 bits (69), Expect = 1.0
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194
G+D + G P P WRK E + D R+ I N ++ + L I Q+T D
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 20841
Query: 195 PGEYECNATNAIGSASVVTV 214
G+Y N +G TV
Sbjct: 20842 TGKYILTIENGVGEPKSSTV 20861
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2086
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
EL ++ ED A N G S L V++
Sbjct: 2087 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124
Score = 30.8 bits (68), Expect = 1.4
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114
SH S W KNGVE+ + K ++ ++++ EDS EY V + +A
Sbjct: 2860 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2916
Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174
T+ V P + + E +D + +V Y + W K NG+ + ++ +
Sbjct: 2917 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 2969
Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216
+ K+ LNI N+ D +Y A A +A++ R
Sbjct: 2970 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3010
Score = 30.8 bits (68), Expect = 1.4
Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101
TL C +T H W + G E+ A ++YRI E G YH
Sbjct: 24449 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 24497
Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148
VY + + A++EV+ I K E G+ ++ G
Sbjct: 24498 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 24557
Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
P P W+K + D+++ +G + +I ++T L N +D G Y A N G
Sbjct: 24558 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24611
Score = 30.8 bits (68), Expect = 1.4
Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%)
Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169
PKA I K P I + + A K+ G P P IW K + T
Sbjct: 26345 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 26396
Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
G + ++++ ++ T D G Y C N+ GS S L +++
Sbjct: 26397 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446
Score = 30.4 bits (67), Expect = 1.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P +W K+E + D R I N +EL I+ + +D G Y ATN+
Sbjct: 8633 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 8685
Query: 207 GS 208
GS
Sbjct: 8686 GS 8687
Score = 29.6 bits (65), Expect = 3.0
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179
A P+ +S +G + + G P P + + +G + S F I++E
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155
Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218
++ ED G Y NATN++G A+ L V+
Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 29.3 bits (64), Expect = 4.0
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
EG T +CK GYP P W K +G + F+ + + +V + ED
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1312
Query: 195 PGEYECNATNAIGSA 209
G Y A+N G+A
Sbjct: 1313 EGIYTAFASNIKGNA 1327
Score = 29.3 bits (64), Expect = 4.0
Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G P P W + + D + + +N++ + + + D GEY+ +NA
Sbjct: 11039 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 11092
Query: 207 GSASVVTVLRV 217
GS +V L V
Sbjct: 11093 GSKTVAVHLTV 11103
Score = 28.9 bits (63), Expect = 5.2
Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206
G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+
Sbjct: 12427 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 12480
Query: 207 GS 208
G+
Sbjct: 12481 GT 12482
Score = 28.5 bits (62), Expect = 6.8
Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180
AP T +S EG AT G+P P+ W + +G + G I +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61
Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223
+L I + + G Y ATN G A+ L V++ AP
Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103
Score = 28.1 bits (61), Expect = 8.8
Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149
DSGE+ V +S +E + P ++ N EG M ++ G P
Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 150 HPDWIWRKKEN 160
+PD +W K +
Sbjct: 1538 NPDIVWLKNSD 1548
Score = 28.1 bits (61), Expect = 8.8
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
G P P W K E + P D + + + + E TEL+I + ED G Y A+N
Sbjct: 8927 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 8984
Query: 205 AIGS 208
+GS
Sbjct: 8985 RLGS 8988
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 53.1 bits (126), Expect = 3e-07
Identities = 59/247 (23%), Positives = 96/247 (38%), Gaps = 40/247 (16%)
Query: 10 LALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQC--NLTSSSHTLT 64
L+ + L + G G + E RI+ E+ +D V+ P T+Q N+ +++ L
Sbjct: 169 LSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLG 228
Query: 65 YSY---------------WTKNGVELSATRKNAS------NMEYRINKPRAEDSGEYHCV 103
S WTK+G ++ + + + I K D EY C+
Sbjct: 229 QSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICI 288
Query: 104 YHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
A + +ATI +K A P IT + + T+ C++ G P P WR
Sbjct: 289 AEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRN 347
Query: 162 M----------PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 211
+ P G + + + L + ++Q T D GEY C A+N IG S
Sbjct: 348 ISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTASNTIGQDSQ 406
Query: 212 VTVLRVR 218
L V+
Sbjct: 407 SMYLEVQ 413
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query: 54 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 106
C + + S+++ NG +L+ ++ S + I +D+G Y CV
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100
Query: 107 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164
++ AT+ VK + + EG+DA + C V P IW+ K
Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156
Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
D++ FI+ NY ++ + D G Y C
Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189
Score = 37.7 bits (86), Expect = 0.011
Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 26/131 (19%)
Query: 96 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154
D+GEY C + + + +EV+ AP + G EG + C+ YP
Sbjct: 389 DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATIS 447
Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECNATN 204
W + +P NY+ + I N L++T D G Y C A N
Sbjct: 448 WFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 493
Query: 205 AIGSASVVTVL 215
IG S+ +L
Sbjct: 494 RIGQESLEFIL 504
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 52.4 bits (124), Expect = 4e-07
Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 17/160 (10%)
Query: 68 WTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124
W K G+ ++ + + + RI ED+G Y C+ + + + V+ P I
Sbjct: 2790 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 2849
Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184
+ EG A + CK+ G P P+ W K +G P + G+F I + EL
Sbjct: 2850 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--VSGAEGKFTI---QPSGEL 2902
Query: 185 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 224
+ NL+ +D G Y C A NA+G A R R HL L
Sbjct: 2903 LVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 2935
Score = 50.1 bits (118), Expect = 2e-06
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 12/162 (7%)
Query: 67 YWTKNGVEL--SATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123
+W K+G+ L S R N I++ +D+G Y C+ + + K + +++AP
Sbjct: 3060 HWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPV 3119
Query: 124 ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 183
+ G D + C++ G P P W + G P+ S R + +
Sbjct: 3120 FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQA--GQPL---RASRRLRTLPDGSLWL 3174
Query: 184 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLW 225
N+ T D G Y+C A N +GSA+ L VR W
Sbjct: 3175 ENVE----TGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSW 3212
Score = 44.3 bits (103), Expect = 1e-04
Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 25/220 (11%)
Query: 17 VSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNG 72
V+GS G N P +T + PVL PV L CN T + S TL W K+G
Sbjct: 770 VAGSTELRYGLRVNVPPRITLPPSL--PGPVLVNTPVRLTCNATGAPSPTLM---WLKDG 824
Query: 73 VELSATRKNASNM-----EYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITG 126
+S + + RA DSG Y CV V + + ++V P I G
Sbjct: 825 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 884
Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186
+ + + + + C+S P P W K +G P++ G +K L
Sbjct: 885 EELNVSVVANESVALECQSHAMPPPVLSWWK--DGRPLE--PRPGVHLSADK----ALLQ 936
Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWP 226
V+ D G Y C A N G + L V +AP++P
Sbjct: 937 VDRADVWDAGHYTCEALNQAGRSEKHYNLNV--WVAPVFP 974
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 9/123 (7%)
Query: 96 DSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154
DSG+Y C + + A +E+ P I + N + Q A + C++ G P P
Sbjct: 2455 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVS 2514
Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214
WRK + +P+D S RF I+ + + + + +D G Y C A+N+ GS
Sbjct: 2515 WRK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRD 2566
Query: 215 LRV 217
LRV
Sbjct: 2567 LRV 2569
Score = 42.0 bits (97), Expect = 6e-04
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 88 RINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQD--ATMYCK 144
RI D G Y CV + +A + + V A P I G + +D + C+
Sbjct: 275 RITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCE 334
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
+ G P P+ W K +P TS + ++ +L + Q + D G Y C A+N
Sbjct: 335 ARGVPTPNITWFKDGALLP-----TSTK--VVYTRGGRQLQLGRAQ-SSDAGVYTCKASN 386
Query: 205 AIGSASVVTVLRV 217
A+G+A T L V
Sbjct: 387 AVGAAEKATRLDV 399
Score = 42.0 bits (97), Expect = 6e-04
Identities = 41/167 (24%), Positives = 66/167 (39%), Gaps = 19/167 (11%)
Query: 52 LQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCVY-HFV 107
L CN+T H W K+G L+ A + + ++ + +G Y C+ + V
Sbjct: 1274 LMCNVTG--HPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV 1331
Query: 108 SAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENGM 162
+ + V AP I G E ++ C+++ +P P+ W K +G
Sbjct: 1332 GEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DGA 1389
Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209
P + I L I+N Q ED G+Y C TN +G A
Sbjct: 1390 PFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 1430
Score = 41.6 bits (96), Expect = 8e-04
Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 22/184 (11%)
Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYH 105
PV L+C + H W G+ E + +R R+ P SG Y CV
Sbjct: 422 PVALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-- 477
Query: 106 FVSAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKE 159
S+P A ++EV+ P + + GQ + C++ G P P W +
Sbjct: 478 -ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--Q 534
Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
NG P + +G + T L+I ++++ + G + C ATN G+A + V
Sbjct: 535 NGRPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHG 588
Query: 220 HLAP 223
AP
Sbjct: 589 EWAP 592
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 11/123 (8%)
Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE--NKNEGQDATMYCK 144
++ + + +DSG Y C+ + + N ++EV P I E +GQ A + C
Sbjct: 1218 KMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCN 1277
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
G+P P W K +G P+ G I+ + L ++ ++ G Y C A N
Sbjct: 1278 VTGHPQPKLTWFK--DGRPL----ARGDAHHISPDGVL-LQVLQANLS-SAGHYSCIAAN 1329
Query: 205 AIG 207
A+G
Sbjct: 1330 AVG 1332
Score = 40.0 bits (92), Expect = 0.002
Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 16/166 (9%)
Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNG--VELSATRKNASNM-EYRINKPRAEDSGEYHCVY 104
P+ L C+++ + T+T W K+ VE SA S ++++ + +G Y CV
Sbjct: 1950 PLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 2006
Query: 105 HFVSAP-KANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161
A + + + V AP I +G R + EGQ+ + C++ G P PD W K +
Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 2066
Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
+ D + RF++ + L + L+ D G Y C A N G
Sbjct: 2067 LGQD-MGPHLRFYL----DGGSLVLKGLR-ASDAGAYTCVAHNPAG 2106
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 23/184 (12%)
Query: 45 SPVLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV 103
+P P+ L C+ + +T W K+G L+ N+ R D+G Y C+
Sbjct: 2317 TPGAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCL 2369
Query: 104 YHF-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKE 159
A + + + V+A P+I G + GQ + C P P W +
Sbjct: 2370 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR-- 2426
Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219
+G+ ++ + + +L ++ T D G+Y C A NA GS SV RV
Sbjct: 2427 DGI---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEI 2478
Query: 220 HLAP 223
H P
Sbjct: 2479 HTVP 2482
Score = 38.5 bits (88), Expect = 0.007
Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 15/134 (11%)
Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146
+I K D G Y C + K ++V P+I ++ E T+ C +
Sbjct: 660 QIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 719
Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203
G P PD W K + + V+ GR L I Q++ D G Y C A+
Sbjct: 720 GVPPPDVSWFKGHQPVSSWMGVTVSVDGRV----------LRIEQAQLS-DAGSYRCVAS 768
Query: 204 NAIGSASVVTVLRV 217
N GS + LRV
Sbjct: 769 NVAGSTELRYGLRV 782
Score = 37.4 bits (85), Expect = 0.015
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 96 DSGEYHC-VYHFVSAPKANATIEVKAAPDIT--GHKRSENKNEGQDATMYCKSVGYPHPD 152
DSG+Y C + V + A + V P I G K + + GQ T+ C + G+P P+
Sbjct: 68 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPE 127
Query: 153 WIWRKKEN--GMPM 164
+W K G+P+
Sbjct: 128 IVWLKDAQLVGVPL 141
Score = 36.2 bits (82), Expect = 0.032
Identities = 42/204 (20%), Positives = 75/204 (36%), Gaps = 29/204 (14%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNME 86
P + EE+ + V L+C SH + W K+G L +A
Sbjct: 879 PPSILGEELNVSVVANESVALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 934
Query: 87 YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCK 144
++++ D+G Y C + + + + V AP + EG ++ C+
Sbjct: 935 LQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCE 994
Query: 145 SVGYPHPDWIWRKKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199
G P P WRK +P + V+ GR + + + G Y
Sbjct: 995 CRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYT 1043
Query: 200 CNATNAIGSASVVTVLRVRSHLAP 223
C +N +G++S L++ H+ P
Sbjct: 1044 CECSNVVGNSS--QDLQLEVHVPP 1065
Score = 35.4 bits (80), Expect = 0.055
Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
Query: 93 RAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVG 147
RAE++G Y C + V + + V P I G N ++ C ++G
Sbjct: 1621 RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALG 1680
Query: 148 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207
P P W +NG+P + S R ++ +++ + D Y C A N G
Sbjct: 1681 NPVPTISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAG 1732
Query: 208 SASVVTVLRVR 218
SA + LRV+
Sbjct: 1733 SAEKLFTLRVQ 1743
Score = 34.7 bits (78), Expect = 0.094
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 17/73 (23%)
Query: 143 CKSVGYPHPDWIWRKKEN-----GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE 197
C + G P P WRK + G P V G F+ + D G+
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS------------PADSGD 71
Query: 198 YECNATNAIGSAS 210
YEC ATN +GS S
Sbjct: 72 YECQATNEVGSTS 84
Score = 34.3 bits (77), Expect = 0.12
Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 33/200 (16%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
P + ++ + + PV L C+ T + T++ W+K G +L A YR++
Sbjct: 2665 PPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVS 2716
Query: 91 KPRAED--------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATM 141
A + +G Y C + + + V+A+P + ++ +
Sbjct: 2717 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLL 2776
Query: 142 YCKSVGYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEY 198
C++ G P P W+K+ + + V G+ I + ED G Y
Sbjct: 2777 PCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNY 2824
Query: 199 ECNATNAIGSASVVTVLRVR 218
C A N+ GSA T L V+
Sbjct: 2825 LCIAKNSAGSAMGKTRLVVQ 2844
Score = 33.5 bits (75), Expect = 0.21
Identities = 39/185 (21%), Positives = 70/185 (37%), Gaps = 17/185 (9%)
Query: 38 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRA 94
EEV + S V+LQC + + + W +NG+ S + + +++
Sbjct: 1662 EEVTVNASST--VSLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1717
Query: 95 EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPD 152
D+ Y CV + + + T+ V+ P I G + ++ C +P+P+
Sbjct: 1718 ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE 1777
Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 212
W K + + F++ + +L L D G Y C A NA G +
Sbjct: 1778 VTWYKDSQALSL-----GEEVFLLPGTHTLQLGRARLS---DSGMYTCEALNAAGRDQKL 1829
Query: 213 TVLRV 217
L V
Sbjct: 1830 VQLSV 1834
Score = 32.0 bits (71), Expect = 0.61
Identities = 42/189 (22%), Positives = 73/189 (38%), Gaps = 28/189 (14%)
Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSH-TLTYSYWTKNG----VELSATRKNASNME 86
PR ++ +++D TL+CN T T+T W ++G EL +N
Sbjct: 1070 PREPPTQVSVVQDGVA---TLECNATGKPPPTVT---WERDGQPVGAELGLQLQN-QGQS 1122
Query: 87 YRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEG---QDATMY 142
+ + +A +G Y CV + + + V P++ G T+
Sbjct: 1123 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 1182
Query: 143 CKSVGYPHPDWIWRKKENGMPM--DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
C+++G P P W + E + D +G + + K T+ +D G Y C
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWML--KMTQTQ--------EQDSGLYSC 1232
Query: 201 NATNAIGSA 209
A+N G A
Sbjct: 1233 LASNEAGEA 1241
Score = 31.2 bits (69), Expect = 1.0
Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 8/73 (10%)
Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194
E A +YC + P PD W +++ + + ++ ++ +V E+
Sbjct: 1573 ENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR---AEN 1624
Query: 195 PGEYECNATNAIG 207
G Y C A+N +G
Sbjct: 1625 AGRYSCKASNEVG 1637
Score = 30.0 bits (66), Expect = 2.3
Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 12/125 (9%)
Query: 89 INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCK 144
+ + + G Y C + V + +EV P I G + + + QD AT+ C
Sbjct: 1031 LGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECN 1090
Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204
+ G P P W + +G P+ G + +N + V G Y C A N
Sbjct: 1091 ATGKPPPTVTWER--DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN 1142
Query: 205 AIGSA 209
G A
Sbjct: 1143 LAGRA 1147
Score = 29.3 bits (64), Expect = 4.0
Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 25/205 (12%)
Query: 26 GAAQNEPRIVTSEEVIIRDS-PVLPVT------LQCNLTSSSH-TLTYSYWTKNGVELSA 77
G+A + R+V +I + P L T L C S +T W K+G +S
Sbjct: 2833 GSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT---WDKDGQPVSG 2889
Query: 78 TRKNAS---NMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENK 133
+ + E + +D+G Y C + V + + + P T +
Sbjct: 2890 AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 2949
Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193
G + C + G P P W + + T G + ++ + L + E
Sbjct: 2950 RLGDRLWLRCAARGSPTPRIGWTVNDRPV------TEG---VSEQDGGSTLQRAAVS-RE 2999
Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218
D G Y C A N +G V+ + V+
Sbjct: 3000 DSGTYVCWAENRVGRTQAVSFVHVK 3024
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,103,992
Number of Sequences: 37866
Number of extensions: 489097
Number of successful extensions: 2377
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 107
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 1182
Number of HSP's gapped (non-prelim): 1001
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.